LOCUS       c00031_gnlPro..        10968 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IABDAINK_31.
ACCESSION   c00031_gnlPro..
VERSION     c00031_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 18:19:02
            Original ID  :: gnl|Prokka|IABDAINK_31
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10968
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10968
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:5232]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..5232
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..10968
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10968
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             2..589
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_1"
                     /sec_met_domain="HBT (E-value: 6.4e-19, bitscore: 57.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="IVIGDGVCDVSMIQFAGLGIAMGNAQDSVKVCADVVTASNEEDGV
                     ALAVEKAILSEIRPAEIPLDQLNERARHALMGNLGIQYTYASEDRVEATMPVDERTRQP
                     FGILHGGATLALAETVAGLGSMILCQPDEIVVGMQVSGNHMSSAHEGDTVRAVGTIIHK
                     GRSSHVWNVDVFTSTDKLVSSIRVVNSILKKR"
     CDS             586..1692
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_2"
                     /sec_met_domain="Chorismate_bind (E-value: 1e-54, bitscore:
                     175.2, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLEETNNCEIIDELIRQGRSFAMYRNPGEEEPHFLMQTCGEVHL
                     IRKMEDLNGRTGFVIAPFRVTPQCPIILIRPDCHEIPSCAGNLHTPAQGDDAASYGQQL
                     RSDRSLGAKKAYEACFDVFIRALRERTFDKLVLSRRMTVRREPGFSPAAAFYRACRRYI
                     YSYVYLCYTPQTGVWMGSTPEIILSGEKGEWNTVALAGTQSLQNGELPQQWDEKNREEQ
                     EYVAAYIRKQLRSLGISPTEKGPYPAFAGALSHLKTDFHFSLNDSQRLGDLLKLLHPTP
                     AVCGLPKEEAYRFILDNEGYDRSYYSGFIGWLRPEGRTDLYVNLRCMNVKEDSLTLYAG
                     GGLLASSELDDEFQETEKKMQTMQNLNS"
     CDS             1713..3380
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.8e-08, bitscore:
                     23.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLRAHGVTKVVLCPGSRNAPIVHTLAGHPDFT
                     CYSVTDERSAGFFAIGLALQGGTPAAVCCTSGTALLNLHPAIAEAYYQKVSLVVISADR
                     PAAWINQMDGQTLPQPGVFRSLVKKSVDLPEIHTDEDEWYCNRLLNEALLELNHHGKGP
                     VHINVPVSEPLFQFTAESLPEVRVITRYQGLNVYDRDYDGLIDRLNKYNRRMMIVGQMN
                     LIYLFEKKYSKMLYKQFAWFTEHLGNQTVPGIPIRNFDAALYAMSPEMQEKMIPELVIT
                     YGGHIVSKRMKKYLRQHPPKEHWHVSPDGEVIDLFQGALTTIIEMDPFEFMEKIAFLLD
                     NRTPEYPRQWENFCKELPRPELPYSEMSAIGSLIQALPASCALHLANSSAVRYAQLYSL
                     PDTVEVCCNRGTSGIEGSLSTAIGYAAASKKLNFVVIGDLSFFYDMNALWNNHFGSNLR
