LOCUS       gnlProkkaKODCOHLO_48   28315 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KODCOHLO_48.
ACCESSION   gnlProkkaKODCOHLO_48
VERSION     gnlProkkaKODCOHLO_48
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 03:24:36
            Original ID  :: gnl|Prokka|KODCOHLO_48
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 28315
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     cand_cluster    1..28315
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..28315
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     protocluster    1..22434
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:2434]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..2434
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..22434
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     aSDomain        complement(2..178)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg39_1_PCP.1"
                     /evalue="2.00E-23"
                     /label="ctg39_1_PCP.1"
                     /locus_tag="ctg39_1"
                     /protein_end="811"
                     /protein_start="752"
                     /score="74.2"
                     /tool="antismash"
                     /translation="EKKLSEIWEAVLGRERVGIDENFFEIGGHSLKASMLISRIRKTFG
                     TDIKVKELFEQPTI"
     aSModule        complement(2..1690)
                     /complete
                     /domains="nrpspksdomains_ctg39_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg39_1_PCP.1"
                     /locus_tags="ctg39_1"
                     /monomer_pairings="Val -> Val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS             complement(2..2434)
                     /NRPS_PKS="Domain: AMP-binding (248-645). E-value:
                     6.2e-108. Score: 352.8. Matches aSDomain:
                     nrpspksdomains_ctg39_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (752-811). E-value: 2e-23. Score:
                     74.2. Matches aSDomain: nrpspksdomains_ctg39_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     318.3; E-value: 1.2e-96)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_1"
                     /sec_met_domain="Condensation (E-value: 1.8e-07, bitscore:
                     21.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 9.6e-119, bitscore:
                     387.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.1e-16, bitscore:
                     49.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKSIKGDKNSIGELKTEEHFLVGSKPSKEKRMKNLTYKLSQQLS
                     DKLNVCCNGSDERLHVVLTAALTLLINQYTERQNIVIKTPVFRKNRTIDSEQEILTLKN
                     AVHGEDLLKEIIHKVEFTVEQALESPQNNSRTSDKMTGLPFDVMIVLENIQEYILNQEN
                     PAIHILFSFINQKQYIETAIHYNECLYSQNMIKDLSLRFQMILEAMITPENIRVKDMRF
                     LKEKNKQKKIFGWEDNYSKIGTISEVFEQQADEYSDKTALVLENSSMCYAELNHRANQL
                     ARYLQECGVKRGDLVGIALERSFDLYISILAILKSGGAYVPLDPQYPKQRLSFLIEDSG
                     VELLITNESIQSQLPPHGDGVICLDGMKEEIEKMDGSNIGIKGSLDDLAYVMYTSGSTG
                     LPKGVSIVNRGVIRLVKETDYAVFDENQTFLQLASAAFDASTFEIWGCLLNGGCLAIMP
                     PGIPTADDIAEAVKKYNITTLWLTAGLFSLVVDQQLESLKGLQQLLVGGDVVSVPHVQK
                     VLALGKVQVINGYGPTEGTTFTCCFPVPHDWKGSTLPIGRPISGTEIFILDSQLKPVAP
                     GIPGELFIGGDGLAREYWRRPDLTKERFISHPFNNDPSARLYKTGDLVRYLENGDVEFI
                     GRRDEQVKIRGFRIELGEIEARLINHTEIKEAAVTVNHNGDDDLYICAYYTSNHKIAKI
                     ELQHFLRDFLPEYMVPSYFKQMDNMPLTVNGKIDRRALPRPDISQMSETKYEAPTNETE
                     KKLSEIWEAVLGRERVGIDENFFEIGGHSLKASMLISRIRKTFGTDIKVKELFEQPTI"
     CDS_motif       complement(470..535)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg39_1_0005"
                     /evalue="3.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg39_1"
                     /protein_end="655"
                     /protein_start="633"
                     /score="38.1"
                     /tool="antismash"
                     /translation="FIGRRDEQVKIRGFRIELGEIE"
     aSDomain        complement(500..1690)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg39_1_AMP-binding.1"
                     /evalue="6.20E-108"
                     /label="ctg39_1_AMP-binding.1"
                     /locus_tag="ctg39_1"
                     /protein_end="645"
                     /protein_start="248"
                     /score="352.8"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEQQADEYSDKTALVLENSSMCYAELNHRANQLARYLQECGVKRG
                     DLVGIALERSFDLYISILAILKSGGAYVPLDPQYPKQRLSFLIEDSGVELLITNESIQS
                     QLPPHGDGVICLDGMKEEIEKMDGSNIGIKGSLDDLAYVMYTSGSTGLPKGVSIVNRGV
                     IRLVKETDYAVFDENQTFLQLASAAFDASTFEIWGCLLNGGCLAIMPPGIPTADDIAEA
                     VKKYNITTLWLTAGLFSLVVDQQLESLKGLQQLLVGGDVVSVPHVQKVLALGKVQVING
                     YGPTEGTTFTCCFPVPHDWKGSTLPIGRPISGTEIFILDSQLKPVAPGIPGELFIGGDG
                     LAREYWRRPDLTKERFISHPFNNDPSARLYKTGDLVRYLENGDVEFIGRRDEQVKIR"
     CDS_motif       complement(623..709)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg39_1_0004"
                     /evalue="3.60E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg39_1"
                     /protein_end="604"
                     /protein_start="575"
                     /score="48.0"
                     /tool="antismash"
                     /translation="PGIPGELFIGGDGLAREYWRRPDLTKERF"
     CDS_motif       complement(1076..1102)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg39_1_0003"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg39_1"
                     /protein_end="453"
                     /protein_start="444"
                     /score="-2.9"
                     /tool="antismash"
                     /translation="WGCLLNGGC"
     CDS_motif       complement(1217..1270)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg39_1_0002"
                     /evalue="4.20E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg39_1"
                     /protein_end="406"
                     /protein_start="388"
                     /score="25.5"
                     /tool="antismash"
                     /translation="AYVMYTSGSTGLPKGVSI"
     CDS_motif       complement(1463..1504)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg39_1_0001"
                     /evalue="4.70E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg39_1"
                     /protein_end="324"
                     /protein_start="310"
                     /score="19.6"
                     /tool="antismash"
                     /translation="LAILKSGGAYVPLD"
     CDS             complement(2805..3500)
                     /NRPS_PKS="Domain: Thioesterase (2-227). E-value: 2.4e-38.
                     Score: 124.7. Matches aSDomain:
                     nrpspksdomains_ctg39_2_Thioesterase.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 222.5; E-value: 6.9e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_2"
                     /transl_table=11
                     /translation="MKKIFCLPYAGGSSAIYYKWRRLMSDSLTIHPIELKGRGTRINED
                     FYEHIDEAVNDIYDLIKDQIRECDYALFGHSMGGRLVYKLYCKIAEMQQKKPNHIFFSG
                     CGIPKTKKAEGMIHALPDNLFLQRIMDMGGTSEELLHNKELQQLYLPILRSDFKMLEKD
                     VISENKTVMDCDITVLHGINDKTISSDLICNWGHYTLGKCNFYTFEGNHFFIHQFSNEI
                     TDIINKTLR"
     aSDomain        complement(2820..3494)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg39_2_Thioesterase.1"
                     /evalue="2.40E-38"
                     /label="ctg39_2_Thioesterase.1"
                     /locus_tag="ctg39_2"
                     /protein_end="227"
                     /protein_start="2"
                     /score="124.7"
