LOCUS       gnlProkkaCBFFGENH_31   17570 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CBFFGENH_31.
ACCESSION   gnlProkkaCBFFGENH_31
VERSION     gnlProkkaCBFFGENH_31
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 20:15:46
            Original ID  :: gnl|Prokka|CBFFGENH_31
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17570
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17570
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6836:7570]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6837..7570
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..17570
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17570
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             464..820
                     /locus_tag="ctg31_1"
                     /transl_table=11
                     /translation="MVWSVKYRRKILSAEVEAYLQKLVQEIAEDKGFTVHLFECGEGDH
                     VHCFVSAPPKLSITAIVKYLKGISGRKLFERFPEIRNQLWKGELWNHSYYVEMVGSVSE
                     ENIRRYIEHQSKAY"
     CDS             complement(848..1195)
                     /locus_tag="ctg31_2"
                     /transl_table=11
                     /translation="MHDPHLHIGNGDTFLLKPRRSGSLDPPGSFQGIKRLPCLVQQLAD
                     FLGRLGRELFIPQILFMGFFLIIPVRMLLYPSFFVMLTLVITDIPELGCCIAHMPDEVR
                     IFPADLYGCFL"
     CDS             1250..2095
                     /locus_tag="ctg31_3"
                     /transl_table=11
                     /translation="MEETYQIHENFLYLENKIFRGMDQIKQLRIYPPEKGNCKIIVVYE
                     VSGQEELPQNGHELSIDLGLHNLMTCYDSGNGKTFILGRKYLALERYFHKEIARVQAQW
                     YGQQSGKGVKYLATSKHIRKLYKRKHDSVTDYLHKVTRYLAEYCREQGITCVVAGDIRN
                     IRREKDLGHRTNQKFHSLPYNRIYIMLEYKLKRYGIRFIKQEESYTSQCSPLSPKVGKR
                     YAEPSKRKERGLYRDGNRTYNADAVGAYNILRKYHSVSGVKKELSVTGLKTPEIIKVAV
                     "
     CDS             2543..3196
                     /locus_tag="ctg31_4"
                     /transl_table=11
                     /translation="MDYQSIVTFVMEMAGSVAFAASGAMVGVERNMDIFGVSVLGVATA
                     VGGGMIRDIVLGIIPPAVFTNPVYALVSVLASCIVFFIFYFKRELLQGHRRETYDKIML
                     AMDSVGLGIFTVVGVNTGIRQGYMDNVFLLVFLGTITGVGGGLLRDMMASVPPYIFVKH
                     IYACASIIGAVVCVYMNRFVGNVQAMVVSSIVVVLIRYLAAHYRWNLPRLSPHE"
     CDS             complement(3105..3617)
                     /locus_tag="ctg31_5"
                     /transl_table=11
                     /translation="MRKKLNITEGIFPMPVLMVATYNEDGSINVMNAAWGTMQERDTVA
                     LNLTETHKTVQNIKARGAFTVSIADAAHVTEADYFGVESGNREPDKFARSRLTATKSET
                     VDAPIINNFPPRTKRQSDKLSLTALNITCLILYGILPIHVVTAWADSSGNVLPDIGSAP
                     LQLMILP"
     CDS             complement(4108..5406)
                     /locus_tag="ctg31_6"
                     /transl_table=11
                     /translation="MEYIILLIFSFFTEAVILWQYAASLFSPSHSGKKRLTLLSVLYVL
                     LFFLSLLGQTWLNIISFFVINTVFLYIMFNLKLLLALFHSAILTAIMGISELAVLGMIS
                     RFFPHFLLEASVGLVFYTVFSKITFFAVVYLLSWLFKGNKAAQEPYGHSEILLMFIPLS
                     SILMMFTLLSIGETTAYAPPVDFLVTICAVFLLLVNLLVFGINQYNTKRSQEYADLQLL
                     LQKESDSVEYYEMMLAQNENQSILIHDIKKHLQSIRLLNEKNDSDKINDYIQQLMESSD
                     LKETTKLCDHEMLNSILCRYQRHCNDKHIIFHTDIRSGTVQHIYPRDLTSLFCNLLENA
                     VESAENIPDSFIELTVQKKENSPFLIIILINSCQNTPVYNPEGLPISHKSDNGRHGFGI
                     KSIKKVVKQYHGNLQMYYDNDSGTFHTILTLKQ"
     CDS             complement(5413..6120)
                     /locus_tag="ctg31_7"
                     /transl_table=11
                     /translation="MRILICDDDTLIIEQLKKYIESYFESNHLKCPELVSFTSGEALLT
                     DKGEKDIVFLDIEMPGMNGIYVGNELKKANRNVIVFVVTSYSEYLDEAMRFHVFRYLSK
                     PLDKQRFFRNLKDALAYYNSITLKIPVETKQAVYSFPASQIIAIEAQGRKVIVHTARQD
                     FDSIHNMNYWLEKLPQNSFFQTHRSFIVNFEHIVDFDHSTVHLSNPQITAYLTRRKYSS
                     FRNAYLLYLESMR"