                     ILLLNNGGGEIFHTLPGLEMSGTSHRFVTAVHKTSAKGWAEERGFLYQEVQDEKQLDEA
                     MKTFTQPELLTQPVIMEVFTNKNKDARILKDYYHQLKN"
     CDS             3382..4386
                     /locus_tag="ctg31_4"
                     /transl_table=11
                     /translation="MMTKHKMNLFCGMLLLSASLFVEKAQAMFPERYVSEESAARADTI
                     NFRLASAGEAKRLIAAKDSYTANWSPFDIAARLENPEGKREDLVSLAVREVREWTAEEA
                     QQIEQIRKNLNDTIRKYGYRIPFPKEIVLVKTTMKDEGGAGGYTRSNWIALTDATFQRG
                     TEASHTRLLVHETFHILTRLNPGFKKKLYRAIDFNILPKEIEFPEDIRKSRISNPDVSR
                     CDSYATFTIDGKPQNCTMIIYTNRPYTTGKFYQYINVGLIPLDESFKPLRESGKTVIYP
                     LQKATDFFDKVGRNTGYVIDPEEVLADNFAIALLNTPNVHTPELQKKVQELLK"
     CDS             4408..5232
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_5"
                     /sec_met_domain="ECH_1 (E-value: 6.2e-83, bitscore: 267.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METKREWTPIKEYEDILFDYYNGIARITINRERYRNAFTPTTTGE
                     MSDAMCICREEPDINVVVLTGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGSSYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLDKLEDEYVQWAEEMMQLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPDFKQYPKFP"
     CDS             5281..6300
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_6"
                     /sec_met_domain="MR_MLE_C (E-value: 9.4e-31, bitscore:
                     96.5, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTINIIPRVLHFKQPAGTSRGSYTTRNVWYIHLSSIECPGRVGV
                     GECAPLPKLSCDDLPDYEQVLRSACQRLEQTGELDIESLRGYPSILFGLETALRHYETQ
                     SWALWDTPFSRGEAGIPINGLIWMGSFDRMLQQIEVKMQAGYRCIKLKIGAINFEEELA
                     LLRHIRAHYSAREIELRVDANGAFSPADAMDKLNRLAELDLHSIEQPIRAGQWEEMARL
                     AAESPLPIALDEELIGCNALERKRELLAAIHPRYIILKPSLHGGISGGNEWIAEAEKQH
                     IGWWITSALESNIGLNAIAQWCATFRNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFCK"
     CDS             6314..7408
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 60.5; E-value:
                     3.6e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_7"
                     /sec_met_domain="AMP-binding (E-value: 5.9e-20, bitscore:
                     60.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFNREEQHLMLEGSVLSKEDVKRLVACYTEEASGFLYELYRFLE
                     EWFSDSPYLTVKTSGSTGTPKLLKVRKEQMMQSARLTCEFLGLRQGDSVLLCMPLQYIA
                     GKMVVVRALVAGLNLVIRTPSGHPMADVDIPLRFAAMVPLQVYNTLQVSAEKEKLCRTD
                     ILIIGGGAIDAGLEAEIRQLPVKVYSTYGMTETLSHIALRQLNGPDASMLYRPFPSVRL
                     SLSSEHTLVIDAPLVCDTTLVTNDVAEIYSDGSFSILGRKDNTINTGGIKVQAEQIEEI
