LOCUS       c00099_gnlPro..        13256 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|COEODNAD_151.
ACCESSION   c00099_gnlPro..
VERSION     c00099_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 21:50:49
            Original ID  :: gnl|Prokka|COEODNAD_151
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13256
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13256
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[297:3256]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      298..3256
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13256
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13256
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(2..85)
                     /locus_tag="ctg99_1"
                     /transl_table=11
                     /translation="LQRFKRKALLNRSSGEVAEWSIAAVLKT"
     CDS             298..2526
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_2"
                     /sec_met_domain="Gly_radical (E-value: 1.5e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1166.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYKGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2531..3256
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_3"
                     /sec_met_domain="Radical_SAM (E-value: 2e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(3489..4751)
                     /locus_tag="ctg99_4"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVLTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRSEPQQEAIAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(4803..5351)
                     /locus_tag="ctg99_5"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5539..6291
                     /locus_tag="ctg99_6"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6396..7394)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg99_7"
                     /sec_met_domain="LysR_substrate (E-value: 7.5e-47,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 3.1e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7464..7937
                     /locus_tag="ctg99_8"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(8041..9039)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg99_9"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 9.4e-70,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9094..10362)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg99_10"
                     /sec_met_domain="MFS_1 (E-value: 2.6e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(10612..11625)
                     /locus_tag="ctg99_11"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVALKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11648..12784)
                     /locus_tag="ctg99_12"
                     /transl_table=11
                     /translation="MKRITIKQYLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGFSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFVDCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 cggttttcaa gaccgccgca atcgaccact ctgccacctc tccagaacta cggttaagta
       61 gtgcttttct cttaaagcgc tgcaaaggta cgaatcattt tttaacttgc aaattattcc
      121 gcaaaaaaat attagaaaag tatatttgga agtaataacc gccctctggc ttctccccat
      181 aaataggtat ttttatgcta ttcaacataa aataggaccc ttttatatac ctaaaccgaa
