LOCUS       c00022_gnlPro..        23237 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JBIJPFBC_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 04:12:20
            Original ID  :: gnl|Prokka|JBIJPFBC_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 55487
            Orig. end    :: 78724
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23237
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[65487:68724]"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13237
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
     cand_cluster    1..23237
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /kind="single"
                     /product="fatty_acids-unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23237
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="fatty_acids-unassigned"
                     /region_number="1"
                     /rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /tool="gutsmash"
     CDS             343..1188
                     /locus_tag="ctg22_73"
                     /transl_table=11
                     /translation="MTSKKERLDVLLVERGLAETREKAKRAIMAGIVYSNENRLDKPGE
                     KIDRDLPLTVKGNPLRYVSRGGLKLEKALKEFPVSVKDKIMIDIGSSTGGFTDCALQNG
                     AKQSYAVDVGYNQLAWKLRQDERVVVMERTNFRYATPADFTKGMPEFATIDVSFISLRL
                     ILPVLRTLLVPGSDCMALVKPQFEAGRESVGKKGIVRDPKVHADVLKRMISFSAAEGYI
                     CKGLSFSPITGGDGNIEFLLHLHWPGEGQEGQELPEEEIMRVVEEAHKTLKEKKADVPE
                     "
     CDS             1286..1735
                     /locus_tag="ctg22_74"
                     /transl_table=11
                     /translation="MNKGQRHIKIREIITSNEIETQDELVDMLKQDGYKVTQATVSRDI
                     KELHLVKVPTNNGSYKYSLPADQRFNPLSKLKRALMDAFVKIDSASHMIVLKTMPGNAQ
                     AIGALMDNLDWDEIMGTICGDDTILIICRTPGDTDGVKNRLLELL"
     CDS             1772..3502
                     /locus_tag="ctg22_75"
                     /transl_table=11
                     /translation="LLAELSIKNFAIIEELTVSFERGLTVLTGETGAGKSIIIDAISLL
                     VGGRGSSEFVRYGEAKAELEGLFLLESGHPVLGVCAEQGIDVSDEMIVMRRDISTSGKS
                     VCRVNGKLVTIASLREIGRLLLDIHGQHDNQLLMEDENHLQLLDKFAGAEVESALKTYQ
                     EGYQRYMKLLKKLKQLSESEQEMAHRLDLIQFQLEEIESAKLELNEDKQLQEERQEISN
                     FEKIYESLQNAYNALRSEQGGLDWVGMASAQLEDISDINEPLKKLSESVSNSYYLLEDA
                     TFQMRNMLDELEFDPERLNYIETRLNEIKQLKRKYGATVEDILEYASKIEEEIDQIENR
                     DSHLQSLKKELDSVGKDVAVEAANVSQIRKTWAKKLADEIHRELKSLYMEKSTFDTEFK
                     VRTASRNEEAPLVNGQPVQLTEQGIDLVKFLISTNTGEPLKSLSKVASGGELSRVMLAI
                     KSIFSSQQDVTSIIFDEVDTGVSGRVAQAIAEKIHKVSIGSQVLCITHLPQVAAMADTH
                     LYIAKELKDGRTTTRVKPLSKQEKVAEIGRMIAGVEVTDLTKRHAKELLKQADQVKTTG
                     "
     CDS             3677..4957
                     /locus_tag="ctg22_76"
                     /transl_table=11
                     /translation="MPDNIRKAVGLILLVSLLSVGLCKPLKEYLLIPTQMRVFETQTQA
                     IETSLSVNAQTSESSEAFTVKKDPHEIKVTGKKSGKSELVYDLAGFPIKKTKVHVLPDL
                     KVIPGGQSIGVKLHSVGVLVVGFHQINTSEGKKSPGETAGIEAGDIIIEMNGQKIEKMN
                     DVAPFIQKAGKTGESLDLLIKRDKQKIKTKLIPEKDEGEGKYRIGLYIRDSAAGIGTMT
                     FYEPKTKKYGALGHVISDMDTKKPIVVENGEIVKSTVTSIEKGTGGNPGEKLARFSSER
                     KTIGDINRNSPFGIFGTLHQPIQNNISDQALPVAFSTEVKKGPAEILTVIDDDKVEKFD
                     IEIVSTTQQKFPATKGMVLKITDPRLLKETGGIVQGMSGSPIIQNGKVIGAVTHVFVND
                     PTSGYGVHIEWMLSEAGIDIYGKEKAS"
     CDS             5233..6036
                     /locus_tag="ctg22_77"
                     /transl_table=11
                     /translation="VEKIKVCVADDNRELVSLLSEYIEGQEDMEVIGVAYNGQECLSLF
                     KEKDPDVLVLDIIMPHLDGLAVLERLRESDLKKQPNVIMLTAFGQEDVTKKAVDLGASY
                     FILKPFDMENLVGHIRQVSGNASSVTHRAPSSQSSIIRSSQPEPKKKNLDASITSIIHE
                     IGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEV
                     AWSRGNIDSISSLFGYTVSMTKAKPTNSEFIAMVADKLRLEHKAS"
     CDS             6322..6435
                     /locus_tag="ctg22_78"
                     /transl_table=11
                     /translation="MKKKKARKREGLFLDFLFEVGGELFLLLFRCVHKLFI"
     CDS             complement(6477..7625)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Oxidored_FMN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_79"
                     /sec_met_domain="Oxidored_FMN (E-value: 6.9e-123, bitscore:
                     403.0, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRIQTKEDDQMNPKYKPLFEPFTFKSGVTIDNRIAVAPMTHYASN
                     EDGTISEAELDYIIPRSKEMGMVITACANVTPDGKAFPGQPAIHDDSNIPGLKKLAQAI
                     QAQGAKAVVQIHHGGIECPSELVPQQDVVGPSDVFDNGKQIARALKEEEVENIVKAFGE
                     ATRRAIEAGFDGVEIHGANGYLIQQFYSPKTNQRTDRWGGSDEKRLAFPLAIVDEVKKA
                     ASEHAKGAFLVGYRLSPEEPETPGLTMTETYTLVDALGDKELDYLHISLMDVNSKARRG
                     ADPTRTRMDLLNERVGNKVPLIAVGSIHSADDALAVIENGIPLVAMGREILVDPNWTLK
                     VKEGREKQIETVIKGTDKEKYHLPEPLWQAIVNTPGWVPYKD"
     CDS             8128..8424
                     /locus_tag="ctg22_80"
                     /transl_table=11
                     /translation="VKQTVLLLFTALFLSGCSVASADDSVPRFTEEGKYIGSADPHTIA
                     VSLNGEETMIQVPKDKRDECESLPDQTHVLVKYTKKDNGTLQLEDIQLRKNSS"
     CDS             8444..9064
                     /locus_tag="ctg22_81"
                     /transl_table=11
                     /translation="LRMLWRSLALCGLALTLAPCAQAAEPIEGKTVYIDAGHGGEDSGA
