LOCUS       c00043_gnlPro..        15316 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JBIJPFBC_43.
ACCESSION   c00043_gnlPro..
VERSION     c00043_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 04:12:20
            Original ID  :: gnl|Prokka|JBIJPFBC_43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15316
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..87
                     /locus_tag="ctg43_1"
                     /transl_table=11
                     /translation="KSLFLGIYNFSIMELFEMSINYIDTSII"
     protocluster    1..15316
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3268:5316]"
                     /cutoff="10000"
                     /detection_rule="(Flavoprotein and Phea_decarb and not
                     ubi_syn)"
                     /neighbourhood="10000"
                     /product="hydroxybenzoate2phenol"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3269..5316
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Flavoprotein and Phea_decarb and not
                     ubi_syn)"
                     /neighbourhood="10000"
                     /product="hydroxybenzoate2phenol"
                     /protocluster_number="1"
     cand_cluster    1..15316
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Flavoprotein and Phea_decarb and not
                     ubi_syn)"
                     /kind="single"
                     /product="hydroxybenzoate2phenol"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15316
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="hydroxybenzoate2phenol"
                     /region_number="1"
                     /rules="(Flavoprotein and Phea_decarb and not ubi_syn)"
                     /tool="gutsmash"
     CDS             135..1613
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 62.3; E-value: 1.3e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg43_2"
                     /sec_met_domain="MFS_1 (E-value: 5.1e-20, bitscore: 62.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASIDNESIIKSVPQKGFFGHPRGLFTLFFTEFWERFSYYGMRAI
                     LLYYLYTETVNGGLGFDKGTAVAIMSIYGSLVYMSTIIGGWLADRVFGTANTVFYGGIF
                     IMFGHIALAYPGSAIAFYISMVLIIVGTGLLKPNVSSVVGDLYTKEDPRRDSGFSIFYM
                     GINLGGLLAPLIVGTLGQKYNYHLGFGAAAVGMLLGLIVFALTRKKNLGLAGSNVPNPL
                     SKKSAIGTGIGVIIVAIAVIISVQTGVLTINRFIDLVSILGILIPVIYFIIMFTSKKAD
                     STEKSRLAAYIPLFIGAVMFWAIQEQGATILAVYADERIRLSLGGFELQSSWFQSLNPL
                     FVVIFAPIFAWLWMKLGKRQPSTPVKFSIGIILAGLSFIIMVFPAMQGKEALVSPLWLV
                     LSFLLVVLGELCLSPVGLSVTTKLAPAAFSAQTMSMWFLTNAAAQAINAQVAGLFDKIP
                     ETMYFGTIGLISIVLGGILLLLSPMIKRAMKGVL"
     CDS             complement(1653..2420)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_3"
                     /sec_met_domain="Abhydrolase_1 (E-value: 3e-15, bitscore:
                     47.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIGSAVYYPRLFSSDIKQKYQWVFIDHRGFAKPKRELRAEDSRLD
                     AVLADIERMRTFLQLEDVTILGHSGHAFMALEYARTYPKQVRKVALFNTAPDNSEERQR
                     KSESFFMETASLERKKRFEKDIANLQQDIDKDPERRFVHMCIRAEAKSFYQERPHAAAL
                     WDGVFTNMPIIDELWGNTFARIDLIQRLADVRMPVYIGLGRYDYLVAPVALWDAVDCLY
                     PHVDKVIFERSGHQPMLEEPEAFDQSFRKWLDQ"
     CDS             complement(2564..3028)
                     /locus_tag="ctg43_4"
                     /transl_table=11
                     /translation="LIRVNCMSDRLFELLDGSCLNEKQHEAFVLQTVSEDGWPHAAMIS
                     AGEIIALSRTDIRIALWKNTMTSANILRTGKAQFTAWWKGAAYYVKLECAPLPPLKDAE
                     YERDRFSCCIVSVKEDVAKYADLTSGVRIQLHSAEEVLSRWEKTLEDLKR"
     CDS             complement(3025..3252)
                     /locus_tag="ctg43_5"
                     /transl_table=11
                     /translation="MHTCPRCDSKKGEVMSKSPVEGAWEVYQCQTCFFTWRSCEPESIT
