LOCUS       c00003_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CBFFGENH_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 21:57:46
            Original ID  :: gnl|Prokka|CBFFGENH_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 50511
            Orig. end    :: 73760
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[60511:63760]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1552..3009
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_48"
                     /sec_met_domain="FGGY_C (E-value: 2e-37, bitscore: 122.3,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 1.7e-78, bitscore: 257.1,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEDSGKICNIVSKEYPLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRTKVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKEKLSEYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSEDVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENNVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARSLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(3084..4019)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg3_49"
                     /sec_met_domain="LysR_substrate (E-value: 1.7e-32,
                     bitscore: 106.0, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 6.8e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIEAVEKVMDIENNLENFLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFEHYTYQKEQ
                     LLLAVPKNYSVNTRLQEYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELIFYKLPG
                     QSSKRTVFFYWKKGRYISRAMKEFLKLPFS"
     CDS             4169..5593
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_50"
                     /sec_met_domain="Lyase_1 (E-value: 4.9e-94, bitscore:
                     308.7, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 1.6e-21, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHVIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             complement(5703..7388)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_51"
                     /sec_met_domain="FTHFS (E-value: 8.9e-275, bitscore: 905.6,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKRVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_52"
                     /sec_met_domain="OKR_DC_1_C (E-value: 4.6e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 1e-125,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEHLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_53"
                     /sec_met_domain="Spermine_synth (E-value: 5.7e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 8.5e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_54"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 7.1e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 8.3e-35,
                     bitscore: 113.4, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKIDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWDYDEKFKKAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_55"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 3.6e-14,
                     bitscore: 46.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTGASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13284..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_56"
                     /sec_met_domain="PAD_porph (E-value: 8.3e-128, bitscore:
                     419.6, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSQAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGDFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTRED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14489..15367
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_57"
                     /sec_met_domain="CN_hydrolase (E-value: 2e-55, bitscore:
                     181.4, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGIYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             15670..16131
