LOCUS       gnlProkkaCMLOHLMF_55   16002 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CMLOHLMF_55.
ACCESSION   gnlProkkaCMLOHLMF_55
VERSION     gnlProkkaCMLOHLMF_55
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 20:17:25
            Original ID  :: gnl|Prokka|CMLOHLMF_55
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16002
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16002
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5735:6002]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5736..6002
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..16002
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16002
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(48..227)
                     /locus_tag="ctg55_1"
                     /transl_table=11
                     /translation="MFVYPLFRPSHCPFPGYTTVTHVVCVYTIPPDGRKPYKHRREHPC
                     CYLQGNFQSCEFPQ"
     CDS             276..491
                     /locus_tag="ctg55_2"
                     /transl_table=11
                     /translation="MKQNTPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             505..4083
                     /locus_tag="ctg55_3"
                     /transl_table=11
                     /translation="MMKLRNLMQVACMATAALTAFSCSQEEFENSGRKGNITVNATFEG
                     AGTDTRTTVNDKYKILWQDTDALGLFCSNAESNYSNTKLEYASGAGQTSATFNGSKPSG
                     ETAVFSIYPYQQNMSVSGNTLTMTLPATLTNYNGSSNGPMYAKVTNPDNLSALSFKHMA
                     AMIKLTVNKIPAEATTFKIIASNNIAGICTVDLTAADPILAVTSDESKEITASFTASAD
                     IKSRNFYIPLPTGTYSSITAQLTNGSDKVYFTKTLNDKILGRRDILVVPPLDCVVVEAT
                     TPSALSTALADSKNLPQEAPTAATVTDIAVSGSFNTTSGSNDGIAIPVLQNSDINLAFN
                     TAPTTSTSAPLKLTDKTNTSVSTPAATATNSVSLAVPETTAEQEAPSVAITMPSTTVTL
                     AAVGNKATYNEVTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGNTTIYI
                     IKGTEASLPATIDSKFVVQSDVAVLKTAFANGEDFKLSADADITGQSVSVPAGKSVVLD
                     LNGYTLTADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGEDAS
                     MTMESGNISAVRETPDSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNSIIN
                     ITDGELISTADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGTGST
                     GNWGDGTGGLDCAAINVSGAYGIATVNIKGGTLIAEAKSLITEGTTYTPVINVTGGTFS
                     DPSALKYMKANANVNIKLTADKTCPGFKTTSGQTLTMDLGGKILTLADPTVGSTGTETN
                     SCQLLEGSNVTFKNGTLKSDNNKIMIQNYCNLTLDNMTVEDTNAQYVVSNNCGNISINN
                     TTINAGSNANQFAFDVCGYAKYTAGVTVTVSGTSVINGKVEISKSAGNTELMKLNITSG
                     TFNGDLKVDASVGTKNAQSIISVSGGTFSDPSVLKYMATNATVDIKLLSNINIAKTELA
                     TGYILNAANATANLNLNGHDIINSSETADATPFTQIFTVQNGTLNISGNGNVKCDASAT
                     AKDDGYRMVIEARGYGTVNIHGGSYYNTQKLNTQIDLIYARENGKINIYGGTFESGKYG
                     TPNNDTDGRYWVLNLKNTDKNTASIQVSGGTFINFNPANPNMDDNESYLVTGYEVTRDG
                     SVYTAAHKVGDGRKEYIVGQTSQENR"
     CDS             4330..5256
                     /locus_tag="ctg55_4"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETTTKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVATVTEL
                     ATLAPVYHLKCLPDREATELCRKTVEG"
     CDS             5283..5723
                     /locus_tag="ctg55_5"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVTVLARDLTERIVFHRIIRRNGDILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             5736..6002
