LOCUS       c00423_gnlPro..        13647 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DOOGDFOH_648.
ACCESSION   c00423_gnlPro..
VERSION     c00423_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 22:26:50
            Original ID  :: gnl|Prokka|DOOGDFOH_648
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13647
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13647
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7168:12269]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7169..12269
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..13647
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13647
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(3..548)
                     /locus_tag="ctg423_1"
                     /transl_table=11
                     /translation="MTTKYTYKEIWIIAYPILISLIMEQLIGMTDTAFLGRVGEVELGA
                     SAIAGVYYLAIFMMAFGFSIGAQILIARRNGEQQYQAIGPIFYQGVYFLLSLAVVAFTL
                     SLCFSPHILKKVISSEHIYDASISYINWRVFGFFFSFVGVMFRAFFVGTTQTKTLTLNS
                     VVMVLSNVVFNYILIFGKF"
     CDS             complement(637..2493)
                     /locus_tag="ctg423_2"
                     /transl_table=11
                     /translation="MDKNTITGLVLIGILLVGFSFLSRPSEEQIAAQKRYYDSIAVVQQ
                     QEEALRAKTEAALANEKEETAADSASLFFSATKGKEAFTTIQNNLVEITLDNKGGRVYS
                     ALLKNYMGQDKKPVVLFNGSDASMNFNFYNKKGALQTKDFYFEAVNKTDSSVTMRLAAD
                     SASYIDFIYTLKPDNYLMSFVIKATGMDGKLAASTNYVDISWSQRARQIEKGYTYENRL
                     ADLTYKYTGDDVDNLSASKDDEKSVSERLDWIAFKNQFFSSVFIAEQDFEKTTVKSKME
                     KQGSGYIKDYSAEMSTFFDPTGKQPTDMYFYFGPNHYKTLTALDKGREEKWELNNLVYL
                     GWPLIRWINKWITINVFDWLSGWGLSMGIVLLLLTIMVKIVVFPATWKTYMSSAKMRVL
                     KPKIDEINKKYPKQEDAMKKQQEVMGLYSQYGVSPMGGCLPMLLQFPILMALFMFVPSA
                     IELRQQSFLWADDLSTYDAFITFPFHIPFLGNHLSLFCLLMTVTNILNTKYTMQQQDTG
                     AQPQMAAMKWMMYLMPIMFLFVLNDYPSGLNYYYFISTLISVVTMIILRRTTDENKLLT
                     ELEAKKKDPKQMKKTGFAARLEAMQKQQEQLAKERANKQNKK"
     CDS             complement(2542..4143)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg423_3"
                     /sec_met_domain="GATase (E-value: 8.8e-56, bitscore: 178.5,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGETKYIFVTGGVASSLGKGIISSSIGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLGIQTTKANNITTGRIYKSVIDKE
                     RRGDYLGKTIQVIPHITDEIKRNVKLLGNKYKFDFVITEIGGTVGDIESLPYLESIRQL
                     KWELGQNALCVHLTYVPFLSAAQELKTKPTQHSVKELQSLGVQPDILVLRTEHDLNTNL
                     RKKVALFCNVAENAVVQSIDASTIYEVPLLMQEQGLDETILQKMGLPVGERPPLGPWKD
                     FLNRRANATETVTIAMVGKYVELQDAYKSILESLSQAATYNDRKVKIEYVSSEHLTPDN
                     VDEQLGHVNGVVICPGFGSRGIEGKFVAAKYTREHNIPTFGICLGMQCMAIEFARNVLG
                     YADANSIEMDEKTKHNVIDIMEEQKAITNMGGTMRLGAYECVLKKDSKVYEAYKEEHIQ
                     ERHRHRYEFNNDYRKQFEEAGMKCVGINPESDLVEIVEIPTLKWYIGTQFHPEYSSTVL
                     HPHPLFVSFIKAAIDK"
     CDS             complement(4334..4441)
                     /locus_tag="ctg423_4"
                     /transl_table=11
                     /translation="MNLYNNSAVLLERALSLRTIQIELRTAFPRLDSAS"
     CDS             4527..5960
                     /locus_tag="ctg423_5"
                     /transl_table=11
