GCA_001404735.1 - 14 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaBJAINHAM_6 (original name was: gnl|Prokka|BJAINHAM_6)

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	NRPS	96,197	141,632	dipeptide aldehydes	NRP	70%

gnlProkkaBJAINHAM_20 (original name was: gnl|Prokka|BJAINHAM_20)

Region	Type	From	To	Most similar known cluster		Similarity
Region 20.1	lanthipeptide-class-ii,ranthipeptide	1	48,825	ruminococcin A	RiPP:Lanthipeptide	14%

gnlProkkaBJAINHAM_21 (original name was: gnl|Prokka|BJAINHAM_21)

Region	Type	From	To	Most similar known cluster		Similarity
Region 21.1	RRE-containing,cyclic-lactone-autoinducer	1	23,993

gnlProkkaBJAINHAM_28 (original name was: gnl|Prokka|BJAINHAM_28)

Region	Type	From	To	Most similar known cluster		Similarity
Region 28.1	cyclic-lactone-autoinducer	1	24,238

gnlProkkaBJAINHAM_34 (original name was: gnl|Prokka|BJAINHAM_34)

Region	Type	From	To	Most similar known cluster		Similarity
Region 34.1	RRE-containing,cyclic-lactone-autoinducer,lanthipeptide-class-ii	12,156	48,227	ruminococcin A	RiPP:Lanthipeptide	21%

gnlProkkaBJAINHAM_36 (original name was: gnl|Prokka|BJAINHAM_36)

Region	Type	From	To	Most similar known cluster		Similarity
Region 36.1	lanthipeptide-class-ii	21,009	43,783	ruminococcin A	RiPP:Lanthipeptide	42%

gnlProkkaBJAINHAM_41 (original name was: gnl|Prokka|BJAINHAM_41)

Region	Type	From	To	Most similar known cluster		Similarity
Region 41.1	cyclic-lactone-autoinducer	19,121	39,177	ruminococcin A	RiPP:Lanthipeptide	28%

gnlProkkaBJAINHAM_52 (original name was: gnl|Prokka|BJAINHAM_52)

Region	Type	From	To	Most similar known cluster		Similarity
Region 52.1	NRPS	1	29,153

gnlProkkaBJAINHAM_60 (original name was: gnl|Prokka|BJAINHAM_60)

Region	Type	From	To	Most similar known cluster		Similarity
Region 60.1	ranthipeptide	1	18,910

gnlProkkaBJAINHAM_69 (original name was: gnl|Prokka|BJAINHAM_69)

Region	Type	From	To	Most similar known cluster		Similarity
Region 69.1	cyclic-lactone-autoinducer	1	16,388

gnlProkkaBJAINHAM_74 (original name was: gnl|Prokka|BJAINHAM_74)

Region	Type	From	To	Most similar known cluster		Similarity
Region 74.1	RRE-containing	2,440	17,387

gnlProkkaBJAINHAM_79 (original name was: gnl|Prokka|BJAINHAM_79)

Region	Type	From	To	Most similar known cluster		Similarity
Region 79.1	ranthipeptide	1	15,239

gnlProkkaBJAINHAM_101 (original name was: gnl|Prokka|BJAINHAM_101)

Region	Type	From	To	Most similar known cluster		Similarity
Region 101.1	cyclic-lactone-autoinducer	1	7,503

gnlProkkaBJAINHAM_108 (original name was: gnl|Prokka|BJAINHAM_108)

Region	Type	From	To	Most similar known cluster		Similarity
Region 108.1	cyclic-lactone-autoinducer	1	5,798

Compact view

gnlProkkaBJAINHAM_6 - Region 1 - NRPS

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Location: 96,197 - 141,632 nt. (total: 45,436 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 96196 - 141632:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg6_105

AMP-binding (20..419): X

nrpys: Leu, Trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVLTDGGISK
Nearest Stachelhaus code(s):: Leu or Trp DVLTDGGISK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1033..1421): X

nrpys: Leu, Trp

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAMFSGAIFK
Nearest Stachelhaus code(s):: Leu or Trp DAMFSGAIFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (2027..2418): X

nrpys: Leu, Trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAITTGGVSK
Nearest Stachelhaus code(s):: Leu or Trp DAITTGGVSK (97% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaBJAINHAM_20 - Region 1 - lanthipeptide-class-ii,ranthipeptide

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Location: 1 - 48,825 nt. (total: 48,825 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

Lanthipeptide predictions

Lanthipeptide(s) for ctg20_4

ctg20_5

Leader:

MKKNYRNPMTRPENFMNPAGNVMKEIKEADLNNFSAGAGEPRVSDGS

Core:

QFCTSTKECNWGTIMFVCC

Core with dehydrations:

QFCysDhbDhaDhbKECysNWGDhbIMFVCysCys

MIBiG 3.1 matches for ctg20_5

26.3% BGC0000503 (cinA): Lanthipeptide: cinnamycin

7

KECNWGTIMFVC

18

+ C++G FVC

3

QSCSFGPFTFVC

14

20.0% BGC0002110 (QKV49893.1): Lanthipeptide: birimositide

2

FCTSTKEC

9

+CT TKEC

18

WCTLTKEC

25

17.9% BGC0000517 (BAB04173.1): Lanthipeptide: haloduracin β or haloduracin α

2

FCTSTKEC

9

+CT T EC

16

YCTLTVEC

23

with 3 more sequence matches

13.6% BGC0000553 (SSGG_RS09925): Lanthipeptide: SRO15-2212

9

CNWGTIMFVCC

19

C + ++ V C

10

CEYSSLSVVLC

20

12.8% BGC0001229 (SBI_06990): Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

3

CTSTKEC

9

CT +KEC

28

CTLSKEC

34

10.8% BGC0001229 (SBI_06989)and 1 other:

BGC0002110 (QKV49894.1) Lanthipeptide: birimositide

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

2

FCTSTK

7

FC +TK

27

FCPTTK

32

antiSMASH-DB 4.0 matches for ctg20_5

100.0% NZ_CP102267.1and 11 others:

NZ_FMUW01000051.1 Lanthipeptides: BLP57_RS16830_lanthipeptideNZ_JAQDBP010000004.1 Lanthipeptides: PGY07_RS07130_lanthipeptideNZ_JAQEHQ010000024.1 Lanthipeptides: PGR68_RS13915_lanthipeptideNZ_JAQESL010000043.1 Lanthipeptides: PG840_RS15980_lanthipeptideNZ_JAQESS010000001.1 Lanthipeptides: PG808_RS00050_lanthipeptideNZ_LN913006.1 Lanthipeptides: BN3261_RS01470_lanthipeptideNZ_QRPQ01000011.1 Lanthipeptides: DWZ74_RS14610_lanthipeptideNZ_QRZZ01000003.1 Lanthipeptides: DWV87_RS03120_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: DW767_RS16305_lanthipeptideNZ_QSKF01000004.1 Lanthipeptides: DW740_RS06255_lanthipeptideNZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03580_lanthipeptide

Lanthipeptides: NQ550_RS04155_lanthipeptide

1

QFCTSTKECNWGTIMFVCC

19

QFCTSTKECNWGTIMFVCC

1

QFCTSTKECNWGTIMFVCC

19

42.9% NZ_QRHZ01000008.1and 2 others:

NZ_QSRF01000021.1 Lanthipeptides: DXC87_RS15310_lanthipeptideNZ_QUEQ01000033.1 Lanthipeptides: DXA48_RS19000_lanthipeptide

Lanthipeptides: DW272_RS13830_lanthipeptide

2

FCTSTKECNWGTIMFVCC

19

FCTST ECN GT+ CC

11

FCTSTGECNMGTLNIFCC

28

40.0% NZ_JAFCGV010000005.1: Lanthipeptides: JQI09_RS04275_lanthipeptide

4

TSTKECNWGTIMFVCC

19

T+T EC GT FVCC

7

TATSECYLGTFAFVCC

22

with 18 more sequence matches

40.0% NZ_WBPF01000002.1: Lanthipeptides: F8162_RS00195_lanthipeptide

1

QFCTSTKECNWGT--IMFVCC

19

QF T + EC+W T +F CC

4

QFDTISHECHWNTWQFLFTCC

24

36.0% NZ_CP045267.1and 1 other:

NZ_CP045267.1 Lanthipeptides: FDZ14_RS00155_lanthipeptide

Lanthipeptides: FDZ14_RS00155_lanthipeptide

4

TSTKECNWGTIMFVCC

19

T+T EC GT F CC

7

TATSECYLGTFAFACC

22

34.6% NZ_CP117876.1: Lanthipeptides: PQ460_RS01735_lanthipeptide

4

TSTKECNWGTIMFVCC

19

T+T EC GT+ F+CC

7

TATSECYLGTVAFICC

22

33.3% NZ_CYXV01000003.1: Lanthipeptides: ARB75_RS04585_lanthipeptide

3

CTSTKECNWGTIMFVCC

19

CT T ECN GT + CC

12

CTLTGECNIGTHIKFCC

28

29.2% NC_012470.1and 42 others:

NZ_CAAHGW010000010.1 Lanthipeptides: E9435_RS08895_lanthipeptideNZ_CAAHHE010000002.1 Lanthipeptides: E9499_RS02930_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08675_lanthipeptideNZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05705_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08735_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08985_lanthipeptideNZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01075_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09255_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08770_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08920_lanthipeptideNZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02160_lanthipeptideNZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09650_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03445_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08815_lanthipeptideNZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03175_lanthipeptideNZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02475_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08475_lanthipeptideNZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09585_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09025_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08485_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08495_lanthipeptideNZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS10120_lanthipeptideNZ_CP018188.1 Lanthipeptides: BSR19_RS11185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05190_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02600_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06670_lanthipeptideNZ_CP035443.1 Lanthipeptides: ETT56_RS07260_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07305_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09825_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05340_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09695_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS10860_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05070_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06745_lanthipeptideNZ_NWMU01000024.1 Lanthipeptides: CO197_RS09155_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04325_lanthipeptideNZ_VMMF01000004.1 Lanthipeptides: HT717_RS01580_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05570_lanthipeptide