                     LRPWMRVPFAITSVPDARLGEAVVLLVEKGADAELPETKMKELLSKYQLPKMILSVGAI
                     PLTETGKINRAACRQLVLTYRTDR"
     CDS             7479..8336
                     /locus_tag="ctg31_8"
                     /transl_table=11
                     /translation="MNKICFFIGVFITLLLAGCSSNPISHVRVATFNIRYDNLGDSLNS
                     WKYRKEKVCEFIREKHPDVLGMQEVLNHQLKDLLSGLPDYAYVGVGREDGKTQGEYAPV
                     FYRKDKYDLLDSNTFWLSEHPDSIGKLGWDAACTRVATWAKLKDKTTGKEFLMLNTHFD
                     HVGTEARRNSALLIIDKIKEIAGTHPAMMTGDFNVSEEWEAYKTITSNEFVLKDAWKIA
                     GKQSGENYTFHDFGRVPVAEREKIDFIFVTPQIKVADAEIISSAITDSTYLSDHNAHLA
                     DLEF"
     CDS             8359..10374
                     /locus_tag="ctg31_9"
                     /transl_table=11
                     /translation="MKQILHILLIALMLMGFYSCVPKTELASPDGHIKVAFTADTDGKM
                     MYRVTVNDTLLLDNSPLGFEAKDGIDLNRGFRVVSTVFTDKDEIWTQPWGENKTNRNHY
                     NEMAVLLKNAANVELTLRFRAFDDGVAFRYEYEVPGVDSLLITDELTAFRFHEDGTSWS
                     IPASFETYELLYSKQKISEVENANTPFTFKTSGGVYGSIHEAALYDFPEMTLKKDGKNT
                     LKSELASWPDGIKARKENRFTTAWRTIQIAPQAVGLINSSLILNLNEPCKLDTTDWIKP
                     MKYVGVWWGMHLGVETWKMDDRHGATTANAKKYIDFAHANNIEGVLFEGWNEGWESWGG
                     MQSFDFTKPYADFDMDEITRYAREKNVQIIGHHETGGNIPNYERQMEKAIKWYTDKGIH
                     ILKTGYAGAFPDGHSHHGQYGVNHYQKVVETAARYRMTLDAHEPIKDTGIRRTWPNMMT
                     REGARGMEWNAWSEGNPPSHHEMLPFTRLLGGPMDYTPGTFDILFTQTKDSPKRQKWND
                     QDKGNSRVNTTLAKQLANWVILYSPLQMASDMIEHYKGHPAFRFFRDFDPDCDESRALA
                     GEPGEFVAVVRKAKQNYFLGASTNEEPRVLPVSLDFLEKGKTYKAIIYADGEKADWKTN
                     PTEYQITEQEVTADDTLNIRMAAGGGQAISFMPLQK"
     CDS             complement(10351..10950)
                     /locus_tag="ctg31_10"
                     /transl_table=11
                     /translation="MAQTLTNLNINDNNAVISALREGDEEVFDHIYRYYFRGLCAFCSQ
                     YVTLSESEEIVQDTMMWLWENRKTLIPELTLKTLLFTIVKNKALNKISHFEIKRKVHQE
                     IAEKYETEFSSPDFYLENELFRLYEEALRKLPAEFRQAYEMNRSLQMTHKEIAEKLNVS
                     PQTINYRIGQALKILRSELKDYLPLIMLFLFLQGHK"
ORIGIN
        1 cattgttatc ggtgatggcg tttgcgatgt ttccatgatc cagtttgccg gattgggtat
       61 cgccatgggc aatgctcagg attcggtaaa ggtatgtgcc gatgtggtga cggcttcgaa
      121 tgaagaagac ggagttgctc ttgccgtaga aaaagcgatt ctttctgaga ttcgtccggc
      181 agagattcct ctcgaccaat tgaacgagcg tgcacgtcat gccttgatgg gaaatctggg
      241 cattcaatat acctatgctt ccgaagaccg ggtagaggct actatgccgg tagacgagcg
      301 gacccgtcag cctttcggca ttctgcacgg aggtgccacg ttggcactgg ccgagactgt
      361 tgccggactg ggttcgatga ttctctgcca gcccgacgag attgtggttg gtatgcaggt