                     /locus_tag="ctg3_58"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIVLLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             16335..21044
                     /locus_tag="ctg3_59"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYDTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDELPSCLQLLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPDTGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGTQSMEVLGVQQQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGIDDAGNQL
                     NPENYKETVEKPVSCQVTRQETGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGEAETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEMVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEAYVKAKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYANSGGYSGGYGSYQGGSM
                     AGSSKTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             21041..21928
                     /locus_tag="ctg3_60"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSKS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             22120..23211
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_61"
                     /sec_met_domain="Peripla_BP_3 (E-value: 1e-32, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
ORIGIN
        1 tcaagaaagc cggatgtaac gcactttgcg tatatcttgg aaacttcgga ccggaaattt
       61 ccgaaacact tcttgctaaa cacttcgaag gaccgaagat gttctgtgca gcagctgaag
      121 aaacacaggg cgacctgatc cagggacgtg gagatgcata ctgcggtatg ttaaatgcaa
      181 gctacaactt acagcttcgt aatgtaaaag catatattcc ggaatatccg gttggtgatg
      241 cagaagactg cgcagatatg atccatgact tccttccaat cgcaagagca gttgaaggat
      301 taagcaactt aaagatcatc agctttggac cacgtccaac aaacttcctt gcttgtaacg
      361 ctccgatcaa acagctttac aaccttggtg ttgaaatcga agagaactct gaacttgatc
      421 tgttcgaagc attcaacaaa catgcaggag atgagagaat cccggcagtt gttaaagaaa
      481 tggaagaaga acttggtgca ggaaacaaga aacctgaaat tcttgagaaa cttgctcagt
      541 atgaactgac tctgaaagac tgggtagagg ctcacagagg atatcgtaaa tatgtaacat
      601 taacaggaaa atgctggccg gcattccaga cacagtttgg atttgttcct tgctatgtaa
      661 acagccgtct gactgctcag ggcattccgg tatcctgtga agttgatatt tatggtacat
      721 taagtgagtt catcggaact gttgtaagcc aggatacagt tacactgctt gacatcaaca
      781 actctgtacc gaaggatatg tacaaagagt ctatcgaagg caaatataac tacacactga
      841 aagatacatt catgggattc cattgtggaa atacagcttc cagcaagctt tccttctgtg
      901 agatgaagaa ccagatgatc atggcaagat ctcttccggt agaggttaca aacggaactc
      961 ttgaaggaga tatcgtacct ggagatatca cattctatcg tctgcagagc acagctgata
     1021 acaaactccg tggatatatt gcacatggtg aagttcttcc tgttgcaacg aaatcctttg
     1081 gttctatcgg tgtattcgct attccggaaa tgggacgttt ctaccgtcat gtactgatcg
     1141 agggaggata cccacatcac ggagcagtag cattcggaca ttatggaaaa gctctgtttg
     1201 aagtattcaa atacatcggt gttccggttg aagagattgg atacaaccag ccggcaggcg
     1261 taagataccc aacagagaat ccatggggct aatcagaatt caacagtatt gaatcaagat
     1321 tgaaaaaata atagactgac acgacaattt ataaggcatc ccgggggttt accctgggat
     1381 gtattagatt aaatgagtgt gagaaattaa ctttaataaa aatctgaatg aacttcatat
     1441 gaaagatacg aagatataat tgcctggtaa gagcaatctg gcgatttatt tcagataaac
     1501 gaacagcaat gaaatgcagt aatgcaataa agactaatag gagagaaaat tatgtattat
     1561 attggtattg accttggtac ttccgctgta aaacttcttc ttatggaaga ttcaggaaaa
     1621 atctgtaata ttgtttcaaa agaatatcca ttattcttcc cacatccagg ctggtctgag
     1681 cagaaaccgg aagactggtt tgcacagagc atggaaggta tgaaagaact gacaaaggat
     1741 attgacagaa ctaaggtagc tggaattggt tttggcggtc agatgcatgg tctggtaacc
     1801 ctggacaaag atgacaacgt aatccgtcct gcaattctct ggaacgatgg ccgtacaggc
     1861 gaggaaacag agtatctgaa tactgtgatc ggaaaagaga aactctctga gtatacagca
     1921 aatattgctt ttgcaggatt tacagcaccg aagattctct ggatgcagaa aaatgagccg
     1981 gagaatttca agaaagtagt taaaattatg ctgccgaaag attacctggc atatcgtctg
     2041 tctggttctt tctgcacaga tgtttccgat gcttccggta tgcttctgct tgatgtaaag
     2101 aaccgttgct ggtcaaagga aatgctggaa atctgcggta tcacagaaga acagcttccg
     2161 aaactgtatg agagctggga agtagtagga actctgaaac ctgaaattgc aaaagaactt