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_6"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 9.5e-14,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.5e-16, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             6011..7174
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_7"
                     /sec_met_domain="NTP_transf_5 (E-value: 2.9e-46, bitscore:
                     147.6, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRVLYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRHFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRSKGVKDKKARTKK"
     CDS             7197..8867
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 277.6; E-value:
                     3.6e-84)"
                     /gene_kind="transport"
                     /locus_tag="ctg55_8"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHIAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTTAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLSGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVFDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPELELKDVTFRYTPDDRPVFSRFSCRFPAGSCIAIVGETGKGKTTLIRLLLALATPQ
                     EGQILLIPAKHPLETNHTVSPQTRKNFVYVPQGNTLFSGTIRDNLLMGNPQASQEAIYQ
                     ALQTATADFVFHLPDGVDSPLSERGGGLSEGQAQRIAIARALLRPGNILLLDEATSALD
                     PDTERLLIKNLRRDCAGKTCIFVTHHPAVAEACESIVRL"
     CDS             complement(8912..9823)
                     /locus_tag="ctg55_9"
                     /transl_table=11
                     /translation="MKPTLFLLAAGMGSRYGGLKQLDGLGPNGETIMDYSIYDAINAGF
                     GKLVFVIRKDFEQDFRDKIISKYEGHIPCELVFQSIDDLPEGFTCPEGRTKPWGTNHAV
                     MMGADVIKEPFAVINCDDFYGRDSFQVMGKFLAALPEGSKNVYSMVGFRIGNTLSESGT
                     VSRGLCGTDANNLLTSVVERTKIQRMDGEVKYIDDNGEWTATPETTPVSMNFWGFTPDY
                     FAYSAEFFKSFLSDPKNMENLKSEFFIPLMVDKLINDGTATCEVLDTTSKWFGVTYPED
                     RQSVVDKIQALVDAGEYPAKLF"
     CDS             complement(9949..12303)
                     /locus_tag="ctg55_10"
                     /transl_table=11
                     /translation="MKRLILYIAGLIFLAGCSTTKHLPEGEILYTGQKPMIVLNRSETS
                     VGEIAMEEVEAALATAPNNSLLGSSTIRYPFPFGLWIYNGFQKYEKGFGKWIFNKFAAT
                     PVLMSTVNPDIRQKAAVNLLRDYGYFNGSVSYKTFIDPKDSLKAKLQYTVNMRNPYFID
                     TVYYRGFSERTTRIMELGRRRSLISSGEQFNVADLDGERTRISTLLRNVGCYYFRPDYL
                     TYQADTMMVPNGHVQMRLIPVPGMPKVAEKQFRVGRKSVYLLGKQGQEPNDSMDYKGLT
                     IHYYNKPPVRPNMLYRWLNYQGYRRKRQIQDSAGIARQRSMQSLYSLYRQTRIQERLAS
                     VGIFRYAEMQYIPRDTAFVSDTLDVRVIAALDKPYDAELDFNVTMKSNNQTGPGAAFTV
                     TKNNVFGGGESWNVKLNGSYEWQTGKASSSLMNSYELGISTSLIFPRVVFPRMGDREYD
                     FPATTTFRLYADQMNRAKYYKLLAFGGNVTYDFQPKSTSRHSITPFRLTFNVLRNPTAA
                     FDTLRAENPALYVSLRDQFIPAMEYTYTYDNASVRGKRNPIWWQTTVASAGNLTSAVYR
                     IFGKPFSEEGKKLFGVPFAQFLKLNSEFRYHYRIDKNQMIASRIAGGVIWSYGNATTAP
                     YTEQFYIGGANSVRAFSARSIGPGGYPPETDRKYTYINHVGDIRIEANIEYRFRMIADL
                     HGAVFLDAGNVWLMRKDENRPNGEFTLKNFPKQIALGTGFGLRYDLDFLVFRLDLGIGL
                     HDPYDTGKSGYYNIPKFKDSMALHFAIGYPF"
ORIGIN
        1 atattaatct gaacctctgt tagatacgct gtcaaagttg ttgccgctca ctgcggaaat
       61 tcgcaacttt gaaaatttcc ctgaagataa caacaaggat gctcacgtct atgtttatat