                     /translation="MKTSHISTLAFAILFSSSVMAQKTNKPVSETVQSEVKADTLSETL
                     QQYLVLKLNLDGPKPKIDTVSILYNKYIGELEYLNDPSVPMRYIKTDPDYYRLFVPLTY
                     YNSPIAEYSTMHWKFKEPFVTPSLSSQLLPPYDTLQFSKAERASRLVNVALMDLYLNHP
                     NLVVNTEDHIMSRKLYHGDKKIEVPKTEVKSLFRADKVEDNVGEAEMVISKPNWWVTGG
                     NGSLQITQNYISDNWYKGGESNNAVMANLQLFANYNDREKVQFENLFEAKLGFNSSPSD
                     EYHKYLVNTDQLRLYSKLGIQAANNWYYTITGEFKTQFVKGYKANSEELVAAFLAPADV
                     IVSVGMDYKLKKKKFNLSVFMSPLTYNLRYIGNKNVDETKFGLDKGKCSKNDFGAQVQP
                     TISWTIIPSIVVDSRLNYLTNYKWVRVEWENTFNFVLNRYLSTKLFVHARFDDSAKPTT
                     GSSYFQLKELLSFGLNYKW"
     CDS             6089..6493
                     /locus_tag="ctg423_6"
                     /transl_table=11
                     /translation="MIKQDYLIRMIQEIISLIVNAILNKKKFRKDEWTEYDCLTRQILG
                     VSQEELLSMSLDEMIDCYEGDPNRMGKIELAAVTLLKVSDEAESDILQKSKLRQDGLSL
                     LKYVQKESSTFSIQRTNLIRMIEINESLKM"
     CDS             6744..7163
                     /locus_tag="ctg423_7"
                     /transl_table=11
                     /translation="MTNIITHQGIVENISGSQVFVRIIQTSACSTCSVKGHCSSADSKE
                     KVIEVTDTSSAWKIGDEVTIIGATSMGMQAVLLAFLIPLFLLIFGLFIFKTVLHSELYG
                     AFAALAVLIPYYYIIWLNRTRLKQKFSFTIKPINN"
     CDS             7169..8041
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 36.6; E-value:
                     1.8e-11)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg423_8"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-12, bitscore: 38.4,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3e-09, bitscore: 26.5,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.6e-09, bitscore: 27.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 7.3e-09, bitscore: 25.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 2.9e-09, bitscore: 27.4,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 3e-11, bitscore: 32.8,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 8.8e-07, bitscore: 19.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAVLYVASKKFAVYEDPRIAQVSEVLP
                     QANCGGCGYPGCSGFADACVKAGSLEGKFCPVGGQPVMSQVASILGLDAGTAEPMVAVV
                     RCNGTCTNRPRTNMYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACVKACPKAIIELRAKGKKSRRVYVSCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDYNKCKSCRKCVEVCPQHTIIELNFPPRKPKEEMPV
                     AEAAKTAEA"
     CDS             8078..9415
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg423_9"
                     /sec_met_domain="Fer4_7 (E-value: 1.2e-09, bitscore: 28.7,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 9.6e-17, bitscore: 50.6,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.4e-51, bitscore:
                     163.6, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1e-31, bitscore: 98.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.8e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIVTAEVPAKAVILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEANGFVSAAIHSSVSGKVAKIDSIVDASGYAKPAIFIDVDGDE
                     WEESIDRSPELVKECELTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEVMVGVAILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSVAQPSNFLARIGTPMQQLIDACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNRKEAKRGEVQNCIRCAKCVSACPMGLEPYLLSALAENTEFERM
