LOCUS       c00004_gnlPro..        13220 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IKGLIOCC_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 18:15:16
            Original ID  :: gnl|Prokka|IKGLIOCC_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 165998
            Orig. end    :: 179218
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13220
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[175998:178990]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12992
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13220
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13220
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(811..1785)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_150"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.1e-39,
                     bitscore: 129.3, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVKVSVILPVYNVSEYLRQCMDSIVGQTLKDIEIICVDDGSTDD
                     SLEILKEYEAKDKRVKVIEQKNAGAGAARNNGLAIATGEYLSFLDSDDFFEPDMLEKAY
                     EKGKSSNAQVVVFRSDQYREDLNEFVQVKWTLREKQIPPYRPMNCRSFTGNIFKVFVGW
                     AWDKLFERKFVEENHLKFQQIRTSNDMLFVFSALAFAQRMEIVDLVLAHQRRNNPNSLS
                     NTREKSWDCFHTALNALKDALTAHGNFWEFEQDYINYALHFSLWHLDTITGAKKEVLFN
                     KLKNEWFAEFGIDSLPAERFYDKKEYAKYLKIKSNEFNAYYEE"
     CDS             complement(1796..2944)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_151"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6.2e-33,
                     bitscore: 107.3, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKVSIIIPTYNVEMYLVECMESVVNQTLKDIEIICINDGSTDGS
                     LEILKSYAQKDDRIVLVDKENGGYGIGMNIGLDKATGEYIGIVEPDDFIPLNMYSDLYE
                     KAVENDLDFIKADFYRFKRDSETEDMELVYNHLSPNKEDYNIVFNPSETPKAIRYIMNT
                     WSGIYKRSFIEEFHIRHNETPGASFQDNGFWFQTFAYAKRGMIIDKPYYMNRRDNPNSS
                     VHNKEKVYCMNVEYDHIRELLVRDKEVWERFRSMYWLKKYNNYMGTIKRIGEEYKREYV
                     HRFSDEFKRGLELGELDESVFTKISWSNIQFITKDPNGFYMKKVATPVKVRRLTKKVEK
                     LEKQNAKLQNDIKIIKGSRSYRLGWFMLTIPRKIKALFKGNK"
     CDS             complement(2959..4065)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_8"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_152"
                     /sec_met_domain="NAD_binding_8 (E-value: 8.8e-21, bitscore:
                     67.3, seeds: 167, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKYDYLIVGAGLFGAVFAHEMTKEGKKCLVIDKRDHIAGNIYCE
                     NVEGINVHKYGAHIFHTSDKVVWEYINQFAEFNNYINSPVARYKDELYNLPFNMNTFSK
                     MFGIKTPAEAKAKIQEEIEELGITEPKNLEEQALSLAGRSVYEKLVKGYTEKQWGRDCK
                     DLPAFIIKRLPLRFIYDNNYFNDRFQGIPMGGYTAIVEKMLEGSDVLLNTDYYEFRKEN
                     AGIAEKTVYTGMLDKYFDYKYGVLEYRSVRFETETLDMDNYQGNAVVNYTEREVPYTRI
                     IEHKHFEYGTQPKTVISREYPSEWKLGEEPYYPVNNEKNEEVAGKYRELADKEENVIFG
                     GRLGEYRYYDMDKVIAAALKAVEKEKNN"
     CDS             4259..5497
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_153"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 2.6e-34,