      121 ggttttctcc catcaggggg gatggtatat acacaaacga cgtgagtgac tgttgtatat
      181 ccagggaaag ggcaatgcga aggcctgaat aaaggatata caaacatagt tactcacgtt
      241 ttttttattg tttaaccttt aaataatttg tgtatatgaa acagaacaca ccagacggta
      301 gagaagcata catcactccg tctatcgaag ttatcaaaat ggagaatgaa ggagtcattg
      361 caacaagcgg cgaaccttac catcccatta cgcgctccta ttcgggcagc acctctaccc
      421 atagctacaa ttcggcatcc agcagcgact tggaagacct aatcaatgac atcttaaccg
      481 tagaaaacta agggggactt cattatgatg aaattaagaa accttatgca agttgcctgc
      541 atggcaactg ctgccttgac cgcattcagt tgcagccaag aggaatttga aaacagcggg
      601 cggaaaggaa acatcaccgt taacgcaacg tttgaaggcg caggtaccga cacccgtact
      661 accgtaaacg ataaatacaa gattctatgg caagataccg atgccctagg gttgttctgt
      721 agtaatgcag aaagtaatta tagcaataca aaattagaat atgcaagcgg tgctggtcaa
      781 acttccgcca ctttcaacgg cagcaagcca agcggagaaa cggctgtatt ctccatctat
      841 ccttaccaac aaaacatgag cgtaagcggc aatacattga ccatgactct acctgccacg
      901 cttacaaatt ataacggcag cagcaatggc ccgatgtatg ccaaggtgac aaatcccgac
      961 aatctgagcg ctctgtcctt caagcacatg gcagccatga taaaactgac cgtcaacaag
     1021 attccggcag aggccactac cttcaagatt attgcctcca ataacattgc aggtatttgt
     1081 acggtagact taaccgcagc agacccgata ctggcagtaa cgagcgatga aagcaaggaa
     1141 atcaccgcct ccttcacagc ctcagctgat ataaagtctc gcaacttcta cattcctttg
     1201 cccacaggta cttatagttc catcactgcc caactgacga atggaagcga caaggtatat
     1261 tttaccaaga cgcttaatga caaaatctta gggagaagag acatattggt agtacctcct
     1321 ttggattgcg ttgtggtaga ggctacaacc cccagtgcgc ttagtacagc tttagctgat
     1381 tcaaaaaatc tcccacaaga agcaccgaca gcagcaaccg taaccgacat tgcagtcagc
     1441 ggcagcttca ataccacttc tggcagcaac gacggcatcg ccatcccggt tttacagaac
     1501 tcggacatca acctggcgtt caatacagcc ccgacaacca gcacttctgc cccgttaaag
     1561 ctgaccgaca agaccaatac cagcgtaagt actcccgccg ccactgccac caacagtgta
     1621 tccttggctg tgccggaaac cacagcagag caagaagctc cttctgtagc catcaccatg
     1681 ccaagcacca ccgttacatt ggcagcagta ggcaataaag ccacttacaa tgaagtgact
     1741 gccactaccg cccagcagac attgattatc aatgcaggcg tcaccgtaaa gaagctgacc
     1801 gtaaaaggcg gtaacttgaa gatatatgga aaggtagaac aattggtaca cgatgccggc
     1861 aataccacaa tctatataat aaaaggaact gaagcatcac ttccggcaac aatcgacagc
     1921 aaatttgtag ttcaatccga cgtggcagtc ctaaagaccg ctttcgccaa cggcgaagat
     1981 tttaaattgt ccgccgatgc cgacatcaca gggcaaagcg tcagtgtacc cgccggaaag
     2041 tccgtggttc ttgacttgaa cggatataca ctgactgccg acaacagcgc aacaggcaaa
     2101 atcatcgtct tgggcaagat gacactgaag gacagctcta ccgagaagaa aggcaagata
     2161 gttgccagcc aggattatac agcggcttct tataatggca gtctgattga aatagccggt
     2221 gaagatgcct ccatgaccat ggaaagcggc aacatcagtg cagtcagaga gactccggac
     2281 agtaacggcc aatatggcgt cggagtgacg gatggtggag acttcaccat gacaggcggc
     2341 aagatagaag ccggatggtt tgcagtggca ggcaacggca attacaagac gcagaactcc
     2401 atcatcaaca tcacagacgg agaactcatt tctactgctg actatgcagt ctatctgccc
     2461 caatccggca caacgaccat cagtggcggc aaggtttatg gtgccgcagg aggtgtatgc
     2521 atccaacgag gcactctgaa tgtggaaggt acagccttga ttaccagtaa aggcacaggt
     2581 agcaccggca actggggcga cggtaccgga ggactggact gcgccgccat caacgtaagt
     2641 ggagcatatg gcattgccac agtaaacatc aaaggcggta cactgattgc cgaagcaaag
     2701 tcactcatca cagaaggcac cacttataca ccggtcatca acgttaccgg cggtacattc