                     ESERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             9421..10413
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg423_10"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 8.1e-120,
                     bitscore: 389.4, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFIVSLVYFGLGA
                     LIVTATSVIACLFFEWAIGKFLLKKETTTICDGSAVITGVLLAFNLPSNLPVWIIILGA
                     LFAIGVGKMSFGGLGNNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTAATPL
                     ALMKQAIHGDVSAFGQLPDAWSLFIGNNGGCLGEVSAAALILGLLYMLWKRIITWHIPV
                     SILVTVFVFSGIMHLANPEAYVSPVIQLLSGGLMLGAIFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             10440..11078
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg423_11"
                     /sec_met_domain="FMN_bind (E-value: 1.7e-24, bitscore:
                     76.2, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKGPIAEANAKTLNEALKEVLPE
                     FTNNPVAECDTVFSEKDGKKIVDFIIYPAKNGDQWVGTAVEAKSMGFGGELKVLVGFDA
                     EGKIYNYSLLSHAETPGLGSKAADWFKEGNKGSIKGMNPGEQPLTVSKDGGQVDAITAS
                     TITSRAFLNAVNAAYGAYKGNGGANGTTGASQKVVQKSETGIVDSVVIK"
     CDS             11096..11683
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg423_12"
                     /sec_met_domain="Rnf-Nqr (E-value: 4.9e-71, bitscore:
                     228.2, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVLMNGIVKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNALSSMFDGIGMGLGFTIALTLLGAVREFLGTGKVFNLSIIP
                     EEYGMLVFVLAPGAFIALGYLIALINSLKKAN"
     CDS             11697..12269
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg423_13"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.9e-64, bitscore:
                     205.7, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVDTALGMSAAVA
                     FVLTIATIVTFLIQKFVLDAFGLQYLQTITFILVIAALVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKIP
                     EGMKGTPIALITAGLLAMAFMGFSGVV"
     CDS             12474..13508
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg423_14"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.7e-53, bitscore:
                     172.0, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSNADVVDN
                     IEKVSGIRPVFEKLDCLDFDGLDAVFNKYKGIKAIIHFAASKAVGESVEKPLLYYRNNL
                     VSLINLLELMPKHGIEGIVFSSSCTVYGEPDELPVTENAPIKKATSPYGNTKQINEEIV
                     RDTVASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIARILEKKQKDKVETFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDYANNELGWKAQETLEDTLRSAWAWQLKLRE
                     RGIQ"
ORIGIN
        1 ccgaacttac cgaaaatcag tatgtagttg aacaccacat tggataatac catgaccaca
       61 gagttcagtg tcagggtttt ggtctgagtt gtacccacga agaatgcacg aaacattact
      121 ccgacaaagg agaagaaaaa gccgaagacc ctccagttga tgtagctgat ggacgcatcg
      181 tatatatgct ccgagctaat gacctttttc agtatgtgcg gtgagaagca cagcgaaaga
      241 gtgaatgcta ccactgcgag tgaaagcaga aagtagacac cctgataaaa gatgggcccg
      301 atagcctggt attgctgttc accgttacga cgggcaatca ggatttgtgc acctatactg
      361 aatccgaatg ccatcataaa aatagccaga tagtatacac cggcaatggc cgaggctccc
      421 agttcgactt cgcccacacg tcccagaaaa gcagtgtcgg tcatgcctat cagctgttcc