                     NPEKYNPAFKIDPKETETAIEVPAVPERKA"
     CDS             complement(3269..4690)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydroxybenzoate2phenol: Phea_decarb"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_6"
                     /sec_met_domain="Phea_decarb (E-value: 1.4e-247, bitscore:
                     811.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAYQDFREFLAALEKEGQLLTVNEEVKPEPDLGAAARAASNLGDK
                     SPALLFNNIYGYHNARIAMNVIGSWPNHAMMLGMPKDTPVKEQFFEFAKRYDQFPMPVK
                     REETAPFHENEITEDINLFDILPLFRINQGDGGYYLDKACVISRDLEDPDNFGKQNVGI
                     YRMQVKGKDRLGIQPVPQHDIAIHLRQAEERGINLPVTIALGCEPVITTAASTPLLYDQ
                     SEYEMAGAIQGEPYRIVKSKLSDLDVPWGAEVVLEGEIIAGEREYEGPFGEFTGHYSGG
                     RSMPIIKIKRVYHRNNPIFEHLYLGMPWTECDYMIGINTCVPLYQQLKEAYPNEIVAVN
                     AMYTHGLIAIVSTKTRYGGFAKAVGMRALTTPHGLGYCKMVIVVDEDVDPFNLPQVMWA
                     LSTKMHPKHDAVIIPDLSVLPLDPGSNPSGITHKMILDATTPVAPETRGHYSQPLDSPL
                     TTKEWEQKLMDLMNK"
     CDS             complement(4693..5316)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydroxybenzoate2phenol: Flavoprotein"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_7"
                     /sec_met_domain="Flavoprotein (E-value: 5.4e-30, bitscore:
                     94.9, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEMKAEFKRKGGGKVKLVVGMTGATGAIFGVRLLQWLKAAGVET
                     HLVVSPWANVTIKHETGYTLQEVEQLATYTYSHKDQAAAISSGSFDTDGMIVAPCSMKS
                     LASIRTGMADNLLTRAADVMLKERKKLVLLTRETPLNQIHLENMLALTKMGTIILPPMP
                     AFYNQPSSLEEMVDHIVFRTLDQFGIRLPEAKRWNGIEKQKGGA"
     CDS             5397..6269
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     72.5; E-value: 6.9e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg43_8"
                     /sec_met_domain="LysR_substrate (E-value: 1.1e-32,
                     bitscore: 103.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.7e-23, bitscore: 72.5,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LDIRQLRYFITIAQEQKITSAAKKLHMAQPPLSRQLKQLEDELGV
                     VLFDRNKKKQMTLTYEGAVFLKRAKEILHRFEDAVIEVQELKEEVAGTLAVGSTIYCAA
                     LMLEKVTQIKERYPHLTFNIWENEPATLLELLESRQIDAAVTTTLIKSDTVQFKQLDDI
                     PCVLVLSDEAGYPCGDTIKMEDIPSFPLILLRPVNGKGVYDQVMNEFHRLNLEPRIVCE
                     CHDSATLLSLVSSGFGASILPVTMIPVHMRNHVHTVHIENNPFIMTPAVMWRTDSYLPK
                     PAQQFLDLF"
     CDS             6385..7191
                     /locus_tag="ctg43_9"
                     /transl_table=11
                     /translation="MKKALLALFMVVSIAALAACGAGNDNQSKDNAKDGDLWASIKKKG
                     VLTVGTEGTYEPFTYHDKDTDKLTGYDVEVITEVAKRLGLKVDFKETQWDSMFAGLNSK
                     RFDVVANQVGKTDREDKYDFSDKYTTSRAVVVTKKDNNDIKSEKDVKGKTSAQSLTSNY
                     NKLATNAGAKVEGVEGMAQALQMIQQGRVDMTYNDKLAVLNYLKTSGNKNVKIAFETGD
                     PQSTYFTFRKGSGEVVDQVNKALKEMKEDGTLSKISKKWFGEDVSK"
     CDS             7427..7882
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 74; E-value: 4.3e-23)"
                     /gene_kind="transport"
                     /locus_tag="ctg43_10"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.7e-23, bitscore:
                     74.0, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LFIIFYLFPAFNVTLDPFPSAVIAFSLNVGAYASEIIRASILSVP
                     KGQWEAGYTIGMTHQKTLFRVILPQAFRVSIPPLSNTFISLIKDTSLASQILVAELFRK
                     AQEIGARNLDQILVIYIEAAFIYWIICFLLSLVQHVIERRLDRYVAK"
     CDS             7896..8639
                     /locus_tag="ctg43_11"
                     /transl_table=11
                     /translation="MLTVKGLNKSFGENEILKKIDMKIEKGKVIAILGPSGSGKTTLLR
                     CLNALEIPNRGELAFDDFSIDFSKKVKQADILKLRRKSGMVFQAYHLFPHRTALENVME
                     GPVQVQKRNKEEVRKEAIQLLDKVGLKDKMDLYPFQLSGGQQQRVGIARALAIQPELML