Lanthipeptides: SZO_RS10260_lanthipeptide

4

TSTKECNWGTI--MFVCC

19

T + EC W ++ +F CC

7

TISAECRWNSLQAIFTCC

24

29.2% NZ_ALSD01000046.1and 5 others:

NZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06795_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS10995_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS1000000113590_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03150_lanthipeptideNZ_LT545678.1 Lanthipeptides: BJR96_RS11590_lanthipeptide

Lanthipeptides: SAG0161_RS1000000124770_lanthipeptide

4

TSTKECNWGTI--MFVCC

19

T + EC W ++ +F CC

7

TISAECRWNSLQAIFSCC

24

27.6% NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06310_lanthipeptide

Lanthipeptides: EG886_RS06310_lanthipeptide

1

QFCTSTKEC

9

QFCT TKEC

15

QFCTLTKEC

23

26.3% NZ_CP059557.1: Lanthipeptides: H2Q94_RS19875_lanthipeptide

7

KECNWGTIMFVC

18

+ C+WG + VC

3

QSCSWGPVTAVC

14

25.0% NC_021362.1and 29 others:

NC_021362.1 Lanthipeptides: BALI_RS00925_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptide

Lanthipeptides: BALI_RS00925_lanthipeptide

1

QFCTSTKEC

9

Q+CT TKEC

15

QWCTLTKEC

23

24.1% NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06305_lanthipeptide

Lanthipeptides: EG886_RS06305_lanthipeptide

1

QFCTSTKEC

9

+FCT TKEC

15

RFCTLTKEC

23

21.6% NZ_CP016767.1: Lanthipeptides: BCV50_RS18735_lanthipeptide

1

QFCTSTKECNWGTI

14

Q+CT + EC +GTI

21

QYCTVSAEC-FGTI

33

20.6% NZ_JAESIP010000017.1and 3 others:

NZ_LT907978.1 Lanthipeptides: EHLA_RS12685_lanthipeptideNZ_QRYY01000029.1 Lanthipeptides: DWW21_RS18370_lanthipeptideNZ_SPFW01000044.1 Lanthipeptides: FGQ81_RS16590_lanthipeptide

Lanthipeptides: JMK14_RS12260_lanthipeptide

1

QFCTSTKECNWGTIM

15

+ CT T EC TI+

18

RLCTGTAECPIMTII

32

19.2% NZ_CZAY01000009.1and 12 others:

NZ_CZBA01000009.1 Lanthipeptides: ARA06_RS08755_lanthipeptideNZ_CZBB01000003.1 Lanthipeptides: ARA29_RS04330_lanthipeptideNZ_JADPDU010000003.1 Lanthipeptides: I4V06_RS02990_lanthipeptideNZ_JAOQJU010000001.1 Lanthipeptides: OCV99_RS00835_lanthipeptideNZ_JAQCSY010000025.1 Lanthipeptides: PGZ10_RS13865_lanthipeptideNZ_JAQEDC010000020.1 Lanthipeptides: PHA23_RS12680_lanthipeptideNZ_QRZZ01000001.1 Lanthipeptides: DWV87_RS01465_lanthipeptideNZ_QSUB01000001.1 Lanthipeptides: DXB81_RS03120_lanthipeptideNZ_QUCI01000019.1 Lanthipeptides: DW648_RS14740_lanthipeptideNZ_QULD01000003.1 Lanthipeptides: DXB83_RS07060_lanthipeptideNZ_QULI01000007.1 Lanthipeptides: DXB71_RS08970_lanthipeptideNZ_SLZV01000043.1 Lanthipeptides: EDD74_RS14380_lanthipeptide

Lanthipeptides: ARA07_RS06830_lanthipeptide

2

FCTSTKECNWGTIMFVCC

19

CTST EC +GT++ CC

32

LCTSTAECYFGTLLKPCC

49

17.5% NZ_CM001792.1and 1 other:

NZ_CM001792.1 Lanthipeptides: C794_RS17980_lanthipeptide

Lanthipeptides: C794_RS17980_lanthipeptide

2

FCTSTKEC

9

FCT TKEC

26

FCTITKEC

33

17.1% NZ_FQZK01000006.1and 2 others:

NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13060_lanthipeptideNZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13060_lanthipeptide

Lanthipeptides: BUE45_RS13060_lanthipeptide

1

QFCTSTKECN

10

+FCT T ECN

26

RFCTVTVECN

35

16.7% NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21845_lanthipeptide

Lanthipeptides: CN325_RS21845_lanthipeptide

1

QFCTSTKEC

9

++CT++KEC

16

KYCTASKEC

24

15.8% NZ_BMRY01000003.1and 28 others:

NZ_BMRY01000003.1 Lanthipeptides: IE140_RS12370_lanthipeptideNZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12780_lanthipeptideNZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12780_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05285_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05285_lanthipeptideNZ_CP021707.1 Lanthipeptides: CCZ36_RS18205_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19425_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19425_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34965_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34965_lanthipeptideNZ_CP116355.1 Lanthipeptides: KPP03845_RS17815_lanthipeptideNZ_CP116355.1 Lanthipeptides: KPP03845_RS17815_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11020_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11020_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32880_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32880_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS38630_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS38630_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100145_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100145_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18455_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18455_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19720_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19720_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03735_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03735_lanthipeptideNZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29300_lanthipeptideNZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29300_lanthipeptide

Lanthipeptides: IE140_RS12370_lanthipeptide

1

QFCTSTKEC

9

FCT+T EC

25

NFCTATAEC

33

14.7% NZ_CAKMMP010000011.1and 5 others:

NZ_CP018620.1 Lanthipeptides: BS614_RS05680_lanthipeptideNZ_CP062165.1 Lanthipeptides: JNUCC31_RS16755_lanthipeptideNZ_FMVM01000006.1 Lanthipeptides: BLQ13_RS10365_lanthipeptideNZ_RIAS01000010.1 Lanthipeptides: EC604_RS18225_lanthipeptideNZ_VEJI01000010.1 Lanthipeptides: FS576_RS22075_lanthipeptide

Lanthipeptides: L6H98_RS19925_lanthipeptide

2

FCTSTKECNWGTI

14

FCT + EC++ ++

13

FCTVSHECHYNSV

25

ctg20_14

Leader:

MRVVNPMGRKIDTSVEANNIARG

Core:

CTCGTWSNYSGTRTTSDSCSHCGCNCRDASGETTKYSTNNYKDASTAGRKSPVAY

Core with dehydrations:

CysDhbCysGDhbWDhaNYDhaGDhbRDhbDhbDhaDDhaCysDhaHCysGCysNCysRDADhaGEDhbDhbKYDhaDhbNNYKDADhaDhbAGRKDhaPVAY

antiSMASH-DB 4.0 matches for ctg20_14

20.0% NZ_CP110813.1: Lanthipeptides: allorf_3260520_3260750_lanthipeptide

23

GCNCRDASGETTKYSTNNYKDASTA-GRKSP

52

GC C A+G+ T + ++AS A G+ P

4

GCLCGTAAGDRTHRAQLGIRNASDAVGQHRP

34

12.7% NZ_CP119804.1: Lanthipeptides: allorf_1911237_1911419_lanthipeptide

12

TRTTSDSCSHCGCNC

26

R C HC CNC

14

LRLGIVVCGHCTCNC

28

allorf_10945_11043

Leader:

MIRSSIIFFVLNKLQGS

Core:

CQVSVRFLSEKYIIL

Core with dehydrations:

CysQVDhaVRFLDhaEKYIIL

antiSMASH-DB 4.0 matches for allorf_10945_11043

100.0% NZ_CP102267.1and 7 others:

NZ_JAQDBP010000004.1 Lanthipeptides: allorf_177044_177142_lanthipeptideNZ_JAQEHQ010000024.1 Lanthipeptides: allorf_20164_20253_lanthipeptideNZ_JAQESL010000043.1 Lanthipeptides: allorf_02084_02182_lanthipeptideNZ_JAQESS010000001.1 Lanthipeptides: allorf_017059_017148_lanthipeptideNZ_LN913006.1 Lanthipeptides: allorf_0097924_0098022_lanthipeptideNZ_QRPQ01000011.1 Lanthipeptides: allorf_103379_103477_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: allorf_092199_092297_lanthipeptide

Lanthipeptides: allorf_0889319_0889417_lanthipeptide

1

CQVSVRFLSEKYIIL

15

CQVSVRFLSEKYIIL

1

CQVSVRFLSEKYIIL

15

allorf_13096_13251

Leader:

MMLYTYNEFCLIILVMMPTA

Core:

TFRSSSIWSQQRTPYLSSQRCGCRSDCEQWR

Core with dehydrations:

DhbFRDhaDhaDhaIWDhaQQRDhbPYLDhaDhaQRCysGCysRDhaDCysEQWR

antiSMASH-DB 4.0 matches for allorf_13096_13251

19.4% NZ_CP072384.1: Lanthipeptides: allorf_0332557_0332658_lanthipeptide

16

LSSQRCGCRSDCEQWR

31

+S+ G S C +WR

5

MSAPSVGAASTCTRWR

20

13.5% NZ_CM001792.1and 1 other:

NZ_CM001792.1 Lanthipeptides: C794_RS17975_lanthipeptide

Lanthipeptides: C794_RS17975_lanthipeptide

22

GCRSDCEQW

30

C SDC +W

29

ACTSDCTEW

37

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg20_5 - Class II

Cleavage pHMM score: -6.40

RODEO score: 0

Monoisotopic mass: 2127.9 Da

Molecular weight: 2129.5 Da

Number of bridges: 4

ctg20_14 - Class II

Cleavage pHMM score: -3.70

RODEO score: 0

Monoisotopic mass: 5528.4 Da

Molecular weight: 5531.9 Da

Number of bridges: 6

Alternative weights: (assuming N unmodified Ser/Thr residues); 5549.9 Da N = 1; 5567.9 Da N = 2; 5585.9 Da N = 3; 5603.9 Da N = 4; 5622.0 Da N = 5; 5640.0 Da N = 6; 5658.0 Da N = 7; 5676.0 Da N = 8; 5694.0 Da N = 9; 5712.1 Da N = 10; 5730.1 Da N = 11; 5748.1 Da N = 12

allorf_10945_11043 - Class II

Cleavage pHMM score: -5.20

RODEO score: 0

Monoisotopic mass: 1761.0 Da

Molecular weight: 1762.1 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1780.1 Da N = 1

allorf_13096_13251 - Class II

Cleavage pHMM score: -4.80

RODEO score: 0

Monoisotopic mass: 3575.7 Da

Molecular weight: 3577.9 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3595.9 Da N = 1; 3613.9 Da N = 2; 3632.0 Da N = 3; 3650.0 Da N = 4; 3668.0 Da N = 5; 3686.0 Da N = 6

gnlProkkaBJAINHAM_21 - Region 1 - RRE-containing,cyclic-lactone-autoinducer

Download region GenBank file

Download region SVG

Location: 1 - 23,993 nt. (total: 23,993 nt) Show pHMM detection rules used

Region on contig edge.

