LOCUS       gnlProkkaDEOFBCOA_17   15915 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DEOFBCOA_17.
ACCESSION   gnlProkkaDEOFBCOA_17
VERSION     gnlProkkaDEOFBCOA_17
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 00:41:09
            Original ID  :: gnl|Prokka|DEOFBCOA_17
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 29527
            Orig. end    :: 45442
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15915
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10351]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10351
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15915
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15915
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2217..3269
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_25"
                     /sec_met_domain="PF04055 (E-value: 6.7e-17, bitscore: 53.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNDMQKRPLLGLTLSELQNVVKNLGMPGFSAKQIASWLYDKKVT
                     SIDEMSNLSLKHRELLKEIYEVGAEAPVDAMRSVDGTVKYLYRAGEGHFVEAVYIPDED
                     RATLCVSSQVGCKMNCKFCMTGKQGFTANLTSNQIINQINSLPERDKLTNVVMMGMGEP
                     LDNLDEVLKALEIMTASYGYAWSPKRVTLSSVGLKKGLQRFIEESDCHLAISLHSPIPL
                     QRRELMPAEKAFSITEIVELLRNYDFSKQRRLSFEYIVFKGVNDSLPYAKELLKLLRGL
                     DCRINLIRFHAIPGVNLEGADMETMTAFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTA
                     KQEENKEELI"
     CDS             3367..4395
                     /locus_tag="ctg17_26"
                     /transl_table=11
                     /translation="MVLVLTLFSACGGGKKGVFTPTSSGRAYEVLVVVEPGLWERPAGR
                     ALFDVLDSDVPGLPQSERSFRIMYTAPSNYDATLKLIRNIIIVDVNKDLYTQPKFKYAR
                     NVYAAPQSILTIQAPDEASFEKFVEENRQVIIDFFTHAEMNRQISVLKDKHSDYIATKV
                     KSQFDCDVWVPGELTSTKEGENFFWAGTNAATGDQNFVIYSYPYTDKDTFTKEYFVHKR
                     DSVMKVNIPGAREGMYMSTDSLMTDVRPIGVQGDYALEARGLWRIKGDFMGGPFVSHVR
                     LDKANQRIIVSEIFIYSPDKMKRNLVRQMEASLYTLKLPGSKQEGTEIPVGVTSKDTTN
                     NK"
     CDS             4401..5498
                     /locus_tag="ctg17_27"
                     /transl_table=11
                     /translation="MEDNKIRVGITQGDINGVGYEVILKTFADPVMLELCTPIIYGSPK
                     VAAYHRKSLDLPTNFSIVNSASEAVPNRLSVVNCTDDEVKVEFSKPDVEAGKAALGALE
                     KAIEEYKEGMIDVIVTAPINKHTIQSEEFAFPGHTEYIEQKLGDGEKALMILMKDDFRV
                     ALVTGHIPVKEIAGSITKELIQEKLKIFNRSLKQDFAISAPRIAVLSLNPHAGDGGLLG
                     TEEQEIIIPAINEMAAKGMLCYGPYPADGFMGSDNFTHFDGILAMYHDQGLAPFKALAM
                     DEGVNYTAGLPVIRTSPAHGTAYDIAGKGIASEDSFRQAIYVAIDVFRNRQREKEAHAN
                     PLRKQYYEKRDDSDKLKLDSVEEDL"
     CDS             5500..6750
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 379.9; E-value:
                     3.1e-115)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg17_28"
                     /transl_table=11
                     /translation="MTKAEIQQVKLRFGIIGNNEALMRAIDIAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EANGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVEKTDVRIVAATNVNLTQAI
                     ADGRFREDLYYRLNTVPIQVPPLRERGEDVVLLFRKFASDFAEKYRMPAIQLTEDGKQV
                     LLGYSWPGNVRQLKNITEQISIIETNREINASILKGYLPEQNNMQRLPALFGVKEDKSF
                     GSEREILYQVLFDMRQDVTDLKKLVHEIMAERGTVANPAVATSAYYTPATPAVVPPVTS
                     SVPTIIHPSVKPVTPVDDDFQDTEEYVEESLSLDEVEKEMIRKALEKHHGKRKSAAQDL
                     NISERTLYRKIKEYGLD"
     CDS             6770..7261
                     /locus_tag="ctg17_29"