     CDS             complement(6212..6541)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 57.2; E-value: 4.5e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg31_8"
                     /transl_table=11
                     /translation="MGNRIKIRRKELRIKQAELAERLNISNSHMSSIENGRQKPSLDIF
                     IQICNLLNVTPDYLLLGSMHAYNIPQDIIDKLRLCNQSDIELAGDFIELLVKRNNKATH
                     NEPKL"
     CDS             6837..6986
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_9"
                     /sec_met_domain="TIGR04223 (E-value: 2.7e-14, bitscore:
                     44.5, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKEVTKSVAKGMKAALDVVLRTEANTASCLIMYQPKAPKELMNY
                     RRNK"
     CDS             6986..7570
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_10"
                     /sec_met_domain="AgrB (E-value: 3.1e-36, bitscore: 115.9,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKCTDTVVNWMIRCNAINEADKELYKYALYSFFLLVSPLILAGV
                     IGFGLGSVKHGVALIFPFVVLRKFSGGYHAKNLHTCILGSGFLLFLCIMLSMHVQCDLK
                     LAIATVIASVSLITFSPIDSENRRLDTNEKRTYKKTTVFFVILFGLLDIALFLLGKYIY
                     TICFSVGILLTAGLQVPCIVKKMCKSTKNRL"
     CDS             7785..8168
                     /locus_tag="ctg31_11"
                     /transl_table=11
                     /translation="MTHKKEVVFSLLFVIMVLCTGCSDKDNGDTSKNNRTSGESFVQEE
                     TIESTDNTDNADGSSAPTPELKTPRTKKELEDALGTVNESGKWTPPAGSHIDPKTGNIL
                     NKDGVVVGTTQEPYSKARPGSQG"
     CDS             8165..8314
                     /locus_tag="ctg31_12"
                     /transl_table=11
                     /translation="MMIWCKKIMGGKDYEVYEKKLICSVFGHKCNSFDKFICNAGACCG
                     KYRN"
     CDS             8782..8940
                     /locus_tag="ctg31_13"
                     /transl_table=11
                     /translation="MALAQATKSHEPTYTINDAMDVLLSRLDEAIDDMESDRVQIVEEA
                     WAEIDAI"
     CDS             8950..9096
                     /locus_tag="ctg31_14"
                     /transl_table=11
                     /translation="MEKRKYKVVIAQSGKLDVKEKRNISFSNLNTGSMQRIFPKRLKSG
                     SCT"
     CDS             complement(9279..10643)
                     /locus_tag="ctg31_15"
                     /transl_table=11
                     /translation="MAERTKFLSYCIYSLMISLVVYPVSGHWIWGGGFISQMGFHDFAG
                     SCAVHMVGGVAALIGAIILGPRIGKYTKDGKSKAIPGHNLTVGALGVFILWFCWFGFNG
                     ASTVSMEGDAIVSAGKIFVTTNLSAAVATVTVMIITWVRYKKPDVSMSLNGSLAGLVAI
                     TAGCDTVSPTSAAIIGIASGFIVVFGIEFIDKVLKIDDPVGAVGVHGLNGAFGTLAVGL
                     FSDGSGTDWKGLLTGGGFHGFGVQFTGMIITIAWVVVTMTIIFQVIKHTIGLRVSAEEE
                     IAGLDSKEHGLASAYDGFAMAGVPTPMGTSIKAPVVTARPSAPAESVPELPKEGVHKLT
                     KVVIITRQNKLDEFMQAMNEIGVTGITITNVLGCGVQKGAPSYYRGVEMEMNLLPKVKI
                     EIVVSLVPVQKVIETAKAVLHTGQIGDGKVFVYDIENVVKIRTGEEGYLALQDTK"
     CDS             complement(10704..10991)
                     /locus_tag="ctg31_16"
                     /transl_table=11
                     /translation="MEFSAVNTIWVLVGAALVFFMQAGFAMVETGFTRAKNAGNIIMKN
                     LMDFCIGTPVFWLVGFGLMFGAGNGFIGKIGGIATEAHYGSGMLPDGVPF"
     CDS             complement(11290..13389)
                     /locus_tag="ctg31_17"
                     /transl_table=11
                     /translation="MAQNIPELYGSLVFNDKVMRSKLPKDMYKALKKTIESGTHLELDV
                     ANSVAVAMKEWATENGATHYTHWFQPMTNVTAEKHDSFISPTGDGQVIMDFSGKELVKG
                     EPDASSFPSGGLRATFEARGYTAWDPTSPAFIKDGTLYIPTAFCSYSGEALDKKTPLLR
                     SMQTLDKEATNLLHIIGNKDIKHVNTTVGPEQEYFLVDKELYKQRKDLVFCGRTLIGAP
                     APKGQEMEDHYFGALKPRVAAYMHDLDVELWKLGIPAKTKHNEVAPAQHELAPVFDTTN
                     VAVDHNQLTMEVMKKVADKHGLVCLLHEKPFEGINGSGKHNNWSMITDTGVNILDPGKT
                     PAENTQFLIFLTAVIKAVDEYADVLRISVASAGNDHRLGANEAPPAVVSVFLGDELTEV
                     LKSIENDEYFAGSRAVQMDIGAKVLPHFVKDNTDRNRTSPFAFTGNKFEFRMLGSEASV