                     bitscore: 111.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 1.6e-29, bitscore:
                     95.3, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSYKIAIAGTGYVGLSNAILLSQHNEVYAVDIIEEKVNLINSGK
                     SPIVDKEIQEYLATKDLNLTATTDAKKAYENADFVIISTPTNYDPKMNYFDTSSVEAVI
                     KLVLEYNPNATMIIKSTVPVGYTLSVREKFNTENIIFSPEFLREGRALYDNLYPSRIIV
                     GAPLDDERLVQAAHTFAGLLKEGAIKEDIPVLFTNPTEAEAVKLFANTYLALRVSFFNE
                     LDSYAEVHGLNTKQIIDGVGLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYKDVPENL
                     IEAIVKSNSTRKDFIADRILEKAGYYHGTAGRDGTPGNQVTIGVYRLTMKSNSDNFRQS
                     SIQGVMKRLKAKGAEVIIYEPTLADDTFFGSKVEKDFDAFKANCNVIIANRFSDELADV
                     EDKVYTRDLFRRD"
     CDS             complement(6203..7555)
                     /locus_tag="ctg4_154"
                     /transl_table=11
                     /translation="LSYTWYEVFWFFLLYSFAGWVIGTSGAALKEKKFIDVGFLFGPWC
                     PSYGFGAVGFALFLPELKDQPVFLFAGGVILSFIITSFTGVTLERIFHQKWKDYSRRRF
                     NFGGYVNLPYTVVWGAAALLCIWIVNPFLSKIIEILPYGLGKVILIIVYIVIVIDFIGT
                     ISGILSVHIRLARLGKLVLVEEVADNLQKAADYMGNGLTGWVLKHLEKSHEGLEIKEII
                     RSKLQRREKAQEMTGVFAAGCGFYKLFWLFFLGSFLGDITETIFCWWKMGTITSRSSVV
                     YGPFSLVWGIGCFFLTYMLYQYRDRSDSFIFIFGTVLGGAYEYICSVVLELVFGTVFWD
                     YSKIPFNLGGRINLLYCFFWGIAAVVWMKILYPKLSDFIEKIPKKIGVPLTWFLVVFMV
                     FDMGISGLALNRYHERHQKAATPENAITKILDTRFPDKRMERIYPSAKHVK"
     CDS             7620..8381
                     /locus_tag="ctg4_155"
                     /transl_table=11
                     /translation="VNPPNAILHELLNLAEIMLTNGAEVSRVEETLNRMGHAYGATQMN
                     VFAITSSIVVTMVFEEGEEYTQTRRITTPVGTDFFKLEQANALSRRCCSSPLSLPDLKD
                     EINKISKISPAPYTIYLGSMLGAGGFSVFFGGTILDGAIAVIFAFLLCFLQRHLNSICS
                     NTLILQFFCSLFVGSGICVAAHFFPVIHADKVMIGDIMLLIPGILMTNSIRDILIGDTI
                     SGVMRLVESLLWAGALACGFMCAIWFVGGVL"
     CDS             8378..8812
                     /locus_tag="ctg4_156"
                     /transl_table=11
                     /translation="MILQFFAAFIGAAGFGFLFHLQFKHIFPAALGGVLTWVIYVIATT
                     WGFDVFISSLFASAFAAIYSEVIAKIRKAPTTLFLIISVVVLIPGGSLYYTMSYAVQKK
                     WAEAAAYGSQTLQCALGLAIGMSLIWIFHDMARKVYYLIH"
     CDS             10001..12253
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_157"
                     /sec_met_domain="Gly_radical (E-value: 2e-41, bitscore:
                     134.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 4.6e-266, bitscore:
                     877.2, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQKEQWQGFNGRIWREEINLREFIQDNYTPYDGDASFLEGPTEA
                     TDTLWGELQKLQKAEREKGGVLDMDTDIVSSLTSHKPGYISESLKEKEQIVGLQTDKPL
                     KRAFMPFGGIRTAEEACTTYGYTPNPEFHKIFTDYHKTHNQAVFDSYTPEMKKARHNKI
                     ITGLPDTYGRGRIVGDYRRVALYGIDLLVADKQKDFANCGDGTMTDDVIRLREEISMQI