     2761 tccgacccaa gcgcgctgaa gtacatgaag gcaaatgcaa atgtgaacat aaagttgacc
     2821 gccgacaaga cctgcccggg attcaagacc acaagcggac aaaccttgac gatggactta
     2881 ggcggcaaga ttcttacact tgctgacccg accgtaggtt ccaccggcac cgaaacgaac
     2941 agctgtcaat tactcgaagg ttcaaacgtt actttcaaga acggaacgct gaagagtgac
     3001 aacaacaaaa tcatgattca gaactactgc aacctgacat tagataatat gacagtagaa
     3061 gacacaaatg cccaatacgt agtaagcaac aattgtggca acataagcat caacaatacc
     3121 actatcaacg caggaagcaa tgcgaatcaa tttgcattcg acgtatgcgg ctatgcaaag
     3181 tacactgctg gagtcacggt tacggtaagc ggtacgagcg tcatcaatgg aaaagtggaa
     3241 atttccaaga gtgcaggaaa taccgaactt atgaagctga atatcacaag cggtactttc
     3301 aacggtgact taaaggtaga tgcatccgtg ggaaccaaaa atgcccaaag tatcatctct
     3361 gtttccggcg gtacattctc cgacccaagc gtactgaagt acatggcaac caacgcaact
     3421 gtggatataa aacttctctc aaatatcaac atcgccaaga cggagcttgc cacaggctac
     3481 atattgaatg ctgcaaacgc aacggcaaac ttaaacctga atggccacga catcatcaat
     3541 tcctcagaaa cagctgatgc cactcctttc acacaaatct ttactgtaca gaacggaaca
     3601 ctaaacattt caggcaacgg caatgtgaag tgcgatgcat ctgctacagc gaaagacgat
     3661 ggttatcgca tggtaattga agcccgagga tacgggacag taaatattca tggcggttct
     3721 tactataaca cccagaaact gaacacccag atagacctga tttatgcaag agagaatggg
     3781 aaaatcaata tctatggagg aacatttgaa tccggcaaat atggtacacc caacaacgac
     3841 acggatggca gatactgggt actgaactta aagaatacag acaagaacac tgccagcatc
     3901 caggtgtccg gtggaacgtt catcaatttc aacccggcaa atccgaatat ggacgacaat
     3961 gagtcctatt tggtaacagg ctacgaggtt acccgtgacg gcagtgtata tacagcagcc
     4021 cacaaagtcg gtgatgggag gaaagaatat attgttggcc aaacaagtca ggagaaccga
     4081 taagccaaat tctaagaaag gaagcaatat atcctcgcaa accaaacgaa gagatatcgg
     4141 aatcgcctta ttactatctt ttagatgcgg cggacagcgg attttctttt atagatctgc
     4201 gtcctccgcg tctaaagaat gacaacaaga cagttgaaaa atctctcaaa tcttcctcat
     4261 tcacacaaac attcattatt tttctgagta gcccaaagta tcatgaataa caactaacaa
     4321 tcaaaacata tgagaataca gatattggat tatcaagtag gaccgcacac ctttcgcatg
     4381 gtgaaacctt ccgacttcaa tatattcaag gcgctgcctt cactgattcc gttcatcacg
     4441 acaatagaca cgacgcaaaa agtaatcttt gaaacagaga tagacgatga cgaaacaacg
     4501 acaaaacgaa ccatagcgaa aactcccgat gatatatgtt tcaactggga agatgccgat
     4561 tgcatcattc gccctttgcc ccacagctca caccttgtat ccatcacccc acggaaaagc
     4621 gggaaaaact attggatgga gtgcaacgat aacttcaggc aatgcttcat ccacctaccg
     4681 gcctgcagga cagaaacacc ggctccggaa aacgaaacga acttcgtact gaacaacttc
     4741 ttgatgatgc tctatgcctt caatgccgcc cgccaccata cactgctgat gcatgcctcg
     4801 gttgtcgcta ctgaaacagg caaaggctac ctcttcttag ggaaaagcgg cacgggcaaa
     4861 agtacgcaca ccgggctctg gctgcaacag ttctcggact gccatctact gaacgatgac
     4921 aatccgatag tacatgtgga cagcctcggc aagcaagcca ctgttttcgg ttctccgtgg
     4981 agcggaaaga caccttgcta tcggaaagaa tccatgaccg taggcgcctt cgtccgcttg
     5041 gaacaagcac cgcagaatga aatagagcaa gagagagcag cacatgcttt cgccaccctc
     5101 ctcccctcct gctcttgcct aaagcagaac aaggaaatct ataacgccat tgtcgccact
     5161 gtgacggaac ttgccacgct ggcacccgtc tatcatctga aatgcctacc cgaccgtgaa
     5221 gcgacggaac tttgcagaaa gacggtagaa ggataagtta tgaatgatga actgaacagc
     5281 cgatgaagaa aagcattccc aacgagatat tgcttcccga agtggcgcgt ctcatcaaag
     5341 agggacatac agtaaccatc accgtgcggg gcaacagcat gaatcctttc ttagtggacc
