LOCUS       gnlProkkaKODCOHLO_84    3062 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KODCOHLO_84.
ACCESSION   gnlProkkaKODCOHLO_84
VERSION     gnlProkkaKODCOHLO_84
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 03:24:36
            Original ID  :: gnl|Prokka|KODCOHLO_84
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3062
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3062
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:3061]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..3061
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3062
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3062
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(2..3061)
                     /NRPS_PKS="Domain: PCP (43-111). E-value: 1.8e-19. Score:
                     61.6. Matches aSDomain: nrpspksdomains_ctg62_1_PCP.1"
                     /NRPS_PKS="Domain: Heterocyclization (133-428). E-value:
                     7.6e-90. Score: 293.2. Matches aSDomain:
                     nrpspksdomains_ctg62_1_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (591-982). E-value: 2.3e-98.
                     Score: 321.3. Matches aSDomain:
                     nrpspksdomains_ctg62_1_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     144.7; E-value: 8.1e-44)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg62_1"
                     /sec_met_domain="PP-binding (E-value: 1.7e-17, bitscore:
                     50.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.6e-55, bitscore:
                     173.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1e-108, bitscore:
                     349.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVQIEEVPLTSNGKVDRKKLLALDVTDQASIGRKIKEPRTEIER
                     DLVDIWKSVLKTDEISIDDNFFELGGNSILIINLITAIEDRLFIKLDFKNFISNSTIEK
                     LAKVISVSERKSKTNSNVMEIQADIKNKNTEFDLTNVQMAYLMGRDKQFELGGTSTHAY
                     LEIETELNIEKLNKSLQKVIDYQDMLRAVVLPNGRQKILQQVPQYEISVQDISQLSDIE
                     QEKKIVEERDRTSHRIFNPNEWPLFEFKALKIQGDKHRLFFGIDMLIADGASIQLLFKQ
                     ISEFYNGKDEMVPLEISYRDYMLAYQKVKTTHKYENDKAYWLSQLEDFPKAPAVPLKER
                     LDAISKPTFNRKSKIIDKPLWETFCKKAASYNITPAIILFTAYAKVLSKWSNQQNLAVN
                     TTVFNRQPFHKQVNDIIGDFTSLIMLKASFEKKMNFWEEAKKVQVTFMEALEHRDYDGV
                     EFIREYAKYNNLNHKSATMPVVFTSMLFGNMFNLNNNDLLNIGELKMAISQTSQVYLDH
                     QVIELNDGVMLSWDYVSEAFENDVIESMFEEYTHIIDQLTSGEKMSSGDTALEQAITDY
                     NQTEKAIKPDTLYHLFARQTVKTPENVAIECQGRAVTYQELQGMSNRISSFLEEKGIQP
                     NEYVGVIVDREIETIASILAVLKIGAAYIPINPEFPKERQTYIAKDGNCKVVLTAELAK
                     TIVASYKESKRESVAVPEQIAYAIYTSGSTGKPKGVIIKNEAVTNTILDINEKYSVNET
                     DRFIGLSSMSFDLSIYDIFGAFSAGATLVMIEDQRDIKKIHDIVKEEKITVWNSVPMIM
                     EMLVNYMDETENKSNAGVINYDELPELRLVLLSGDWIPVHLPERIKDHFVESEVISLGG
                     ATEASIWSIYYPIKTVKAEWTSIPYGYPLSNQTYYVLNYENDPCPIGVKGELYIGGKGV
                     AEGYLNDKEKTEASFIDHPDFGRIYRTGDMGVLTQEGYIEFLGRKDHQIKVRGYRVELG
                     EIESVILEHRQVRNAVVINQKDARNQDVLYA"
     CDS_motif       complement(86..151)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0015"
                     /evalue="1.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg62_1"
                     /protein_end="992"
                     /protein_start="970"
                     /score="39.0"
                     /tool="antismash"
                     /translation="FLGRKDHQIKVRGYRVELGEIE"
     aSDomain        complement(116..1288)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg62_1_AMP-binding.1"
                     /evalue="2.30E-98"
                     /label="ctg62_1_AMP-binding.1"
                     /locus_tag="ctg62_1"
                     /protein_end="982"
                     /protein_start="591"
                     /score="321.3"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="FARQTVKTPENVAIECQGRAVTYQELQGMSNRISSFLEEKGIQPN