      481 atgatcaggc tgatcaggat ggggtaggcg ataatccata tttctttgta tgtgtattta
      541 gtagtcatgt tgtaatctgt tcaataaagg aaaagaaagc cggacaaaca tacactgctt
      601 gtccggctct tcggtattta agctgatttc tatctcttat ttcttattct gcttattagc
      661 ccgttctttt gccaattgtt cctgttgttt ttgcatagct tccaggcgtg cggcaaatcc
      721 ggtcttcttc atctgtttcg gatctttctt cttagcttcc agttcggtaa gcaatttgtt
      781 ttcgtcagtt gtccggcgca atatgatcat ggttactaca ctgatcagag tcgaaataaa
      841 gtagtaatag ttcaatcccg aaggatagtc gttcaagacg aagaggaaca tgatcggcat
      901 caggtacatc atccacttca tcgcagccat ttgcggctgg gcacccgtat cctgctgttg
      961 cattgtgtac ttcgtattca ggatgttggt aacagtcatc agcaagcaga acaaactgag
     1021 gtgattaccc aagaatggaa tatggaacgg gaaagtgatg aatgcgtcat aagtcgacaa
     1081 gtcatccgcc caaaggaaac tctgctgacg aagttcgata gcactcggta cgaacatgaa
     1141 caatgccatc aggataggga attgcaacaa catcggcaga cagccaccca tcgggcttac
     1201 accgtactgg ctgtacaatc ccatcacctc ctgctgtttc ttcatcgcat cttcctgttt
     1261 ggggtatttc ttgttgattt catcgatttt cggtttcagc acccgcattt tggctgatga
     1321 catataggtc ttccatgttg ccgggaaaac gactattttc accatgatgg tgagtaacaa
     1381 cagaacgata cccatactta atccccagcc ggacaaccag tcgaatacgt tgatggtgat
     1441 ccatttgtta atccaacgaa tcagcggcca gcccagatat accaggttgt taagttccca
     1501 tttctcttca cgtcccttat ccaacgcagt caacgttttg tagtggttcg ggccgaagta
     1561 gaaatacata tcggtaggtt gtttgccggt cggatcaaag aacgtactca tctcggcgga
     1621 atagtctttt atgtaaccgc ttccctgttt ctccattttc gatttaaccg tagtcttttc
     1681 gaaatcctgt tctgcgatga atacggaaga gaagaactga ttcttgaaag cgatccagtc
     1741 cagacgttcc gaaacggact tttcgtcgtc tttacttgcc gaaaggttat ccacatcatc
     1801 accggtgtat ttgtaggtga ggtctgccaa acggttttcg taagtatatc ccttttcgat
     1861 ctggcgggca cgttgtgacc atgagatgtc cacatagttt gtgctggcag ccaattttcc
     1921 gtccattccc gtagctttga tcacaaagct catcaggtag ttatcaggtt tcagtgtata
     1981 aatgaaatcg atatagctgg cactgtcggc agctagacgc atcgttacac tgctatctgt
     2041 tttattgact gcttcaaaat agaagtcttt tgtctggagg gcccccttct tgttatagaa
     2101 gttgaagttc atggaagcat cgctgccgtt gaacaacaca accggtttct tatcctgtcc
     2161 catgtagttt ttcaacaggg cagagtaaac acggccgcct ttgttatcca gagtgatttc
     2221 taccaaatta ttctggatag tagtaaacgc ctctttacct ttggtggcac tgaagaagag
     2281 cgatgctgag tcggctgctg tttcttcttt ttcgttagcc agcgcagctt cggttttggc
     2341 tctcagtgct tcttcttgct gctgtaccac ggctatagag tcataatacc gcttttgagc
     2401 ggctatttgc tcctcgctgg gacggctcag aaaactgaat cctaccagta atatacctat
     2461 taaaacgagg cctgtgatgg tgtttttatc cattctcttt tttaagtgat taatgattaa
     2521 taatctatac gataacgatc tttacttatc gattgcagcc ttgatgaacg acacgaacaa
     2581 cggatgcggg tgtagtacgg tactgctgta ttccggatgg aactgtgttc cgatgtacca
     2641 tttcaatgta ggaatctcta caatttctac caagtcggac tcggggttga tacctacaca
     2701 cttcatgccg gcctcttcga attgtttgcg atagtcgttg ttgaattcgt agcggtggcg
     2761 atgacgctcc tgaatgtgtt cttctttgta ggcttcgtat accttagagt ctttcttcaa
     2821 tacacattcg taagctccca gacgcatggt acctcccata ttggtgatgg ctttctgctc
     2881 ttccatgatg tcgatcacgt tgtgcttggt cttttcatcc atttcaatgg agttggcatc
     2941 ggcataaccc aacacattac gggcaaactc gatagccata cattgcatac ccagacagat
     3001 accgaatgtc ggaatgttgt gttcgcgggt gtatttggca gctacgaact taccttcgat
     3061 accgcgtgaa ccgaatcccg gacagataac tactccgttt acatgtccca attgttcgtc