                     FDEPTSALDPELVGEVLKVIKDLANEGWTMVVVTHEIKFAQEVADEVIFIDGGVIVEQG
                     QPEQIFSAPKEERTQRFLNRILNPL"
     CDS             9124..9366
                     /locus_tag="ctg43_12"
                     /transl_table=11
                     /translation="VVHHYWSAHRRIHVIVYESLAENWCPPEYGAHWCIYRFFQFHSAC
                     PLDLHRLDHRLLSRRGADWLRRRCLCISRPWRGAA"
     CDS             9374..9610
                     /locus_tag="ctg43_13"
                     /transl_table=11
                     /translation="MMLITEKTGWNVQWVRNGMELTILFAAWGMGGPIGFGTILTAILT
                     GLILRFSLPQSIQLLNYAVARRTAAVKASPPVH"
     CDS             9715..10389
                     /locus_tag="ctg43_14"
                     /transl_table=11
                     /translation="MKIYGIYMDRPLSQEENERFMSFISPEKREKCRRFYHKEDAHRTL
                     LGDVLVRSVISRQYQLDKSDIRFSTQEYGKPCIPDLPDAHFNISHSGRWVICAFDSQPI
                     GIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWSMKESFIKQEGKGLSL
                     PLDSFSVRLHQDGQVSIELPDSHSPCYIKTYEVDPGYKMAVCAAHPDFPEDITMVSYEE
                     LL"
     CDS             complement(10384..11676)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_15"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.6e-23, bitscore:
                     74.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSTAYQEGDRLPSIRQLSARYQVSKSTVIRALQELEKRHLIYSV
                     PKSGYYIVKKTGKSKSGQPGPIDFATSAPDPDVFPYLDFQHCINKAIDTYKNDLFIYGT
                     PKGLPSLIRVLRKLLATQQVFADERHIFITSGVQQALSLLCAMPFPNGKEKIAIEQPGY
                     HLMVEQLETLGIPAIGVKRTEEGLDIAEVERLFQTESIKFFYTMPRFHNPLGCSLSERD
                     KQELVRLAEAYDVYLVEDDYLGDLEENKKADPLYAYDLSSHVIYLKSFSKMMFPGLRVG
                     AAVLPEALTDTFYAYKKLNDIDCSMISQAALEIYLKSGMYGRHKEKIRDSYKERSLRLH
                     QAIRTHRQLGSGRFTFSSGQAPCMHTHLVLPQDLPASRVIHRLKKQGVLLEAIDRHYLS
                     DYPKENLLKINISNVKTEDIERGVNLLMSHL"
     CDS             11842..12780
                     /locus_tag="ctg43_16"
                     /transl_table=11
                     /translation="MVKHQQAPAYIAAILYSFIIGLSFLFVKIALQTAEPFDILAHRFT
                     IAFAAATVPILFGWVKLSIRVKDVIAILPLALLYPALFFSFQAFGLVYSSSSEAGIIQA
                     AIPIFTMVFAAYVLKERPTWTQKGFTVLSVAGVMFIFVMKGVDVESASLKGSLLILLSA
                     LSSAMYNTAARKMTQRFKLTELTYIMSAIGFVVFNAIALVRHGAAGTVGTYFLPFREPG
                     FVLAIVYLGVLSSLVTSFLSNYTLSRIEAFKMSAFNHVSTIVTMIAGVVILKESLAWYH
                     LAGAVCIMIGVVGSNINLEKKTKRSGMPAKK"
     CDS             12834..13391
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) YcxB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_17"
                     /sec_met_domain="YcxB (E-value: 2.8e-14, bitscore: 43.4,
                     seeds: 189, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQYASESINLPGEIAFKDVREIFFYQIAKISCFYFLLFCAIFAA
                     VNFINGWPRIVYGSDALNLFMNSMLIIVMSVLFTLLLLLLLYVKFSRAYKKNERMKSKR
                     TYTLNQEGIRICSKKYDLIFNWDEITAVFEYKNIFRVNTSSGQYIAIPKRFFHSKEEMN
                     RFKGIILKNTGTKKLKFKKDQH"
     CDS             13752..13889
                     /locus_tag="ctg43_18"
                     /transl_table=11
                     /translation="MRLSSRMKNKMDSMTLLLPRRSDSQPANNPPIMINAPNAAIIPLT
                     "
     CDS             13886..14179
                     /locus_tag="ctg43_19"
                     /transl_table=11
                     /translation="MRDMRILQYRDEVSINNSHCKSASKHAEVQDMNEAGLLHHVPKPP
                     PIIRFFHRLRLRMWRVLHPKDEERQQNSRHDDSQNGIGALPAGMIRSRSPNG"
     CDS             complement(14244..14609)
                     /locus_tag="ctg43_20"
                     /transl_table=11
                     /translation="MVCIAVYVCFRHRNELIQKFLSIFYAANGRRLPCRQVADFGFCQH
                     FYDHNRHRPVFCRFFYRPFQCQKNYGAWSCLHQRKLFGASLFTECSCVFRHLRCAWRNR
                     LFLRGRRDDPVFHQPLV"
ORIGIN