                     KALKDMKVMAESYGYDISEPASNAKEAVQWTYFGYLAAIKTQNGAAMSIGRIATFLDIY
                     IKRDMDKGILTEKEAQELIDHMTMKFRMVKFGRIPAYNQLFSGDPVWATLEVGGLGQDG
                     RSMVTKTDYRFLHTLENMGPSPEPNLTVLYSERLPKAFRDYAAHISITTSSIQYENDDV
                     MRPVWGDDYSICCCVSATQTGKEMQFFGARANLAKCLLYAINGGVDEKTGQQVGPEYKP
                     ITSEYLDYDEVMHKYDIMMDWLAGLYVNTLNLIQYMHDKYYYEYALMALIDTNVRRTFA
                     TGIAGFSHVVDSLSAIKYAKVKTVRNEEGLVVDYETTGDFPKYGNDDDRADDIAVWLLQ
                     TFMKKLEKFHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQ
                     NGLLASLNSVAKLPYEWALDGISNTQTINPDALGHSEEERINNLVNVMDGYFAQGAHHL
                     NVNVFGVEKLIDAMEHPEKEEYANFTIRVSGYAVKFISLTKEQQLDVIARTCHDRM"
     CDS             12225..12992
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.7;
                     E-value: 2.9e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_158"
                     /sec_met_domain="Radical_SAM (E-value: 1e-30, bitscore:
                     100.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPEHAMTECNKNAMALVHSTESFGSVDGPGVRFIVFLQGCPLRCQ
                     FCHNPDTWKMTEENGAVWRSADELLNQALRYRTYWKNSGGITVSGGEPLLQIDFMLEFF
                     KKAKEKGIHTVIDTAGGPFTREEPFFSKFQELMKYTDLLLVDIKHIDTECHKTLTGRSN
                     ENILDMIRYLSDIKKPIWIRHVLVPERSDKDEYLTRLADFIHSLDNVEKVEILPYHTMG
                     IYKWKELGLEYPLEGIEPPTKERVENAKKILAI"
ORIGIN
        1 ttctgttttt catcttctaa tatctgcatt aaacctctaa cgacctccaa ataggattca
       61 aaacgaattt ttctttttcc accggtcatt atcgaattgc ctctaactcg tcttaagtat
      121 aaattatctc tgacacatct tgctctggct gctttaatca tagttcttac agtatataga
      181 ttatcctcaa aatacctttc ttccccaaat ttgatattat tatctatcag aaattgccga
      241 cgcacaaatt gtaaacaaac tgacatttta atatcgcctt tattctccat ctcaatgtac
      301 agatttttac catcataaac accatcatac tctttatgtc tatgatataa tgtaagaaat
      361 tgaggaaatg cttcctcaat ttcttttgat tcgtaaaaac tttctgcctc aaaatacaga
      421 atatccagac tatctgcttc tgcatattga tacaatgtct ccagacagtt ttctttaatc
      481 aaatcatcac catccaaata gtagatatac ttgccccgag cacgctgaac acccttattt
      541 ctctggtacg caactccgtg gttttctccc gtaaacactt gaatatatgg atataaactc
      601 tgatatttat ttaatatttc taaagttcca tctgttgaac catcatttaa acaaataatc
      661 tcgtaattct taaaactctg atttaacaca gattttaatg tttcttccac atattgtcct
      721 acattataac aaggtattat cactgaaatt ccatactctt ttttatcggt actcatcgct
      781 gtctcctttc tgtctatcta ctcacaacgt ctattcttca taataagcat taaactcatt
      841 tgattttatc ttaagatatt tggcatactc tttcttatca taaaatcttt ctgctggaag
      901 agaatcaatt ccaaattcag caaaccattc attctttaat ttattaaata aaacttcttt
      961 tttcgctccc gttatcgtat ctaaatgcca taaactaaaa tgtaacgcat agttgatata
     1021 atcctgctcg aactcccaga agtttccatg cgctgtcaac gcatccttta atgcgttcaa
     1081 tgcagtgtgg aagcaatccc atgacttttc tctggtatta gagagagaat tcggattatt
     1141 cctccgttga tgtgccagaa caagatctac aatctccatt ctctgtgcaa atgcaagcgc
     1201 tgaaaataca aataacatat catttgatgt tcgaatctgc tgaaacttca gatgattctc