     3121 tacattgtcc ggagtcagat gttcggatga tacatattct atttttactt tacggtcatt
     3181 gtaggtagca gcttgtgaca aggattccag aatagatttg taggcatcct gcaattcaac
     3241 atatttacct accattgcaa tggttactgt ttcagttgca ttggcacgac ggttcaggaa
     3301 gtctttccaa ggacccaacg gcggacgttc gcctacaggc agacccatct tttggagtat
     3361 ggtttcgtcc aggccttgct cttgcatcaa cagaggtact tcataaatag ttgaagcgtc
     3421 gattgactga acaactgcgt tttcggctac attacagaac agagcgacct tcttgcgcaa
     3481 gttggtattc aggtcatgtt cggtacgtag caccaggata tccggctgta caccgagtga
     3541 ttgcaactct tttacggaat gttgagtcgg tttggttttt aactcttggg cggcggacag
     3601 gaaaggtaca taagtcaggt gtacacacaa ggcattctga cccagttccc atttcaactg
     3661 acgaatactt tccagataag gcaaagattc gatatcacct actgttccgc caatttctgt
     3721 gattacaaag tcgaacttat acttgttacc cagtaacttg acgttacgtt tgatttcatc
     3781 ggtgatatga ggaatcacct gaatggtttt ccccaaataa tctccacggc gttctttatc
     3841 gatgacgctc ttatagatac ggcctgtcgt gatgttgttg gccttcgttg tctggatgcc
     3901 caggaaacgt tcgtagtgtc ctaagtcaag atcggcttca tggccgtcta cagtcacgta
     3961 gcattctccg tgttcataag ggttcaatgt tcccgggtca atgttgatgt acgggtcaaa
     4021 cttctggata gttactttat aacctcttgc ttgcagcaat ttaccgatgg aagatgaaat
     4081 gatacctttt cctaaagaag aggcaacacc accggtgacg aaaatatact ttgtttctcc
     4141 cacagctata actgttttaa taatttgttt ctaaatcctt tgatttgaat cttaaaaacc
     4201 gcaaaattac aaaaaaatgg ggaagaacgg atgctttcta caaaacaaat ttattaaaaa
     4261 atgcaattcc gggtaccgaa atgtttgaac gacaaacagt cacatgtttg ccggcatata
     4321 agcacgcctt tattcaactt gcactatcga gccgggggaa ggcggttctc agttcgatct
     4381 gtattgttct gagagataat gcacgttcca ataaaacagc tgaattgttg tatagattca
     4441 tttgataggt tattcctatt aaaatcgagc aaattttatg taatctaaac tatttaatgt
     4501 aaatttgccc caaatttgtt ataaaaatga agactagtca catctcaaca ttagcatttg
     4561 cgatcctgtt ttcttcgtca gtgatggcgc agaagacgaa caaaccggtt tctgaaacag
     4621 tgcagagtga agtgaaagca gatacacttt ccgagacgct tcaacagtac cttgtcctga
     4681 aactgaatct ggatggtccg aagcctaaga tagatacggt gtccatctta tataataagt
     4741 atataggaga gttggaatat cttaatgatc cttctgtacc catgcgttat attaagacag
     4801 atccggatta ctaccgactg tttgtaccgc tgacttatta taactctccc atcgcggaat
     4861 attctaccat gcactggaag tttaaggaac cttttgttac tccctctctt tcttcgcaat
     4921 tattgccgcc gtatgacaca ttgcagtttt ctaaagctga gagagcttcc cggctggtga
     4981 atgttgcttt gatggatcta tatctgaatc atcctaattt agtcgttaat accgaagatc
     5041 atatcatgag ccgtaagttg tatcatggcg ataagaagat tgaagtcccg aaaacagaag
     5101 tgaaaagcct gttccgtgcg gataaggtgg aagacaatgt gggtgaagcg gaaatggtga
     5161 tctccaagcc caattggtgg gtgacaggag gtaacggttc gcttcagatt acccagaact
     5221 atatttcgga caactggtac aagggaggtg agagcaataa tgccgtaatg gccaatctgc
     5281 agttgtttgc taactacaat gaccgtgaga aagtacagtt tgaaaatctg ttcgaagcta
     5341 aattaggatt caattcttct ccgtcagacg aatatcataa atacctggtt aataccgacc
     5401 agttgcgttt gtattctaaa ttaggtattc aggctgccaa taattggtac tatactatta
     5461 caggagagtt taaaacccag ttcgtaaagg gatataaggc taacagtgaa gagttggtag
     5521 ctgctttcct tgctcctgca gatgtgatag tcagtgtcgg tatggactat aagttgaaaa
     5581 agaaaaaatt caatctttct gtattcatgt ctccgttgac ttataacctt cgttatatag
     5641 gtaacaaaaa cgtggacgaa accaagtttg gattggataa aggcaaatgc tcgaagaatg
     5701 acttcggtgc acaggttcaa cctactattt catggactat tattccgtct attgtagtcg
