LOCUS       c00063_gnlPro..        11340 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AKCPGBIB_63.
ACCESSION   c00063_gnlPro..
VERSION     c00063_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 18:33:57
            Original ID  :: gnl|Prokka|AKCPGBIB_63
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11340
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11340
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7396:11338]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7397..11338
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..11340
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11340
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             3..911
                     /locus_tag="ctg63_1"
                     /transl_table=11
                     /translation="FSNQYKMKVAGNLFLPKTMKEGEKYPAIIVGHPMGAVKEQSANLY
                     ATKMAERGFVTLSIDLSFWGGSEGEPRNAVLPEVYAEDFSAAVDFLGTRPFVDRNNIGV
                     IGICGSGSFAISAAKIDPRLKAIATISMYNMGTASRNGLKHALTLEQRKQIMAEAAEQR
                     YAEFLGGETEYTGGTVHEVTENSGPIEREFYEFYRTQRGEFTPEGATPMTTTHPTLSSN
                     VKFMNFYPFADIETISPRPMLFITGENAHSREFSEDAYRLAAEPKELYIVPGAGHVDLY
                     DRVGLIPFDKLESFFKEYLKK"
     CDS             961..1824
                     /locus_tag="ctg63_2"
                     /transl_table=11
                     /translation="MKQIKNTHYEGERPLFASHGLYLEEVTIHAGESALKECSDIEAVN
                     CRFEGKYPFWHNDGFVVKNCLFTEGARAALWYSRNLKMKDTLVEAPKMFREMDGVELEN
                     VQLPNALETLWYCRNVELNNVKIDKGDYLFIHGEDIRIKNFVLNGNYSFQYCKNVEIRH
                     AEIHSKDAFWNTENVTVYDSVLDGEYLGWHSKNLRLVNCKISGTQPLCYAHDLIMENCT
                     MADDADLAFEHSSVKATIKGPVHSVKNPRTGNIVAESFGTIILDENLKAPGNCELKLWD
                     GLTCFD"
     CDS             1830..3008
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_3"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.2e-46, bitscore:
                     148.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYNFDEIVPRRGTNSYKWDSAGDADVLPMWVADMDFRTAPSVVE
                     ALKRRVEHGIFGYVRVPDAYYEAITGWFAGRHGWQIEKEWIIYTTGVVPALSAVIKALT
                     TPGDKVIVQTPVYNCFFSSIRNNGCEVAANPLIYTDGTYQMDFIDLERKAADPNVKVLL
                     LCNPHNPAGRVWTKQELTRLGEICLRNNVWVVADEIHCELVFPGHTYIPFASVSEEFLM
                     HSVTCTSPSKAFNLAGLQIANIVSADADIRMKINKAININEVCDVNPFGVEALIAAYND
                     GAEWLEELNQYLFANYHCLRAYFDEYLPEFPVMPLEGTYLVWVDCSALKQSSEDIVKTL
                     LEKEKLWVNEGNLYGEAGEGFVRINIACPRQRLIEGLNRMRRALSSPITSFT"
     CDS             complement(3022..3930)
                     /locus_tag="ctg63_4"
                     /transl_table=11
                     /translation="MEENTKEMIVIDNVDRYNKIFGLETRHPLVSIIDLAKSTTWPTRA
                     WFRYEVYALYLKNVKCGDIKYGRQYYDYQDGTIVCFAPGQITDLEMLPNIQPNAHGILF
                     HPDLIRGTALGQEIKKYSFFSYETNEALHISEEERQTVMDCLQKITSELKHSIDKHSRR
                     LICANIGLLLDYCMRFYERQFDTRNGVNKDIIVRFEHLLNEYFEGDAPQNQGLPSVKYF
                     ADKVFLSANYFSDMVRKQTGKTVSEYIQDKMIGLVKEQLLSTDKTTSQIAYEIGFQYPQ
