LOCUS       gnlProkkaJGKMBKEH_3    22954 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JGKMBKEH_3.
ACCESSION   gnlProkkaJGKMBKEH_3
VERSION     gnlProkkaJGKMBKEH_3
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 03:00:15
            Original ID  :: gnl|Prokka|JGKMBKEH_3
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 27671
            Orig. end    :: 50625
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22954
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12954]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12954
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..22954
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="interleaved"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..22954
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     protocluster    235..21467
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10234:11467]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      10235..11467
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
     CDS             394..933
                     /locus_tag="ctg3_25"
                     /transl_table=11
                     /translation="METNKPTLYWSLLMFKDWNFYIASTLKGLVFVGSQNKPIEELFEW
                     ARKRFPGSLLVEDDDKLEPYAVEITQYLEGKRKNFTVPVEYAGTQFQLAVWNALCEIPY
                     GQTKSYSDIANEINKPAAVRAVGAAIGANPVLITVPCHRVIGKNGSLTGYRGGFEMKTL
                     LLDLEKRASSEMDVPH"
     CDS             1444..2961
                     /locus_tag="ctg3_26"
                     /transl_table=11
                     /translation="MLVSLSLSSLLTLFFIMLMASGISGLLFLHPRVPLSFVRIHIGIL
                     ALPLLVSLLILADSGVSGNVGPWHLDSLACLMTFFVLAIGFIIQRFSLRYLMGDRSYRK
                     YFTLFTFTTGAASMTWLSGDLRLMLLFWGATLVGLTLLIRLNSAWQVASEAAKVSGRLF
                     LLSWFSLFFAMMWLFHATGQWQLSLVVTNESLAGLGEWERTGIQLLIVLAVIIPAAQWP
                     FQRWLVESIVAPTPVSAIMHAGLVNAGGIILTRFSPLFHGGIASIILLLLAGISVMIGT
                     GISLVQVDYKRQLVGSTIGQMGFMLIQCALGAYIAAIIHLILHGLFKATLFLQAGSAVG
                     RHEVSARTNERTSYLWVMAGRILSLVIGVAFWLAAPGEGYQFISALILGWSLSVSWTQL
                     VAFGEGRIGRIAGLTVLGGAALVYFIIHNLFYKWLHTTIFQSVQPPMSAVMIVVCLLLF
                     GSALGTWVARHRSSVFFAVLYLWLVRLGEAKPKSVESHPDYLKQYIS"
     CDS             2976..5591
                     /locus_tag="ctg3_27"
                     /transl_table=11
                     /translation="MGITSVLTKDNVKKIDTDIDVQERDLNVFITSASRVIAPLWPIST
                     FAARNPWMGLENQSFDQVASWLKNTRDVDIYPSASMIRSAKNKGEIDEDFVEMGLQRWL
                     DSHSYHIPRDVAERFCHAALKLDPLPSDLLSSHKLEKLVSECSGLDHIENVFMQPLSSH
                     IENQDGERLVNILDHHVIKWSKLYLDDSQAGWTMPNREEGFYRAWQHLIQYDPALSKKQ
                     RERVKGWPKEAHLALQKALFALEIPESEIQTYLEGHLLSLPGWAGMMLWRSQQSSHEHA
                     LLTEYLAVRISMEWALIKPYLSLTNERSKKKISIAPLIAAWIHWGGLTLEEWSQMTAVE
                     QNEYLSFAYSFDEKLRKKLWLEAWEQTYTDRLSQKIISKQRETGGKKSALAQLAFCIDV
                     RSEPFRRQLEKEGPFETIGIAGFFGVPIATCELGSKHSHASLPIIQKPQNKIKEFADED
                     VFKKYNQRKQAIYSLSHTFKTMKQNALSSLLLPELSGPWLTLQMAARSFVPRKAGRFIR
                     NLREAWLRKPDTKLSLHHDATEAEIPVGFTDEEKVNYARQALKMMGLTENIAPLVVICG
                     HGSQSTNNPYSAALDCGACGGAAGGFNARVLAALCNLSEVREALLAEGIKIPEDTVFAA
                     AEHNTTVDELHWLYVPELSEAAQEAFEQIEAVMPKVRHHVNAERLAQLPNFQSKLKNPK
                     AEANRFAEDWSEIRPEWGLARNAAFIIGKRELTQDCDLEGRAFLHNYDWKQDESGELLA
                     NIIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLAGLPWQS
                     VMESDHEAYHSPLRLLILIQAPREYVERLLNNDSAFLQKVQNGWVRLANIDPEGCWESW
                     "
     CDS             5668..6195
                     /locus_tag="ctg3_28"
                     /transl_table=11
                     /translation="MNVIQNKKVLFLTDIENGLEPILQEATNTSAENMLTIQSYGAGIS
                     HPYGEIMRSVIFAIYQEDVEEIFVVGTKDKKTSAGNGLTQLETMKDKIQTLDYLFQNCK
                     PEFLGGTVDEWLNENSSDTIEKSVDMIRHHPLVPSYVKVRGLFVHHKDGKPSIVEVPDV
                     KTGQALPDHCLS"
     CDS             6152..6262
                     /locus_tag="ctg3_29"
                     /transl_table=11
                     /translation="MLKQVKPYLIIACHDEIQVQLLNAPIYGESSSKEIV"
     CDS             6259..6549
                     /locus_tag="ctg3_30"
                     /transl_table=11
                     /translation="MSANLTDFVTKTIEDMNSFDRENMECMKKLIRKAIDFYHLKSYEE
                     VEETHSGNVRFLHVHSMMEENMLSKMIVVTRNGKTDLDIEGVYEGYVVREY"
     CDS             6607..6981
                     /locus_tag="ctg3_31"
                     /transl_table=11
                     /translation="MKKSKGSIESEISKSITKWEKDYLGRGSVSVKTDILRDMIIVNLK
                     GILTPAEYVVCGSKEGMLSIKQTRSELVESGIEGLKDIILKITGEKVKSFHTDLSSRTG
                     ERVMVFKLCNDLEKNLEKIL"
     CDS             7477..7779
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 67.7; E-value: 1.1e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg3_32"
                     /transl_table=11
                     /translation="MEPIEVFKALSNESRLQILQWLKEPDRHFAPHEGIDMNTIGVCVS
                     QITDKLKMTQSTASQYLTILLRAGLIKAERIGKYTYYKRDEEAIGKLADFLKTEI"
     CDS             7906..9078
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 337.1; E-value: 1.7e-102)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_33"
                     /transl_table=11
                     /translation="MSNTWKIYILAIVSFLVGTSEYIISGILDQIAHTLGITLAAAGQL
                     ITIFSLVYALSTPVLMALTASMDRRKLMMYALGLFVFGNVLAFVLPGYGWFIAARIIMA