        1 aaatcactat ttttaggtat ttataatttt tccattatgg aactatttga aatgagtata
       61 aattatattg acacaagtat tatataagaa tatgattttt ataatacact ttttttagaa
      121 agggtttggc tgacatggct tcgattgata acgaaagtat cattaaaagc gtcccgcaaa
      181 aagggttctt tggtcacccg cgaggactat ttacactatt tttcaccgaa ttttgggagc
      241 gtttctctta ctatggaatg agagcaatct tactttacta tttgtataca gagacggtaa
      301 acggagggct cggctttgac aagggcactg cggttgccat tatgtcgatt tacggatcac
      361 tcgtatacat gtccaccatt attggcggat ggctcgctga ccgggtattc ggtaccgcaa
      421 acaccgtttt ttacggcggc atattcatta tgttcggcca cattgcactc gcctatccgg
      481 gcagcgcgat cgcattctat atcagcatgg tgcttattat tgtcggaaca ggcttattaa
      541 aaccaaacgt ttcaagcgtg gttggggatc tttacacgaa agaagacccg cgccgcgact
      601 caggtttcag tattttctac atggggatta acctcggtgg tttacttgcg ccgttaattg
      661 tcggaacact cggacagaag tacaactatc atctcggctt cggagctgcc gcggtcggaa
      721 tgcttctcgg acttatcgtt tttgctttga caagaaagaa aaacctcggg cttgcaggtt
      781 ccaatgtgcc gaatccgctg tctaaaaaat ctgcgattgg caccggaatc ggtgttatca
      841 tcgtggcgat cgcagtgatt atctctgtac aaacaggcgt gctgacgatc aatcgtttta
      901 tcgaccttgt aagtattctc ggtattttga ttcctgtcat ttatttcatc atcatgttta
      961 caagcaaaaa agcggacagc acagaaaaat cccgtcttgc cgcttacatt cctttgttta
     1021 tcggtgctgt catgttctgg gccattcagg aacagggagc gaccattctt gcggtatacg
     1081 ctgatgaacg aataagactt tcattgggcg gattcgaact tcagtcatca tggttccaat
     1141 cattaaatcc attgtttgtc gtcatttttg caccaatatt cgcatggctc tggatgaagc
     1201 ttggcaaacg ccagccgtct acaccagtta aattctcaat cggaattatt ttggccggat
     1261 tgtcatttat cattatggta ttccctgcta tgcaaggaaa agaagcactc gtaagcccgc
     1321 tttggctcgt tctcagcttc ctgcttgtcg tgcttggaga gctgtgcctg tctccagtcg
     1381 gtttatccgt gacaacgaaa ctggcaccag ctgccttctc tgcacagaca atgagtatgt
     1441 ggtttctgac gaacgcagca gcccaagcga tcaatgccca agtagccgga ttgtttgata
     1501 aaattcctga aacaatgtac ttcggcacca tcggtttgat ttctatcgtt cttggcggca
     1561 ttctcctgct gctctcgccg atgatcaaac gcgcgatgaa aggggtctta taatcagaaa
     1621 cagcccgcgg attttgatct gcgggctgtt ttttattgat caagccattt cctgaagctt
     1681 tgatcaaagg cttccggttc ttccagcatc ggctgatggc cgctcctttc aaaaataacc
     1741 ttatccacat ggggatataa acagtcaact gcatcccata gcgcaacggg cgcaaccaaa
     1801 taatcatatc tccctaatcc gatatacacc ggcatacgaa catcagctaa ccgctgaata
     1861 agatcaatcc gggcaaatgt attgccccat aattcatcaa tgatcggcat attcgtgaat
     1921 acgccatccc ataaggcagc tgcatgcggc cgctcttgat aaaagctttt cgcttcagcg
     1981 cgaatacaca tgtgcacaaa gcgcctttca ggatctttgt cgatgtcctg ctgcaaattc
     2041 gcgatgtctt tttcaaagcg tttctttctc tcaaggctgg ctgtttccat gaaaaatgat
     2101 tcgctttttc gctgtctttc ttcactgtta tcaggcgcag tattgaagag cgccaccttc
     2161 cgaacttgtt tgggatatgt cctggcatac tctaaagcca taaaagcgtg cccggaatgt
     2221 cccaggatag taacatcctc aagctgaaga aatgttctca tcctttcgat atcagccaag
     2281 acggcatcaa gcctcgaatc ctccgcacga agctcccgct taggcttagc aaatccccta
     2341 tggtcgataa agacccattg atatttctgt ttgatatctg aggaaaaaag gcgcggatag
     2401 taaaccgcac tcccgatcac aaggatgggt gcgccctcgc cctcaattcg ataagctaaa
     2461 tcaaagccgt ccgagtgaca gatccccgca cgttccattt ctcacgcccc ctttgttttc
     2521 attatataaa aaaagcctga cgcatggcgt caggctatcg atattaccgc tttaaatctt
     2581 ccagggtctt ttcccatctg ctcagcacct cttcagcgct gtgaagctgt atacggacac
     2641 ctgaagtcaa atcagcgtat ttcgcaacgt cctccttcac tgaaacgatg cagcaggaaa
     2701 aacggtctct ttcatattcg gcatctttca aaggcggtaa aggcgcgcat tcaagcttta
     2761 cataataggc cgctcccttc caccacgccg tgaactgtgc ttttcctgtg cgaaggatgt
     2821 tggccgaagt cattgtgttt ttccacagag cgattcggat atcagttcgg ctcagcgcga
     2881 tgatttcacc tgcactgatc atagcggcat gcggccagcc atcctctgat actgtttgca
     2941 gaacgaaggc ctcatgctgc ttctcattca ggcagctccc gtcaagcagc tcaaagagac
     3001 ggtctgacat acagttcacg cggatcaagc ctttcgttcc ggcaccgccg gaacttcaat