                     /tool="antismash"
                     /translation="KIFCLPYAGGSSAIYYKWRRLMSDSLTIHPIELKGRGTRINEDFY
                     EHIDEAVNDIYDLIKDQIRECDYALFGHSMGGRLVYKLYCKIAEMQQKKPNHIFFSGCG
                     IPKTKKAEGMIHALPDNLFLQRIMDMGGTSEELLHNKELQQLYLPILRSDFKMLEKDVI
                     SENKTVMDCDITVLHGINDKTISSDLICNWGHYTLGKCNFYTFEGNHFFIHQFSNEITD
                     IIN"
     CDS_motif       complement(3252..3293)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg39_2_0001"
                     /evalue="3.60E-04"
                     /label="NRPS-te1"
                     /locus_tag="ctg39_2"
                     /protein_end="83"
                     /protein_start="69"
                     /score="13.1"
                     /tool="antismash"
                     /translation="YALFGHSMGGRLVY"
     CDS             complement(3572..3745)
                     /locus_tag="ctg39_3"
                     /transl_table=11
                     /translation="MEELFGMAELIIGVLMNVFIGKIGQVAFGKDNRTTRIILRVIGIF
                     LIINGVSRAFHI"
     CDS             complement(3801..4964)
                     /locus_tag="ctg39_4"
                     /transl_table=11
                     /translation="MQLIAMIKHQLKLMLRNRLAIFATISVPLILTFLFSFSQDTDSKE
                     NLYIANADKSNYAAKLIEMIKEHKNIKVIKLTENEIKKKVDDQDIPFGVVIEKGFGKEL
                     ADNHKIKMKIIQNYENGSGTLLEQLVTNEAGTLKKVVKDSQYMSAQLHTDSKDIEKNIF
                     KKLKNNSGIEVNDKTLSQGKHTQDNATVRLIGFLVMFIWFVVIQGLRTLIDEKENNTFS
                     RLLSTPINYTKYVLSKMAATYISGIIHIIVIILAGKYLLKISIGHNIFAIAVMLAVYLF
                     ALTCITMIMVPFMRSQKQFTSAASIIIAVSGMIGGSFFSLEIAPKYMQVISKFTPEAWA
                     IQSLNNIIFSKSTLGTEWLPIVIFASVGLLSIIVSFILISREIKKEN"
     CDS             complement(4967..6175)
                     /locus_tag="ctg39_5"
                     /transl_table=11
                     /translation="MRKLFNLFFLDFKLLTKNKSFYLKLMLFPSLLILILGSVFSNSDS
                     KIEAFDVAFYSADSGESVSLGDVLKDKVFKKGDLKDIIHLKEAESYNDGEKLVKEGKAA
                     AFIYVPEHFTKAVMNNGKTNIDLIGDNNKTIDKNIVQAVLEGFTKSVKTMSAEQQEVIK
                     HISPGGSVPKEKIEKMMNDLADNDGISADIPKAATNKNAVPVDSMQYYSIAMVVMFSIM
                     TAFVLVHSIVDERQNNTLFRIKSTPTLNIQYVLGKLTGIIFAILMQMTAVILISWVVFR
                     MNWGNLFDIFVITVVYAFAIGSIVLFWGFTAKDHVAVSSMASPVLYIFSFLGGSFIPKN
                     GLPDSLRVVQEIIPNGKAINSYLKVKQNIGLSGMYIDLLELIGIGLIFVFINIMVFNRK
                     KVA"
     protocluster    5930..28315
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[15929:18545]"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      15930..18545
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
     cand_cluster    5930..28315
                     /candidate_cluster_number="3"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="2"
                     /tool="antismash"
     CDS             complement(6191..7123)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 208.5; E-value:
                     1.8e-63)"
                     /gene_kind="transport"
                     /locus_tag="ctg39_6"
                     /transl_table=11
                     /translation="MLELKKLTKKYDDFTAVNNISLTVEDGEVFGLLGPNGAGKSTMVS
                     MISTVLAPTSGTIKVDNKSLKEKPIEIKKIMGVVPQDLALYETLSAKDNLNFFGSLYGL
                     KGKKLKERTDEVLEIIELTDKKNQNVSEFSGGMKRRVNIGVALMNNPKLLILDEPTVGI
                     DPQSRNHILETVKRLNKEKGMTVIYTSHYMEEVEYLCEKVAIVDHGSLIALGTKEELKE
                     NLNACDTLTVTFKGADEEALSRINSITGIDKVTVDHKQISMLVSTKERNIIEIVDDIKN
                     LGIDLTSFKYEEVNLESIFLQITGKNLRD"
     CDS             7140..7325
                     /locus_tag="ctg39_7"
                     /transl_table=11
                     /translation="MVFRFFYFNLNGIFLEFTIVLIYLITLVTNRIVTLVIYGRCKSGY
                     IQKKMEERNLMKFLSD"
     CDS             complement(7341..7994)
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 172.6; E-value:
                     1.1e-52)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg39_8"
                     /transl_table=11
                     /translation="MDIIIVDDQQIVREGLKMILSLHEEINIVGEASNGEHLLDLLKQI
                     RPEIILMDIRMPVMDGIEATKLVKERYPDIKVIILTTFNDSEYIFTGLKSGADGYILKD
                     SDSQEIIDSIKTACEGNILLNPKVTLKVVKALNSVEHNKELVQENNEKEQLVQLLTPRE
                     KEVAKQIMEGKSNKAISEALFITEGTVKNYVSRILEKLQMNNRTELSLYLQKHM"
     CDS             complement(8018..9175)
                     /gene_functions="regulatory (smcogs) SMCOG1048:sensor
                     histidine kinase (Score: 147.8; E-value: 7.7e-45)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg39_9"
                     /transl_table=11
                     /translation="MKNLSSISTRVLIEKTIICFSLYSIISSIFKTPTFTASESAYLLI
                     ITIFLVVNDHIRLKYLSGQYSFRYYASFLVSNLLSGILLFKINCLGSQIYNIFLLIEII
                     VTTRKLPWTVVSLHFIIFFTALKAAGTSGKDILMSYLVIMAIIYLFRNVLLEKAKIQTL
                     NKELQSVNTKLKNYSQKIQELTISKERTRIAQELHDSLGHYLIALTMNLEFADKIVSKN
                     PGEAKQVINKSHDLSKECIINLREAVALLNDPAPQKGLLKSINEIFENFQQTNEIKFEL
                     DMDNKVESADPDIKNCLYKTVQESITNGIKHGNATFFSIKIRKSFEKISISITDNGTGC
                     SEINKSNGINGIEKRFAALGGEVDFYSGLDSGFTVEAVIPEIADL"
     CDS             complement(9231..9977)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 54.9; E-value: 1.5e-16)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_10"
                     /transl_table=11
                     /translation="MVYWLKKAEPGETSMSHYRTLLFDIDNTLLDFTASETDALQKLFQ
                     GSKLELTAEVEARYKALNQGLWKAFEEGEMTRDEVVNTRFALLFKEYGLEADGVLMNQA
                     YRQYLEEGHQMIDGAYELIERLSPLFDLYIVTNGVSRSQYKRLGDSGLYPFFKDVFVSE
                     DTGFQKPMKEYFDYVFARIPGFSAGHGLIIGDSLSADIKGGQMAGMDTCWFNPGKKANE
                     SGIIPTYEIHSLDELYDVLNVEVVAL"
     CDS             complement(10028..11413)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038:phenylalanine-specific permease (Score: 427.7;
                     E-value: 6.7e-130)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_11"
                     /transl_table=11
                     /translation="MANKELKRGLGARHIQMIALGGTIGVGLFMGSSSTIGWTGPSVLL
                     AYAISGIFIFFIMRAMGEMLYVEPSTGSFATFGHKYIHPLAGYMTAWSNWFQWVIVGMS
                     EIIAVGSYMKYWFPDLPAWIPGIIAMAILGAANLISVKSFGEFEFWFAMIKIVTIILMI
                     VAGIGIIFFGFGNGGHAIGLSNLWSHGGFFTNGFSGFFFALSLVVAAYQGVELIGITAG
                     EAKDPQKTLRSAIQSIIWRILIFYIGAIFVIVTVYPWNELHSLGSPFVSTFAKVGITAA
                     AGLINFVVITAAMSGCNSGIFSAGRMLYTLGVNGQAPKFFKKVSSSGVPIFGTLAVLIG
                     LVIGVVLNYIAPPKIFVYVYSASVLPGMIPWFVILISHLGFRRAKGAGLDKHPFKMPFA
                     PFTNYLTIAFLLMVLIGMWFNKDTRISLVVGVIFLAIVTVSYYAFGIGKRMPGEKSKIE
                     DAV"
     CDS             complement(11735..11839)
                     /locus_tag="ctg39_12"
                     /transl_table=11
                     /translation="MHDFCRVKQDYGVYKGEWKRVRLYAILLSKNNIG"
     CDS             complement(11839..12270)
                     /gene_functions="regulatory (smcogs) SMCOG1135:MarR family
                     transcriptional regulator (Score: 78.5; E-value: 6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg39_13"
                     /transl_table=11
                     /translation="MSKQDPIELIEYELTTFIRRAVYLDNSDRKIGHLERAAYLLLRQL
                     DEFGPARVKELAESFKLDISTLSRQAAALESKELIQRFSDPSDGRVSLFAITKLGKQRL
                     KADKKMRLERYHRMLDDWSGDEKEMFGRLLLRLNEAFID"
     CDS             12624..12869
                     /locus_tag="ctg39_14"
                     /transl_table=11
                     /translation="MIEDGAGFLLSFLPLLFIPAMTGVINYPSLFSASGAALFLIIVLS