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaBJAINHAM_28 - Region 1 - cyclic-lactone-autoinducer

Download region GenBank file

Download region SVG

Location: 1 - 24,238 nt. (total: 24,238 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaBJAINHAM_34 - Region 1 - RRE-containing,cyclic-lactone-autoinducer,lanthipeptide-class-ii

Download region GenBank file

Download region SVG

Location: 12,156 - 48,227 nt. (total: 36,072 nt) Show pHMM detection rules used

Region on contig edge.

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

Lanthipeptide predictions

Lanthipeptide(s) for ctg34_50

ctg34_51

Leader:

MSEMRNPITREENFS

Core:

NPAGNVMMELQEADLNKFVAGAGETRNSGGVLCTSTAECYFGTLLKPCCPKK

Core with dehydrations:

NPAGNVMMELQEADLNKFVAGAGEDhbRNDhaGGVLCysDhbDhaDhbAECysYFGDhbLLKPCysCysPKK

MIBiG 3.1 matches for ctg34_51

15.4% BGC0002110 (QKV49893.1): Lanthipeptide: birimositide

27

NSGGVLCTSTAEC

39

N+GG CT T EC

14

NNGG-WCTLTKEC

25

11.5% BGC0000517 (BAB04173.1): Lanthipeptide: haloduracin β or haloduracin α

30

GVLCTSTAEC

39

G CT T EC

14

GAYCTLTVEC

23

7.7% BGC0001229 (SBI_06990): Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

33

CTSTAEC

39

CT + EC

28

CTLSKEC

34

antiSMASH-DB 4.0 matches for ctg34_51

100.0% NZ_CZAY01000009.1and 12 others:

NZ_CZBA01000009.1 Lanthipeptides: ARA06_RS08755_lanthipeptideNZ_CZBB01000003.1 Lanthipeptides: ARA29_RS04330_lanthipeptideNZ_JADPDU010000003.1 Lanthipeptides: I4V06_RS02990_lanthipeptideNZ_JAOQJU010000001.1 Lanthipeptides: OCV99_RS00835_lanthipeptideNZ_JAQCSY010000025.1 Lanthipeptides: PGZ10_RS13865_lanthipeptideNZ_JAQEDC010000020.1 Lanthipeptides: PHA23_RS12680_lanthipeptideNZ_QRZZ01000001.1 Lanthipeptides: DWV87_RS01465_lanthipeptideNZ_QSUB01000001.1 Lanthipeptides: DXB81_RS03120_lanthipeptideNZ_QUCI01000019.1 Lanthipeptides: DW648_RS14740_lanthipeptideNZ_QULD01000003.1 Lanthipeptides: DXB83_RS07060_lanthipeptideNZ_QULI01000007.1 Lanthipeptides: DXB71_RS08970_lanthipeptideNZ_SLZV01000043.1 Lanthipeptides: EDD74_RS14380_lanthipeptide

Lanthipeptides: ARA07_RS06830_lanthipeptide

1

NPAGNVMMELQEADLNKFVAGAGETRNSGGVLCTSTAECYFGTLLKPCCPKK

52

NPAGNVMMELQEADLNKFVAGAGETRNSGGVLCTSTAECYFGTLLKPCCPKK

1

NPAGNVMMELQEADLNKFVAGAGETRNSGGVLCTSTAECYFGTLLKPCCPKK

52

36.5% NZ_QRHZ01000008.1and 2 others:

NZ_QSRF01000021.1 Lanthipeptides: DXC87_RS15310_lanthipeptideNZ_QUEQ01000033.1 Lanthipeptides: DXA48_RS19000_lanthipeptide

Lanthipeptides: DW272_RS13830_lanthipeptide

22

AGETRNSGGVLCTSTAECYFGTLLKPCC

49

AGE RNSGG+ CTST EC GTL CC

1

AGEPRNSGGMFCTSTGECNMGTLNIFCC

28

32.7% NZ_CYXV01000003.1: Lanthipeptides: ARB75_RS04585_lanthipeptide

22

AGETRNSGGVLCTSTAECYFGTLLKPCC

49

AG RNSGG+ CT T EC GT +K CC

1

AGVARNSGGIACTLTGECNIGTHIKFCC

28

with 44 more sequence matches

25.0% NZ_CP071875.1: Lanthipeptides: J4I02_RS02880_lanthipeptide

23

GETRNSGGVLCTSTAECYFGTLLKPCC

49

G +SGG +CT T EC GT CC

2

GIPNHSGGAICTLTHEC-AGTHWYSCC

27

21.2% NC_009480.1and 10 others:

NZ_CP033724.1 Lanthipeptides: EFE39_RS10220_lanthipeptideNZ_CP047051.1 Lanthipeptides: GRD74_RS10365_lanthipeptideNZ_CP047054.1 Lanthipeptides: GRD61_RS10460_lanthipeptideNZ_CP053860.1 Lanthipeptides: DQP62_RS10825_lanthipeptideNZ_CP076352.1 Lanthipeptides: KN218_RS09900_lanthipeptideNZ_CP085137.1 Lanthipeptides: LHJ48_RS10290_lanthipeptideNZ_CP085140.1 Lanthipeptides: LHJ47_RS10305_lanthipeptideNZ_CP095274.1 Lanthipeptides: MU580_RS10460_lanthipeptideNZ_PSTW01000024.1 Lanthipeptides: C5C03_RS09675_lanthipeptideNZ_SISU01000002.1 Lanthipeptides: EOG37_RS09890_lanthipeptide

Lanthipeptides: CMM_RS10575_lanthipeptide

27

NSGGVLCTSTAECYFGTLLKPC

48

+S G LCT T EC GT++ C

1

SSSGWLCTLTIEC--GTIICAC

20

21.2% NZ_CP036455.1and 1 other:

NZ_JAODUN010000003.1 Lanthipeptides: BXY51_RS10560_lanthipeptide

Lanthipeptides: EKD16_RS25235_lanthipeptide

28

SGGVLCTSTAECYFGTLLKPC

48

S G +CT T EC GTL+ C

1

SSGWVCTLTIEC--GTLVCAC

19

21.2% NZ_CP045267.1and 1 other:

NZ_CP045267.1 Lanthipeptides: FDZ14_RS00155_lanthipeptide

Lanthipeptides: FDZ14_RS00155_lanthipeptide

30

GVLCTSTAECYFGTLLKPCCPKK

52

GV+ T+T+ECY GT CC +

3

GVVKTATSECYLGTFAFACCLAR

25

21.2% NZ_CP061274.1and 1 other:

NZ_JADKRR010000001.1 Lanthipeptides: ITJ40_RS10085_lanthipeptide

Lanthipeptides: H9X71_RS09850_lanthipeptide

28

SGGVLCTSTAECYFGTLLKPC

48

S G LCT T EC GT + C

2

SSGWLCTLTIEC--GTFICAC

20

21.2% NZ_CP117876.1: Lanthipeptides: PQ460_RS01735_lanthipeptide

30

GVLCTSTAECYFGTLLKPCCPKK

52

GV+ T+T+ECY GT+ CC +

3

GVVKTATSECYLGTVAFICCLGR

25

21.2% NZ_FQZK01000006.1and 2 others:

NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13060_lanthipeptideNZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13060_lanthipeptide

Lanthipeptides: BUE45_RS13060_lanthipeptide

16

NKFVAGAGETRNSGGVLCTSTAEC

39

N +A A +RN+ G CT T EC

11

NPLIACALLSRNNTGRFCTVTVEC

34

21.2% NZ_JAFCGV010000005.1: Lanthipeptides: JQI09_RS04275_lanthipeptide

30

GVLCTSTAECYFGTLLKPCCPKK

52

GV+ T+T+ECY GT CC +

3

GVVKTATSECYLGTFAFVCCLAR

25

21.2% NZ_NTSR01000029.1and 1 other:

NZ_NTSR01000029.1 Lanthipeptides: CN358_RS25180_lanthipeptide

Lanthipeptides: CN358_RS25180_lanthipeptide

9

ELQEADLNKFVAGAGETRNSGGVLCTSTAEC

39

AD K G G G +CT T EC

10

SFNSADYIKLSIGLGNN----GYICTYTVEC

36

19.2% NZ_AUBN01000022.1: Lanthipeptides: G448_RS16025_lanthipeptide

28

SGGVLCTSTAECYFGTLLKPC

48

S G CT T EC GT + C

2

SSGWFCTLTIEC--GTFICAC

20

19.2% NZ_CAKMMP010000011.1: Lanthipeptides: L6H98_RS19925_lanthipeptide

21

GAGETRNSGGVLCTSTAECYFGTL

44

A E SGGV CT + EC++ ++

2

AAIEAAKSGGVFCTVSHECHYNSV

25

19.2% NZ_CP016767.1: Lanthipeptides: BCV50_RS18735_lanthipeptide

27

NSGGVLCTSTAECYFGTL

44

N+ G CT +AEC FGT+

17

NNYGQYCTVSAEC-FGTI

33

19.2% NZ_CP028130.1: Lanthipeptides: C7V51_RS14690_lanthipeptide

28

SGGVLCTSTAECYFGTLLKPC

48

S G +CT T EC GT++ C

2

SSGWMCTLTIEC--GTIICAC

20

19.2% NZ_CP083176.1and 4 others:

NZ_JABUHD010000002.1 Lanthipeptides: HRR08_RS05415_lanthipeptideNZ_LSLF01000001.1 Lanthipeptides: AXE72_RS04025_lanthipeptideNZ_PNHB01000001.1 Lanthipeptides: CJ210_RS02800_lanthipeptideNZ_QJVA01000001.1 Lanthipeptides: D0T19_RS02755_lanthipeptide

Lanthipeptides: K9E37_RS06280_lanthipeptide

30

GVLCTSTAECYFGT--LLKPCC

49

GV+ T T EC+ T L CC

3

GVMHTLTHECHMNTWQFLLTCC

24

19.2% NZ_CP102267.1and 11 others:

NZ_FMUW01000051.1 Lanthipeptides: BLP57_RS16830_lanthipeptideNZ_JAQDBP010000004.1 Lanthipeptides: PGY07_RS07130_lanthipeptideNZ_JAQEHQ010000024.1 Lanthipeptides: PGR68_RS13915_lanthipeptideNZ_JAQESL010000043.1 Lanthipeptides: PG840_RS15980_lanthipeptideNZ_JAQESS010000001.1 Lanthipeptides: PG808_RS00050_lanthipeptideNZ_LN913006.1 Lanthipeptides: BN3261_RS01470_lanthipeptideNZ_QRPQ01000011.1 Lanthipeptides: DWZ74_RS14610_lanthipeptideNZ_QRZZ01000003.1 Lanthipeptides: DWV87_RS03120_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: DW767_RS16305_lanthipeptideNZ_QSKF01000004.1 Lanthipeptides: DW740_RS06255_lanthipeptideNZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03580_lanthipeptide

Lanthipeptides: NQ550_RS04155_lanthipeptide

32

LCTSTAECYFGTLLKPCC

49

CTST EC +GT++ CC

2

FCTSTKECNWGTIMFVCC

19

19.2% NZ_FMVM01000006.1and 2 others:

NZ_RIAS01000010.1 Lanthipeptides: EC604_RS18225_lanthipeptideNZ_VEJI01000010.1 Lanthipeptides: FS576_RS22075_lanthipeptide

Lanthipeptides: BLQ13_RS10365_lanthipeptide

21

GAGETRNSGGVLCTSTAECYFGTL

44

A E + SGGV CT + EC++ ++

2

AAIEDKKSGGVFCTVSHECHYNSV

25

19.2% NZ_GG666304.1: Lanthipeptides: HMPREF0077_RS09155_lanthipeptide

26

RNSGGVLCTSTAECYFGTLL

45

++S G CT T EC F TL+

13

KDSCGHGCTITTECPFATLI

32

19.2% NZ_JAESIP010000017.1and 3 others:

NZ_LT907978.1 Lanthipeptides: EHLA_RS12685_lanthipeptideNZ_QRYY01000029.1 Lanthipeptides: DWW21_RS18370_lanthipeptideNZ_SPFW01000044.1 Lanthipeptides: FGQ81_RS16590_lanthipeptide

Lanthipeptides: JMK14_RS12260_lanthipeptide

28

SGGVLCTSTAECYFGTLL

45

S G LCT TAEC T++

15

SCGRLCTGTAECPIMTII

32

19.2% NZ_JALAMD010000003.1and 1 other:

NZ_JALAMZ010000007.1 Lanthipeptides: MOC43_RS14030_lanthipeptide

Lanthipeptides: MOB22_RS05100_lanthipeptide

27

NSGGVLCTSTAECYFGTL

44

N+ G CT +AEC FGT+

17

NNYGKYCTVSAEC-FGTI

33

17.3% NZ_ALVU02000002.1and 1 other:

NZ_ALVU02000002.1 Lanthipeptides: SYN7509_RS28800_lanthipeptide

Lanthipeptides: SYN7509_RS28800_lanthipeptide

16

NKFVAGAGETRNSGGVLCT

34

KF G E+ NSG + CT

1

RKFTYGGDESCNSGIIACT

19

17.3% NZ_BMRY01000003.1and 28 others:

NZ_BMRY01000003.1 Lanthipeptides: IE140_RS12370_lanthipeptideNZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12780_lanthipeptideNZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12780_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05285_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05285_lanthipeptideNZ_CP021707.1 Lanthipeptides: CCZ36_RS18205_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19425_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19425_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34965_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34965_lanthipeptideNZ_CP116355.1 Lanthipeptides: KPP03845_RS17815_lanthipeptideNZ_CP116355.1 Lanthipeptides: KPP03845_RS17815_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11020_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11020_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32880_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32880_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS38630_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS38630_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100145_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100145_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18455_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18455_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19720_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19720_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03735_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03735_lanthipeptideNZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29300_lanthipeptideNZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29300_lanthipeptide

Lanthipeptides: IE140_RS12370_lanthipeptide

21

GAGETRNSGGVLCTSTAEC

39

GA + G CT+TAEC

15

GASYVLGNNGNFCTATAEC

33

17.3% NZ_CP034669.1: Lanthipeptides: EJ065_RS32040_lanthipeptide

26

RNSGGVLCTSTAEC

39

RNS G +CT T EC

7

RNSCGYVCTLTTEC

20

17.3% NZ_CP040409.1and 4 others:

NZ_CP040411.1 Lanthipeptides: FE334_RS06825_lanthipeptideNZ_CP040422.1 Lanthipeptides: FE323_RS09430_lanthipeptideNZ_JH601103.1 Lanthipeptides: HMPREF9703_RS02710_lanthipeptideNZ_NAQX01000046.1 Lanthipeptides: B8A46_RS06295_lanthipeptide

Lanthipeptides: FE336_RS08590_lanthipeptide

26

RNSGGVLCTSTAEC

39

R+S G CT TAEC

12

RHSCGRACTITAEC

25

17.3% NZ_CP086242.1and 1 other:

NZ_CP086245.1 Lanthipeptides: LL037_RS25615_lanthipeptide

Lanthipeptides: LL038_RS25355_lanthipeptide

28

SGGVLCTSTAEC-YFGTL

44

S G +CT+T EC YF +

2

SSGAICTATTECTYFSAI

19

17.3% NZ_CP092836.1: Lanthipeptides: MLD62_RS30280_lanthipeptide

14

DLNKFVAGAGETRNSGGVLCTSTAEC

39

+L+ +A A + + G CT +AEC

2

NLSAAIADAAGLKGNYGKFCTYSAEC

27

17.3% NZ_JAENHX010000011.1: Lanthipeptides: JIN86_RS20375_lanthipeptide

15

LNKFVAGAGETRNSGGVLCTSTAEC

39

+++ +A A N+ G+ CT +AEC

7

ISRAIANAVGLGNNYGMACTWSAEC

31

17.3% NZ_QORY01000016.1and 1 other:

NZ_QORY01000016.1 Lanthipeptides: DT250_RS18255_lanthipeptide

Lanthipeptides: DT250_RS18255_lanthipeptide

30

GVLCTSTAECYFGTLLKP

47

G +CT T EC G L P

23

GRICTYTLECTAGCNLNP

40

16.4% NZ_AP023359.1: Lanthipeptides: Prubr_RS34925_lanthipeptide

1

NPAGNVMM--ELQEADLNKFVAGAGET

25

NPAG + + + EAD+ +G G T

13

NPAGPLFLGGKYAEADITATGSGGGAT

39

15.4% NZ_CP018620.1and 1 other:

NZ_CP062165.1 Lanthipeptides: JNUCC31_RS16755_lanthipeptide

Lanthipeptides: BS614_RS05680_lanthipeptide

24

ETRNSGGVLCTSTAECYFGTL

44

+ + SGGV CT + EC++ ++

5

DAQASGGVFCTVSHECHYNSV

25

15.4% NZ_CP022163.1: Lanthipeptides: MEBOL_RS24465_lanthipeptide

27

NSGGVLCTSTAEC

39

NSGG +CT + EC

10

NSGGWICTYSTEC

22

15.4% NZ_CP030280.1and 5 others:

NZ_CP030280.1 Lanthipeptides: DQQ01_RS07655_lanthipeptideNZ_CP030280.1 Lanthipeptides: DQQ01_RS07650_lanthipeptideNZ_CP030280.1 Lanthipeptides: DQQ01_RS07645_lanthipeptideNZ_CP030280.1 Lanthipeptides: DQQ01_RS07650_lanthipeptideNZ_CP030280.1 Lanthipeptides: DQQ01_RS07645_lanthipeptide

Lanthipeptides: DQQ01_RS07655_lanthipeptide

23

GETRNSG--GVLCTSTAEC

39

G++++ G G LC+ T EC

1

GKSKDWGNDGYLCSVTVEC

19

15.4% NZ_CP034248.1: Lanthipeptides: EIM92_RS14995_lanthipeptide

28

SGGVLCTSTAECYFGTL

44

SGGV+CT + EC++ ++

6

SGGVICTISHECHYNSV

22

15.4% NZ_CP086142.1and 3 others:

NZ_CP086142.1 Lanthipeptides: LL065_RS25460_lanthipeptideNZ_CP086142.1 Lanthipeptides: LL065_RS25455_lanthipeptideNZ_CP086142.1 Lanthipeptides: LL065_RS25450_lanthipeptide