      241 aaaaggttgt aaatttgcgc gctctaaagg ataactaacc actaactgat taattttatg
      301 gaactgaata agacctttaa agatggactt tggagcaaag aaatcaatgt aagggatttc
      361 gttagtaaca acatcactcc ttataaaggg gatgcttctt tcctgcaagg acctaccgaa
      421 cgcaccaaag ctgtctggaa tcactgtctc aaagctctcg aagaagagag aaacaataat
      481 ggtattcgtg cactcgacta cacaactgta tctactataa cctctcaccc tgccggctac
      541 atcgataaag agaacgaact gatcgtcgga ctacagaccg atcaggtgtt aaaacgtgcc
      601 atcaaaccgt ttggcggaat caatgtggtt atgaaagctt gccgtgaaaa cggagtggaa
      661 gtagatgaca gagtcaagga tatcttcact cactatcgca agactcataa tgatggggta
      721 ttcgatgtgt ataccgaaga aattcgttcg ttccgttcat tgggattcct taccggactt
      781 cccgacaact atgcacgcgg acgtatcatc ggtgattatc gccgcctggc tctctatggt
      841 cttgaccgtc tgatagaagc taaaaaagaa gatctgcata atctgacagg tcctatgact
      901 gaagcccgca ttcgtcttcg cgaagaagta gccgagcaaa tcaaggccct gaaagagatt
      961 aaagtattgg gcgaatatta tggtttggat ctgagccgac cggcatatac cgcacaggaa
     1021 gctgtacaat gggtgtatat ggcttatctg gctgccgtaa aagagcagga tggtgctgcc
     1081 atgtcactgg gtaatgtatc ttcattcctc gacatctatc ttgaatatga attaagccag
     1141 ggtacgataa ccgaaacatt cgctcaggaa ctgatcgacc aattcgttat caaactccgt
     1201 atggtacgcc acttgcgtat gcagtcgtac aacgatattt ttgcgggtga tcccacatgg
     1261 gtgaccgaat ctatcggtgg acgtttcaat gatggacgta ccaaagttac taaaacttct
     1321 ttccgcttct tgcagacact ttataactta ggcccgtcac cggaacctaa catgactgta
     1381 ctatggagcc ctgagttacc cgaaggtttc aaagcattct gtgcacaagt atctatcgac
     1441 acttcttccg tacaatacga aaacgacgac ctaatgcgtg aagtccgtca atcggatgac
     1501 tacggaatcg cttgttgtgt ttcatatcag gaaatcggaa agcagattca gttcttcggc
     1561 gcacgtgcca accttgccaa agccctgcta ctggctatca acggaggacg ttgcgaaaat
     1621 acaggtacag ttatggtaaa agacatccct gtattgaccg gtgaaacact gaagttcgaa
     1681 gaagtaatgg ccaactataa gaaagtattg atacaaattg cacgtgtata caacgaagca
     1741 atgaatatca tacattacat gcacgataag tattactacg aaaaggcgca gatggctttc
     1801 gtggatactg atccccgcat taacctcgct tatggtgtag ccggactttc aatcgccatc
     1861 gattcactgt ccgccatcaa atatgcacat gtgaaagccc gtcgcaacga catcggactg
     1921 acggagggat tcgatatcga aggtgctttc ccttgtttcg gtaatgacga tgaccgtgta
     1981 gaccacctgg gtgtagacct ggtatatttc tttagcgaag aattaaagaa actccccgta
     2041 tataagaatg cccgtcctac cctctcgctg ctgactatca cttcgaacgt aatgtatggc
     2101 aagaagaccg gtgccactcc tgacggacgc gccaaaggca ttgcctttgc tcccggtgcc
     2161 aaccccatgc acggacgtga taaaaatggt gcaatcgcct cactgagttc tgtagccaag
     2221 ttgcgttatc gcgactcaca ggatggtatc agcaatacat tctcgatcgt tcccaaatca
     2281 ttgggagcaa cacaagagga ccgtatcgac aatctggtga ccatgatgga cggatatttt
     2341 acaaaaggcg cacaccacct gaacgtaaac gtgctgaacc gggaaatgtt gcaggatgcg
     2401 atggaacatc ccgaaaagta tccgcaactg actatccgtg tctcaggata tgccgttaat
     2461 ttcgtgaaat tgagccgcga acatcagttg gaagtaatca gccgcagttt ccacgaaaga
     2521 atgtaattga atgataaacg tacactcata cgagtcaatg ggaacattcg acgggccggg
     2581 tctccggctc gtcgttttcc ttcaagggtg taacttccgt tgcctctatt gtgccaatcc
     2641 ggacacaatt gaagccaaag gagggacagc aaccgaccct gaggaaatag ttcgcatggc
     2701 cgtcagtcag aaagctttct tcggtaaaaa gggaggtatc accttttccg gtggagagcc
     2761 tacttttcaa gcaaaatcgc ttatcccact ttttaaaaga ctaaaggaag caggaatcca
     2821 tatttgcctt gataccaatg gcgggctatg gaacaatgat gtagaggaac tattggaatt