     3061 tgctgtttct gtttcctttg gatcaatttt aaacgctgga ttgtattttt cgggatttgt
     3121 aatgctttcc ggttcacagg atctccatgt aaaaaagcat gtttggcact gataaacttc
     3181 ccatgcgcct tctacaggcg atttgctcat gacttctccc ttttttgagt cgcatcgagg
     3241 acatgtatgc atttcgaaca tcctttcctt atttattcat taagtccatt agtttttgtt
     3301 cccattcttt cgttgttagc ggagaatcaa gcggctgtga ataatggcct cttgtttccg
     3361 gcgcaaccgg tgtagtggcg tcgagaatca ttttgtgagt gattcctgat ggattggatc
     3421 ccggatcaag cggcaggaca gataagtccg gaatgatgac cgcatcgtgt ttcggatgca
     3481 ttttggtcga aagcgcccac atgacctgcg gaaggttgaa tggatcgaca tcctcatcaa
     3541 cgacaatgac cattttgcag tagccgagtc cgtgcggcgt tgtgagtgcg cgcatgccga
     3601 ccgctttcgc aaatccgcca tagcgggttt ttgtggaaac aatcgcgatt aaaccgtgtg
     3661 tgtacatggc gttcactgcc acaatttcgt tcggatacgc ttcttttaac tgctgataaa
     3721 gcggcacgca tgtgttaatg ccgatcatgt aatcgcattc tgtccaaggc atgcctaagt
     3781 ataaatgttc aaagatcgga ttgtttctgt gatagacgcg tttaattttg ataatcggca
     3841 tgctgcgtcc gccggaataa tggcctgtga attcaccaaa cggcccttca tattcgcgct
     3901 ctccggcaat aatctcacct tcaagcacca cttcagcacc ccacggaaca tcaagatcag
     3961 acagctttga tttgacgatg cgatatggtt cgccttgaat cgcgcctgcc atttcgtatt
     4021 ctgattgatc atagagaagc ggagtcgatg ccgccgttgt aatgaccggc tcacagccga
     4081 gcgcaatagt gaccggaaga ttgatgccgc gttcttcagc ttggcgcaga tggattgcaa
     4141 tatcgtgctg cgggacaggc tgaatgccaa ggcggtcttt tcctttgacc tgcattctgt
     4201 aaatgccgac attttgtttg ccgaagttgt cagggtcctc tagatcacgg gaaataacac
     4261 acgctttgtc tagatagtag cctccgtctc cttggtttat tctgaaaaga ggcagtatat
     4321 cgaacaaatt gatatcttct gtgatttcat tttcatgaaa tggcgctgtt tcctcacgtt
     4381 tgacaggcat cggaaattgg tcataacgct ttgcgaattc aaaaaactgt tcttttaccg
     4441 gtgtgtcttt cggcatgccc agcatcattg catggtttgg ccaagagccg atgacattca
     4501 tcgcaattcg cgcgttatga tagccgtaaa tgttgttaaa taagagcgcg ggacttttat
     4561 cgccaagatt gctggctgcc cgtgcggcgg cccctaaatc cggttccggc tttacctctt
     4621 cattcactgt aagcagctgt ccttcttttt caagggcagc gagaaattct ctgaaatctt
     4681 gataagccat gatcaagctc ctcctttttg tttttcaatc ccattccagc gtttcgcttc
     4741 aggaagccga atgccgaatt ggtccaacgt tctgaataca atatggtcaa ccatttcctc
     4801 taagctgctc ggctgattat aaaatgccgg catcggagga agaatgatgg tgcccatttt
     4861 cgtaagcgct agcatatttt cgagatgaat ctggttcaaa ggcgtctctc tcgttaagag
     4921 gacgagtttt tttctctcct tgagcatgac atccgccgca cgtgtcagca gattatccgc
     4981 catgccggtg cgaatgcttg cgagagattt catgctgcac ggcgcaacaa tcattccatc
     5041 ggtatcaaac gacccgcttg aaatggctgc cgcctgatcc ttatgtgagt aagtgtatgt
     5101 ggccagttgt tctacttctt gtaaggtata gcctgtttca tgtttgatcg tgacgtttgc
     5161 ccaaggagac acaacgagat gggtttccac tccggcggcc ttcagccact gcagcagcct
     5221 gaccccgaaa atggcccctg ttgcccctgt cattccgaca acgagtttca ctttgccccc
     5281 tcctttacgc ttgaattctg ctttcatttc aatcatactc ctgatatatc catatgaaaa
     5341 atatctatta aatctatatt taatacctaa aaggtatgat aaggaggcgc tttcttttgg
     5401 acattcgcca gcttcgatac ttcattacca ttgcccaaga acagaaaatc acgtccgcag
     5461 ccaaaaagct tcacatggcg caaccgcctt taagcaggca gctcaaacag ctggaggacg
     5521 aacttggtgt tgttctgttt gaccggaaca agaaaaaaca aatgactctt acatatgaag
     5581 gagctgtttt tctaaaaaga gcaaaagaga ttctgcatag gtttgaagat gcagtcattg
     5641 aggtacagga gctgaaggag gaagtagccg gcacacttgc cgtgggatca acgatttatt
     5701 gcgcggcttt gatgcttgaa aaagtaacac agatcaaaga gagatacccc catctcacct
     5761 ttaatatttg ggaaaatgaa cccgcgacac tgttggaact gctggaaagc cggcaaatcg
     5821 atgcggcggt cacgacaaca ctgatcaaaa gtgacacggt acaattcaaa cagcttgatg
     5881 acattccatg tgtgctcgtg ctttcagatg aagccggata tccgtgcgga gacaccatta
     5941 agatggagga cattccttca tttccgctga tcctgctgcg gcctgtcaac ggaaaaggcg
     6001 tctatgatca ggtcatgaat gaatttcatc gtttgaatct ggagccgcgc attgtttgtg
     6061 aatgccacga ctctgcaact ttgctcagcc tcgtgtcatc cggattcggt gcgtctattt
