LOCUS       gnlProkkaFPDEOCMN_57    9937 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FPDEOCMN_57.
ACCESSION   gnlProkkaFPDEOCMN_57
VERSION     gnlProkkaFPDEOCMN_57
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 20:36:13
            Original ID  :: gnl|Prokka|FPDEOCMN_57
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9937
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9937
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3258:4656]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3259..4656
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..9937
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9937
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             251..1774
                     /gene_functions="other (smcogs) SMCOG1061:methyl-accepting
                     chemotaxis protein (Score: 191.6; E-value: 4.1e-58)"
                     /gene_kind="other"
                     /locus_tag="ctg57_1"
                     /transl_table=11
                     /translation="MFKKLNKMKIGARLKKSFRQIILIFGILSALVVVIMLYTINNYGT
                     ILDNYAYPQGDIAMAMNESAEVRAASRGIVGYDSDSLIESMKEQHEQAVKSFEEYLEKI
                     RPTMITKEGTACMDAIDKAWAEYKEVDAKVIEVGATTDTAKSLQAQQMMTDEAAPKYQA
                     LDDALQKLMALNISLGNAKRAQLRTVMIAALTIIIIVIAVSTIYSNSLSVAISKSIEKP
                     LNELKDRFITFAEGDIDSPLPTVESEDEIKELVSGVSAMSDRIRVIIKDSGRMLNEMSE
                     GNFAIDTECEEVYTGAFTDLLTGIRKMNEEIDTTVRGVDDASGQVLTGSTNLAEAAQSL
                     AEGATDQAASVEEMQATINELTSGIKTTAEELGTAYDEAYKYAEIAEGSRGDMEVLVQA
                     MSRINETSEKIGAIITQIEDIASQTNLLSLNASIEAARAGEAGKGFAVVADQIRNLAEQ
                     SAKSAVDSKALIEAAIHEVGDGNMYAEKASTSLREVVDGIQAIADSAKK"
     CDS             1804..1956
                     /locus_tag="ctg57_2"
                     /transl_table=11
                     /translation="MEQVEATAERIAEVVQNNSAAAQETSATSEELTAQATTLSGMVSV
                     FKLRQ"
     CDS             2649..2909
                     /locus_tag="ctg57_3"
                     /transl_table=11
                     /translation="MGNMDIEQRVISVFWNKFQFHAERLSETQKADSLLNPEIGFKAVD
                     LFVLYMELEKELHIKFDEKDVIDSRFDVYDNIINSVKRHLM"
     CDS             2985..3182
                     /locus_tag="ctg57_4"
                     /transl_table=11
                     /translation="MKKQLGKKAHVQEGTMTAFACDCISVCQSSAFCNCTSAATQSNTY
                     AASMGKIVATALSGSNYMWG"
     CDS             3259..4656
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_5"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     6.9e-20, bitscore: 60.8, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.6e-12, bitscore: 37.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.8e-15, bitscore: 46.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.2e-11, bitscore:
                     32.2, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELSNKPFIHLFRTRNQYYFYDANTCSIIRINETMYDILKNKENF
                     LELEQLKKLYENGFLQSKEDIIIEHPASSGIESYLDEGMQQLILQLTQNCNLRCKYCVY
                     SGSYKNRVHTNKRMTFEIAKEAIDYYYLHSRAADVVRIGLYGGEPLLEFDLIKKITEYC
                     EKIFAGKELRINMTTNATLLNEKIVDFLQKHNFDLMISLDGPESVQNKSRVFADNSHGT