     5401 gccgtgaccg ggtgacactg ggcgatttca ccacagaaca gctgcaaccg ggcgtcaccg
     5461 tactggcacg cgacctgacg gaacgcatcg tctttcaccg catcatccgt cggaacggag
     5521 acatactcat cctgcaaggc gacggcaacc tcgcccaaac cgaagaaacc gacatcggac
     5581 gggtaatggg cgtcatgacc gaagccatgc gaaaagacaa acggtacacc gccgacggca
     5641 aagtctggaa gctctactcc tactggtgga tgaagctaaa ccccgctcgc cgctggctgc
     5701 tcgccctgtt cagaagaata taaaacaaaa taaccatgaa aatcaaacaa ggatttatcc
     5761 tgcaccggat aggcgatgac tacatcatca tgcaagacgg ctcgtcgaac gtggacttca
     5821 gcaaagtcat cagcctgaac caaacttccg ccatgctttg gcaagagata gaaaacaaag
     5881 agttcgatac agacagcgtg acagaagccc tgaccagccg ctatgatgta gataacgaat
     5941 cggcccgtcg cgatgcgcag aagtttatcg actcccttga ccgcgaagga atcatagaat
     6001 aaggacggat atgcaacacg ctttcttttc attggtacgc tccggcctgt ggggcactcc
     6061 ggcagaccga caactcttcc ggtcggtctc gccggacgac tgggaaaccg tgtaccgcat
     6121 ggcaaactca caagccctgc ttgcactgac ttttgacggc ataagcagtc tgccggccga
     6181 actgcgccct ccacgcgtcc tctatctgaa atgggctgcc cggactgcac agatagaaca
     6241 agccaacaaa cgcctcaacc agcttctgcc cgaactcaat accctttacc gggaagccgg
     6301 gctgcatccc gtactgctga aagggcaagg catcggcacc aactaccgca ctcccttgca
     6361 ccggcaatgc ggagacatcg acatctattt aggaaaacaa gggcaaccca tagccaatcg
     6421 cctcctgctg caacaaggcg ccatagtcga gggagaagcg tccgacaagc atgccagcta
     6481 cagtttgaaa ggagtacaca tcgagaacca ccgcatcatc ctccggctga acagtccgct
     6541 tgccaaccgg cactttcagc agattatcag aaaatggtac ccgcaggaaa cagactatgc
     6601 cctattctcc gaaaccggga aagaggactc gaaggccgtc agtatcgcca tacctccggc
     6661 caccttcaat gcactttata tcttcctgca tgcctttgta catttcctga acagcggaat
     6721 cggcctgcgc cagctatgcg actggacttg tctgcttgcc aatcgccaca aagaaataga
     6781 tgccaccacc ctgcttcgcc agttgcagga cctcggacta ttgcatgccg cacaagcatt
     6841 cggctacatt gccgtcaccc gactgggatt gcccgctaac cggcttcctt tccccttgga
     6901 aggcaccaag cagataggag aacaattatt ggaagacatc ctgtctaccg gtaacttcgg
     6961 gcaacatgat aaccgcatca agccacgccc caaaggatat tgggcaggaa agtggtacac
     7021 cttctgccgc gccacccgac gctgcaacga actgcgtcaa tttgcaccgt acgaagcact
     7081 ctggtatccc gtgactctga tagggggaac gatagctata caaataaacc gatcaaaagg
     7141 agtaaaagac aagaaagcaa ggacaaagaa ataaaagaac ccggaaaata aaaggaatga
     7201 aaaagcaaca gaaggacaaa aaagtgaaaa aggacagacg tgaaaaactt aggtatattc
     7261 gagaggtatc tgccgaacaa cgcggacgta tcctgctaag ttgcctcacc ggcattctgg
     7321 gcgtggcctt tgccctagcc tttatctatg caaccaaacg ggtgatagac accgctaccg
     7381 gaataacaga cgacaacctg acgcatatcg ccgttctcac cgttgtcctg ctgactgccc
     7441 aattactgtg cggagctgct gacacttgga taagtacccg tatgcagata gagacgggca
     7501 acgcccttcg ccaccgcctc ttctcgcgct tactgcaaag ccgctggaac gaattggagc
     7561 gtttccatac cggagacgta gtgaaccggg tagaacaaga caccaccgcc atcgtcacat
     7621 tgctcacctc ttctgtcccg gcattcatcg tcacgagtat acaactgctg gcagcctttc
     7681 tattcttcta ctttttagac ccttcactgc catggctgat tgttgccatc ctgcccgtct
     7741 ttctatcagg cagccgtttc tatatgcgac gaatgaaacg ctatacacat gatattcgga
     7801 acagtgacgg tcgcatccag tccgtcatac aagagagcct gcaacatcgc atagtgatta
     7861 aaacattgga acaaggcgaa cggcatctgg acaaactcga tgacttgcaa gacatgctcc
     7921 acagccaagt catgggacgt acccgtttct cgctttctgc ccacatgtta gtggcccttg
     7981 ccttttccgg cggatacctc acggcttttc tttggggagc cgttcacctc agcgcaggct