     2221 ggattctcag aagatgtaaa agttgttgca ggtgccggag ataacgcggc agcagctgtt
     2281 ggaacaggta cagttggtga tggacagtgc aatatttctc ttggaacatc cggaactgta
     2341 tttatttcca gcaagaattt tggcgtagat gaaaataatg cactccattc tttctgccat
     2401 gcagatggaa gttatcatct gatgggatgt atgctcagcg cagcttcctg taacaaatgg
     2461 tgggcagagg agattcttca gacaaaggat ttcgcagcag agcaggctcc gattcagaag
     2521 cttggagaga ataatgtgtt cttcctgcca tacctgatgg gagagcgttc tccgcacaat
     2581 aacccggatg caagaggtgt attcttcgga atgtccatgg acagcacaag agctgatatg
     2641 acacaggctg ttctggaagg tgttgcattt ggacttcgtg attctctgga agttgcaaga
     2701 agtcttggaa tcaagattga gagaaccaag atctgcggtg gcggagctaa gagcccactg
     2761 tggaagaaga ttattgcaaa cgttatgaac ctgaaggttg atgttctgga gaacgaagaa
     2821 ggaccgtcta tgggtggagc tatgctggca gcagtgggct gcggtgctta tccggatgta
     2881 gaaaccatcg gaaagaaatt tgccaaagtt gttgatacag tagaaccgga tcctgaattg
     2941 gttgcaaaat atgaagagag atatcagaag ttcagaactc tgtatccggc tatgaagcca
     3001 ctgttctaat cgaatatctg cttgataact ggggttgttg tactcattta gtacaataac
     3061 cccgttttga tatgtatggc atatcaggaa aagggcagct tgaggaattc tttcatggct
     3121 ctgctgatat agcggccttt cttccagtaa aaaaatacag tgcgtttact gctctgaccg
     3181 ggcagcttat aaaaaataag ttctgaattt gttggaactc tggagagcag aagatccccg
     3241 atgaaagtga tacccattcc caaacatgca atattatagg cagtcatctg ctgatccagg
     3301 cgaaatacca cagaaggtga aaagtgattt tcctgacaaa tggtcagtgc acgcttaccg
     3361 gtatcgttat ctgaacgaag aataataaag ggttcgtttt caaatttgtt taaaggaaca
     3421 gaaggaatat gagaagagcg gaactgaccg tttcggattt cctcaatagg aatctgatat
     3481 tcctgcagtc tggtatttac tgaataattt ttgggaactg caagaagaag ttgttctttc
     3541 tggtaggtat aatgttcaaa gatctggtta tccaggatgc agttatcgat caccagatct
     3601 aactttccgg cctggagaaa ctgggatagc tttgctgtac tttcttctac aagagaaatt
     3661 tgaacatggg gaaatttttg ggaaaaatca gcaataaggg gaggcagaat ccatgaagaa
     3721 aagaagttac tgccacctac attgagagtt cctgttttga gatttccaag atctaatagg
     3781 aaattttcaa gattattttc aatatccatg actttttcaa cagcctctat ataatgtttt
     3841 ccaacttcgg ttaactgcaa aggtttggta cttcgatcaa aaataggata accaatgcgg
     3901 ttttccacac gttttacatt tgcacttaaa gaaggctgcg aaatgaaaag ggcagcagca
     3961 gctttggaaa agcttttttc cttgtatact tcataaatat attccattcc ctgaaacata
     4021 tgatccctcc aatatataat ttagttactg ttcactctgt tcatagtaac ataatttaaa
     4081 cactatatat tttataaaaa tatatgtatt tgattatatt atagcagaga tatataataa
     4141 gggcaaatac atgggagggc gaataactat gaaaaaaata gactatcgtg tagaaaggga
     4201 ttctattggt gtaaaggata ttccggaaga tgtatattat ggagtgcaat ccttacgtgc
     4261 ggccgaaaat ttccacatta cggggctgaa tatgcatccg gaaattatta acagtcttgc
     4321 atacataaaa aaagcagcag cgataactaa ttgtgaagtg gggcttcttg agaagaaaaa
     4381 agcacaggcg attgtccagg catgtgatga aattgtttca ggaaaattcc ataatgaatt
     4441 tattgtggat cctgttcagg gaggagcagg cacatcttta aatatgaatg ccaatgaagt
     4501 aattgcaaat cgcgcaattg agatactggg aggaaaaaag ggcgattata caattataaa
     4561 tcctaacgat gatgtgaatt gtggacagtc taccaatgac gttattccta ctgccggtaa
     4621 aatgacttct cttcgtctgc tgcagaatct gaagaaacag cttcttcgtc tctacgatgc
     4681 tcttaatgaa aaagctacag agtttgatca cgtaatcaaa atgggacgta cacagatgca
     4741 ggatgcagtg ccgattcgtc tgggacagga atttaaggca tattcggtag caatcatgcg
     4801 tgatatccac agaatggata aagcaatgga tgagatgcgg acccttaata tgggaggcac
     4861 tgctattgga acaggaatta atgcagatga gggttatctg agaagaattg ttccaaatct
     4921 tactgaaata tcaggaatgg actttataca ggcctttgat ctgattgatt ccactcagaa
     4981 tctggatcca tttgtagctg tttccggtgc tgtgaaagca tgtgcggtaa ctctttccaa
     5041 aatgtcaaat gatctccgcc tgatgtcctc tggtcctcgt accggatttg gagaaatcaa
     5101 tcttccggca aaacagaatg gctcctctat aatgccgggt aaagtcaatc cggttattcc
     5161 tgaagtggtt aatcaggtgg cttttaatat tattggtaat gatgttacga ttaccatggc
     5221 tgcagaagct ggtcagctgg aattaaatgc ctttgagccg attattttct attgtatgtt
     5281 ccagtctatc gatactcttg gctatgcagt ccagacactg gtagataatt gtattgtagg
