LOCUS       gnlProkkaNOEMIMDN_46   10228 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NOEMIMDN_46.
ACCESSION   gnlProkkaNOEMIMDN_46
VERSION     gnlProkkaNOEMIMDN_46
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 00:23:48
            Original ID  :: gnl|Prokka|NOEMIMDN_46
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10228
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10228
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[4618:8892]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4619..8892
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10228
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10228
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..1370
                     /locus_tag="ctg38_1"
                     /transl_table=11
                     /translation="MLFGKFGIGHLLSRLSLEKQDGVSASELLLSLCLFRIVGESIHSI
                     CKHKIYELSNHGKNCFYRMMIRPQMDWRRLMNHFALRYMCLLRKYGEVPQSDTTTCFII
                     DDTVLEKSGVRMEGISRVFDHMKGRCVLGYKLLLCAFFDGKTTIPFDFSLHQEKGKQGN
                     YGLTRQQLKKAYHTKRNTGNPDYKRFQECKMSKLEVAMDMLRRGWKMGLHAKYVITDSW
                     FTCEQLMTCVRSIGKGAMHFVGLAKMGKTKYTISGKKKNAAELIATYERERGKNCRKYK
                     CRYIQLNGNLGDIPIRIFLIKYGRNSAWNVLLTTDTTMSFVKAFEVYQIRWNIEVMNKE
                     TKQYLGLGGYQGCDFNGQIADATLCYLTYTVMALEKRFTEYQTMGELFSDMEGDLMALT
                     LWKRVLTCIERILRILGEILGMTPQYLMATISGNDKEMSKILVMAEALEKWDEVCG"
     CDS             1361..1651
                     /locus_tag="ctg38_2"
                     /transl_table=11
                     /translation="MWIVCITSVRHVLTVNGYGGRQTKENEKSWCFKGWETLVHNFTEK
                     YVSKIYKSGQPHQNVNNLIINTCRFCINRDKWGGYKDEKFQQFTISPLKNA"
     CDS             complement(2618..2806)
                     /locus_tag="ctg38_3"
                     /transl_table=11
                     /translation="MLKVTDECTACGACLSICPKSCISFKSNEEGFLYPHIDIEKCVDC
                     DLCSKFRIYNRLLLNIL"
     CDS             complement(2790..3785)
                     /locus_tag="ctg38_4"
                     /transl_table=11
                     /translation="MCSKDNFLQEVRALCIFTVILLHVPFQGHDNISFNTWLMSKQLIT
                     FPVAVFFFLSGYFYSFRNYKSRIVKLLCPFLFWNMSVHLIKFIRGESGFNIENFLLGNG
                     LPYYYLAVLLQIVLFHYIIFKYWSEMVYRVLSISISIISLMAYYYFSISYSIHFNCYLY
                     FPFWILFYTLGTFGKKYWRNLISKIPFCVILLFILISVFLMFFEANLMYYILFQEGIAG
                     SQVKFSSWVYSILIVLLLLKIDYSIDENVTRNFGTLIGDYSYGVYLIHIFILSLIYKLC
                     IVVFNDNYNVLLPFIAASITLVISVFMIYILNKCLPPFILKFLGLYVKSN"
     CDS             complement(3788..4606)
                     /locus_tag="ctg38_5"
                     /transl_table=11
                     /translation="MLKKRLDYSQLKVIQLNILKDVDAFCRENNITYYLTYGTLLGAVR
                     HQGYIPWDDDIDIAMPRKDYEKFLSNYNLNGSKKNVYQVVAIELNNAYPYPFGKVQDLS
                     TVLLEYSDINYPLGINIDIFPIDGLPVDLKKSDKHFLKIKWLMMIMNLKKVKITIKRSF
                     LKNLILLIGKILTLLIPYRFIVRKMSYIAQRYDYEKSDYVSNLSCPDGKHERTSKRVFE