                     FDVIIQKIEMIQKLYPQYLDKISFNAVIDEQNDFACSSNFFTYDFLKDAVVTAAGVSDR
                     DSVQEVSLRETFYINYNYELFKSFIVYAGELDNKYISKLIVSHKGLLISSIHDRVTKPY
                     RRKGICHPNGPCIAGYNRLFVTVEGKFYPCERVSETNEVYCIGDIKSGIETKKVLRLLN
                     TGKLTETECKNCWALNLCSICAADFGEDNDLSTSKKLQKCSVAKKEVEEHLVEYCTLRE
                     YGFNFEN"
     CDS             4668..5738
                     /locus_tag="ctg57_6"
                     /transl_table=11
                     /translation="MKVIVFPFDNYVRPLIEYEKLWHFEICGLISPMGFGINNMQMYEN
                     DKKYIIKSEMSEDNMAEMEALLVVESYHFVKFELILEQINLAAKNGKNIVLARKIDKNE
                     YSEVLDICEKSNVKLIEMPIESFKWEKNISGLQNINVPVIAIIENGVRCNAFEIEMQII
                     SVLLKENYKVSLISSRQFGNTENIHAFPGFMNGNGLNESEKIICYNQYLKYIEENEKPE
                     VIVVGIPGELLPLTKQKPGNFGIIAYEILNAVDPDFTILSLYKDEYKEEYFEEMNNLLH
                     YRYNVDADCFYLCNCSIDRFSINSVLPIKYLEHKNEEIEAQCIQYVHRVYCKNTYLDMT
                     DFLIETLTGYNEIQIF"
     CDS             5764..6528
                     /locus_tag="ctg57_7"
                     /transl_table=11
                     /translation="MSNTINVNYMTRAYNQYQQKIVTKDQEKEDTRFADSVKEKREGSG
                     SIVGNLKTGSVSAKDMTMEEYKQYIYNKISKIPMHPTRAGESISVTISEAGFEAMKNDP
                     EYEAWVLNDLQVGWSQPDKWSGICGGAFSTIYYGASKEECHAEMWSAGYNNGNGGKTFN
                     DKSKNSFWERRIENKKRIENQVKKQQEKKRIQEKQAERTAYEEYVQNKRLSAQDVRAGL
                     AAESSSSDRTVTTSQAVASYEANFIMAVRKWI"
     CDS             6549..7979
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 55.6; E-value: 9.1e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg57_8"
                     /sec_met_domain="Peptidase_S8 (E-value: 8e-11, bitscore:
                     30.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVQKIKIAIIDNGVDEAALGNEISGKVYVNEKKECVYDEADMSR
                     VRFAHGTICAAIIQKYLANSEIYSIRLLNEDGSGLIEHLKPALDWCIEKGIYLVNLSLG
                     TTHFRDKSLIRTLVNHYVSKGMCIVAATSNSGYESYPASFSNIIGVATHSSFFSDSLKR
                     LFLGINILGESEHTLRLYGVASVTQKCNSYAAPFVTAYIGMFFMEQGFQNITKLYKRFS
                     KKETMITISEKVEPDWICCAVIKANIKKSKADYYFDVVGIEEINRADTLIIDNLSDLEL
                     ATQYRKNVVYVGSEKIKETLDDCFYWCPNKRVQFIDRCTGNEQELDIPIIVFEVSEKID
                     VAFLLAEFKKDFADREYNIYTAGLEPEYVLYGLEYVPEQCLSKVKTVKEFIYWQTFYMQ
                     SDGVLFCISEGKHSLIEPLFSDIDVMVRIENINNIYLAEIQNEDIVVLKISDCEIDKDF
                     VEKVTNCLVRILTEEEDG"
     CDS             7972..9678
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 256.5; E-value:
                     8.8e-78)"
                     /gene_kind="transport"
                     /locus_tag="ctg57_9"
                     /transl_table=11
                     /translation="MDNKEAVKRLLLLLGRYKKTIVVIVGCLLVSTGLNLCVPLISRRI
                     MDDGFIGGNKKLLIELVLVSMVIYTINSLIDIVKEKKRVDISAKIQYFLSEQSFSHLMK
                     LRVNYFNNTNYAETLNNINTDINQMTSIADSSVFFVITQAFSMTGGIIGLFIIDFRMTV
                     LVLLFIPIKCVVMKYFAKKQKQIMDEFIKRNQEYAKWFGDTVGGVREVKLFNILDKKHE
                     EFVLNQNNIIEKQKQMNMLGQWNTIIDSIMVQFLSTLLYILGANLVFDMKLSVGSVFAF