      421 cagcggtaac cacatgtcat ctgcccacga gggagatacc gtacgtgccg tcggtaccat
      481 tatccacaaa ggacgttcat cacatgtctg gaatgtagac gtatttacgt cgacggacaa
      541 gttggtgtct tccatacggg tagtgaatag tatattaaag aagagatgac gttagaagaa
      601 acaaataatt gtgagattat agatgaattg atccgtcagg gaaggagctt cgcaatgtat
      661 cgtaatccgg gcgaagagga acctcacttt ctgatgcaga cttgcggaga agtacacctt
      721 atccggaaaa tggaagattt gaatggtcgg acaggctttg tcatcgcccc tttccgggtc
      781 actccgcaat gtcctatcat attgatccgg ccggattgtc atgagattcc ttcctgcgcc
      841 ggaaacttgc atacccctgc acagggggac gatgcggcat cgtacgggca acagctccga
      901 agcgaccggt cactcggggc gaagaaagcc tatgaggctt gtttcgatgt ctttatcagg
      961 gctttgaggg aacgtacttt tgataagttg gtactatccc gcagaatgac ggtgaggaga
     1021 gagccgggat tctctcccgc agcggctttc taccgggctt gcaggcgtta catctattcg
     1081 tatgtctatc tttgctatac tccgcaaacc ggggtgtgga tgggcagtac tccggaaatc
     1141 attttatcgg gtgagaaagg agaatggaat acggtagcgt tggcaggaac ccagtcttta
     1201 cagaatggtg agcttccgca acaatgggat gaaaagaacc gggaggagca ggagtatgtg
     1261 gcggcatata ttcgtaaaca actccgctcg ttggggattt ctccgacaga gaaaggacct
     1321 tatccggctt ttgccggggc attgtctcac ctgaaaacgg atttccactt ctcgctgaac
     1381 gacagtcaga ggttgggaga tttattgaag ctgttgcatc ccactcccgc cgtatgcgga
     1441 ttgccaaaag aagaagctta ccggtttatc cttgacaatg aaggctatga ccgcagctat
     1501 tattccggat ttataggctg gttgaggccg gaagggagaa cggacctgta tgtcaactta
     1561 cgctgtatga atgtgaaaga agattcgttg acattgtatg ccggaggcgg cctgctggcc
     1621 tcttccgaat tggatgatga gtttcaggag acggaaaaga agatgcagac catgcagaac
     1681 ttgaactcct aaataaaata atatataaag cgatgtattc agataagaaa aacatattgc
     1741 agttggtagc gttgctccgt gcacatgggg tgacgaaagt cgttttatgt cccggaagcc
     1801 ggaatgcacc gattgtacat acacttgccg gacatcccga cttcacttgt tactcggtaa
     1861 cagacgagcg gagtgccggc ttttttgcta tcgggcttgc tttgcagggc ggaactcctg
     1921 ccgctgtttg ttgcacatcg ggcacggctt tgttgaattt gcatcctgcc atagcagagg
     1981 cctactacca gaaagtatct ttagtagtta tttccgccga tcgtcctgcc gcctggatca
     2041 accagatgga cggacagact ttacctcagc cgggtgtttt ccggtcattg gtgaagaagt
     2101 ctgtcgatct gcccgaaata catacggacg aggatgaatg gtactgcaac cgcttgctga
     2161 acgaagcatt gcttgaactg aatcatcatg gtaaaggccc tgtgcacatc aacgtgccgg
     2221 tttccgaacc cctgttccag tttacggcag agtcacttcc cgaagtacgt gtcatcacac
     2281 gttatcaagg actgaatgtt tatgatcgcg actatgacgg cttgatcgac cgcctcaata
     2341 aatacaaccg ccgtatgatg atcgtcggcc agatgaacct gatttatctg ttcgaaaaga
     2401 aatattcaaa gatgctctac aagcagtttg cctggttcac ggagcattta ggcaatcaga
     2461 ccgttccggg catcccgatc cggaacttcg atgcagccct ctatgccatg tcacccgaga