Lanthipeptides: LL065_RS25465_lanthipeptide

29

GGVLCTSTAECYFGTL

44

GGV+ T T ECY+ ++

2

GGVITTFTHECYYNSV

17

15.4% NZ_CP091285.1: Lanthipeptides: L2Z92_RS16370_lanthipeptide

23

GETRNSGGVLCTSTAEC

39

G+TR + G C +TA C

1

GKTRTASGSTCDNTAVC

17

15.4% NZ_CP114875.1: Lanthipeptides: O4Z47_RS14375_lanthipeptide

26

RNSGGVLCTSTAEC

39

+NS G +CT T+EC

5

KNSSGDICTLTSEC

18

15.4% NZ_CP115450.1and 1 other:

NZ_CP115450.1 Lanthipeptides: O1G21_RS35415_lanthipeptide

Lanthipeptides: O1G21_RS35415_lanthipeptide

30

GVLCTSTAEC

39

G LCT TAEC

22

GYLCTVTAEC

31

15.4% NZ_JADPCZ010000011.1and 1 other:

NZ_OW659477.1 Lanthipeptides: NMG62_RS06660_lanthipeptide

Lanthipeptides: I4W03_RS06785_lanthipeptide

26

RNSGGVLCTSTAECYFGTLL

45

++S G CT T EC T++

13

KHSCGRACTVTTECPIATII

32

15.4% NZ_JALMDK010000017.1: Lanthipeptides: allorf_059288_059443_lanthipeptide

28

SGGVLCTSTAEC

39

SGG +CT T EC

2

SGGYICTLTWEC

13

13.5% NZ_BCEY01000006.1and 1 other:

NZ_BCEY01000006.1 Lanthipeptides: GOZ53_RS01290_lanthipeptide

Lanthipeptides: GOZ53_RS01290_lanthipeptide

30

GVLCTSTAEC

39

G +CT TAEC

23

GWICTWTAEC

32

13.5% NZ_CP077726.1and 12 others:

NZ_CP077726.1 Lanthipeptides: KTC92_RS18420_lanthipeptideNZ_CP077726.1 Lanthipeptides: KTC92_RS18415_lanthipeptideNZ_CP077726.1 Lanthipeptides: KTC92_RS18410_lanthipeptideNZ_CP077726.1 Lanthipeptides: KTC92_RS18405_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19070_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19065_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19060_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19055_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19050_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19045_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19040_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19035_lanthipeptide

Lanthipeptides: KTC92_RS18425_lanthipeptide

30

GVLCTSTAECYFGTL

44

GV+ T T ECY+ ++

3

GVITTFTHECYYNSV

17

13.5% NZ_JAQDBP010000004.1and 18 others:

NZ_JAQDBP010000004.1 Lanthipeptides: PGY07_RS07085_lanthipeptideNZ_JAQEAL010000002.1 Lanthipeptides: PGU65_RS02165_lanthipeptideNZ_JAQESL010000010.1 Lanthipeptides: PG840_RS09145_lanthipeptideNZ_JAQEUC010000007.1 Lanthipeptides: PG788_RS06860_lanthipeptideNZ_QRHW01000005.1 Lanthipeptides: DW641_RS05035_lanthipeptideNZ_QROS01000011.1 Lanthipeptides: DW021_RS13630_lanthipeptideNZ_QRPQ01000001.1 Lanthipeptides: DWZ74_RS02490_lanthipeptideNZ_QRZZ01000003.1 Lanthipeptides: DWV87_RS03165_lanthipeptideNZ_QRZZ01000003.1 Lanthipeptides: DWV87_RS03165_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: DW767_RS16350_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: DW767_RS16350_lanthipeptideNZ_QSKF01000004.1 Lanthipeptides: DW740_RS06305_lanthipeptideNZ_QSKF01000004.1 Lanthipeptides: DW740_RS06305_lanthipeptideNZ_QTZB01000014.1 Lanthipeptides: DXC15_RS13895_lanthipeptideNZ_QUCI01000011.1 Lanthipeptides: DW648_RS10830_lanthipeptideNZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03630_lanthipeptideNZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03630_lanthipeptideNZ_QUKU01000006.1 Lanthipeptides: DXC27_RS05470_lanthipeptide

Lanthipeptides: PGY07_RS07085_lanthipeptide

24

ETRNSGGVLCTSTAEC

39

++ S GV+CT + EC

8

DSLASSGVVCTISVEC

23

13.5% NZ_NTSR01000034.1: Lanthipeptides: CN358_RS26370_lanthipeptide

30

GVLCTSTAECYF

41

G +CT +AEC F

20

GTMCTVSAECMF

31

11.5% NZ_VDYW01000008.1: Lanthipeptides: allorf_137107_137307_lanthipeptide

40

YFGTLLKPCCP

50

Y G +L CCP

10

YVGDILLNCCP

20

9.6% NZ_AP018194.1: Lanthipeptides: CA739_RS01285_lanthipeptide

39

CYFGTLLKPC

48

C+ T++KPC

2

CFVSTIIKPC

11

allorf_37153_37251

Leader:

MWKKKYRERGKSQGY

Core:

LKVTSRKSQCSWYIITV

Core with dehydrations:

LKVDhbDhaRKDhaQCysDhaWYIIDhbV

antiSMASH-DB 4.0 matches for allorf_37153_37251

100.0% NZ_CZAY01000009.1and 11 others:

NZ_CZBA01000009.1 Lanthipeptides: allorf_046797_046895_lanthipeptideNZ_CZBB01000003.1 Lanthipeptides: allorf_027211_027309_lanthipeptideNZ_JADPDU010000003.1 Lanthipeptides: allorf_107261_107359_lanthipeptideNZ_JAOQJU010000001.1 Lanthipeptides: allorf_163570_163668_lanthipeptideNZ_JAQCSY010000025.1 Lanthipeptides: allorf_10713_10811_lanthipeptideNZ_JAQEDC010000020.1 Lanthipeptides: allorf_15206_15304_lanthipeptideNZ_QRZZ01000001.1 Lanthipeptides: allorf_316866_316964_lanthipeptideNZ_QSUB01000001.1 Lanthipeptides: allorf_0632573_0632671_lanthipeptideNZ_QUCI01000019.1 Lanthipeptides: allorf_10688_10786_lanthipeptideNZ_QULD01000003.1 Lanthipeptides: allorf_363255_363353_lanthipeptideNZ_QULI01000007.1 Lanthipeptides: allorf_134293_134391_lanthipeptide

Lanthipeptides: allorf_037119_037217_lanthipeptide

1

LKVTSRKSQCSWYIITV

17

LKVTSRKSQCSWYIITV

1

LKVTSRKSQCSWYIITV

17

9.3% NZ_BJTV01000007.1: Lanthipeptides: allorf_023321_023548_lanthipeptide

7

KSQCSWYIIT

16

++ CSWY+ T

29

RTACSWYVRT

38

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg34_51 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 5354.6 Da

Molecular weight: 5358.1 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 5376.2 Da N = 1; 5394.2 Da N = 2

allorf_37153_37251 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 1921.1 Da

Molecular weight: 1922.3 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1940.3 Da N = 1; 1958.3 Da N = 2; 1976.3 Da N = 3; 1994.4 Da N = 4

gnlProkkaBJAINHAM_36 - Region 1 - lanthipeptide-class-ii

Download region GenBank file

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Location: 21,009 - 43,783 nt. (total: 22,775 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

Lanthipeptide predictions

Lanthipeptide(s) for ctg36_29

ctg36_27

Leader:

MKKDIEKMTNPMTEEELEAVLGG

ctg36_28

Leader:

MKKDIEKMTNPMTEEELEAVLGG

Shared core:

GNGIVNTLTHECHVNSWAVTEWFTCCD

Core with dehydrations:

GNGIVNDhbLDhbHECysHVNDhaWAVDhbEWFDhbCysCysD

MIBiG 3.1 matches for ctg36_27

21.4% BGC0000517 (BAB04173.1): Lanthipeptide: haloduracin β or haloduracin α

2

NGIVNTLTHEC

12

G TLT EC

13

KGAYCTLTVEC

23

20.0% BGC0002110 (QKV49893.1): Lanthipeptide: birimositide

7

TLTHECHVN

15

TLT EC N

20

TLTKECQPN

28

antiSMASH-DB 4.0 matches for ctg36_27

59.3% NZ_GL882519.1: Lanthipeptides: HMPREF9056_RS03330_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

GNG+ TL+HECH+NSW FTCC

1

GNGVYYTLSHECHMNSWQFI--FTCCS

25

59.3% NZ_JAEEGA010000010.1: Lanthipeptides: I6N95_RS15660_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEW-FTCCD

27

GNG++ T++HECH+NSW +W FTCC

1

GNGVIKTISHECHMNSW---QWIFTCCS

25

55.6% NZ_CP026729.1: Lanthipeptides: BKKJ1_RS07010_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

GNG+V T++HEC++NSW FTCC

1

GNGVVTTISHECNMNSWQF--LFTCC

24

with 59 more sequence matches

55.6% NZ_CP072384.1: Lanthipeptides: J5A65_RS01395_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

G G+V T+THECH+NSW +WF C

1

GRGVVPTVTHECHMNSW---QWFFGC

23

55.6% NZ_GL985606.1: Lanthipeptides: HMPREF9062_RS00700_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

GNG+ +T++HEC+ NSWA FTCC

1

GNGVFHTISHECYYNSWAFI--FTCC

24

55.6% NZ_MSRJ01000005.1: Lanthipeptides: BKH06_RS03750_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

GNG+ T THEC+ NS+ V FTCC

1

GNGVFYTFTHECNTNSFYVA--FTCCS

25

51.9% NC_012470.1and 2 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06490_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09840_lanthipeptide

Lanthipeptides: SZO_RS04065_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCCD

27

NG + T++HECH+NSW FTCC

3

NGAIKTISHECHMNSWQFL--FTCCS

26

51.9% NC_012470.1and 11 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06485_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05180_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09835_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09830_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05350_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05345_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05065_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05060_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05580_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05575_lanthipeptide