     2881 gactgatctg gttttattag atatcaaaga atttaatccg gaacatcatc agtctttaac
     2941 cggaagaagc aacgagcaga ccctgaaaac cgcagcctgg cttgaaacca atcataaacc
     3001 attctggttg cgatacgtat tagtgcccgg ctacagtgac ttcgaagacg atatccggca
     3061 gctgggagag catcttggaa cgtaccagat gattcagcgt gtagaaatat tgccttacca
     3121 caccttgggt gttcacaaat atgaagcaat gaacaaagaa tatatgctga aaggagtgaa
     3181 agagaatact ccggagcaga tagaaaaggc tgaaaaacta ttcaggcaat atttccggac
     3241 cgtacaagtg aattgactta tataagtgtc gaaattcgta ttcgccacag attacacgaa
     3301 tttacacaga taaagattca ttggccatca atagattaag ttcactctgc ggtgaattat
     3361 gacgactgca cttatttata attttgtaag tcacgatata aaagtctccc tgttcttgcc
     3421 ttaattcatt acaatacaag gcaagaacag ggagataatg taaccggcat attttttgcc
     3481 accctacttt aataagtgaa tcgcaatcct gcctgcaagt taaagttaca aggcctttct
     3541 tttcggatgg tttgtacttt ggagccatca tcaaagaaat acgaaactcc cggttccaca
     3601 tataggccga catgatctgt cgcattgaat tgcgctccca cggcaccggc tacagaaaat
     3661 tgcaaaggct tcacattcac cttatcatcc gccaactttc cataaacaca cttttcaacc
     3721 attcctccgg cagatacata gagtgtaaaa tatttctttt ccagaaaatt ccagtttcca
     3781 cgtacaggaa tacctatata atgcaatttc tgactctgca tcttggtatc cccctgccgt
     3841 ttgatgtcag aagacaacaa cgtataagtc aatcccgtct ctacagagaa acctttggga
     3901 agagacttac gtacagacag tccgaagcta accggctgat gatgttcata atccaccacg
     3961 gcagttgtat tggacttcag gtaagggact ccttcttcaa atataacttc ctgatcggca
     4021 ggaatactca cagctccatt catgatcgtc atcaagtcga ccctgttagt catcggacgg
     4081 ggcgcaaaat tttcggaacc atttgtcgga agtccacctc cattaccgat acccactccc
     4141 atcgaccatt taccaccacg tttagcagaa gagtctccga taggcaactg atacttgtct
     4201 ttaccggacg gtcgccgcgc ttctttcctc tttggaggct gcgccgtcgc actttctttt
     4261 ttctcgattg cagcaattgc ttcctgttgc ggctcagatc tcttttcctc cgtcactgcc
     4321 tccggtcgct tctctaccag ggaggatacc tccggaacaa tcaccggatc agtattcttt
     4381 gccaaatagc ccgaaacagg gttaatactc gtcgttccta ccggcttaac tggttcggat
     4441 acagctacct gtacatccgg caaggcaggt tccggcaata catccgggtt gacagccagt
     4501 gaaggagccg ttgcataacg gatttcatca gctaccggac tattcagaaa atacaaactg
     4561 acagcagtcg ttagcaccaa taccacagct gccgcagcaa ccgcccaccg gcgatacgga
     4621 tatattcgtt tttcggttac aggcatcagt tccctttcca gtcgttccca accggaagca
     4681 ggcatcggct ccgaataatc ttcgagctta tccttgaatg ctttaatcca tttttcgtct
     4741 tctttcatca ttctatttca tttttgaaat ccaaggttca cctcagtatc tgtaaataca
     4801 tgtcaaccat tggtcaccaa ccattctttc actttctttg ccaatacact ttttgcgcga
     4861 aaaagctgtg aggcagaaga tttttcatta atccccaaca tctgtgcgat ttccttgtgc
     4921 gacttatctt caaaggtgta taaattgaat acggtacgat atccggcggg gagttcatta
     4981 ataaattgca tcagcacttt ctgtggtatt gcttcaacag ccgaagcatc cggttcttca
     5041 tacgtttcgg gaacttcatc cagtgccgtg gtctggttca tcacgtcgtt ctttcttaag
     5101 aactgtaaag ccgtattcac cattacacgc tccatccatg ctctcagaga gccttcaccc
     5161 cgccaggtaa acttgtcgaa ggagtcgaaa atcttcagga aaccgtcgtg taccaagtct
     5221 tgtgccatgt ccctgtctcc ggcataacga agacagacac caagcatgcg ccctgcgtac
     5281 tgctcataaa gttctttgcg ggcacgatta tctccctgcc tgcaacgttc cgacagctct
     5341 aattcattca ttctcctaaa cacgtgttta ccttataaat gcagcaaaga tagaaatact
     5401 gcacagagag aacaactctt ttatcacttt tgtttcttta acattttagg atgcaatatt