                     VGNGLFEKDINLAVSEHVTDKLKEEGANPVASRSDDHFLTLEERVAKASANQADLFVSI
                     HVNSGVASASGTETYFQSDYEGENSRRLASDIQSELVSSLQTRDRGVKESDFYVITYSQ
                     MPSVLAELGFITNSSDADKLGSEEYQQKAADAIVNGIDSYYDQ"
     CDS             9143..9874
                     /locus_tag="ctg22_82"
                     /transl_table=11
                     /translation="MTKIFAHRGASGQFPENTMLAFEKGIEAGADGIELDVQLTKDGRI
                     VVIHDERLNRTTSLKGFVKDTAYDEVKTANAAAGHDQAYSEIKVPLLEDVLSWAVKKDF
                     LINIELKNSVIRYEGMEEKVLEAVKRFNVEERVILSTFNHDSLALCARLAPHIERAVLT
                     SDVLYQADRYIASIPASGYHPKLNSPGVTDEGLKKMRNSSIKVRPYTVNRPEDMKRLIE
                     AGADGMFTDFPEKASALLKNE"
     CDS             10001..11182
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_83"
                     /sec_met_domain="Thiolase_N (E-value: 1.6e-102, bitscore:
                     335.1, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 5.2e-51, bitscore:
                     164.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKTVIVSAARTPFGKFGGVLKEVKAAELGGIVMKEALQRAGVSG
                     DDVEGNVMGMVVQAGSGQIPSRQAARLSGMPWSVPSETLNKVCASGLRAVTLCDQMIRA
                     QDANILVAGGMESMSNIPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGNT
                     AAMEYAISRREQDEWALRSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIRR
                     DTSLDQLAKLSPIYASDGSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFST
                     TGMPAHELAAAPGFAINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVNV
                     NGGAIALGHPIGASGARILMTLVYELKRRGGGLGVAAICSGAAQGDAVLVQVH"
     CDS             11207..12070
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_84"
                     /sec_met_domain="HCDH (E-value: 2.9e-39, bitscore: 126.5,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 4.8e-68, bitscore: 221.4,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKQIMVAGAGQMGSGIAQTAADADFYVRMYDVNPEAAEAGLKR
                     LKKQLARDAEKGKRTETEVKSVISRISISQTLEEAEHADIVIEAIAENMAAKTEMFKTL
                     DRMCPPHTILASNTSSLPITEIAAVTSRPQRVIGMHFMNPVPVMKLVEVIRGLATSEET
                     ALDVMALAKKMGKTAVEVNDFPGFVSNRVLLPMINEAIYCVYEGVAKPEAIDEVMKLGM
                     NHPMGPLALADFIGLDTCLSIMEVLHSGLGDSKYRPCPLLRKYVKAGWLGKKSGRGFYD
                     YEERTS"
     CDS             12098..13237
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_85"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.6e-57, bitscore:
                     186.8, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.9e-29, bitscore:
                     94.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.6e-40, bitscore:
                     131.1, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LHVTQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGE
                     HGLMGIPVPEQYGGAGADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQ
                     KMKYIPKLASGDHLGAFALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADI
                     YITFALTAPDQGRHGISAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPKANL
                     LGKEGDGFHIAMANLNVGRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQAISF
                     KLADMATRAEAARHLVYHAADLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYG
                     YMKDYPVERLLRDAKVTQIYEGTNEIQRLIISKYLLGGT"
     CDS             13271..14389
                     /locus_tag="ctg22_86"
                     /transl_table=11
                     /translation="MEEKQQYSPGLDGVIAAETHISYLDTQSSQILIRGYDLIELSETK
                     SYLELVHLLLEGRLPEESEMETLERKINSAASLPADHLRLLELLPEDTHPMDSLRTGLS
                     ALAGYDRQIDDRSPSANKERAYQLLGKMPALTAASYRIINKKEPILPLHTLSYSANFLY
                     MMTGKLPSSLEEQIFDRSLVLYSEHEMPNSTFAARVIASTHSDLYGALTGAVASLKGNL
                     HGGANEAVMYLLLEAKTTSDFEQLLQTKLKRKEKIMGFGHRVYMKKMDPRALMMKEALQ
                     QLCDKAGDHRLYEMCEAGERLMEKEKGLYPNLDYYAAPVYWMLGIPIPLYTPVFFSART
                     SGLCAHVIEQHANNRLFRPRVSYMGPRYQTKS"
     CDS             14404..15822
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MmgE_PrpD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_87"
                     /sec_met_domain="MmgE_PrpD (E-value: 2.3e-153, bitscore:
                     503.6, seeds: 231, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKTDRVIVEITDYVLEKEITSAEAYTTAGHVLLDTLGCGILALR
                     YPECTKLLGPIVPGTTVPNGSKVPGTSYVLDPVRAAFNIGCMIRWLDYNDTWLAAEWGH
                     PSDNLGGILAAADYVSRVRLSEGKEPLTVRDVLEMMIKAHEIQGVLALENSLNRVGLDH
                     VLFVKVATTAVAAKLLGGGREEIKNALSNAWIDNAALRTYRHSPNTGSRKSWAAGDATS
                     RGVHLALMSLKGEMGYPTALSAPGWGFQDVLFNKKEIKLARPLDAYVMENVLFKVSYPA
                     EFHAQTAAECAVILHPQVKNRIDEIDRVVIRTHESAIRIIDKKGPLHNPADRDHCLQYI
                     TAIGLLFGDITAQHYEAETANDPRIDKLRDKMEVTENKTYTEDYLKPDKRSISNAVQVH
                     FKDGTSTEMVECEFPLGHRFRREEAVPKLLEKFSDNLKTHFPDKQHKHIYERCTSYETL
                     QTMRVNEFVDMFCM"
     CDS             15840..16745
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_88"
                     /sec_met_domain="PEP_mutase (E-value: 9.2e-55, bitscore:
                     178.5, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWIVNKQSSQEELAGRFRKLMSAPDILQIPGAHDGMAALLAKEA
                     GFSAIYLSGAAYTASRGLPDLGIITSAEIAERAKDLVRAADLPLLVDIDTGFGGVLNAA
                     RTAREMLEARVAAVQIEDQQLPKKCGHLNGKQLVPIKEMAQKIKVIKQTAPSLIVVART
                     DARAQEGLDAAIKRSEAYIGAGADAIFPEALQAENEFRQFAERIPVPLLANMTEFGKTP