     1261 ctcaacaaac ttgcgctcaa acagcttatc ccaagcccat ccgacaaata ctttgaatat
     1321 atttccggta aaagaacggc aattcatcgg acgatatggc ggaatctgct tttctcttaa
     1381 ggtccactta acctgaacaa attcgttcag atcttctctg tactgatctg aacgaaatac
     1441 tacaacctgt gcattagagc ttttgccctt ttcataggct ttttctaaca tatccggctc
     1501 aaaaaaatca tcggaatcaa gaaaagataa atattctccg gtagcgattg ccaaaccatt
     1561 atttctggca gctcccgctc ctgcattttt ctgttcaatt actttaacac gtttatcttt
     1621 tgcttcatat tcctttaaaa tttctaaaga atcatctgtt gaaccatcat ctacgcaaat
     1681 aatctctatg tcctttaacg tctgtcctac aatgctgtcc atgcactgac gaagatattc
     1741 agacacatta taaactggta atataacaga tacctttacg ctcataattt ctcctttatt
     1801 tattgccttt aaaaagcgcc ttaatctttc ttggaattgt taacataaac catccaagtc
     1861 tgtaggatct ggaaccttta ataatcttaa tatcgttttg aagttttgcg ttctgttttt
     1921 ctaacttttc tactttctta gtgagtcttc ttacctttac cggagtagcc acctttttca
     1981 tatagaagcc attcggatcc ttggtaataa actgaatatt agaccagcta atctttgtaa
     2041 atacggattc gtctaactct cctaattcaa gtccccgctt aaactcatca ctgaaacgat
     2101 gaacatattc tctcttatat tcttcaccaa tacgcttgat cgttcccata taattgttat
     2161 acttctttaa ccagtacatt gaacggaaac gctcccatac ctctttatct ctcaccagca
     2221 actctctgat atgatcatac tcaacattca tgcagtatac cttttctttg ttatgaacgg
     2281 aagaattcgg attatctctt cgattcatat agtatggctt atcaatgatc attccacgct
     2341 ttgcataggc aaatgtctgg aaccagaatc cattatcctg gaaagatgca ccaggagttt
     2401 cgttatgacg aatatggaat tcctcaataa agcttctctt ataaattccg ctccaggtat
     2461 tcataatata acggattgct ttcggtgttt cacttggatt gaacacgata ttataatctt
     2521 ccttatttgg tgataaatga ttataaacta attccatatc ctctgtttca ctgtctcgtt
     2581 taaaacgata gaaatctgcc ttaataaagt ctaaatcatt ctcaacagct ttttcatata
     2641 aatcactata catatttaac gggataaaat catctggttc tacaattccg atatattctc
     2701 cagtcgcttt atctaaaccg atattcattc cgattccata accaccattc tctttatcaa
     2761 caagaacgat tctgtcatcc ttttgcgcat aactctttaa gatctctaaa gagccatcgg
     2821 ttgaaccatc gttaatacag ataatttcaa tatcttttaa tgtctggttt acaacactct
     2881 ccatacattc tacaagatac atctccacgt tataagtagg tataataata gatacttttg
     2941 ccatttcctc actcctaatt aattattctt ttctttctct actgctttta atgccgctgc
     3001 aattaccttg tccatatcat aataacgata ttcgccaaga cgtccgccaa aaataacatt
     3061 ctcttcttta tctgctaatt cacgatactt accggcaact tcttcgttct tctcattatt
     3121 caccggatag tatggttcct caccaagctt ccattcactc ggatactctc ttgaaataac
     3181 tgttttgggc tgtgtaccat actcaaaatg cttatgctcg ataatacggg tataaggaac
     3241 ttctctctct gtatagttta ctacagcgtt accctgatag ttatccatat ctaatgtctc
     3301 tgtttcaaag cgaacgcttc tgtattctaa tacaccatat ttataatcaa aatatttatc
     3361 aagcattccg gtatacactg tcttctctgc gatacccgca ttctcttttc taaactcata
     3421 ataatctgta ttcagcaata cgtcagaacc ttctaacatc ttctcaacaa ttgcagtata
     3481 tccacccata ggaattccct ggaaacggtc attaaagtag ttattatcat aaataaaacg
     3541 aagcggaagt ctcttaataa taaatgcagg aagatcctta cagtcacgtc cccactgttt
     3601 ctctgtataa ccctttacta acttctcata tacagaacgg ccagctaaag aaagagcctg