                     /transl_table=11
                     /translation="MLVSLLFLVNSCSMKLGLAPISSIDYTKVKTISIADFQNRAEYVY
                     APLATEFNQKMKDMFIQQTRLQLVNSGGDLEIDGEITGYNQYNESVDASGYSSKVKVTL
                     TVNVRYTNNTNHEEDFEQQFSAFQTYDSSKLLTEVQDQLITLMVKDIAEQIFNATVANW
                     "
     CDS             7344..8039
                     /locus_tag="ctg17_30"
                     /transl_table=11
                     /translation="MVARYPYFQSLRLLYLKNLYLLHDINFGAELRKAVLYVADRRVLF
                     YFIEGDRYTLKSRKVSSLFSGDLEKEPSVDRTLSLIDAFLATVPEEHSQHTELDYAVDY
                     TAYLMQEEPGVDAEDESEVPKLRGHELIDDFIQKSESSDASDTRREFLVEKEEETEEEE
                     EPSVSPVTEELDDSCFTETLAKIYIKQHRYDKALEIIKKLSLNYPKKNAYFADQIRFLE
                     KLIINAKSK"
     CDS             8044..8433
                     /locus_tag="ctg17_31"
                     /transl_table=11
                     /translation="MYLLLVILMLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEA
                     PQSEAPAATTPAEAPAPAAEAPAAE"
     CDS             8587..9978
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 100.6; E-value: 1.2e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg17_32"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMAAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGADATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFIFAVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLIVALLLKKADKKYGYKLEE
                     PNIQK"
     CDS             10001..10351
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_33"
                     /sec_met_domain="PqqD_RRE (E-value: 3.4e-10, bitscore:
                     31.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.1e-17, bitscore: 53.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIPEGKVSLLDAVPVRCGHITTEWEGECAVLAYPRFKYEWMRRF
                     LLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIISLLARHFGEEENYIPRVTAYVMQL
                     RKDGFIQLTIRN"
     CDS             complement(10359..11417)
                     /locus_tag="ctg17_34"
                     /transl_table=11
                     /translation="MYIMKKNILMLSALFLSITAMAQTDVTTGVMRGKDYGVTYMLPKT
                     EIEIVLQATKHTYTPGEFCRYADRYLRLNNVSAEPEEFWTLDKIETRIAGVPDKDNVYF
                     VKMKDKTVAPLMELTEDGIVRSINIPFSGKPAAKTPEAKATESSIDPRSFLTEEILMSN
                     SSAKMAELVAKEIYSIRESKNALLRGEADNMPKDGAQLKLMLDNLNQQETAMTEMFSGK
                     IKKEPKTFTIRLTPKEMKDEVAFRFSRKLGVVANNDLAGEPYYISVTDLKSPDVSATEE
                     GKKKVDGVAYNLPGKAQVTLVYNNKKLFDDQLPITQFGTVEYLAPVLFNKNSTIKVLFD
                     TATGGLIKVDRE"
     CDS             11542..12072
                     /locus_tag="ctg17_35"
                     /transl_table=11
                     /translation="MSIFQESGNFVSFVYLNDIAVAAGGKQVFTVGRDVEVAGMDAGGL
                     ITYLCQGPIFGIHGKDGDAVFFQTVAGVEVFPIRTEVDVCTSTGGYGVGCDSLYLFQAA
                     VVVTEGNDLTGQFGDEIGKLPVRAECQMARAGICLNANGFQRSMRNRVVGVHHKAQDAV
                     GTEVGGEDILSVR"
     CDS             complement(12708..13043)
                     /locus_tag="ctg17_36"
                     /transl_table=11
                     /translation="MSASTNPEDAENVLDEKINTAWQGNKGDYITFALKNGAKVDKVAI
                     AFTRDNNLPATFEIQLSGGGGQFLTVYSGTVSEYGKLISYPFKGTTASDLRIVLNDDRV
                     SIAEVKF"
     CDS             13059..13496
                     /locus_tag="ctg17_37"
                     /transl_table=11
                     /translation="MGFNGFGTGLVVFYGQRSVQADVFGRGAGHEHEVAGFHHPFHVSV