                     HLSRMFKRVVGMTPNKFRLQS"
     CDS             4135..5025
                     /locus_tag="ctg63_5"
                     /transl_table=11
                     /translation="MLTMMPMAACDGSNADPILPEQPGQPGNSDGGDEDDSTDPTNPIP
                     GGNGRYLVLYCSRTGSTERMAQQIQQTLDCDILEVEPQTPYESDYNGMLNRAQEELAAI
                     RQGNYPAIKTSVEDFGNYDIVFVGYPIWYGSMGTPMQTFLHNHASKLAGKRIALFASSG
                     SSGISASVDEARTLCSGATFTETLLLTSSTLSQMGNRIRTWLETLGASRENNHPSTSTN
                     VKITVGNRTITATMENNAAAQDFLSRLPFEVTLNDYNNITEKIFYPSPALTTAGVTRGC
                     APVPGDITIYDSTKG"
     CDS             5124..5291
                     /locus_tag="ctg63_6"
                     /transl_table=11
                     /translation="MKSFFEGKTHAEIAEEMNLSVKSINRYKQKTMELLRNELKDYLPL
                     FLLFLSPEQL"
     CDS             complement(5265..6371)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 52.9; E-value:
                     7.6e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_7"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-17, bitscore:
                     52.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMIFDRQKQRLLLEGKEYTPGDIHSLVAEGEGNHPSAIWDLYLFL
                     NEWFNDDPVITVHTSGSTGAPKELLVRKDQMIQSARLTCEFLDLKQGETALLCMNLRYI
                     GAMMVVVRSLIAGLNLIVRRASGHPLADVDTPLRFAAMVPLQVYNTFQIPEEKEKLKQT
                     EILIIGGGAVDKALEEKIRNLSNAVYSTYGMTETLSHIALRRLNGAAASDRYYPFSSVE
                     LFLSSENTLMINAPLVCDDTLQTNDIARIYPDGSFTILGRKDNVINSGGIKVQAEEIEK
                     LLQSFIPVPFVITSVPDQRLGQAVTLLIEGQMEISALETKLESVLAPYYRPKYIYQVNH
                     IPQTGNGKINRKECRVLAESLQLLGRQE"
     CDS             complement(6368..7393)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_8"
                     /sec_met_domain="MR_MLE_C (E-value: 1.8e-29, bitscore:
                     92.5, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNRVG
                     IGECAPLPNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQIEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSFKEIELRVDANGAFSPTDAMEKLKRLSELDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGYNTWEEKQRLLSAIRPQYIIIKPSLHGGLAGGEEWIAEAEK
                     LNIGWWITSALESNIGLNAIAQWCATFQNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFC
                     K"
     CDS             complement(7397..8221)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_9"
                     /sec_met_domain="ECH_1 (E-value: 2.1e-82, bitscore: 265.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             complement(8225..9892)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_10"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2e-08, bitscore:
                     23.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPLVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTAESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMVIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKIGQMTPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPLLDN
                     RVPEYPRVWENYCKTIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYQVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIAIGDLSFFYDMNALWNINVRPNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFSNKNKDARILKDYYHQLKQK"
     CDS             complement(9912..11024)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_11"
                     /sec_met_domain="Chorismate_bind (E-value: 1.2e-58,
                     bitscore: 188.3, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     YDLKELNGQRGFVIAPFRVDKSCPIVLIQSDRTGRPLPMEIVADEEQVLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDATFDKLVLSRSLTIRKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLSLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             complement(11021..11338)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_12"
                     /sec_met_domain="HBT (E-value: 8.4e-19, bitscore: 57.5,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VEATMPVDHRTRQPFGILHGGATLALGETVAGLGSMILCQSDEIV
                     VGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLVSSIRVVNSVMKK
                     R"
ORIGIN
        1 ctttttctaa ccagtataaa atgaaagtag ccggcaacct gtttttgccg aagaccatga
       61 aagagggaga gaaatatcct gccattattg tcggacaccc gatgggagcg gtcaaggaac
      121 agagtgcgaa cctgtacgct accaaaatgg cggagcgtgg ttttgtaacg ctgtccatcg
      181 acttgtcttt ttggggtgga agtgaaggtg agccgcgcaa tgctgttttg ccggaggtat
      241 atgcggagga tttcagtgcc gcagtagatt ttctgggtac acgtccgttc gttgaccgga
      301 ataatattgg tgtaatcgga atttgtggca gcggaagttt cgctatcagt gcggccaaga
      361 tagaccctcg tctgaaagcg attgcaacca tcagcatgta caatatgggt acagccagtc
      421 gtaacggact gaaacatgcg ctgactctgg aacaacggaa acaaatcatg gctgaggcag
      481 cagaacagcg ctatgcagag tttttgggcg gagaaactga atataccggt ggcactgtac
      541 acgaagtgac agaaaactcc ggtccgatag aacgcgaatt ttatgagttc taccgcactc
      601 agaggggaga gtttactccc gaaggagcaa ccccgatgac taccacacat cctacgcttt
      661 cgagcaatgt gaaattcatg aatttctatc ctttcgcaga tattgagact atttcgcccc
      721 gtcctatgct tttcataacc ggagaaaatg cccactcacg cgaatttagt gaagatgcct
      781 accgactggc tgctgagccc aaagaactgt acattgtacc cggtgcaggt catgtagacc
      841 tttacgaccg tgtgggtctt ataccattcg ataaattgga atcctttttt aaggaatatc
      901 tgaaaaaata agcatgaaca ggaaaaacag ataactattt aaataaaaga caatcgaatc
      961 atgaaacaaa ttaaaaatac acattacgaa ggcgaacgtc ctttgttcgc atcccacggg
     1021 ctttatctgg aagaagtaac cattcatgcc ggcgaatcgg cattgaaaga gtgcagtgat
     1081 atagaagcgg taaactgtcg tttcgaggga aaatatccgt tttggcacaa tgatggtttt
     1141 gtagttaaaa attgcctttt taccgaagga gcacgtgccg cactctggta ctccagaaat
     1201 ctgaagatga aggatacatt agtggaagca ccgaagatgt ttcgcgaaat ggacggagtc
     1261 gaactcgaaa atgtacagtt gcccaatgct ttggaaacac tctggtattg ccggaatgtg
     1321 gaactgaaca atgtgaagat agataaagga gactatctct ttatacacgg agaagatatc
     1381 cgcatcaaga attttgtatt gaatggcaat tactccttcc aatattgcaa gaacgtagaa
     1441 atccgtcatg ctgaaatcca ttcgaaggat gcattttgga atacggagaa tgtgacagtc
     1501 tacgattctg tgctggacgg agaatatctg ggatggcatt ctaaaaactt acgtttggtg
     1561 aactgcaaaa tttcgggtac acaaccgctt tgctacgcac acgacctgat aatggaaaat