     5461 tcatcacttc ctgcattttc tcaatacaat aaagaataaa tctcaatgga taaataggat
     5521 aaaaccaaca agaaacttat gaagaaattt aatttaataa cttttgccgt catcctgatg
     5581 ttattgccca ttttacagtc atgtctggac gatgccaaca acgacgagtg ggtcacttgt
     5641 cctccgggtg gaatattggc catcggcaca atgaagattc ccaatgcgga cactccaagg
     5701 gactttttca ttgcattgga caatggagac aatgtacttc cggcagatac ggccgatata
     5761 cgcaacagga aatacactgt tgcagaaggt caaagagtct tcgttggcta tctgcagatg
     5821 ggagaagaga aacccggata tgagaacggt aaaatattca cgatagaaga tatattgacg
     5881 aaagagatca tcccactgac ggaagctaca gcagacagca ttggagacga ccgtatcaac
     5941 gtcacagcgc atgcacttac gaaagattat ctgaccatcg aatatcaata tctgggcagc
     6001 atgaatgaaa ataaaaaaca catgctgaac ttggtacaaa acgaaataac aggtcccata
     6061 aaagatgacg gatatatcta tctggagttc cggcataatg cctttaatga ctcccccaat
     6121 caattgggtt cgagccttgt ttctttcaag ctggatagta tagccgagca attggcgaca
     6181 gccaaaggaa taaaactccg tgtgaacacc atttatgaca atatacagta tgtcacaata
     6241 gatatcaacg aagacaaaaa cttaaaaata aaatcatttc attctcaata aaacaacaag
     6301 aaacacctac acaatcaggc aaaacgagta ataattctga tacataaaag aaataaggcg
     6361 gcgatgtttg tgaaaatatc gccgtcgttt ttatattata ccagacactg aacggcctgc
     6421 agggtaagca tctccttggg aaccgccgcc tgaatctcct ctttcaaaac ctgcagcaga
     6481 ctggtgcgga tgaagtcttt ccgggtcacc aggacaatct gacgggtagg ccgcgggata
     6541 gcaaacggac ggaccagttc tttctgctct tcgctcaatt gcatcactgc cagttcggga
     6601 ataaacgtaa tccccttacc actctccacc atatgcataa aggtttccat actacccagc
     6661 cgatacgcca tttggctgat cttaaccgct tccatctgac aaaaacgaac caactgatcg
     6721 cggaagcaat gcccttcgtc aagaagccaa agccgttccc ctgtcacatc ggacgtacga
     6781 atcacatcgt gcttgaacaa cggttccttc tttgagacat agcccaagaa ttgctcgtag
     6841 aataaggtct cttccgttaa tgcggcatca tccagcatgc tggcaatgat agcagcatcc
     6901 gcttcaccgg tcagcagagc cttgcgaatg tcgggcgtct tcatctccat cacccgtata
     6961 tcaagatccg ggtatttctc catcagttgc ggaaagaaac ggggcagaag ataaggtgca
     7021 atcgtcggta acactgccaa tcggaatgta cccgacaggg agtgctgttc ttcgctgatg
     7081 atctccttga cacagataac ttccgaaaga atcttacggg cctgttccag cactttctta
     7141 ccaatggcag tagggcaaac cggtgtcatg ctacggtcga acagtttcac ccccaattcg
     7201 tcttccagct tttggatcat tgcactcaaa gtaggttgcg tcacccggca atactcggca
     7261 gctttagcaa aatgccggaa ctggtccaca gccagaatat attccaattg ttgtatagtc
     7321 atcgttctct gatttattaa agatatagaa tctatcaatg caaagataga aattttcagt
     7381 ttgacacgaa tcattttgtg ccgtatcttt gttccagata aaaagaagaa atatagtatt
     7441 aactcaaaaa aaacaatatc attatgaaga ctttaaatta tacacatttg gaagaaaaag
     7501 gagctaacac catcgtactg tcattacagc aactgcttgc cgattttcag attcattatg
     7561 caaacctgag aggatttcac tggaacatca aaggacacgg tttcttcgta ctgcacagca
     7621 agtttgaaga tttatataac ggagccgccg aaaaggtgga cgaaatagcc gaacgtatac
     7681 tgatgctggg aggaactccc gccaataaat acagtgacta tctgaagatg gcgcagatca
     7741 aggaagtgga cggagtgaat aaggccgacg acgctctgaa tcatattctc gaaacttacg
     7801 ggcatctgat tgcggaagaa cgtaaaatcc tgtctctcgc ctcttcacac aacgacgaag
     7861 taacagtggc catgatgagc gactacctga aagaacagga aaagatggtt tggatgctga
     7921 ctgcatacaa cggataacag ccgaaagggt gtagccatct gaccgaaaag gtgtagccat
     7981 acaagcaaaa gggtgtagcc atcccggcgg gatagctaca ccctttctgt tttattcgat