     5341 aattacagca aatgaagaaa ggtgccgtta tctggtagaa aacagtgtag gtattatcac
     5401 tgcgatcagc ccccatcttg ggtatcagaa ggctgcggat attgcaaaaa aggcaattaa
     5461 gacaggcgaa tctgtaagaa gtctgattct gaaagaaaag cttatggatg aggatgaact
     5521 caatcgtatt ctggatccga tccatatgac ggaacctggt atttccggaa aagattatct
     5581 tataaaaaaa taaagaaaaa aaacaggcgg gaaaatcttc ccgcctgtaa aatcgtctgg
     5641 acacatatca tatataaata tgatttttat atttttgaat tattcgattg atttcaaccg
     5701 gattagaaca gacctgtgat cttacctgtc tcgtctacat cgattctctc agcagccgga
     5761 actttaggaa gacctggcat tgtcatgatc tcgcctgtaa gagctacgat gaatcctgca
     5821 cctgcggaaa tcttcaggtt acgtactgta acttcaaagt ctgtaggagc acccagtttg
     5881 gtctggtcat ctgttaagct gtactgtgtc ttagctacac agatcgggca gttgccgaat
     5941 ccaagagctt ctaactgttt cgcctgtttc tgagcatttg ctgtcagaac aactctcttg
     6001 ccgccataaa ctttctgaac aatctggttc agtttgtctt cgatagaacc ttccagttca
     6061 tatgcatagg agaagtcgtt tggttcttct acaagacgga taacttcttc tgcaagtttg
     6121 attccgcctt cgccgccttt tgcccatact tcagaaagag caacgttaac gcccagttct
     6181 ttacatttag cttctacaaa gtcaagctct gcttttgtat ctgtagggaa tgcgttgata
     6241 gcaacaacac atggaagttt gtatacgttt ttgatgttgg aaacgtgttt taacaggttc
     6301 gggatacctt tttcaagagc ttccaggttt tcattgttga ggtcagcttt tgcaacgcca
     6361 ccgttgtatt tcagggcacg tactgtagct acgattacaa ctgcgcttgg ttttaaacca
     6421 gccatacggc atttgatatc aaggaatttc tcagcaccaa ggtcagcacc gaaaccagct
     6481 tctgtgattg cataatcagc aagcttcata gccatctttg tagctgttac agagttacat
     6541 ccatgagcga tgtttgcgaa tggtccgcca tgtacgattg caggaacgtg ttccagagtc
     6601 tgtacaaggt ttggtttcag agcatctttt aacagggctg tcatagcgcc ttctgcgtga
     6661 aggtcacctg ctgttacagg tttctgctcg gaaacttttc cgtatgtata tccgatgatg
     6721 atcttggata atctttcttt caggtctttg atgtcgcttg caagacagag aactgccatg
     6781 atttcagatg caactgtgat gtcgtatccg tcttcacgag gcataccgtt tgtctttccg
     6841 ccaagaccat ctactacgtt acgaagctga cggtcgttca tatctacaca tcttctccat
     6901 gtgatcttac gtgggtcgat gtttaatgca ttgccctgga agatatggtt atcgatcata
     6961 gctgccagta agttgttagc tgcgccaatg gcatggaagt cacctgtgaa gtgaaggtta
     7021 atatcttcca taggaacaac ctgtgcatat ccgccgcctg ctgcaccacc ttttacaccg
     7081 aataccggtc ctaaagatgg ctcacgaaga gctaccataa cgctcttgcc gagtctctgc
     7141 ataccatctg caagacctac agtagtagta gttttacctt cacctgcagg agttgggttg
     7201 atagctgtaa cgaggattaa ttttccatct ttcttgtcgc tttctttcag aagattgtag
     7261 tcgatttttg ctttgtattt tccgtactgc tccagatatt tgtcgtcaat acctgctttc
     7321 tctgcaatct gagtaattgg aagcatctcg cattcctgtg caatttcaat gtctgatttg
     7381 aatcccataa ttgtttttct cctttcgttt ccgcataaca tgaaaaactt ctgttgctgt
     7441 tcactccgcg atcagcaaca attattaatt gaaagaagta ttggccggtc tgcctggtat
     7501 tcctgatttc tgccctgaaa gttataaaaa aaggccagta tctgaatatt tcaaatactg
     7561 cccagacggt cggctcccac aaacctccga ctccacgtgg tttgcactcc actctttccg
     7621 tcagtactcg aaggttcttt caattgatga atacaatata tcattttgag aaaaaaatgt
     7681 caagaaattt ttgttgaaac gtcaaaaaat gtgagtaaac tggataaaag ttgtgcaaat
     7741 tgataagaga agagaatcgt aatccctggt aatgaaagaa aatacgtttt ctcaagggaa
     7801 gaaattgtta aaaaataaac atagtttttc ctgataaata agaaaatata aaaagcgggt
     7861 aaagactgtg caaaatatgg aaaatggaat tgacaacagt tcagaagata tgttattctc
     7921 atctttagta tgaaaagaca ctatcgtttt catgcaaata tttgctcaca ttcagagaca
     7981 gtttctgaat gttaagccat acggacaggc ggggcagttg ccgggtggga gacaccacat
     8041 tattgattga gttagaagct caaattttat aagttgatta ctttataata atcagtgcgt
     8101 aagcacacat catcttgtga aacggtcaat aagagcatag catatatttg ccagcgattg
     8161 aagacgacag cagtcatgaa tatttcagaa tacgggaaca ggcacaggat acagacggat
     8221 ttatacggga aatccggtca gtgtataaaa agacagagcc tgagaaattc tatagatcat
     8281 gagagaagca gatggtgaat gaacttatct gcttcttttt tgtgcagata tagcagatat
     8341 aaaggatatg gttggagata aacgctttgc ggggatgtgt agcgattcta tagaatcgtg
     8401 tgccgagtct cacatgcgtt cgacttgaat atatagagaa ataattgaat cattgtgccg