Lanthipeptides: SZO_RS04070_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCCD

27

NG+ T++HECH+NSW FTCC

3

NGVFKTISHECHMNSWQFL--FTCCS

26

51.9% NC_013928.1and 8 others:

NC_013928.1 Lanthipeptides: SMUNN2025_RS01700_lanthipeptideNZ_CP023477.1 Lanthipeptides: CO204_RS01885_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS01090_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS01080_lanthipeptideNZ_CP061071.1 Lanthipeptides: IBL27_RS01745_lanthipeptideNZ_CP061071.1 Lanthipeptides: IBL27_RS01735_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07575_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07565_lanthipeptide

Lanthipeptides: SMUNN2025_RS01710_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

G G V T++HEC NSWA TCC

2

GKGAVGTISHECRYNSWAFLA--TCCS

26

51.9% NC_015760.1and 5 others:

NZ_CAJHJN010000010.1 Lanthipeptides: JMZ68_RS09030_lanthipeptideNZ_JACLQK010000036.1 Lanthipeptides: H7U04_RS11500_lanthipeptideNZ_JADPEB010000003.1 Lanthipeptides: I4U26_RS02800_lanthipeptideNZ_JAQCST010000021.1 Lanthipeptides: PGZ09_RS09470_lanthipeptideNZ_OU540596.1 Lanthipeptides: JQ838_RS05640_lanthipeptide

Lanthipeptides: SALIVB_RS03310_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

GNG+V TLTHEC++ +W T+ CC

1

GNGVVLTLTHECNLATW--TKKLKCC

24

51.9% NZ_AP025017.1: Lanthipeptides: MANAM107_RS05920_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCCD

27

NG++ T++HECH+N+WA FTCC

1

NGVITTISHECHLNTWAFA--FTCCS

24

51.9% NZ_CP018188.1and 17 others:

NZ_CP018188.1 Lanthipeptides: BSR19_RS11175_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07300_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07295_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09705_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09700_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09300_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09295_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09300_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09295_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06585_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06580_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06585_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06580_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05120_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05115_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04335_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04330_lanthipeptide

Lanthipeptides: BSR19_RS11180_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

GNG+ T++HECH+N+WA TCC

1

GNGVFKTISHECHLNTWAFLA--TCCS

25

51.9% NZ_CP023477.1: Lanthipeptides: CO204_RS01875_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

G G V T++HEC NSWA TCC

2

GKGTVGTISHECRYNSWAFLA--TCCS

26

51.9% NZ_CP023483.1: Lanthipeptides: CNY62_RS11970_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

GNG + T++HECH+N+W FTCC

1

GNGAIRTISHECHMNTWQFL--FTCCS

25

51.9% NZ_CP031746.1: Lanthipeptides: DCC27_RS08165_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCCD

27

+G+++TLTHECH+NSW TCC

1

DGVISTLTHECHMNSWQ--GLLTCCS

24

51.9% NZ_CP046629.1and 3 others:

NZ_FNJX01000002.1 Lanthipeptides: BLR40_RS05025_lanthipeptideNZ_FNZS01000001.1 Lanthipeptides: BMX70_RS03125_lanthipeptideNZ_FOLK01000002.1 Lanthipeptides: BM262_RS05670_lanthipeptide

Lanthipeptides: GPA00_RS05740_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

G+G+V T++H+CH+NSW FTCC

3

GSGVVPTVSHDCHMNSWQF--LFTCCS

27

51.9% NZ_CP083176.1and 4 others:

NZ_JABUHD010000002.1 Lanthipeptides: HRR08_RS05415_lanthipeptideNZ_LSLF01000001.1 Lanthipeptides: AXE72_RS04025_lanthipeptideNZ_PNHB01000001.1 Lanthipeptides: CJ210_RS02800_lanthipeptideNZ_QJVA01000001.1 Lanthipeptides: D0T19_RS02755_lanthipeptide

Lanthipeptides: K9E37_RS06280_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

G+G+++TLTHECH+N+W TCC

1

GDGVMHTLTHECHMNTWQF--LLTCC

24

51.9% NZ_JH792236.1and 1 other:

NZ_JH792236.1 Lanthipeptides: IIM_RS26240_lanthipeptide

Lanthipeptides: IIM_RS26245_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

G+G++ T++HECH+NSW FTCC

1

GSGVIKTISHECHMNSWQAI--FTCCS

25

48.1% NZ_ALSD01000046.1and 49 others:

NZ_CAAHGW010000010.1 Lanthipeptides: E9435_RS08890_lanthipeptideNZ_CAAHHE010000002.1 Lanthipeptides: E9499_RS02935_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08685_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08680_lanthipeptideNZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05700_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08730_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08725_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08980_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08975_lanthipeptideNZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01070_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09265_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09260_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08765_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08760_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08915_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08910_lanthipeptideNZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02170_lanthipeptideNZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09655_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03455_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03450_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08825_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08820_lanthipeptideNZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03170_lanthipeptideNZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02470_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08470_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08465_lanthipeptideNZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09580_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09035_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09030_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08495_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08490_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08505_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08500_lanthipeptideNZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06790_lanthipeptideNZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06785_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS04310_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS04305_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02595_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02590_lanthipeptideNZ_CP035428.1 Lanthipeptides: ETT71_RS02815_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06680_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06675_lanthipeptideNZ_CP035443.1 Lanthipeptides: ETT56_RS07265_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS105315_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03145_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03140_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06755_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06750_lanthipeptideNZ_LT545678.1 Lanthipeptides: BJR96_RS07040_lanthipeptide

Lanthipeptides: SAG0161_RS120605_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCCD

27

NG+ T++HECH+N+WA TCC

3

NGVFKTISHECHLNTWAFLA--TCCS

26

48.1% NZ_CP060646.1: Lanthipeptides: H7789_RS06845_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCCD

27

NG+ T++HECH+N+WA TCC

3

NGVFKTISHECHLNTWA--SLATCCS

26

48.1% NZ_CP069183.1: Lanthipeptides: LLNCDO700_RS13730_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

G+G+++T++HEC++NSW FTCC

3

GSGVIHTISHECNMNSWQFV--FTCCS

27

48.1% NZ_CP077726.1and 12 others:

NZ_CP077726.1 Lanthipeptides: KTC92_RS18420_lanthipeptideNZ_CP077726.1 Lanthipeptides: KTC92_RS18415_lanthipeptideNZ_CP077726.1 Lanthipeptides: KTC92_RS18410_lanthipeptideNZ_CP077726.1 Lanthipeptides: KTC92_RS18405_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19070_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19065_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19060_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19055_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19050_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19045_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19040_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19035_lanthipeptide

Lanthipeptides: KTC92_RS18425_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

GNG++ T THEC+ NS + W CC

1

GNGVITTFTHECYYNSVSPASWGGCCK

27

48.1% NZ_CP084014.1and 6 others:

NZ_CP084014.1 Lanthipeptides: LCQ72_RS00100_lanthipeptideNZ_CP084014.1 Lanthipeptides: LCQ72_RS00095_lanthipeptideNZ_CP094679.1 Lanthipeptides: K5I24_RS13105_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12415_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12410_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12405_lanthipeptide

Lanthipeptides: LCQ72_RS00105_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

GNG++ T++HEC++N+W FTCC

1

GNGVLKTISHECNMNTWQFL--FTCC

24

48.1% NZ_FOZB01000002.1: Lanthipeptides: BM306_RS07850_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

G+G+ T++HECH+N+W FTCC

1

GDGVFRTISHECHMNTWMFI--FTCCS

25

48.1% NZ_JAHBEV010000004.1and 3 others:

NZ_JAHBEX010000010.1 Lanthipeptides: KII86_RS06785_lanthipeptideNZ_JAHBFD010000039.1 Lanthipeptides: KIJ16_RS07340_lanthipeptideNZ_LN890331.1 Lanthipeptides: LEKG_RS02295_lanthipeptide

Lanthipeptides: KII98_RS01100_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCC

26

+G++NT++HEC++NSW FTCC

3

SGVINTVSHECNMNSWQFV--FTCC

25

48.1% NZ_LT732526.1and 1 other:

NZ_LT732526.1 Lanthipeptides: BQ9856_RS23075_lanthipeptide

Lanthipeptides: BQ9856_RS23080_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

GNG++ T++HEC +N+W FTCC

1

GNGVIKTISHECAMNTWQFI--FTCCS

25

48.1% NZ_MSRJ01000005.1: Lanthipeptides: BKH06_RS03755_lanthipeptide

3

GIVNTLTHECHVNSWAVTEWFTCCD

27

G+V T++HEC++NSW FTCC

2

GVVTTISHECNMNSWQFI--FTCCS

24

48.1% NZ_NWMU01000024.1and 3 others:

NZ_NWMU01000024.1 Lanthipeptides: CO197_RS09145_lanthipeptideNZ_VMMF01000004.1 Lanthipeptides: HT717_RS01575_lanthipeptideNZ_VMMF01000004.1 Lanthipeptides: HT717_RS01570_lanthipeptide

Lanthipeptides: CO197_RS09150_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCCD

27

NG+ T++HECH+NS+ +FTCC

3

NGVFKTISHECHMNSFQF--FFTCCS

26

48.1% NZ_VDNV01000006.1: Lanthipeptides: FSV44_RS08765_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

G G++ T++HEC +NSW FTCC

1

GGGVIQTISHECRMNSWQFL--FTCCS

25

44.4% NZ_CP037940.1: Lanthipeptides: EQG49_RS07315_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

G+G++ TLTHEC +N++ TCC

4

GSGVIKTLTHECKMNTYQA--ILTCC

27

44.4% NZ_CP044492.1and 1 other:

NZ_CP066294.2 Lanthipeptides: IGS65_RS08185_lanthipeptide

Lanthipeptides: FSA31_RS00605_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCC

26

G+V T+++EC +NSW FTCC

5

QGVVPTVSYECRMNSWQHV--FTCC

27

44.4% NZ_CP046956.1: Lanthipeptides: ERJ70_RS03695_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCC

26

+G ++T++HECH+N+W FTCC

1

DGAISTVSHECHMNTWQFI--FTCC

23

44.4% NZ_CP071875.1: Lanthipeptides: J4I02_RS02880_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCC

26

G + TLTHEC A T W++CC

8

GGAICTLTHEC-----AGTHWYSCC

27

44.4% NZ_CP086142.1and 3 others:

NZ_CP086142.1 Lanthipeptides: LL065_RS25460_lanthipeptideNZ_CP086142.1 Lanthipeptides: LL065_RS25455_lanthipeptideNZ_CP086142.1 Lanthipeptides: LL065_RS25450_lanthipeptide

Lanthipeptides: LL065_RS25465_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

G G++ T THEC+ NS + W CC

1

GGGVITTFTHECYYNSVSPASWGGCCK

27

44.4% NZ_FNUH01000004.1and 1 other:

NZ_FOGM01000011.1 Lanthipeptides: BMX20_RS07220_lanthipeptide

Lanthipeptides: BLU50_RS05815_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCC

26

G+V T+++EC +NSW FTCC

5

QGVVPTVSYECRMNSWQSI--FTCC

27

44.4% NZ_LR134406.1: Lanthipeptides: EL272_RS00695_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

G G + + THEC+ N+ +T+ FTCC

1

GWGSIFSFTHECNTNT--MTQLFTCC

24

44.4% NZ_MSRU01000008.1: Lanthipeptides: BKH03_RS04355_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCCD

27

G+G+ ++THEC++NS V TCC

2

GDGVKWSITHECYMNSLQVL--LTCCS

26

44.4% NZ_QTVL01000002.1and 5 others:

NZ_QTVL01000002.1 Lanthipeptides: DWZ44_RS04150_lanthipeptideNZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14340_lanthipeptideNZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14335_lanthipeptideNZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02940_lanthipeptideNZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02935_lanthipeptide

Lanthipeptides: DWZ44_RS04155_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

G+G+ T++HEC++N+W FTCC

1

GDGVFRTISHECNMNTWQFI--FTCC

24

44.4% NZ_WBPF01000002.1: Lanthipeptides: F8162_RS00195_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCC

26

G +T++HECH N+W FTCC

2

KGQFDTISHECHWNTWQFL--FTCC

24

40.7% NC_012470.1and 42 others:

NZ_CAAHGW010000010.1 Lanthipeptides: E9435_RS08895_lanthipeptideNZ_CAAHHE010000002.1 Lanthipeptides: E9499_RS02930_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08675_lanthipeptideNZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05705_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08735_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08985_lanthipeptideNZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01075_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09255_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08770_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08920_lanthipeptideNZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02160_lanthipeptideNZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09650_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03445_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08815_lanthipeptideNZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03175_lanthipeptideNZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02475_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08475_lanthipeptideNZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09585_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09025_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08485_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08495_lanthipeptideNZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS10120_lanthipeptideNZ_CP018188.1 Lanthipeptides: BSR19_RS11185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05190_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02600_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06670_lanthipeptideNZ_CP035443.1 Lanthipeptides: ETT56_RS07260_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07305_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09825_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05340_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09695_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS10860_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05070_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06745_lanthipeptideNZ_NWMU01000024.1 Lanthipeptides: CO197_RS09155_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04325_lanthipeptideNZ_VMMF01000004.1 Lanthipeptides: HT717_RS01580_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05570_lanthipeptide

Lanthipeptides: SZO_RS10260_lanthipeptide

5

VNTLTHECHVNSWAVTEWFTCC

26

VNT++ EC NS + FTCC

5

VNTISAECRWNS--LQAIFTCC

24

40.7% NC_013928.1and 4 others:

NZ_CP023477.1 Lanthipeptides: CO204_RS01880_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS01085_lanthipeptideNZ_CP061071.1 Lanthipeptides: IBL27_RS01740_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07570_lanthipeptide

Lanthipeptides: SMUNN2025_RS01705_lanthipeptide

1

GNGIVNTLTHECHV-NSWAVTEWFTC

25

GNG++ T+T C + N+ V FTC

2

GNGVIRTITQGCRMPNNMQV--LFTC

25

40.7% NZ_AULU01000012.1: Lanthipeptides: H580_RS25790_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

G G V T T +C T WF CC

4

GCGWVCTYTLDC-----PGTRWFNCC

24

40.7% NZ_CP045267.1and 1 other:

NZ_CP045267.1 Lanthipeptides: FDZ14_RS00155_lanthipeptide

Lanthipeptides: FDZ14_RS00155_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

G+G+V T T EC++ ++A F CC

1

GDGVVKTATSECYLGTFA----FACC

22

40.7% NZ_CP049223.1and 4 others:

NZ_CP049225.1 Lanthipeptides: G6Z85_RS06555_lanthipeptideNZ_CP049228.1 Lanthipeptides: G6Z83_RS06555_lanthipeptideNZ_JAKWZB010000003.1 Lanthipeptides: MMO78_RS01405_lanthipeptideNZ_PNGO01000002.1 Lanthipeptides: CJ224_RS02730_lanthipeptide

Lanthipeptides: G6Z86_RS06445_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCC

26

G++ T++HEC +NS+ FTCC

5

QGVLPTVSHECRMNSFQHI--FTCC

27

40.7% NZ_CP051645.1and 2 others:

NZ_JAKVFF010000018.1 Lanthipeptides: MKR34_RS11425_lanthipeptideNZ_VDOJ01000018.1 Lanthipeptides: FSV48_RS11975_lanthipeptide

Lanthipeptides: HHJ99_RS13350_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCC

26

+G++ T++H+CH+NS+ FTCC

4

SGVIPTVSHDCHMNSFQFV--FTCC

26

40.7% NZ_CP117876.1: Lanthipeptides: PQ460_RS01735_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

G+G+V T T EC++ + A F CC

1

GDGVVKTATSECYLGTVA----FICC

22

40.7% NZ_JAFCGV010000005.1: Lanthipeptides: JQI09_RS04275_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

G+G+V T T EC++ ++A F CC

1

GDGVVKTATSECYLGTFA----FVCC

22

38.7% NZ_CP034248.1: Lanthipeptides: EIM92_RS14995_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCC

26

G++ T++HECH NS + W TCC

7

GGVICTISHECHYNSVSPAAWATCC

31

37.0% NZ_ALSD01000046.1and 5 others:

NZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06795_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS10995_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS1000000113590_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03150_lanthipeptideNZ_LT545678.1 Lanthipeptides: BJR96_RS11590_lanthipeptide

Lanthipeptides: SAG0161_RS1000000124770_lanthipeptide

5

VNTLTHECHVNSWAVTEWFTCC

26

VNT++ EC NS + F+CC

5

VNTISAECRWNS--LQAIFSCC

24

37.0% NZ_CAAHKQ010000003.1: Lanthipeptides: E9664_RS02165_lanthipeptide

2

NGIVNTLTHECHVNSWA

18

NG+ T++HECH+N+WA

3

NGVFKTISHECHLNTWA

19

37.0% NZ_CP046304.1: Lanthipeptides: FOC54_RS00030_lanthipeptide

2

NGIVNTLTHECHVNSWAVTEWFTCCD

27

+G++ T++H+CH+N++ FTCC

4

SGVIPTVSHDCHMNTFQF--MFTCCS

27

35.3% NZ_CAKMMP010000011.1and 5 others:

NZ_CP018620.1 Lanthipeptides: BS614_RS05680_lanthipeptideNZ_CP062165.1 Lanthipeptides: JNUCC31_RS16755_lanthipeptideNZ_FMVM01000006.1 Lanthipeptides: BLQ13_RS10365_lanthipeptideNZ_RIAS01000010.1 Lanthipeptides: EC604_RS18225_lanthipeptideNZ_VEJI01000010.1 Lanthipeptides: FS576_RS22075_lanthipeptide

Lanthipeptides: L6H98_RS19925_lanthipeptide

3

GIVNTLTHECHVNSWAVTEWFTCC

26

G+ T++HECH NS + + W TCC

11

GVFCTVSHECHYNSVSPSSWLTCC

34

33.3% NC_013928.1and 4 others:

NZ_CP023477.1 Lanthipeptides: CO204_RS01890_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS01095_lanthipeptideNZ_CP061071.1 Lanthipeptides: IBL27_RS01750_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07560_lanthipeptide

Lanthipeptides: SMUNN2025_RS09965_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

G NT++ +C NS + F+CC

1

GGRASNTISSDCRWNS--LQAIFSCC

24

29.6% NC_017912.1and 15 others:

NZ_BORO01000007.1 Lanthipeptides: KI343_RS07745_lanthipeptideNZ_CP007242.1 Lanthipeptides: KHU1_RS17410_lanthipeptideNZ_CP031424.1 Lanthipeptides: DXX91_RS18935_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS10440_lanthipeptideNZ_CP043809.1 Lanthipeptides: ETZ92_RS14260_lanthipeptideNZ_CP049904.1 Lanthipeptides: V753_RS18470_lanthipeptideNZ_CP053764.1 Lanthipeptides: HPQ66_RS18325_lanthipeptideNZ_CP061938.1 Lanthipeptides: IEN91_RS19800_lanthipeptideNZ_CP063768.1 Lanthipeptides: IM712_RS05205_lanthipeptideNZ_CP087137.1 Lanthipeptides: LOK79_RS18580_lanthipeptideNZ_CP092383.1 Lanthipeptides: MID02_RS19390_lanthipeptideNZ_JAEACM010000001.1 Lanthipeptides: I5F15_RS04355_lanthipeptideNZ_JAJNPN010000015.1 Lanthipeptides: LQ568_RS13285_lanthipeptideNZ_SDKF01000002.1 Lanthipeptides: EUA41_RS09950_lanthipeptideNZ_VDUT01000007.1 Lanthipeptides: FS412_RS14545_lanthipeptide