                     MGAGVVVVTALTIAAKIASEGKQGSAIATVVMGFTASLIIGVPLGRMIAVALGWKSVFG
                     AIALLGLIAMVVIFFTLPHTEGDKPVPLLQQLALFKKRKVAMGLSITFFWLGGYSVAYT
                     YLSPYLLNISGINGKLLSGVLLIFGIASLVGSKFGGYSTDKWGVPFTLVGGMTLHIVTL
                     ILLSLVTHSYIGVLVILILWSFAAWSTGPTQQFHLATIEPEMSGVLLSMNQSMMQFAMA
                     VGAGIGGVFVENVSLTSITWVGALGVMIAIITSLMIFNSQPKQALKDINQ"
     CDS             10001..10168
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: TIGR04404"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_34"
                     /sec_met_domain="TIGR04404 (E-value: 1.1e-38, bitscore:
                     123.7, seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRNQKEWESVSKKGLMKPGGTSIVKAAGCMGCWASKSIAMTRVC
                     ALPHPAMRAI"
     CDS             10235..11467
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_35"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     6.5e-16, bitscore: 51.4, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 6.9e-23, bitscore: 74.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.2e-07, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.3e-06, bitscore: 21.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAF
                     LLSKNKNLHKTARIWEIMKKEEMSADQLKEELSAHPFTEAWTEGLLDQPLHVSGSLDSY
                     LPISCTLQLTNACNLSCSFCYASSGKPYPEELSSEQWILVMQKLAAHGVADITLTGGEA
                     KLIKGFKELVVVASSLFTNVNVFSNGLNWRDEEVELLSHLGNVSVQISIDGMDNTHDQL
                     RGRKGGFKESMNTIKKLSEANIPVIVAMTINESNADEVSDVVEQCANAGAFIFRAGKTL
                     SVGRATEGFKALDIDFEEMVQIQLREARHKWGDRLNIIDWEHEESSFTTDFCTPGYLAW
                     YIRADGYVTPCQLEDLPLGHILEDSMADIGSPARLLQLKCEAKNCKCIGKIELSEPDLP
                     FQKEVKAGIQE"
     CDS             11464..12954
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: skfc"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_36"
                     /sec_met_domain="skfc (E-value: 4.9e-290, bitscore: 955.3,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Abi (E-value: 2.4e-14, bitscore: 46.4,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSLSLVFWSILAVVGLLLFIKFKPPTIASLLLSKDEAKEISIQF
                     IKEFVGIDVENWDFYSVYWYDHDTVNKLHHLGILKKNRKVLYDVGLVESWRVRFVHQNQ
                     SFVVGVNANREITFFYADVPKKTLSGKFEQVSPETLKQRLMASPDGLWSRANMTGTGKK
                     EEDFREVSTYWYIAEAGDIRLKVTVELQGGRISYIGTEQEILTDQMSKVIRDEQVESTF
                     GVSGMLGSALAMILAILILVFMDVQTSIIFSLVLGLLIIICQSLTLKEDIQLTIVNAYD
                     ARMSVKTVSLLGILSTLLTGLLTGFVVFICSLAGNALAGDFGWKTFEQPIVQIFYGIGA
                     GLISLGVTSLLFNLLEKKQYLRISPELSNRTVFLSGFTFRQGLNMSIQSSIGEEVIYRL
                     LMIPVIWWMSGNILISIIVSSFLWAVMHQVTGYDPRWIRWLHLFIFGCFLGVLFIKFGF
                     ICVLVAHFIHNLVLVCMPLWQFKLQKHMHHDQPKHTSL"
     CDS             12973..13692
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 178.6; E-value:
                     2.5e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_37"
                     /transl_table=11
                     /translation="MQLMQVQNLSKCYRNGDGVEHLSFSIQRGEIVALLGPNGAGKTTT
                     IRCLTGLYKPDKGDILIEGSPPGDINVQKKVALIPDQPYLYPALTAAEHIQFRARGYHP
                     GKKDVKERVYHALKEVHLEEKANQLCGQLSRGQKQRVVLAGAIVQDALLYILDEPTVGL
                     DIPSKQWLSNWLKTKTDQGCSAFVSTHSLEFVIETADRVILIRDGKLMQDLYVPQFEEQ
                     AEWRKEVIRLLGEWSDE"
     CDS             13685..15100
                     /locus_tag="ctg3_38"
                     /transl_table=11
                     /translation="MNNIISFLWLQSKRRFVSQGQEKKMPFLIMLLFVGAIGFQVSFVS
                     RSTTWDMSIAGWVLTGVFILYTAFGLFSNRLPSQMADIIWLYGTATSFSKVVYSVLFFS
                     VTWKALLWIISAIFGDVLIVLLSGDHINLLGRSIIFVGLFFIAEVWLMSVSCARTVKKM
                     KRVYVLVFLLMLGIYSICLYRFFFLQHSSGIWESIARFISGVGLVFDTLSPLYVVVFIG
                     IITVSFMTIAFTSRQVEMKESLVKEAEFWEEFQERQFGSGQIIQKPKTTWWGLQGLNGI
                     WSFLWLELLLFKKYLFFHSIHTVMLSGVFYVVIFMYPEWFYLLFFLIVSAVMLSSYYSG
                     IVRHSQSGTLHLFPGALWKKIIILELTNTVWLYILYCVSITFMAVGNLVYWYIYGLGIY
                     IWFMTIRLFAFTHTNRNDIKLSLPQYYKSFFMALGLSGICLYVIHLLTADWYTLVVVVC
                     IGSLSWCLFYRFR"
     CDS             15147..15662
                     /locus_tag="ctg3_39"
                     /transl_table=11
                     /translation="MNSNGDKLSLSVQNLANTNEITIVQAIGELKKSGKDAIPVLVEAL
                     KEEGSLCNIAAAVLGEFGEDASEAAEELSCLLKSHAEDTRMAAAISLMRIGKPSLPFVI
                     KIAQESEGQSCFWASWCIAWIDPSCIEPKMYKCLKYEHEHPSGIVAPFAAEEALGKLIA
                     FQLKDKED"
     CDS             15667..16092
                     /locus_tag="ctg3_40"
                     /transl_table=11
                     /translation="MKDEQMLTEWPSHLPWLNQSQNDFTFPSDTYLLLYFWSMSCPNCH
                     QLTDKVLQDIKDMNVKVIGVHVPYIEEEKSMEVVLTYALDRGLAIQIVLDQNYEIVTTC
                     HVQGIPSFCLLSQYGQIITKTMGDVGWDKMLKKIAGL"
     CDS             16341..17318
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_41"
                     /sec_met_domain="PF00561 (E-value: 1.4e-08, bitscore: 27.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLWKVLKIVFVSLAALVLLVSVSVFIYHHFQLNKEAALLKGKG
                     TVVDVDGKKMNVYQEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVDRAGYG
                     YSEVSHDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAMYWAQKYPKEIKAIIA
                     MDIGLPQQYVTYKLSGVDRLKVRGFHLLTSIGFHRFMPSAVYNPEVIRQSFLTDEEKEI