     1621 tgcacgatgg cggatgatgc agacctggct ttcgaacaca gtagtgtgaa ggcaacgatt
     1681 aaaggcccgg ttcacagcgt gaagaatccc cgtacgggaa acattgttgc cgaaagtttc
     1741 gggacaatca tcctggacga gaacctcaaa gctccgggaa actgcgaatt gaaactttgg
     1801 gacggactga cttgttttga ttgaaatata tgaagtacaa cttcgatgaa attgttccgc
     1861 gcagaggtac aaattcctat aaatgggatt ctgccggaga tgcggatgta ttaccaatgt
     1921 gggtagctga tatggatttc cgtacagctc cctctgtggt ggaagcgttg aaaaggcggg
     1981 tggaacatgg tatcttcgga tatgtgcgtg tgcccgatgc ttactatgag gcgataacag
     2041 gatggtttgc cggacgtcat ggctggcaga ttgaaaaaga atggattatt tatacgaccg
     2101 gagtagtacc ggccctgtca gctgtcatca aggcgctgac aactcccgga gataaagtaa
     2161 tcgtgcagac acctgtctat aactgctttt tctcctccat ccgcaataac ggatgcgagg
     2221 ttgccgccaa tccattgatt tacacggacg gaacttatca gatggacttc atcgatttgg
     2281 aacggaaggc ggctgacccg aatgtaaaag ttctgctatt gtgtaatccg cacaatcctg
     2341 ccggaagagt ctggacaaag caggaactga ctcgcttggg ggaaatctgc cttcggaata
     2401 atgtatgggt agtagcggac gagattcatt gcgaacttgt ctttccggga catacttata
     2461 tcccttttgc atctgtctca gaagagtttc tgatgcattc cgttacttgc acctcgccta
     2521 gtaaagcctt taatctggcg gggcttcaga ttgccaatat tgtttctgcc gacgctgata
     2581 tccgtatgaa aataaacaaa gcaatcaata taaatgaagt ctgtgatgta aacccgtttg
     2641 gtgtagaagc cttgatagct gcctacaatg acggtgcgga atggctggaa gaacttaacc
     2701 aatacctgtt tgccaactac cattgtttaa gggcttactt tgatgaatat cttcccgaat
     2761 ttccggtgat gccattggaa ggtacctact tggtatgggt agattgctcg gctttgaaac
     2821 aatcgtcgga ggatatagtg aaaactctgc tggagaagga aaaactttgg gtgaatgaag
     2881 gcaatctgta tggagaagct ggtgaaggat tcgtccgcat caatatcgct tgtccgcggc
     2941 aacggctgat agaaggactg aacagaatga ggcgggcgtt atcatcgcct attacctcat
     3001 tcacctaacc aagatagcgt ttcaggattg cagacgaaat ttattgggag tcatcccgac
     3061 aacccgtttg aacatccggc taaggtgctg cggatattgg aatccgattt cgtaagcaat
     3121 ctggctggta gtcttgtccg tagacaacag ctgctccttc actaatccga tcattttatc
     3181 ctgaatatat tcagagacgg ttttaccggt ctgtttacgt accatgtcac tgaagtagtt
     3241 agcggaaagg aatactttat cagcgaagta cttgaccgat ggcaaccctt gattttgcgg
     3301 ggcatctcct tcgaaatatt cgttgagcag atgttcgaag cggacaatga tgtctttgtt
     3361 tactccgttt cgtgtgtcga actggcgttc gtaaaagcgc atacaatagt cgagcagtaa
     3421 tcctatgttg gcgcagatca gtcggcggct gtgcttgtcg atggaatgtt tcagttcgct
     3481 ggtgattttt tgcaggcagt ccatcacagt ttgccgttct tcttcggaaa tgtggagtgc
     3541 ttcgttggtt tcgtaggaga agaaggagta tttttttatt tcttgtccga gtgcagtgcc
     3601 gcgtataagg tcgggatgaa aaagaatacc atgcgcgttg ggctggatat ttggcagcat
     3661 ttccaggtcg gtgatttgtc cgggagcaaa acagacgatg gttccgtctt ggtagtcgta
     3721 atattgtcgt ccgtatttaa tatcaccaca ttttacattt ttcaagtata gtgcatacac
     3781 ttcgtaacga aaccacgcac gtgtgggcca cgtagtggat ttggccagat cgatgatgct
     3841 gactaacgga tgtctggttt caagcccgaa gattttgttg taacggtcaa cgttgtctat
     3901 tacaatcatt tctttagtat tctcttccat atcacaatct gttttttaat gcgttacaaa
     3961 tataattctt ttctctttaa aatttttact ctcccatcaa aatccatgat tggggtataa