     6121 tgcccgtcac aatgattccc gttcatatga gaaatcacgt tcacaccgtc catatcgaaa
     6181 ataatccctt cattatgaca ccggctgtca tgtggagaac ggacagttat ttgcctaaac
     6241 cggcacagca atttttggat ttattttaaa agaatttgcc ttatgaaaac caattacttg
     6301 actcatacta aaaaaaagtt atcctttaga tttgtaagct atttttttat ttcaataaaa
     6361 tcaaccagaa aagtggggaa taagatgaaa aaagcattat tggctttatt catggtcgta
     6421 agtattgcag ctcttgcagc ttgcggagca ggaaatgaca atcagtcaaa agataatgcc
     6481 aaagatggcg atctttgggc ttcaattaag aaaaaaggtg tgctcacagt cggaacggaa
     6541 ggaacatatg agccgttcac ttaccacgac aaagacactg ataaactgac tggctatgat
     6601 gtcgaagtta tcacagaagt cgcaaaacgc ctcgggctta aagtcgactt taaggaaaca
     6661 cagtgggaca gtatgtttgc cggcctgaat tccaaacggt ttgacgttgt tgccaaccaa
     6721 gtcggaaaaa cagatcgtga agacaaatat gatttctcag ataaatacac aacatcaaga
     6781 gctgttgtcg taacgaaaaa agacaacaac gatattaagt ctgaaaaaga cgtaaaagga
     6841 aaaacgtcag ctcaatcact gacaagcaac tacaacaaat tagctacaaa tgccggcgct
     6901 aaagtagaag gcgttgaagg tatggcgcag gcccttcaaa tgatccagca aggccgtgtc
     6961 gatatgacat acaacgataa gcttgccgta ttgaactact taaaaacatc tggcaataaa
     7021 aacgtgaaaa tcgcgtttga aacaggtgat cctcagtcaa catatttcac gttccgtaaa
     7081 ggaagcggcg aggttgttga tcaagtcaac aaagcattaa aagaaatgaa agaggacggg
     7141 actctttcta aaatatctaa aaaatggttc ggcgaagatg tttctaaata atctgccggc
     7201 attgacgctt ggcacggcga tcccgtggga tctggtgcag cagtcattct ggccgatact
     7261 ttcaggggga atctactata cgattcccct tacgattctt tcctttatat tcggaatgat
     7321 cctggcgctg attacggcgc ttgccagaat gtcgaaagtg agacctttga gatgggtgtt
     7381 cagcgtatac gtatccgcaa tacgcggcac tcctcttctc gttcaattgt tcatcatttt
     7441 ctatctgttc ccggccttta acgtcacatt agatccattt ccaagcgcag ttatcgcctt
     7501 ttctttaaac gtcggcgcct atgcatctga aatcattcgg gcatctattt tatccgtgcc
     7561 gaaagggcaa tgggaagccg gctacacaat tggcatgaca catcaaaaaa cgctgttccg
     7621 cgtcattttg ccgcaggcgt ttcgtgtgtc gatcccgcca ttatccaata cctttatcag
     7681 cctgattaaa gatacatccc tcgcctctca aattctggtc gctgagctgt tcagaaaagc
     7741 ccaggaaatc ggcgcgcgga atcttgatca aattttagtg atctatattg aagcagcctt
     7801 tatttattgg attatctgct tcctgctctc actcgtccag catgtcatcg aacggcgtct
     7861 tgaccgctac gtggccaaat aaggaggttc cgagtatgct taccgttaaa ggattaaaca
     7921 aatcattcgg tgaaaatgaa attttaaaaa agatagatat gaagattgaa aaaggaaaag
     7981 tcatcgccat acttgggcct tcaggttcag ggaaaacgac gctgctccgc tgcctgaacg
     8041 ctctggagat cccgaatcgc ggagagcttg catttgatga tttctccatc gatttctcca
     8101 aaaaggtgaa acaggcggat atcctaaagc ttcgccgaaa atccggaatg gtgtttcagg
     8161 cgtatcacct gttcccgcac cgcacagccc tcgaaaacgt gatggagggc cctgttcagg
     8221 tgcaaaaacg gaacaaagag gaagtcagaa aagaagcgat tcagcttctt gataaagtcg
     8281 gattgaagga caaaatggat ttatatccgt tccagctttc cggcggacag cagcagcgcg
     8341 tcggcatcgc ccgcgcactg gcgattcagc ctgagctcat gctgtttgac gaaccgacct
     8401 cagcgcttga tcccgagctt gtcggagagg tactgaaggt tatcaaggac ttggccaatg
     8461 aaggctggac catggtcgtc gtgacccacg aaatcaagtt cgcgcaggaa gttgcggatg
     8521 aagtcatctt catcgacggc ggcgttatcg tggagcaagg acagccggag caaattttct
     8581 ccgcaccaaa agaagaacgg acacagcggt tcttgaaccg gattttgaac ccgctgtaat
     8641 aagaaaaaca gggcgccagc gccctgtttc agattattga caaaatccta aaacgatttt
     8701 cgttgtttta ggattttgtg attttcagcg tgattgaaaa cctttgaagt ctaggaaggg
     8761 cgagcattgg agcacagcga atgttaaatt cgtgagcacc gaagcacagg cctgacaacg
     8821 aatgcaaggg tttgccaaca cgctgaaaca gggcgcctgc ggcgaccctg tttttttgtt
     8881 gagccccttt cgcctattcc gcccttctgt cagatgtgct acaatgacaa tcgactgatt
     8941 tttacgaaag aagggacctc acgtgaagca agaacttgtt ctgcgctgga cattttattt
     9001 tgccggtttg atcattttgg cttttggtgt atccctgacg atagaaggaa aagcactcgg
     9061 cattagtccg tgggatgcat ttcattacag cctgtttcag cacttcgggc ttaccgtcgg
     9121 ccagtggtcc atcattattg gagcgctcat cgtcggattc acgtcattgt ttacgagagc