     3661 ttcttctaag ttctttggtt ctgtgattcc taattcttca atttcttcct gaatttttgc
     3721 ttttgcttct gccggtgtct taataccaaa catcttgcta aatgtattca tattaaatgg
     3781 taagttataa agttcatctt tatatcttgc taccggagag ttaatgtaat tattaaactc
     3841 tgcaaactga ttaatgtatt cccaaactac tttatcagat gtatggaaaa tatgagcacc
     3901 atacttatgc acattaattc cctctacatt ctcacagtaa atattacctg ctatgtgatc
     3961 tcttttatca attacaagac atttttttcc ttcttttgtc atttcatgag cgaaaacagc
     4021 accaaaaagt cctgctccta caatcaaata atcatatttt ttcatgattt ctccttttac
     4081 atttttctcc aaaaaatatt gttctgtaat atatccgtaa tattttaaca tgatataaca
     4141 tttttttcaa ttgacaaacc tcttaaataa tcttatgatg tacattcttt tcttgacttt
     4201 ttaacacact ctgtttacaa ttttactaaa taatgttcaa taaaggagtg tattattaat
     4261 gagttcttat aaaatagcga ttgccggaac cggttatgtc ggtctttcca atgcaatcct
     4321 tctttctcag cataacgaag tttatgccgt tgatattatc gaagaaaaag taaatctgat
     4381 caattccggc aagtctccta tcgtagataa agagattcag gaatacctcg ctacaaagga
     4441 tttaaatctt acagctacta ctgatgcaaa aaaagcttat gaaaatgcag attttgttat
     4501 catcagtact cctacaaact atgatcctaa gatgaattac tttgacactt caagcgtaga
     4561 agctgttatc aagttagttc ttgaatacaa tccaaacgcg actatgatta tcaaatccac
     4621 tgttcctgtt ggatatactc tttccgtaag agagaagttt aacacagaga atatcatctt
     4681 ctccccagaa tttttacgtg agggacgtgc tctttacgac aatctctatc cttccagaat
     4741 tattgttggt gcaccgttag atgatgaacg tcttgtacag gcagcacata cttttgccgg
     4801 tcttttaaaa gagggagcta tcaaagaaga tattcctgtt ttatttacaa accctacaga
     4861 ggcagaggcc gttaaattat ttgccaatac ttatctcgca ctccgcgtaa gtttctttaa
     4921 cgaacttgac agctatgcag aagtacatgg cttaaataca aaacagatta ttgatggtgt
     4981 tggtttagac ccacgtatcg gtacacatta caataaccca tcttttggtt atggcggata
     5041 ctgccttcca aaagatacaa aacagcttct tgccaactac aaagatgttc ctgaaaactt
     5101 aattgaagcg attgtaaaat ctaactccac aagaaaagat tttatcgctg acagaatctt
     5161 agaaaaagcc ggatattatc acggtactgc cggacgtgac ggcactcctg gtaatcaggt
     5221 taccatcggt gtataccgcc ttactatgaa gtccaactcc gataacttcc gccagtcttc
     5281 tattcagggt gtcatgaagc gcctgaaagc taaaggtgca gaagttatca tttatgaacc
     5341 aactttggct gatgatactt tctttggaag caaagttgaa aaagattttg acgctttcaa
     5401 ggcaaactgt aatgttatta ttgcaaatcg tttttccgat gaactcgctg atgtagagga
     5461 caaagtttat acaagagacc tcttccgaag agattaaatc ctgatttgtg aggctacgaa
     5521 gcagacgaac tccagaagcc aaaataaagc atatttgtga ctttagtcgc ggcagtttga
     5581 atgttcgctt aaagcgctca catccaaacc ttgctccgag gccacaaata tgctttattt
     5641 agcttctgga gttctgtgtg ttggcaactc agaaaatcag ttggagggat ttggagaaga
     5701 aggttgaagg tatagaaata tccagaaaat taaattctat aggattgata cataaactat
     5761 tatcatagta atacaataat ttatgggtag gttactactt tcttatgaac tggaaattta
     5821 aaactgttta tagctttatc tcttaaaaag tgagatgttt tcattgaaaa cgcgaaaaaa
     5881 aactacaaaa aaactgtaaa aaacaaataa atttttaaat caattccagt aatggtttaa
     5941 acgtcagttc tttagaattt taactcctcg gaatgccata accatctgac gcccctcaaa
     6001 tctctccaaa aataaattct gaatttactt aggcagccaa aacacagccc acagggaata