     2521 tgcaagagaa gatgattccc gaattggtga tcacttacgg ggggcatatc gtctctaaac
     2581 gaatgaaaaa gtatcttcgc cagcatccgc ccaaagagca ttggcatgtg tcgccggatg
     2641 gtgaagtgat cgatctgttc caaggggcat tgactacgat tatcgagatg gacccatttg
     2701 aatttatgga gaagatagct tttctgctgg ataaccgtac accggaatat ccccggcaat
     2761 gggagaactt ctgcaaggag cttccccgac cggagttgcc ttattccgaa atgtctgcta
     2821 tcggatcact cattcaggcg ttgcctgctt cgtgtgcttt gcatctggcc aatagttccg
     2881 ccgtgcgtta tgcccagctt tattcgcttc ccgatacggt agaggtttgt tgcaaccggg
     2941 gtacgagcgg cattgaaggt tccctttcca cagcgatcgg ttatgctgcc gcttcgaaga
     3001 agttgaactt tgtggtcatt ggtgatctga gctttttcta tgatatgaat gccctgtgga
     3061 acaatcattt tggaagtaac ctccgtattc tgcttttgaa taatggggga ggggagattt
     3121 ttcatacttt gccgggactt gaaatgtccg gtacttccca tcgctttgtg actgccgtgc
     3181 ataagacgtc tgccaaggga tgggccgaag aacggggatt cctctatcag gaagtgcagg
     3241 atgaaaaaca gttggacgaa gccatgaaaa ctttcactca acccgagtta ctgactcaac
     3301 ctgtcattat ggaggttttc accaataaaa ataaagatgc acggatattg aaagactact
     3361 atcaccaact aaaaaactaa tatgatgact aagcacaaga tgaacctatt ttgtgggatg
     3421 ctacttttgt cagcttccct gtttgtggag aaagctcaag ccatgtttcc cgagagatac
     3481 gtatcggagg aatcggcagc cagggcagat acaatcaatt ttcggttggc ttctgccgga
     3541 gaagcaaaac gcctgatagc ggccaaagat tcttatacgg ctaattggag tccgtttgac
     3601 atcgctgccc gacttgaaaa tcctgaaggc aaaagagaag acctcgtcag cctggccgtt
     3661 cgtgaagtgc gtgaatggac agcggaagaa gcgcagcaga tcgagcagat caggaagaac
     3721 ctgaatgata cgattcgtaa atacggctat cggattccat ttccgaaaga gattgtgctg
     3781 gtaaagacaa caatgaaaga cgaaggaggg gcgggaggat acacacgcag taactggatc
     3841 gcattgacgg acgctacttt tcagcggggg accgaagctt ctcacacacg cctgctggtg
     3901 catgaaactt tccacatcct gacacgtctc aatcccggat tcaaaaagaa actgtacaga
     3961 gctatcgact tcaacatcct gcccaaagag attgagttcc ccgaagatat acggaaaagc
     4021 cgtatctcca atcccgatgt cagtcgttgc gatagttatg cgacttttac cattgacggt
     4081 aagccacaga actgcactat gattatctat accaacagac cctataccac gggtaagttc
     4141 tatcagtata tcaatgtggg gctgattccg ttggacgagt cgttcaagcc tctccgggag
     4201 agtgggaaga cagtgattta tccattacag aaagcgaccg acttctttga taaagtaggg
     4261 cggaacaccg gatatgtcat agatccggaa gaggtgctgg cggataattt tgcaattgct
     4321 ttattgaaca cgcccaatgt acatacaccc gaactgcaaa agaaagtaca ggaattactg
     4381 aaataataat catcaaaata aatagaaatg gaaactaaaa gagaatggac tcctattaaa
     4441 gaatacgaag atattctgtt tgattactat aacggcattg cccgtattac gatcaatcgc
     4501 gaacgttacc ggaatgcttt cacccctact acaacaggcg aaatgagcga tgcgatgtgc
     4561 atctgtcgtg aagagcccga tatcaatgtt gtggtattga ccggtgcagg cgataaggcc