                     ANPNIILNTAVAECVHQFAEQLKDVPEDKMEDAIHELIKKTIIDHKCVIFNGNGYTDEW
                     IEEAEKRGLFNLKSTPDALPQWIADKNIELFTKYHIFTKEEIESRYEIWLESYSKILNI
                     ESNTMVEMVQKDFLPSVFAYIDKVAATAVAKKSVVSDVSTASEGKLIKELSQLADEIST
                     GLETLKADTAKALATEDPLANAKAYQTVVLSDMDELRKSVDAAETLIPDALLPYPTYDK
                     LLFSV"
     CDS             13806..15227
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_18"
                     /sec_met_domain="GATase_7 (E-value: 3.4e-23, bitscore:
                     73.4, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGIKEECGVFGIYDLDGGNVVPSIYYGLTSLQHRGQESCGLAVS
                     DTKGERGNVKFHKDLGLVSEVLRQDVVRKYEGDIGIGHVRYSTTGASVAENAQPLVLSY
                     VKGTLALAHNGNLVNTPELKWELIQNGAIFHTTTDSEVIAFHIARERVHSKTVEEAVLK
                     TAKKIKGAYGLVVMSPRKLIAVRDPYGLKPLCLGKRGNAYVIASESCALTSVSAEFIRD
                     IEPGEILTITKDGLKSNKELASAAAKRAHCVFEYIYFARLDSTIDGVKVYDARIRGGKS
                     LAKSYPVEADLVTGVPESGLPAAKGYSEASGIPFAFAFYKNSYIGRTFIKPTQEERESS
                     VHLKLSVLESVVKDKRIVLVDDSIVRGTTIANLIHMLKEAGAKEVHVRISSPPFLHPCY
                     FGTDVPSNDQLIAASHSTEEICKMIGADSLGYMQTDYLEGMAGGLPLCKACFDGNYPME
                     IPDYTNAEFADIVKC"
     CDS             15497..15724
                     /locus_tag="ctg31_19"
                     /transl_table=11
                     /translation="MSQSKIKLNATEEVQEFVNAASRCDFDIDVYYNRFLIDAKSILGV
                     LSLDLTRELTVDCHGESREFDRTLKKFAVA"
ORIGIN
        1 gaactgagat ctacaggcgg aaccaccgta tataaacgga acaatcggac aacctataca
       61 aggattacag gcgtgaagcc cggaacctat actctgaaag tccgcccatg ggtcaaaatt
      121 aacggaagga aagcttacgg agactgggta tcctggggaa gaagaatcag ggtaaaataa
      181 aaagaaacag acaactgccc cttgtttagg ataataagcg ggaatcctcg gcaattcaat
      241 taccgagatg aaagcgcaaa ctgtgcatat ctgcactcat aataaataaa aataacaaaa
      301 cggttttcat tcaatttctc cctataaaaa gctgtatcca gcatcataaa aaagaaaata
      361 tgttcgatat tttattgcga aatttttgat atcatggtat catatatgta tgaaagaaaa
      421 tcttatacat tatcgcactt gtgtgtgcaa tattaattac catatggtat ggtcggtaaa
      481 ataccggcgg aagatattaa gtgcggaggt cgaggcatat ctgcagaaac tggtgcagga
      541 gatcgcagaa gataagggct ttacggtcca tctgtttgaa tgtggggaag gagaccatgt
      601 acactgtttt gtgtcagccc ctccgaaatt atccataact gcgatcgtga aatacctgaa
      661 ggggatttcc ggcaggaaac ttttcgaacg ttttccggaa ataagaaacc agctttggaa
      721 aggggagctg tggaaccatt cctattatgt ggaaatggtc ggatctgtat cggaagaaaa
      781 tatccgcagg tacatcgaac atcagagcaa agcgtactga tactatggag gagaggaaat
      841 gctgctgtca aagaaaacat ccataaaggt cagccgggaa tatgcgaacc tcatcgggca
      901 tatgtgctat gcagcatcca agctctggaa tgtctgtaat tacgagcgtc agcattacaa
      961 agaaactggg atagagcagc atccggactg gtattatcag aaaaaagccc ataaagagga
     1021 tctgtggtat aaacagctcc cgtcccagac ggcccaggaa gtctgcaagc tgctggacaa
     1081 ggcatggaag tctttttatg ccctgaaaag atccgggggg atcgagactc ccagaccgcc
     1141 gcggtttaag caggaaagta tccccattac ctatatgcag atggggatcg tgcatgagcg
     1201 ggatacggac agagtccgcc tgtcccttcc aaagacatta aaaaaatata tggaagaaac
     1261 atatcagatc catgaaaact ttctttacct tgaaaataag attttcaggg gcatggatca
     1321 gatcaaacag ctgcggatct atccgccgga gaagggaaac tgtaaaatta ttgttgttta
     1381 tgaggtttct ggccaggaag aacttccaca gaacggacat gaactgtcca ttgatctggg
     1441 actccataat cttatgacgt gttatgattc cgggaacggt aagacgttta tcttgggcag
     1501 gaagtacctt gcactggaaa gatatttcca taaagagatc gcaagggtgc aggcccagtg
     1561 gtatgggcag cagtccggaa agggagtaaa gtatctggct acatcaaaac atatcaggaa
     1621 gttatataag agaaaacatg attcagtaac ggattatctg cacaaggtca caaggtatct
     1681 tgcagaatac tgccgggaac aggggatcac ctgtgtcgtt gcaggggata tccggaatat
     1741 ccggagagaa aaagacctgg gacacaggac aaaccagaag ttccacagcc tgccgtataa
     1801 caggatctac atcatgctgg aatataagct gaaaagatat gggatccgtt ttataaaaca
     1861 ggaagaaagt tataccagcc agtgcagtcc gctgtcaccg aaagtgggga aaagatatgc