     6061 taatatccta tatttgtggc ctcggagcaa gtgttggata cgagcgaata gagcgagtat
     6121 tcaacatgcc gcaactaaag tcacaaatat aggatattat attccctgtg gacgtctcct
     6181 ttgctacgca aatcagaatt ccctacttca catgtttcgc acttggatat attctctcca
     6241 ttctcttatc tggaaatctc gtatctaata tcttcgttat agcattttcc ggtgttgctg
     6301 ccttctggtg tctttcatga taacggttta atgcaagtcc tgagattccc atatcgaata
     6361 ccatgaatac aaccaagaac caggttaatg gtaccccgat tttctttggt atcttctcaa
     6421 taaaatctga tagtttcggg tataatattt tcatccaaac tacggctgcg attccccaga
     6481 agaaacagta caataagttg attcttccac ccagattaaa tggaattttg ctgtaatccc
     6541 agaatacggt tccaaagaca agctctaata cgacactaca tatatattcg taagcaccgc
     6601 cgaggactgt tccgaatata aagatgaagc tgtcgcttct atcgcgatat tggtaaagca
     6661 tataggtgag gaaaaaacag ccaattcccc agacaaggct aaatgggcca taaactacac
     6721 tgcttcggct tgtgatagtg cccatcttcc accagcaaaa gatagtttct gtaatatcgc
     6781 caagaaaaga gccaagaaag aacagccaga acagtttgta aaatccacat cctgctgcaa
     6841 atacaccagt catttcctgt gctttttctc gtctttgcag tttacttcgg atgatttcct
     6901 tgatttcgag accctcatgg cttttttcaa gatgttttaa cacccagcca gtcagaccat
     6961 ttcccatgta atctgcagct ttttgtaagt tatcagctac ttcttctaca aggactagtt
     7021 ttcctaatcg tgccaggcgg atatgtacac tcagaattcc tgaaatagtt ccgataaaat
     7081 caataacaat tactatatag acaataatca gaatgacttt tcctaatcca tatggaagta
     7141 tttcaataat tttacttaaa aatggattta caatccaaat acacaacagt gccgccgcac
     7201 cccatactac cgtataaggt aagttaacat agccaccaaa gttaaatctc cgtctggaat
     7261 aatctttcca tttctgatgg aaaatacgtt ctagggtcac tcctgtaaaa gatgtgataa
     7321 taaatgaaag aatcactcct cctgcaaata aaaatacagg ctggtctttt aattctggta
     7381 aaaataatgc aaaaccaacg gctccaaatc cgtaggatgg acaccacggg ccaaataaaa
     7441 atcctacgtc aataaacttt ttttctttta atgctgctcc agaagttcct attacccatc
     7501 ctgcaaagga atataacaga aaaaaccaga acacttcata ccaggtatag ctcaaaattt
     7561 ttctcctttt tttgaatttg tgatatacta tatcatattt ttgtgaaagg agaaagtatg
     7621 tgaatccacc aaatgctatt ttacatgaat tactaaatct tgcggaaatt atgctgacca
     7681 acggtgccga ggtcagccgt gtggaagaaa cgctgaaccg aatggggcat gcctacggtg
     7741 ccacccagat gaatgtattt gcaatcactt caagtatcgt tgtcactatg gtctttgaag
     7801 aaggcgaaga atatacacaa acccgaagaa tcactacccc tgtcggcaca gatttcttta
     7861 aattagaaca ggcaaatgca ctcagcaggc gctgttgttc ttctcctctt tcccttccag
     7921 atttgaaaga tgagataaat aaaatttcaa aaatcagtcc tgctccttat accatttacc
     7981 tgggaagcat gcttggtgca ggtggctttt ctgtcttttt tggaggaaca attttagacg
     8041 gagccattgc cgttatcttt gcctttctcc tttgcttttt acaaaggcat ttaaactcta
     8101 tatgcagcaa tactttaatc ctgcagtttt tctgctccct ttttgtcggc tccggcattt
     8161 gtgtagctgc acatttcttt ccggtaattc atgcagacaa agttatgatc ggtgacatta
     8221 tgctgctgat tcccggaatc cttatgacaa actctatccg tgacatttta atcggtgaca
     8281 cgatttcagg cgtgatgcgt cttgtagaat cgcttctttg ggcgggagca cttgcctgtg
     8341 gatttatgtg cgctatctgg tttgttggag gtgtgttatg atattacaat tctttgcagc
     8401 ctttattgga gctgccggct tcggattctt atttcatttg caatttaagc acattttccc