     8041 tcagatgata cttgtacgtt tggtaaattc aataatttcc ggaatgtatc cgaatgcgag
     8101 cccggtcact gtatccgcac acccataata gatggcaatc cgtccggtct ccgaatcatg
     8161 aagcgctgcg catgggaaac agacattagg cacatcaccc atacattcgt aatccttctg
     8221 aggtgaaatc agataaggcc ccgaacggaa ttttactttc cagggctgat cgatgtcaag
     8281 cagtgccgaa ccaaaactat acacaaaacc gttgcaggaa gccaatacac catgatagat
     8341 cagtaaccag ccttccgagg tttcaatcgg gataggccct gcaccgatct tggtacactg
     8401 ccaggcactg tcttcgaacg gagccggcga cataacatga cgatgacgtc cccagaactc
     8461 catatcggga gactcgctat agaaaatatc tccaaaagga gtatgcccat tatcactcgg
     8521 gcggctcaac atcgcaaaac gaccgtttat cttacgaggg aacaagactc cattccgatt
     8581 gaaaggaata aaggcattct ccaactggtg aaaagtaaca aaatcatagg tgtaggccac
     8641 accgatagta ggaccatgat agccattaca ccaggtcaca tagtagcggt cttcgataaa
     8701 gcaaacccgt gggtcatatc catagaccca ggttccaacc tcagcgtcat cacattgaaa
     8761 ctttaacggt tcttcgttga tatcccaatg aacagcatcc ttgctgaatc ccacatgcaa
     8821 acgcatgcga cgattagtat catcacaacg gaacacccct gcatagccat ccttaaacgg
     8881 aactacggca ctgttgaata tactgtttga agtagggagc aagtcgcgcg gaataatcgg
     8941 attggccgaa caacgccaca ctacatcttt acatcctgcc ggacgttctt cccaaggcat
     9001 agccggcaaa gcagcacctg caattttaat ttcttccatg attcgattaa attaatatta
     9061 tgtatatatc ttgtttatat tgaaaatctc tttttatttc ttctttccgt ccggatatgt
     9121 gaaaggtacc agccaagtca cgataaaagc cggtatggta gcgataagta cccagataaa
     9181 gaaatcgcga taacccagcc aatcgctcag gtatccgctc atcattccgg gaagcatcac
     9241 ccccagattc ataataccgg tagcaaaagc ataatgtgcc atctgatgtt tgccgggagc
     9301 cacttgctgc atcataaaga gcatcaatcc gacaaaacca aacccgtaac ccaagtattc
     9361 agacacaatg gccataccaa taatccatag atcggaaggc tggtaaaggg ctaacaggaa
     9421 atataccaag aacggaatat taaaagcgca acataaagaa aacaaagtct tccgaagtcc
     9481 gaaagccgaa atgtaataac cggccaaaag cgaaccgaga ataaaagctc ccgctccgaa
     9541 cgtaccatat accagtccga tatcctgagt gctgagtccc aatccaccat ccgcaaccga
     9601 cgctttcagg aacaacggta caatcttgat ggcatatcct tcggcaaacc ggtacaaaat
     9661 gataaagaca atgtagaaag caatatgttt tttttggaaa aaagagcgga tgacttccca
     9721 aagcatattc aatgcgtcac tcatcgtatt cacttcaccg gaagctcctc ctcccgaagg
     9781 caaaatccgg atgtggtaaa gaccgatcag aatcataata cccgcacaca tcaacatgac
     9841 aatcatccag gcatgtacca ctccaaattc atccttcagc atacctgcca gccaaaccaa
     9901 gcctccgttg gcaagtatct tggccagatt ataaaaagct ccctgccaac cgatatactt
     9961 ggcttgctgg gtagcagtca gttcagtcag gtatactccg tcccccgcaa tgtcatgagt
    10021 cgcaccactg agagcaatga tccccatcag agcgatggca taacgaaaaa agtcgggcag
    10081 cggcagcgaa agtgctacca atgcaaatgc cagtccggta ataatttccg tagcgacaac
    10141 aaagtacttt ttcgttttaa acatttccag aaacggactc cataaaggct tcaatgtcca
    10201 gggaagcata atgagagaag tccagaaagc aatctgtgca ttcgacactt ccatatcgga
    10261 aaacataagg acagaaacca tcgaaagggc cacaaacggc aatcccatag caaagtaaac
    10321 agtaggcacc caacatacag ggcttatcgg ctttttattc atcagttagt tttttataat
    10381 aattccatcg gttaacaatt ccagtaagca aagataaggg atattaaaaa cataacccaa
    10441 gattacgaca agaagttgct ttcattattt aataatacaa ctcacccggg aaaactacta
    10501 acctctatca cccttttttt attaaacttt atcaatacaa cacacgcaaa gaagcaccga
    10561 agactttcat ccccgatgcc tctcgccccc ttatctacaa tctaaacacc tctattgctt
    10621 cacatataaa tttatctcag caaacccggt ataattatcc ggagtcagac agtttattct