                     YYRADEFEDMGFHMVIYPVTSLRAAAKACERMFGLMKEHGSQKEGLHDMQTRKELYDTI
                     SYYDYEALDKTIAKTVLPDE"
     CDS             17176..19254
                     /locus_tag="ctg22_89"
                     /transl_table=11
                     /translation="MQKVLIVGAGKRGTALLHILIKTAIIDIIAVVDKDPEAPGLKEAE
                     QYGIAVSSDWKPYIQQKPDIVIHTTGDQAVFDELLQRKHEDTIVMPGKMAYIVFQLMEE
                     KQHLIQMLKEQTYKYDRIFNSTHDGMIFIDINEEIILFNHMAEKMVGKKREEVIGRPIK
                     EVIPSTKMPRILKTRVPEYNQKQLLGDHLQIVTTRLPIIDEGGRLLGALCVFKDITDAV
                     ELAEEVTNLKQVRTMLEAIIQSSDEAISVVDENGIGLLINKAYTKMTGLSEKEVIGKPA
                     NTDISEGESMHLKVLETRRPVRGVRMKVGPNEKEVIVNVAPVIVDGILKGSVGVIHDVS
                     EIKMLTAELNRARQIIRTLEAKYTFDDIIGKSEQMLVALEQAKLGAKTPATILLRGESG
                     TGKELFAHAIHNESDRKYNKFIRVNCAALSENLLESELFGYEDGAFSGAKRGGKKGLFE
                     EANNGSIFLDEIGELTQNMQAKLLRVLQEKEIVRVGGTKAIPVNVRVIAATNVNIEKAM
                     ADGTFREDLYYRINRYPISIPPLRQRLEDIEALSVRLIQKINRDYGRNVKGLSQQALRA
                     LSAYHWPGNVRELENVLGRAMIFLNPHMEWIEKDHLPVFELEQKENDTDQGTGFDFPDI
                     EGEKLSVAVEKFEAHLIQQTLEKHHFNRTKTAKALGVSIRNLYYKMDKYGLANEGMQ"
     CDS             19379..20278
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTA_PTB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_90"
                     /sec_met_domain="PTA_PTB (E-value: 3.4e-50, bitscore:
                     163.9, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKDLIGKASIHKNKTIAVAHAEDEEVIRAVKLAAEHLSARFLL
                     TGDSKKLNELTSSMQGHQVEIVHANTPEESAKLAVRAVHHKTADVLMKGNVPTSVLLKA
                     VLNRQEGLRSASVLSHVAVFDIPDFDRLMFVTDSAMNIAPSLEELRQILQNAVHVAHAV
                     GNNMPKAAALAAVETVNPKMEATVNAAALAQMYKRGQIKGCIVDGPLALDNAVSQIAAA
                     QKKISGDVAGIADILLVPTIEAGNILYKSLIYFAKASVAAVITGAKAPIALTSRADSAE
                     NKLYSIALAICASEEYTH"
     CDS             20290..21384
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ELFV_dehydrog"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ELFV_dehydrog_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_91"
                     /sec_met_domain="ELFV_dehydrog (E-value: 1.1e-11, bitscore:
                     37.7, seeds: 97, tool: rule-based-clusters)"
                     /sec_met_domain="ELFV_dehydrog_N (E-value: 1.2e-30,
                     bitscore: 98.9, seeds: 410, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELFKYMEKYDYEQLVFCQDEQSGLKAIIAIHDTTLGPALGGTRM
                     WTYENEEAAIEDALRLARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEEMFRAFGRYIQ
                     GLNGRYITAEDVGTTVEDMDIIHDETDYVTGISPAFGSSGNPSPVTAYGVYRGMKAAAK
                     AAFGTDSLEGKTIAVQGVGNVAYNLCRHLHEEGANLIVTDINKQSVQRAVEDFGARAVD
                     PDDIYSQDCDIYAPCALGATINDDTIKQLKAKVIAGAANNQLKETRHGDQIHEMGIVYA
                     PDYVINAGGVINVADELYGYNAERALKKVEGIYGNIERVLEISQRDGIPAYLAADRLAE
                     ERIERMRRSRSQFLQNGHSVLSRR"
     CDS             21409..22494
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Butyrate_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_92"
                     /sec_met_domain="Butyrate_kinase (E-value: 8.1e-155,
                     bitscore: 507.5, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLHDEKRILTINPGSTSTKIGVFHNERSIFEKTLRHNIEELQRFD
                     RIIDQYEFRKNHILETLHEQGINISKFDAVCARGGLLRPIEGGTYVVNDEMIEDLKSGY
                     AGQHASNLGGIIAREIADGLNIPSYIVDPVVVDEMSVLAKVSGMPEIERKSIFHALNQK
                     AVARKAAASLGKRYENMKMIITHMGGGITIGVHDRGRVVDVNNGLHGEGPFSPERAGTV
                     PAGDLVDLCFSGEYTKEEIMKKLVGTGGLLGYLGTNDAVKVEQMIQGGDEKARFIYDAM
                     AYQVAKEIGAASAALKGEVEAIVLTGGLAYGKSFVSAIRSYIDWISDVLVYPGENELQS
                     LAQGALRVLQGEEQSKQYRIE"
ORIGIN
        1 agccgaagag ctgcagaaag aaggcctttc cgtgcgcgtt gtgaatgcgc gttttattaa
       61 gccgattgat gaaaagatga tgaagagtat cctaaaagaa ggcttgccaa ttttaacaat
      121 tgaagaagcg gtcttagaag gcggtttcgg aagctcgatt ttagaattcg ctcatgatca
      181 aggtgaatat catactccga ttgacagaat gggtatacct gatcggttta ttgaacacgg
      241 aagcgtaaca gcgcttcttg aggaaattgg actgacaaaa cagcaggtgg caaatcgtat
      301 tagattactg atgccgccaa agacacacaa aggaattgga tcatgacgtc aaagaaagaa
      361 cgattagatg tattattagt ggaaagaggg ctggcggaaa cgcgtgaaaa agccaaaaga
      421 gccattatgg cggggatcgt ctattcaaac gaaaaccgct tggacaagcc tggagaaaaa
      481 attgaccgcg accttccgtt aaccgtcaaa ggaaacccgt tgaggtatgt gagcaggggc
      541 ggcttaaagc tcgaaaaagc gttgaaggaa tttcccgtct ctgtcaaaga taaaattatg
      601 attgatattg gctcctccac cggcggtttt acggactgcg ctttgcaaaa tggagctaaa
      661 cagtcatacg ctgtggatgt aggctataat cagcttgcat ggaagcttag acaggatgaa
      721 cgggtcgtcg tgatggaacg gacgaacttt cgttatgcaa caccggcaga ctttacaaag
      781 ggcatgccgg agtttgccac aattgatgtg tcctttattt cactgcggct catcctgcct
      841 gtcctaagga ctttactcgt accgggcagc gactgcatgg ctctagttaa gcctcagttt
      901 gaagcgggac gggaatccgt cggcaaaaaa gggattgtca gagatcctaa agtgcatgca
      961 gatgtgctca agcgaatgat cagtttttct gccgctgaag gctatatctg taaaggcttg
     1021 tcattttctc caatcacggg aggagacgga aatattgagt ttctccttca tttgcattgg
     1081 ccgggagagg gacaggaagg ccaggagctg ccggaagaag agatcatgcg cgttgtagaa
     1141 gaagcacata agacgttaaa agaaaaaaaa gcagatgtac cggaataata gggcgctatt
     1201 attccttttt tctgcattca tgtacaatgt gcagagaatc atataacata aaagaacaga
     1261 taagcttgga aatagaggtg cttacatgaa caaaggccag aggcatatta aaatcagaga
     1321 gatcattaca agcaatgaaa tcgaaacgca ggatgaattg gtcgacatgc taaagcagga