                     NSIEILFEGNNFYAPIGYHEWLHNIYGDYMKMPPVPERVSHHKFEIYKIL"
     CDS             complement(4619..5728)
                     /NRPS_PKS="Domain: Aminotran_5 (30-293). E-value: 6.4e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg38_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.5; E-value:
                     1.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_6"
                     /sec_met_domain="Aminotran_5 (E-value: 7.9e-32, bitscore:
                     99.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMKSVNTVLVNK"
     aSDomain        complement(4850..5638)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_6_Aminotran_5.1"
                     /evalue="6.40E-34"
                     /label="ctg38_6_Aminotran_5.1"
                     /locus_tag="ctg38_6"
                     /protein_end="293"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIK"
     CDS             complement(5725..6861)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 71.8;
                     E-value: 7.9e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_7"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.5e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4e-21, bitscore:
                     64.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGVALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             complement(6873..8174)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_8"
                     /sec_met_domain="CTP_transf_like (E-value: 1.3e-12,
                     bitscore: 37.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 9.2e-123, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 4.6e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             complement(8194..8892)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_9"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.2e-14, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             complement(8906..10189)
                     /locus_tag="ctg38_10"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SVLSIFAIYCYFKQQLNSLILIPSEIHD"
ORIGIN
        1 ttcatctttt tggcaagttt ggcatcggtc acctattatc tcgcctttca ttggagaaac
       61 aggacggagt ttcggcttcg gagttgctcc tctctctttg cctcttccgc attgtgggcg
      121 agagcatcca tagtatatgc aaacataaga tatatgagct ttcaaatcat ggtaagaact
      181 gtttctatcg catgatgatt cgcccacaga tggattggag acgattgatg aaccactttg
      241 cactgcgtta tatgtgccta ttgcgtaagt atggcgaagt tcctcaatca gataccacta
      301 catgtttcat tatagatgac accgtacttg agaagagtgg tgtgaggatg gagggtatca
      361 gtcgtgtttt cgaccatatg aaaggcagat gcgtattggg ctacaagctg ttactttgtg
      421 ccttctttga cggcaagaca actataccct ttgatttttc actacatcaa gaaaagggga
      481 agcaaggcaa ctacgggctg acaagacagc aactcaaaaa ggcatatcac accaagagga
      541 acaccggcaa tcctgattat aagcgctttc aagagtgtaa gatgtctaag ctggaagttg
      601 ccatggatat gcttcgccgt ggatggaaga tggggttaca tgcgaagtat gtgattaccg
      661 atagttggtt cacctgcgag caacttatga catgtgttag aagcataggt aaaggggcaa