     1921 agagccgtcc aaacggaaag agagagggtt gtacagagat ggaaacagaa cctataacgc
     1981 agatgccgta ggcgcatata atatcctgag aaaatatcac tccgtatccg gagtaaaaaa
     2041 agaactgtcc gtaaccggac tgaaaacacc ggaaataata aaagtagctg tatagctcta
     2101 aagagcaaac agtagtggtg tcatggatgc accctgaaaa aaaggcggta tcccgcctta
     2161 attcagatgc tctggtaact cagttgccga gtaattcact tactatacta tgctgaaggt
     2221 gttcgcgaag tatataagtt tatctatatg aaatggaata aatagtcgat tttctgatac
     2281 tgattgagag taaagactct ttcacgtgac gttcaaaaaa tcgacttttt atcttggata
     2341 attcagtgga atctcctgct tcaattatga aaacattaag tgatgaacgg agatttactg
     2401 atatttttat agcaattcca gaaaataatg caattaagac agttcagcat tttcctgtct
     2461 ttcgtgcttt gcaggagtgc attagttgca ttgttttctg ggattataaa agaaagatag
     2521 gatggggagt taaaaaacaa atatggatta tcagtcaatt gtaacatttg ttatggaaat
     2581 ggccggttca gtggcgtttg ctgcttccgg agcgatggtg ggcgttgaac ggaatatgga
     2641 tattttcggc gtgagcgttc tgggagttgc aacagcagta ggcggaggaa tgatcaggga
     2701 tattgttctg gggatcatcc ctccggctgt atttaccaat cctgtatatg cactggtgtc
     2761 agtgcttgct tcctgcattg ttttctttat tttttatttc aagagagaat tgcttcaggg
     2821 gcacaggcgt gagacctacg ataaaatcat gctggcaatg gactctgtcg ggcttgggat
     2881 ttttacagta gtaggagtaa atacaggaat ccgccaggga tatatggaca atgtgttcct
     2941 gcttgtattt cttggaacca ttacgggagt aggcggcggt ctgcttagag atatgatggc
     3001 gagtgtaccg ccgtatattt ttgtaaaaca tatctatgcc tgtgcctcca tcattggtgc
     3061 agttgtatgc gtatatatga atcgatttgt gggaaatgta caggctatgg tagtatcatc
     3121 aattgtagtg gtgctgatcc gatatctggc agcacattac cgctggaatc tgcccaggct
     3181 gtcaccacat gaataggaag gataccgtat aaaatcagac aggtaatatt tagcgcagtc
     3241 aggctgagtt tgtctgactg tctttttgtt cgaggaggaa aattattgat aatcggagca
     3301 tctacagttt cagattttgt ggcggtcaga cggctgcggg caaatttatc aggctcgcga
     3361 ttaccggatt ctacaccgaa atagtcagct tctgttacat gtgcggcatc cgcgatgctg
     3421 acggtaaatg caccgcgtgc tttgatattc tgtacggttt tatgggtctc ggtaaggttc
     3481 aatgcaactg tgtcacgttc ctgcatcgta ccccaggcag cgttcattac attgatgctt
     3541 ccgtcttcat tataggttgc aaccatcaat acaggcatag gaaaaatgcc ttctgtaata
     3601 tttaattttt ttctcattac aacagcccct ttcagattca attgacagga taatatatcc
     3661 tgctataaat gagcaagttt gaaaaaatgc acaaaattat cctgctaatt tcataaatgc
     3721 ttcaaaatca tcacttgctt ttgcacatag gaatagatac tgatactttt cctgatgaac
     3781 ggcactacag attcgatgat atccatcttg aaaagatcga tatttgccag ttcctgtgac
     3841 acaaatacaa tgtgccagtg acatcagcag ccagtatctc tgtatttcct ttgagaaacg
     3901 gatctggtat gtatccagtg ccagacggtt tttacattgc ctgaaaaata tctcgatcgg
     3961 ccatcgacac acataacagg aaaagatctc tttcttttat gcaaaatcac gaacttgctc
     4021 atttatagtg atataaaaca acatcaatgc atgctgaaat atgtaaaaag gcaatcgtat
     4081 aaaattgcga ttgccagatt ttaatattta ctgctttaag gttaggattg tatggaaggt
     4141 accggaatca ttatcataat acatttgcaa atttccatgg tactgtttta cgactttttt
     4201 aatgcttttg attccgaatc catgtctgcc attgtctgat ttatgggata taggaagtcc
     4261 ctctggatta tatacagggg tattttggca ggagttgatg agtatgataa taagaaaggg
     4321 tgaattttct ttcttttgta cggtgagctc aataaaagag tctggaatat tctctgctga
     4381 ttccactgca ttctccaata agttacagaa taaagaagtc aaatcgcgcg gatatatatg
     4441 ttgtaccgtg ccgcttctga tgtcagtgtg aaaaataatg tgcttatcat tgcagtggcg
     4501 ctgatagcgg cacagaatgg agtttagcat ttcatgatca cagagttttg tggtttcctt
     4561 taagtcggaa gattccatga gttgttgtat atagtcattt attttatcgg aatcattttt
     4621 ttcgttcagt aatctgattg attgaagatg tttctttata tcgtggatca aaatgctctg
     4681 gttctcgttt tgtgcaagca tcatttcata gtattcaaca gaatcggatt ctttctggag
     4741 cagtaactgc aaatcggcat attcctgtga tctttttgtg ttatattggt tgattccaaa
     4801 tacaagtagg ttgaccagca acagaaaaac ggcacagatt gttactagaa aatcaaccgg
     4861 tggggcatat gcggttgttt caccaataga aagaagagta aacatcataa gaatagagga
     4921 aagcgggatg aacatcaaga gaatttcgga gtgaccgtac ggttcttgag ctgctttgtt
     4981 ccccttgaag agccaactta acaagtaaac gactgcaaaa aaggtaattt tgctaaatac