     4621 ttctgttcgg gaggcgacca gaacgtaaag ggccgtggcg gatacatcgg taaagacgga
     4681 gtgccccgcc tgagtgtact ggatgtgcaa aaacaaatcc gttcgattcc gaaaccggtt
     4741 attgctgccg ttaacggatt tgccatcgga ggcggacacg tgttgcatgt cgtatgcgat
     4801 ctctctattg cttccgaaaa tgccatcttc ggacagacag gtcctcgtgt aggtagtttc
     4861 gatgccggct tcggatcatc ttatcttgcc cgcgttgtgg ggcagaagaa ggcccgtgag
     4921 atctggttcc tttgtcgcaa gtataatgcg caggaggctc tggatatggg gctggtcaat
     4981 aaagtggtac cgctggataa actggaagac gagtatgttc agtgggcgga ggagatgatg
     5041 cagcttagtc cgttggcact ccgcatgatt aaagccggtc tgaatgccga actcgacggt
     5101 caagccggta ttcaggaact ggcaggtgat gccactctgc tttattacct taccgatgaa
     5161 gcacaggaag gcaagaatgc ttttctggag aagcgtaaac cggactttaa acaatatcct
     5221 aaatttccat aagcagacag gggccttctt gatgggaggc cttttcttta tatcattttt
     5281 atgtatacaa tcaacattat tccacgcgtt cttcatttca agcaacctgc gggaacttcg
     5341 cgtggttctt atactacccg gaatgtctgg tatatccatc tttcttccat agagtgtccg
     5401 ggacgtgtcg gagtaggaga gtgtgctccg ttacccaaac tgagttgtga tgacttgccg
     5461 gattatgaac aggtgcttcg gagtgcctgt cagcgactgg aacaaacggg agaactggat
     5521 atagaatctt tacgtgggta tccttctatt ctgttcggac tcgagacagc actgcgccat
     5581 tacgaaacac agagctgggc attatgggat actccttttt cgcgcggaga agccggtata
     5641 cctattaacg gacttatctg gatggggagt tttgacagaa tgctgcaaca gatcgaagtc
     5701 aagatgcagg cgggatatcg ctgtatcaaa ctaaaaatcg gtgcgataaa ctttgaagaa
     5761 gaattagccc tgttgagaca tatccgtgct cactattccg ccagagaaat agagttgaga
     5821 gtggatgcca atggagcttt ctcacctgcc gatgctatgg ataaactgaa tcggttggcc
     5881 gaattggacc tacattccat agagcagcct atccgggccg ggcagtggga ggaaatggcc
     5941 cgtctggcgg ctgagtcccc gcttcctatt gctttggacg aagaactgat aggttgcaat
     6001 gcccttgaaa gaaaacggga attgctggcg gctatccacc cccggtatat catactgaaa
     6061 ccatctctgc atggcgggat cagtggtggc aacgaatgga ttgcagaagc ggaaaagcaa
     6121 catatcggtt ggtggatcac atctgcgctg gagtcgaata tcggtctgaa tgccatagcc
     6181 caatggtgtg cgactttccg gaatccgttg ccacaaggat taggtaccgg gctactgttt
     6241 acggacaatg tcgagatgcc cctcgagatt cgaaaagatt gtttatggtt ttgcaaataa
     6301 gaggagtcgg cacatgatat ttaatagaga agaacaacac ctaatgttgg aaggcagtgt
     6361 gctttccaag gaggacgtga aaaggctggt ggcttgttac acggaggagg catcgggatt
     6421 tttgtacgaa ctttaccggt ttctggaaga gtggttcagt gattctcctt atctgacagt
     6481 gaaaacttcc ggttctaccg ggactcccaa actgctgaag gtccgtaagg agcagatgat
     6541 gcaaagtgcc cgactgactt gtgagtttct gggacttcga caaggagata gcgtattgtt
     6601 gtgtatgcct ttgcaatata ttgccgggaa gatggtggtg gtccgggcat tggtggcagg
     6661 gttgaatctg gttatccgga ctccttccgg gcatccgatg gcggacgtgg acataccgct