     8041 gtatcacctt cggaacgatg accgcctttt tgcaattggt aggaaaagtc cagcgtcccg
     8101 tgttcgacct ctcacgcctg ataccttccg tagtcaatgc ccttaccgcc atagaccggc
     8161 tattggaatt ggaaagactg ccggcagaag cggatggtga cagcatattc ctcgcctcta
     8221 ccccggaact ggaactgaaa gacgtgactt ttcgctacac tcccgatgac cgtccggtat
     8281 tcagccgctt ctcctgccgt ttccccgccg gtagctgcat agctatagtc ggagaaacag
     8341 gaaaaggaaa gacaacgctc atccggctat tgttggcact ggcaacgcca caagagggac
     8401 agatactctt gatacccgcc aaacatccac ttgaaaccaa tcataccgtc tctccgcaaa
     8461 cccgcaagaa cttcgtatat gtcccgcaag gcaataccct tttcagcgga actatccgtg
     8521 acaacctgct gatgggaaac ccacaagctt ctcaagaagc catatatcaa gccctgcaaa
     8581 ccgccaccgc cgacttcgtc ttccaccttc ccgacggcgt agactcccca ctcagcgaac
     8641 gaggtggtgg actcagtgaa ggacaagccc aacgcatcgc cattgcccgc gctctgctac
     8701 gccccggaaa cattcttctt ttagatgaag ccacttctgc cctcgacccc gacacggaac
     8761 ggctgttaat aaaaaacctg cgcagagact gcgcaggcaa aacatgtatc ttcgtcaccc
     8821 accatccggc agtagcggag gcatgcgaat ctattgtccg attataatca gagaataagc
     8881 cccaacgggt atctgccttt ggttaacaaa ctcagaacag cttcgcagga tactcgcccg
     8941 catccaccaa agcctgaatc ttgtcgacta cactctgacg gtcttcggga taagtcacac
     9001 cgaaccactt gctggttgta tcaagcactt cgcaggtagc agtgccatcg ttaatcagct
     9061 tatccaccat cagcgggatg aagaattcgc ttttcaggtt ctccatattc ttcgggtcgc
     9121 tcaagaaact cttgaaaaac tctgcactgt aagcaaaata atcgggagtg aaaccccaga
     9181 agttcatgct gaccggagtc gtctcgggag tggcagtcca ttcaccgtta tcgtcgatgt
     9241 acttcacctc accgtccatg cgctgaatct tggtacgttc cactacggaa gtcagcaggt
     9301 tgttcgcatc cgttccacac aatccacggg atacggtacc gctctcgctc aacgtattgc
     9361 cgatgcggaa gcctaccatg gaatatacgt ttttggagcc ttcgggaagg gctgcaagga
     9421 atttgcccat tacctggaag gagtcacgac cgtagaaatc gtcgcaattg ataacagcaa
     9481 acggttcctt tattacatcg gcacccatca ttacagcatg gttggttccc caaggtttgg
     9541 tacggccttc ggggcaggtg aagccttcag gaaggtcatc tatggactgg aataccagtt
     9601 cgcagggaat atggccttcg tatttggaaa taatcttgtc gcggaagtcc tgttcaaaat
     9661 ctttacggat tacgaaaacg agcttgccaa aaccggcatt gatggcatcg taaatagaat
     9721 aatccatgat agtttcgcca ttcggtccca atccgtccaa ttgtttcaag ccaccataac
     9781 ggctgcccat accggctgcc aataagaata aagttggttt catattagtt attatttaaa
     9841 aaggttagtg tatcacagtt gataacggtt gcaaatgtac aaaaatttat ggctgacaga
     9901 agggagtttt agttcattct ttaccactat ccgttcaaaa acgtacattt agaacggata
     9961 accgatggca aaatgcagtg ccatactatc cttgaactta ggaatattgt aatatcccga
    10021 ctttccggta tcatacgggt cgtgaagccc gatacccaaa tccagacgga aaacaaggaa
    10081 gtccaggtca tagcgtaagc cgaatcccgt acccaaagca atctgtttcg ggaaattctt
    10141 caaggtgaac tcaccgttcg ggcgattttc gtccttacgc atcagccata cattgccggc
    10201 atccagaaac accgctccat gcaagtcggc aatcatacgg aagcgatact cgatattggc
    10261 ttctatgcga atatcaccca cgtggttgat ataggtatat ttcctatccg tctcgggagg
    10321 atagccgccc ggacctatac tgcgtgcaga aaaggcgcgc acactgttgg caccgccgat
    10381 atagaactgt tccgtataag gtgcggtcgt agcgttgcca tacgaccata tcacccctcc
    10441 ggcaatacgc gaggctatca tctgattctt gtctatccgg taatggtacc tgaattccga
    10501 gttcagcttc aggaactgtg caaaaggtac cccgaaaagc ttctttcctt cctcactgaa
    10561 cggcttgccg aaaatacggt agacggcaga agtcaggtta ccggccgacg caacggtggt
    10621 ctgccaccag atggggttac gcttgccgcg cacggaagcg ttgtcataag tataggtgta