     8461 gttttgagcc agtatacaat tgctgtatga ttgaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccggagctt gcacagttgc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgctggac aatctctgcc atccggtttc ggtgatcaga gaagcggagg
     8761 agcttgcagc agatgctttt ggcgcagcac atgcatttct tatggtagga ggaaccacat
     8821 ctgcagtgca gagtatgatc ctttctgtct gtaaggcagg ggacaagatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg tggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgca cagctgggta tctcccttgg catggaggtc agccaggtgg
     9001 agaaggctat ggatgagaac ccggatgcgg tggcggttct tgtaaataac cctacctatt
     9061 atggaatctg ttcggatttg cggactatcg taaagaaggc tcatgccaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtatccg
     9181 gaatggcggc aggtgctgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agtgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggcactcagg ggagaggaat cctttgaaaa ggttgcaggg atggcgcagt
     9421 atgccagaga ggagatcaat gagatcggcg gctattatgc atatggtatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc catttataca ctgggaaatg
     9541 ggctggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccattgg agacaggctt caggatattg
     9661 agagactggt aggggcactg gctgatattg aacgtctgta taagaaggac agcacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacagg cggcaggcag gatcagcggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctggaga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gttgttccat gcagggaatg gaggatccga
     9961 aggtagaaca tcttcaggtt ctgaaagggg gtatctgatc atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttggaagat ttgtggctct
    10141 ggacggtgag atcgtatttt ctgacaagga tgaatttatt tatgatgaaa tggtcacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg attatcggtg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agtattgatg tggtggaatc
    10321 cgataaaatg tttgtggatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttataa ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gataatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggcggg gtagcttcag tggcaattcg caaatgctgt
    10921 cagaacagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaagatagat
    11041 gcggataatg cagcagaggt cgcagaattg atcagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctatgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggattatg atgagaaatt taagaaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgct tatgccctga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaatggc ggtgatcatg gatatccttt tgccacaaac
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct atgattttcc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa gaatattccg
    11641 ggagtacaga gaatccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaacgg acaggagatc
    11761 gtgccgatcc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttccg gctttgcgct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatagag gaactggatc gtatctgtga
    12421 ccatattatc tttaattcta cagcacagct gaagaaattt aaagaagtgt gtaccggagc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag ggggatcatg cgatctatga
    12541 tccctgtgcg ccgggttcca ggctgggggt taccagagag aactttgacg gggaatgtct
    12601 gaaatggatc gacggactgc attttcatac gctctgcgaa cagaatgcgg atgacctgga
    12661 gaaaacattg caggcggtag aggagaagtt tggagaattt ctgtctgagg tttcctggct
    12721 gaatatgggc ggcggacatc atattaccag agaggattat gatgtaaagc tcctggaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatgagat
    12901 cagaacgctg attctggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgtctgg caggagatgt gatcggagat tattcctttg acagagagat
    13081 ccggatcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaac ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taagagccgg ctttcctgat atctgccggg
    13261 ctatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcgcaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaaggtgtat atgctggttt cccaagctca gatggagaat gcaaagaatc
    13501 agcttggaaa tgtttccggt gtgactttgc tggaatgcga gacagatgat gcctgggcga
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggagga gactttgatg gactttaccg gaactgggag aaggacgata