     5761 attcccgttt gaactatctg acgaactata aatgggtgcg tgtagagtgg gagaatactt
     5821 tcaacttcgt attgaaccgt tatctttcta ctaaactatt tgtacatgca cgctttgacg
     5881 acagtgcgaa gccgactact ggcagcagtt atttccagct gaaggagttg ctaagttttg
     5941 gtctgaatta taaatggtaa tcgggaataa ttgacataat gtaaatatat gaaatagggg
     6001 ccgactggaa tcttcagtcg gctctcttct ttccggtgag gttaattctc tccgtggtaa
     6061 gtaagttcta attcaaaaag aggatattat gattaaacaa gactatctga tacggatgat
     6121 tcaggaaatc atttcgttaa ttgtaaatgc gatattgaat aaaaagaagt tccgtaagga
     6181 tgaatggact gaatatgatt gcctgacgag acagatttta ggagtttctc aagaggaatt
     6241 gttaagtatg agcctggatg aaatgattga ctgttatgaa ggagatccta atagaatggg
     6301 gaagatagaa ttggcggccg tgactttgtt gaaagtttcg gacgaggcgg aatctgatat
     6361 tttgcaaaag tccaaattac gtcaggatgg gctttccttg ctaaaatatg ttcagaaaga
     6421 aagcagtacc ttttcaattc agcggacgaa tttgattcgg atgattgaga ttaatgaatc
     6481 tcttaaaatg tagaaaggga aataaacaga aagtgataaa agaattggtt tttgtttcta
     6541 atttctttga aaatatcaga agatgataac attttcttag taaagcaggt gaaaagcctg
     6601 ctttttctgt atccataccc gattgataga gcaaaaatta ctttaaaaag acttcatatt
     6661 gcactataaa aaacattcaa atacttcgta attttcaaac ttatgcttaa atttgccgca
     6721 atttgtaatg tgcagtttgc aaaatgacta atataataac tcatcaaggt attgtggaaa
     6781 acataagtgg ttctcaggtt tttgtgagga tcatccagac atcggcttgc tcgacttgca
     6841 gtgtcaaggg acattgctct tcggcagata gcaaggagaa ggtaattgaa gttaccgata
     6901 cttcgtctgc atggaagata ggggacgagg tgacgattat tggtgccacc tccatgggca
     6961 tgcaagcggt tcttctggct tttctcattc ctctctttct tttaatcttt ggccttttca
     7021 ttttcaagac agttcttcat agtgaactat atggggcatt tgctgctttg gcggtgctta
     7081 ttccttatta ttatataata tggttgaaca gaactcggtt gaaacaaaaa ttttctttta
     7141 ctataaaacc aataaataac taaaaattat gaatttgatt ctgattgcag tgatttcttt
     7201 gggagctatt gcgcttgtat tggctgcagt attgtatgtt gcttctaaga aatttgccgt
     7261 gtacgaagac ccacgaattg cccaggtatc cgaagtgttg cctcaggcta actgcggtgg
     7321 atgtggttat ccgggttgca gcggatttgc cgatgcttgc gtcaaagccg gttcgctgga
     7381 aggtaagttt tgtccggtgg gtggacagcc tgtgatgtct caggttgcct ctattctcgg
     7441 attggacgcc ggaactgcag aaccgatggt tgcagtggtt agatgtaacg gaacctgcac
     7501 gaaccgtccg cgtacaaata tgtatgacgg tgcaaagagc tgtgctattg ctgcttcgct
     7561 ttatggcgga gagaccggct gtagctatgg atgtttggga tgtggcgact gtgtggctgc
     7621 ctgccagttc gatgctattc acatgaatcc ggaaacagga cttcctgagg tggatgaaga
     7681 aaagtgtacg gcttgcggag cttgtgtaaa agcctgtccg aaagcgataa tcgaacttcg
     7741 tgccaaaggt aagaaatcgc gtcgtgtata tgtatcttgt gtcaacaaag acaaaggggc
     7801 tgtcgcacgc aaagcctgta cggtaagttg catcggttgt ggtaagtgtg tcaaaacttg
     7861 tccgttcgag gcaattacac ttgaaaacaa tctcgcttac atcgattaca ataaatgtaa
     7921 gtcttgtcgc aagtgcgttg aagtttgtcc gcagcacact atcatcgagt tgaatttccc
     7981 tcctcgtaaa cctaaagagg aaatgcctgt tgccgaagct gccaaaactg ccgaagctta
     8041 aaaaaacgag taataaacag ataaaataca gaattgtatg ttgaagacat tttcaattgg
     8101 tggtgttcat ccacacgaaa ataaactctc agcacatcaa cctattgtta cggcagaggt
     8161 tccggcaaaa gctgtgatac tgctggggca gcatatcggt gcgcctgcta agcctattgt
     8221 ggcaaaaggt gatgtggtga aggtgggcac taaaatagcc gaagctaatg gctttgtttc
     8281 ggcagccatt cactcttctg tcagtggtaa agtcgctaag attgactcta ttgtcgatgc
     8341 gagcggttat gctaaacctg ctatttttat tgatgtagac ggggatgaat gggaagagtc