                     EYVGVIVDREIETIASILAVLKIGAAYIPINPEFPKERQTYIAKDGNCKVVLTAELAKT
                     IVASYKESKRESVAVPEQIAYAIYTSGSTGKPKGVIIKNEAVTNTILDINEKYSVNETD
                     RFIGLSSMSFDLSIYDIFGAFSAGATLVMIEDQRDIKKIHDIVKEEKITVWNSVPMIME
                     MLVNYMDETENKSNAGVINYDELPELRLVLLSGDWIPVHLPERIKDHFVESEVISLGGA
                     TEASIWSIYYPIKTVKAEWTSIPYGYPLSNQTYYVLNYENDPCPIGVKGELYIGGKGVA
                     EGYLNDKEKTEASFIDHPDFGRIYRTGDMGVLTQEGYIEFLGRKDHQIKVR"
     aSModule        complement(116..2662)
                     /domains="nrpspksdomains_ctg62_1_Heterocyclization.1"
                     /domains="nrpspksdomains_ctg62_1_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg62_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(227..316)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0014"
                     /evalue="7.90E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg62_1"
                     /protein_end="945"
                     /protein_start="915"
                     /score="43.8"
                     /tool="antismash"
                     /translation="PIGVKGELYIGGKGVAEGYLNDKEKTEASF"
     CDS_motif       complement(710..745)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0013"
                     /evalue="4.70E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg62_1"
                     /protein_end="784"
                     /protein_start="772"
                     /score="-1.4"
                     /tool="antismash"
                     /translation="GAFSAGATLVMI"
     CDS_motif       complement(863..919)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0012"
                     /evalue="9.50E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg62_1"
                     /protein_end="733"
                     /protein_start="714"
                     /score="27.4"
                     /tool="antismash"
                     /translation="AYAIYTSGSTGKPKGVIIK"
     CDS_motif       complement(1064..1102)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0011"
                     /evalue="6.20E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg62_1"
                     /protein_end="666"
                     /protein_start="653"
                     /score="13.2"
                     /tool="antismash"
                     /translation="LAVLKIGAAYIPI"
     CDS_motif       complement(1244..1297)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0010"
                     /evalue="5.00E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg62_1"
                     /protein_end="606"
                     /protein_start="588"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="YHLFARQTVKTPENVAIE"
     CDS_motif       complement(1469..1543)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0009"
                     /evalue="2.20E-05"
                     /label="Cy7"
                     /locus_tag="ctg62_1"
                     /protein_end="531"
                     /protein_start="506"
                     /score="17.4"
                     /tool="antismash"
                     /translation="ISQTSQVYLDHQVIELNDGVMLSWD"
     CDS_motif       complement(1607..1633)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0008"
                     /evalue="5.70E-03"
                     /label="Cy6"
                     /locus_tag="ctg62_1"
                     /protein_end="485"
                     /protein_start="476"
                     /score="9.6"
                     /tool="antismash"
                     /translation="MPVVFTSML"
     CDS_motif       complement(1673..1717)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0007"
                     /evalue="1.30E-04"
                     /label="afterCy5"
                     /locus_tag="ctg62_1"
                     /protein_end="463"
                     /protein_start="448"
                     /score="14.8"
                     /tool="antismash"