     4021 atatccgtaa atcgtctaca tccgggctgg tccattcccc gtaactttgt aaccggtaat
     4081 ttaacattga aaagagatag taatatgaaa aagattctat taattccatt gatgatgctg
     4141 acgatgatgc cgatggcggc ttgcgacggc tcaaatgctg atccgattct tccggaacag
     4201 ccgggacaac cgggaaattc cgatggtgga gacgaggatg attctacaga cccgacaaac
     4261 cccattccgg gcggtaacgg gcgatatctg gtactttact gttcgcgcac cggcagcacg
     4321 gagcgtatgg cgcaacagat tcagcaaaca ctcgattgcg atatcctgga agtggaaccg
     4381 caaacacctt atgaaagcga ttataatggg atgctcaacc gtgcacagga agaactggct
     4441 gctatccgtc aggggaatta tccggcgatt aaaacttcgg ttgaagattt cggcaactat
     4501 gatatcgtgt ttgtcggcta tccgatttgg tacggcagca tgggcacacc gatgcagaca
     4561 ttcctgcata atcatgcctc gaaacttgca ggtaagcgta tcgctctttt tgccagcagt
     4621 ggcagcagcg gcatctctgc atcagttgac gaggcgcgga cactttgctc cggtgccact
     4681 ttcaccgaaa cattgcttct gacttcttcg acactttcgc agatgggaaa ccggatacgg
     4741 acatggctcg aaacactcgg tgcgagtcgg gaaaacaatc atccgtctac ttctacgaat
     4801 gtgaagatta cagtcggtaa ccgtaccatt actgctacga tggaaaacaa tgccgcagcg
     4861 caggactttc tttcacgtct gccgtttgaa gtgacgctga atgattataa taatatcaca
     4921 gagaaaattt tctatccgtc gcctgcactg actacggcag gagtgacccg tggctgtgcg
     4981 cctgtgcccg gtgatattac aatctatgat tccacaaagg ggtagtcgga acttcttacc
     5041 catccgtcat gtccaatgga tcaccatcaa tgaatcctcc aatgggtaaa ctccattttt
     5101 atggctatat atttccgtaa gttatgaaaa gtttctttga aggcaaaaca catgcggaaa
     5161 ttgccgaaga aatgaatctc agcgtaaaat ccattaatcg gtataaacaa aaaacaatgg
     5221 aactcctgcg gaacgagttg aaagattacc tcccgctatt tttattattc ctgtctcccg
     5281 agcaactgta agctctctgc taaaacacgg cactctttac gattaatctt cccatttccc
     5341 gtttgaggaa tatgatttac ctgataaata tatttaggac gataataagg tgctaagact
     5401 gattccaatt tagtctctag cgcacttatt tccatctgcc cttctatcaa taaagtaaca
     5461 gcctgcccca aacgttgatc cggaacggaa gtgattacaa acgggacagg aataaacgac
     5521 tgaagtaact tttcgatctc ttctgcctgc actttaattc ctccgctatt gattacatta
     5581 tcctttcttc ccagaatcgt aaaactaccg tccggataaa tgcgggcaat atcatttgtc
     5641 tgcagagtat catcgcagac aagcggagca ttaatcatca aagtattttc tgaagacaaa
     5701 aacaactcta cggatgaaaa aggataataa cgatcggatg ctgctgcgcc attcagacgg
     5761 cgaagagcga tgtgagaaag ggtttccgtc atcccgtaag ttgaataaac agcattggac
     5821 agatttctga ttttttcctc taaagccttg tcaactgctc cgcctcctat aattaaaatc
     5881 tccgtttgct ttaatttctc tttctcttcg ggtatctgaa atgtattata cacctgcaaa
     5941 ggcaccatag ccgcaaacct taaaggagtg tccacatctg ccaatggatg accggaagcc
     6001 cgacgtacta taagattcaa cccggcaatc aaagaacgga cgactaccat catcgccccg
     6061 atatagcgaa ggttcataca caataatgcc gtttcaccct gctttaaatc cagaaactca
     6121 caagtcaggc gtgcactctg tatcatctga tctttgcgaa caagcaattc tttaggtgcc
     6181 cccgtagaac cggaagtatg tacagtgatc acaggatcat cattaaacca ttcgtttaga
     6241 aaaagataca agtcccatat agcagaaggg tggtttccct caccttctgc tacaaggcta
     6301 tgtatatcgc ccggagtata ttcctttccc tccagcaaca aacgctgttt ttgtcggtcg
     6361 aatatcatca tttacaaaac cacaaacaat cttttctgat ttcaagaggc atctctacat
     6421 tatctgtaaa gagtaacccg gtgcctaacc cttgcggcaa tggattctga aaagtagcac