      721 tgcactttgt tggacttgca aaaatgggaa agacaaaata cactatatcg ggcaaaaaga
      781 aaaatgctgc agaactcatt gccacctatg aacgtgaacg aggaaagaac tgtcgtaaat
      841 acaaatgtcg atatattcag ctcaacggca acttaggaga tatacctatc agaatcttcc
      901 tcatcaagta tggtagaaac tccgcatgga acgttctgct caccacggat acaacgatgt
      961 ctttcgtaaa agcctttgaa gtgtatcaga ttagatggaa catagaggtg atgaacaagg
     1021 agactaagca atatctcgga ttaggaggtt atcaaggttg tgactttaat ggtcagatag
     1081 ccgacgcaac gctgtgttac cttacatata ccgtcatggc tttggaaaag agattcacag
     1141 aatatcaaac catgggcgaa ctcttttcgg atatggaggg tgatctcatg gcactcacgt
     1201 tatggaagcg agttcttacc tgcatcgaac gcattcttcg cattttagga gaaatacttg
     1261 gaatgacgcc ccaatacctt atggctacaa tcagcggaaa cgacaaagag atgagcaaaa
     1321 tccttgtaat ggctgaagcg ttggaaaaat gggacgaagt atgtggatag tctgcataac
     1381 ttctgttagg catgtgttaa cagtcaatgg atatggggga agacagacaa aggaaaatga
     1441 gaaaagttgg tgttttaagg ggtgggaaac tttagtacat aactttacgg aaaaatatgt
     1501 ttctaaaata tataaatcag ggcaaccgca tcaaaatgtc aataacctga taatcaatac
     1561 ttgtcgattt tgtattaata gggataagtg gggtggatac aaggatgaga agtttcaaca
     1621 atttacaata tcccccctta aaaatgcata attttgtatt tgtctgaata atagcctgtt
     1681 gtcaaaaatc atgtttctta aaaaatatta cccgcaaggg aaatttgaat tatatggggc
     1741 aaaaaatcaa tttttatggg gtagtagttt cgatttggac caatggtttt tttaggaaaa
     1801 tggacaataa gggagaggag gaggttgaaa actacgtttg tttcctaagc taacgttatt
     1861 ttgatgcggt tgccctgtat ataaatagac agctgtgggg aaaatgtggg gaaaaattag
     1921 ataattaaaa aggctaaatg actgaaaata atcacttagc cttttaatcc gtacccagac
     1981 ccgtacttcg taattgctgc gcccatcatt caagactgtc aaatcgggtc tttcctgtca
     2041 agccaatgat gcctatgcgt atgccaaaca catggattac ggatttctcg ttccgtgaac
     2101 aaacacttta tccgcaactc tgctatgtgg tgtattggct taactccatt tctatgggca
     2161 acacttttgt tgcagatttc aagcagcttt tatcgaaata cccatcagta agaactcgtt
     2221 tattaggctt tcctcataat tgggaacaag agcctttgtg gagataaaat aattgccctg
     2281 tttcttaaaa agcactgggg caaaccagct ccgtctttaa ttgtttccaa taaatggatt
     2341 gtttcaagcc cctatagaaa gagaacaaaa attcctgtgt gaaaattaat ctacgacaag
     2401 gagcaagcaa ggagcaatat caaacaaaaa tcaatacctt tgcagtacat atgagataga
     2461 ccaaaacaaa agtggaatat cggaaacgaa tagcaaggaa aagagaagaa acgacccaag
     2521 ttgatgtcct ttttgagtta ataatcaata aaagcgttaa atcttcacct tttagaatgt
     2581 gcaattaaaa ataacaacca tatttctgac ttattatcta taaaatattg agtaataatc
     2641 ggttgtaaat acggaattta gaacacaaat cgcaatctac acatttttct atatcaatat
     2701 gtggatataa aaaaccttct tcattacttt taaaagaaat acagctcttt ggacatatag
     2761 acaagcaagc tccacaagcc gtacattcat cagttacttt taacatacaa tcctaaaaat
     2821 ttaagtataa agggaggaag acatttattt aaaatataaa tcataaaaac tgaaataacc
     2881 aatgttatag aagctgcgat aaaaggcaat aatacattat aattatcatt aaaaacgaca
     2941 atacataatt tataaattaa agataatata aatatatgaa ttaaatagac tccatatgaa
     3001 tagtcaccta taagtgtacc aaaatttcga gtaacatttt cgtctattga ataatctatt
     3061 ttaagtaaaa gcaacacaat tagtatagaa tacacccagg aagagaactt aacctgagag