                     YKAINFKQFFNADMEHELLQSYQNGSKSVNLPAPKETPVLILDAVSDQNRHSKYAIQNR
                     KDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKLSMEFMRKVR"
     CDS             17320..17991
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 126.9; E-value: 1.4e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg3_42"
                     /transl_table=11
                     /translation="MKGYHILIVEDDVMIGDLLQKILQREGYRVIWKTDGADVLSVIQK
                     VDLVIMDVMLPGEDGYQMSAKIKKLGLGIPVIFLSARNDMDSKLQGLQIGEDYMVKPFD
                     PRELLLRMRNMLEHHYGTFTQIKHLYIDAVTKKVFNESLHDEVLFTAIERKIFFYLYEN
                     RDSILTKEHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEMIENIYGEGYRLNTVVK
                     K"
     CDS             17988..18974
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 59.4; E-value: 5.8e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg3_43"
                     /transl_table=11
                     /translation="MKLKTKYQLLLFTAVISVPMLLLAVSVLMSVIYDSMFKPMNHGMP
                     FHRSFAYPAMIVVFLISLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQRVPDKIEVK
                     RADEIGELIKSVNLLIERTTYRELELRQQEEIKKELLQKLRHDINTPLTALRLQLFYLE
                     DQCHGQAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMSGIELHYKAADQDVIWMSNALWMQRLFDNIFQNTLKHSKAEKMEVTIEHDNVFIR
                     DDGIGFDRNESSEGLGLKIIEDTCRLLAITYELHTNDSGTGFLFSKE"
     CDS             19093..19284
                     /locus_tag="ctg3_44"
                     /transl_table=11
                     /translation="MTDIADTGITAAAGADIIAATAARAKEDTTTVMAAVIVTNAGATA
                     AVNPKKFLFRFWDKGFFM"
     CDS             complement(19277..20047)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 111.8;
                     E-value: 6.8e-34)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg3_45"
                     /sec_met_domain="Pkinase (E-value: 1.2e-33, bitscore:
                     109.4, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKLLKKLLFDRPLKNGVILNHQYKIEECLGMGGYGLVYLCTDI
                     LTQTPYVLKQLRPTKAKKEKEKVRFQQEIKLLNSIHHPQIPGFIDEFIIDGQAYYVMQF
                     IEGENIEELLFFRKQPFTELMALQLISQLLEIIEYLHDRLIFHSDIRTPNIIINDGRLC
                     LIDFGLAKQLTPEEMEEIKVRKQDDFFDLGETLLFLLYSQYKGKKKKNGTWLEELTLTK
                     EVTLLLKRLLGIEEEYQHTASIREDLNRAIQSVT"
     CDS             complement(20133..20990)
                     /locus_tag="ctg3_46"
                     /transl_table=11
                     /translation="MVKKWLIPFAVMLSVLFTFTYSASAAGVTAITGNNSFDTAMPIGY
                     WKYKNIDTTILEAGQDEAYFTFTANKGEKVYVRSTYQSAYTGMKIEIYDKNRIPVSQGT
                     EVINPNTFSSFIYANADAQNTTDTFYVKVSRGTYTGNMYFTLSIEDRIKSGSGTFQFSG
                     VAENKGNTSLSPSGSDSSVIKVDLTNQSGIPRDAIVTRVQTTATQTPSQGNTRHLIMTS
                     ENNEWRRALVNSSTSGSYDISLSDQLSVAKVWSFKYNTLATARSTMSNVKAKIDYEYDV
                     TKQF"
     CDS             21122..22306
                     /locus_tag="ctg3_47"
                     /transl_table=11
                     /translation="MRLNRQFIRTQLMAQNILSKNAPAKRENATENPAAVLEKAYSRLK
                     SQSSTGGINQFNYSKTSVSGNSGAFSKVYQSANDRTVTDTGEETVIQSQNPYESESDIR
                     IKILDEKYSRMNAINKTKSDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEWLFK
                     GKAQNYNLQDAVFRNVTFHGEVEAENEKVYQRGQVNQQLQVLLNRNHIHIPEGTELTFT
                     ITPIDYQVRVSGSDDQDLIKQIEQVLQSGDNSKELFLHIMKSQSSDSAQFSEEAYQKYQ
                     AAREMYEVTGYHLKDLEVIDGRYVTPEGRDLMDVYKEELEKDPVQKQTASYAISYYRSE
                     LSKIAEAGYNAIPDFILSIDYSNGSLRDVGQSKSYGTGDTGWLEALKRQTGVNY"
ORIGIN
        1 ctctccgcgc aaattttcgc ccttgtaaac gttgcaagcc cactaatgaa aaaatgcctg
       61 atagcgagtg ggttgattta attactgaat acattgataa aaatttcaca gaaaaattaa
      121 cgctagaatc gttagcagat atttgtcatg ggagtccgta tcatatgcat cgaacattta
      181 aaaagattaa aggcattacg ctggttgagt atatacaaca agttagagta cacgcggcta
      241 aaaagtattt gattcagaca aataaatcga ttggagatat cgctatatgt gtgggtatag
      301 ctaacgcgcc ttattttatt actttattta aaaagaaaac tggacagaca ccagcacaat
      361 ttcgtcaaat gagtaaaatg gaggaaacgt acaatggaaa caaataaacc aaccctttat
      421 tggtctttac taatgttcaa ggattggaat ttttatattg cttcaacttt aaaggggctt
      481 gtgtttgtag gttcacagaa caaaccaatc gaggaattgt tcgaatgggc taggaaacgc
      541 tttccgggaa gtcttcttgt tgaagatgat gataagcttg aaccctatgc cgttgaaatc
      601 actcaatatc tagaaggaaa gcggaaaaac tttactgttc cagttgagta cgccggtacg
      661 caatttcagc tagcagtctg gaatgcactt tgtgaaattc cttatggaca gacgaaatcc
      721 tattccgaca ttgcaaatga aataaataaa ccagcagctg ttcgtgctgt aggtgcggct
      781 attggggcta atccggtatt aattactgta ccgtgccatc gtgtaatagg gaagaatggc
      841 tcattaactg gctatcgggg cggattcgaa atgaagacac tgctcctcga tctggaaaag
      901 cgagcttcat ctgaaatgga tgttcctcat tgaaagtgaa tcatctataa tgggttggat
      961 tcttttagag gaaagtaaag accagtttac tgataaactt gacaactttt aaaatttagc
     1021 atatcttata cgtaacttaa taatcgatgc agatgtttat ttttcctttt aaaatatgta
     1081 ggcctttagc attcttttca tatttaattt taaatattga taggatgaaa aagtatccta
     1141 ataaaaaagg aagagaacat gagtcgattt atttgataat caggactata ttaaaggaaa
     1201 tgaaaacata gcataaagta taataaggta gctcttcaaa aaacttcgct gaagttagtt
     1261 gaagtgaagc cgacaatttt caggattcaa tgatctaaca taatcattga aattttgaag
     1321 ttgtcggctt ttttgttgga aaaaaataga gataaataaa aattgaaata aataatagac
     1381 aaatatgatc tgattgaaag atcttttgac caataatgag ttttaaaaaa gggagaattt