    13681 gggtggctgc ctttatctgc aggactcttg gttgtccatg tctggatgcc agaccttttg
    13741 tgcttgaggg cggttccatc cattctgacg gagaggggac tctgatcgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaagacc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtctct ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccgg gaagatgtgg atggctttgt gtttgaagag ggagaagatg
    14161 aacgggaagc aggagaacgg atggctgcca gttacgtgaa tttctatatt tccaatggag
    14221 ggatcatcct tccacaattt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc tgaaagaagg atttatccca ttgatgccag agccatcatt gttggcggtg
    14341 gaaatattca ctgtatcacc cagcagattc ccggaaaaaa tatctgaccc tgatgcagaa
    14401 aactttgaga gtcatgtgtt tgagggttat tacctgaaag ttatgaaaaa acttacttat
    14461 gtaaacagga gcaggaggaa cagacaggat gagaaatgta acagtggcag cagttcagat
    14521 gaaatgcagt aaaagtgtgg agaaaaatat tgcccatgca gaggaactgg tgcgtcaggc
    14581 agcagcaaag ggagctgaga ttgttcttct tccggagctt tttgaacggc cctatttctg
    14641 ccaggagcgc agatatgagt attatgaata tgcgcagact gcagaggaaa accctgcagt
    14701 gcgtcatttc agcagggtag cggcagagtt ggggattgtg attccggtca gcttttatga
    14761 aaaagaggtc aataatactt ataacagcgt tgcggttctg gatgcagatg gaaagaatct
    14821 cggcatttat cggaaaacac atattccgga tgaccattat tatcaggaaa aattctattt
    14881 cacaccggga gatactggct ttaaggtttt tgataccaga tttggaacca ttggagttgg
    14941 aatctgctgg gatcagtggt tcccggaaac ggcaagatgt atggcactgc agggcgcaga
    15001 gcttctcttt tatcccactg ccatcggaag tgaacccatc ctggaatgtg acagcatgga
    15061 acactggaga agatgtatgc agggacacgc tgcctccaac ctgatccctg tgatcgctgc
    15121 caacagaatc ggtgaggaaa cagtagagcc atgtccggaa aacggaatgc agaaatctgc
    15181 tcttaatttt tacggctctt cttttatcac agacaacaca ggtgctctct gtgcagaact
    15241 gcccggaggg gaagaggggg tgcttgtaag cacttttgac ctggatgcat taaaggcaga
    15301 cagactgaac tggggacttt tcagagaccg cagaccggag atgtatgcaa aaattgtcgg
    15361 gaaatgatgt ataagtttag ttattgttca cacaccacta tcccgcgagg tgttttggca
    15421 tgaatatgcc aaaatcccga gacatacaag ccaaaattcc attgccgcag gcaatctgga
    15481 atgaattttg gctcagttac tgagaacgga gtgaacagta attgagttta taagaatttc
    15541 ataaaaagtt tatgattata ttagttgcta cctgcggtat atatggtaaa ataagagtac
    15601 gaacgttact gataacggag cgagcagtag agttttgaca tgtatttctg gcaaaatgga
    15661 gtgtagaaga tgaacagaaa agaatttttg gaaatcctga gaagccagct tgccggtcag
    15721 atgcaggagg gcaaagcagc agcacatatc aggtattatg aagattatat acagtctcag
    15781 gtacgtggcg gacgttcaga gcaggaagta ctgcaggaac tgggagaccc gcatctgata
    15841 gcaaaaactc tgatcgatac agatgatgga agtacacagg aagattacgg agagtattct
    15901 tcttacggaa gcagttatgg caatgagaca gagcttcctc atcagcagga gaaaagatgg
    15961 aaaaaagtaa tcgatctttc tacctggcat ggcagggctg ttgttattgc agcggcggct
    16021 gttataattg ttttactgat actgataatc ggagttgcga ttccgttttt tattattctt
    16081 gcaattattc tttattttct ttcatggctg aagaaaagaa atgatcaatg aaaatctgtg
    16141 cagggtttca gaaaagaaac cctgcgcaga atcttaaaaa tcttaagtgt aaacgttctt
    16201 gtttcacgat attaattccc cttgaatatt tataatcata caatctcaac ttatttctat
    16261 tctttaatcc tgccaggtgc agggaaaaat cccacattca tttttatatt ttttgttcgg
    16321 aaaggagacg gaaaatgaaa cacaatttca aactgaaaga acgccttgga gctttgctgc
    16381 ttgcaatgct ttttattctg caggcaattc tggggcttgt gcctgtctgc gtaactcagg
    16441 cggcaccgtt aactgtagaa acatgggaca gtgacaaggt ggtagattat ggttatcgct
    16501 ttaacatgaa gtttcagccc ggaattacca catatgaatc ttttgggtgt gataatctgg
    16561 acagggaagc tttttcagac aatggaaaaa gcgaacgtga tacagagtgc gttcgtgtag
    16621 gagcggacta taaagccgga agcgcaggga tgcgttataa caatgtagga aaagatggaa
    16681 atggaaatat tgttgatgtc agactcattc ttgtgggagt agagaatgca gaaccccgtt
    16741 atgatctgcg cactgcagaa tcgattgttc agaataaagg cggagctacg tttgcatgga
    16801 aagataatga agcttatcca atggttggct tttccaaaaa cagtatcggt gtatttattt
    16861 attctgtagg atacgcaaag gttaagtttc agtttctgaa gcatggaaca gaagaaacac
    16921 tgccgatcag tggccatgga accatacgtg atattgatgc gggacaggga gttcgtattc