     3121 ccggcaattc cctcttgaaa caaaatataa tacattaaat tagcttcaaa aaacatcaaa
     3181 aagacagata ttaaaataaa caatagaatt acacaaaaag gtattttaga tattaaatta
     3241 cgccaatatt ttttcccaaa tgttcctaaa gtatagaata atatccaaaa gggaaaatag
     3301 agataacaat taaaatggat agaataagaa atggaaaaat aataataggc catcaaactt
     3361 ataatactaa tacttatgga caatactcta tataccattt cgctccaata tttaaagatt
     3421 atgtaatgaa ataacacaat ctgaagaagt actgctaaat aataataagg taatccatta
     3481 cctaataaaa aattttcaat attaaatccg ctttcccctc taataaactt aattagatgt
     3541 acactcatat tccaaaataa aaaaggacaa agcaatttaa caattctact cttataattt
     3601 ctaaaagaat aaaaatatcc agataaaaag aagaacacag caacagggaa agtaatcaac
     3661 tgctttgaca ttagccaagt attaaaactt atattatcat gtccctgaaa tggtacatgt
     3721 aacaatatta cagtaaatat acataatgca cgaacttctt gaagaaaatt atccttagaa
     3781 cacatgatta cagtatctta taaatttcaa atttatgatg agatactctt tccggaactg
     3841 gaggcatttt catataatct ccataaatat tatgaagcca ttcatgatat cctataggag
     3901 catagaaatt attaccttca aataaaatct ctatactatt ttcaaaaact cttttagacg
     3961 tccgttcatg tttcccatct ggacaagaca agttagaaac ataatcagat ttctcataat
     4021 catacctctg tgcaatataa gacattttgc gcactataaa tcgatatgga atcaaaagtg
     4081 tcaaaatctt ccctattaat aatattaagt tcttcaaaaa agaacgtttt attgtgattt
     4141 ttactttttt aagattcatt atcatcatta accactttat cttcaaaaaa tgtttgtctg
     4201 attttttaag gtctacaggt aatccatcaa tagggaaaat atcaatattt atccccaacg
     4261 gataattaat atctgaatat tctaataaaa cagttgataa atcttgaacc tttccaaaag
     4321 gataaggata agcattattt aactctatag caacaacttg atacacattt tttttacttc
     4381 catttagatt ataatttgat aaaaactttt cataatcttt cctcggcata gcaatatcaa
     4441 tatcgtcatc ccaaggaata tatccttgat gtcttacagc ccccaacaaa gtcccataag
     4501 ttaaataata agttatatta ttttcacgac aaaaagcatc tacatctttt aatatattca
     4561 actgtataac ctttaattgg gaatagtcca accttttttt caacatgaat gagctaaatt
     4621 atttattaac taataccgta tttacgcttt tcatcacctc aaagaacctc tcaatatcct
     4681 ccacatcaat ctctcccaac gcacaaagcc ggaatgtatt cgttgtggaa atcttacccg
     4741 ggtagatcgt aaagccacgt tcatagcagt aatcatgaac cttatcaaaa tcccagaggg
     4801 gatcatcagg atacaataca gaaacaacaa gacccgactg ccattcacgt ttgatcgcat
     4861 actgaagacc aagctcttgc aaacctttat ggatggcttc aaagaccctc ttgtgacggg
     4921 cgaatttagc ctcttcacct actgcaaaat attcatcaag agcctgacgg gcagcgtaaa
     4981 cggtttgaac aggaggagta aaatgcatct cacccgtctt ctcaaagtaa tcgtattgta
     5041 aatagaggtt acaatagtag gagcgtttcg gataatccct tgaagcacgt atcagggatt
     5101 catcacctat gataaaggaa agccccgtca tggcctgaag gcctttctga gccgaagcca
     5161 tacaaaagtc aacattatcc tttccgatat caaaaggaat catacccagg gaggaagtgg
     5221 tgtcgacaac aaaaacggca ccgtgcgaat gggctatttt tccgatctca cggatggggt
     5281 tcaagatacc cgtacccgtt tcatggtgcg tggtatagac caaagcgatg tccggattgt
     5341 cggaaagcgt cttttcgatt accgacaggt cgggaagttc gtaaacggaa aacttcaaat
     5401 cgatatgggg aagaccgtaa tattcgcaga cttccaccgc acgggtgctg taggcaccgt