Lanthipeptides: MUS_RS20065_lanthipeptide

1

GNGIVNTLTHEC

12

G G V TLT EC

13

GGGGVCTLTSEC

24

27.6% NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21835_lanthipeptide

Lanthipeptides: CN325_RS21835_lanthipeptide

2

NGIVNTLTHECHVNSW

17

+G V TLT EC W

14

DGSVCTLTKECRPACW

29

26.5% NZ_WITJ01000001.1and 1 other:

NZ_WITJ01000001.1 Lanthipeptides: GHI93_RS00065_lanthipeptide

Lanthipeptides: GHI93_RS00065_lanthipeptide

2

NGIVNTLTHECHVN

15

NG V T THEC N

19

NGYVCTWTHECQAN

32

23.3% NZ_CP040409.1and 4 others:

NZ_CP040414.1 Lanthipeptides: FE331_RS04030_lanthipeptideNZ_CP040415.1 Lanthipeptides: FE330_RS03440_lanthipeptideNZ_CP040417.1 Lanthipeptides: FE328_RS00755_lanthipeptideNZ_CP040424.1 Lanthipeptides: FE321_RS03455_lanthipeptide

Lanthipeptides: FE336_RS03460_lanthipeptide

1

GNGIVNTLTHECH

13

G G+V TLT +C

2

GPGLVRTLTKDCP

14

23.3% NZ_CP051884.1and 2 others:

NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptideNZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide

Lanthipeptides: HGK68_RS15125_lanthipeptide

2

NGIVNTLTHEC

12

NG + T+THEC

15

NGWLCTITHEC

25

23.3% NZ_CYXV01000003.1: Lanthipeptides: ARB75_RS04585_lanthipeptide

2

NGIVNTLTHECHVNS

16

GI TLT EC++ +

8

GGIACTLTGECNIGT

22

21.2% NC_017621.1and 16 others:

NZ_CP039462.1 Lanthipeptides: E8M06_RS05390_lanthipeptideNZ_JABTZM010000032.1 Lanthipeptides: HRQ47_RS09675_lanthipeptideNZ_JAEVFQ010000010.1 Lanthipeptides: JNO64_RS06375_lanthipeptideNZ_JAFFHD010000003.1 Lanthipeptides: JN532_RS02075_lanthipeptideNZ_JAGFVG010000007.1 Lanthipeptides: J5581_RS04225_lanthipeptideNZ_JAIJZO010000001.1 Lanthipeptides: K5Q34_RS00965_lanthipeptideNZ_JAIMDS010000024.1 Lanthipeptides: K6V32_RS10650_lanthipeptideNZ_JAJUWV010000001.1 Lanthipeptides: LZF89_RS05505_lanthipeptideNZ_JAMDIS010000017.1 Lanthipeptides: M5P45_RS08180_lanthipeptideNZ_JAMYIU010000001.1 Lanthipeptides: NKE44_RS01780_lanthipeptideNZ_JAMYIX010000001.1 Lanthipeptides: NKE54_RS02675_lanthipeptideNZ_JAMYIY010000001.1 Lanthipeptides: NKE64_RS02785_lanthipeptideNZ_JAMYJP010000014.1 Lanthipeptides: NKE68_RS07350_lanthipeptideNZ_LR738722.1 Lanthipeptides: STREPSUIS_RS03955_lanthipeptideNZ_VZMP01000023.1 Lanthipeptides: F6P50_RS09295_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05700_lanthipeptide

Lanthipeptides: SSUD12_RS06540_lanthipeptide

1

GNGIVNTLTHEC

12

G+G V TLT +C

2

GSGFVKTLTKDC

13

21.2% NZ_AQQB01000068.1and 6 others:

NZ_BCEY01000024.1 Lanthipeptides: GOZ53_RS05100_lanthipeptideNZ_BCEZ01000067.1 Lanthipeptides: GOZ55_RS11230_lanthipeptideNZ_BCFC01000053.1 Lanthipeptides: GOZ35_RS07920_lanthipeptideNZ_BCFG01000017.1 Lanthipeptides: GOZ50_RS03220_lanthipeptideNZ_BCFI01000009.1 Lanthipeptides: GOZ54_RS02495_lanthipeptideNZ_CP019557.1 Lanthipeptides: BZG42_RS05725_lanthipeptide

Lanthipeptides: K738_RS01000000110290_lanthipeptide

1

GNGIVNTLTHEC

12

G+G+V TLT +C

2

GSGLVKTLTKDC

13

20.0% NZ_CP047935.1: Lanthipeptides: allorf_0499838_0500005_lanthipeptide

1

GNGIVNTLTHECHVNSWAVTEWFTCC

26

GN NT H ++ ++ +CC

10

GNRPANTEHHTAFHATYIYEQYPSCC

35

ctg36_38

Leader:

MSEHREGTLFYDTETGRYDIRFDLESFYGG

Core:

LHCGECFDVKVKNVWVPVRIEMGDDWYLVGLNVSRLDGLRVRM

Core with dehydrations:

LHCysGECysFDVKVKNVWVPVRIEMGDDWYLVGLNVDhaRLDGLRVRM

antiSMASH-DB 4.0 matches for ctg36_38

19.6% NZ_KB903814.1: Lanthipeptides: A3G1_RS0108055_lanthipeptide

5

ECFDVKVKNVWVPVRIEMGDDWYLVGLNVS

34

E FD+ PVR E+ D ++ VS

3

EAFDLDADGKSRPVREEINPDQDVLDAAVS

32

15.8% NC_021177.1: Lanthipeptides: SFUL_RS11355_lanthipeptide

4

GECFDVKVKNVWVPVRIEMGDD

25

GEC +V VPVR D

11

GECLEVARGYATVPVRDSKATD

32

13.2% NZ_CP035914.1: Lanthipeptides: allorf_1662461_1662682_lanthipeptide

21

EMGDDWYLVGLNVSRLDGLR

40

++ DDW+ + L R +G+R

25

QIPDDWHQIALKFRRANGIR

44

with 1 more sequence matches

11.3% NZ_CP047945.1: Lanthipeptides: allorf_0406889_0407083_lanthipeptide

21

EMGDDWYLVGLNVSRLDGLR

40

++ D+W+ V + R +G+R

25

QIPDEWHQVAVRFRRANGIR

44

allorf_28354_28485

Leader:

MQNREIYYS

Core:

IFLNNEWQINLIHIHAISHICCEGIFATNLSTSG

Core with dehydrations:

IFLNNEWQINLIHIHAIDhaHICysCysEGIFADhbNLDhaDhbDhaG

antiSMASH-DB 4.0 matches for allorf_28354_28485

14.7% NZ_BNBL01000026.1and 2 others:

NZ_CP021744.1 Lanthipeptides: SMD11_RS36805_lanthipeptideNZ_JACHJF010000014.1 Lanthipeptides: FHS36_RS34165_lanthipeptide

Lanthipeptides: IE295_RS34230_lanthipeptide

20

ICCEGIFATNLS

31

+CC+ IF T+ +

3

MCCDTIFTTDRT

14

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg36_27 - Class II

Cleavage pHMM score: 4.20

RODEO score: 0

Monoisotopic mass: 2945.3 Da

Molecular weight: 2947.2 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2965.2 Da N = 1; 2983.3 Da N = 2

ctg36_28 - Class II

Cleavage pHMM score: 4.20

RODEO score: 0

Monoisotopic mass: 2945.3 Da

Molecular weight: 2947.2 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2965.2 Da N = 1; 2983.3 Da N = 2

ctg36_38 - Class II

Cleavage pHMM score: -2.70

RODEO score: 0

Monoisotopic mass: 4997.6 Da

Molecular weight: 5000.8 Da

Number of bridges: 1

allorf_28354_28485 - Class II

Cleavage pHMM score: -4.90

RODEO score: 0

Monoisotopic mass: 3717.9 Da

Molecular weight: 3720.2 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 3738.2 Da N = 1; 3756.3 Da N = 2; 3774.3 Da N = 3

gnlProkkaBJAINHAM_41 - Region 1 - cyclic-lactone-autoinducer

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Location: 19,121 - 39,177 nt. (total: 20,057 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

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gnlProkkaBJAINHAM_52 - Region 1 - NRPS

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Location: 1 - 29,153 nt. (total: 29,153 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS domains

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NRPS/PKS modules

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

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Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 29153:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Cys - Cys) + (Me-Cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg52_4

Search NORINE for peptide: strict or relaxed

AMP-binding (533..926): Cys

nrpys: Cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Small clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Single AA prediction:: Polar, uncharged (aliphatic with -SH) (Cys)

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code(s):: Cys DLYNLSLIWK (94% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg52_7

Search NORINE for peptide: strict or relaxed

AMP-binding (547..937): Cys

nrpys: Cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Small clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Single AA prediction:: Polar, uncharged (aliphatic with -SH) (Cys)

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code(s):: Cys DLYNLSLIWK (88% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1614..2011): Cys

nrpys: Cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Small clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Single AA prediction:: Polar, uncharged (aliphatic with -SH) (Cys)

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code(s):: Cys DLYNLSLIWK (97% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaBJAINHAM_60 - Region 1 - ranthipeptide

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Location: 1 - 18,910 nt. (total: 18,910 nt) Show pHMM detection rules used

Region on contig edge.

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

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gnlProkkaBJAINHAM_69 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 16,388 nt. (total: 16,388 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

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gnlProkkaBJAINHAM_74 - Region 1 - RRE-containing

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Location: 2,440 - 17,387 nt. (total: 14,948 nt) Show pHMM detection rules used

Region on contig edge.

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

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gnlProkkaBJAINHAM_79 - Region 1 - ranthipeptide

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Location: 1 - 15,239 nt. (total: 15,239 nt) Show pHMM detection rules used

Region on contig edge.

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

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gnlProkkaBJAINHAM_101 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 7,503 nt. (total: 7,503 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

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gnlProkkaBJAINHAM_108 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 5,798 nt. (total: 5,798 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

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