     6481 accattgagc gatagcattc agaccgatat tagactccag agcagaagtt atccaccaac
     6541 cgatattcag tttctccgct tctgcaatcc actcctcgcc accggctaat ccgccatgaa
     6601 gagaaggttt gataataata tattgcggac ggatagccga aagtaatctt tgcttttctt
     6661 cccaggtatt atagcctatc agttcctcat ccaaagctat cggcaaagga gattcggaag
     6721 taagacgtgc catttcttcc cattgtccgg cacgaatggg ctgttctatc gaatgtaagt
     6781 ccagttcgga caagcgtttc aatttctcca tcgcatctgt tggcgagaat gctccgttgg
     6841 catctacacg caattctatt tctttaaaag aatagtgaga gcggatatgt tggagtaaag
     6901 ccagttcttc ttcaaagttg atggcaccga tcttcaactt tatacagcgg aatcccgcct
     6961 ccatcttctt ctctatctga gcaagcattc tattgaagtc acccatccag ataagcccgt
     7021 ttatcggaat acctgcttcc ccacgtgaga agggtgtatc ccacaaagcc cagcttcctt
     7081 caaaaaagtg acgaatggct gtctccaagc caaaaaggat ggaagggtac ttgcatagag
     7141 cttccatgtc cagcttacct ccctgattct ctacctgccg gcagatttta gccagcactt
     7201 cctcgtaatc gggaagatca tcacagctaa gatttggcag aggagcgcac tccccgatcc
     7261 ctacccgatt gggaaattcg ggagcagtaa aatgaagata ccagactttt cgcgttgtgt
     7321 atgtgcctcg tgaagttccg gccggctgct tgaaatgaag cacccgcgga ataatgtcta
     7381 ttttgcaatc cattgtttaa gggaacttcg gatatttctt aaagttaggt ttacgtttct
     7441 ccagaaatgc attctttcct tcctgagcct catccgtcag atagtaaagc aaggtcgcat
     7501 cccctgccag ctcctgaata cctgcctggc cgtccagttc ggcattcaat ccggctttaa
     7561 tcatccgcaa ggccaacgga ctgagcagca tcatttcttc cgcccattgc acatactcat
     7621 cctccagttg ctccaatgga actactttat tcaccaatcc catatccaac gcttcctgcg
     7681 cattgtattt ccggcaaagg aaccatatct cacgtgcctt cttctgaccg acgacacgag
     7741 ccagataaga ggctccgaaa cctgcatcaa agctacctac acgaggaccg gtctgtccga
     7801 agatcgcatt ctccgaagca atcgataaat cgcaaactac atgaagcacg tgtccgccac
     7861 caatggcaaa tccatttacg gcagcaatta ccggtttcgg aatgctgcgg atttgtttct
     7921 gtacatccag aacactcaga cggggaacac cgtccttgcc gatatagccg ccacgccctt
     7981 tcacattctg gtcaccgccc gaacagaaag ccttgtcacc agctcccgta atcacgatca
     8041 catcaatatc cgcttcttcc cggcaaatgc gcaatgcgtc actcatttca gccgttgtag
     8101 tcggagtaaa tgcatttcga tagcgttcac ggttaatggt gatgcgggca atcccattat
     8161 agtaatcaaa gaggatatct tcgtattctc tgatggttgt ccattctctt tgtgttgaca
     8221 taatctattt ttgttttagt tgatgataat aatctttcag tatacgtgca tctttatttt
     8281 tattgctgaa tacttccatc agaaccggtt gttccatggc ttccggttgt gtgaaggttt
     8341 tcatcgcttc ggcaagctgt tcttcattct ctacccgttg ataaaggaat ccgcgttctt
     8401 ccgcccatcc tttggcagat gtcttgtgaa cggctgtaat atacttgtgc gatgtacccg
     8461 acatatccag tccgggtaat gtatggaaaa tctcccctcc tccgttattc agcaaaagaa
     8521 tgcgtagatt aggacggaca ttgatattcc acaaagcatt catatcataa aagaaactaa
     8581 ggtcacctat agctataaaa tttagtttat ccgaaccggc agcatatccc actgccgtgg
     8641 acaacgagcc ttcgatgccg cttgtacccc gattacagca tacctcaatc gtagaaggaa
     8701 cctggtataa ctgagcatag cggataacag aactatttgc cagatgcaat gcacatgatt
     8761 ccggcaatgc ttttatcaaa gcaccgatag ccgacatttc cgaatatccg aactccggtt
     8821 cgggaatggt cttgcaataa ttctcccata cacggggata ctccggcacg cggttatcca