     5461 tattgacaac cagaactttc ttatccgcag gaagaagaga gttcaggcag atatcgatat
     5521 tgatcgtacc cgagccgcaa aacaggacgg ccgtatgttt ggagaggtct ccatgcgcaa
     5581 cgcggaccag gtcgtcacgt aactgtttca tcatacccgc aaactctttc tcacgcggac
     5641 agatatcggg aacaacctgc gccagcttca ccgtatccgt cgtggtggcg ggacccggat
     5701 tcaaaaggat ctttctttcg atattcatga atgcgtatct tttaaaaatg ccataaaatg
     5761 ctctttattc tctaccggag tagtcgtagg gcgacccaga tcatcacgtg aatcgatccg
     5821 gaccttaatt tcaagaagaa ccggaccgga caggccggac agcttctcaa gcgcacacga
     5881 aagcccttcc ttgtcggagg cagtcagtac atgcgcataa ccgcaacctt tcgctatcga
     5941 ggcgatatcc agacggaaac cgagcgtggg ttgaccgccg acagattcat gggcaccgtt
     6001 gttgaaaagg acgtgcctgt aattcttggg agaaagatcg ccgatattgc tgacagcacc
     6061 catgtgcatg ataaaggcac cgtcaccgtc aagacagtag acacggcggt caggcttctc
     6121 aagggcaacc cccagggcaa tggaagaact gtgccccatg gaacccacag ttaggaaatc
     6181 ccttgcgtgc ccctgccctt tcgattcacg gtactcgaaa agctcacggg agagcttgcc
     6241 cgtggtggaa accacaatgt cattgtcccc gaggtggtcg acaacctgca ttagcgcctc
     6301 ctcgcgggac agaggatagt cattcaaggc ttcctgacgc aatttatatt ttccaaacgt
     6361 atctttacgg atgacaatcg catggggaat cgaccggctc ttcgccgaga caaccgcgtc
     6421 atggatctgc gccagggcct cgtcttcatc cgtatccaga attataaaag gaattttcat
     6481 ggctttcaga agatcaaggg taacctcgcc ctgcttctta tgctggggtt cgtcttttgt
     6541 gccgggctca ccgcgccagc cgaccagcaa aagaagagga aggctgtaca ctttctcgtc
     6601 cgcaagggac aagaggggat tcaccgtatt tcccagaccg gagttctgca tataaaccaa
     6661 aggaacgttg ccagaagcca tataataacc gcaggcaatg cccaccgcgg aaccttcatt
     6721 ggcggcgatg atatgcttac cacgcggagc atgatccgtg atataggcgc aaatattctt
     6781 caaaagggaa tcgggaacac ccgtaaagaa gtcaacaccg tgatgaagga acgtatcgta
     6841 tatcttttct acacttacca taaccgtctg atttatttag tgcccggaat caattccaga
     6901 atttccttga taggcataca aagcggacgg acctcctcgg cgcgctcgtt ttcaaggatg
     6961 gtcctggcca cgttcatcat ggccgggtaa gcggcacgga gaaggtggtt ggcgtaaatg
     7021 actacgttgg caccccattc gtgaagttcg gattcgtgca catggtcata agtcgtcgga
     7081 acaacgacaa tgggaacatg ggcgtattct ttgcggaaag tccggcagaa ctcacggata
     7141 tcctcacccg acttatcctt gctgtggatc atgatgccgt ccgcacccgc ctgtacatag
     7201 gcataagcac gttcgagggc gtcactcatg ggtttgccgg caataaggct ttcgatacgc
     7261 gcaatgatca taaagtcacc ggtgacctgg gcattcttcc ctgctctgat cttatcgcag
     7321 aaaccctcga tactatcctg agtctggata gcgtcagtac caaaaaggga attcttcttc
     7381 agaccgactt tatcttcaat gattaccgca gaaatgccgt gacgttccag agtgcgcaca
     7441 gtaaagacaa agtgttcgat cttgccaccc gtgtctccat caaaaataat aggcttggtg
     7501 gtacattcaa ggatattgtt caggtcctgt aaacgggtgg taaggtcgac cgcttcaata
     7561 tccggtttac ccttactcgt ggagtcggtc aggctgctgg accacatgcc gtcaaagacc
     7621 tcgcgcttat cacccttctg gacttcaaga ttctcaataa tcagaccgca aagaccgtcg
     7681 tgagcctcca ggatacggac cacaggcttg gcctggatca ggcggcggag ggacttaaga
     7741 cgtacgtcag gggtagtccc gatcgccttg atatccttgt cgagcgagga ggagttgatg
     7801 ccccgggtat aagggatctc gattaccttg cccccctggg cgttcatcac ctcaaaaacc
