LOCUS       gnlProkkaBOKOFBJE_52    2526 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BOKOFBJE_52.
ACCESSION   gnlProkkaBOKOFBJE_52
VERSION     gnlProkkaBOKOFBJE_52
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 03:14:18
            Original ID  :: gnl|Prokka|BOKOFBJE_52
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2526
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     aSDomain        1..1089
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg35_1_AMP-binding.1"
                     /evalue="1.70E-98"
                     /label="ctg35_1_AMP-binding.1"
                     /locus_tag="ctg35_1"
                     /protein_end="363"
                     /protein_start="0"
                     /score="321.7"
                     /specificity="substrate consensus: Asn"
                     /tool="antismash"
                     /translation="MNRKANALAWELISLGVQPNDRVAIMTTLEAETIIGILGVLKSGA
                     AYVPIDPATPKERIEHILNDAAPKVILTREKTMETEVPFISMNLEDLGEKETNPACAVE
                     KSDIAYLIYTSGTTGKPKGVAVTRGNLDHYLSYADQEYQKEACTTVLMTSLSFDLSVTS
                     LFLPLISGGSLLLKGGDTEERLRAALKDNRVTFLKLTPSHLKMLETYADGVDVPNLETL
                     IVGGEEFTTDTAWKTQKLLGESVKIHNEYGPTETTVGCCDYVYSSEKDKGLSVGIGHPI
                     ANMQLYILNEMELCGVGVPGELCIAGDGVAKGYLNQPELTAEKFIDNPYGEGKLYRSGD
                     LARWLPNGEMEYLGRIDEQVKIR"
     aSModule        1..1611
                     /complete
                     /domains="nrpspksdomains_ctg35_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg35_1_PCP.1"
                     /locus_tags="ctg35_1"
                     /monomer_pairings="Asn -> Asn"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     protocluster    1..2526
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:2526]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..2526
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..2526
                     /SMILES="NC(CC(=O)N)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2526
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             1..2526
                     /NRPS_PKS="Domain: AMP-binding (0-363). E-value: 1.7e-98.
                     Score: 321.7. Matches aSDomain:
                     nrpspksdomains_ctg35_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (470-537). E-value: 1.7e-19. Score:
                     61.7. Matches aSDomain: nrpspksdomains_ctg35_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (553-834). E-value:
                     4.8e-94. Score: 306.6. Matches aSDomain:
                     nrpspksdomains_ctg35_1_Condensation_LCL.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     305.9; E-value: 7.1e-93)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_1"
                     /sec_met_domain="AMP-binding (E-value: 2.7e-109, bitscore:
                     351.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.6e-16, bitscore:
                     46.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5.6e-79, bitscore:
                     251.4, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRKANALAWELISLGVQPNDRVAIMTTLEAETIIGILGVLKSGA
                     AYVPIDPATPKERIEHILNDAAPKVILTREKTMETEVPFISMNLEDLGEKETNPACAVE
                     KSDIAYLIYTSGTTGKPKGVAVTRGNLDHYLSYADQEYQKEACTTVLMTSLSFDLSVTS
                     LFLPLISGGSLLLKGGDTEERLRAALKDNRVTFLKLTPSHLKMLETYADGVDVPNLETL
                     IVGGEEFTTDTAWKTQKLLGESVKIHNEYGPTETTVGCCDYVYSSEKDKGLSVGIGHPI
                     ANMQLYILNEMELCGVGVPGELCIAGDGVAKGYLNQPELTAEKFIDNPYGEGKLYRSGD
                     LARWLPNGEMEYLGRIDEQVKIRGYRIELYEIESVLRNQPGISDVAVVALEVGGDKSIC
                     AYLIPTNQEQQLDMSEIKNDLRDKLPEYMLPGFMMQIDALPLTPNGKLDAKALPEPNAL
                     AGQEYMPPRTKTEKVITDIFEEILGISPVGIEDSFFELGGHSLKATAAINAIEKKTGIR
                     LPVKEIFSSPTPVMLSRKIEAAGEGEYSPIPQAEQREAYPASSTQKRLFILDQMEGNST
                     AYNMASALEVTGNLDVEKIQQAIDRLIKRHESLRTSFVMTEEGAYQVIADEVFYQVEYE
                     ETDSYSDADMEQFVRPFDIGTAPLMRFKVVKERNQNKYILLFDMHHIISDHQTLNLLIE