     5041 ggtataaaaa acaagtccga cacttgcttc taagagaaaa tggggaaaga atcttgatat
     5101 catccccaaa actgcaagtt cagatattcc cataatcgct gtaagtatag cggaatggaa
     5161 gagtgccaat aataacttga ggttaaacat tatatagagg aaaacagtgt ttatcacaaa
     5221 aaaactgata atattcagcc atgtttgccc aagcagggaa agaaaaaaca acagtacata
     5281 aagaacactt aatagagtca gtctcttttt accgctatga gaaggggaaa aaaggctggc
     5341 ggcgtactgc cataagataa ccgcttctgt aaaaaaacta aaaataagta aaataatata
     5401 ttccatttat tttcacctca tgctttccag atatagtaga tatgcatttc tgaaggaact
     5461 gtatttcctg cgtgtcaggt aagcggtaat ctgaggattt gataaatgta cggtggagtg
     5521 atcaaagtcc acaatatgtt cgaagttaac aataaagctc cggtgtgtct gaaaaaaact
     5581 gttttgggga agcttttcca accagtaatt catattatga atagagtcaa agtcctgacg
     5641 ggcagtatgt acaattactt ttcgcccctg agcttctatg gcaataatct gcgaagcagg
     5701 aaacgaatat accgcctgtt ttgtttccac aggaattttg agtgtaatgg aattgtaata
     5761 agctaaggca tccttcagat ttcggaaaaa acgctgctta tctagaggtt tggaaaggta
     5821 acggaataca tgaaaacgca ttgcttcatc caaatattca gaataagagg tgacaacaaa
     5881 aacgatcaca tttctatttg ctttttttaa ttcattccca acatagattc cattcatgcc
     5941 aggcatttcg atatccagaa aaacaatatc cttttcacct ttgtcagtta acaaagcttc
     6001 accactggta aaagaaacta attcaggaca ttttaaatgg ttggactcaa agtaggattc
     6061 gatatacttc ttcaattgtt caatgatcag agtgtcatca tcacaaatta aaatacgcat
     6121 tttttcacct gactttctaa atagatgtat gtgtacatct tatcacatag aatttccaaa
     6181 tgcaaaaaat gcgtatgaaa agacaattta attacaattt tggttcatta tgtgttgctt
     6241 tgttatttcg ttttacaagc agttcgataa agtctccggc aagctctatg tcggattgat
     6301 tacataaccg tagtttatca ataatatcct gtggaatatt ataagcgtgc atactgccga
     6361 gcagaaggta gtcaggtgta acattgagta aattacaaat ctgaatgaaa atatccagac
     6421 ttggtttttg ccttccgttt tcgattgatg acatatggct attggatata tttaatcttt
     6481 cggcaagttc tgcctgtttt atccgtaatt cttttctgcg tattttgatg cggtttccca
     6541 taccttcata ttgaaattct atttatccca ccttctttca gtagaatttt accaatagaa
     6601 ctaaataaaa agaagaatgt aacaaagaac tattctgcaa tatattaaac aaactgatat
     6661 ttatatataa ataattctgt atcacatatt atttttcgta gaaaagaggg aaattatcca
     6721 atattgtaaa gaatcattcc gttcattcca aaggggtcgt ttatttgatt aaagtggtat
     6781 atgattgctt atgtgaaaat caatgacaaa ttttagtgga aaggagagag gtcattatga
     6841 agaaagaggt aactaaatcg gttgcaaaag gaatgaaagc agcattagat gttgtgttac
     6901 ggacagaagc taacacagct tcttgtctta tcatgtatca gcctaaggca ccgaaagaat
     6961 taatgaacta caggagaaac aagtaatgga aaaatgtaca gatacagtag taaattggat
     7021 gatccggtgt aatgcgataa acgaggcgga taaggaactt tacaagtatg cattatatag
     7081 tttttttcta ttggtatcac cacttatcct tgcaggagtt attggctttg gcttgggaag
     7141 cgtaaaacac ggagttgctc ttatttttcc gtttgtggtt ctgagaaaat ttagtggtgg
     7201 ttatcatgca aaaaatttgc acacttgtat tcttggatct ggttttctat tgtttctgtg
     7261 cataatgtta tcaatgcatg tgcaatgtga tttgaagttg gcaatagcta cagttattgc
     7321 gtctgtgagc ctgattacat ttagtccaat agacagtgaa aacagaagac ttgatactaa
     7381 cgagaaaagg acatataaaa aaacaacagt gttcttcgtg atactgtttg ggctgttaga
     7441 tatagcttta tttttgctgg gaaagtacat ctatacaatc tgtttttctg ttgggatatt
     7501 actgacagca ggcttacaag taccttgtat cgtaaagaaa atgtgtaaat cgaccaaaaa
     7561 cagactgtaa atgtcgtttg gtgcaaaagg ggttgaaatc atggcaaaaa taaagataat
     7621 aaagtttgtc attgatttga tcaaagttct ttatttacag ttaattcagt ttgttcattg
     7681 aaagggagtg gattccaatg ggacaatgat agaattctat cactttaaat tgagtagttc
     7741 ggttcggagt agttaaacgg gcataatgga ggtaaaagat taaaatgaca cataagaaag
     7801 aagttgtttt tagcttgttg tttgtaataa tggtgttatg tacaggctgc agtgataaag
     7861 ataatggaga tacgtctaaa aataacagga cttcaggaga atcatttgtt caagaagaaa
     7921 ctattgagag tacagacaat acagacaatg cagacggcag ctcggcacca acgccagaac
     7981 tgaaaacgcc ccgaacgaaa aaggaattgg aagatgcgct tggtacagtg aatgagtcgg
     8041 gaaaatggac gccaccagcc ggttctcata tagatcccaa aacaggtaat atactgaata
     8101 aagatggggt cgtggttgga actacgcagg aaccttatag taaagcacgt ccaggttctc