     6721 tcgctttgcc gctatggtgc cgttgcaggt ttacaacaca ctgcaggtat cggcagaaaa
     6781 agagaagctc tgccggaccg atattcttat tataggcgga ggggcaatag atgcagggtt
     6841 ggaagctgag atacggcaat taccggttaa ggtttattct acgtatggca tgacagaaac
     6901 cctttcacat attgctttaa gacagttgaa cggaccggat gcgagtatgt tgtaccggcc
     6961 ttttccttcg gtgcggcttt ctctttcgtc cgaacataca ttggtgatcg atgctccatt
     7021 ggtttgtgat accactttgg tgacaaatga tgttgcggag atctattccg atggcagctt
     7081 ctctattttg ggcaggaagg ataataccat caataccgga ggtatcaaag tacaggcaga
     7141 gcagatagaa gagatacttc gtccctggat gagagttcct tttgcaatca cttctgtacc
     7201 cgatgccaga ttaggagagg cggttgtgct tttggtagag aagggggcag atgcagagtt
     7261 accggaaaca aagatgaagg agcttctgtc taaatatcag ttacccaaga tgattttgtc
     7321 agtcggggct atacccttga cggaaacggg aaagatcaat cgtgccgctt gccggcaact
     7381 tgtcctcact tatcggacag atcgctaagt gttttttctt ctttagttgt atcatatacg
     7441 aaatagcttt aaatttaata accaacacat ataaactaat gaataagatt tgctttttta
     7501 tcggagtttt tattaccctg cttttggcgg gttgcagttc taatccgatt tcccatgttc
     7561 gtgtggcgac ctttaatatc cgctatgata atctgggcga cagtttgaat tcctggaagt
     7621 atcgtaaaga gaaggtctgt gaatttatcc gtgagaaaca tcccgatgtg ctgggaatgc
     7681 aggaagtact gaatcatcag ttgaaagacc tgttgtccgg cctgcctgat tatgcctatg
     7741 taggtgtggg acgcgaggat ggaaagactc agggggaata tgctcctgta ttctatcgga
     7801 aagataaata tgatttgtta gacagtaata cattctggct ttccgaacat ccggatagta
     7861 tcggcaaact tggttgggat gccgcgtgta cccgcgtggc tacttgggct aaattaaagg
     7921 ataaaactac cggaaaagag tttctgatgt taaacaccca ttttgaccac gttggtacgg
     7981 aagctcgtcg taacagtgcc ctgcttatta ttgataagat aaaagaaata gccggtacgc
     8041 atcctgctat gatgaccgga gactttaatg tttctgaaga gtgggaagct tacaaaacga
     8101 tcacatccaa tgagtttgtc ttgaaagatg catggaagat agccgggaaa cagtccggtg
     8161 agaactacac tttccatgat ttcggaagag tacctgtggc cgaacgggaa aagatcgatt
     8221 tcattttcgt aactccgcaa atcaaggtgg cagatgcaga gattatttct tctgcgatta
     8281 cagattccac ctatttgtcc gatcataatg cacatctggc tgatttggaa ttctaaaccg
     8341 tataaacgaa ttgtaaccat gaaacagatt ttgcatatat tactcatcgc cttgatgctg
     8401 atgggctttt atagttgtgt tccgaagacg gaattagcct ctccggacgg acatatcaaa
     8461 gtggctttta ctgcggatac cgatggaaag atgatgtatc gggtgactgt caacgatacc
     8521 cttttattgg ataactctcc gctcggtttc gaagcgaaag acggaatcga tcttaatcgg
     8581 ggatttcgtg tggtgagcac tgtctttacc gataaagacg agatctggac gcagccttgg
     8641 ggagagaata aaacgaaccg gaatcattat aatgaaatgg cggttcttct gaaaaatgcc
     8701 gctaatgtgg aattgactct tcgttttcgt gcatttgatg atggtgtagc ctttcgttac
     8761 gagtatgagg tgcccggtgt cgactctttg ttgatcaccg atgaactgac tgctttccgc
     8821 tttcatgaag acgggacctc ttggtctatt cctgccagtt tcgagactta tgaattgctg