                     TIVTMIAAGYASQLLEHKANQRKEKKKCSKHVSQSL"
     CDS             12839..13531
                     /locus_tag="ctg39_15"
                     /transl_table=11
                     /translation="MQQACIAILIILFTAAAYLAMVKLYVRFPYPFLIPVLTTTIFIIA
                     VLLVFHIPYKDYMIGGQWINSLLGPAVVALAYPLYKQRRVLIKYMFPIIGGVLAGLFSG
                     MVSGLLFAELFGISRSLILSIIPKSITTPVAIQIASGIGGVPSMTVVFVMIAGFSGVIL
                     GPLLLKWIRIRSSLGKGIAFGSASHALGTSKAMEYGELTVSMSSVSMTLCAVLGSVFGP
                     VVAWMFQI"
     CDS             13642..14487
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     184.7; E-value: 3.8e-56)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_16"
                     /transl_table=11
                     /translation="MMTGAIPQKKLLDGTSIPAIGFGTYALNGNNGVHAITSAIDIGYR
                     LIDTAYNYENEGTVGEAIRRSSVPREQLYVTSKLPGRYHDYDKAVQTIQESLYRAGLDY
                     YDLYLVHWPNPKQDRYTEAWQALIDAKKWGLIRSIGVCNFLPEHIERLERETGVKPGIN
                     QIELHPAFNQQQQRQWHEEQGIVTESWSPLSRAGEVLNDQKLGQIADKYGKTISQVILR
                     WHIQLGAIPIPKSASPERQLENISVFDFSLDGNDMNIIDSLTRPDGRINGQDPAEYEEF
                     "
     CDS             complement(14726..15568)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 69.7; E-value:
                     4.3e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_17"
                     /transl_table=11
                     /translation="MTTIKKLLELAKNPEPFEEGTQEVWLDPDRAELVLKSHFDENIPG
                     GSKGSSFVDETVDFITKIAPIECNNKIIDLGCGPGLYSQNLALKGYNVTGVDYNKKSID
                     YAISEADKMNLQIDYKIEDITNLEIESEFDVALLIYQIYGVFSPTNRRKILNNIYRGLK
                     PGGLVLLDVLSEKSYEKFEENLMWFLSKKDSLISDKEHLTLYAAIKYPDNVTLAKNVLI
                     FDDGKLVNYNYWNQHFSIENLEKEVNEAGFNLEKVYADVNGEEYKNNGEFFAAVLKKK"
     CDS             complement(15730..15867)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_18"
                     /transl_table=11
                     /translation="MNDVLELQKLEKETDGKGIAVDATITTTWTVTTTSGFVSSVSNHC
                     "
     CDS_motif       complement(15805..15867)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MNDVLELQKLEKETDGKGIAV"
                     /locus_tag="ctg39_18_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15730..15804)
                     /prepeptide="core"
                     /locus_tag="ctg39_18_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="3.30"
                     /molecular_weight="2300.5"
                     /monoisotopic_mass="2299.2"
                     /core_sequence="DATITTTWTVTTTSGFVSSVSNHC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNDVLELQKLEKETDGKGIAV"
                     /leader_location="[15804:15867](-)"
                     /alternative_weights="2318.5"
                     /alternative_weights="2336.5"
                     /alternative_weights="2354.5"
                     /alternative_weights="2372.5"
                     /alternative_weights="2390.6"
                     /alternative_weights="2408.6"
                     /alternative_weights="2426.6"
                     /alternative_weights="2444.6"
                     /alternative_weights="2462.6"
                     /alternative_weights="2480.7"
                     /alternative_weights="2498.7"
     CDS             complement(15930..18545)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 81.2;
                     E-value: 1.5e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_19"
                     /sec_met_domain="micKC (E-value: 3e-141, bitscore: 462.8,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 6.1e-20, bitscore: 62.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.5e-16, bitscore:
                     50.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGNMLYHQYLKANSEYFGKQEMTMNTYEVNDIPDTYTVISDSNS
                     VWKYYHVKGVSLPEQGWKIHLTSLLEDAQSVLDRVARFCMGKKIEFKHLKDMHSFINMN
                     SKNANRASSGKFITVYPANEEIFVELLQDLSEITKDFKKGPYILSDKRWNNTNVFYRYG
                     GFKLIFNEHGEHCIRDESGNLIKDQRTPFYQIPDFVKDFDDYLNTINHSDDSEQQGESH
                     LAKYDIITALSYSNAGGVYLATRKKDNLKVILKEARPNAGLDGGPRDALERQKIEYDTL
                     KKLKNIHGVVNLIEYFQEWEHYFLVEEFIEGRDLRQWIAQEYPFFRDEDGDSICNHAKN
                     IKKILLQLFALIDQMHNNGVAMGDLQPANVMVTEDLTVKIIDFETAMPVESEEKPSMAT
                     IGFVSQEMKAGGSRDWFGLKRLIRYLALPVLSSDDMDGYLQDNHLYWIKMNYGESFYHF
                     ILELQKKCDDKIKGYHKYLPREINLYNKKRDINLYSMINKLIKGLENNLIDDERLVNGD
                     IRQFEMNGGKFNFLTGGSGAAYILTRCNSKSENVDNWIQSFLVDNLSSGDDNGLLTGKT
                     GMLALLYEKGYKETVLNELNVLRSNVNETTNISLRSGLSGIGLFLISLYFETESKEYLE
                     FAKEIEKLIDLNKVKDESLKVNDWMAVGIGLIDGLSGVSLFYSALYSATNNKRYLEEAE
                     LFLKKDLEKTKKDDVTGVLQTLDDRNRLLPYLSGGSIGVAASIWFLNHVSGQDLFKEEF
                     RAILNLSKIRCTISGGLFDGAGSFLLIPSMVDNRKMREGILMEVMDLLNIFLIEKNDYY
                     VYPGQFSYRLSDDVYTGSSGIVLALMGIVKSNPLYWLPLVNTDKFLAETKMKDIPVGIN
                     "
     CDS             complement(18665..19318)
                     /locus_tag="ctg39_20"
                     /transl_table=11
                     /translation="MRGLLLTNYYLVYRSFFAYTGLAILVSAVIFYFGDASMHRFVAML
                     IILFVVMPALEVIKYESKSGYDRYVLTLPVSRTNIVQSHYFFYLLIVVIGAVISYGIFL
                     VYSLGSDEPIDGIFNIVSFGTFIVLFAGAIVYPLLYMIGPEKSDAIVIGGAMGGLFATF
                     GLQSVVGYAAEQVPLSFLHINPSLYVPIIYLMIGVILYIISFFIAAAIYHKKEF"
     CDS             complement(19296..20171)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 155.1; E-value:
                     4.1e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg39_21"
                     /transl_table=11
                     /translation="MMSNLLEIRNISKSFGHKAVLKDVTFNVPAGSIVGFIGDNGAGKS
                     TTFKTILGLISQDRGKVKIFGKENLNKHIKFKEDIGVVFDAMNLPAHLTIKQLNHVFKK
                     LFDAWDQDQFYQLVHSFSLPMDKKVNTFSRGMSMKLSVAVALSHNAKLLLLDEATGGLD
                     PSSRDDLLNELKSFVSKSNGGILLSSHIMTDVEKIASHIIIMKDGEILLNEEKDKVLES
                     YTVIDVDEGQLAEIDEDIVLAKRNHGSYWSVLVSDQQKLPYGVTANTISIEKISVFLTR
                     SENIERSVTD"
     CDS             complement(20796..22598)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_22"
                     /sec_met_domain="GATase_7 (E-value: 1.8e-16, bitscore:
                     51.1, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGYIGQLDAKEILLKGLEKLEYRGYDSAGIAVANEQGVHVY
                     KEKGRIADLREVVDHTVESQAGIGHTRWATHGEPSFLNAHPHQSALGRFTLVHNGVIEN
                     YVQLKREYLENVELKSDTDTEVVVQMIEQFVAGGLSTEEAFRKTLTLLKGSYAIALFDG
                     ENTDTIYVAKNKSPLLIGLGDTFNVVASDAMAMLQVTNEYVELLDKEMVIVTKDEAVIK
                     NLDGEVMTRASYIAELDASDIEKGTYPHYMLKETDEQPLVMRKIIQTYQDENGRLAVAG
                     DVADAVAEADRIYIVACGTSYHAGLVGKQYIEMWANVPVEVHVASEFSYNMPLLSKKPL
                     FIFLSQSGETADSRAVLVQVKALGHKALTITNVPGSTLSREADYTLLLHAGPEIAVAST
                     KAYTAQIAVLAILASVAAERNGVDIGFDLVKELGIAANAMEALCDQKDEMEMIAREYLT
                     VSRNAFFIGRGLDYFVCVEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVFALAT
                     QEHVNLSIRGNVKEVAARGANTCIISLKGLEDADDRFILPEVNPALAPLVSVVPLQLIA
                     YYAALHRGCDVDKPRNLAKSVTVE"
     CDS             complement(22744..22944)
                     /locus_tag="ctg39_23"
                     /transl_table=11
                     /translation="MTVLGTCCKIKLVQPLFFTCRKGGIVCIFYNYSARTKRPKNGLVD
                     EDGGYRIFGGCLPADSFRSQP"
     CDS             complement(23030..24376)
                     /locus_tag="ctg39_24"
                     /transl_table=11
                     /translation="MGKYFGTDGVRGVANSELTPELAFKVGRFGGYVLTKDKQRPKVLI
                     GRDTRISGHMLEGALVAGLLSIGAEVMRLGVISTPGVSYLTKAMDAEAGVMISASHNPV