     8161 aaggatgatg atatggtgta aaaaaattat gggaggaaaa gattatgaag tatatgagaa
     8221 aaaactcatt tgtagtgtgt ttggtcataa gtgcaattct tttgacaagt tcatttgcaa
     8281 tgccggtgct tgctgcggaa aatacaggaa ttgaaacaag ctctgtcacg agaagcgtac
     8341 cgggatatta caagtgcaca gggtcggatg taaatatcag atcaggccct ggaacacaat
     8401 atacaatagt aggcacattg aattatggca caaaagtata tgtatattct atcagtaatg
     8461 ggtgggccaa aatttctctt ggcggcattt accgttatgt tagtgccgat taccttcggg
     8521 agctttaagg aaaaacattt aatataaacg aggcataggt aaatagctgt atgggctgcc
     8581 gcactgaaaa gtttggtgcg gcagcacttt tgtttacttt tttaattgaa actacaaatg
     8641 gacaaattct aaaaaacgtc ccaaaaacag tattctgtgt ttgggttata aagacaaatt
     8701 taaaatatat agatatttcc ggtggttcgt ggtatgataa aaatagaaac aaaagtgcta
     8761 tttcaagaaa gggtgatggt tatggcattg gcacaggcaa caaaatccca tgaaccaact
     8821 tatacaatca atgatgcaat ggatgttctt ttgtcaaggc tggatgaagc cattgatgat
     8881 atggaaagtg acagagtgca gatagtggaa gaagcatggg cagaaattga tgcaatataa
     8941 ggggtacgga tggaaaaaag aaaatacaaa gttgtaattg cccagagcgg caagctggat
     9001 gtgaaggaaa aaagaaatat atccttcagc aatttaaata ccgggagtat gcagaggatt
     9061 tttcccaaaa gattaaaaag cggttcttgc acttgacaca cttcctacca gatataatac
     9121 aataggcttc cgatatcgtg gctatgatat ttacatgaaa tatactgcct gttttttaac
     9181 gccattggaa ttgttagaaa gaaagattaa aataagagac accagcaatc aatacgctga
     9241 tgtctcttat taatattacc tgattgttga taaatgattt actttgtatc ctgcagtgcg
     9301 agataacctt cttcgcctgt acggatctta acgacatttt caatgtcata tacaaatact
     9361 ttaccatcac caatctgacc ggtatggagg actgccttgg cagtttcgat aactttctgt
     9421 acaggtacga gacttacaac aatctcaatt ttgaccttag gaagaagatt catttccatc
     9481 tcaacaccac gatagtagga tggagcacct ttctgtacac cgcatccgag aacgttcgta
     9541 atagtgatac ctgtaacacc gatctcattc attgcctgca taaattcatc aagcttattc
     9601 tgacgggtga tgataacaac ttttgtaagc ttatgaacgc cttctttcgg aagttcagga
     9661 actgattcag caggagcaga aggtctggct gtgacaacag gagcttttat ggaagttccc
     9721 ataggagtcg gaacaccagc cattgcgaaa ccgtcataag cacttgcaag accatgttct
     9781 ttggagtcaa gacctgcgat ctcttcttca gctgaaacac gaagtccgat tgtatgtttg
     9841 attacctgga agataattgt catagtaaca acaacccatg cgattgtgat gatcatacca
     9901 gtgaactgaa caccaaatcc gtggaagccg ccgcctgtaa ggagtccttt ccagtctgtg
     9961 cctgatccgt ctgagaaaag accaactgca agggtaccga aagcaccgtt taaaccatga
    10021 acaccgacag caccaacagg gtcatcaatt ttcagaacct tgtcaataaa ttcaatacca
    10081 aatactacga taaaaccgga agcaataccg atgattgctg cggatgtagg agaaactgtg
    10141 tcgcatcctg ctgtaattgc tacaagtcct gcaagagaac cgttcagaga catggaaaca
    10201 tccggttttt tgtaacgtac ccatgtgatg atcataacag ttacagttgc aacagctgct
    10261 gaaaggttag tagtaacgaa gattttaccg gcacttacga ttgcatcgcc ttccatactt
    10321 actgtggaag caccgttaaa tccgaaccag cagaaccaga ggataaatac acctaaagcg
    10381 ccaactgtaa ggttgtgtcc cgggatagcc tttgatttgc cgtcctttgt atatttaccg
    10441 atacgaggtc caaggatgat ggcaccgatc agagctgcca caccacctac catatgtact
    10501 gcacaggaac ctgcgaaatc gtggaatccc atctggctga taaatccacc gccccagatc
    10561 cagtgtccgg ataccggata tacaacaaga ctgatcataa ggctgtagat gcaataggaa
    10621 aggaacttgg tacgttctgc cattgcaccg gaaacaattg ttgcggatgt tgcacagaat
    10681 actgtctgga agattaagaa tgcctagaaa ggaactccgt caggaagcat tcctgaacca
    10741 tagtgtgctt ctgtggcaat accaccgatc tttccgataa atccattacc tgcaccaaac
    10801 atcagaccga agccgaccag ccagaagacc ggggttccga tacagaagtc catcaggttt
    10861 ttcataataa tgttacctgc gtttttggct cgtgtgaagc ctgtttctac cattgcgaat
    10921 ccggcctgca taaagaagac cagcgcggcg ccgaccagca cccatattgt gtttactgcg
    10981 gaaaattcca taataatatt cctccctcat aaaaatttcc tcatatttta taaaatgcaa
    11041 aaagcgcgat gcctggaaat gtagccagtt catcgcgctt ttgcgaatat aaaatccata
    11101 tttatagtgt attgcataac tgatgtaata gaaaagacat ttcgtatgac tgtatgcaat
    11161 gcagtttaaa atcaaaatta tatgtaaaac aggagaacat caaaatatcg tgtgattaat
    11221 ggatgaggaa atcgataatg aattatgaag tagagttcat aaagatattc ccctgttatt
    11281 acctgttaat taaacggaaa acagaagctt gtcatatgta ggatatggaa gcagtgcatc