                     DFSRLYNGEELQPLEIQYKDYSEWMRGRNLESQRNYWKEVFKEEAPVLDLVTDYPRPKT
                     QSYKGAQVSVQLSREQKAGIQNINKQQGTTDYMTLLAVFMIELHKYSRQQDIVVGTPIS
                     GRVHQDTETIAGMFVNTLAMRGYPRGEKTF"
     CDS_motif       112..153
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0001"
                     /evalue="8.30E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg35_1"
                     /protein_end="51"
                     /protein_start="37"
                     /score="18.9"
                     /tool="antismash"
                     /translation="LGVLKSGAAYVPID"
     CDS_motif       325..381
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0002"
                     /evalue="2.30E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg35_1"
                     /protein_end="127"
                     /protein_start="108"
                     /score="29.3"
                     /tool="antismash"
                     /translation="AYLIYTSGTTGKPKGVAVT"
     CDS_motif       889..975
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0003"
                     /evalue="1.60E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg35_1"
                     /protein_end="325"
                     /protein_start="296"
                     /score="55.5"
                     /tool="antismash"
                     /translation="VGVPGELCIAGDGVAKGYLNQPELTAEKF"
     CDS_motif       1054..1119
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0004"
                     /evalue="1.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg35_1"
                     /protein_end="373"
                     /protein_start="351"
                     /score="36.1"
                     /tool="antismash"
                     /translation="YLGRIDEQVKIRGYRIELYEIE"
     aSDomain        1411..1611
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg35_1_PCP.1"
                     /evalue="1.70E-19"
                     /label="ctg35_1_PCP.1"
                     /locus_tag="ctg35_1"
                     /protein_end="537"
                     /protein_start="470"
                     /score="61.7"
                     /tool="antismash"
                     /translation="EKVITDIFEEILGISPVGIEDSFFELGGHSLKATAAINAIEKKTG
                     IRLPVKEIFSSPTPVMLSRKIE"
     aSDomain        1660..2502
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg35_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.80E-94"
                     /label="ctg35_1_Condensation_LCL.1"
                     /locus_tag="ctg35_1"
                     /protein_end="834"
                     /protein_start="553"
                     /score="306.6"
                     /tool="antismash"
                     /translation="EAYPASSTQKRLFILDQMEGNSTAYNMASALEVTGNLDVEKIQQA
                     IDRLIKRHESLRTSFVMTEEGAYQVIADEVFYQVEYEETDSYSDADMEQFVRPFDIGTA
                     PLMRFKVVKERNQNKYILLFDMHHIISDHQTLNLLIEDFSRLYNGEELQPLEIQYKDYS
                     EWMRGRNLESQRNYWKEVFKEEAPVLDLVTDYPRPKTQSYKGAQVSVQLSREQKAGIQN
                     INKQQGTTDYMTLLAVFMIELHKYSRQQDIVVGTPISGRVHQDTETIAGMFVNTLAMRG
                     "
     CDS_motif       1726..1842
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0005"
                     /evalue="4.80E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg35_1"
                     /protein_end="614"
                     /protein_start="575"
                     /score="54.3"
                     /tool="antismash"
                     /translation="TAYNMASALEVTGNLDVEKIQQAIDRLIKRHESLRTSFV"
     CDS_motif       2035..2100
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0006"
                     /evalue="1.50E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg35_1"
                     /protein_end="700"
                     /protein_start="678"
                     /score="20.8"
                     /tool="antismash"
                     /translation="MHHIISDHQTLNLLIEDFSRLY"