     9181 ttggccgaaa attggtgccc tcctgaatat ggtgctcatt ggtgtattta tagatttttt
     9241 caatttcatt ctgcctgccc cctcgaccta cacaggctcg atcatcgtct tctctctagg
     9301 cgtggtgctg attggttacg gcgtcggtgt ttatgtatca gcaggccttg gcgcggggcc
     9361 gcgtgattca ctgatgatgc tgattacaga aaaaaccggc tggaatgtgc aatgggtgcg
     9421 gaacggcatg gaattaacca ttttgtttgc ggcatggggc atgggcggac cgatcggttt
     9481 tggcaccatt ctgaccgcca tcctcaccgg acttattttg cgtttttcat tgccccagtc
     9541 aatccagttg ctgaattatg ctgtggcaag gcggacagcc gctgtgaaag catctccgcc
     9601 tgtacactaa aacaaagccg ccttggcttt gtttttttat tttctcctct atatgagtct
     9661 tgtggaagta tgataggatg gttttgacaa tcttttgcag acggaggatc tagaatgaag
     9721 atttacggaa tttatatgga ccgcccgctt tcacaggaag aaaatgaacg gttcatgtct
     9781 ttcatatcac ctgaaaaacg ggagaaatgc cggagatttt atcataaaga agatgctcac
     9841 cgcaccctgc tgggagatgt gctcgttcgc tcagtcataa gcaggcagta tcagttggac
     9901 aaatccgata tccgctttag cacgcaggaa tacgggaagc cgtgcatccc tgatcttccc
     9961 gacgctcatt tcaatatttc tcactccggc cgctgggtca tttgcgcgtt tgattcacag
    10021 ccgatcggca tagatatcga aaaaacgaaa ccgatcagtc ttgagatcgc caagcgcttc
    10081 ttttcaaaaa cagagtacag cgacctttta gcaaaagaca aggacgagca gacagactat
    10141 ttttatcatc tatggtcaat gaaagaaagc tttatcaaac aggaaggcaa aggtttatcg
    10201 cttccgcttg attccttttc agtgcgcctg catcaggacg gacaagtatc cattgagctt
    10261 ccggacagcc attccccatg ctatatcaaa acgtatgagg tcgatcccgg ctacaaaatg
    10321 gctgtatgcg ccgcacaccc tgatttcccc gaggatatca caatggtctc gtacgaagag
    10381 cttttataga tggctcatca acaggttgac accgcgctca atatcttccg ttttcacatt
    10441 ggaaatattg atttttaata gattttcttt cggataatct gataaataat gacggtctat
    10501 cgcctcaagg agaacccctt gttttttcag cctatgaatc actcttgagg cgggcagatc
    10561 ctgaggaagc accagatggg tgtgcataca gggtgcctgc ccgctggaga acgtaaagcg
    10621 tccgcttccc agctgcctgt gagttcgaat ggcttgatgt agcctcagcg accgctcttt
    10681 ataagaatct ctgattttct ccttatgcct gccgtacata ccgcttttca ggtaaatctc
    10741 caatgctgct tgagaaatca tcgaacagtc gatgtcgttc agttttttgt acgcatagaa
    10801 cgtgtcagtc agcgcttcgg gcaaaacagc cgcccccacg cgaaggccgg ggaacatcat
    10861 tttcgagaag cttttcaaat agatgacatg tgaggacaga tcatatgcgt acagcggatc
    10921 tgccttttta ttttcctcca gatcaccgag gtaatcatcc tcaacgagat agacatcata
    10981 cgcttctgcc agtctcacaa gctcctgttt atcacgctct gacaatgagc agccaagcgg
    11041 gttatggaag cgcggcatcg tataaaaaaa tttaatcgat tctgtttgaa ataaccgctc
    11101 aacctcggct atatcaagcc cttcttccgt tcgtttcacc ccgatggcgg gaatcccaag
    11161 cgtctcaagc tgttcgacca tcaaatggta gcccggctgt tcaatggcga tcttctcttt
    11221 cccatttggg aacggcatgg cacaaagcaa ggataacgcc tgctggacac ctgatgtaat
    11281 gaaaatatgc cgttcatccg caaatacctg ttgagtggcc aagagctttc ggagtacgcg
    11341 gatgagtgat ggaagcccct ttggcgtccc ataaataaac aaatcgtttt tgtatgtatc
    11401 aatcgctttg ttgatacagt gctgaaaatc aagatacgga aacacatctg gatccggcgc
    11461 agatgtggca aagtcgatgg ggccaggctg cccgcttttt gatttccctg tctttttcac
    11521 aatataatag ccgcttttcg gaacagaata gataaggtgg cgcttttcca gctcctgcag
    11581 cgcgcggatc actgtgcttt tgctgacttg gtagcgggcg gacagctgac ggatagatgg
    11641 aagcctgtct ccttcttgat aggcggtgct ttgcatcatc tcctctatcc tcgttactag
    11701 actcatatat ttctccatgc cttctccccc tgttttgtac cggtacagtt cattgttttt
    11761 ctcattgtac cgttctgacc gcggccatac aataaaggga gcgacccgcg ctgcaattca
    11821 ggtaaaggag cacttcccat tatggttaaa catcagcaag cccccgctta tatagcggct
    11881 attttatatt cattcattat cggtttatcc tttctattcg taaaaatcgc actgcaaaca
    11941 gcagagccgt ttgatatttt ggcgcatcgg ttcaccattg cgtttgctgc ggccactgta
    12001 ccgatcttat tcggctgggt aaagctatca atccgcgtaa aggacgtcat tgccattttg
    12061 ccgctcgccc tgctgtatcc cgcgttattt ttcagctttc aggcattcgg ccttgtgtac
    12121 tcgtcctcct ctgaagcggg aattattcag gcagccattc cgattttcac gatggtcttt
    12181 gccgcttatg ttttaaagga acgcccaacg tggacgcaaa aggggttcac ggttttatcc