                     QKLQVLAVDGEGQLLGFARFEVDALEACKILFVGGDAAQYVADIELHYFISGTFAGVGH
                     LQADGGRLVRGDDSGGDVEVGVLEGGVAQAVTEGVECSVDA"
     CDS             13572..14153
                     /locus_tag="ctg17_38"
                     /transl_table=11
                     /translation="MPYGLGEGHRQLSTGVVVAEEDVGQGCSAFGAGIPGFEDSGDELV
                     CPVDGERASVDEYQYDGLARGLYGLKQLQLPTGQVEAGARFVFAAGALSAAQYYDGNIS
                     LTGIFYGFVYLGLFVVGQRIVYDFTFGPVGVHQVAAFGVEHLCLAFCLFLNAFQHSGHF
                     YGKWAVMGQRVAFFIGIGTTDGNLLGGVDV"
     CDS             14442..15518
                     /locus_tag="ctg17_39"
                     /transl_table=11
                     /translation="MADGFFHVFGGAVLGVEVFYGVTVGYDVATESHFATQAGGEPVVA
                     ALHGDAVVIVVRTHYAQHAGFPDDAFEGVDVYVLHFARRHLRVHACHAFAGAFVVTVSG
                     KVLAGGGHLVVVLQAAHHFDAQFGYEVGGFAVNFFVASPALVASYVEDGGVDVGVAQHA
                     GFASGDESYLANQFTVPGMSQSQLGGEVGGAVAFHAAYAFVGKVYGDAETGIFHKEPLH
                     LVQCPGVARGGPDVGIVRGRQPPLLEAVQVFVDGADTVFPEQLFPFGGGEVVFQYAFVA
                     VEGDHLAGLFVQRHLLQQVFDACFERGGGVFVHVFHSVFVEVYPTFAVHFTFHRLVGCR
                     CFGRLLCAEQCASSKQQG"
ORIGIN
        1 tgtttgcttt catcgcaggt gacgcgtgga aagtgcttca gccacaccag tcacaagacg
       61 taggtgaagt gaacggggaa tcaatttccg ctcaggattt tcaagcattg gtagaagaat
      121 atacagaagt catcaagttc tccagtggca acagtgcatt gagcgatgag cagacaaacc
      181 aaatcaaaga tgaagtatgg agaacatacg tcaataataa gctgattgaa aaggaagcaa
      241 agaaactcgg tctggttgta tcgaaggctg agattcaggc tatcattaat gccggtgtgc
      301 atccgatgct gcaacagact ccgttccgta atcctcagac cggtgcgttt gataaggata
      361 tgttgaagaa gttcttggtg gactattcaa aaatgaataa ggcacagatg ccttcacaat
      421 atgcagaata ctatgaatcc atgtacaagt tctggtcttt cctcgaaaag tcccttatcc
      481 aggcacgtct tcaggagaag tatcaagctt tgattacaaa atcccttttc tccaacccgg
      541 tagaagctca ggacgctttt gatgcaagag tagagcagtc agacctgctg cttgctgcag
      601 ttccctattc ttctatcgtt gactctacca tcgttatcaa ggattctgat ttgaaggctg
      661 catacgacaa gaagaaagaa cagttcaagc aatatgtgga aactcgcaat atcaagttca
      721 ttgatgtgca agttactgca agtgcagaag acagagctgc tctccagaag gaaatggaag
      781 aatacactga acaacttact gccaatcctt ctgactatac tacctttatc cgttctaccg
      841 gttccgaagc tccttataca gacttgttct acactactaa gtctctgcct gctgatgtga
      901 cagcccgttt ggactctgtt gcggtgggtg gtgtattcgg accttattat aacgtatcgg
      961 acaatactct taactctttc aagaaattgg ctactgctgc catgccggac tctatcgagt
     1021 tccgtcagat tcaggtagtt gccgaagatg ctgaaaagac gaagacttta gccgacagca
     1081 tctacaatgc tattaagggt ggtgccagct ttgctgaaat tgcgaagaag tacggtcaga
     1141 ccggtgagcc tacctggatc tcttcagcta actacgaagg cgcacagatt gacggtgaca
     1201 acttgaaata tattactgct gtcactactt tgggacagaa cgaactgacc aatctggcgt
     1261 tgggacaagc aaatgtcatt ttgcaggtaa ccaacaagaa ggctgtcaag gataaatata
     1321 aggtagccgt tatcaagcgt ccggtagaat tcagtaagga aacttacagc aaggcataca
     1381 atgaattcag ccagtttatc gctgcaaaca atactttaga gaaaatgatt gccaatgcgg
     1441 aagatgccgg ttataagttg ttggatagag ccgacttgta cagctctgaa catggtatcg
     1501 gtggtatcag aggtaccaaa gatgctttga aatgggcgtt tgaggcaaag gccggtgaag
     1561 tttccggttt gtacgaatgt ggcgagagcg accgtatgct ggtagtaggt gttgcaagta
     1621 ttgttcctga aggttatcgc ccactggctt tggtaaagga ccagttgaga gctgaaattc
     1681 tccgtgataa gaaagcagag aagattatgg ctgatatgaa ggctgccaat gcaacttcgt
     1741 tcgagcagta caagaatatg gcaaatgctg ttagtgattc tgtaaagcac gttactttct
     1801 ctgctcctgc ctatatcccg gcattgcgta gcagcgaacc tctggtaggc gcatacgctt