    11341 cggaatcaga gtttctgctg catctacaga ctttctgagt tcatccatat cagaaagaac
    11401 aactgtctgg tatgcttttg cattagccag aggatcttct gtagcaagcg ctttggcagt
    11461 gtctgctttt aaggtctcaa gacctgtgga aatctcatca gcaagctgtg acagctcttt
    11521 gatcagtttt ccttcagaag ctgtgctgac atctgaaaca actgattttt tagcaacagc
    11581 agtagctgca actttgtcga tatatgcgaa tacagatgga aggaaatcct tctgtaccat
    11641 ttcaaccata gtattggact caatgttaag aatcttggaa taggattcca gccagatctc
    11701 ataacgggat tcaatttctt cttttgtgaa gatatgatat ttggtaaaga gttcaatatt
    11761 tttatctgcg atccactgag gaagagcatc tggtgtagat ttcaggttaa agagacctcg
    11821 tttctcagct tcttcgatcc attcgtctgt ataaccgttt ccgttaaaga taacacattt
    11881 atgatcaata attgtcttct tgatcagttc gtggattgca tcctccatct tgtcttccgg
    11941 tacatccttt aactgttctg caaactggtg aacacactca gcaacagcag tgtttaaaat
    12001 aatgttcggg tttgcaacag aagcttcgga accaagcata cggaattcga atttgttacc
    12061 tgtaaatgcg aatggtgaag tacggtttct gtctgtattg tcttttacga aatgtggaag
    12121 tacttttgca ccgatatcca tctggactgc gcggcttcct gcaaaatatt cgtcattttc
    12181 gatagatttt aatacttctg tcagttcatc accgaggaat acggatacaa cagcaggcgg
    12241 agcctcgttt gcaccaagac ggtgatcatt tcctgcactt gctacagaaa tacgaagtac
    12301 atctgcgtat tcatcaactg ctttgataac agctgtcagg aaaatcagga actgtgtatt
    12361 ttcagcaggt gtttttcccg gatcaaggat atttacaccg gtatctgtaa tcatagacca
    12421 gttgttgtgt ttaccacttc cgttgattcc ctcaaatggt ttctcgtgaa gaaggcatac
    12481 aagtccgtgc ttgtcggcaa ctttcttcat tacttccatt gttaactggt tgtggtcaac
    12541 cgcaacgttt gttgtatcga atacaggagc cagctcatgc tgtgcaggag caacttcgtt
    12601 atgttttgtt ttggcaggaa taccaagttt ccagagctct acatccaggt catgcatata
    12661 agctgcgaca cgaggtttca gagcaccgaa gtaatgatct tccatttcct ggcccttagg
    12721 agcaggagca ccgatcagtg tacgtccgca gaatacaagg tcttttctct gtttgtataa
    12781 ttccttgtct accaggaagt attcctgttc aggacctaca gttgtattta cgtgtttgat
    12841 atctttattt cctattatat ggagaaggtt tgtagcttct ttatcaagtg tctgcatgga
    12901 acgaaggaga ggagtctttt tatcaagagc ttctccgctg taggagcaga atgctgtagg
    12961 aatgtaaagg gttccgtctt tgatgaatgc cggtgatgtc ggatcccatg ctgtatatcc
    13021 tcttgcctcg aatgtggcac gaagaccgcc tgacgggaaa ctggaagcat ccggctcacc
    13081 ttttacaagt tctttacctg agaaatccat gatcacctga ccatctcctg taggagaaat
    13141 gaagctgtca tgtttctctg cagttacgtt tgtcattggc tggaaccagt gagtataatg
    13201 agtggcgccg ttctcggtag cccattcttt cattgcaaca gcaacggagt tggcaacatc
    13261 aagttcaagg tgtgtaccgc tctcgattgt tttctttaat gctttgtaca tgtcttttgg
    13321 cagtttactt ctcattactt tgtcgttgaa gaccaggctg ccgtacagtt cagggatatt
    13381 ctgtgccata taggtactct cctttcggtt tgcaatattt tctgaatatg tgtagtgccg
    13441 ctgcagatca ccattgtgac tgcctgcggt tttcgtctca tagaaaattc ctcatcgaac
    13501 attttctatg aaacgaaagt tttataaaac gaaaaaagcg ccctggatga gatctctgta
    13561 gatctttcca aagcgccttt gctttatgtg ctgtactata aacgaaatga aaacagatgt
    13621 caagcacttt ttttgaaaaa attcagaaaa aatttttgag atatggcaaa aaaaggatag
    13681 gttgacaaat ttgtttctat tattataatt tgattttgga acccgtcaaa cataagaaaa
    13741 caatgtcagc gggttttgaa agtaaagtta aagtcagaca agagaatacg atcggaggaa
    13801 atcagatggc tggaataaaa gaagagtgcg gcgtctttgg aatttatgat ctggatggcg
    13861 gcaatgtagt tccgtccata tattatggac tgacttccct gcagcacaga ggacaggaat
    13921 cctgcggact tgcagtttct gatactaagg gagagcgtgg aaatgtgaag tttcataagg
    13981 atctgggact tgtaagtgag gttctcagac aggatgttgt ccgtaaatat gagggagata
    14041 ttggtattgg tcatgtaaga tattccacaa caggagcttc tgttgcagag aatgcacagc
    14101 cccttgtttt gtcttatgta aagggaactc ttgcacttgc acataacgga aatctggtta
    14161 atacaccgga actgaaatgg gaactgatcc agaatggagc gattttccat acaactacag
    14221 attcagaggt tattgcgttc catatcgcaa gagaacgtgt gcattctaaa acagtagaag
    14281 aggcagtgct aaagactgca aagaagatca aaggtgcata tggtctggta gttatgagcc
    14341 cgagaaaact gatcgcagtc cgcgacccat atggactgaa accattgtgt ctcggtaaaa
    14401 gaggaaatgc ttatgttatt gcttctgaga gctgtgctct gacatctgta agtgcggaat