    12241 gttgccggcg tcatgtttat ttttgtgatg aaaggcgttg acgtggaatc agccagctta
    12301 aaagggtctt tgctgatcct attgtccgct ttgtcttcag cgatgtacaa tactgctgcc
    12361 agaaaaatga cgcagcggtt caagctgaca gagctcacct acataatgtc agccatcggc
    12421 tttgtcgtct tcaacgccat cgcccttgtg cgtcacggag cggcgggaac agtcggcact
    12481 tattttctgc cgttccggga gcccggcttc gttctcgcca ttgtgtattt gggcgtgctg
    12541 tcttcacttg tcacttcgtt tctgtctaac tatacgctgt cgcgaattga ggcgtttaaa
    12601 atgagcgctt ttaatcatgt atctaccatt gtgacgatga ttgcaggagt tgtaattctc
    12661 aaagaaagcc tggcttggta tcatcttgcc ggggctgttt gtattatgat tggcgtggtg
    12721 gggagcaata tcaatctgga gaaaaaaaca aagcgctctg gtatgcctgc aaaaaaatga
    12781 gaaattatgc tagactgaaa ggaaaaacat ggttagaggt gtaggtttac cgtatgattc
    12841 aatatgctag tgaaagtatc aatcttccag gagaaatcgc ttttaaggat gtaagagaaa
    12901 tcttttttta tcaaatcgca aaaatatcat gcttttactt tctgttgttt tgcgccatat
    12961 ttgctgcagt taacttcatt aatggatggc cccgtatcgt ttatggcagt gacgcgctta
    13021 acttgtttat gaacagtatg ttgattatcg tgatgtcagt tctgtttaca ctgctgctcc
    13081 tccttcttct atatgtgaag ttttccagag catacaagaa gaacgaacgg atgaaatcta
    13141 aaagaacata tactctgaac caagaaggaa ttcgtatatg ttctaaaaaa tatgacctca
    13201 ttttcaattg ggatgaaatc acagctgttt tcgaatataa aaatatcttc agggtcaata
    13261 catcaagtgg ccaatatatt gcgatcccaa aacgtttttt tcattccaaa gaggaaatga
    13321 acagattcaa ggggattatc cttaaaaata ccggaacaaa aaaactcaaa tttaaaaagg
    13381 atcagcattg acagtgctga tccttttata ttgaatggtg ggtttctttt gccttctgtt
    13441 tatctaaaaa cggcaccagc tctattacag ccgataaacc cacaaacacg atgcacacag
    13501 cgacaatcag caaataacca tgagtcatgt caaaaaacaa accgcccgca tacacgctga
    13561 gagctccggc aacctgatgg ataaagaaat tgatgcctaa cagcgatccg atcaatcctg
    13621 tttgatagct ttccgaaatt gacgccgcgg tcagcgggat cacgcctgtg taactgagcc
    13681 cgaataacag gataaacccg aagtaccaaa ggtcgctgtg atgaattccg agaatgggaa
    13741 tgagcaggca aatgaggctg agcagccgaa tgaaaaataa gatggatagc atgacgcttc
    13801 tgctgccgag gagatctgac agccagcccg ccaataatcc gccaatcatg ataaatgccc
    13861 cgaacgcggc catcattccg ttgacatgag agacatgcgc atccttcagt atcgggacga
    13921 ggtgagcatc aataattccc attgtaaatc cgcaagtaaa cacgccgaag tacaggatat
    13981 gaatgaggcg ggattgcttc atcacgttcc aaaacccccg ccaatcataa gattttttca
    14041 cagactccgc ttgcgcatgt ggcgggtgct tcatcccaaa gacgaggagc ggcagcagaa
    14101 cagccgccat gacgattccc aaaatggtat aggtgctctg ccagccggca tgatacggag
    14161 ccgcagccca aatgggtgag agaagcagca ggcccgcaga gttggcattg gtcaaaatag
    14221 caagcgccag acctttgtgt gtgtcaaacc aacggctgat gaaatactgg gtcgtcacgc
    14281 cgaccgcgca ggaatagccg attccgccaa gcacaccgta aatggcggaa aacacatgaa
    14341 cattcggtga ataaggaagc accaaaaagc ttgcgctgat gcagacagct ccaagcgcca
    14401 taatttttct gacactgaaa cggtcgataa aaaaaccgac aaaaaactgg acgatgccgg
    14461 ttgtgatcat aaaaatgctg acagaaaccg aaatcagcga cctgtcggca tggaaggcgt
    14521 ctgccattgg cagcataaaa aattgaaagg aatttctgaa tgagttcatt ccgatggcga
    14581 aaacaaacgt aaacagcaat acaaaccatt tcatcctggg agacgtgcgc atgtttcgac
    14641 ctgcctttgt ttgagtattt cgactattat accatgcaaa agttggcatt ctacacaaaa
    14701 aaagcggaac agccgaagct gtccgctttt gatcacggtt gaatgatcgg atgctgattc
    14761 aagatcgcaa aaatccgttc tgcgacttct tccgtttgtg acagcaggaa catgtgcccg
    14821 ccgtcaaatt gatggaatgt gatgtctttt gcccacttct tccagccttc cgcatctcgt
    14881 atgcattttt tatcatcaag cccgttaaag acatgaacag gcgactgaat ctgggccaga
    14941 tcgtaaagct caaattgttc aagagcccgg taatctgatc ggaaagaagg caggaaaaag
    15001 gacatgacct ccttattttc aacaagctct gcgggcattc cgcctaattg gataatatga
    15061 tcgagaaact gatcatcagg caggtgggac actttcttcc gctgaatatg aggcggctgg
    15121 attgcagaaa tgataaccgc ctgcggaaag acgccttcac gctcaagctt ttgcgccagc
    15181 ctgaaggtga tcattccgcc catactgtgt ccgaacagca caaacggccg atcagggcga
    15241 aggttcagtt cttgcttgta caaatccgtc agctcttcga gatcctcaat agctgacgtt
    15301 tgattcgtgc cgtgtc
//