                     QDNGIKFFGGDGFKLSDEQEAEIERLMEEPEDKLPRPTGADLGLVNDYFEGVQKYLQFL
                     KQTADEDFTGIHVALDCAHGATSSIATHLFADLDADVSTMGTSPNGLNINDGVGSTHPE
                     ALSAFVKEKKADIGLAFDGDGDRLIAVDEKGNIVDGDQIMYICAKYLKSEGRLKDDTVV
                     STVMSNLGFYKALEKEEIKSVQTAVGDRYVVEAMKKDGYNVGGEQSGHLIFLDYNTTGD
                     GLLSAIMLVNTLKASGKTLSELADEMKKFPQLLVNVKVTDKYKVEENAKVKAVISEVEK
                     EMNGDGRILVRPSGTEPLVRVMAEARTKELCDEYVTKIVDVVRTEMGAE"
     CDS             complement(24394..25833)
                     /locus_tag="ctg39_25"
                     /transl_table=11
                     /translation="MDKFLNNRWAVKIIALLLALLLYVAVNNNQAPTPKKPGESFFPTS
                     TTDEATLTDIPVKAYYDEANYVVTGVPQTVNVTIKGSTSAVKKARQTKNFEIYADMNKL
                     KTGTHKVELKAKNVSDGLTISINPSVTTVTIQEKTAESFPVEVEYYNKSKMKKGYTPQQ
                     PIISPKNVQITGSKNVIDNISLVKASVNLENANETIEKEVKVTVYDKDGNALPVDVEPS
                     VIKVTVPVASPSKKLPFKIERKGSLPDGVSVASIDSNPSEVTVYGPQDVLDSLEFIDGV
                     SLDLGKIDKDTDINADIPLPKGVTKVSPEKITLHVKVDSEDKKDFDNVAIKTVGLGGSQ
                     QIEFLDPESQAINITAKGSPANIKALKKSDIELYANVSDLDDGEHSVKLEVNGPQNVTW
                     SLSKDTVKIKLTSKKNTSSNKNDGGSADSGNKNGTSGDADKDKSKNREDDTDSDQNKSQ
                     NQDQNQDQDEDGSSADSSSTE"
     CDS             complement(25826..26335)
                     /locus_tag="ctg39_26"
                     /transl_table=11
                     /translation="MEEAQHKTIEAITKSISYMAKRRIGALIAIERDTGMGDYIETGIP
                     LNAQVSSELLINIFIPNTPLHDGAVIMKNNEIAAAACYLPLSESPFISKELGTRHRAAV
                     GISEVTDSLTIIVSEETGAISVARNGDLHRELTEEALKEMLEAEFKKNARDTSSNRWYW
                     RGKKNG"
     CDS             complement(26814..27440)
                     /locus_tag="ctg39_27"
                     /transl_table=11
                     /translation="MSCPEQIVQLMHKHLDGDILPEDENVLKQHLQSCGNCKRHFHEME
                     KSVALVRSTSHVTAPADFTAKVMANLPKEKKRASVKRWIKTHPMIAAAAVFVILMGGGF
                     FNSWHNDHNFSVSKQPNLVVQNHTVTVPEGETVKGDVTVKNGKLFIEGKVDGNVTVVNG
                     EKYMASAGQVTGQIEEINQLFDWVWYELKSAGQGVVSALDPNEDE"
     CDS             complement(27454..28017)
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 138;
                     E-value: 4.2e-42)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg39_28"
                     /transl_table=11
                     /translation="MENLIKKRIKQVKKGDQNAFAEIVDLYKDKIYQLCYRMLGNVHEA
                     EDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYYLDAEVAGAEGL
                     TMYSQIAADGVLPEDAVLSLELSDTIQKKILKLPDKYRTVIVLKYIDELSLIEIGEILN
                     IPVGTVKTRIHRGREALRKQLRDL"
ORIGIN
        1 tgatggtagg ctgctcaaaa agctccttca cctttatatc cgtgccgaat gtttttctga
       61 tgcgggaaat taacatagaa gcctttaatg aatgaccgcc gatttcaaag aaattttcat
      121 ctataccgac gcgttccctg ccaagtacag cttcccaaat ctccgaaagt tttttctccg
      181 tttcatttgt cggcgcttca tattttgttt cggacatttg agatatatca ggtcgaggaa
      241 gtgcccgtct gtcaattttc ccatttaccg tcaaaggcat gttatccatt tgtttaaagt
      301 acgatggaac catatattcc ggaagaaagt ctctcagaaa gtgctgcaat tcaatctttg
      361 cgattttatg atttgaagtg taataagcac agatatataa atcatcatca ccattatgat
      421 ttactgttac tgccgcttct ttaatttctg tatgattgat caatcgggct tctatctccc
      481 caagctcgat tctaaaaccg cggattttga cttgctcgtc ccgccgtccg ataaactcca
      541 catcgccatt ttctaaataa cgcactaagt ctcctgtttt ataaagacgt gctgaaggat
      601 cattattgaa agggtgtgat ataaaccgtt ccttcgttaa atcaggccgt cgccaatact
      661 ctcgcgccag cccatctccg ccaataaaca gctcaccagg aataccaggc gctaccggtt
      721 ttaattgcga atctaaaatg aatatttctg taccagaaat aggcctccct ataggaagcg
      781 tactgccttt ccaatcatga gggaccggga aacaacaggt aaaggtcgtt ccctctgtcg
      841 gcccatatcc gttaattact tgtacctttc caagtgctaa tactttttga acatgcggaa
      901 cggaaaccac atctccgcct accaataatt gctgaagccc ttttaatgat tctaactgct
      961 gatcaactac tagagaaaat aaaccggccg tcagccaaag agtcgtaatg ttatattttt
     1021 ttacagcttc tgcaatatca tcagccgtcg gtattcccgg aggcattata gccagacatc
     1081 ccccattcaa taaacagccc cagatctcga aggtagaagc gtcaaaagcg gcagaagcta
     1141 attgcagaaa cgtttgattc tcatcaaata ccgcataatc agtctccttc accagccgaa
     1201 tcacaccgcg gttaacaata cttactcctt taggcagtcc cgttgagcct gacgtataca
     1261 tgacataagc caggtcatcc aaggaacctt ttatgccaat attagatcca tccatctttt
     1321 caatttcttc tttcatacca tccaaacaga ttacgccgtc cccgtgaggc gggagttgtg
     1381 actgaatgct ttcgtttgta atcagcaact ctacacctga atcttcgatt aagaatgata
     1441 gtctttgctt cggatattga gggtctaacg gcacataagc accgcctgac tttaatattg
     1501 ccagaatact aatatacaaa tcaaaagagc gttctaaagc aattccgaca aggtctcccc
     1561 gttttactcc gcactcctga agataccgtg ccagctggtt cgcacggtga ttaagttctg
     1621 cgtaacacat tgaagagttt tctagtacca aagcagtctt atccgaatat tcatcagcct
     1681 gctgctcaaa cacctccgaa attgttccaa ttttcgaata attatcttcc cagccaaaga
     1741 ttttcttttg cttatttttt tctttcagga atctcatatc tttcactctg atattttcag
     1801 gagttatcat agcttcaagg atcatctgaa atcgcagtga caaatctttt atcatatttt
     1861 gagaatagag gcattcgtta tagtgtatgg ctgtctctat gtattgtttc tggtttataa
     1921 acgaaaatag gatatgaata gcgggatttt cttgattaag tatgtattct tgaatatttt
     1981 caaggactat catgacatca aaaggaaggc cagtcatttt atcacttgtt cgagaattat
     2041 tttgggggct ttccaatgcc tgttctacgg tgaattcgac tttatgtatg atctctttta
     2101 ataggtcttc accatgaaca gcatttttaa gagtcaaaat ttcttgctca gaatcaatcg
     2161 ttctgttctt tctgaaaaca ggagtcttga ttacaatatt ttgtctttct gtatattgat
     2221 ttattaacaa agtcagtgcc gctgttaata cgacatgcag acgttcatcc gatccattgc
     2281 agcatacatt cagcttatcg cttaattgct gtgacaattt atatgtaaga tttttcattc
     2341 ttttttcttt agaaggttta cttcccacta aaaaatgctc ttcagttttt aactcaccaa
     2401 tactgttttt atctcccttt atactttttg tcataacaaa aactccttca cttgatatca
     2461 aaattcaatt cattcactga attaaaacag cagaggcttt cggtggattt ttatgttaaa
     2521 ctgcatcaca ggcaataacg ctcaccaata attgttgttg tagtctgaca gtttatttat
     2581 cggcagcaaa aaccattttt taatgatata gacccgtata aacacttttt ttaaaaaaag
     2641 gataatgaag aagaactagc catctttaag aaatattata caaatattta agagttgtca
     2701 attagcaggg aaaaacacct aagcacatta acccagtttt tatttttcgt attaacataa
     2761 aaaaaccggg acaaagtaac actcccgatt tttcaatcaa caatttatct caaggtttta
     2821 tttataatgt cagttatttc attcgaaaat tgatgaataa aaaagtgatt tccttcaaac
     2881 gtataaaaat tgcatttccc taaagtataa tgtccccaat tacatattaa atctgagctt
     2941 atcgtcttgt cattaatacc atgcaacact gttatatcac agtccataac agtcttattt
     3001 tcagaaataa catccttttc taacattttg aaatcacttc ttaaaatagg aagatataat
     3061 tgttgtaatt ccttgttatg taacagttct tccgaagtcc cgcccatatc catgattctt
     3121 tgcaaaaata aattatccgg caaagcatga atcatcccct ctgctttttt cgttttagga
     3181 atgccgcatc cggaaaaaaa tatgtgattg ggcttcttct gctgcatttc agcaatttta
     3241 caatataact tataaactaa tcggcctccc atactgtggc cgaataaagc ataatcacac
     3301 tccctgattt gatcctttat cagatcatat atatcattaa cagcctcatc tatatgttca
     3361 taaaaatctt cgttaattct tgtacctctt ccttttaact caataggatg tattgttaaa
     3421 gagtcactca ttaaccttct ccatttatag tatattgcac ttgatccccc tgcatacgga
     3481 agacaaaata tttttttcat aattcacctc agaaattttg taataacccg ataaaaaaac
     3541 accctgaaaa ggatgttttt actatctcat tttatatatg aaatgctctt gaaactccgt
     3601 tgatgatgag gaagattcct attactctta aaatgatcct tgttgttctg ttatcttttc
     3661 caaaagcaac ttgcccgatt ttaccgataa atacattcat gagtacacct ataattaatt
     3721 cagccattcc aaatagttct tccataccca atttcctcac gtcctttttg atctgttaat
     3781 tttatccgat tattgttgat ttaattttct tttttaatct ccctgcttat caagatgaaa
     3841 gatacaataa tacttaataa gccgacactt gcaaaaatta cgatcggaag ccattcagtt
     3901 cctaaggtac tcttactaaa gataatgttg tttaaagact gtattgccca tgcttcgggt