     1381 tggatacaaa gtaacgcaag ccacggtatc acgggatatt aaagaacttc accttgtaaa
     1441 agtgcctaca aataatggtt cttacaaata cagtcttccg gcggaccagc gtttcaatcc
     1501 gctgtctaag ctaaagcggg ccttgatgga cgcatttgtg aaaatagact ctgcaagcca
     1561 tatgatcgta ctgaaaacga tgccgggcaa tgctcaggca atcggggcgc tgatggacaa
     1621 tttggactgg gatgaaatta tggggaccat ttgcggagat gacacgattt taattatttg
     1681 ccggactcct ggagatacag acggtgtaaa aaacaggctc cttgaactgc tgtaacagaa
     1741 attctaacaa agataagagg tgtaatgctg tttgttagct gaactatcga ttaaaaactt
     1801 tgccattatt gaggaactga cggtttcttt tgaacgcggg cttacggttt taacaggaga
     1861 aaccggagcc ggcaaatcca ttatcataga tgccatttct cttttagtcg gaggccgcgg
     1921 atcatctgaa tttgttagat atggggaagc aaaagctgaa cttgaagggc tgtttctgtt
     1981 ggagagcggc catcctgttt taggcgtatg cgctgagcag ggaatcgacg tttcagacga
     2041 aatgatcgtc atgagaaggg atatcagcac gagcgggaaa agcgtttgcc gtgtcaatgg
     2101 caagcttgtc acgattgctt cgctaagaga gatcggcagg cttttattag atattcacgg
     2161 acagcacgat aaccagctgt taatggaaga cgaaaatcat ctccagcttt tggacaagtt
     2221 tgccggggcc gaagtggaaa gcgcgctcaa aacgtatcag gaaggatacc agcggtatat
     2281 gaagctgctc aaaaagctta agcagctttc tgaaagcgaa caggaaatgg cccatcgtct
     2341 tgatcttatt caatttcagc tcgaagaaat cgaatcggca aagcttgagc ttaacgaaga
     2401 taaacagctc caagaagagc gccaggaaat ttcaaacttt gagaagatat atgaatcgct
     2461 gcaaaatgca tataacgcgc ttcgcagtga gcagggcgga ttggactggg tcggaatggc
     2521 ttcagcgcag cttgaagata tctctgatat taacgaaccg ctgaaaaaac tgtctgaaag
     2581 tgtttcgaac tcctactatt tgcttgagga tgccacattt cagatgagaa atatgctgga
     2641 tgagcttgaa tttgatccgg aacgcttgaa ctatattgag acacgactta atgaaatcaa
     2701 acagctgaaa cgaaaatacg gtgccactgt tgaagacatt ttggaatatg cttctaaaat
     2761 tgaagaagag attgaccaaa ttgaaaacag ggacagccac cttcaaagct tgaaaaagga
     2821 gcttgactcc gtcggcaaag atgtcgcagt ggaagcggca aatgtgtcac aaatccgaaa
     2881 aacatgggcg aaaaagctgg ctgatgagat tcatcgggaa ttaaaaagcc tgtacatgga
     2941 aaaatcaact ttcgatacgg aatttaaggt cagaacagcg tcacgcaatg aagaggcgcc
     3001 gcttgtaaac ggccagcccg ttcagctgac tgaacaaggg attgacctgg tgaagttttt
     3061 aatttcaacc aatacaggcg agccgctgaa atccctttcg aaagtcgctt caggtggaga
     3121 gctgtcacgg gtgatgcttg ccataaaaag cattttctcc tcacaacagg atgtgacatc
     3181 gatcattttt gacgaggttg ataccggtgt aagcggcagg gtcgcacagg caatcgctga
     3241 gaagatccat aaggtgtcaa taggttcaca agtgctgtgc attacacacc tgcctcaggt
     3301 ggctgccatg gccgatacgc atctttatat tgcgaaggag ttaaaagacg gcagaacgac
     3361 gacacgtgtc aagccgctct ctaagcagga aaaggtagcg gaaatcgggc gcatgattgc
     3421 aggtgtcgaa gtaaccgact taacgaaacg ccatgcgaaa gaacttttaa aacaagcgga
     3481 tcaagtcaaa acaactgggt aagctgcgcg agaagcgcag cttatttttt tcgtgcgcat
     3541 ccattcgttc atcagtatat ccaatgtttt tcttcatatg acagttataa ataagccgtc
     3601 agaaggcaaa attaaatgat gtagcaacaa gtcataaaga aggtgtggga taggagcgag
     3661 gagagtgaag tagtgaatgc ccgataacat cagaaaagca gtaggtttaa ttctccttgt
     3721 ttcgttatta agtgtaggtt tatgcaaacc gctaaaagaa tatttactga ttccaacgca
     3781 aatgagagta tttgaaaccc aaacacaagc gattgaaacg agtttatcgg taaacgctca
     3841 gacatcagaa tcctcagaag cgtttacagt aaagaaagat ccgcatgaaa tcaaggtgac
     3901 gggcaaaaaa tcaggtaagt cagaattagt atacgatctt gccggatttc caattaaaaa
     3961 aacaaaagtg cacgttcttc ctgatttaaa agttatacct ggcggacaat caatcggtgt
     4021 aaaacttcat tccgtcggtg ttcttgtcgt cggatttcat caaatcaata caagtgaagg
     4081 caaaaaatct ccgggagaaa cggccggaat tgaagcgggc gacatcatta ttgagatgaa
     4141 tggacagaaa attgaaaaaa tgaatgatgt agccccattt attcaaaagg ctgggaaaac
     4201 tggtgaatct ttagatttac tgatcaaacg tgataaacag aaaatcaaaa cgaagctgat
     4261 cccagaaaag gatgaaggag aaggcaaata cagaatcggg ttatatatca gagattctgc
     4321 tgccggcatc ggcactatga ccttttatga accgaaaaca aaaaaatacg gagcacttgg
     4381 ccacgtgatt tccgatatgg acacaaagaa accaattgta gtggagaatg gagaaatcgt
     4441 taaatccact gtaacatcaa ttgaaaaagg gacaggcggt aatccgggag aaaaactggc
     4501 gcgattttcc tcagaacgca aaacgatcgg ggatattaac aggaacagcc cgtttgggat
     4561 tttcggcaca ctgcatcagc cgattcaaaa caacatatca gatcaagcat tgccggttgc
     4621 gttttctacc gaagtcaaaa aagggccggc tgaaatttta accgttattg atgatgacaa
     4681 agtagaaaaa ttcgatattg aaatcgtcag cacaacgcag caaaaattcc ctgcgacaaa
     4741 aggaatggtg ttgaaaatta ccgatccaag gctgttgaaa gaaacaggag gcatcgtaca
     4801 ggggatgagc ggaagcccga ttattcaaaa tggaaaagtg atcggtgctg tcacccatgt
     4861 atttgtaaat gacccgacaa gcggctacgg tgttcatatt gaatggatgc tgtcagaagc
     4921 aggaatcgat atttacggaa aagaaaaagc aagctgactg ccggagtttc cggcagtttt
     4981 tttattttga tccctcttca cttctcagaa tacatacggt aaaatataca aaagaagatt
     5041 tttcgacaaa ttcacgtttc cttgtttgtc aaatttcatt tttagtcgaa aaacagagaa
     5101 aaacatagaa taacaaagat atgccactaa tattggtgat tatgattttt ttagagggta
     5161 tatagcggtt ttgtcgaatg taaacatgta gcaagggtga atcctgttaa ctacatttgg
     5221 ggaggaagaa acgtggagaa aattaaagtt tgtgttgctg atgataatcg agagctggta
     5281 agcctgttaa gtgaatatat agaaggacag gaagacatgg aagtgatcgg cgttgcttat
     5341 aacggacagg aatgcctgtc gctgtttaaa gaaaaagatc ccgatgtgct cgtattagat
     5401 attattatgc cgcatttaga cggacttgcg gttttagaga ggctgaggga atcagatctg
     5461 aaaaaacagc cgaatgtcat tatgctgaca gcctttggac aggaagatgt cacgaaaaag
     5521 gccgtcgatt taggcgcgtc ctactttatt ctcaaaccgt ttgatatgga aaaccttgtc
     5581 ggccatatcc gccaggtcag cggaaatgcc agcagtgtga cgcatcgtgc gccatcatcg
     5641 caaagcagta ttatacgcag cagccagcct gaaccaaaga agaaaaatct cgacgcgagc
     5701 atcacaagca ttatccatga aatcggcgtc ccagcccata ttaaaggcta tctctatctg