    10681 ctccatggca ggaatgaact ggtcgcgcaa actaacgtag agtgccggat tctcggcacg
    10741 caacgtatcg aaagcggcag taggattgcg cagtacattg aatgtcaacc ggaaaggagt
    10801 tatactgtgc ctggaagtcg atttgggctg gaagtcataa gtgacattac cgccaaaagc
    10861 caacagctta taatacttgg cacggttcat ctggtcggca tataaacgga aagtcgttgt
    10921 agccgggaag tcatactcac ggtcgcccat cctaggaaac accacgcgcg gaaagataag
    10981 cgaagtggag atacccagtt cataactgtt catcaaggaa gaacttgcct tgcccgtctg
    11041 ccattcgtac gaaccgttca acttcacatt ccagctttca ccgccaccga agacattgtt
    11101 cttcgtcacc gtaaaagcgg cacccggtcc cgtctggtta ttgctcttca tggtgacatt
    11161 aaaatccaac tccgcatcgt agggtttatc gagcgcggca atgaccctca catccaatgt
    11221 atcagacaca aacgccgtat cacgcggtat atactgcatc tccgcataac ggaaaatacc
    11281 gacgcttgcc agacgctcct gaatacgggt ctgacggtac aaactataca aactctgcat
    11341 agaacgctgg cgggcaatac ctgcgctgtc ctgtatctga cgtttccgcc gataaccttg
    11401 atagttcaac caacggtaaa gcatgttggg acgtaccgga ggtttgttgt agtaatgtat
    11461 ggtcaagcct ttgtaatcca tgctgtcatt gggttcctgc ccctgctttc caagaagata
    11521 gacggattta cgccccacac ggaactgctt ctcggctacc tttggcatac cgggaacggg
    11581 aatcaagcgc atctggacat gcccattggg aaccatcatg gtatcggcct gataggtcag
    11641 gtagtcggga cggaaataat aacagcccac attacgcagc agggtactga tacgggtacg
    11701 ctccccatcc aaatcagcca cattgaattg ttctcccgaa ctgataaggg aacgtcggcg
    11761 tcccagctcc ataatgcgag tggtacgctc gctgaaacca cgataatata ccgtatctat
    11821 aaagtagggg ttacgcatgt tcaccgtata ttgcaacttt gccttcagcg agtccttcgg
    11881 gtcgataaat gtcttgtagc tgacgcttcc gttgaaatag ccataatcgc gcagcaagtt
    11941 aaccgccgcc ttctggcgta tatcgggatt caccgtagac ataagcaccg gagtggcggc
    12001 aaatttattg aatatccact ttccgaatcc cttctcatac ttctggaaac cattgtaaat
    12061 ccacagtccg aaaggaaagg gatagcggat agtagagctt cccagcaacg aattgttcgg
    12121 tgccgtagca agggcggctt ccacctcttc catagcaatc tcaccaacag acgtttcact
    12181 gcggttcaat acaatcatcg gcttttggcc ggtatagagt atctccccct cgggcaagtg
    12241 cttcgtggtg gagcaacctg ccagaaatat caatcctgca atatataata tcagtcgttt
    12301 catatcacat tcctactttt tcatatcgct attttcagcc tccggtttta tctttttctt
    12361 cctgaagatg aagagttcac tcaatcggtc catcttccgg cgcagcacaa ggccgacacc
    12421 cgtttcggtt atctcaccgt cgagtatgct ttcgtagttt ttattatgga atacacggac
    12481 atatcgagta cccgacgcat caagacggta ttccagcgat atattgtcaa tgaatgattc
    12541 cgcatcgttc gtggcattgg ccccggtgga cacttttcca ccgatgacta tctgtacgcg
    12601 gtcgttgaag aaacgctggg aataacgaaa actgaagtct ttctgcgtgt cacccgtttc
    12661 agcagaggta cggtcttcca cacctacact gatattagca ccttttatac ctcccgccaa
    12721 ggagtttatc tggctctgaa gcactgagtt caaggcagct cccattgaca aacctcctcc
    12781 tttggcacca ctgttcaagt aaatacccgt ggcaagcatg gcaatggcct gcttgctacg
    12841 ctcttctgca cccattgcct gcagctcatt ctctactgcg gcatcttcgg gcgccgaaat
    12901 atcgaatatc aaatcgggag cgtcaagcct gttcttgatg gaaatggaaa catcgaagtt
    12961 caccatgcgc gaaccgtccc cgtcaccatc ggccacagaa gcacgcatac gttccgtagc
    13021 ctttaggctc agcgtaggat tcataatatt cccccgccaa tccacataac tgccgggatt
    13081 gaactggaac tccttcaacg ggatgatagg cagcgaatat ttcatgacgc cacccgaaag
    13141 ggtatagcgt ccggtaaggc tcatatcccc ttggggagta tactgcatat tcaaatcacc
    13201 gccaccttcc agttcgatgt atttgctgcg gtcgggactc aagtcagcac gaagacggac
    13261 agcatcgtca atatggacgg acatatacat ttccaatcct cccaaagaca tggcaggaac
    13321 ctcatccgct tttaccgacg tcgtatcggt gaacgaggta aaggtaacca gcccgctgag