     3961 gtaaatttag aaataacctg catatatttt ggagcaattt ccaatgagaa aaaggaaccg
     4021 cctatcatcc cgcttactgc aattatgatc gatgcggcag aagtaaactg cttttggctt
     4081 ctcataaatg gaaccataat catcgtaatg caggtcaatg caaataaata aacagcgagc
     4141 ataacagcga tggcaaagat gttatgacct atgctgatct tgagtaagta ttttcccgca
     4201 agtattataa cgattatatg aatgattccg gaaatataag tagcagccat tttggataaa
     4261 acatattttg tatagtttat aggcgtactt agtaatcggc tgaaagtatt attctctttt
     4321 tcatcaataa gtgttcttaa cccttgaata acaacaaacc aaataaacat tacaagaaaa
     4381 ccaattaatc tcacggtcgc attatcctga gtatgtttac cctggcttaa tgttttgtca
     4441 ttcacttcta ttcctgaatt gtttttcaat ttcttgaaaa tgttcttttc tatatctttt
     4501 gagtccgtat gcaactgcgc agacatatat tgcgaatctt taactacctt tttaagagtt
     4561 cccgcctcat ttgtgaccag ctgctctaac aatgttccgc tgccgttctc atagttttgg
     4621 atgattttca tttttatctt gtgattgtcc gccaattcct ttccaaaacc tttttcaata
     4681 acgaccccaa aaggaatatc ctgatcatcg acttttttct ttatttcatt ttccgttagc
     4741 tttataactt taatattttt atgctctttt atcatttcaa tgagctttgc agcatagttg
     4801 cttttatcag cattggctat atacaagttc tctttgctat ccgtatcttg ggaaaaagag
     4861 aacaaaaatg taaggattaa cggcactgaa atagttgcaa aaattgctaa tctatttcgg
     4921 agcatcagct tcagctgatg tttaatcatg gcaatcaatt gcactactac gccaccttct
     4981 tcctgttgaa taccataata ttaataaaga caaagatgag accaatacca attagctcaa
     5041 gcaaatcaat atacatgccg ctaaggccaa tattctgttt gacttttaaa taagagttta
     5101 ttgccttacc gttcggtatg atctcttgga caaccctcaa gctatcaggc agtccgttct
     5161 taggaataaa actgcctccc aaaaaactaa aaatataaag aaccggagaa gccatactgg
     5221 acaccgccac gtggtcctta gcggtaaaac cccaaaacaa tacaatgctg cctatagcaa
     5281 atgcgtatac taccgtaata acaaaaatat caaacaagtt gccccagttc attcggaata
     5341 cgacccagct tatcagaata acagcagtca tctgcattaa gatcgcaaaa ataatacctg
     5401 tcaactttcc aagcacatac tgaatattta aagtcggtgt agatttaatt ctgaacagcg
     5461 tattattctg ccgctcatca acaatgctat gaacaagcac aaaagccgtc ataatggaaa
     5521 acataacaac cattgcaatt gaataatact gcatggaatc gacaggaacc gcatttttat
     5581 ttgtcgctgc ttttgggata tcagcggaga tcccgtcatt atcggccaaa tcgttcatca
     5641 ttttttctat tttttctttt ggtacgctgc cgccggggct gatatgtttt attacttctt
     5701 gttgctcagc actcattgtt ttcacgcttt tcgtaaagcc ctccaaaaca gcctgaacaa
     5761 tatttttatc tatggtctta ttattatctc caattaaatc gatatttgtt ttcccgttgt
     5821 tcataacggc tttcgtaaag tgttccggta catagataaa agctgcagcc tttccttctt
     5881 taactaattt ttcaccgtca ttgtagctct cagcttcttt taaatgaatg atatctttga
     5941 gatctccttt cttaaaaact ttatccttta agacatcacc taaagaaaca ctctctcctg
     6001 aatctgctga gtaaaaagct acatcaaatg cttcgatttt tgaatctgaa ttactgaaca
     6061 cactgcccaa tatgaggatt agcagtgatg gaaacagcat cagctttaaa taaaatgact
     6121 tattttttgt taacagctta aaatcaagaa aaaataagtt gaataatttt ctcaagatag
     6181 cctcctccta ctaatctctt aggtttttcc ctgtaatttg aaggaaaatg ctttccaaat
     6241 ttacttcctc gtacttaaag ctagtgaggt cgatccccag atttttgata tcatctacaa
     6301 tttcaatgat gtttctttcc ttcgtcgata caagcattga aatttgttta tgatctaccg
     6361 tcactttatc aattcctgta atgctgttta tccggctgag tgcctcttca tcagcaccct
     6421 taaaagtaac agttaaagtg tcacaagcat ttaagttttc cttgagttct tctttcgttc
     6481 ctaaagcaat aagagatcca tgatcaacaa ttgccacctt ctcgcaaaga tactctactt
     6541 cttccatata gtggctggta taaataacag tcattccttt ttctttattc agccttttta
     6601 ctgtttcaag aatatgattt cttgattgcg gatcaattcc tacagtaggc tcatcaagaa
     6661 ttaataattt aggattattc attaacgcca cgcctatgtt gacccggcgt ttcattcccc
     6721 cggaaaactc tgatacattt tgattttttt tatctgtcag ttcaataatc tccagaacct
     6781 catcagttct ttcttttagc tttttccctt tcagcccgta aaggcttccg aagaagttca
     6841 agttatcttt ggcgcttaac gtttcatata aagctaaatc ctgtggaaca acccccatta
     6901 ttttttttat ctcaataggt ttttccttaa gtgatttatt atctacttta attgtcccgc
     6961 tggtaggtgc aagaacagtg ctaatcatag aaaccattgt tgatttgccg gcaccgttag
     7021 gacccaatag tccgaatact tctccatctt ctacagtcag cgaaatatta ttaactgccg
     7081 taaagtcatc atattttttg gtaagttttt ttaattcaag cataattaaa acacccctcg
     7141 tggtatttcg gttcttttat tttaacctga atggaatatt tttagaattt actatagtac
     7201 tcatttacct tattacttta gttacgaatc gcatcgttac tttagtcata tacggaaggt
     7261 gtaagtccgg atatattcag aagaaaatgg aggaaaggaa tttgatgaaa ttcctttctg
     7321 attgaaggaa aaaagttgaa tcacatatgc ttttgtaaat ataagctaag ctccgttcgg
     7381 ttgttcattt gaagtttttc cagtattctt gatacataat ttttgactgt gccttcagta
     7441 ataaacagtg cttcgcttat agctttgttg cttttccctt ccataatctg tttagcgact
     7501 tctttttctc tgggagtaag caattgcacc agctgttcct tttcattatt ttcttgaaca
     7561 agctctttat tatgttctac cgaatttaga gcctttacaa cttttagcgt taccttagga
     7621 tttaacagaa tattgccttc acatgctgtt ttgatggaat caataatttc ttgtgaatca
     7681 gaatctttca gtatgtaacc atcagcaccg cttttcagtc cagtaaaaat gtattcacta
     7741 tcgttaaagg ttgtcaggat aatcacttta atatccggat atctctcttt aactagcttt
     7801 gttgcttcaa tgccgtccat tacgggcatt cttatatcca ttaaaatgat ttcaggcctt
     7861 atctgtttta gcaaatctaa taaatgttca ccattagaag cttcgcctac aatattaatt
     7921 tcctcgtgca gactcagaat cattttaagc ccttccctga caatttgctg atcatccaca
     7981 atgataatat ccatatcaat acctcctcac attccgatta aagatctgct atctcgggga
     8041 ttacggcttc cacagtaaat cctgaatcta gccctgaata aaaatcaacc tctcctccaa
     8101 gtgcggcaaa tcttttttct attccgttta ttccatttga cttattaatt tcagaacatc
     8161 ctgttccgtt atcagttatc gatatagaga ttttttcaaa agacttacgt atttttattg
     8221 aaaaaaacgt agcatttcca tgttttatcc cgttggttat agactcttgt actgttttat
     8281 agagacaatt cttgatatct ggatcagctg actctacttt attgtccata tcaagctcga
     8341 attttatttc atttgtttgc tgaaaatttt caaaaatctc attgatcgat ttcagaagcc
     8401 ctttttgagg agcagggtca ttgagcaaag cgacagcttc tctcaggtta ataatacact
     8461 ccttcgataa atcatgtgac ttattgatga cttgtttagc ctcgccggga tttttactta
     8521 ctattttatc ggcgaattca agattcattg ttaatgcgat caaataatgc cccagggaat
     8581 catgaagctc ttgtgcaatt cttgtccgct ctttagaaat agttaactct tgaatttttt
     8641 gagaataatt cttaagttta gtgtttacac tttgtaattc tttatttaat gtttgtattt
     8701 ttgctttttc gagcagtacg tttctaaaca gataaataat agccatgatc actaaatagg
     8761 acatcaatat atctttcccg ctggtccctg ctgctttaag agctgtaaaa aaaataataa
     8821 aatgcagact tactacagtc cagggcagtt tacgagttgt tacaataatc tcgatcagta
     8881 aaaaaatatt atatatttga gaaccgagac agttaatttt aaacaataaa atgcctgata
     8941 aaaggttact tactaaaaaa gatgcataat atctaaaaga atactgaccg cttaggtatt
     9001 ttaatctgat atgatcgttg acgactaaaa aaatggtgat aatcagcagg taagcggatt
     9061 ccgaagccgt aaaagttggc gttttaaaaa tagaactgat aatagaatat aaggaaaaac
     9121 aaataatggt tttctctatg agcactcttg tactaattga agaaagattt ttcataataa
     9181 tccttcccga gacaacttga tataaattat attatacata tattgagaaa tcataaagct
     9241 acaacctcca cgttcagcac atcatacagc tcatcaagcg aatgaatttc atacgtcggg
     9301 ataatcccgg actcatttgc tttctttccg ggattaaacc agcacgtatc cattcccgcc
     9361 atctgaccgc cttttatgtc cgcgctcaat gaatcgccga taataagccc gtgcccggca
     9421 gaaaaaccgg gaattctcgc aaatacataa tcaaagtatt ccttcatcgg cttttgaaaa
     9481 cccgtgtcct cagatacaaa cacatcttta aaaaacggat acagaccgga gtcgcccagc
     9541 cgcttatatt gtgatcttga gacgccgttc gtcacgatgt ataaatcaaa taaaggactc
     9601 agccgttcaa tcagctcata agctccgtct atcatctggt gcccttcttc taagtattgg
     9661 cggtacgcct gattcatcag cacgccgtcg gcttcaaggc cgtattcttt aaacaaaagg
     9721 gcaaaccgtg tattcaccac ttcatcgcgg gtcatttccc cctcttcaaa cgccttccac
     9781 agcccttgat ttaacgcttt ataacgggct tccacctctg ccgtcagctc cagctttgaa
     9841 ccttggaaca atttttgaag agcatcggtt tctgaagcgg taaaatccag cagcgtattg
     9901 tctatatcaa ataataacgt acggtaatga ctcatcgatg tttcccccgg ttctgctttt
     9961 tttaaccagt ataccactcg cggacaagcc gaaaaagaca cccctgtaag agaggtgtct
    10021 ttttgaatta tacagcgtct tctattttcg atttttcacc aggcatgcgc ttgccgatac