     8461 tgccgcatta ggtggtgtac tgacctgggt tatctatgtc atcgcaacta cctggggatt
     8521 tgatgttttc atttcttctc tatttgccag tgctttcgcc gcaatttact ccgaagtcat
     8581 cgcaaaaata agaaaagccc ctaccacctt atttttaatc atttccgttg tcgttctaat
     8641 ccccggcggc tctctctatt acacgatgag ttatgctgtt cagaaaaaat gggcagaagc
     8701 agcagcttac ggctcccaaa cattacagtg tgctttagga cttgccattg gaatgagcct
     8761 catctggata ttccacgata tggcaaggaa ggtttactat ttaattcatt aagagacaga
     8821 cgcccgggaa gagaaccgat accctatatt tgtgacttta gtcgctgcgg tttaaatgct
     8881 cgctttatgc gctcgcatct aaaccttgct ccgaggccac aaatataggg tatcggttct
     8941 cttcccgggc tgtctttggc tggattttgt ttgaattaaa tagtggttgt ggggatttgg
     9001 gggagagggt agaagttttc tgcttgctct taaaatattg tgaatagatg ttttgtattt
     9061 aaatagaaga ggtaatgaat tgatattgat aacaacagtc tgctttttat tctgaaatta
     9121 ttgaaatatt gctgagataa ccattaaaaa agctaaatca tccccctgtt cccagtcatt
     9181 cttgagtaag cagaagacat cagtttctgt ccccaaatcc cctccctctg tttaattcat
     9241 cttctccagc catagcacag aagccattgc ccccaataag gcatatttgt ggtctcggag
     9301 caagtgttgg atgcgagcga gtagagcgaa cattcaacac gccgcgacta aaatcacaaa
     9361 tatgccttat tcggggcaat ggcttcgtct gtagttcgct taatgaatta aatagtaacc
     9421 ccttgacatt ttgttctatt ttgtttatag ttagaatact tatacgactg acggaagtaa
     9481 gtggaatgaa ccacatgaag tataagactc ttatagccga ccgtctgggc aattcttgtc
     9541 tggatgctgg cttttttatt tctgataaga taatattcta tccaatatcc ctgataagaa
     9601 gtaactttaa atcgttatta agtcacgtgc taaagaagat gtttttccaa acatgctcta
     9661 aagagcgaaa aataaaatta tagttgtatg cttgtcatta ttgtacttat atcagtacat
     9721 ttgtacgatt tgataatatt ttatcaacgc tctaaaaccc tttattttaa aggctctaca
     9781 agcatttttg tgtatatgtt caaaaaaaag aacacataat atcaaaaaat tgtttgacga
     9841 ttgccaaaaa tcatgttaat aatgttgtta gatgattaaa acttaaataa gttaaaacta
     9901 atcatagtaa atcatctgaa caattttgtt gattttttag caaacatatt tcaaaacctt
     9961 gacttaagga tttttttaac aaacagggag gtcaattaaa atgttacaaa aagaacaatg
    10021 gcagggattt aatggacgaa tctggagaga agaaattaat ttaagagagt tcatccagga
    10081 taactacact ccatatgatg gagatgcttc tttcctcgaa ggccctaccg aggctactga
    10141 cacactgtgg ggcgaactgc agaagctgca gaaagcagag cgtgaaaagg gtggtgttct
    10201 tgatatggat actgatatcg tatcaagcct tacttcccat aaaccgggtt acatttctga
    10261 gtctttaaaa gagaaagaac agatcgtagg tcttcagaca gataaacctt taaaacgtgc
    10321 atttatgcca tttggtggta tccgtactgc tgaagaagct tgtacaactt atggttacac
    10381 accaaatcca gaattccaca agatttttac agattatcat aagacacata accaggcagt
    10441 atttgattct tatactcctg aaatgaagaa agctcgtcac aataagatca ttactggtct
    10501 tccagatact tacggacgtg gacgtatcgt tggtgactac cgtcgtgtag ctctttacgg
    10561 tattgacctg ttagttgctg acaagcaaaa agatttcgca aactgcggtg acggaacaat
    10621 gacagatgac gttatccgtt taagagaaga aatctccatg cagattaaag cattaaaaga
    10681 tatgaaagtt atggctgaaa gctatggcta tgatatttcc gaacctgctt ctaacgcaaa
    10741 ggaagctgtt caatggacgt atttcggata ccttgcagca atcaagacac agaacggtgc
    10801 tgctatgagt atcggacgta tcgctacttt ccttgacatt tatatcaaac gtgatatgga