     8401 tatcgatcgt agtcctgaat tggtaaaaga gtgcgaattg acttcggaag agattgtgaa
     8461 gaagatagca gatgcaggca ttgttggttt gggaggagct tgtttcccaa ctcaagtcaa
     8521 actttgtccg cctccttcat ttaaagcaga atgcgtgatt atcaacgctg tagagtgtga
     8581 accttacttg acagccgacc atcaactgat gttggagcat gccgaggagg taatggtagg
     8641 ggtggctatt ctgatgaagg cggtgaaagt caataaggct tttataggta tcgaaaacaa
     8701 taaacccgat gctatccaac tgatgacgaa agtcgcatcc agttatgccg gtattgaagt
     8761 tgttcctttg aaagtgaaat atcctcaagg gggtgagaag cagttaatcg atgctattac
     8821 gaagcgccag gttgcaagcg gcgcattacc tatctctaca ggagcagttg tgcagaatgt
     8881 aggtactgca tttgccgtat atcaagctgt acagaaaaat aagcctttgt ttgagcgtgt
     8941 cattacggtg accggtaagt ctgttgccca gccttctaac tttttggcgc gtattggtac
     9001 tccgatgcag cagttgatcg atgcctgtgg cggtttgccg gaggataccg gaaaaataat
     9061 tggcggtggt ccgatgatgg gtaaagcatt ggttaatact gatgtgccca ctgctaaagg
     9121 aagttctgga attttgatta tgaaccggaa agaggcaaaa cgcggagaag tacagaactg
     9181 cattcgttgt gcaaagtgtg tgagtgcctg cccgatggga ctggagccgt atctgctttc
     9241 cgctttggct gagaacacag aatttgaaag aatggaatca gaaagaatca tggattgtat
     9301 cgagtgtggc tcttgccagt tcacttgtcc tgccaatcgt ccgttactcg actactgtcg
     9361 tctgggtaag gggaaagtag gagctatgat tcgtgcacgt caagctaaaa aataataagt
     9421 atggaaaata aattaattgt atcattatcg cctcacgttc atggtggaga cagcgtacaa
     9481 aagaatatgt acggtgtgct gattgcgctg attcctgcct ttatcgtttc gctcgtatat
     9541 ttcggactgg gtgcactgat tgtcacagct acttctgtga tagcctgttt gttttttgaa
     9601 tgggcaatcg gtaagttctt gctgaagaaa gaaaccacta ctatttgtga cggttctgct
     9661 gtcatcacgg gagtgttgct ggcgttcaat ctaccgtcta acttacctgt atggattatt
     9721 attttaggtg ctttgtttgc tattggtgtc ggtaagatgt catttggcgg cttggggaac
     9781 aatccgttta acccggcact ggcagggcgt gtgtttctgt tattgtcatt cccggtacag
     9841 atgacttcct ggccggtggt cggtcagttg actgcttata ccgatgctac tactgccgcc
     9901 actcctttgg cattgatgaa acaggctatt catggggatg tctcggcttt tggtcaactg
     9961 cccgatgcct ggagtctgtt tattggtaac aatggtggat gtctgggtga agtgagtgct
    10021 gctgccctga ttttgggtct tctttatatg ttatggaaga gaatcattac atggcatatc
    10081 cctgtatcca ttctggttac tgtatttgta ttttccggta tcatgcatct ggcaaatccc
    10141 gaagcttatg tttctccggt gatccagttg ctttcgggag gtctgatgct gggtgctatc
    10201 tttatggcaa cagactatgt cacttctccg atgagtaaaa aaggtatgtt gatttatggt
    10261 gtctgcatcg gtttgctgac ggttgttatc cgtctgtttg gtgcatatcc ggaaggtatg
    10321 tcgtttgcta ttctgattat gaatgcattc actccgctaa tcaatacgta ttgcaaacca
    10381 aaacgctttg gggaggtagc gaagaagaaa tgaaaaagtt agaatcatca ttgaaaaata
    10441 tgttgctggt actcaccgga gtaacagcta tctcggtagc tttgctggct tatgtgaatg
    10501 agttgactaa aggtcctatt gcagaggcga atgcgaagac attgaatgaa gctttaaaag
    10561 aagttttgcc cgaatttaca aataatccgg tcgcagagtg tgataccgtg tttagtgaga
    10621 aagatggcaa gaagattgtt gactttatca tttatccggc taaaaacgga gatcaatggg
    10681 taggaacagc agtagaagcc aagtcgatgg gatttggcgg agaattgaaa gtacttgttg
    10741 gttttgatgc tgaaggtaaa atctacaact attctttgtt gtcacatgcc gaaactccgg
    10801 gacttggttc caaggcggct gactggttca aagaaggaaa caaaggtagc attaagggaa
    10861 tgaatccggg tgagcaaccg ctgactgtaa gtaaagacgg cggacaggta gatgccatta
    10921 ctgcttctac tatcacctca cgtgcatttt tgaatgctgt gaatgctgcc tatggtgctt
    10981 ataaaggcaa tggtggtgct aatggtacga ccggtgcttc gcagaaagtt gtgcagaagt