    10081 cgaacgcata atagctgacc gtcacaatcg ccaggaaaat caccccgaca accaaagaaa
    10141 tccgcgtatc tttgttaaac cacatgccga tcaataccat gagtaagaaa gcgatcgtca
    10201 aatagtttgt aaacggcgca aaaggcattt taaacggatg cttatcaagc ccagcgcctt
    10261 tcgctcttct gaaaccgaga tggctgatca aaatgacgaa ccacggaatc attcccggca
    10321 gcacactcgc gctgtacaca taaacaaaga ttttcggagg cgcgatgtag ttcagcacga
    10381 caccgatcac aagtccgatt aataccgcaa gcgtaccgaa tatcggcaca ccgctcgaag
    10441 aaactttctt aaagaatttc ggtgcctgtc cgttcacgcc taacgtataa agcatacgtc
    10501 ccgcactgaa tatcccgctg ttgcatccgg acatcgcagc ggtaatcacc acaaagttaa
    10561 tcaaaccggc cgccgccgta atcccgactt tcgcaaatgt cgaaacaaac ggactgccga
    10621 gtgagtgaag ctcattccac ggatatacgg taacgattac gaaaatcgca ccgatgtaaa
    10681 aaatcaaaat ccgccagata atactctgaa tcgcgcttcg cagcgttttt tgcgggtcct
    10741 tcgcttcccc tgccgtaatt ccgatcagct cgaccccttg ataggccgca acaaccaaag
    10801 acaaagcaaa gaaaaatcct gaaaaaccat ttgtaaagaa accgccgtgc gaccataaat
    10861 tagataatcc gatcgcatgc cctccgttac cgaaaccgaa gaaaataatt ccgattccgg
    10921 ccacaatcat cagaataatg gtgacgattt tgatcatggc aaaccaaaat tcaaactcac
    10981 cgaaagattt tactgaaatt aaattcgccg caccgagaat ggccatggcg ataatgccgg
    11041 gaatccatgc cggcagatca ggaaaccaat atttcatata cgaaccgacg gcgataattt
    11101 cagacatccc gacgatcacc cattgaaacc agttgctcca cgccgtcata tagccggcta
    11161 acggatgtat atacttatgg ccgaatgtcg caaacgaccc tgtactcggc tctacataga
    11221 gcatttcgcc catcgcacgc atgataaaaa agataaagat acccgagatc gcataagcca
    11281 gcaggacaga cggcccggtc catccgatcg tgctggatga ccccatgaat aaaccgacac
    11341 cgatcgtgcc gcccagcgca atcatctgta tatgacgagc gcctaagcct ctctttaatt
    11401 ctttgtttgc cacttcgctt cctcctctta acagctctga tatatgtgaa ataatgaagc
    11461 agaaggtgca cctgttgaac ctaactcaat cttcatttcc cgcaatattg gaaatattct
    11521 atcttcctat cgttatataa tctccaattt ccttattcca tcataataaa ttttcgtgga
    11581 aaatacaatt gtttttttca ggcaaacacc ttacactctg aaccaacgga ctaaaaataa
    11641 agcgctttca tttttattga attgtgaata ttgagataat aaatgccgca gcctccgaga
    11701 aacattattt cccaggagaa acgttttccg ccccctatcc aatattattt ttgctaagca
    11761 gaatggcgta aagccttact ctcttccatt ctcccttgta tacgccataa tcctgcttaa
    11821 cccggcaaaa atcatgcatt aatcgataaa tgcctcattc agccgcagca aaagccggcc
    11881 gaacatttct ttttcatcgc cggaccaatc gtcaagcata cgatgatacc gctcaagacg
    11941 catcttttta tcagctttta acctctgttt gccaagcttc gtaatcgcaa acagactgac
    12001 ccgcccgtca gaaggatcgg aaaaacgctg gatcagctct ttcgactcca aggccgctgc
    12061 ctggcgtgat aatgtggaaa tatccagctt aaatgattcg gccaattcct tcacacgcgc
    12121 cggcccgaat tcatccagct gccgtaataa caaatacgca gccctttcca gatgtccgat
    12181 tttacggtcg gagttatcaa gataaacagc tctcctgatg aaagtggtga gttcatattc
    12241 aattaattca atcggatctt gttttgacaa acgcctcact ccttacattg acaacagcaa
    12301 cattagttgt ataatacaaa catatgcaca tttactcaga aaacatatag aaagattttg
    12361 catacatata tttgtatagt acaaatatat gtgccaaaag taaagaaact tatagaaaca
    12421 tcaagaaagg gggaagctgc tcttctccaa agaacagcat cgttgtgaaa gtcatacgca
    12481 tcatcttgca aatcattatt ttattcgcat tttcctttat cgggggagcc gttcagcagt
    12541 tctttcacct gcccattccc ggaagcatca tcggtttgat cctgctgatc atatgtttat
    12601 cggttaagat cattcccgtc aaaatgattg aagacggagc cggatttttg ctgtcttttc
    12661 ttccgctgtt attcattccg gccatgacgg gcgtcatcaa ttacccgtca ctgttttccg
    12721 ccagcggggc tgctctgttt ctgatcatcg tgctgagcac catcgtcaca atgatcgccg
    12781 cagggtacgc cagccagctg ttagagcata aagccaatca gagaaaggag aaaaagaagt
    12841 gcagcaagca tgtatcgcaa tccttataat tttgttcacg gccgccgcct atctggctat
    12901 ggtgaaatta tatgtgcgct ttccataccc ctttctcata ccggttttga cgactacgat
    12961 tttcattatc gccgtgctgc ttgtttttca tattccgtat aaagactata tgatcggcgg
    13021 acaatggatc aattcactgc tcggccccgc tgtggtggct ttggcatacc cgctttataa
    13081 gcagcgccgg gtgttaatca agtatatgtt tccgatcatc ggcggcgtgt tggccggttt
    13141 attctccgga atggtcagcg gcctgctatt tgcagagctg ttcggcatca gccggagttt
    13201 gattttgtca attatcccaa aatcaattac gacgcctgtc gccatacaga ttgcgtccgg
    13261 tatcggcggt gtcccttcca tgacagtcgt gttcgtcatg atcgcagggt tttccggcgt
    13321 tatcttagga ccgctgcttc tcaagtggat ccgcatccgc agctcactcg ggaaaggaat
    13381 tgcattcggg agcgcctccc atgcgctcgg cacctcaaaa gcaatggagt acggagaatt
    13441 aacggtctcc atgagttctg tttccatgac gctctgcgcc gtgttagggt cggtcttcgg
    13501 ccccgtcgta gcatggatgt ttcaaattta aagccggcgg ttctccgtca gcttttttca
    13561 tgtgcggatc atctcatttc cttccattat tatgtttcat ttgtaagaat aatggtaaag
    13621 tagaaaacaa ggagggattt aatgatgact ggggcaattc cgcaaaagaa actgcttgat
    13681 gggacaagca ttcccgcgat cggcttcggt acatacgctc ttaatggaaa caatggcgtt
    13741 catgccatta ccagcgccat tgatatcggc taccgtctga ttgacaccgc ttataactat
    13801 gaaaatgaag ggacggtcgg agaagccatc cgcagaagct ctgttccgag agaacagcta
    13861 tacgtgacgt ccaagctgcc cgggcgctac catgactatg acaaagctgt acaaaccatc
    13921 caagaatctt tataccgcgc cggtctggac tactatgacc tgtatctcgt ccattggccg
    13981 aatccgaaac aagaccgcta cacggaagca tggcaggcac tgattgatgc gaaaaaatgg
    14041 ggcctgatcc gatccatcgg cgtctgcaat ttcctgcctg agcacatcga acggctcgaa
    14101 cgtgaaaccg gtgtaaagcc aggcatcaac caaattgaac tgcatcccgc ttttaatcag
    14161 cagcagcagc gccaatggca cgaagaacag ggcatcgtga cagaatcatg gagtccgtta
    14221 tcccgcgccg gcgaagtatt gaacgatcaa aaactcggac agattgcgga caaatacggc
    14281 aaaaccattt ctcaagtcat tttgcgctgg catatccagc tgggcgccat cccgattcca
    14341 aaatcagcat cgcccgagcg ccagcttgaa aacatctctg tctttgattt ctcccttgat
    14401 ggaaacgaca tgaacatcat cgactcgctt acccgccccg acggacgcat aaacggccaa
    14461 gacccggcgg agtatgagga gttttaagaa aacacataaa gaaaagctga cggcatcatt
    14521 cgtcagcttt tttctgaatc tttatctagt tctcgctaac aaacacaatg tacgatttca
    14581 atatggctta aaggcctatc aattttaaca ctcagtgtta gagccataag gagtacacct
    14641 ttcatctatt atggctaaca ctgaatccta aatggaatat ttattttaag tactcaactc
    14701 ggctattttt agatacgttt agtccttatt ttttctttaa gacggctgca aaaaactctc
    14761 cgttattttt atattcctcg ccattgacat ctgcatagac tttttcaagg ttaaaccctg
    14821 cttcattcac ttctttttct aaattttcaa tgctaaaatg ctggttccaa taattataat
    14881 tcactaattt cccatcgtca aaaatcaaaa cattttttgc caaagtaaca ttatcaggat
    14941 atttaattgc agcgtataag gtcaaatgtt ccttatccga tatcagactg tccttttttg
    15001 ataggaacca cattaaattc tcttcaaatt tttcataact cttctctgat aagacatcta
    15061 atagaactaa tcctccaggt tttaaaccgc gatagatgtt gttaagtatt tttcttctgt
    15121 tggtcggact aaaaacacca tagatttgat aaatgagcag agctacatca aattcacttt
    15181 cgatttcgag attcgtaata tcttcaatct tataatctat ttgtaaattc attttatccg
    15241 cttcactaat agcataatcg attgattttt tattataatc tacaccagtc acgttgtagc
    15301 cttttaatgc taaattttga gaatagagcc ccgggccaca tcctaagtca ataattttat
    15361 tattacattc tattggtgct atttttgtaa taaaatccac agtctcatca acaaatgagc
    15421 tccctttgct gccgccgggt atattctcat caaaatgtga tttcaaaaca agttcagctc
    15481 tatctggatc aagccatacc tcttgtgtgc cttcttcaaa tggttcaggg ttttttgcca
    15541 attctaataa ctttttaatt gttgtcacct tctatagttt tttcatgatt tgttaattat
    15601 aattaagaac tcttgggtgc tgattttaac tacaagcacc caagaaatga taaacttaag
    15661 gcttctccga cagtccaata cagtgttcat catttatact tcattaatat ttaatgaagc
    15721 aagattgttt taacaatgat tacttactga agaaacaaaa ccgctagttg ttgttactgt
    15781 ccatgtcgtt gtaattgtcg catccacagc tataccttta ccatctgtct ctttctctaa
    15841 cttttgcaat tccaaaacat cattcacttt tctcacctcc tttcgagtgt taacagacat
    15901 tcatttatca tctaatgggg ataatattat caatttattc caactggaat atctttcatt
    15961 tttgtttccg ctaaaaattt atctgtgttg accaatggta accaataaag tggattgctt
    16021 ttaacaattc ccattaatgc taacactata cctgagctgc ctgtataaac atcatcagat
    16081 aatctataag aaaattgccc cggataaaca taataatcat ttttctcaat taaaaagata