     1861 ctattgccga agtgaacaag ctgagtgctc ctatcaaggg taacggtggt gtattcgttc
     1921 tgcaacctta tgcaaaagag aagctgaacg aaacattcaa caaggaaact gaagaggcta
     1981 acttggctaa catgcacgca cgcatggcaa gccagttcat cagtgacttg tatctgaaag
     2041 ccaacgtaaa agaccaacgt tatttattct tctaagaata gaaaacccat attgaaaagc
     2101 cgttcggtac tcccgggcgg ctttttcatt ctctgtacat ttcattttct atactctccg
     2161 ttgtctttgt gcaactttat tcctaccttt gcattcttga aagagttttg tttttaatga
     2221 aaaacgatat gcagaaacga cctctattgg gcttgacgct ctctgaattg cagaatgtgg
     2281 tgaagaatct gggaatgccc ggtttctctg ccaagcagat agcttcctgg ctgtatgaca
     2341 agaaggtgac ttctatagac gaaatgagca atctttcgtt gaagcatcgg gaattgctga
     2401 aagaaatcta tgaggtaggt gccgaagcgc cggtagatgc catgcgctct gtagacggta
     2461 cggtgaaata cttgtaccgg gcaggcgagg ggcatttcgt ggaagctgtc tatatacccg
     2521 acgaagaccg ggctacgctt tgtgtctcct ctcaggtggg ctgtaagatg aattgcaagt
     2581 tctgtatgac cggcaaacaa ggttttactg ccaatctgac atccaaccag attattaatc
     2641 aaatcaattc gttgcccgaa agggacaagc ttaccaatgt ggtaatgatg ggcatgggtg
     2701 aaccacttga taatctggac gaggtattga aagcgctgga aataatgacc gcctcttatg
     2761 ggtatgcgtg gagtcccaag cgtgttacac tttcttctgt gggattgaag aagggcttgc
     2821 agcgttttat tgaggaatcg gactgccatc tggctatcag ccttcattcg ccgatacctt
     2881 tgcaacgccg cgaactgatg ccggcagaga aggcgttctc catcacggag attgtggaat
     2941 tgttaagaaa ctatgatttt agcaaacagc gcagactatc ttttgaatat attgttttca
     3001 aaggagtgaa tgactcgtta ccgtatgcaa aggaacttct gaagctgcta cgcgggctgg
     3061 actgccggat taacctgatt cgttttcatg ccatacctgg agtgaatctt gaaggggctg
     3121 atatggaaac catgactgcg ttccgtgatt atctgacttc gcacggtctg tttaccacta
     3181 tacggtcatc gcgtggagag gatatatttg ccgcttgtgg catgttgtcc actgccaagc
     3241 aggaggagaa taaagaagaa ttaatataaa ttattaactt aggtagggag gatattacgc
     3301 attcttcgta gctttgtgaa aaactaaaat gatagagata tgagaaagca cttgttttat
     3361 ttaagtatgg ttctcgtact gacacttttt tccgcttgcg gtggtggtaa aaagggtgtg
     3421 tttactccga cctccagtgg tcgtgcgtat gaagttctgg tagtggtgga gcccggcttg
     3481 tgggaacgtc ctgccggtag ggcgcttttc gatgtgcttg attctgatgt tccggggctt
     3541 ccccagtcag aacgttcatt ccgaatcatg tatactgccc cttccaatta tgatgccact
     3601 ttaaaactga ttcgcaatat cattattgtc gatgtgaaca aggacctcta tacccagcct
     3661 aaattcaagt atgcaaggaa tgtatatgct gctcctcagt ctattctcac tattcaggca
     3721 ccggacgagg cttcgttcga gaaatttgtg gaggagaata ggcaggtaat catcgatttc
     3781 tttacccatg cggaaatgaa tcgtcagatt tcagtattga aggacaagca tagcgactat
     3841 atagcaacga aggtgaaaag ccagttcgat tgcgatgtat gggtgccggg cgaactgaca
     3901 tctaccaagg agggtgagaa cttcttctgg gcaggtacga atgcagctac cggcgaccag
     3961 aactttgtaa tctactctta tccttatacg gataaggata cgtttactaa agaatatttt
     4021 gttcataaac gcgattccgt gatgaaggtt aatatccctg gtgcccgtga aggcatgtat
     4081 atgtcgacgg attctctgat gaccgatgta cgccccatcg gtgtgcaggg agactatgca
     4141 ctggaggccc gcggcttgtg gcgcataaag ggtgacttca tgggcggtcc gttcgtatcg
     4201 catgtacgtt tggacaaggc caatcagcgt attatcgtat ctgaaatatt tatttattct
     4261 cctgataaaa tgaaacgtaa tctggtacgt cagatggagg cttcgctcta taccttgaaa
     4321 ctgcccggca gcaagcagga aggtacggaa attccggtag gcgtaacctc aaaagatact
     4381 actaataata agtaataaaa atggaagaca acaaaataag agtcggcatt acacaaggcg
     4441 acattaatgg tgtagggtat gaagtgattt taaagacgtt tgcagacccg gtgatgctgg
     4501 aattgtgcac gccgattatc tacggttcgc ctaaagtggc agcttatcat cgtaaatcat
     4561 tggacttgcc taccaacttc agtatcgtca actccgcctc cgaagcggtt cccaatcgct
     4621 tgagtgtagt gaactgtacg gatgatgaag taaaggttga gttctctaaa cctgacgttg