    11041 ccgaaactgg gattgtcgat tcagtagtca ttaaataaga aaggagtata aagatatgaa
    11101 taactttaaa gtattaatga atgggattgt taaagagaat ccgacatttg tgctcctgct
    11161 tggtatgtgt cctacactcg gtacgacttc ctcggccatt aatggtatgg gcatggggct
    11221 tgccactatg tttgtattga tctgttccaa tgtagtgatt tcattgataa agaacctgat
    11281 tccggacatg gtgcgtattc cgtcattcat tgtagtcatt gcatcttttg tgactttgct
    11341 tcagatggta atgcaagcat atgtacccgg actgtacgct acattgggac tttttattcc
    11401 attgattgtt gtgaactgca ttgtgttggg acgtgcagaa gcatttgcag ccaagaataa
    11461 tgcactttct tctatgttcg acggaatcgg tatgggattg ggctttacaa ttgcccttac
    11521 attgctggga gctgttcgtg agttcctggg tacaggcaag gtattcaact tgtcaatcat
    11581 tccggaagaa tacggtatgc ttgtctttgt gcttgctccg ggtgcgttta tcgcattggg
    11641 atatctgatt gcgttgatta acagccttaa gaaagcgaat taaaatataa acgattatgg
    11701 aatatatatt gatatttatc tcggcaatct ttgttaataa cattgtgttg tcgcaatttc
    11761 tgggaatctg tcctttcttg ggtgtttcca agaaagtgga tactgcattg ggtatgagtg
    11821 cagcggtagc tttcgtgctt accattgcta cgatcgtaac gttcctgatc cagaagtttg
    11881 tactcgatgc tttcgggttg cagtacttgc agactatcac gtttatcttg gttatcgctg
    11941 cattggtgca gatggtagaa attattctga agaaagtttc tcccgcactt tatcaggcat
    12001 tgggcgtatt ccttcccttg attacaacga attgttgtat cttgggtgtg gcaattcttg
    12061 ttatccaaaa agattatgac ctactgacgg gtgttgtata tgcattctct actgctattg
    12121 gtttcggtct ggccctcgta ctttttgccg gactccgtga gcagatgagt cttgtgaaaa
    12181 ttcccgaagg aatgaaaggt actccgattg ctttaattac agccggattg ctggctatgg
    12241 catttatggg attctccgga gttgtataaa tcctgacgac aaacaactga aggatggagc
    12301 ggcggatagg ctaccgatgg ggtagttctt ccgccgcttt ttctgttatt ttgtcttaat
    12361 ccctgtttgc gttatgaaat aatattcgtt ttttgtgcat ttatctaaat taattttgtt
    12421 acatttgcaa acactttaca agtaaaccga aaaaactaac cattatacac gttatgaaag
    12481 aaagaatttt agtaacaggc ggaaccggat atatcggctc tcatactgtg gtagagctgc
    12541 aaaacagtgg atacgaagta atcatcattg ataatttatc taattcaaat gctgatgtcg
    12601 tagataatat cgaaaaggta tcaggtattc gtcctgtttt cgagaaactg gattgcttgg
    12661 attttgacgg tttagatgcc gtgttcaata aatataaagg tattaaagcg attatccact
    12721 ttgcggccag caaggcagta ggtgagtctg tagaaaaacc attgctttat tatcgcaaca
    12781 acctcgtttc tttaattaac ttgcttgaat taatgcctaa acatggcatt gagggcattg
    12841 tattctcttc ttcatgtact gtatatggtg aaccggatga attgcctgta acagagaatg
    12901 ctccgataaa gaaagctact tctccttatg gaaataccaa acagattaat gaagagattg
    12961 ttagagatac agtagcttcc ggtgctccga ttaatgcaat tttactgcgt tattttaatc
    13021 cgattggtgc tcatccgaca gcattgttag gagaacttcc taatggcgta cctcaaaatc
    13081 ttattccgta tttaactcag actgctatcg ggattcgcga aaaattgagt gtcttcggtg
    13141 atgattatga tacacctgac ggttcatgta tccgtgactt tatcaatgta gtcgatcttg
    13201 ctaaagcaca cgtaattgct attgcacgta ttcttgaaaa gaaacaaaaa gataaagttg
    13261 aaactttcaa tatcggtaca ggacgtggag tttcagttct tgaactgatc aacggatttg
    13321 agaaagctac cggcgtaaaa ctgaactatc agattgttgg acgtcgtgcc ggtgatattg
    13381 aaaaggtatg ggctaaccct gattatgcga acaatgaatt gggttggaaa gctcaggaaa
    13441 ctctggaaga tacactgcgt tctgcttggg catggcagtt gaaacttcgt gaaagaggta
    13501 tccaataaat aagaatattg ttttaattaa catataagac atgaacaaat gtttttatac
    13561 atttgtttat aggatgcaaa tcggcctgaa gctgtttatg tgtatgtgaa tatccataat
    13621 tagtacttat gcctccccgg catagac
//