    16981 cgtcagacag cagtctggat aatgcatatg ttctgaaaaa caatgattat ctgacggtag
    17041 atggaaattc tgtaagctca ccccttggtt ccgttgagcc ggatgatccg agaggatggc
    17101 tgaatctttt ttatgataca gataatttta cggtagaatt ctgtcatcag ttcagactgg
    17161 ataaatggga taaaagtcgt gaagatgcca ttgcaaaagc cggttctcag gaaagatggg
    17221 cagagattac aagaaataaa tatctggatc catcaggcaa cagttattgt ccgaacttta
    17281 aaggacagaa atactgcaaa gcatatgcat attttgattt tacatcctat tgtttcggtg
    17341 atgttgagat gaaaaaagcg cctgagaaac gtgtgggaga ggcaaactgt acatgggaac
    17401 aggcagctgc cgcatcaaaa gaaaaacctt ttggcattcg tcagggacag gaatttcagt
    17461 atatgatccg ggcagaggtg acacccaata gactgaaatc ctttgtggta caggatatac
    17521 ttgaggattg tcttactata gaggatgcat caaaagtcag tattgtgaat gatgcagggc
    17581 agacagtgac agactggttt gatgttgctg ttgaaggaca gaaagtgacc tgcagggcca
    17641 aagcagagag ccttcaggat gaagcattta cagataatca gacttacaca tttactttaa
    17701 aagtacgcca gagaccggaa tcagaaatta acatttcaaa ataccttgca gaggatggat
    17761 acagtattct tgtaccaaac catgcatcca tgagttatga acgtacaaac ggaagcggag
    17821 atacaatgga tacggaaaca gtgtgggtaa agggtgtgat tccaccggaa ctggaagtaa
    17881 agaaaaatac ttctcagtat gaatggaaaa cgggagatat catagattat gaggttctgg
    17941 tttctcagac aaaacaggat gtaaaagcag taaatgttgt tattacagac gagcttccat
    18001 catgtctgca gcttctggaa gggcagtatg ctgtagagac aagtcaggga ggcgagaact
    18061 gtacgcttac cggacaggga gaaaatggat ggaaagcaga gtgtccgtcc ctgaagtatg
    18121 gggagacgat cacaatccgt tttaaatgtc aggcatctgc ggattccaat ggacaggaat
    18181 gggaaaatat tgtgactgca acagcggata atctgatcaa tcctgacaca ggagaacagg
    18241 aatccagaaa ggatatggca gaagtatggc cgaacagtcc acagcttgaa attgataaaa
    18301 cagcagacaa atatgaatgg caggcaggag agcaggtagc ttaccggatc gtagtgaata
    18361 atgtaacggc aggaacaatt gcaaaagatg taactattac tgatattggt ctgccgcagg
    18421 gactggttct ggcaggtggt acacagagca tggaagtact gggagttcag caacaggtaa
    18481 actatcccgt accggataag aaaacaggac aggcatatga agcgagacct gtggattctc
    18541 agttgaatgc agatgagaac ggattttcct tttattgttc ttatgtacca tacagtcagc
    18601 ctgtaacgat tattttccat tgtatcgcac aggaagaggc aaatggacac gaaagcgtaa
    18661 atgcagcaac tgtaaaagct gctaatacag atgagagatc tgatgatgca gaagtatatg
    18721 taaattcagg agaattctgg attgagaaat ctgcagatca ttatgaatgg caggtcggag
    18781 aacaggtaca gtacaatgtg gtggtggaga ataaaaaagc aggtacagtg gcccggaacg
    18841 taactgtctg ggataccggt atgccggcag gacttgcgct ttcatcggca gaggatgtat
    18901 cggtaagcgg aatcccacag aatattacgc agctgacagc agggaccaaa gatgttttga
    18961 accagctcaa tccggaattt tataatgaga catcagagaa accggtgaat tatgaatttc
    19021 ttcaggaggg aagcggatgg agactgaaca tttcagatct tccggcaaat actccggtta
    19081 tgatttcttt cctttgcaca gttacggaag cggcaaatgg aatggaaagc attaatgttg
    19141 ccaatgtgca ggcgcagaat gcccctgttt cgcaggatga tgcagaagtg tatgtaaata
    19201 cggcagttct ttctattgag aaaagttttc agaatccata tctggcagcc ggggacggac
    19261 gtgcggaaaa tgaatttcgg gtaggagaac aggtgaatta tcaggttacg gttaataatc
    19321 ttcagaaggg atctatcgca agaaatcttg tgatcagtga tctttctctt cctgaagggc
    19381 tggctctgga cggagctgaa gatgctgtta ctgtaagcgg tgttccggct gttattcaga
    19441 atccggtggc aggaattgat gatgcaggaa atcagctgaa tccggaaaat tataaagaaa
    19501 cagtggaaaa accagtcagc tgtcaggtta cacgtcagga aaccggatgg atcgtgacga
    19561 tttcagatct tccgtatcag acacctgtga ctgttaattt ccgctgtact gcgcaggaaa
    19621 gcgtaaatgg gatggagatt gtaaatacag cacaggcgta tgcagataat gcacagaaag
    19681 taaaggactc ctcaaaaatc tgggtgaact cgcctgttct taaagtagag aagacgacgg
    19741 acaaaccatt ttacaaatat ggtgatatta ttacataccg cattgtcctg acacaggagc
    19801 agaccggatg tgtggcgcgt aatgttactc tgcaggatgt gatcgatact cagggagtac
    19861 gtcttctgaa ggattcggtg attctgatgg atgagaaagg aaatgtggca gatgctgatg
    19921 tacagatcaa tgatgataat actttcctga tgtcaacagg caggacactg gtcagggata
    19981 gcagatatag tatctgcgat aatgataaag gcggtctttt tgagcaggta atgtataatc
    20041 ctctggactg tcaggaacag aaaagtatga tcgtggaata tcaggcagca gtgattgatg