     5761 cgcgaagcaa tctcaatggt atacaatgac atcgaattgc tcggcagcat tacaaaagtc
     5821 ctctatccgg acatcgccaa aaaatttaac acaaccgcaa gccgtgtaga aagagcgatc
     5881 cgccatgcaa ttgaagtggc atggagcaga ggaaacattg attccatttc ctcgttgttt
     5941 ggttatactg tcagcatgac aaaagctaaa ccgacaaatt cggaattcat tgcaatggtt
     6001 gcggataagc tgagattaga acataaggct tcttaaacat gagcttatta agtggtcatt
     6061 aaatcaaacg tcttttattt attagtttgc gctgataaat aggaggcgtt ttgttttggg
     6121 gacatttgtt agtatgggag aagaatatta agtatccgca tatagtaaag gataggtttg
     6181 aattacctgc actcttggtc cattcataca tcttatagga tcacgaagca ggatcgactc
     6241 tagatgtgtc cgttataaaa tgaaaccttt ctcctgcaaa atcgtaagta aggcgtattc
     6301 atgtaaaaag gagacgtacg aatgaaaaag aaaaaagcaa gaaagcgtga ggggcttttc
     6361 ctggattttc ttttcgaagt tggtggggag ctctttcttt tgctgtttag atgtgtacac
     6421 aaactattta tataaaggga aaaaagactg ccgaacgttt cggcagtctt tgcacattaa
     6481 tctttataag gcacccagcc tggcgtgttc acaattgctt gccaaagcgg ttcaggcaaa
     6541 tgatattttt ctttatctgt gcctttgatc actgtttcga tttgcttttc acggccttct
     6601 tttactttta gcgtccagtt agggtcaact agaatttcgc gtcccatagc gactagcgga
     6661 ataccgtttt cgatgacggc aagcgcgtca tcagcggaat ggatggaacc gacggcgatc
     6721 agaggcactt tgtttccgac acgttcattc aataagtcca tgcgtgtgcg agtcggatct
     6781 gcaccgcggc gcgcttttga gttcacgtcc atcagtgaga tatgaagata atccaattct
     6841 ttatccccta aagcatcaac aagcgtataa gtttcagtca ttgtcaatcc cggtgtctca
     6901 ggttcttccg gagacaggcg gtatccgact aagaacgcac ccttcgcatg ttctgaagcg
     6961 gcttttttca cttcatcgac aatagcgagc gggaaggcta atcgtttttc atcgcttcct
     7021 ccccagcgat ccgtgcgctg gttggttttc ggagaataaa actgctgaat taagtagccg
     7081 tttgcaccgt gaatttcgac accgtcaaag cccgcttcaa tggcacgtct tgtcgcttct
     7141 ccaaacgcct tcacaatgtt ttccacttct tcttctttta atgcgcgagc aatttgtttg
     7201 ccgttatcaa acacgtcact tggccccaca acatcttgtt gaggaacaag ctcagacggg
     7261 cattcaatac cgccgtgatg aatttgtaca acagctttag cgccttgtgc ctgaatggct
     7321 tgtgctaact tttttaaacc tggaatgttg gaatcgtcat ggatggccgg ctgcccgggg
     7381 aatgcttttc cgtccggtgt aacatttgcg caggctgtaa tcaccattcc catctctttt
     7441 gaacggggga tgatgtagtc gagctccgct tcagatattg taccgtcttc attagaagcg
     7501 taatgagtca ttggtgctac tgcgatccgg ttgtcgattg taacgccgct tttaaacgta
     7561 aatggttcaa acagaggctt atacttagga ttcatttgat catcttcttt cgtttggatt
     7621 cgcacatatt ctagcctata tgtaaaaatt aatgcaattg atctgcttta ccgactgaat
     7681 atcttgagtg cagagtgatg ttttcgccgc tctttttcgg ggcctttgta gccgccgctg
     7741 atttggtggc cgatggagca tgtgatgaca gctgccgcca gcagcagaac gaattttttc
     7801 atggctttaa cttctttcaa taaagtaaat atcctttaaa aggttacgct tggctgaccc
     7861 acccgtcaaa cgatttgctc accctattct caaatttttt aaaatgaata aaaagttgct
     7921 tctttccgct aattttttct aattggcgcc tcaattagag ccatcctcat agacaaatct
     7981 gctcgttatc tttctaacaa caggaaatga tcgggtcgta tagccctttt gaaaatcatg
     8041 gaacttgctc gcctgcattc gcgttgtctt tacaaattcg ccattctggt caaagataaa
     8101 agccaaacat caggaagagg tggtcatgtg aaacaaacgg ttcttttgct gtttactgcg
     8161 ctctttcttt cggggtgcag tgttgcaagt gcggatgact cagtgccaag gtttaccgaa
     8221 gagggaaaat acattggctc ggctgatcct catacgattg cggtttctct taatggagaa
     8281 gaaaccatga tacaagttcc gaaggataaa cgtgatgaat gtgaatcact gccagatcag
     8341 acacatgtcc tggtgaaata tacaaagaag gataatggaa ctttacagct ggaagatatt
     8401 cagctgcgaa agaactcgtc ataaaaagac cggagggagt aagttgagaa tgttatggag
     8461 gagcttggcg ctgtgcggat tggctttgac gctcgcgcct tgtgcacagg cagcagagcc
     8521 gatagaagga aaaacagtgt atattgatgc cggacacggc ggtgaagaca gtggagcggt
     8581 cggaaacggg ctctttgaaa aggatattaa tttggctgtc tcagagcatg tgacagacaa
     8641 actaaaagag gagggagcca atcctgttgc atcccggtct gacgatcatt ttctgacctt
     8701 ggaggaaaga gtggctaagg caagtgccaa tcaggctgac ctttttgtca gcattcatgt
     8761 gaattcaggg gttgcttcag cttcaggaac agaaacgtat tttcaatctg attatgaagg
     8821 ggagaacagc cggcgtctcg catccgatat tcagtcagag ctcgtttctt ccttacaaac
     8881 gagagacagg ggcgtgaaag aatcagactt ttacgtcatt acatattcac aaatgccaag
     8941 tgtgttggcg gagcttgggt ttatcacgaa cagctctgat gcggacaagc tgggaagtga
     9001 agaataccag caaaaggccg cagatgcgat tgtcaacggc attgattctt attatgatca
     9061 gtagattgat acagccttaa tcctagagtg gagccgacaa aataagtata atggagaaaa
     9121 ctttagggtt tgaggtgaaa cgatgacaaa gatttttgcc caccgggggg cctcaggtca
     9181 atttcccgaa aatacaatgc ttgcatttga aaaaggaatt gaagccggag cggatgggat
     9241 agagcttgat gtacagctga cgaaagacgg acgcattgtt gtgattcatg atgaaagact
     9301 taatcgcacg acatcactta aaggattcgt gaaggataca gcctatgatg aggtaaagac
     9361 tgcgaatgcg gccgctggtc acgatcaagc gtacagcgaa ataaaagtgc cgctgctaga
     9421 agatgtgctc tcgtgggcgg taaaaaagga ttttctcatc aacattgaat taaaaaacag
     9481 cgtgatccgc tatgagggaa tggaagaaaa agtgctggag gcagtgaaac gattcaatgt
     9541 agaggagaga gtcatcctat ccacgtttaa tcatgacagc ttggcgctat gcgcccggct
     9601 tgcgccgcat atcgaacggg cagtattaac ttcagatgtg ctttaccagg cagatcgata
     9661 tatcgcgtct attccggctt ccggctatca cccgaagtta aacagcccag gggtcacaga
     9721 tgaaggtcta aagaaaatga ggaacagttc gattaaggta aggccgtata cagtcaatcg
     9781 tccggaagat atgaagcgtc tcattgaagc gggagcagac ggcatgttta ccgactttcc
     9841 agaaaaggct tcggcattgc tgaaaaatga atagttgtta gaaggaggct gtttgacgca
     9901 gccttctttt ttcattcatt catgcccgtt tcaaagcata cattcataga agacaactag
     9961 aaattgtaag cgctgtctat cttctgaatg aggtgaaacc atgaggaaaa cagtcattgt
    10021 aagtgctgca agaactccat ttggcaaatt cggcggagtt ttgaaagagg tgaaagctgc
    10081 tgagcttggg ggcattgtga tgaaggaggc gctgcaacgg gctggagtct ctggagatga