    10681 gaattccttt acattcggga taggtggttc gatggccgca tattgcggat cagccccttt
    10741 aaaatttctg aaagtcaaga ctctcgggta agtaacccac tcggtttcac cctctttccg
    10801 aaccttaatc tcagcacttc tcagattata acccgatccg taggcactct gtttagtgac
    10861 cgaaaatccg gttaaggtaa caggtcggtc cagtaccgta ttccaccaac actctccggc
    10921 attagccact ccccatgtaa accaagtagt atttatctca ccgtcaatag ccagatgtgc
    10981 accatatttg gcatcatcat cggcataaac attgctgcaa cttacactcc acgcacttcg
    11041 atctacagcg gaccaattcc cgggtttcgt ataactggta taaagcacgc tggtataaat
    11101 ccggatataa accgtcttca tagatgtact gacagcctgt tcgtccatgc ccgtaactcc
    11161 tttaagcgcc acgggaagca catatccgtc aggattagtc aacttttcta tattcttcaa
    11221 aacgacctga aaagatgaat cggccactgt ctgtcccgtt tttaagacaa cttcacttgt
    11281 ttcaatggta taattatctt ggggcaacaa cttacatttc gtcttattgg cagaattgta
    11341 agtatccact ttcagcgtat ctactcccaa agcggcagtg acatcccgcg taaccggctg
    11401 tacggcacac aattgtattt caaaatcaga acggtcggca gtagaggaat tgctcacaca
    11461 atccaccact accgcagcac ccatttcggc ccccggtgca actcccgttc tgatatatat
    11521 cttttgatat ttgtccattt catcatcatc gttgctgcac gaagccaacg atacaaagcc
    11581 tgttatcagg cagattaagg tcacaaaatt caaatgtcta ttcatatctt atcttctttt
    11641 tacatagtta ttgcttatca aaacgaacat gctctttcca gacaagagtt cctcctgcca
    11701 ccaaatcgta tccgtgtccg gtacagtcga caaaggcatt tcccttacct tcatccattt
    11761 tccaatagcc tatcaggttc ggatcggcgg gcttcacggc aaaatacatg ttggactgaa
    11821 tttgcgtctg gctgattgcg ctcttccaaa gacgcacctg ggccatctga caattgttgc
    11881 ggaagtaact accgctcgaa accatgttca tcttgtcgaa tctaaccggg ccaccctttg
    11941 tctgcagagt cacgtcgagc actccgttga tataaatcga caataacccg gaagaattat
    12001 aaacgaaggc cagatgatac cacttattct tctcaaacaa agtcaccgta ttgacctgac
    12061 ttccaagtgt cttcacctgt aatgaattat aagggatcat agcgtcaccg aaacggatat
    12121 aaacctcgtg gtcgctgctg cccgaattaa atatagcctg attattaata tcgaatccgt
    12181 ccatctgtac ccaagcctcg agtgaccatt cattggttgt cactccccac aattcgtcct
    12241 tggcgggctt cacggcattg gtcgtattca taaacggtac agactgtatc agcggcttat
    12301 ccagcaaaat gataaacttc gacgaaaacc cgattgtgga caccggtccc tgaatttctg
    12361 tgagagatac cggaatagca tacaattctc cgttttcgtt tgaataaggt ttcactctaa
    12421 actcactggg gattgcgcta acatcgcctg ccgctatctt tatctctttg tcataagtaa
    12481 aatactgctc gggaaggact tcgtacgaag tttcattagc ttcattgtac tctttaagaa
    12541 tagaaggatc taccgtcagg acagcagtca cattttcggt tacaggctgt cccacacgta
    12601 cggtcagagt agttgttgtt acattttcag gatcaacggt aacctttgcc gaaccattct
    12661 cggatgcttc attcaaataa atcgcattgt cgataacctg gtaatcggca tcgttgcatc
    12721 ctgccaggat catcggcaga acgaaacagg caagcaaata ttgttttatt gttattcttt
    12781 tcataatcaa attctttaaa gtcattttac agcaggattc attattctga ttgcttcacg
    12841 caggtactta tattcgatgt cgcccggata gtcatattcc atgtgatagg tgcctactcc
    12901 acccttccgt acctgttttc cgtcaatagt cggagtccag cgtgccatgc cggcaagtgc
    12961 tctcattttg tttccgtaac gatctacata atcacctcct cctgtcggag cataagattc
    13021 gaaattctcc gtaacgatgt acatattagc cactttctcc ggaggaagta ttcctttaaa
    13081 gttggcaatc gtaccagcca gacgtctgtc aagattagcg tcggaattac ccgcaaggtt
    13141 agagtatgcc tgcacaatga aatagtcaaa gtaaggcccg gtttccggat gaatactttg
    13201 aggctcgcca tcaatcacaa gtaaccgtcc cgtacccgat ttaggtccga ttcttt
//