                     /translation="ALEHRDYDGVEFIRE"
     aSDomain        complement(1778..2662)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg62_1_Heterocyclization.1"
                     /evalue="7.60E-90"
                     /label="ctg62_1_Heterocyclization.1"
                     /locus_tag="ctg62_1"
                     /protein_end="428"
                     /protein_start="133"
                     /score="293.2"
                     /tool="antismash"
                     /translation="TEFDLTNVQMAYLMGRDKQFELGGTSTHAYLEIETELNIEKLNKS
                     LQKVIDYQDMLRAVVLPNGRQKILQQVPQYEISVQDISQLSDIEQEKKIVEERDRTSHR
                     IFNPNEWPLFEFKALKIQGDKHRLFFGIDMLIADGASIQLLFKQISEFYNGKDEMVPLE
                     ISYRDYMLAYQKVKTTHKYENDKAYWLSQLEDFPKAPAVPLKERLDAISKPTFNRKSKI
                     IDKPLWETFCKKAASYNITPAIILFTAYAKVLSKWSNQQNLAVNTTVFNRQPFHKQVND
                     IIGDFTSLIMLKAS"
     CDS_motif       complement(1787..1837)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0006"
                     /evalue="6.20E-07"
                     /label="Cy5"
                     /locus_tag="ctg62_1"
                     /protein_end="425"
                     /protein_start="408"
                     /score="21.7"
                     /tool="antismash"
                     /translation="HKQVNDIIGDFTSLIML"
     CDS_motif       complement(1838..1873)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0005"
                     /evalue="5.70E-03"
                     /label="afterCy4"
                     /locus_tag="ctg62_1"
                     /protein_end="408"
                     /protein_start="396"
                     /score="9.6"
                     /tool="antismash"
                     /translation="AVNTTVFNRQPF"
     CDS_motif       complement(1889..1948)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0004"
                     /evalue="2.30E-05"
                     /label="Cy4"
                     /locus_tag="ctg62_1"
                     /protein_end="391"
                     /protein_start="371"
                     /score="17.3"
                     /tool="antismash"
                     /translation="NITPAIILFTAYAKVLSKWS"
     CDS_motif       complement(2240..2284)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0003"
                     /evalue="9.00E-06"
                     /label="Cy3"
                     /locus_tag="ctg62_1"
                     /protein_end="274"
                     /protein_start="259"
                     /score="18.8"
                     /tool="antismash"
                     /translation="RLFFGIDMLIADGAS"
     CDS_motif       complement(2465..2503)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0002"
                     /evalue="1.30E-05"
                     /label="Cy2"
                     /locus_tag="ctg62_1"
                     /protein_end="199"
                     /protein_start="186"
                     /score="17.6"
                     /tool="antismash"
                     /translation="DMLRAVVLPNGRQ"
     CDS_motif       complement(2486..2581)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg62_1_0001"
                     /evalue="4.20E-04"
                     /label="C2_dual_024-063"
                     /locus_tag="ctg62_1"
                     /protein_end="192"
                     /protein_start="160"
                     /score="12.9"
                     /tool="antismash"
                     /translation="HAYLEIETELNIEKLNKSLQKVIDYQDMLRAV"
     aSDomain        complement(2729..2932)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg62_1_PCP.1"
                     /evalue="1.80E-19"
                     /label="ctg62_1_PCP.1"
                     /locus_tag="ctg62_1"
                     /protein_end="111"
                     /protein_start="43"
                     /score="61.6"
                     /tool="antismash"
                     /translation="ERDLVDIWKSVLKTDEISIDDNFFELGGNSILIINLITAIEDRLF