    10861 taagggaatc cttacagaga aagaagcgca ggaattaatc gaccatatga ctatgaagtt
    10921 ccgtatggtt aagttcggac gtatcccagc ttacaaccag ctcttctccg gtgaccctgt
    10981 atgggcaaca cttgaagttg gcggacttgg acaggacggt cgttccatgg ttacaaaaac
    11041 tgactaccgt ttcctccaca cattagaaaa tatgggacca tccccagagc caaacctcac
    11101 agtactttac tctgagcgtc ttccaaaagc atttagagat tacgcagctc atatttctat
    11161 tacaacaagt tcaatccagt atgaaaatga tgatgtaatg cgtccagtat ggggcgatga
    11221 ttactccatc tgctgctgtg tttctgctac acagactggt aaggaaatgc agttcttcgg
    11281 agcccgtgca aaccttgcaa aatgtctcct ctacgcaatc aatggtggtg tagatgaaaa
    11341 gactggtcag caagttggtc cggaatacaa accaattact tccgaatatc ttgactatga
    11401 tgaagtaatg cacaaatatg atatcatgat ggactggtta gcaggtttat atgtaaatac
    11461 attaaatctc atccagtaca tgcatgacaa atattactat gaatatgctt tgatggcctt
    11521 aatcgataca aatgtacgtc gtacattcgc tacaggtatc gcaggattct cacatgtagt
    11581 agattcctta agtgcgatta aatatgccaa agtaaaaaca gtccgcaatg aagaaggact
    11641 tgttgttgat tatgagacaa ctggcgactt ccctaaatac ggaaatgatg atgaccgcgc
    11701 tgatgatatc gctgtatggt tacttcagac atttatgaag aagcttgaaa aattccatac
    11761 ttaccgtgat tctgaaccta caacttccat ccttactatc acatcaaacg tagtatatgg
    11821 taaggcaact ggttcccttc cagacggaag aaaggccgga gaacctcttt ccccaggagc
    11881 aaacccaagt tatggtgctg agcagaacgg acttttagct tccttaaact ctgtagcaaa
    11941 acttccttac gaatgggcat tagatggtat ttccaataca cagacaatca accctgatgc
    12001 actcggtcat tccgaagaag aacgtatcaa taacttagta aatgttatgg acggctactt
    12061 cgcacagggt gctcaccacc taaacgtaaa tgtatttggt gttgagaaac tgattgatgc
    12121 tatggaacat ccggaaaaag aagaatacgc aaactttacg atccgtgttt caggttatgc
    12181 agttaaattc atctctctga caaaagaaca gcagttagat gtaattgcca gaacatgcca
    12241 tgacagaatg taataaaaat gcgatggctc ttgttcattc tacggagagt tttggttcgg
    12301 tggatgggcc gggagttcgt tttattgttt ttttacaggg ttgtcctttg cgatgtcagt
    12361 tctgtcacaa tccagataca tggaagatga cagaggaaaa tggtgcggtg tggagaagtg
    12421 cggatgagct gttaaatcag gcactccgtt atcgtactta ctggaaaaat agcggcggta
    12481 ttaccgtaag tggtggtgag cctcttttac agattgattt tatgctagag ttttttaaaa
    12541 aggcaaaaga aaaaggaatc cacactgtta ttgatactgc tggaggacct tttacaagag
    12601 aggaaccttt cttttctaaa tttcaggaat tgatgaaata tacagacctg ttattagtgg
    12661 atatcaaaca tattgatact gaatgtcaca agactttaac tggtcgaagc aacgaaaata
    12721 ttctcgacat gattcgctat ctttctgata tcaaaaaacc aatttggatt cgtcatgtcc
    12781 ttgttccgga acgaagcgat aaagatgaat atctgactag attagctgat ttcattcact
    12841 ctcttgataa tgtggaaaag gtggaaatcc tgccttatca tacgatggga atttataaat
    12901 ggaaagaact tggattagag tatccactgg agggaattga gccaccaaca aaagaacgag
    12961 tggagaacgc taagaaaatt cttgctattt gatttgccga caaacagaat cctaaaaacc
    13021 cccatatttg tgactttgaa gatagattgc gttgaatact tattcatctt caatctatcc
    13081 ttgaagtcac aatatggggg gtctctggta tgctcccttt taggtagaca gttaaaaaaa
    13141 taaaactgtt tatctgaaag ggggcatttt ttatggataa gatttctcca gaagaaaaaa
    13201 tacaatggat gaaaaaaatt
//