     4681 aagctggtaa agctgcactt ggtgcactgg aaaaagccat tgaggaatat aaggagggaa
     4741 tgatagacgt gattgtcaca gctcccatca acaagcatac catccagtcg gaggagtttg
     4801 ccttccccgg acatacggag tatatagagc aaaaattggg agatggcgag aaggccctta
     4861 tgattctgat gaaagatgac ttccgggtag cattggtgac cggacatatt cccgttaaag
     4921 agatagccgg aagcatcacc aaagaactga tacaagaaaa actgaagata ttcaaccgct
     4981 ccttgaagca ggattttgct atcagcgcac cgcgtattgc agtgctttcg ctgaatccgc
     5041 atgcaggaga cggcggattg ctgggaactg aagagcagga gattatcatt ccggccatca
     5101 acgaaatggc tgctaagggt atgctttgct atggtcctta tccggcagac gggtttatgg
     5161 gctcagataa ctttacccat tttgatggta tcctggccat gtatcacgac caggggctgg
     5221 caccgttcaa ggcattggct atggacgagg gcgtgaacta tactgccggc ttgccggtga
     5281 tacgcacttc gcctgctcat ggcacggcct acgatattgc cgggaaagga atcgcctctg
     5341 aagattcatt ccggcaggct atctatgtgg caatagatgt gttccgtaac cgccagcgtg
     5401 agaaagaggc acatgcaaat ccgctgcgca agcaatatta cgagaaacgt gacgatagcg
     5461 acaaactgaa actcgatagt gtagaagaag atttgtagaa tgacaaaagc ggaaatacaa
     5521 caagtaaaat tacgtttcgg cattatcggc aacaatgaag cgctgatgcg tgccattgat
     5581 atcgctatcc aggtagcgcc caccgacttg tctgtactga ttaccggaga gagtggtgtg
     5641 ggaaaggaga gctttccgca gataatacac cagtacagcc ggcgcaagca tggacagtac
     5701 attgccgtga actgtggagc cattcccgaa gggacgattg actcggaact gttcggtcat
     5761 gagaagggcg catttaccgg ggctatcggc gaacggaagg ggtatttcgg tgaggccaac
     5821 ggcggaacaa tcttccttga tgaagtcggc gaattgcctt tgcctaccca ggcacgcttg
     5881 ttgcgtgtgc tcgagagcgg tgaattcatc aaagtaggtt cttctaaggt ggaaaagacc
     5941 gatgtgcgta ttgttgccgc taccaatgta aacttgacac aagccattgc tgacggacgt
     6001 tttcgtgaag acttgtatta ccgtttgaac acagttccta ttcaggtccc tccattgcgc
     6061 gaacgcggtg aagacgtggt gctgctgttc cgaaagtttg cttcggactt tgcagaaaag
     6121 taccgtatgc ctgccattca gctgacggaa gacggcaagc aagtgttgct gggctactca
     6181 tggccgggta atgtgcgcca gttgaagaat atcaccgagc agatatccat cattgagacc
     6241 aatcgtgaaa tcaatgcatc catactgaag ggctatctgc ctgagcagaa caatatgcag
     6301 cgcctgcctg ccttgtttgg agtgaaggag gacaagagct ttgggagtga acgggaaatt
     6361 ctctaccagg ttctgtttga tatgcgccag gatgtaacgg acttgaaaaa gttggtgcat
     6421 gagattatgg ctgaaagggg aacggtagcc aatccggcgg ttgccacatc ggcctactat
     6481 acgccggcta ctccggcggt ggtacctccg gtaacatcca gtgtccccac cattatacat
     6541 ccttcggtaa agccggttac tccggtggac gatgatttcc aggatacgga agaatatgtg
     6601 gaggagtcac tctccctgga tgaagtggag aaagaaatga tacgtaaggc gcttgaaaaa
     6661 catcacggca agcgtaagag tgcggctcag gatttgaata tctctgagcg tacgttatac
     6721 agaaagataa aagaatatgg attggattaa aaaagcggca tttgcttcct tgttggtaag
     6781 cttgttattt ctggtgaatt catgtagtat gaagttggga cttgctccga taagctctat
     6841 cgactataca aaggtaaaaa cgatttccat tgccgatttc cagaaccggg cagagtatgt
     6901 atatgcaccg ctggcaacag aatttaacca gaaaatgaag gatatgttca ttcagcagac
     6961 tcgcctgcaa ctggtgaatt ccggaggaga cctggaaata gacggagaaa taaccggcta
     7021 caatcaatat aatgaatcgg tggatgccag cggctactct tcgaaggtga aggtgacgct
     7081 gactgtcaac gtgcgctaca ccaataacac gaaccatgag gaggactttg aacagcagtt
     7141 ctcggctttc cagacctatg attcctcaaa attgctgacc gaagtgcagg accagctgat
     7201 aaccttgatg gtgaaagaca ttgccgaaca gattttcaat gcaactgtag ctaactggta
     7261 aactcatgac gcctacccat ttgcaacaat ggattcagca tcccgagacg ctgaataggg
     7321 atactttgta cgagcttcgc acattggtgg cacgctatcc ttatttccag tcgctccgtt
     7381 tgctctatct gaaaaacctc tatctgctgc acgacatcaa ctttggcgcg gagttgcgca
     7441 aggctgtgtt gtatgtggca gaccgtcgtg tgctgtttta ctttatagag ggtgaccgct