    13381 acggtcttcc accgttaaag gggaatcggt caacacgtag gttacgttgg tattgcccag
    13441 caaattcatg tttccacgca tcgtgagccc gtcaagcggc cccttcaccg tggcatgcaa
    13501 gtcgacgaac acctttccat acaccagact ttcgcgggta cgcggtgcat ccagcaacgt
    13561 atagttctct gccagtagat tgaggttggc agtaggacgc tccatattcc ggaaatcaac
    13621 cttaccgtca atcgtaaacg gattcttgct ggtggtataa atggcaaact tatcaaatat
    13681 caactgattg tcctttatct gtaccggacg gttgtcgaac cagtaacgtg ctcccgcctg
    13741 gcgtgcatag acagacacac tgtccaaaac aatatcacca tgcatttgag gcttgtccag
    13801 cgaaccataa atataaagcc ctccatcaat atctccggta aaggccaccg tttggtcagg
    13861 gatgaatgca ttggccatct tcaatggaaa atgctcgaaa cgggtggaca cttccagggt
    13921 atcctttccg ttcttctgcg tcaagatacc gtcggcggtc atcacttctt cattatcata
    13981 tgtaaaatag gtattcagat agtgcgtatt cttgtcgccc ggcaaccagg tagcccccag
    14041 gccgatgtct ccaaccggtt ggcgttcgta ggtcagtttc tctacattgg cttcggcgga
    14101 cacctgcagg gaagtggcag tctgtatata atttgcttcg gcggagaaca atcccgtaag
    14161 ccggggcata taaggaagta cctccgtaag ttcatccagg cgcaatcggc tcagttctac
    14221 gtttatattc tgcaaggaaa gggtatcatt cttgtcggat tgcatacgga aacacagacc
    14281 atcgtcgctg tccatatcaa tattggcata gacgcgcata ttcttatgca gataaatcca
    14341 gttactattg tccgcaaagt ggaatttgcg gaaagcgata atcggctcgg caggaataag
    14401 gttcagcagc acaccattac cgcgaccgtg tccttcggtc aacggacggg cattaatacc
    14461 gaatagaaca ccggtctgcc cttttccatt cacataatcc acagtcagtt ctgcatcttc
    14521 attacggact tcacccgtca gtgtgctacg gaacacaaac tgcgggttct tgggaccgtt
    14581 tatgacacca ccttgcaact tcatgcgggc agtatcctgc ttcactgtaa aaaatatcgt
    14641 atcgagctgc aaggagtcca tgcgcaatcc gtgaacagct gtacgtccat tgatgccgac
    14701 ttgcggagta aatccgaagc tcagtttgaa atcattatag gaaataccct ttgcagccag
    14761 gaaatagctg acgggattct ggttaccggc ttccagatgc atgcccgctg aaggaaggac
    14821 ttggcgcaaa gcggcatggt ccaaacgccg ttcatcaatc tgctttgtca ggatagagac
    14881 aaatttatcc gactgttcca tcaacttctt caacgtgctg tgagcgcgga aacgcagatt
    14941 caagtcaccg gcatcaagcc tcaacttgag agaatcatga cgtgcctccg ctcccattgt
    15001 aaaggcaaac gggtgtttca acggtcgggg caccaaaccc agcttatgca gattcacctc
    15061 ttccacattt aaatccaaag cgccatccag atagctgcgg tcaagacgca tatccgcatt
    15121 tccctgcatc ttgagaagga cattatcgct ggcaagacgg acggtagcaa cggatgactt
    15181 gagtccggca tgcacatcta caccggaaat gtcccaatgg ccatactgta gtttttccaa
    15241 ggaggcattc aaagcggcca cagtttttcg tgatgccaca tccacccctt gccccttagc
    15301 ggacatcttt gccgtaagag tatagataga gtccttgggc aggaagtgat gcacctgcaa
    15361 gttgttgatg gcaaggtcgg catggtaggc ttccgtagca agattatagg cggcgtccaa
    15421 attcaaggcg ccttccttct ccttcagttt cagggcggca gtgcactgcg ccccctccat
    15481 accgagacgt gccgcaaggt gcatactgtc cggcacaatg atggagccat cgggagcaat
    15541 gtcagctagt ccggtcagga agttcaagtt ctgcgtatgc atttcgaagt ccatgcttcc
    15601 attgcgtttc acactgtcgg tcaggctcca gaattctcct cccccactca acgaaaaggc
    15661 tccgggcagc tcagccgtaa aacgggaaat ctgcatctgc ttcaggtttc cttccgtacc
    15721 ggcatgaatc accaacggac ggaatggata ggcttccttg aaagcttccg gcaagccacc
    15781 ggcaaaaagc agtacatcct gtttgccgat acgggcattg aaacgggctg tcagacggcc
    15841 ggtggtaggt atatttatca gttcccagta agtctgtgcc gtaaggttca tctcactatg
    15901 aggtgtcagc aacttcaaag aagggatacg gataacggta gaatcggcaa acaaccgccc
    15961 ggtcagggaa gttacactca aaccggaacg ctcatacatg ga
//