     8881 tactcgaaac agaagatcag tgaagtggag aatgccaata ctcctttcac tttcaaaaca
     8941 tccggagggg tgtatggcag cattcatgaa gccgctcttt atgattttcc ggaaatgact
     9001 ttgaagaagg atggtaaaaa tactctgaaa tccgaacttg cctcatggcc cgatggaatt
     9061 aaagctcgta aagagaatcg ttttaccact gcatggcgta ccattcagat tgctccgcaa
     9121 gctgtcggac tgattaattc gtcgttgatc cttaacctga atgaaccttg taaactggat
     9181 accaccgact ggatcaagcc gatgaaatat gtcggtgtct ggtgggggat gcatctggga
     9241 gtggaaacct ggaagatgga cgatcggcat ggcgctacaa ccgccaatgc caagaaatac
     9301 attgattttg ctcatgccaa taacatcgaa ggtgtgttgt ttgaggggtg gaatgaagga
     9361 tgggaaagtt ggggaggtat gcagagtttt gactttacta aaccttatgc cgactttgat
     9421 atggatgaaa taactcgtta tgcacgtgaa aagaatgttc agatcatcgg acatcatgaa
     9481 accggtggaa acattcccaa ctacgagcgc cagatggaga aggcaatcaa gtggtatacc
     9541 gataagggca ttcatattct gaaaacaggt tatgccggtg cttttcctga cggacattca
     9601 catcatggac aatatggagt gaaccattat caaaaagtgg ttgagacggc tgcccgttat
     9661 cgtatgactc ttgatgcgca cgaacctatc aaagataccg gtatacgacg tacctggccc
     9721 aatatgatga cacgtgaagg cgctcgcggt atggagtgga atgcctggag cgagggtaat
     9781 cctccttcac atcatgaaat gttgccgttt acccgcttat tgggtggtcc gatggactat
     9841 actccgggta cttttgatat tttgtttaca cagacgaaag attctcctaa acgtcagaag
     9901 tggaatgatc aggataaggg caatagtcgc gtcaatacaa cattggccaa gcagttggct
     9961 aattgggtga ttttatattc tccgttacaa atggcatctg atatgatcga gcactataaa
    10021 gggcatcctg ccttccggtt cttccgtgat ttcgatcctg attgtgacga atcgagggca
    10081 ttggccggtg agccgggaga gtttgtagca gtggtacgga aggctaaaca gaattatttc
    10141 ctgggtgcct ctacgaatga agaaccgcgg gtcttgcctg tcagtcttga ttttttagag
    10201 aaggggaaga cctataaagc aatcatctat gctgatggtg agaaagctga ttggaaaacc
    10261 aatccgacag agtatcagat tacggaacag gaggtgactg cagacgatac gttgaatatc
    10321 cgtatggcag ccggtggcgg acaagctatt tcatttatgc ccttgcagaa ataaaaacaa
    10381 catgatcagc gggagataat cctttagttc ggaccgtaat attttcaggg cttgccctat
    10441 acgataattg attgtttgcg gagagacgtt cagtttctcc gcaatttctt tatgagtcat
    10501 ttgaagactt cgattcattt cgtatgcctg gcgaaattcg gccggtagtt ttcttaaagc
    10561 ctcttcgtac aatctgaata gttcgttttc caggtaaaag tcaggtgaag agaactccgt
    10621 ttcatatttt tccgcaattt cctgatgcac cttgcgtttt atttcaaaat gagagatttt
    10681 attaagcgct ttgttcttga cgatagtaaa gagaagagtc tttaaagtaa gttccggtat
    10741 aagggttttt ctgttttccc atagccacat catagtatcc tgcacgattt cttccgattc
    10801 gctcagagtg acatattgag agcaaaaagc gcataatcca cgaaaatagt aacggtagat
    10861 atgatcaaac acctcttcat ccccttctcg cagggctgat ataacggcat tattatcatt
    10921 tatgtttagg ttagtcagag tctgtgccat tcttctctcc attgttat
//