     7501 atactttgaa atcccggaag gtctcgtcgc tgttttccgg cgatttggag aaagagccga
     7561 gtgtggaccg taccctttcc ttgattgacg catttctggc tactgttccc gaagagcatt
     7621 cacagcatac ggagctggat tatgcggtgg attatacggc ctatttaatg caggaagaac
     7681 ccggtgtgga tgcagaagat gagtcggaag tgcctaaact gcgcgggcat gaattgatag
     7741 atgactttat ccaaaagagt gagtcttcgg atgcctcgga tacgagaagg gagtttcttg
     7801 tagagaagga ggaagagact gaagaagagg aagaaccctc agtatcgccg gtaacggaag
     7861 agttggacga tagctgtttt acggaaactt tagccaaaat ctatataaaa cagcaccgat
     7921 atgacaaggc gcttgaaatt attaaaaaat taagtttgaa ttatccaaaa aaaaatgctt
     7981 actttgcaga ccaaatcaga tttttggaga aattgattat taacgctaaa tcaaaataac
     8041 aaaatgtatt tattattagt tatcttaatg ctgattgcat ctgtgctgat gtgcttcatt
     8101 gtattgattc aaaattctaa aggaggtggt ctggcatcag gcttttcatc atccaaccaa
     8161 attatgggtg tgcgcaagac tacggacttt ttggaaaaag caacctggac tctggcagct
     8221 gtcatggtag tcttcagtat tgtttctgct tacactattc cttcttccac aggcaagggc
     8281 ggtgatgtga ttctggaaca ggcgcaacaa gaagaaaaaa ctaatcctta taacatgccc
     8341 gtaggtacag aagctccgca atcggaggcc cctgcagcta caactccggc tgaagctcct
     8401 gctcctgcag cagaagcccc tgcagcagaa taagataagg atattgcgga tgactcccgc
     8461 ttggaaaaat aagagaaagg ttgatactga aaaggtgtca gccttttttc gttttgatga
     8521 agtatttatt tacctttgtc agcaatttat gcaatctgat taataaattg aaatccaaat
     8581 agtacaatga cagaacaact caaacttaaa ttgaatgatt ccaaggctac ccgttggggg
     8641 gcattggtga ttgttgcctt cacgatgatg gcagcttatt atgtaaacga cgtggtagca
     8701 ccgttgaaga caatgttgga aacggacttg gcttggtcga gtaccgattt cggattcttt
     8761 accggtggtt atagttttct gaatgttttt ttcctgatgt tgatttgggg aggattaatc
     8821 ctcgaccgct ttggtatccg tttcaccgga aagctggcaa ctatcctgat ggtaggtggt
     8881 acagcacttg aatactatgc aatgacggga cttgccggtg ccgacgcgac tttattcgga
     8941 atcaatgaaa tatttggcta taaaacgggt gtgtttgttg cttttgccgg ttattccatt
     9001 tttggagtag gagcggaggt cgccggtatt acagtttcca aaatcatagc caagtggttt
     9061 aaggggaaag agcttgccac ggctatgggg gtacaagtcg ctttagcacg tatcggttcg
     9121 caagccggtt atgccgtagc cattcctttg gcccgcgctt tcggtatttc cacaccggtg
     9181 ttgttgggtt tggttctgtt gttgggcggt atgattgctt tcttcatctt tgcagtgatg
     9241 gacaagaagc tggacaaaca gatggaagct gctgccattg ctgccggtac ggaagatgag
     9301 gaagagaagt tctcttttaa ggatgtgaag aatattctgg tcaatcccgg tttctggctg
     9361 atagcattgc tgtgtgtatt gttctactct tgtgtattcc cattccagaa gtttgcttcc
     9421 gagttgatga ttatcaaata cggtatcaat gagaatgtgg ccggtacatt tgccggactt
     9481 ccggcattgg gagcgctgat tctgactccg gtctttggtg gtttcattga caagcggggc
     9541 aagtccgcat ctatcatgct gctgggctcg gccatgctga tatgtgtgca tttcatttat
     9601 gctattcccg atataaacta ttggctggta gctattgtgc tgatgataat tttgggtatc
     9661 gctttctcgc tggtaccttc tgccatgtgg ccggctgtgg ccaagatatt cccggtaagc
     9721 cagttgggta cggcatacgc attgattttc tttatccaga atatcggtct ttggggtatt
     9781 cctacattga tagggtgggt gcttgatgcc tattgtatat ccggcaagaa accagatgga
     9841 acgaatatgt atgactatac ggtgcctatg tgcattttta ccggtattgc ctgcttgtcc
     9901 cttatagtgg ctctactgct gaagaaggca gacaagaagt atggttataa gctggaagag
     9961 cctaatattc agaaataata ggaaaagcgg ataccgtatg atggaaatac ccgaaggaaa
    10021 agtaagtctg ttggacgctg ttccggtccg ctgtggacat ataacaaccg aatgggaagg
    10081 tgagtgcgcc gtactcgcct acccacggtt taaatacgaa tggatgcgtc gttttttatt
    10141 gccgaagggg atgtctcctg acatccatgt gaggctggaa gaacacggta cagctgtctg
    10201 gaatctgata gatggacatc gtaccgtgcg cgaaatcatc tctctacttg ccaggcactt
    10261 tggggaggaa gagaattata ttccccgggt caccgcctac gtaatgcagt tgcgtaagga