     1441 agaatgttag tttcgctgag tttgtcatca ttattaacat tattttttat tatgcttatg
     1501 gcttctggga ttagtggact attgttttta catccgcgag tacccttgag ttttgttcgc
     1561 attcatattg ggatcttggc tttaccactt ttggtttcct tactgattct tgccgatagt
     1621 ggtgtgagcg gaaatgttgg cccttggcac ttagattcct tagcttgttt aatgactttc
     1681 tttgttcttg caattggatt catcattcag cgtttttctt tacgttactt aatgggggat
     1741 cgatcttatc gaaaatattt tacgcttttt actttcacaa caggtgctgc ttcaatgaca
     1801 tggttaagtg gcgatctccg cttgatgctt ctattttggg gagcaactct tgttggttta
     1861 accttactta ttaggttaaa cagtgcttgg caagtggcta gtgaagcagc caaggtttct
     1921 ggccgcttat ttttgttaag ttggttttct ttgttttttg cgatgatgtg gctttttcat
     1981 gccacaggtc aatggcagtt atcattggtt gtaacaaatg aaagtttagc tgggctggga
     2041 gaatgggaga gaacagggat tcagctattg attgtactgg cggtgatcat tcctgcagct
     2101 caatggccat tccaaagatg gttggttgag tctattgttg ctccaacccc tgtttctgca
     2161 attatgcatg caggtttagt aaatgctgga ggaataatac taactcgatt ttcacctcta
     2221 tttcatggtg gtatcgcttc gattatctta cttctgcttg ctggcatttc tgtaatgatt
     2281 ggaactggaa ttagtttagt ccaggttgat tataaacgcc agttagtagg ctccacgatt
     2341 ggacaaatgg ggtttatgct cattcagtgt gcattaggcg cctatatagc agccattatt
     2401 catcttattt tacatggttt attcaaagct acgttgtttc tacaagctgg ttcagcagta
     2461 gggcgtcatg aagtatcggc tcgcactaat gaaagaacat cctatttatg ggtcatggct
     2521 ggtcggattt tatccttagt aataggcgtt gctttttggc tcgctgctcc tggagaggga
     2581 tatcaattca ttagtgcgct gatcttaggg tggtcattgt ccgtttcttg gactcagctt
     2641 gtcgcttttg gagagggccg aattggccga attgccggct taactgtttt aggaggagca
     2701 gccctcgtat attttattat tcataacctt ttctataagt ggctgcatac aaccattttt
     2761 caaagtgttc aacctccaat gtcagctgtc atgattgtcg tatgtctctt actctttggc
     2821 agtgctttag gtacgtgggt tgctcgtcat cgttcttccg tttttttcgc ggtactctat
     2881 ctttggttag tccgattagg tgaagcaaaa ccaaagtcag tagagagtca cccagactac
     2941 cttaaacaat atatttcata aggagctaat ctgagatggg cattacatcc gtattaacga
     3001 aagataatgt aaaaaagata gatacagata ttgatgttca agaaagggat cttaacgtat
     3061 tcattacatc tgccagccga gtgattgcgc cactttggcc tatttctaca tttgctgcac
     3121 gtaatccgtg gatgggactt gaaaaccaat cttttgatca ggttgcaagt tggttgaaaa
     3181 acactcgtga tgttgatata taccctagtg cgtctatgat ccgttcagca aagaataaag
     3241 gtgagattga tgaagatttt gtggaaatgg ggctgcagcg ttggcttgat tcacattcct
     3301 atcacatccc acgggacgtg gcagagcgat tttgtcatgc tgcattaaag ttagatcctc
     3361 tgccttccga ccttttatca tcacataagc tggagaaatt agtaagtgaa tgtagtggat
     3421 tggatcatat cgagaatgtg tttatgcagc cactaagttc gcatatagag aatcaagatg
     3481 gtgaaaggct agtcaatata ttagatcatc atgtcattaa gtggagtaaa ttatatcttg
     3541 atgactctca agcaggctgg acaatgccta atcgtgagga aggtttctat cgtgcttggc
     3601 agcatctcat tcaatatgat ccagcactta gcaaaaagca gcgagaaagg gtaaagggtt
     3661 ggccgaaaga ggcacatttg gctttacaga aagctttatt cgcactagaa atcccagagt
     3721 cagaaatcca gacttatctt gaaggtcatt tactttcatt acctggatgg gcagggatga
     3781 tgctttggcg ctcccagcaa tcgagccacg aacatgcact cctaacagaa tatttagcgg
     3841 ttcgaatatc catggagtgg gctcttataa agccatactt atctttgact aatgaacgat
     3901 ctaagaaaaa aatttcaatt gctcccctta tagcagcttg gattcattgg ggtgggctta
     3961 cattagaaga atggtcacag atgacggccg ttgaacaaaa cgaatattta tcatttgcct
     4021 acagctttga tgagaaactt cgcaagaaac tttggttaga agcttgggag caaacgtaca
     4081 ctgatcgatt aagccagaag atcatctcga aacaacgtga aaccggcggt aaaaaatctg
     4141 cattagctca attagcattc tgcatcgatg tacgatcaga accttttcgt cgtcaactag
     4201 aaaaagaagg cccgtttgaa acgattggta ttgctggttt cttcggggtg ccgattgcaa
     4261 cttgtgaact tggcagtaaa cacagtcatg cttccttgcc gatcatacaa aaaccgcaaa
     4321 ataaaataaa agagttcgca gatgaggatg tattcaaaaa atacaatcaa cggaagcaag
     4381 caatttattc tttaagccat acctttaaaa cgatgaagca gaatgcgctt tcgagcttac
     4441 tactgcctga gctaagcgga ccttggctta ctctgcaaat ggcagcccgt agctttgtgc
     4501 caagaaaggc gggtcgtttc attcgtaatc tccgtgaggc ttggttacgc aaacctgata
     4561 caaaactctc gcttcatcat gatgctacag aggcagaaat acctgtgggt tttactgatg
     4621 aagaaaaagt gaactatgct cgccaagcat taaaaatgat ggggttaaca gagaacatcg
     4681 caccattggt cgtaatttgc gggcatggca gtcaaagcac taataatcct tattctgcag
     4741 cccttgattg tggtgcctgc ggtggagcgg ccggtggatt caatgcaaga gttttagctg
     4801 ctttatgtaa tctatcagag gtacgagaag ctcttttagc tgaaggaatt aaaattcctg
     4861 aggatacggt ttttgcagca gctgaacata atacaacagt agatgaatta cattggcttt
     4921 atgtaccaga gctttccgaa gctgcacaag aagcatttga acaaattgaa gccgttatgc
     4981 cgaaagtgag acatcatgta aacgcagaac gtctagccca attaccgaat ttccaatcga
     5041 agctaaaaaa tccgaaggct gaggcaaacc gatttgcgga agattggagt gagatacgtc
     5101 cggaatgggg actggctcgt aatgccgctt ttattatcgg taaacgtgaa ctaactcagg
     5161 attgtgattt ggaaggcaga gcctttctcc ataattatga ttggaagcag gatgaaagcg
     5221 gtgaactcct agcaaatatt attgcaggac ctggaactgt agcccaatgg attaatttac
     5281 aatattacgc atcaacggta gcacctcatt attatggcag cggaaataaa gcaactcaaa
     5341 ccgttactgc aggtctcggc gttatgcagg ggaatgcaag cgatttgtta gccggactgc
     5401 cttggcaatc cgtcatggaa tcagatcacg aggcctatca ttctcctctt cgtttattga
     5461 tactcatcca agcacctaga gaatatgtag aacggttatt aaataatgat tcagcatttc
     5521 tgcaaaaagt tcaaaatgga tgggtccgac tggctaatat tgatccagaa ggatgttggg
     5581 aaagctggta atgatgaatg taagcattta tcaaatggat ttgttattca aaataagaat
     5641 gataaacata gggaagaggt gtgctgtatg aatgtaatcc aaaataaaaa agtattgttt
     5701 ttgacggata ttgaaaacgg tttggagcct attttacaag aagcgactaa cacttctgca