                     ITYSAYVTGPISAILNIGYLLSGIIPSTKRYYAFMELEEETDNGKKTDLCPNDLRLQKV
                     SFAYERDKCILKNIDILFAKSSKTAIIGRNGSGKTTIINLLTRMYEPTSGEILLGAENI
                     SELPLPEYRNMVSVVSQQIYLFNDTIRNNICLYKQIDDTVIEAACKDSGLEDFIKEVSL
                     DHVVGQNGAMLSGGQKQKIALARALVHDKPIIIFDEATSNTDAYSEQQINGLLDTRLKD
                     KTVIVITHKKEILSKVDQIVVLKEGVVADLGRYDDLIGKSDELNVMLEKAE"
ORIGIN
        1 tcgttgtttt tgttcggtca taaagagtgc tccttcgtgt atttattata gattatatga
       61 ccttaaaaaa tctgtccagt taattgtaac ctatccagta tatggcacat tttggttatg
      121 cgttagtgca taattgaaat gtgcctttta tattgaaacc accttgatgt acggtcatat
      181 attgacttgt atatacatat tgatgggaca acaaagaacc attttatcca ttaggaagga
      241 gacaagacaa atgtttaaga aacttaacaa aatgaagatt ggtgcacgac tgaaaaaatc
      301 tttcagacag attattctca tttttggaat attatcagca ctggttgtag tgattatgct
      361 ttatacgata aacaactatg gaacgatact ggataattat gcgtatccac agggagacat
      421 tgctatggca atgaatgaat cagcggaagt aagggctgcc tcaagaggta ttgtaggtta
      481 tgattcagat agtctcattg aaagtatgaa agaacagcat gaacaggctg ttaaatcgtt
      541 tgaggaatat ttggaaaaaa tacgcccaac aatgataaca aaagagggaa ctgcctgcat
      601 ggacgctatt gataaagcat gggcagagta taaggaagtg gatgcaaaag taattgaggt
      661 cggtgcaacg actgatactg cgaaatcatt acaggctcag cagatgatga ccgatgaagc
      721 agcaccaaag tatcaggcgt tggatgatgc tttacagaaa cttatggctt tgaatatttc
      781 acttggaaac gctaaacgtg cacagttgag aacggttatg atagctgcat tgacaattat
      841 aataattgta attgcagtat caacgattta ttcaaacagt ctttccgttg caatatcaaa
      901 gagcattgaa aaaccattaa atgaattaaa ggacagattt attacatttg cagagggtga
      961 catagattct ccacttccaa cggttgagtc tgaggatgaa attaaggaac ttgtatctgg
     1021 tgtatctgca atgtcagaca gaattagagt tataattaaa gattctggca gaatgttaaa
     1081 tgaaatgtca gaaggtaatt ttgcgattga tacagagtgt gaggaagtat atacaggagc
     1141 atttaccgat ttgctgacag gcataagaaa aatgaatgag gagattgata caactgtaag
     1201 aggggtagat gatgcatcgg ggcaggttct tacaggttcc acaaaccttg cagaagcggc
     1261 acagtcttta gcagaaggcg caacggatca ggcggcatcg gttgaggaaa tgcaggcaac
     1321 tatcaatgaa cttacaagcg gaataaaaac aacagcagaa gaattaggaa cagcttacga
     1381 tgaagcctat aagtatgcgg agattgcaga aggcagtcgt ggagatatgg aagtattagt
     1441 gcaggctatg tcacgcataa atgaaacctc tgagaagata ggagcaatta tcacacagat
     1501 tgaagatatt gcaagccaga caaatcttct ttcattaaat gcttcgattg aggcagcaag
     1561 agctggagaa gccggaaaag gttttgctgt tgttgcggat cagatcagaa accttgcaga
     1621 acagagtgca aaatcagcgg tggattcaaa agcacttatt gaggcggcta ttcatgaggt
     1681 tggagatgga aatatgtatg cagagaaagc ctcaacttca ttgagagaag ttgtggatgg
     1741 catacaggcg attgcagaca gtgcgaaaaa ataaaagaaa tttccattga acaggcagac
     1801 agtatggagc aggtagaggc aaccgcagaa agaattgctg aagttgttca gaataattcg
     1861 gctgcggcac aggaaacatc agcgacgagt gaagaactta cagctcaggc tacaacactt
     1921 agcggtatgg tttcggtatt caaattaaga cagtaagaat agacagagtt tttagtggat
     1981 gattgttttt tacacagtta aagaataatc gtccactttt ctgttttggg caagaaaatg
     2041 ttttttactt ttagttcggt tatatggtta tttataataa aaatatagaa acaatgcgtc
     2101 gtttaataga tgatatatga agtatatgtt ggaggggtga attaaaatat aagtcaaaat
     2161 tttttatact ataaatgagc aagttcgtga ttttgcataa aagaaagaca ccttaaatcg