    10141 tgtagaagga aacgtcatgg gcatggttgt ccaggccggc tcagggcaga taccttcccg
    10201 tcaagctgcc cgtctgtcgg gaatgccttg gagtgtgccg tcagaaacac tgaataaagt
    10261 ctgtgcttcc ggccttcgcg ctgtcacttt atgtgatcaa atgattcggg cgcaggatgc
    10321 gaacatactt gttgcggggg gaatggaaag catgagcaat attccgtatg ccgttcccgc
    10381 tgggcgctgg ggagcacgga tgggggacgg cgagcttagg gacttaatgg tgtatgacgg
    10441 attaacgtgc gcatttgacg aggtgcacat ggctgttcac ggaaatacag ctgccatgga
    10501 atatgcaatc tcacgaagag agcaggacga atgggcgttg agaagtcatg caagggcagc
    10561 taaggctgcc gatgaaggga agtttcagga tgaaattgtt cccgtcaact ggatcggtcg
    10621 aaaaggaaaa ccaaacgttg ttgataaaga tgaagcgatt cgccgtgaca caagtctgga
    10681 tcagctcgcg aaactttctc ctatttatgc aagtgacggt tctatcacag ccggcaatgc
    10741 tcctggagtc aatgacggag ccggcgcgtt cgtgctgatg tctgaggaaa aagctgctga
    10801 gcttggcaaa cggcctctgg ctacaattct tggtttttca actacgggaa tgccagcgca
    10861 cgagctggcg gcagcaccgg gatttgccat taacaagctt ctgaaaaaga acggtttaac
    10921 tgtccaagat attgacttgt ttgaagtaaa tgaagctttt gcttcagttg ttttgacatg
    10981 tgaaaaaatc gtaggtttcg atcttgaaaa agtaaatgta aatggcggtg cgatcgcgct
    11041 cggccacccg atcggcgcga gcggtgcgag aattctcatg acgcttgttt atgaattaaa
    11101 gcgacgggga gggggtctgg gcgttgccgc tatttgtagc ggggcagcac agggagacgc
    11161 cgtcttagtg caggttcatt aaaacatgat gaaaaagggg atttgaatgg aaatcaaaca
    11221 aatcatggta gctggcgcag gtcagatggg aagcggaatt gctcaaacag ctgccgacgc
    11281 ggacttttat gtgcggatgt atgatgtgaa tccagaggcc gctgaggcag gattgaaacg
    11341 gctgaagaaa cagctggccc gcgatgctga gaaaggaaaa aggaccgaga cggaagtgaa
    11401 gagcgtaatc agccgcattt cgatttctca aacgcttgag gaggcagagc atgcggacat
    11461 tgtgattgag gctatcgcag aaaacatggc ggcaaaaact gagatgttta aaacacttga
    11521 tcgcatgtgc ccgcctcata cgattttggc cagcaataca tcttccttgc ctattacaga
    11581 aatcgctgct gtaacaagcc ggcctcaacg ggttattggc atgcatttta tgaatcccgt
    11641 ccctgtaatg aagctggttg aagtgattcg cggcttggct acatcagaag aaacggcctt
    11701 agatgttatg gcattagcga aaaagatggg gaaaacagcg gtagaagtca atgattttcc
    11761 tgggtttgtt tccaaccgtg tgcttcttcc aatgattaat gaagccatct attgcgtgta
    11821 tgagggagtg gcgaagccgg aggcaataga cgaagtgatg aagctgggca tgaatcatcc
    11881 gatgggtccg cttgcattag cggattttat cggactggat acgtgtttat caattatgga
    11941 agtccttcac tcaggccttg gcgattccaa ataccgtcct tgcccgctgc tccgcaagta
    12001 tgtcaaagca ggctggcttg gcaaaaagag cggacgcggt ttttatgact atgaggagag
    12061 gacttcctaa agtctattcc atccgggggt ggccgagttg catgtaaccc aagagcaagt
    12121 catgatgcga aaaatggtgc gtgattttgc acgaaaagaa attgctcccg ctgcggaaat
    12181 catggagaaa acggacgaat ttccctttca gctgatcaaa aaaatgggtg aacacggact
    12241 gatgggaata ccggtgccgg aacaatacgg cggtgccggg gcggacgttg tttcttatat
    12301 tttggcgatt catgagattt ctagaatcag tgcggctgtc ggcgtgatac tctccgttca
    12361 tacctcagtc ggcacgaatc cgattctgta tttcggcaac gaagaacaaa agatgaaata
    12421 tataccaaag ctcgcgtcag gagaccattt gggcgcattt gcactaacgg agcctcactc
    12481 ggggtcggat gccgggagcc tccgcacaac agcaatcaaa aagaacggca aatatctatt
    12541 aaacggatcg aaaatattca taacgaatgg cggagcagct gatatctata tcacatttgc
    12601 tttaacagct ccagatcaag gcaggcacgg gatttcggct tttattgttg aaaaaaacac
    12661 acccggtttt accgttggaa aaaaagaaag aaagctgggg ctttatggct ccaatactac
    12721 ggaactgatt tttgataatg cagaagtgcc taaagccaat ttgcttggca aagaggggga
    12781 tggctttcac attgccatgg cgaatttaaa tgtcggccgg atcggcattg cggcacaggc
    12841 cctcggaatt gcagaggcag ctcttgagca tgccgttgat tatgcgaagc agcgagtgca
    12901 atttggaagg ccgatcgcag ccaatcaagc catatcattt aagctggctg acatggcgac
    12961 tagagctgag gcggcaagac atcttgtcta ccacgctgca gaccttcata accgcggcct
    13021 aaactgtgga aaagaagcgt ctatggctaa acaatttgct tccgatgcag ccgtaaaggc
    13081 ggcgttagac gccgttcaaa tttatggagg atatggctat atgaaggatt atccggttga
    13141 gcgcttgctt cgcgatgcaa aggtgacgca aatctatgaa gggacgaacg agattcaaag
    13201 actgattatt tctaagtatt tgcttggcgg aacctgatgg acaaaaaacg cataaacgga
    13261 ggttgaggat atggaggaga aacagcaata ttctccaggg ttggacggtg tgattgcggc
    13321 agaaactcat atttcttatc ttgacacgca gtccagccag attttgataa gaggctatga
    13381 tttaatagaa ctttctgaaa caaaaagcta tctggagctt gtccatttat tgctggaggg
    13441 caggctgcca gaagaaagtg aaatggagac gctggaacgt aaaataaaca gtgccgcaag
    13501 cctgcctgct gatcatctcc gtctgcttga gctgctccct gaggacactc acccaatgga
    13561 tagtctgcgt accggcctgt cggcacttgc tggctatgat cggcaaattg atgatcggtc
    13621 tccctccgca aacaaagaac gcgcctatca gcttcttggg aaaatgcctg ccctcactgc
    13681 tgccagctac aggatcatta ataagaaaga accgattctt ccgcttcata ccttatccta
    13741 cagtgcgaat tttctataca tgatgacagg gaaattgccg tcttcattgg aagaacagat
    13801 ttttgaccgg tcgctcgtcc tgtacagtga gcatgagatg ccgaattcaa cctttgcggc
    13861 cagggtcatt gcatctacac attcagatct ttatggggct ttgactgggg ctgtcgcttc
    13921 cctgaaaggg aatcttcacg gaggagcaaa cgaagctgtg atgtatttgc ttttggaggc
    13981 aaaaacgaca tctgattttg agcagcttct gcaaacaaaa ctgaaaagaa aagaaaaaat
    14041 catgggcttc ggccaccggg tgtatatgaa aaaaatggac ccaagagcac tcatgatgaa
    14101 agaggcgctg cagcaattat gcgataaagc cggtgaccat cgtttatatg agatgtgtga
    14161 agcgggtgag cggctgatgg agaaggaaaa agggctttac ccgaatttgg attactatgc
    14221 tgccccggtg tattggatgc tcggcatacc gattccttta tatacgccgg tctttttcag
    14281 cgcgagaacg tccggtttat gcgcccatgt gatcgaacag catgccaata atcggctctt
    14341 ccgtccccgt gtcagttaca tgggcccgcg atatcaaaca aaatcatgaa aggagctggt
    14401 agaatgccga aaacggatcg tgtaatcgta gaaatcacag actatgtgct tgaaaaagag
    14461 attactagtg ccgaagcgta tacaacagcg gggcatgtat tgctggatac cctgggctgc