     5761 gagaatatgt tgactataca aagctatggt gccggtattt cacatcctta tggagaaatc
     5821 atgaggtctg ttatttttgc gatttaccag gaagatgttg aggagatttt tgtagtagga
     5881 acaaaagaca agaagacttc cgcaggtaat ggactaactc aacttgaaac aatgaaagat
     5941 aaaatacaaa cattggatta tctctttcaa aattgcaagc ctgaattttt aggtggtacg
     6001 gtcgatgaat ggctaaatga aaatagcagt gacaccattg aaaaaagtgt tgatatgatt
     6061 cgacatcatc ccctagtgcc gtcatatgtt aaagttagag gtttattcgt tcatcataag
     6121 gatggaaaac cctcaatcgt ggaggttcct gatgttaaaa caggtcaagc cttacctgat
     6181 cattgcttgt catgatgaaa tacaggttca acttctaaac gcacccatat atggagaaag
     6241 cagttctaag gagattgtat gagcgctaat ttaactgatt ttgtcacgaa aacaatagag
     6301 gacatgaact cgtttgatcg tgaaaatatg gaatgtatga aaaaactaat tagaaaagca
     6361 attgattttt atcatctaaa gtcttatgaa gaagttgagg aaacccattc aggaaatgtt
     6421 cgatttttgc atgtccactc tatgatggaa gaaaatatgt tatccaaaat gatagtggtc
     6481 acaagaaacg gtaaaactga tttggatatt gaaggtgtat atgaaggata tgttgtaaga
     6541 gaatattaat gagacgaaat cacaaataga atatgccaat ttttttgctc aggagatgta
     6601 ttagatatga aaaagtcgaa gggttctatt gaatcagaga tcagtaagtc cattactaaa
     6661 tgggagaagg attatcttgg gcgggggtct gtatctgtta agactgatat actgcgggac
     6721 atgatcatcg tcaatttaaa agggatttta acaccggccg aatatgtagt ttgtggatca
     6781 aaagagggta tgttatctat caaacaaact cgttcggagt tagtcgaatc aggtatagaa
     6841 ggccttaagg atattatctt aaaaataacc ggagaaaaag tgaaaagttt tcatactgat
     6901 ttaagctccc ggacaggtga acgagtgatg gtgtttaaat tatgtaatga tctagagaaa
     6961 aatttggaaa agatcttata atctaaagaa aataaatgtt ttgacggtat ggaatctgtt
     7021 gtgaattgaa cataatgaac tgccgcttct tttgttttac aattatggca tcattgataa
     7081 cttttattca taacctaagc ggacataaag agatgtcaat tcatagtaca ctgacttgtt
     7141 attcctgtcg aaagatctaa catccgctgt tgttatgagc ggatgttttt ttacatctat
     7201 tttaaataca tgaatttgat gctggtgatt agtcacttga acaatattaa attcatttta
     7261 attgaaaaca tccttgtcac ctgccgggtt ccccaagtgt ttagtgacat gattatgaga
     7321 ccaatttcgt aaagcttgat gataaattta agaggtgaac aaaattgata tgctgtcttc
     7381 agtttcattt cacggaatta gtcatagata aacctttaat taaatatatc caaaaaacgg
     7441 attgacatat cgaaatataa cgatataata atcgatatgg aaccaattga agtattcaaa
     7501 gccttatcaa atgaatcaag gctgcaaatt ttacaatggc tgaaggagcc cgatcgtcat
     7561 tttgcacccc atgaagggat tgatatgaac acaatcgggg tatgtgtcag tcaaataaca
     7621 gacaaattga aaatgacgca atcgacagct tctcaatatc ttaccatcct tttaagagcc
     7681 ggcttgatta aggcggagcg tattggaaag tacacatatt acaaaagaga tgaagaagcc
     7741 attgggaaac ttgctgactt tcttaaaaca gagatataaa aataaacatc aaaagatgtt
     7801 tatttttaca ccatacatat cgacatatta cgatgtgttt attttttata ataacatatc
     7861 gataattcgt gatatgttta ttgataatta aggagtgaat gttttatgtc taacacttgg
     7921 aaaatttata ttttagccat tgtcagcttt ttagttggaa cctcagagta catcatttcg
     7981 ggaattttgg atcaaattgc tcatactctc gggatcactt tagctgccgc gggccagctt
     8041 attaccattt tctcacttgt atatgctctt tctacacccg tacttatggc gttgacagca
     8101 agtatggata gacgcaaatt gatgatgtat gccctaggtt tgtttgtgtt cggtaatgtc
     8161 ctggcttttg tactgcctgg ttatggatgg tttattgcag cgcggatcat tatggcgatg
     8221 ggagcaggtg tggttgttgt caccgcatta acgattgccg ctaagattgc atcggaagga
     8281 aagcagggaa gtgccatcgc tacggtcgtg atgggattta ccgcttcttt aatcattggt
     8341 gttccgcttg gaagaatgat agcagtagca ttaggctgga agtctgtatt tggagcaatt
     8401 gctttgttgg gattgatcgc aatggtcgtt attttcttta ctcttccgca tactgaaggg
     8461 gataagcctg tgcctttgct tcaacagctt gctcttttca aaaaacggaa agtggctatg
     8521 ggattatcaa tcactttctt ctggctcggg ggatattctg ttgcttacac ttatttgtca
     8581 ccgtatctct tgaacatctc aggtataaat ggcaagctgc tcagtggtgt tttgcttata
     8641 tttggaattg ccagtttggt tggatcaaag tttgggggat atagcaccga taaatgggga
     8701 gtgcctttta cactcgttgg cgggatgacg ttgcatatcg tcacactgat tcttctgtca
     8761 cttgttactc attcctatat cggagtgttg gtgattctca tattatggtc gtttgccgca
     8821 tggtccaccg gtccgacaca gcaatttcac ctggctacaa tagaaccgga aatgtcaggt
     8881 gttttgctta gcatgaatca gtcaatgatg caattcgcca tggcggtcgg cgcaggtata
     8941 ggaggagttt ttgtggaaaa cgtatcattg acctcgatta cctgggttgg tgcgttaggg
     9001 gttatgattg caattattac atcattgatg attttcaatt cgcaaccgaa acaagcgcta
     9061 aaagatatca atcaataatt tcgaaaaatc taacatccgc tcgttataca agcgggtgtt
     9121 ttttataagc attcaaagtc agtccatgca tgagccttcc aagggccgac atcgttctgt
     9181 atgtgtcgaa ggcgcactga agctgaaagg gatttcttaa ggcttttccg ctgaagtacg
     9241 gtacgattgc cttgatcgaa cactggaaac acaagagaac gtaaacctga acattcgcgt
     9301 aaacgtcaag gaagttgcca cttggggagt aaacacttgc atcatctcgc tgaaaggcct
     9361 agacaatgcg gatgacatat tcgtattgcc ggaagtaaac acagcgcttg ctctgtttcc
     9421 gttggtttct gttgtcggtt gcagctgatt gcttactaat gatgccctgc atctcggttg
     9481 tgatgtcgat aagcagcgta accttgtgaa gagtgttact gtggagtaag atgtttaacc
     9541 cctttggata ttttagccga aggggttttt agtatagata tttgatttaa attacaggag
     9601 acttcattca tttaactaaa gtcattgctt tcttaatcac taaagtttat ttgaaaataa
     9661 tctcttgatt tattttcctc gaagagattg tttgtcaatc tattaggcat cagaattttt
     9721 ataacagaat ggatcgtctt tttgacgttt tgtttataga acaagaaaat attcaaaaca
     9781 taagtgaaaa attaggggtg agctcctgtt tttctcgaga ggatagcttg tcagcttttc
     9841 tatttttaaa gggttaaaat attctattta tactaattaa tgtaattttt aggataatat
     9901 acaaaatccc ccttacttcg acaattgcaa tctggtatta tcgtatcgca tgggagctat
     9961 gtcaatagac tctatgcaaa aattgagagg aggtttactt atgaaaagaa accaaaaaga