                     IKLDFKNFISNSTIEKLAKVISV"
ORIGIN
        1 acgcatataa cacatcttga tttctggcat ccttttgatt aatgactacc gcgtttctca
       61 cctgtcggtg ctctaatatt acactttcta tttcacctaa ctccacgcga tatccacgaa
      121 ctttaatctg atgatctttc cgtcccaaaa actcaatata accctcttgc gtcaagaccc
      181 ccatatcccc cgtacggtaa attcttccga aatctgggtg atcaataaat gaagcttcag
      241 ttttttcttt atcatttaaa tagccttctg ctacgccttt tcctcctatg taaagttcac
      301 ctttaactcc gattggacaa ggatcatttt catagtttaa aacatagtaa gtttgatttg
      361 ataatggata accgtaagga atgctggtcc attcagcctt gactgtttta attggataat
      421 aaatcgacca aattgacgct tcagtagccc cgcctaagct tatgacttca ctttcaacga
      481 agtgatcctt aatcctctca ggaagatgaa caggtatcca atccccgctt aataatacca
      541 gtcttaattc aggaagctcg tcatagttaa taactccagc gttagatttg ttttctgttt
      601 catccatgta gtttactaac atttccatga tcatgggaac ggagttccag actgtaattt
      661 tttcctcttt tacgatgtca tgaatctttt taatatctct ctgatcttcg atcattacta
      721 atgttgctcc tgcagaaaaa gcaccaaaaa tatcatatat tgataaatca aaggacatag
      781 atgataatcc gataaaccgg tctgtttcat tcacactgta tttttcattg atgtctaata
      841 ttgtattagt tactgcctca ttctttatga ttacaccttt aggttttccc gtacttcctg
      901 aagtgtatat cgcataagct atttgttccg gcactgccac actttctctt ttagactctt
      961 tatagcttgc cacaatagtt tttgccagtt cagctgttaa tacaacttta caatttccat
     1021 ctttcgcaat atatgtttgt ctttcttttg ggaattccgg attaattggg atataggcag
     1081 ctccaatttt taacactgcg aggatactgg cgattgtctc gatctcacga tcaacaataa
     1141 ccccaacata ctcatttggc tgaattccct tctcttccaa aaaactagat atgcggttgg
     1201 acatgccctg taactcttga taggtaactg ctcttccttg acactcaatc gcaacattct
     1261 caggtgtttt tactgtttgt ctggcaaaca agtgatataa agtatccggc ttgatggcct
     1321 tctcagtttg attataatca gtaattgctt gttccagtgc tgtgtctcca gaagacatct
     1381 tctcaccgga cgttaattgg tcaataatgt gggtatattc ctcaaacatt gactcaatta
     1441 cgtcattttc aaaagcctct gaaacatagt cccagctaag catgactcca tcattgagct
     1501 ctatcacttg atgatccaga taaacttgtg atgtctgact gattgccatt tttaactcac
     1561 caatatttaa tagatcatta ttattaagat taaacatgtt tccaaataac atactggtga
     1621 acactactgg cattgtcgca cttttgtgat ttagattatt atatttagca tattctctta
     1681 taaattcaac tccatcatag tctctatgtt caagtgcttc catgaaagta acctgaacct
     1741 tttttgcctc ctcccaaaag ttcatttttt tctcaaaact cgcttttaac ataatcagcg
     1801 atgtaaaatc acctattata tcattaactt gtttatggaa aggctgtcta ttaaatactg
     1861 ttgtatttac cgctaagttt tgttggttac tccacttcga caacactttt gcgtaggctg
     1921 taaataatat tattgcaggt gtaatattat agcttgcagc ttttttacaa aatgtttccc
     1981 atagaggctt gtcaattatt ttagattttc tattgaaagt tggcttgctt attgcatcta
     2041 atctttcttt taatggcacc gcaggtgctt ttggaaaatc ttcgagctga cttaaccaat
     2101 aggctttatc attttcatat ttgtgagtgg tcttgacttt ttggtatgct aacatataat
     2161 ctctatagct tatttccaat ggcaccattt catcttttcc attataaaat tcagatatct
     2221 gtttaaataa aagctggata ctggcaccat cagctattaa catatcgata ccgaaaaata
     2281 atctatgttt atccccttga attttcaagg ctttgaattc aaataaaggc cactcatttg
     2341 gattaaagat acgatgtgat gttctgtctc tttcttctac tattttcttc tcttgttcta
     2401 tatcacttaa ttgactaata tcctgtacag atatttcata ctgagggact tgttggagaa
     2461 tcttttgcct tccattcgga agaacgaccg cacgcagcat gtcttgataa tctattactt
     2521 tttgtaaact tttgttgagt ttttcaatgt tcagctcagt ctcaatttct aaataagcat
     2581 gcgtggaagt gccaccaagt tcaaattgtt tatctctccc cataagataa gccatttgaa
     2641 cgttagttaa atcgaattct gtatttttat tcttaatatc agcttggatt tccatcacat
     2701 tactatttgt tttacttttt ctttcagaaa cactgattac ttttgctagt ttctcaatgg
     2761 tactgttgga tataaaattt ttaaaatcta atttaataaa taaacgatcc tcaatagcag
     2821 taattaaatt aatgatcaat atggaattgc cgcctaattc aaaaaagttg tcatctatgc
     2881 tgatttcatc tgttttcaga acgcttttcc agatatcaac taaatctctc tcaatttctg
     2941 ttcgaggttc tttgattttc cttccaatcg atgcttgatc tgtaacgtct aaagccagca
     3001 gttttttacg atcaactttt ccgttacttg ttaaaggaac ttcttcaatc tgtacgatat
     3061 ag
//