    14521 gggatcttgg cgctacgata tccggaatgc acaaagctgc ttggcccgat tgttccagga
    14581 acgactgtgc cgaatggaag caaagtgccg ggaacgtcat atgttctcga tcctgtgagg
    14641 gcagcgttta atatcggctg catgattcgc tggctcgatt acaacgatac gtggctggcg
    14701 gcggagtggg ggcatccatc cgataacttg ggaggaatcc ttgccgctgc tgattatgta
    14761 tcaagagtga ggctgtctga aggaaaagag ccgttaacag tacgcgacgt acttgagatg
    14821 atgatcaaag cacacgagat tcaaggtgtg ctggcgttag aaaacagctt aaatcgagtt
    14881 ggccttgacc atgtgctgtt tgtcaaagtt gcgacaaccg ctgttgcggc aaagcttttg
    14941 ggcggcggaa gagaagaaat caaaaatgcg ctttcgaatg catggattga caatgcagca
    15001 ttgaggacat accgccattc accgaataca ggctcgcgta aatcatgggc ggcaggagat
    15061 gcaacgagca gaggtgttca tttggcgctg atgtcgttaa aaggggaaat gggttatccg
    15121 acagccctga gtgcaccggg ttgggggttc caagacgttt tattcaataa gaaagagatc
    15181 aagcttgccc gtccgcttga cgcttatgtc atggaaaatg tgttatttaa agtgtcttat
    15241 cctgcggaat ttcacgccca gacagcggcg gagtgcgccg tcattcttca cccgcaggta
    15301 aagaaccgga ttgacgagat agaccgagtt gttatcagaa cgcatgaatc cgctatccgt
    15361 atcattgata aaaaaggccc gctccacaat ccggcagacc gtgatcactg tctccaatac
    15421 attacagcaa tcggtttgct ttttggtgat atcaccgcac agcattatga agctgaaaca
    15481 gcgaatgatc cgagaataga taaacttcgt gataaaatgg aagtgactga aaataaaaca
    15541 tataccgagg attatttgaa gcctgataaa cgctccatct caaatgccgt tcaggttcat
    15601 tttaaagacg gaacgagcac ggaaatggtg gaatgtgagt ttcccctcgg ccatcgtttt
    15661 cgaagagagg aagcagtgcc taaactgctg gaaaagtttt ctgacaatct caaaacccat
    15721 tttcctgata aacagcacaa acacatttat gagcgctgta ccagctatga gacattacaa
    15781 acgatgcgcg taaatgaatt cgtagacatg ttctgcatgt aaaaggggga ttttgtttca
    15841 tgtcgtggat cgttaataag caatcgtcac aagaggagct tgccgggcgt ttccgcaagc
    15901 tgatgtcagc accggacatt cttcaaattc ccggcgccca tgacgggatg gccgctttgc
    15961 ttgcgaaaga agccggtttt tctgctattt atttgtccgg tgctgcctat acagccagca
    16021 gggggctgcc tgatttaggg atcatcacat cggcagagat agctgaacgt gccaaagatc
    16081 ttgtgcgtgc agctgatctg cctttgcttg tggatatcga tacgggattt ggcggtgtct
    16141 taaatgccgc ccgaacagcc cgggagatgc ttgaagccag ggtagcagcc gttcaaatag
    16201 aagaccagca gctcccaaaa aaatgcggac atttaaatgg caaacagcta gttccgataa
    16261 aggaaatggc gcaaaaaata aaagtcatta aacaaacggc accctccctt attgttgttg
    16321 cccgtactga tgccagggcg caggaagggc ttgatgccgc aataaaacgt tcagaggctt
    16381 acattggggc gggagcggac gcaattttcc cggaagcgct acaggcggag aatgaattcc
    16441 gccagtttgc tgagcgtatc cccgttccgc tccttgcgaa tatgactgaa tttgggaaaa
    16501 cgccgtatta tcgtgccgat gaattcgaag atatggggtt tcacatggtg atatatcctg
    16561 tcacctcgct tcgagcggcg gcaaaagctt gtgagcggat gtttggtttg atgaaggagc
    16621 acggctcaca aaaagaagga cttcatgata tgcagacacg aaaagaactg tacgatacga
    16681 tttcttatta tgactatgaa gcgttagaca aaacgattgc caagaccgtt ttgcctgacg
    16741 aatagtgcaa caaaaaaagc cggagcattc tccggctttt tttcagctat cgttttctga
    16801 atcgcgggct gacttgattg cgttttctgt ctctgtataa aatgaacccg gccagcacat
    16861 agaggccgat cgcaaaaaag atgaatcctg acaacccttg gagccaaaga gctgaaaatg
    16921 gcttgattgt atggccgaaa agtgtatctc tcatcagttt aatgcctaaa gcagaaatag
    16981 ccccggggat gactaatatt aaaagcgcaa gaagtcggct catcttcaga aaaccccttt
    17041 atcttttcat ttcctttatt gtccagcgga aaaaatattt tgtcaagaga agaaaacgtg
    17101 gtaacatagg gttgtgcaaa ttattgcaac ggaataaata ggtgtgcaaa ttttttcatg
    17161 caaaggggta tcgggatgca aaaggtactg atagtaggtg ccggcaaaag gggaacggcg
    17221 ttattacata ttctgattaa aacagccatc atagatatca ttgccgtagt tgacaaagac
    17281 cccgaagcgc cgggattgaa agaagcagaa cagtatggga ttgccgtatc atctgattgg
    17341 aaaccttaca tacaacaaaa accggatatc gtcattcata ccaccggcga tcaagccgtg
    17401 tttgacgagc tccttcaaag aaagcatgaa gataccattg tcatgccagg aaaaatggca
    17461 tacatcgttt ttcagctgat ggaagaaaag cagcacctga ttcaaatgct aaaagagcaa
    17521 acctataaat atgacagaat ttttaattcc acccatgatg gaatgatttt tattgatatc
    17581 aatgaagaaa tcattctctt taaccatatg gccgaaaaaa tggtcggaaa aaaacgtgag
    17641 gaagtcattg ggcgcccaat aaaagaagtg attccgagca ctaagatgcc gcggatttta
    17701 aaaacaagag tgcctgaata caaccagaag cagctgttag gcgatcattt gcaaattgtg
    17761 accacaagac tgccgattat tgatgaaggc ggacgtctgc tcggggctct ttgtgtgttt
    17821 aaagatatca ctgatgcggt cgagctggca gaggaagtga ccaacttaaa gcaggtccgt
    17881 acgatgctgg aggcaattat tcaatcctcc gatgaggcga tttctgtcgt tgatgaaaac
    17941 ggcatcggcc tgctaatcaa taaagcgtat acgaaaatga cggggctttc tgaaaaagaa
    18001 gtcatcggca agcctgcaaa cactgatatt tccgaaggcg aaagcatgca tttaaaggtg
    18061 cttgaaacaa gacgtcctgt ccgcggtgtc agaatgaagg tcggcccgaa tgaaaaagag
    18121 gtcatcgtta atgtagcacc ggtgattgtg gacgggattt tgaaaggcag cgtcggcgtg
    18181 attcacgatg tttccgaaat taaaatgctg acagcggagc ttaatcgcgc cagacaaatt
    18241 attcgcacgc ttgaagcgaa atacacgttt gacgacatta tcggcaaaag cgagcaaatg
    18301 ctggttgcgc ttgagcaggc gaagctcggt gcgaaaacac cggcaaccat cttgctgcgc
    18361 ggggaatcag gaacaggaaa agaactgttc gcccatgcca tccataacga aagtgaccgg
    18421 aaatacaata aatttattcg cgtgaattgt gcagcccttt ctgaaaacct gctcgaatca
    18481 gaattgttcg gctatgagga tggtgcgttt tcaggagcga agcgcggcgg taaaaagggt
    18541 ttatttgagg aagcaaataa cggcagtatt ttcttagatg aaatcggtga gctgacacaa
    18601 aatatgcagg ccaaattgct acgcgtcctt caagaaaagg aaatcgtcag agtgggcggc
    18661 acgaaagcga tccctgtcaa cgtcagagtg atcgcggcga caaatgtaaa tattgaaaag
    18721 gcgatggcgg acggaacatt ccgggaagac ctgtattacc ggatcaatcg ctatccgatc
    18781 tccatcccgc ctttgcggca gcggttggag gacattgaag cattgagcgt cagacttatc
    18841 caaaagatca accgggatta cggcaggaat gtaaaagggc tctcacagca agccttgcgc