    10021 atgggaatct gtgagtaaaa aaggacttat gaagccggga ggtacttcga ttgtgaaagc
    10081 tgctggctgc atgggctgtt gggcctcgaa gagtattgct atgacacgtg tttgtgcact
    10141 tccgcatcct gctatgagag ctatttaaca tttgagaata gggagttgag cgtatttgct
    10201 tatactcctt attttctctt aagggggatt ttatatgtca tatgatcgtg ttaaagattt
    10261 tgatttgcca gagttagcgg ttcatttaca gcctcatggt gctgtaatga ttgatagaaa
    10321 aagtatgttt tatttcagac tcagtggacg tggagcacag ttggcgtttc tgttatcaaa
    10381 aaacaaaaat cttcataaaa cggcacgtat ttgggagatt atgaaaaaag aagagatgag
    10441 tgctgaccaa ttaaaagaag agcttagtgc ccatccattt acggaggctt ggacggaagg
    10501 gctgttagat cagcctttac acgtttcggg ttcgctagat tcatatttac ctattagttg
    10561 taccttacag ttgacaaatg cttgtaattt aagctgttcg ttttgctatg ccagctcagg
    10621 taaaccatat cctgaggaat tatctagtga acaatggata ttggttatgc aaaagctagc
    10681 agcccatgga gttgctgata ttacgctgac cgggggtgaa gcaaagctga tcaaagggtt
    10741 taaagaatta gtcgttgttg caagttcgtt gtttaccaat gtgaatgtat ttagtaatgg
    10801 attgaactgg cgagatgaag aagttgaatt acttagtcac ttaggcaatg tttctgtaca
    10861 gattagtatt gatggtatgg ataatacaca tgaccaatta agaggcagaa aaggcggctt
    10921 taaagaaagt atgaatacca ttaaaaaatt atcagaagca aacattccag tgattgtcgc
    10981 tatgaccatt aatgagtcca atgctgatga agtatcagat gtggtggagc aatgtgccaa
    11041 tgcgggtgct tttatctttc gtgcaggaaa aacgttatct gttggacgtg cgacagaagg
    11101 ctttaaggct ttggatattg attttgaaga aatggttcaa atacagctta gggaagcacg
    11161 tcataaatgg ggagatcgcc tgaacataat tgattgggag cacgaagaga gttcgttcac
    11221 aacagatttt tgtacaccag gatatcttgc ttggtatata agagcagatg gatacgtaac
    11281 tccttgccaa ttagaagatt tgccgctagg gcatatttta gaagatagca tggctgacat
    11341 tggttcacct gctcgtttgc ttcagttaaa atgtgaagca aaaaattgca aatgtatagg
    11401 gaaaattgag ctatctgaac cggacttacc ttttcaaaaa gaagtcaagg cagggattca
    11461 ggaatgaata gtctatcatt ggtgttctgg agtattttag cagttgttgg attactgtta
    11521 tttattaaat tcaaaccccc aacaattgct tcactactct taagcaaaga tgaggcaaaa
    11581 gaaataagca ttcaatttat aaaagagttt gttgggatag atgtagagaa ctgggatttt
    11641 tattcagtat attggtatga ccacgataca gtaaataaac ttcatcactt aggcatactt
    11701 aagaaaaata gaaaggtttt atatgatgtt gggttggtcg aatcatggag agtccgtttc
    11761 gttcaccaga atcaatcatt tgtagttggt gtcaatgcca atcgagaaat cacttttttt
    11821 tatgcggatg ttccgaaaaa aaccctttcg gggaagtttg aacaagtttc tccagagaca
    11881 ctcaagcaga ggttaatggc ttcacctgat ggactttggt ctagagcaaa tatgactggt
    11941 actggtaaaa aagaggagga ttttcgcgag gtcagtactt attggtacat agcggaagcg
    12001 ggagatattc ggctcaaagt gactgttgaa ttacagggcg gccgaatttc ttatattggt
    12061 actgaacaag aaatactaac agatcaaatg agtaaagtca ttcgagatga acaagtggaa
    12121 tcgacattcg gagtatctgg tatgctgggt tcagctttag cgatgatcct tgcgattctc
    12181 atccttgtat ttatggatgt gcaaacaagc ataatcttca gtcttgttct gggtttgttg
    12241 attataatat gccagtcatt gacgctgaaa gaagatattc aattaacaat tgtaaatgct
    12301 tatgatgcaa gaatgagtgt caaaacggtc agtttattag gtattttgtc tacacttctt
    12361 acaggattat taacaggatt tgtagtattt atatgttcat tggcaggaaa tgcgcttgct
    12421 ggtgattttg gatggaaaac gtttgaacaa ccaatagttc agattttcta tggaatagga
    12481 gcagggctca ttagtttagg agtgacttct ctgctgttta acttattgga gaaaaagcaa
    12541 tatttacgaa tttcacctga gctttctaac cgaactgtct ttctatcagg ttttaccttt
    12601 aggcaaggat tgaatatgag catacaaagt tcaattggag aagaggtcat ctatcggcta
    12661 ttaatgattc cagtcatttg gtggatgagt ggaaatatcc tcatctccat tattgtatct
    12721 tcctttttat gggcggtgat gcaccaagta actggatatg acccaaggtg gatacgttgg
    12781 ctgcatctat ttatattcgg ttgctttctg ggagttctct tcatcaaatt tggttttatt
    12841 tgtgtattag tagctcattt cattcataat ttagtactcg tctgtatgcc gctgtggcag
    12901 ttcaagcttc agaaacatat gcatcatgat cagccaaagc atacttcact ctaatgatta
    12961 ggagaagatt tgatgcaatt gatgcaagta caaaatttaa gcaaatgcta tcgaaatggt
    13021 gatggggttg aacatttgtc tttctcaatt caacgaggag aaatcgtggc gctattgggg
    13081 ccaaatggag ctggaaaaac aacgacaatt cgatgtttga caggtctcta taagccggat
    13141 aaaggagata tcctcattga gggttctcct ccaggagata taaatgttca aaaaaaagtc
    13201 gcgcttattc ctgatcagcc atatttgtat cccgctttaa ctgctgctga acatattcag
    13261 tttagggcaa gaggatatca tccaggtaaa aaagatgtaa aagaaagggt ttatcatgca
    13321 ttgaaggaag tgcacttgga ggagaaagca aaccaattgt gtggtcagct gtcaagaggc
    13381 caaaagcagc gggttgtcct ggcgggggcg attgttcaag acgctttgct gtatatatta
    13441 gacgaaccga ctgtgggcct tgatatccca tcaaaacagt ggctctctaa ctggttaaaa
    13501 actaaaaccg atcaagggtg ttcagcattt gtatcaactc atagtctaga gtttgttata
    13561 gagacagcag acagggtgat attaattaga gacggcaaac tcatgcagga tttgtatgtt
    13621 cctcaattcg aagaacaagc ggaatggaga aaagaagtga ttcgtcttct aggggaatgg
    13681 tcagatgaat aatatcattt cttttttatg gcttcagtca aaaaggcgtt ttgtaagtca
    13741 aggtcaggaa aaaaaaatgc cttttttgat catgctcctt tttgttgggg ccatcggatt
    13801 tcaagtaagt tttgtttcta gatctacgac atgggatatg agtattgctg gttgggtact
    13861 tacaggtgtt tttatccttt atacggcatt tggacttttt tcaaatcgat taccaagtca
    13921 aatggcagat attatatggc tttatggcac tgccacatct ttttcaaaag ttgtgtatag
    13981 tgttttattt ttcagcgtca cttggaaggc gttgctttgg atcatctcag ccatattcgg
    14041 tgatgtatta attgtgcttc tgtctggtga tcatatcaat ttattaggcc gatccataat
    14101 ttttgtaggg ctctttttta tcgctgaagt gtggttgatg tcggtctctt gtgccagaac
    14161 agtgaagaaa atgaaaaggg tatacgtttt agtctttctt ctaatgttag gcatttactc
    14221 catatgtctt tatcgcttct tctttctcca acattcatct gggatatggg agagcattgc
    14281 ccgttttatt agtggcgttg gattagtgtt tgatacattg tcaccgttgt atgtggttgt