    10321 tggatttatc cagttgacaa tccggaatta gaattccttt attccctatc tacttttatc
    10381 aatcctcccg ttgccgtatc aaacagcact ttgatggtag aattcttgtt gaacagtacc
    10441 ggtgcgaggt attctacggt gccgaattgg gtaatgggaa gttggtcgtc aaacaatttc
    10501 ttattgttat acaccaatgt cacttgtgcc ttgcccggaa ggttataggc tacaccgtcc
    10561 actttctttt tgccttcctc ggtggcagat acatcgggac ttttgaggtc ggtgacgctg
    10621 atataatacg gttcaccggc aaggtcatta ttggccacca ctcccagctt tcgggaaaaa
    10681 cggaaagcca cttcatcttt catctcttta ggcgtcagcc ggatggtgaa tgtcttgggt
    10741 tctttcttta ttttgcccga gaacatttcc gtcatagccg tttcctgctg gttcagattg
    10801 tcaagcatca gcttgagttg ggcgccgtcc ttgggcatat tgtctgcttc gccgcgcagg
    10861 agggcattct tgctttcgcg gatgctgtat atttccttag ccaccagctc ggccatcttg
    10921 gcactggagt tggacatcag tatttcttcc gtcagaaaac tgcgtgggtc aatgctgctt
    10981 tcggtggctt tggcttcggg cgtcttggca gcaggcttac cgctgaacgg aatgttgatg
    11041 gagcggacaa ttccgtcttc ggtaagctcc ataaggggtg ctacggtctt gtctttcatc
    11101 ttcacgaaat agacgttgtc cttatccggt acaccggcta tgcgggtttc tatcttatcc
    11161 agtgtccaga actcctcggg ttcggcagac acgttgttga gacgcagata gcggtcggca
    11221 tatctgcaaa attctccggg agtgtaggta tgcttggtgg cttgcaatac gatttctatt
    11281 tctgttttgg gcaacatata agtcactccg tagtctttgc cacgcatcac accggtggtt
    11341 acgtctgttt gcgccatggc agtgatagat aagaacagag ctgagagcat caatatattc
    11401 ttcttcataa tgtacattcg tttagactga tttagctaag ggacaaagtt aatgaagtta
    11461 tctttgctaa atattgcttt ataaattatt aacagagctg acgaactgta cgcaaaccgg
    11521 catgtcgact acaatgtcct gatgagtatc ttccaagagt ccggtaactt cgtttcgttt
    11581 gtatacctga atgacattgc tgtcgcggca ggcggcaagc aagtatttac cgttgggcgt
    11641 gatgttgaag ttgcggggat ggatgccggt gggctgataa cctacctttg ccaaggtccc
    11701 attttcggga ttcacggcaa agatggcgat gccgtcttct ttcagacggt tgctggcgta
    11761 gaggtatttc ccatccggac tgaggtggat gtctgcactt ccacgggcgg ctacggtgtc
    11821 ggctgtgata gtctgtatct gttccaggca gccgtcgtcg taactgaagg caatgacctt
    11881 accggacagt tcggtgatga gataggcaaa cttcccgtta gggctgaatg tcagatggcg
    11941 cgggccggaa tctgcctcaa tgccaacggc ttccagagaa gcatgaggaa tagggttgtc
    12001 ggggtgcatc acaaagcgca ggatgcggtc ggcactgaag tcggtggcga agatatactt
    12061 tccgtccggt gaaaagaccg tgcaatggat gtggggagtg gcttgccgta tggcgtcggg
    12121 accggtggca gagccttgaa agagcgtgtc tgcaggagcc aaagtgccgt ctttctgtaa
    12181 aggaaagacg gacatggttc caccgctgta gttggcagtc aacacttccc ggccattggt
    12241 ggccacgtag caggggtcgg cgccgaaggt gggaacggtg ttcagcaggc gcagttctcc
    12301 cgtttcccgg tcgaaggcaa gggagctgag ggctgctgtg ctgtcgttca tttcactgac
    12361 ggcatagaca aattcgccat cttccgaggg gacgaggtag gagggattgg gcaatgccgc
    12421 tgaactgagc ggaacggctg ttcccgtctc ctgattaaag cggaaggtat agataccctt
    12481 gcttgagcca ttagtgtaag tacctattag catggcgagt tcgtcctggt caccgttagt
    12541 gccctttgga gaagagccac atgctgtcaa acctaatccg agcatacaga aaagaagtgt
    12601 tttcattaat ttaatgtgtt aatgtgccaa tatgctaatg tgctaattgg ctgcgctgta
    12661 tatgctgcat ggtcattggt acattagcat attggcacat tagcacatta aaatttaact
    12721 tcggcaatac tgacgcggtc atcgttcagc acgatgcgga ggtcgctggc ggtagtgcct
    12781 ttgaacggat aggaaatcag tttgccgtat tcgctgacgg tgcccgaata tacggtgagg
    12841 aactgtccgc caccgcccga gagctggatt tcgaaggttg ccggcaggtt gttgtcacgt
    12901 gtaaaggcaa tggcaacttt atctaccttg gctccgttct ttaaggcaaa ggtaatataa
    12961 tctcccttat ttccttgcca tgcggtattg attttttcgt cgagcacgtt ttcggcatcc
    13021 tctgggttgg tgctggcact cacacgcttt gctggttttt gggcttcaat ggctttggca
    13081 cgggtctggt agtcttctac ggtcagcgtt ccgttcaggc ggatgtcttc ggaagaggcg