    20101 cagccctggc aggacagaaa gtgcacaata ctgcagttgc agacagcagt gaaaagatac
    20161 ctgcaaccgg ggaagcagag acagaggtac acagtccgat tctggaaatt gtgaaggaat
    20221 cagataagaa agagtatgcg tccggtgaaa aaggatacta taaactgaca gtaagacaac
    20281 tgcgtgagga tgtcacagat cagaatattg ttatcgaaga taaactggaa acccaagggg
    20341 cttccattgt aaaagacagc atttttgtga agaaaaacgg tatagaactg aaagatgcca
    20401 aaatagaggc agatgataca ggatttgtaa ttcagacagg agcatcgttg tcagatatgg
    20461 ataaaattga agtctgctat gaaatggtat ttaaaacaga aagcacagag cctgaaaaaa
    20521 ttgtaaacac agcgaaagca agaggtgata tttcaccgga aattactgca cagcaggagg
    20581 catatgtgaa agcaaaagca gaaccgactg ccacaccaac accgtctgca acaccgaaac
    20641 caacagaaac accaaagccg acagagacac caaaacctac agaagtaccg aaaccgacgg
    20701 agcagccaaa agccacacca acaccatctg taccgggaac ctgcccgaaa atgactcctg
    20761 taccgacgaa agcaccgtta gcatcttaca atggtggaaa taatggaggc acgacttccg
    20821 gaagcggagg cagcagttac gcaaattcgg gtggatattc cggtggatac ggaagctatc
    20881 agggtggttc catggcagga agttctaaaa caggagatgt cagaccgttt aaaatgatgg
    20941 ctgttcttgg ccttatcgga atgggactgc tgacaggagg tgtggtgatc tacagaagaa
    21001 ctgtttccgg gaaaagaaat ataaagggta tgccgcggaa atgaaaaaac tcagaacatt
    21061 tgcagtaagt atgatcatag cagcaattgg gcttcttata tattgtgccg gtttctatat
    21121 aaaaagttat gaacagaatc ttgcagcaag gcaggaatat gcagagcttt cccaaatggc
    21181 aggggtgaag aacagagaag gtgccggatt attggcagat ggcaaaaaaa ctgatgaaga
    21241 cagcagtaca aaaaacagtg aaaaaaaacg caggaaaaaa cagagaagat cttctgaatc
    21301 aaaaaacaaa aactgtacag atgaaatcag ggaatccttc gggatttcct gggaaaattt
    21361 aagaaagatc aactctcaga cagttgcctg gattactgtc ccgggagccg atatttctta
    21421 tcctgtagtt caggcggcgg atgatgaata ttacctgaaa cataatttca gaggagagga
    21481 agatctgttt ggatgtattt ttctggaaca tgacataaaa aagaatttta cagattccca
    21541 cagtattctt tacgggcata atatagaagg taatatgatg tttgcaaatc tgaaccgtta
    21601 tgaacagcct gaatttctga aaaaatgtcc tgaaattgag atcacaacac caaaaagaaa
    21661 gtttctgtac aaaatttttt ctgtggaaca ggcatcttcc aaaagcccgg catttgaata
    21721 tggatacaag ttatccagtc ctgcatacag gagacaatta tctatattga aaaataattc
    21781 catgtatgac acaggagtag agcctgatga aagggagaga atggtgactc tgatcacctg
    21841 taattcacgt ctggataaag aaatacgtat ggcggtacat gggatttgcc atgaatgtta
    21901 tggtatagaa aaagctgagc cgaagtgatg ttgaaatcaa tcggatattg gtaactttcg
    21961 taaaggatga actgttactg ttcacatatc actatccctc gaggtgtttt ggaaaaaact
    22021 aatgaaaaat ctctcgatat tttgtataat ttatgcataa aaaacaactt gttcgtacgt
    22081 gcgtacaagt tgtatcctaa atacaggagg gaagaagaca tgacagataa tggaaagccg
    22141 aaatatttct cactgatgga acagctcaga agtgatatta tgtcaggagc tatccgaccg
    22201 ggagagaagc ttccttcaga aaacgagctt tcacagaaat attccctgag tagacataca
    22261 gttcgtaaag cactgggaat cctggagcag gacggatatg tagaggcatt tcacggaaga
    22321 ggtacttatt gctctgagaa tatgcgccat ataaagaatt caaagaatat tgcggtagtg
    22381 accacatata tttctgatta tatttttccg agactgatac agggaatgga taatgtcctt
    22441 tcagaaagcg gttacagtat tatcctgaaa aacacagcaa acagcagaca gaaagaggcc
    22501 agatgtctgg aggaacttct gaagaaagat attgatggac tgatcattga accaagcaaa
    22561 agtgagatga tctgtaaaca cagaaatctt tatcagaatc tggataaatt tgaaattccg
    22621 tatgtgttta ttcagggaat ctattcagaa atgagggata aacctcatat tcttatggat
    22681 gatgcacagg gaggctatct tgtaacaaaa tatctgctgg aactgggaca taaaaagatc
    22741 aagggtttct ttaaggcaga cgatatgcag ggactggagc gccacaaggg atatgtgaag
    22801 gccttacagg agtcagggat tgcctatgat cccgatgatg ttgtctggtt tcatacagag
    22861 gacaggaaag taaaacctgc actgatggca aaagaaatgg tacagagcgg acagcttccg
    22921 gatggaatcg tctgttacaa tgatcagatt gctgttcagg ttatggaaga actggagaaa
    22981 atgggagtca ggataccgga tgatatttcc attaccggtt atgacaattc actgtatgct
    23041 cagcgaggaa gcggaatcac aacgatagct catccgcagg aaaagctggg agaaatggca
    23101 gcagagctta tacttgagaa gatcaacgga gttcctgaag aagaaagtaa ggttgaaaga
    23161 ctgatttatc cggaactgat catacgggga tcatgcagaa aaatattgta aacaaatgaa
    23221 ataaataaaa aataaaaata aatccagga
//