    14341 atttattggg attatcacag tctcttttat gacaattgct tttacgagcc gtcaggtaga
    14401 aatgaaggaa tcgttggtga aagaagctga attctgggag gaatttcaag aacgtcaatt
    14461 tggttcaggt caaattatac agaaaccaaa aacgacttgg tggggcttgc aaggtctaaa
    14521 tggcatttgg tcttttctgt ggttggaact gttgcttttt aaaaaatatt tattttttca
    14581 tagcattcat acggtcatgc tcagtggcgt cttttatgtc gtcattttca tgtatccaga
    14641 atggttttat cttcttttct ttcttatcgt ctcggcagtc atgttaagtt cctattattc
    14701 aggaattgtc agacattctc aatcaggcac ccttcattta ttccccggtg ccctttggaa
    14761 aaaaatcatt attctagagc tgacgaatac agtctggttg tatattcttt actgtgtttc
    14821 tattactttt atggcagttg ggaatttagt ttattggtat atatatggct tagggatata
    14881 tatatggttc atgacaataa ggctttttgc ttttacccat acaaaccgaa acgatattaa
    14941 gctttcattg cctcaatact acaagtcatt ttttatggca ttaggcctga gcggcatttg
    15001 tttgtatgtc attcatttat tgactgctga ctggtataca ttagtggtgg tcgtctgcat
    15061 agggagccta agttggtgcc tgttttatcg tttcagatag tggttatgta gagttattgt
    15121 tttaaaacga ggagaggggc tcttttatga attcaaatgg tgataaattg tcgttatctg
    15181 ttcagaattt agcgaataca aatgagatca caattgttca agcgataggt gagctaaaga
    15241 aatcgggaaa agatgcaata ccagttttgg ttgaggcctt aaaagaggaa ggctctttgt
    15301 gtaatattgc tgcagctgtt ttaggtgagt ttggggaaga cgcgagtgaa gcagcggagg
    15361 agctatcatg tttattaaaa agtcatgccg aagatacaag aatggcagcg gcgatttcat
    15421 taatgagaat cgggaagccc agtctgccct ttgtcatcaa aatcgctcaa gaaagtgaag
    15481 ggcaatcgtg cttttgggca tcttggtgta ttgcatggat tgatccgtct tgcattgaac
    15541 ctaagatgta taaatgtcta aaatacgagc atgaacatcc ttcaggaata gttgctccgt
    15601 ttgcggctga agaggcgtta ggaaagctga ttgcttttca gctgaaagat aaggaggact
    15661 gaaaggatga aagatgaaca aatgttgact gaatggccaa gtcatttacc atggttgaat
    15721 caatcacaga atgattttac atttccaagt gacacatatc ttcttcttta tttttggtca
    15781 atgagctgtc caaactgtca ccaattaaca gacaaagtcc ttcaagatat aaaggatatg
    15841 aatgtgaaag taatcggagt acatgtcccc tatatagaag aagagaaatc tatggaggtt
    15901 gtcttgacgt atgctcttga taggggacta gctattcaga ttgtattaga ccaaaactat
    15961 gagatcgtca caacttgtca cgtacaaggc atccccagct tttgtctatt aagtcaatac
    16021 ggtcagatca ttactaaaac gatgggagat gttggttggg ataagatgtt aaaaaagatt
    16081 gcaggcttgt gaaattttcc gtcttgtatg tgcgacaaac ggttgaatat tatgatgaaa
    16141 cggtccttcc tataagcagg aaggtttttt aatgaaatat ttttttatta gtaggtaaat
    16201 tcatcaaatg ttctgctatg ctccaaatgt acacctttcc gtaagggcaa agttaaatgt
    16261 gaaaataaaa ctgttccaaa gttaatcaga aatttatttt catattgtat cctttcagta
    16321 tcacgtgaaa ggagcatcat atgaaaacat tatggaaagt cctaaaaatt gtttttgtca
    16381 gcttggctgc tttggttttg cttgtatccg tctcggtatt tatttatcac catttccagc
    16441 taaataagga ggcggcactg ctgaaaggta aaggcacagt agtcgatgtt gacggtaaaa
    16501 agatgaatgt gtatcaagag ggaagcggga aggatacgtt tgtgtttatg tccggttcgg
    16561 ggattgctgc gcctgcttat gaaatgaagg ggctgtacag caagttttca aaagaaaata
    16621 agattgctgt tgtagatcgg gcaggttatg gatacagtga agtgtctcac gatgacagag
    16681 atattgatac ggtattggaa cagacgagga aagcgcttat gaaaagcgga aataagcctc
    16741 cttatatttt aatgcctcat tcgatatccg ggattgaagc gatgtattgg gcacagaaat
    16801 atcctaagga aatcaaggcc attattgcga tggatattgg attgccccag cagtacgtca
    16861 cgtataaatt gagcggagtt gacagattga aagtgagagg gttccacctg ttaacctcga
    16921 ttggttttca tcggtttatg ccttccgctg tatataatcc tgaggtgatt cggcagtcgt
    16981 ttttaactga tgaagaaaaa gaaatctata aagccattaa ctttaagcaa ttttttaatg
    17041 cagatatgga gcatgagctt ttacagtctt accaaaacgg cagcaaatct gtgaatctgc
    17101 cggcaccaaa ggaaactccc gtcttgattt tagatgcggt ctctgaccaa aatagacatt
    17161 caaagtatgc tatacaaaac cgaaaagact atgaagcgtt tgcggctcaa ttcaatactg
    17221 ccgatataaa ggaactgagg ggaacacaca gtatttattt atatcagcct gatcaaatat
    17281 ataaactgtc catggagttt atgagaaagg ttcgctagga tgaagggata tcatatttta
    17341 atcgttgagg acgatgtgat gattggtgat ttgctgcaaa agattttgca gcgtgaggga
    17401 tatcgtgtga tatggaaaac agatggagcg gatgtgcttt cggtgattca gaaggtggat
    17461 ttggtcatta tggatgtgat gctgccgggt gaagacgggt atcaaatgtc tgcaaaaatc
    17521 aaaaagctgg ggctgggcat tccggttatt tttctctcag cccgcaatga catggacagc
    17581 aagcttcaag gtttgcagat cggcgaggat tatatggtaa agccctttga tccgagagag
    17641 ctgctattaa gaatgcggaa tatgcttgag catcattatg ggacctttac gcaaatcaaa
    17701 catttgtata ttgatgcggt aacgaaaaaa gtgttcaatg aaagcctgca tgatgaggta
    17761 ttatttactg cgattgagcg gaaaattttc ttttatttat atgaaaatag agacagtatc
    17821 ctgacaaagg aacatttctt tgaatatcta tggcaactcg aagatagaaa cccgaatatt
    17881 gtcaatgtgc atattaaaaa aattagagct aaaatcaatg atcaagcggg tgagatgatt
    17941 gaaaatatat atggagaagg gtatcggctg aataccgttg tgaagaaatg aagcttaaga
    18001 caaaatatca gttgttattg tttacggccg tcattagtgt tccaatgcta ttgctggcgg
    18061 taagtgtttt gatgtcggtg atttatgaca gcatgtttaa accgatgaat catggtatgc
    18121 cctttcacag gtcgtttgcg tacccggcaa tgatcgttgt atttttgata tcactcttat
    18181 tgttagcttt tttattttca aagtcgattc attctctgtt gcataaaatc aatctattaa
    18241 atcaaaccat tcggcatttg gcgagtgatc aaagggtgcc cgataaaatt gaagtgaagc
    18301 gtgctgatga aatcggggaa ctgatcaagt cggtcaattt gttaattgaa cggacgacat
    18361 atcgtgaact ggagctgaga cagcaagagg aaatcaaaaa ggagcttttg caaaaactgc
    18421 ggcatgacat taatacacct ttaacggctc tcaggctgca gttattttat ttggaagacc
    18481 aatgtcatgg tcaggctgta ttcgaatcat tgtatcagca aatcgaatat atctcggaat
    18541 taaccaatga attcaatcta tattccgctg agacgctgga aagctcttat attgtaaatg
    18601 aagaagtgcg tctaaacgag ctattagaaa cagcggtgaa aaagtgggat tatttataca