     7861 tgttcgcgca cctcgcgcaa cgggcccgtt ttccagtcgt cgccgtggat gatatagtca
     7921 ggcttgagtt tttccagatt cggaacatag ctccagtcct cctggggaac aacctcaaaa
     7981 acccccttga tattctcaac aacctcctta cgctgatcat aggtaaggta agggaggcgt
     8041 ttgtgttcgg cgatggcctt gtccgtcagc agaccgacga tgacatcacc gtatttagta
     8101 gcttcatgaa taatatggat cagccccgga tgcatgatat ccgcggtcat accgacatag
     8161 attttcttgt tcatatatgg aaaagatttg tttttaacaa tagcggatga tgtgctcctc
     8221 ggcatacgaa aggtcggctt catcatcgat ttcataccat ttaagaccct ccaccctgag
     8281 cacacggaca ggggaaacgg aacgggacat gcggagcagt tcgtactcgt aacccagttt
     8341 aggctgggac tccaggatgg tcgcataatc ggcgcacatc cggcggtaga aagtattgga
     8401 aagtttatgg ataccgacca gctcgccttt tgcctcaagg gcgttcttgt ctaccgaaca
     8461 ggaagtaagg atgtgattgc ggtcatattc cacataatac tgatcctgga acttggtcag
     8521 agaagagaca agcatcacat ccgggaattc gtcatccagt agcgagagga tggccttgcg
     8581 ttcaaaaaca aggtccgatt caagcagcag gaaactgtca tcgcctatca cgtcacgcgt
     8641 attgtacaga gtgtacatac tgttagtatc ggcataacgg ggactgaaac aggtctctat
     8701 ctgggggaaa tccgcctgaa gggcttcata agcctctttt ttataacccg taccgaggat
     8761 gatacgttcg ataccgcagg aaagaagggt ttcgatagag cggataatca taggttttcc
     8821 accaacctcc acaaaacctt tgggcacaag ctcggtataa tgcccgaagc gggtaccaag
     8881 accggcagcc atgatcattg ctgttttaat catgaatttc agagggaatt aatataagtg
     8941 aattcaattg ttgcttgaaa taacagtaaa tcgcaaaaat cgacaggaca gaaacaaatc
     9001 ctgaaaaaag ggcagtacgc attagcatga cagtccaaga aatgtcagca gaaacgaagt
     9061 tcttgaccat aaacacaccc gtagtgccca gatagccgaa agaatcggcc aaataaataa
     9121 taaaaacagc cgtactaacc accctaaggg aagcaatcag gcgttctatc aggtaagtga
     9181 aaggaatata ccccatatac agaccaagac cggaaagaat catccaccaa ataggagaaa
     9241 gaaaaccgta cacataaagc aatgtggaaa aaaccattaa ggaaccgcct gtaacggcaa
     9301 tgcaataaat gatattaaga gccaaacggt tattacggac aaacacaatc aggaacatca
     9361 gtacaaggac aaaaacggca atgggaacct ctgtctgagt aaagatcatt gcaccttcaa
     9421 tatggagctc cttccaaata tcggcagcga aagagtcacg aagctcacgg aacacggtca
     9481 gggcaccgta aaaaacaacc agcatgcaga ttccccagaa gaattgcctc aaaaatttac
     9541 gcctgtcttt accatccatc ggagcacgtt tggtacgctg tatgatatct tgctcattgg
     9601 gagccggaat ctgattgaga agccagctgc aaagcaacat aacagggtat accaacaaac
     9661 cggtggtaaa aggcatccaa tattccgaca catgcaaatt atccatcacg aattgtccca
     9721 aggttttcac caaaccggaa gagactatca aagcaacgct cagcccgaca ttcaatattt
     9781 cactgatacg acgtccttcg atatagctaa aaatgacacc ccagatcata cccaggggaa
     9841 gaccgctcag aaaaatagaa cacaccttca aaggaaccgg aagaagtgca aaacccaaca
     9901 aagcaacttc ggaaaaagta agcagcccta ttatataata gatgcggtga cccgctttca
     9961 tcgaaggcag aatacgaaca ccgatgaact tggaaagggc gtagccgata atctcagaaa
    10021 ggacatacag gattttgaca tcgaatcccc aaagaatctc accttcataa atggctgcgg
    10081 taaatggctt acggtaggca taggcacaag tataaaccag aaaaatcaaa acgctggcat
    10141 agagagccaa aacgtaaagg ggagaacggg aaagaaagga acgaatcatt cgtgtagttc
    10201 gctgtacgga tatggattag cttccaaa
//