    14461 ttatccgtga cattgagccg ggtgagattc ttacgatcac aaaagacgga ctgaagtcaa
    14521 ataaagagct tgcgtctgct gctgcaaaac gcgcgcattg tgtgtttgag tatatatatt
    14581 ttgcaagact tgacagtacc attgatgggg tgaaggtcta tgatgccaga atccgcggtg
    14641 gtaaatctct tgccaagtct tatcctgtag aggcagatct tgtaacaggt gtaccggagt
    14701 ccggactccc tgctgcaaag ggatactccg aagcatcagg aatcccgttt gcatttgcgt
    14761 tctataaaaa cagctatatt ggaagaacat ttatcaaacc gactcaggaa gaacgtgagt
    14821 ccagcgttca tctgaaactg agtgtgctgg aatctgttgt aaaagataag aggattgttc
    14881 tggtggatga ttctattgtt cgtggaacaa ccattgcaaa cctgatccac atgttaaaag
    14941 aggcgggagc aaaggaagtg cacgtacgta tcagttcacc gccattttta catccatgtt
    15001 atttcggaac ggatgtgccg tcaaatgatc agctcattgc agccagccac agcacggagg
    15061 aaatctgtaa aatgatcgga gcagattctc ttggctacat gcagacagat tatctggaag
    15121 gaatggcggg cggcctgccc ttatgtaagg catgcttcga tggaaattat ccgatggaga
    15181 ttccggatta tacaaatgcg gagtttgcag atattgtgaa gtgttaagtc gcaaaaattc
    15241 ataaaaaatg cagaaacctg tcgatgatat atggaatcaa tctcacataa tggtaaaacc
    15301 aatataggat gaagtcatac ataatgtata aaataatgct gtgaaaacat atataaacga
    15361 acaaaatgca caatagaacc cctgcgcttt atgaaaattg gataaattta aaaacttgac
    15421 aaattctgaa atgtggaaca taatatgggc gtctgataga aaaaaacaaa gaatgttttc
    15481 agaaagggtg atcacgatgt cacagagtaa aatcaagtta aatgcaaccg aagaggtgca
    15541 ggaatttgtg aatgctgcaa gcagatgtga ttttgatatt gatgtttatt acaacagatt
    15601 tttaattgat gccaaatcaa tccttggtgt acttagtctg gatctgacca gagaactgac
    15661 agtagactgc cacggggaga gccgggaatt tgatcgtaca ttgaagaaat ttgcagttgc
    15721 ataaatttta catttttata accgaataat tatcgcagag aagacgggtc tggaagatga
    15781 acttctacag attcgttttt tctgtattat gactgtgttc agagtaattc cataaaatat
    15841 aactgcttca tagtttatca gaaggaactt atttgatttg tttttgctta aaaacgggaa
    15901 attcattatt gacaaacgaa aaaaaatgtt ttatagtata gcatattttt aaagaaagcc
    15961 aattgaacat attattatag aagatatgat gatctgacaa aggcgtcaga tgcagaatac
    16021 cagatgggtc aagtgccctc tgatagctgc atctgacgct tttttattaa caaaggatga
    16081 tggaggagga aatcaaaatg gcagtgaaat acgtatttgt tacaggagga gttgtttccg
    16141 gtcttggaaa gggaatcaca gctgcatctc tggggcgtct tctgaaagcg agaggatatc
    16201 aggtaaccat gcagaagttt gatccttata tcaatatcga ccccggaacc atgaacccga
    16261 ttcagcacgg agaagttttt gtaacagacg atggtacaga gacagacctg gatctgggac
    16321 attatgagag attcattgat gagagtcttg ataaaaattc caatgtgaca accggtaagg
    16381 tttactggtc tgttcttcag aaagaacgtc acggggattt cggcgggggt accgtacagg
    16441 taattcctca tattacaaat gagattaaga gtcgtttcta ccgcgccaaa tcaccggagg
    16501 aaaacaagat tgccattatc gaggtgggag gaacagttgg tgatattgaa agccaaccgt
    16561 tcctggaagc aattcgtcag ttccagctca atgtgggaca tgacaatgca atcctgattc
    16621 acgtaacatt aattccttat ttaaaggcat ctgaagaact gaaaacaaaa cctacacagg
    16681 caagcgtaaa ggaacttcag ggaatgggaa ttcagccgga tgtactggtg tgcagaagtg
    16741 aacatgagct gacagaggac attaaagaaa aaatcgcttt attctgcaac gtacctgtat
    16801 cacatgtact tcagaacctg gatgtggaat atttatatga agctcctctt gcaatggaaa
    16861 gagagaagct tgcagatgta gttctttcaa gtctccgtct ggaaaacaga aaaccggatt
    16921 taagtgactg ggaggaaatg gtagaaagtc tgagaaatcc gaataaaaca gtaaagatcg
    16981 caattgtagg aaaatataca cagcttcatg atgcatatct cagtgtagta gaggcactga
    17041 aacatggcgg aatttcctgc agagccaagg tagagcttga ctggatcgat tccgaagaac
    17101 tgacagagaa gaatctggat cagcagcttc acaatgtaga tggtatcctg gttccgggtg
    17161 gtttcgggaa cagaggtaca gaaggaatga tcctggcagc acagtatgca agagtacata
    17221 agattccata tcttggaatc tgtctgggaa tgcagatggc aattgtagaa ttcgcccgtc
    17281 atgtacttgg atacgaagat gcaaacagta ttgaactgaa tccggagaca aagcatccgg
    17341 taattgcatt aatgccggat caggaagata tcgaagatat cggtggaacc ttaagacttg
    17401 gaagttatcc atgtattctt gcagaaggtt ccagatccta tgaactcttt ggcaaaaaag
    17461 aaatccatga gcgccacaga catcgttatg aagtaaacaa tgcattccgt aaagaacttc
    17521 aggagaaagg aatgaatatc gtaggaactt cccctgataa tcatattgta
//