    18661 gtatgagtgg gattgagctg cactataagg cggcagatca agatgtgata tggatgagca
    18721 acgcgttatg gatgcaaagg ctgtttgata atatttttca aaatacgtta aagcattcaa
    18781 aagctgaaaa gatggaagtc acgattgaac atgacaatgt ttttattcgt gatgacggta
    18841 ttggatttga tcggaatgag agcagtgagg gacttgggtt aaagattatt gaggatacat
    18901 gcaggctgct tgcgattact tatgagctgc atacaaatga tagcggaacg gggttcttgt
    18961 tttcaaaaga gtgaccccgc tgatgttttt ctttctccta taaaatttat ataataggga
    19021 gaaagaaatg gggtgaacag catatgttta aaaaaatcat caaaacgatt aagtacctct
    19081 caagcagttc tagtgaccga tatcgcagac accggcatta cagcagcagc cggcgcagac
    19141 attatcgcag ctacagcagc tcgggcaaaa gaagacacta cgaccgttat ggcggcagtc
    19201 atcgttacaa acgccggagc tacagcagca gttaatccaa aaaagttctt gttccgcttt
    19261 tgggacaagg gtttttttat gtgaccgatt gaatggcccg gtttagatcc tcgcgaatgg
    19321 aagcggtgtg ctgatactct tcctcaatgc ccaataatct tttcagcagc aaggttactt
    19381 cctttgtcag tgttaattcc tccagccaag tgccgttttt cttctttttt cctttatatt
    19441 gagagtacag caggaataac agcgtttctc cgagatcgaa gaagtcatcc tgttttcgta
    19501 cctttatttc ctccatttct tcaggagtca attgtttggc aaggccgaaa tcgatgaggc
    19561 agagcctgcc gtcattgatg atgatattag gcgttctgat gtcgctgtgg aagataaggc
    19621 gatcatgcag gtattctata atctcaagca gctgcgaaat cagttgtaat gccataagct
    19681 ctgtgaacgg ctgttttcga aaaaataata attcttctat attctctccc tcaatgaact
    19741 gcatgacata ataagcctgt ccgtctatga tgaactcatc tatgaagccc ggaatttgcg
    19801 ggtggtgaat gctattgagc agttttattt cctgttggaa tcggactttc tctttttcct
    19861 ttttcgcttt tgtcggccga agctgtttta agacataagg tgtttgagtt aggatatcgg
    19921 tgcacaaata aaccaaaccg tagcctccca taccgaggca ctcttcgatt ttgtattgat
    19981 gatttaagat aacgccgttc tttagagggc ggtcaaatag cagttttttt agaagtttta
    20041 atgccatgtc tgcacttccc ttggttgtac tgactatagt ttaccttcta gacagagaat
    20101 aaaaaagagc cggatcaccg gctcggtata agttaaaact gctttgtcac gtcgtattca
    20161 taatctattt ttgcttttac gttgctcatc gtcgatctgg ctgtcgctaa tgtattatat
    20221 ttaaaactcc atacctttgc cacactgagt tgatctgaca aagagatatc ataagaccct
    20281 gaagtcgagc tgtttacaag agcacggcgc cattcgttgt tttcgctcgt catgatcagg
    20341 tggcgtgtat ttccctggct tggtgtttga gtggcggttg tctgaactct ggttacaatg
    20401 gcatcacgcg gtatcccgga ttggtttgtt aaatcaacct tgatcacgct ggaatcagaa
    20461 cctgaggggc taaggcttgt atttccttta ttttcagcaa cgccgctgaa ttggaatgtt
    20521 ccgctgcctg atttgattcg gtcttcaatt gaaagtgtaa aatacatgtt tccggtatag
    20581 gtgcctcgtg acactttcac ataaaaggta tccgtcgtgt tttgggcgtc tgcatttgca
    20641 taaataaaag aagaaaacgt attagggtta atgacttctg tcccttgaga aacaggtatt
    20701 ctattcttat cataaatttc aattttcatc cctgtatacg cgctctggta tgtactcctc
    20761 acgtatactt tttctccctt attagccgta aaagtgaaat aggcttcatc ttgaccagct
    20821 tccagtattg ttgtatcgat atttttatat ttccaataac cgatcggcat tgcggtatca
    20881 aatgaattgt ttcctgtgat agcagtgact ccggcagctg atgccgaata cgtaaaggtg
    20941 aataagacag acagcataac agcgaatgga ataagccatt ttttcaccat gcaaacaacc
    21001 tccttttatt tccatcatac ataataacga tttaggtgta aataaatgtt ttttgaggtt
    21061 aatatataca ttatctttgc cgataaaaaa gaataagaga gaatactcgg gagggaattc
    21121 aatgcgtctg aatcggcaat ttatccgcac tcagctgatg gcacagaaca tattgagcaa
    21181 gaatgcgcct gccaaacggg agaatgcgac tgaaaatcca gcggcagttc tggaaaaggc
    21241 atacagcagg cttaagtcac aatcttcaac tgggggaatc aatcagttca attattctaa
    21301 aaccagcgtg tcgggaaaca gcggggcgtt cagcaaagtg tatcaatcag cgaatgatcg
    21361 aacagtgaca gacacagggg aagaaacagt gattcaatcc caaaacccct atgaatctga
    21421 gagtgatatc agaatcaaaa tactagatga aaaatacagc aggatgaatg cgattaataa
    21481 aacaaagtct gatccattag gctatattaa ggataagtac caaaattcaa agtctcctta
    21541 tttcagaagt gatctgtcag ctgcagaaag acaggccgct tacgataatg aaacagaatg
    21601 gttattcaaa gggaaggcgc aaaactataa ccttcaggat gctgtgtttc ggaatgtcac
    21661 atttcatggg gaagtggaag ctgagaatga aaaggtgtat cagcggggac aggttaacca
    21721 gcagctgcaa gtactgttga atcgaaacca tattcatatt ccagagggga cagagctgac
    21781 gtttacaatc acaccgattg actatcaggt gcgggtaagc gggtcagacg atcaggatct
    21841 gatcaagcaa attgagcaag tgctgcaatc tggagacaac agcaaagaac tatttttgca
    21901 catcatgaaa agccaaagca gtgattcagc acaattttcc gaagaggcct atcaaaagta
    21961 tcaggctgct cgtgagatgt atgaagttac aggctaccat ttgaaggatt tagaagtgat
    22021 tgatgggcgg tacgtcacgc ctgagggacg tgacttaatg gatgtatata aggaagagct
    22081 tgaaaaagat ccagtgcaga aacaaacggc ttcttatgct atatcttact atcgttcaga
    22141 gctcagtaaa atcgcggaag ccgggtataa tgccattccg gatttcatcc tttcaattga
    22201 ttacagcaat ggatctctga gagatgtggg acaaagcaag agctatggga ccggagatac
    22261 cgggtggctt gaagcattaa agcgtcaaac gggtgtgaat tattaggtaa gctgttcatg
    22321 taggacagct tattttttat gagaatctaa ggggtgaatt aatcccaata ttcaaataat
    22381 tttattattt ttatataaaa gattttaaaa gaagtgaacg attcaaaact ctgaacaaag
    22441 gtgtttgcct gaaaaaaaca attgtatttt ccagagaaat ttattatgat gaaataagta
    22501 atttaggaga ttatataaca attttaagtt tgaattttct gattgttatc actgattcat
    22561 gtgaaggcaa gcaggtctgc tgttttctca tttatgagta ttttgttagg aggaggaaga
    22621 ggagtggcaa ataaagaatt aaagaggggc ctgggcgcgc gccatattca gatgatcgcc
    22681 ttgggcggta caatcggtgt tggcttgttt atgggttctg ccagcacgat ttcatggact
    22741 ggcccatctg tccttctggc ttatgcaata tgcggaattt ttatcttttt tattatgcgt
    22801 gcgatgggtg aaatgctgta tgtcgagccg agcacaggtt cttttgcgac gttcggccat
    22861 caatatattc atccgatggc aggttatata acagcatgga gcaactggtt ccagtggatt
    22921 atcgtcggca tgtcagaaat tatcgctgtc ggtt
//