    16141 ttaagcagat ccattacttc cataagaatt ccctcccgca tttttctatt atcaaccata
    16201 gaagggatta aaaggaagct tcctgcacca tcaaataaac ctccactgat tgtgcagcgt
    16261 atctttgata gatttaaaat ggctctaaat tcttctttaa atagatcttg tccacttaca
    16321 tggtttaaaa accaaattga cgcagcgact ccaatagacc ctccagagag atatggcaat
    16381 aatcggtttc tatcatctaa agtctgtaat acaccggtta catcatcttt ttttgtcttt
    16441 tccaagtctt tctttaaaaa taactcagct tcctctaaat atcttttatt attggttgct
    16501 gaataaagcg ctgaataaaa cagagagacg ccagataacc catcaattaa acctatacct
    16561 accgccatcc agtcattaac ttttaatgac tcgtctttaa ccttatttag gtcaatcaat
    16621 ttttctatct ctttcgcaaa ctccaagtat tctttacttt ccgtctcaaa atataaactg
    16681 attaagaaca ggcctattcc tgaaagacct gatcgtaaag aaatgttggt tgtttcattt
    16741 acattacttc tcagaacatt caattcattt aaaacagttt ccttgtaccc cttctcataa
    16801 agcagagcca gcattcctgt ttttccagtt aataaaccat tatcatcgcc actcgatagg
    16861 ttatccacca aaaaactttg aatccaatta tctacattct cagacttcga gttacatctg
    16921 gtaagaatat aggcagcgcc actcccccca gtgagaaagt tgaattttcc tccgttcatt
    16981 tcaaactgac gaatgtcacc gtttacgagc ctttcatcat ctattaaatt gttttctaga
    17041 ccctttatca acttattaat catggaatat aagttgatat cccttttctt gttataaagg
    17101 ttaatctctc ggggaagata tttgtgataa ccttttattt tatcatcaca ttttttttgc
    17161 aactctaaaa tgaaatgata aaatgattct ccataattca tctttatcca gtataaatgg
    17221 ttatcttgca gatacccatc catatcgtct gaagagagca ctggcagggc taaatatctt
    17281 attaatctct ttaacccaaa ccagtctcta gaaccacctg ccttcatttc ttgagaaaca
    17341 aacccgattg ttgccatact aggtttttct tcagactcta cgggcattgc agtctcaaaa
    17401 tctattatct taacggttaa gtcttcagtt accatcacat ttgctggctg caaatcaccc
    17461 atagcaactc cgttattatg catttgatct atcagagcaa agagttgtaa caatattttt
    17521 tttatattct tagcatgatt acatatacta tcgccatctt catctctaaa gaatggatac
    17581 tcttgtgcaa tccattgtct caaatctctt ccttcaatga attcctctac taaaaagtaa
    17641 tgttcccatt cttggaagta ctcaattaga ttgaccacgc catgtatgtt cttaagcttt
    17701 tttaaagtat catattcaat tttttgcctt tctaacgcat ctctgggtcc tccatctaaa
    17761 ccagcatttg gtctggcttc tttaagaata actttcaagt tatctttctt tcgagtcgca
    17821 agatataccc cccctgcgtt actgtagctc agtgcagtaa tgatatcata cttcgctaaa
    17881 tggctttccc cctgttgttc tgagtcgtca gaatgattga tcgtattaag ataatcatca
    17941 aagtctttta caaaatcagg gatctgataa aagggtgttc tttgatcctt aattaaatta
    18001 ccactttcat ccctaataca gtgctcacca tgttcattaa aaataagctt aaatccgcca
    18061 tatctgtaaa atacattagt attattccac ctcttatcac tgagtatata gggacctttt
    18121 ttgaaatcct ttgttatttc agataagtct tgcaacaatt caacaaagat ttcttcatta
    18181 gccgggtaca ccgttataaa tttgccggaa gaagctcgat ttgcattttt tgaattcatg
    18241 ttaataaaac tatgcatatc ctttaggtgt ttaaattcaa ttttcttacc catacaaaag
    18301 cgggcaaccc tatccaatac actttgtgcg tcctctaaca atgaagttaa atgaattttc
    18361 cacccctgct ctggtaacga tacaccctta acatgataat atttccatac tgagttacta
    18421 tctgagataa cagtatatgt atcagggatg tcattcactt catatgtatt cattgtcatc
    18481 tcttgtttcc cgaaatactc ggaattcgcc ttcagatatt gatgatatag catgttgcct
    18541 tccataaaag cccccccatt tttatatact aaatattaac cctcaaggtc acaaagttct
    18601 ttatatgcaa agacaacacc ttatcctgtt ataacttgat cagcataaaa tcaatacaca
    18661 cgcgctaaaa ttctttttta tgatatatag ctgcggcgat gaaaaatgaa atgatatata
    18721 agataacgcc gatcatgaga tatataatcg ggacatataa agaaggattt atgtgcaaaa
    18781 atgacagcgg tacttgttct gctgcatacc caacgacact ttgtaatcca aaggtagcaa
    18841 aaagtccccc cattgcccct ccaatcacga tagcatcgga tttttccggg cctatcatgt
    18901 agagaagagg ataaacgatt gcaccggcaa agagaacgat gaacgttcca aaagagacaa
    18961 tattaaatat accgtcaatt ggttcatcag aacccaggct gtatacaagg aaaataccat
    19021 aagatattac agctccgatc acaacaatca aaagataaaa gaaatagtga ctttgaacaa
    19081 tatttgttct gctgaccggt aaagtcagaa catacctgtc atagcctgac ttgctctcat
    19141 actttataac ctcaagtgcg ggcataacga caaacaaaat aatcagcata gcaacaaaac
    19201 gatgcattga agcatcccca aaataaaaaa tgactgctga taccaatatg gccaaccccg
    19261 tgtatgcaaa gaaactccga taaaccaagt aatagttagt cagtaacaga cctctcaatg
    19321 ttttcactcc tcgttaaaaa gacgctgatt ttttctatgg aaatggtgtt ggccgttacg
    19381 ccataaggca atttctgttg atccgataca agcacactcc aataagatcc atgattcctt
    19441 tttgctagaa cgatatcttc gtcaatctca gccaattgac cttcatcaac gtctataacg
    19501 gtatagcttt caagaacctt atctttctct tcatttaata aaatttcgcc atctttcata
    19561 ataatgatat ggctggctat cttctcgaca tcagtcataa tgtgcgatga aagtaaaata
    19621 cctccgttgc ttttactcac aaagcttttt aattcattta acagatcatc tcttgaagag
    19681 ggatcaagcc ctcccgttgc ttcatccaga agtaataatt ttgcattatg cgacaaagca
    19741 acagctacag ataacttcat tgacatgccg cgcgagaatg tattcacttt tttgtccata
    19801 ggtaaagaga aagaatgaac caactggtaa aattgatctt ggtcccaagc gtcgaacagt
    19861 ttcttaaata catgattcag ctgctttatc gtaaggtgcg caggaagatt catcgcatca
    19921 aatacgaccc caatatcttc tttaaacttt atatgtttat tcagattctc tttaccaaag
    19981 attttcactt tacctctatc ctgagaaatt aatcctaata tcgttttaaa tgttgttgac
    20041 ttgcctgcgc cgttatcacc gataaaaccg acaattgatc cggcaggcac attgaatgta
    20101 acatccttta aaacagcttt atgaccaaaa gatttgctga tgtttctgat ttctaaaagg
    20161 tttgacatca ttccactcct atcattgttg tcaggacttt tttaagaatt gaaccggatt
    20221 attgcaaaaa tgttgtgatt ttcatatctg gtctaggtat tcataatgga tcaggagtcg
    20281 ggaaatacaa aagggatttt aaagtcttaa gcataatatg gaagtgtaat cgattgatta
    20341 ggtttatata atgggatatt catgatgaaa actgctggag gtgacttaca tgctggaaaa
    20401 gaaaatgtgt attctataat ctatatatgt agtctcatca gataacagat ttattgtcta
    20461 attgagtagc ccgttcaaga gtgaagtatg tccaagtaat cagacatggg aataaaacac
    20521 caaacaaata cttattcaaa aaccaatatt tgatcgctac cattctttac taatggttac
    20581 atttatgggt ttaaactgga atatatttat attataaaat aggcgttact tcttttcaat
    20641 atatatatgg ggatttcttt ataaatataa aattcttcag tttatcaaca ggcgaacact
    20701 tcttattttc atactaaaaa cccctctggt ttatctaaaa ccagaggggt caaactttcc
    20761 gactatattt taagtttatc gtgaattatt tattcctatt ccacagtcac actcttcgca
    20821 aggttgcgcg gtttatcaac gtcacagccg cggtgcagtg cagcgtagta agcgatcagc
    20881 tgcaatggca caacagatac cagcggagca agcgcagggt tgacttccgg caggatgaat
    20941 ctgtcgtctg cgtcttctaa gcctttcagc gagatgatgc aagtgttggc gccgcgggct
    21001 gcgacttcct tcacgtttcc gcggatgctc aggttgacgt gttcttgtgt cgcaagcgca
    21061 aagaccggtg ttccttcttc aatcagagcg attgttccat gcttcagctc gccgccggcg
    21121 aagccttccg cctggatgta agaaatctct ttcagcttca gggcgccttc gacacatacg
    21181 aagtagtcaa ggccgcgtcc gatgaagaaa gcgtttcttg aaacagtcag gtactcacgc
    21241 gcgatcattt ccatttcgtc cttctgatcg cagagggctt ccatggcgtt tgccgcgata
    21301 cctaattctt tgactaaatc aaaaccgata tcaacgccgt tgcgttctgc tgcaacggac
    21361 gcaaggatcg cgaggacggc aatctgagcc gtatacgctt ttgttgatgc cacggcgatc
    21421 tcagggcctg cgtgcagaag caatgtgtaa tccgcttcac gggaaagcgt tgatcccgga
    21481 acgtttgtaa tcgtcagcgc tttgtgaccc agcgctttga cttgaacaag cacggcgcgg
    21541 ctgtccgctg tttctccgct ttgagaaagg aagataaaga gcggcttctt agacagaagc
    21601 ggcatgttgt aagagaattc actcgctaca tgcacttcaa ccggtacgtt tgcccacatt
    21661 tcaatatatt gtttcccgac aagaccggcg tgatagctcg ttccgcaagc cacgatataa
    21721 atgcggtccg cttccgccac ggcgtcagcg acatcgcccg ccacggccag tctgccgttt
    21781 tcgtcctgat acgtttggat gattttgcgc ataacaagcg gctgctcatc cgtttctttt
    21841 aacatgtagt gagggtatgt gcctttttcg atatcactgg cgtcaagctc agcgatataa
    21901 gacgcacgtg tcatgacttc accgtcaaga tttttaatca cggcttcgtc ttttgtcacg
    21961 atcaccattt ctttgtccaa aagctcaacg tattcattcg ttacttgaag catagccatc
    22021 gcgtcagatg ccacgacgtt aaacgtatct ccaaggccga ttaacagagg gcttttgttt
    22081 tttgcaacgt aaatggtgtc tgtgttttca ccgtcaaata atgcaattgc gtaagagcct
    22141 tttaacagag tcagtgtttt gcggaacgct tcttctgtgc tgagtcctcc cgccacaaat
    22201 tgctcgatca tttgaacgac tacttcagtg tccgtgtcgc ttttcagttc aacgttttca