    18901 gccttatctg cctaccattg gcctgggaat gtccgggagc ttgaaaatgt ccttggacga
    18961 gccatgattt ttctgaatcc gcatatggaa tggattgaaa aagatcactt gcctgtattc
    19021 gaacttgagc aaaaagaaaa tgacacagat cagggaacag gttttgattt tccggatatt
    19081 gaaggcgaaa agctgtctgt cgcagtagaa aaatttgaag cgcatttgat ccagcaaacg
    19141 cttgaaaagc atcattttaa ccggacaaaa acagcaaaag ctctcggtgt cagcattcgg
    19201 aacttatatt acaaaatgga taaatatggc cttgcaaatg aaggcatgca ataatttgca
    19261 gaataaacgc aaacatctgc acgaatgttt cggtatacct ggtatgacag cacccttaag
    19321 agctggcatg gaacttgcat aataaaaggc ggagtcgaaa caagaaaggt ggtaacagat
    19381 gaagctgaaa gatttaatcg gcaaagcgtc gatacacaaa aataagacca ttgcggttgc
    19441 tcatgctgag gatgaggaag tgatccgggc tgtaaagctg gcagccgagc acctatccgc
    19501 ccgtttcttg ttaacgggcg acagcaaaaa actgaacgag ctgacatcat ccatgcaagg
    19561 gcatcaagtg gaaatcgtcc atgccaatac tcctgaggaa tcggcgaaat tagcggttcg
    19621 tgctgtgcat cataaaacag cggacgtttt aatgaaaggc aatgtgccga cttctgtttt
    19681 gcttaaagcg gtattgaaca gacaggaggg gcttcggtca gcaagtgtcc tttcccacgt
    19741 ggctgtcttc gatataccgg attttgaccg gctgatgttt gtgacagatt cggcaatgaa
    19801 tattgctcct tcgctggaag agctccggca gattttgcaa aatgccgttc atgtggccca
    19861 tgcagtaggg aacaatatgc caaaagcagc tgcccttgca gcggtcgaaa cggtgaatcc
    19921 aaaaatggaa gcaaccgtga atgcagctgc tctagctcaa atgtacaaaa ggggccagat
    19981 caaaggctgc attgttgatg gaccgcttgc tttggataac gcagtttcac aaattgccgc
    20041 ggcccagaaa aaaatttcgg gagacgtagc gggcatcgca gatatccttc tcgtcccaac
    20101 aattgaggcc ggcaatattt tatataaatc actgatttat tttgccaagg ccagcgtggc
    20161 ggctgtcata acaggagcca aagcaccgat tgccttaaca agcagagcgg actctgctga
    20221 aaataaactg tattccattg cgctggcaat atgcgcatct gaagaataca cacattagga
    20281 ggaacgaaca tggaactttt taaatatatg gagaaatacg attacgaaca attggtattc
    20341 tgccaggatg aacaatctgg cttaaaagcg attatcgcca ttcatgatac aacgcttggt
    20401 ccggcgcttg gcggaacgag aatgtggaca tatgaaaatg aagaagcggc aattgaagat
    20461 gcgctcagat tggcaagagg catgacctat aagaacgcgg cggcaggctt aaaccttggc
    20521 ggcggaaaaa cagtcattat cggcgatccg cgcaaagaca aaaatgagga aatgttccgc
    20581 gcgtttggcc gctatattca agggctgaat ggcagataca tcacggctga agatgtgggt
    20641 acaacggtcg aggatatgga tatcattcat gatgagacag actatgtcac agggatttct
    20701 cctgctttcg gctcttctgg aaatccgtcc ccagtcacag cgtacggggt gtacagagga
    20761 atgaaggcag cagctaaagc tgctttcgga accgactctc ttgaaggaaa aaccattgct
    20821 gtacagggtg ttgggaacgt agcctataac ctttgccgcc acctgcatga agaaggagca
    20881 aacttaatcg ttacggatat caacaaacaa tctgtacagc gtgcagttga agattttggc
    20941 gcccgtgctg tagatcctga tgacatttat tcacaagact gcgatattta tgcgccgtgt
    21001 gcccttggtg caactattaa cgacgacacc attaaacagc tgaaggcgaa agtgatcgca
    21061 ggtgcggcta acaaccaatt aaaagagaca cgccatggtg atcaaattca cgaaatgggc
    21121 atcgtttatg caccggatta cgtgattaac gcgggcggtg ttatcaacgt ggcagatgag
    21181 ctttacggct ataatgcaga acgtgcattg aaaaaagttg aaggcattta cggcaatatc
    21241 gagcgtgtac tagagatttc tcagcgtgac ggcattcctg catatttagc ggctgaccgc
    21301 ttggcagagg aacggattga acgcatgcgc cgctcaagaa gccagttttt gcaaaacggc
    21361 cacagtgtat taagcagacg ttaagaaatt gatctggagg ttatgaaagt gctacatgac
    21421 gaaaaacgca ttctcacaat taatccaggc tcaacttcaa cgaaaatcgg tgtttttcat
    21481 aacgaaagaa gcatttttga aaaaacattg agacacaaca tagaagagct gcagcgattt
    21541 gaccgaatta ttgatcagta tgaatttcgt aaaaaccata ttctcgaaac gcttcatgaa
    21601 cagggaatca atatctcaaa gtttgatgca gtctgcgcaa gaggcggcct tctccggcca
    21661 attgaaggcg ggacctacgt ggtgaatgat gagatgattg aggatttgaa aagcggctac
    21721 gccggtcagc atgcttctaa tctcggcggc attatcgcgc gggaaatcgc tgatggcctg
    21781 aatatccctt cgtatatcgt cgaccctgtt gtcgtagacg aaatgtcagt gcttgcgaaa
    21841 gtttcaggca tgcctgaaat tgaacggaaa agcattttcc atgcgttaaa ccaaaaagct
    21901 gtcgctcgta aagcggcagc ctctcttggc aaacgatatg agaacatgaa aatgattatt
    21961 acccatatgg gcggaggtat tacaattggc gtccatgacc gcgggcgagt ggtagatgtc
    22021 aataacggcc tgcacggcga ggggccattc agtcctgaac gagcaggaac agtgcctgcg
    22081 ggagatcttg ttgatctatg tttttcaggg gaatatacaa aagaagaaat catgaaaaag
    22141 cttgttggca ccggcggact tttaggctat ctcggtacaa atgatgcagt aaaagtagaa
    22201 cagatgattc aagggggcga tgaaaaagcc cgcttcattt atgatgccat ggcatatcag
    22261 gtagcaaagg aaatcggggc agccagcgcg gcgttaaaag gcgaagttga agcgattgtg
    22321 ctgacgggag gccttgcgta cggcaaaagc tttgtttctg ctatcagatc atacatagat
    22381 tggatttcag acgttttagt ctatccgggt gaaaatgaac tgcagtctct tgcccaaggg
    22441 gcgctcagag tattgcaggg cgaagagcaa tccaaacaat atcgtattga atagacagac
    22501 aggagtgagt caccatggca actgagtatg acgtagtcat tctgggcggc ggtaccggcg
    22561 gttatgttgc ggccatcaga gccgctcagc tcggcttaaa aacagccgtt gtggaaaagg
    22621 aaaaactcgg aggaacatgt ctgcataaag gctgtatccc gagtaaagcg ttgcttagaa
    22681 gcgcagaggt ataccggaca gctcgtgaag ccgatcaatt cggggtggaa acggctggcg
    22741 tgtccctcaa ctttgaaaaa gtgcagcagc gtaagcaagc cgttgttgat aagcttgcag
    22801 cgggtgtaaa tcatttaatg aaaaaaggaa aaattgacgt gtacaccgga tatggacgta
    22861 tccttggacc gtcaatcttc tctccgctgc cgggaacaat ttctgttgag cggggaaatg
    22921 gcgaagaaaa tgacatgctg atcccgaaac aagtgatcat tgcaacagga tcaagaccga
    22981 gaatgcttcc gggtcttgaa gcggacggta agtctgtact gacttcagat gaggcgctcc
    23041 aaatggagga gctgccacaa tcaatcatca ttgtcggcgg aggggttatc ggtatcgaat
    23101 gggcgtctat gcttcatgat tttggtgtga aggtaacggt tattgaatac gcggatcgca
    23161 tattgccgac tgaagatcta gagatttcaa aagaaatgga aagtcttctt aagaaaaaag
    23221 gcatccagtt cataaca
//