     CDS_motif       2131..2160
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0007"
                     /evalue="3.90E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg35_1"
                     /protein_end="720"
                     /protein_start="710"
                     /score="10.0"
                     /tool="antismash"
                     /translation="QYKDYSEWMR"
     CDS_motif       2410..2499
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0008"
                     /evalue="5.50E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg35_1"
                     /protein_end="833"
                     /protein_start="803"
                     /score="44.5"
                     /tool="antismash"
                     /translation="DIVVGTPISGRVHQDTETIAGMFVNTLAMR"
ORIGIN
        1 gtcaaccgca aggccaatgc attggcatgg gaactgattt cgttaggtgt tcagcccaat
       61 gatcgagtgg ccatcatgac taccctggaa gcggaaacga tcattggcat tttgggcgtg
      121 ctaaagagtg gagccgccta tgtcccgatt gatccagcaa caccgaagga acgaatagag
      181 catatcttaa acgatgcagc acccaaggtc attttaacaa gagagaagac tatggaaacg
      241 gaagtcccat tcatctcgat gaatcttgaa gatctgggtg agaaggagac aaatccagcg
      301 tgtgctgttg aaaaaagtga catagcctat ttgatttaca catcaggaac gacaggaaag
      361 cccaaaggcg tggcggttac acgaggtaac ttggatcatt acttgtcgta tgcagatcaa
      421 gaataccaga aggaagcttg tacgacggta ttaatgacaa gcttaagttt cgacctctcc
      481 gtaacgtcct tgttcttacc gctgattagt ggtggatctc ttctattaaa gggaggagat
      541 acggaggaaa ggttacgtgc agctttaaaa gataacaggg taaccttcct gaagcttacc
      601 ccgtcacatt taaaaatgct ggaaacctat gcagacggcg tagatgtgcc gaatttagaa
      661 acgctgattg tcggtggaga ggagttcacc acagatacgg cgtggaaaac gcagaagcta
      721 ttgggtgaaa gcgtcaagat ccataacgaa tatggcccta cagagactac tgtaggatgc
      781 tgtgactatg tctattccag cgaaaaagat aagggtttaa gtgtaggaat cggacatccc
      841 attgccaata tgcagctcta tatactgaat gagatggagt tatgtggtgt aggcgttcct
      901 ggtgagctat gcatcgcagg agacggagta gccaaaggct atctaaacca gcctgaatta
      961 acagcggaga agtttatcga caatccatat ggcgaaggga agttataccg ctctggagat
     1021 ttggcgagat ggctgcctaa cggagagatg gaatacctgg gaagaataga tgaacaggtt
     1081 aaaatccgag gatatcggat cgagttgtac gagatcgaga gcgttctaag gaatcagccg
     1141 ggtatatctg atgtagccgt tgttgcattg gaagtaggcg gtgacaagag tatatgtgcc
     1201 tacctgatcc cgacaaatca agagcagcaa ctggatatgt ctgaaatcaa aaatgatttg
     1261 agagacaaac tgcctgagta tatgttacct ggctttatga tgcagattga tgccttgcca
     1321 ctgactccaa atgggaagct ggatgcaaaa gcactgccag aaccaaatgc attagcagga
     1381 caggaatata tgccaccaag aactaaaaca gagaaagtca ttacggacat atttgaagaa
     1441 atcttaggaa tatctccagt cggcatagag gatagtttct ttgaactggg aggacattcg
     1501 ttaaaagcga cggcagccat taatgccatc gagaagaaga cagggattcg tttgccagta
     1561 aaagagatat ttagttcacc aactcctgtc atgttgtcga gaaagattga ggccgcggga
     1621 gaaggcgaat atagtccaat accacaagca gaacagagag aagcttatcc agcatcctct
     1681 acacagaaac gattgtttat tctggatcag atggaaggta acagtacagc atataacatg
     1741 gcgtcagcgc tagaagtaac gggtaacctt gatgtagaaa aaatacaaca agccatagat
     1801 cgtctgatta agcgtcatga gtcgctgcga acaagttttg taatgaccga agaaggagca
     1861 tatcaagtca ttgcagacga ggtattctac caagtggaat atgaagagac cgacagctac
     1921 agtgacgctg acatggaaca atttgtacgc ccgtttgaca tcggaacagc accgctcatg
     1981 cgttttaaag tagtgaaaga aagaaatcag aacaaatata ttttactatt tgatatgcac
     2041 catattattt ccgatcatca gacgctcaat ctattaatcg aagatttctc acgattgtat
     2101 aacggtgaag aattacaacc acttgaaatc caatacaagg attatagtga atggatgcgt
     2161 ggcagaaacc tggagagtca gagaaactat tggaaagaag tattcaaaga agaggcaccg
     2221 gttttggatt tggtgacgga ctatccacgt ccgaaaaccc aaagctacaa aggagcccaa
     2281 gtgtctgttc agcttagccg agagcagaaa gctggcattc aaaatataaa taaacaacag
     2341 ggaacgacag attacatgac cttactggct gtatttatga tagaactgca taaatacagc
     2401 aggcaacaag atatcgtggt aggaacaccc atctcaggcc gagtgcatca ggacaccgag
     2461 acaatagccg gcatgtttgt caatacgctg gcaatgagag ggtatccaag gggcgagaaa
     2521 acgttc
//