    22261 agatactcgc gcttcagctg aacatagttc tcgatcacac cgttatgaac aagtgtaaag
    22321 cggccgagtg cgctttgatg cgggtgagcg ttcaggaagc ttggttcgcc gtgagtcgcc
    22381 cagcgtgtat ggccgattcc cgcttgagat tcaaccgtgt gatccaccac ttcacgaagg
    22441 tcggcgatgc ggcctttttc tttgtacaca tgcacgccct gctcattcgc cacagcgata
    22501 ccggcagagt catagccgcg gtactcaagc ttctctaatc cttttaacaa aatctctttc
    22561 gcatcaagct gaccgatgta acctacaatt ccacacatat tttcttcctc ctaaaggtgt
    22621 aaaaggagac gaagaaagtc aaattacaag gggactttca atcgtcccct cccacatgtt
    22681 tttttggaag atcatgtgat ttccctttgt tcggagagtc gcccctccgg tttgaagaaa
    22741 tccttacggc tgtgatctaa atgaatcagc cgggaggcat ccgccgaaaa ttcgataacc
    22801 tccatcctcg tcaactaagc cgtttttcgg gcgcttagtt cgggcgctgt aattataaaa
    22861 gatgcaaaca atcccgcctt tcctgcaagt gaaaaacaaa ggctgaacaa gcttgatttt
    22921 acaacatgtg ccaaggacgg tcaattattt tttgccgccc cggcatcatg tttactatca
    22981 ttttatgctg atcgcacttg tcttgttcgc tctctgctta taaacttcgc tactccgctc
    23041 ccatttctgt ccgcacgaca tccacgattt ttgtgacata ttcgtcacaa agctcttttg
    23101 ttctcgcttc cgccatcacg cgtacgagcg gttcggtgcc tgacgggcgc actaaaatcc
    23161 ggccgtctcc gttcatttct ttttccactt cagaaatcac ggccttcacc ttagcgtttt
    23221 cttctacctt atatttatcc gtcactttca cgttcactaa gagctgcggg aattttttca
    23281 tttcatccgc aagttctgaa agggttttgc cggacgcctt cagcgtattc acaagcatga
    23341 tcgcggacaa aagaccgtcg ccggtagtgt tgtaatcaag gaaaataagg tgccctgact
    23401 gctcgccgcc gacattatag ccgtcttttt tcatcgcttc tacgacatag cgatcgccga
    23461 ctgccgtttg aacgcttttg atttcttctt tttcaagcgc tttgtagaaa ccgaggttgc
    23521 tcatcacggt cgatacgacg gtatcatcct tcagacggcc ttctgatttc aaatacttcg
    23581 cgcatatgta catgatctga tcgccgtcga cgatgtttcc tttttcatca acggcaatga
    23641 ggcggtcgcc gtctccgtca aacgcaaggc cgatatcggc ttttttttct ttgacgaaag
    23701 cactcagcgc ttccgggtgt gtagaaccga cgccatcatt aatgtttaat ccgttcggag
    23761 acgtccccat tgtagatacg tcagcatcga gatcggcaaa aaggtgcgtc gcaatggaag
    23821 atgtcgcacc atgggcgcag tcaagcgcta catgaatgcc tgtaaaatct tcgtccgccg
    23881 tctgttttaa aaattgcaga tacttttgaa cgccttcaaa ataatcgttc acaagcccga
    23941 ggtccgcgcc tgtcggtctc ggcagcttat cttccggttc ctccatgaga cgttcaatct
    24001 cggcctcctg ctcatcagaa agcttaaagc cgtcccctcc gaaaaattta attccgttat
    24061 cctgtacggg gttgtgagaa gcggagatca tgacgcccgc ctcagcatcc atggctttcg
    24121 ttaaatagga tacccccggc gtagaaataa cgccgaggcg catcacttca gctccgatcg
    24181 ataaaagtcc ggcgacaagg gctccctcca gcatatgtcc ggagatacgt gtatcacggc
    24241 cgatcagcac tttcgggcgc tgcttatctt tggtcaggac ataaccgcca aaacgcccca
    24301 ctttaaaggc cagctctggc gtaagctcgc tgttggcaac acctcttaca ccatctgttc
    24361 caaaatactt gcccattttg tatcgctcct ttttcattct gttgaagaag aatcagcgct
    24421 tgatccgtct tcatcctggt cttgattttg atcctggttt tgacttttat tctgatcgct
    24481 gtcagtgtcg tcttcccggt tcttgctctt gtctttgtct gcgtctccgc ttgtgccgtt
    24541 cttattgccg gaatcagcgg agccgccgtc atttttattt gaacttgtgt ttttcttaga
    24601 agtcagcttg atcttaaccg tgtcttttga cagggaccat gtgacgtttt gcgggccgtt
    24661 tacttcaagc tttacagagt gctctccgtc atccaagtcc gagacattgg catacagttc
    24721 aatgtccgac tttttcagcg ccttaatgtt ggcgggagag cctttggccg taatatttat
    24781 cgcctgcgat tcagggtcga gaaactcaat ctgctgtgag cctcccagtc cgaccgtctt
    24841 gattgcgaca ttgtcaaaat cctttttgtc ttcactgtcc actttaacat gaagcgtgat
    24901 tttttccggt gataccttag tgacgccctt aggaagcggg atatcggcat tgatatcggt
    24961 atctttatca attttgccta aatcaagaga tacgccgtca ataaattcca gtgaatccag
    25021 cacatcctgc gggccgtaaa ccgtcacctc actcggattc gagtcaatgc tcgcaacgct
    25081 caccccgtcc ggaagacttc ccttcctttc gattttgaaa ggaagctttt tgctcggact
    25141 ggctacggga accgtcactt taatgactga cggttcaaca tcaacaggaa gtgcgttgcc
    25201 gtctttgtca tagacggtca ccttcacttc cttttcaatg gtctcatttg cattttcaag
    25261 gttcacggat gctttgacaa gtgaaatgtt atcaatcaca tttttcgaac ctgtaatctg
    25321 cacgtttttc gggctgataa tcggctgctg aggggtatat ccctttttca ttttgctttt
    25381 attgtagtat tcaacttcca cgggaaaact ctcagccgtt ttttcctgaa tcgtaaccgt
    25441 cgtgactgat gggttaatgg agatcgtcag tccgtccgat acgttttttg ccttcaattc
    25501 gaccttatga gtcccggtct tcagcttatt catatcggcg tatatctcaa aattcttcgt
    25561 ctgtctcgcc tttttcaccg cgcttgtcga gcctttaatc gtgacattta ccgtctgggg
    25621 cacgccggtg acgacatagt tcgcttcatc gtagtatgct tttacaggaa tatcagtaag
    25681 cgtagcctcg tcagtcgttg atgtcggaaa aaaggattcc cccggctttt tcggagtcgg
    25741 cgcctggttg ttgttaaccg caacgtaaag cagcagcgcc aagagcaatg caatgatctt
    25801 tacagcccag cggttgttta agaatttatc catttttctt gcccctccag taccagcggt
    25861 tagaagaagt gtctctggcg ttcttcttaa actcggcttc aagcatttct ttcagtgctt
    25921 cttccgtcaa ttctctgtga aggtctccgt ttctggccac actgatggcg cccgtctctt
    25981 cagatacaat aatggttaag ctgtccgtca cttcactgat gccgacagcc gctctgtgac
    26041 gcgtccccag ctcctttgaa ataaacgggc tttcagaaag cggcagataa caggcagccg
    26101 cagcaatctc gttatttttc ataatgaccg ctccatcatg cagcggtgta ttcgggatga
    26161 agatattaat caaaagctcc gagctgacct gcgcattaag cgggatgccc gtctcaatat
    26221 aatcgcccat tcccgtatcg cgctcaatgg cgatgagtgc gccgatgcgg cgtttcgcca
    26281 tgtagctgat cgattttgta atcgcttcaa ttgtcttatg ctgcgcttcc tccacagggg
    26341 ttccgctcct ggaaaagaac cggccccgtc cgagctgttc aagcgcccgt ctcagctcag
    26401 gctggaatat aatgatgatc gctaaaaatc cccatgttat cgcttggtcc atcagccact
    26461 gaagcgtgct gagtcccaaa tatgaactgg ccatccggac caatacgatg acgacgattc
    26521 cttttaaaag ctgaaccgcc ttcgtcccgc gtatgaccat gattaattta tatatcacat
    26581 accaaacaag gagaatatca acggcattgc cgaggtattg caaaaatggg atgtcctcaa
    26641 aagccatttc ctcgtcctcc aagaattcag tcatttcgtt tttttcgtta tgaattgtgc
    26701 tgcatgagca atatgtacat catatagcgt gctcattata ccacattttg atttctcaag
    26761 tgaaatgagc cggcgcggcg ttgcacaaaa aaagagtaaa gcgattatac gctttactca
    26821 tcttcattcg ggtccaaagc gcttacgacg ccctgtcccg ccgatttcag ttcgtaccag
    26881 acccagtcaa acaattggtt aatctcttca atctgcccgg tgacttgtcc ggctgaggcc
    26941 atgtattttt ctccgttgac gacggtcaca ttgccgtcga cttttccttc aatgaacagc
    27001 ttgccgtttt ttactgtgac atcgcccttt acggtctcgc cttcagggac ggtgaccgtg
    27061 tgattctgca cgacaaggtt cggctgtttg gacacactga aattgtggtc attatgccag
    27121 ctgttgaaaa aaccgccgcc cattaaaatc acaaaaaccg ctgcggctgc aatcatcgga
    27181 tgagttttga tccatcgttt tacagaagcg cgttttttct cttttggaag attcgccata
    27241 actttggcag taaaatcagc aggggccgtg acatgcgatg tgcttcggac gagtgctacg
    27301 gatttctcca tttcatgaaa atgccgtttg caattcccgc atgactgcaa atgttgtttt
    27361 aatacgtttt catcttcagg aaggatatct ccatcaagat gcttatgcat aagctgcaca
    27421 atctgttcag gacagctcat ttcatcaccc cacttaaaga tccctcaatt gttttctaag
    27481 agcctctctg cctctgtgta tccttgtctt gacggtgccg acagggatat tcagaatctc
    27541 cccgatttca attaaagaga gttcgtcaat atactttaat acaataaccg ttctgtactt
    27601 gtcaggcagc tttaaaatct ttttctgaat tgtgtccgac agctccaatg acaatacggc
    27661 gtcttcaggg agaaccccgt ccgcggcgat ctgcgaatac atcgtcagcc cttctgctcc
    27721 cgctacttct gcgtccagat agtaatcagg ctttttcttg cggatacggt caatggtcag
    27781 gttggtcgca attctgtaaa gccacgttga aaactttctg ttgatatcga aactgtcgat
    27841 attgacatac gctctgataa aagcttcctg cgcaatatct tccgcttcgt gcacattgcc
    27901 gagcatgcgg tagcaaagct ggtaaatctt atctttataa aggtcaacga tttctgcaaa
    27961 cgcattttga tcgccttttt tgacttgctt gattcttttt ttaatcaggt tttccatgtt
    28021 ttatcttacc tctgcccttc accggtctgt atctatacgt tgattgtttt aaaaggtttc
    28081 atttttttat tacatttatt ttaccaaatt tcaggcaggg tgtagatgga aaatacagaa
    28141 tatactgcct taacagcagc ttaaaaatag tatatctgat gaacaatcaa aaatcgaaac
    28201 aaaatgccga taaaaaaaga cacctttatg caaaaggtgt ctgagactgg gctagctgga
    28261 ttcgaaccaa cgcatgacgg agtcaaagtc cgttgcctta ccgcttggct atagc
//