    13141 ccggccatga gcacgaagtc gccgggttcc accacccatt tcatgtcagc gtccagaagc
    13201 tccaggtgct tgcggtcgat ggtgaaggac agctcctggg cttcgcccgg ttcgaggtgg
    13261 atgcgctgga agcctgcaag attcttttcg taggtggtga tgctgctcag tacgtcgcgg
    13321 atatagagct gcactacttc atctccggca cgtttgccgg tgttggtcac cttcaggcgg
    13381 acggtggcag actcgttcgg ggtgatgact cggggggtga tgtcgaggtc ggagtactcg
    13441 aaggtggtgt agctcaagcc gtaaccgaag gggtagagtg ctccgttgat gcgtgacatg
    13501 ttgcccgtag gtcccggatt cttaccgccg tctatctgtg aagaaggttt gcaggggaag
    13561 ttgaagggga tttgccctac ggtcttgggg aaggtcaccg tcagctttcc accggggttg
    13621 tagtcgccga agaggatgtc ggccagggct gttccgcctt tggagccggg ataccaggct
    13681 tcgaggatag cggggacgaa cttgtctgcc cagttgatgg agagcgggcg tccgttgatg
    13741 agtatcagta cgacgggctt gcccgtggct tgtatggctt gaagcagttg caactgccga
    13801 ccgggcaggt cgaggctggt gcgcgatttg ttttcgccgc aggtgcgttg tccgccgccc
    13861 aatactacga cggcaacatc agcttgacgg gcattttcta cggctttgtc tatctcggct
    13921 tgttcgtcgt cggtcagcgg atagtctatg atttcacttt cgggccagtg ggcgtccacc
    13981 aggtcgcagc ctttggtgta gagcacctct gccttgcctt ttgtcttttc ttgaatgcct
    14041 tccagcacag tggtcacttc tacggcaagt gggccgtaat gggtcagcgc gtagccttct
    14101 tcattggcat tgggaccaca gacggcaatc ttcttggtgg agttgatgtc taagggcaat
    14161 agttcaccgg cattcttcag cagaacgatg gactcgcggg atgcctgcaa ggcaatggct
    14221 tcgttctctt ctttttccac ttcacggtcg gcatcggcaa ggtctgtctg atagggggca
    14281 tcgaacagac cgatgaggaa ctttacccga aggatgtcgc gcacgcggtc gttgatgact
    14341 tcttcgctca gtccgccttc cttcaccagt tcgcggaggg gaaggacgaa ggagtcgggc
    14401 gagcggaagg tgcagcgtac gttcagtccg gcttccacgc tttggcggac ggcttctttc
    14461 atgtctttgg cggtgccgtg cttggtgtag aggtattcta cggcgtcact gtcggatacg
    14521 acgtagccac ggaatcccat ttcgccacgc aggcgggtgg tgagccagta gtagctgccc
    14581 tgcacgggga tgccgtcgta atcgttgtac gaactcatta cgcccagcat gccggcttcc
    14641 cggatgacgc gtttgaaggg gtagatgtgt atgttctcca cttcgcgcgg cgacatttgc
    14701 gggtccacgc gtgccatgcc ttcgcgggcg cctttgttgt tactgtaagc ggcaaagtgc
    14761 ttgccggtgg cggccacttg gtggttgtgc tgcaagccgc gcaccatttc gatgcccagt
    14821 tcggctacga ggtaggggga ttcgccgtaa acttcttcgt agcgtcccca gcgctggtcg
    14881 cgtcctacgt cgaggatggg ggcgtagacg ttggtgtagc ccagcatgcg ggcttcgcgt
    14941 ccggtgatga gtcctacttg gcgaatcagt tcacggttcc aggtatgtcc cagtcccagt
    15001 tgggtgggga agttggtggc gcggtagctt tccacgccgc gtatgccttc gttggtaaag
    15061 tctacgggga tgccgagacg ggtatcttcc acaaagaacc gttgcacctc gttcagtgcc
    15121 caggcgtggc gcgaggcggg ccagacgtag gcattgtccg agggaggcag cccccattgc
    15181 tggaagccgt tcaggtgttc gtcgatggcg ccgataccgt ctttccagag cagctctttc
    15241 cattcggggg tggggaggtc gtctttcagt acgcgtttgt agccgtagag ggtgaccatt
    15301 tggcaggtct tttcgtccag cgtcatctgt tgcagcaggt tttcgatgcg tgcttcgagc
    15361 ggggcggagg ggtcttcgta cacgtctttc actccgtttt tgttgaagtc tatccaacct
    15421 ttgcggtaca tttcactttt caccggcttg taggttgccg gtgttttggc aggcttttgt
    15481 gcgcagagca gtgtgcttcc tccaagcagc agggttaggg caataaggtt cttcatgata
    15541 tgttctaaaa atctcttggt tattattgtt tcttttgttg acaaaaatac ggctaatgtg
    15601 tgaaataaag ggataaaata gtccgaagta tcggctttta ttgtccgaag ggtcttcctc
    15661 ttactaaaaa tatcctccaa gacgctaccg gggaattcaa atcattatta gacgaaacat
    15721 atcattcact tttaaaaaga aagagagaac actataataa cctgaaaagt agatgcaatc
    15781 gcggtgtata caagtattac ggctacatct gttaaacgag ggtgtattta tataacctta
    15841 attccgcaac actatagttt aacattattt ataagtgcct gagcaacaaa aagttgccca
    15901 ggattttgcc atgtc
//