     8881 gcaatggagc tattttctcc agaaactcaa acgggtccat ttcgatgacg gtagtcagag
     8941 aaccgtaaag gtcaaccact tctccatcag cagacacatg ccagtgttct ttaggcggat
     9001 gctgccgaag atattttttc aaccgcttgg aaaccacatg tccgccataa gtaatcagta
     9061 gttcgggagt catctggccg attttctctt cgggcatcgc ataaagcgcc gcatcaaaat
     9121 tcttcaccgg aataccgggt actgtctgat taccgatatg ctcggtcagc cacacgaaat
     9181 gtttatataa caatttggta tgccgtttct caaacaagta aatcaagttc atctgtccga
     9241 caataaccat ccgcttctga tatctgttca agcgttcgat caggtcattg taatcccggt
     9301 cgtatacatt cagaccctga tagcgcgtga taacacgtac ttcgggaagc gactccgccg
     9361 taaactggaa caaaggttcg gatataggaa tattaatatg taccggacct tttccatgat
     9421 ggttggtttc cagcaatgct tcattcacca agcggttaca gtaccattca tcctcttctg
     9481 tctgaatctc cggaaggttt accgatttct tgaccaatgt ctgaaaaaca ccgggctgcg
     9541 gcaatgtctg tcccgccatc tgtccaatcc aggcagcagg ccgatcggca gagatcacaa
     9601 ctaaaggtat attctgataa tacgcttctg ccacagcagg atgaagattg agcaacgctg
     9661 taccggaagt acagcaaacg gcagcaggat gcccgccatt cagcgcaaga ccaatcgcaa
     9721 aataaccggc actccgctca tccgtcatag cataacaagt aaaacccgga tgagtagaca
     9781 gcgtatgcac aagaggtgca ttacggctac cgggacataa cactactttc gtaattccat
     9841 gcgcctcaag caacgcgacc aactggagta tatttttctt gtccgaatac atattaatag
     9901 tgattagctt gttaatgatt catcattatt ggagcagaca caagaatacg cctcattgtc
     9961 tgcaatttct tttccgtttc ctgccattca tcattcaact ctgaagaggc taacaatccg
    10021 ccaccggcat acagtgtcag ttgctcgtct tcaatgtgca tgcaacgcag attcacatac
    10081 aaatctgtgc gtccctccgg atcgagccaa ccgataaaac cggaataata cttacgatcg
    10141 tacccttcat tttccaaaat gaaccggtag gcttcttctt taggcagtcc gcacacggca
    10201 ggagtcggat gcaggacttt cagaaggtct cccagatttt tattatcttt caaagagaaa
    10261 tgaaaatcag ttttcagatg tgacagggcg ccggcatatg ccggataagg cccgctctct
    10321 gtagagcgaa tgcccagcga aagaagctgc cgacggatat aggacgccac ataatcctgc
    10381 tcctgacggt ttttgtcatc ccatacttgc ggaagtttac cattctgcaa aggttgagtt
    10441 cctgccaagg caactgtatt ccattcattt ttttcgcccg acaatataat ttcgggggta
    10501 cttcccagcc acacgcccgt ctgaggagta taacacagat agatataaga atgaatataa
    10561 cgttgacaag ctgcacgaaa aacagctgaa ggggaaaact ccggattctt tctaatagtg
    10621 agactacggg aaagcaccag tttatcaaag gtagcatcac gcaaggcttc aataaatgta
    10681 tgaaaacagg tcgcatactt ccctgtacaa agggtatgaa aagattcctc cggataactt
    10741 tgcaagacct gctcttcgtc tgccacgatt tccataggca acggccgtcc agtcctgtcg
    10801 gactgtatca acacaatcgg gcatgactta tctacacgga acggagcaat cacaaatcct
    10861 ctttgtccat tcagttcttt caaatcgtaa atcaggcgga cagctccgac atcttcagtc
    10921 aacagacgag gatacttctc cccgggaaca cgataaacag caaagggctg tttccgctga
    10981 ataagtgcat caatagttgt caagttactt ttttcgtcaa tcatcttttt ttcatcacac
    11041 tgttgaccac ccgtatagag gacaccagtt tattggttga agtaaaaacg tccacattcc
    11101 agacatggga ggaacgtcct ttatgtacaa tcgtcgctac tgcacgtact gtatcacctt
    11161 cgtgcgcaga agatatatga tttccgctga cctgcattcc taccacaatt tcatccgact
    11221 gacagagaat catcgagccg agtccggcaa ctgtttctcc caatgcaagc gtagctccac
    11281 cgtgcaaaat accgaacggc tgacgggtac ggtgatctac tggcatcgtc gcctctacac
//