     2221 tttgtgttgt gtaatgaaag tgatgaaaca aacatcgacc aacggaaaca gtatcgatat
     2281 ctgtaccaac gtgcaatgga cagcaaggat tttgattcgt tcatgaaatt ggcagtgtag
     2341 ttttatgtaa tttttcaaat ttgcttattt atagttctta aattaagaag gataacttta
     2401 tgcttttgct tttgcttttg actatatttt gagtgtcatt ttctgctgta aatggtcatt
     2461 ttctgcaaag ctactttgta gtatgatgtt aattgcttat aattaaagta tcgaacaaaa
     2521 atagaaagga gaatgcagta tgggaattaa tgtagtatca tcgtatgcca atacatacac
     2581 ttacggaaat gtaaaagacg aaagcataaa aggattttag catacgaaaa gaatgataga
     2641 ggaaagttat gggtaatatg gatatagagc aaagggtaat ttcggttttt tggaataaat
     2701 ttcaatttca tgcagaaaga ttatctgaaa ctcagaaagc ggatagctta cttaatccag
     2761 aaataggatt taaagcagta gatttgtttg ttttgtatat ggaattagaa aaggaactgc
     2821 atattaaatt tgatgaaaaa gatgtaattg atagcagatt tgatgtgtat gataatatca
     2881 taaattcggt aaagagacat ttgatgtaag gtatagttgc tcatacataa tgagaatact
     2941 atatgacagg tttctgtcaa tattgaagaa aggaggattg tcctatgaaa aagcaattag
     3001 gaaagaaagc tcatgtacag gaaggaacaa tgactgcatt tgcatgtgat tgtatctctg
     3061 tatgccaatc aagtgcattt tgtaactgca catctgctgc aacacagtct aatacatatg
     3121 cggcaagtat gggcaagatt gtggcaactg ctttgtcagg ttctaattat atgtggggct
     3181 aattcagagt agtaagtttt acggtgactg gcagtaattt tattgctgtc agtcatttgc
     3241 aaacaaagga gatacaatat ggagttaagt aataaacctt ttattcattt atttagaacc
     3301 agaaatcaat attattttta tgatgcaaat acatgttcaa ttatcagaat taatgaaaca
     3361 atgtatgaca ttttaaaaaa caaggaaaat tttttggaat tagagcagtt aaagaaatta
     3421 tatgaaaacg gctttttaca atctaaagaa gatattatta ttgaacatcc agcgtcttct
     3481 ggtattgaaa gctatcttga tgaaggtatg caacaattaa ttttacagtt aactcaaaat
     3541 tgtaatttaa gatgtaaata ttgcgtatac tctggaagtt ataaaaaccg tgtacatact
     3601 aataaaagaa tgacatttga aatagcaaaa gaagcaattg attattatta tttgcatagt
     3661 cgggcagcgg atgtggtgcg tattggacta tacggtggag aacccttatt agagtttgat
     3721 ttaataaaga aaattactga atactgcgaa aagatttttg caggaaaaga attaagaata
     3781 aatatgacta ctaatgcaac tttattgaat gaaaagattg ttgattttct acagaaacat
     3841 aattttgacc taatgattag tcttgatggt ccggaatcag tgcaaaataa aagtagagta
     3901 tttgcagata atagtcatgg aacatttgat gttatcatac aaaaaataga gatgatacaa
     3961 aaattatatc ctcaatattt ggataagatt agttttaatg cagttattga tgaacaaaat
     4021 gattttgcgt gtagtagtaa tttttttaca tatgatttcc taaaggatgc agtggttaca
     4081 gctgctggag ttagcgatag agattctgtt caggaagtat cattgcgtga aactttttat
     4141 ataaattata attatgagct ttttaagagt tttattgttt atgcaggtga gttggataat
     4201 aaatacatct caaaattaat agtgtctcat aaaggactgc ttataagttc aatacatgat
     4261 agggtgacaa aaccatatcg cagaaaagga atatgccacc ctaatggtcc atgtatagcg
     4321 ggatataaca gattatttgt aacagttgaa ggaaaatttt atccttgtga aagagtaagt
     4381 gaaacaaatg aggtttattg tatcggagat ataaaaagtg gaattgaaac gaaaaaagta
     4441 ctgcgcttat taaatacagg aaagttgaca gaaacggaat gtaagaattg ttgggcatta
     4501 aatctttgta gtatttgtgc agcagatttt ggtgaggata atgatctctc aacatcaaaa
     4561 aaactacaga aatgttctgt tgcaaaaaaa gaagttgaag aacatttagt agaatattgt
     4621 acattaagag agtatggttt taattttgaa aactaggtgg taatcaaatg aaagtaatag
     4681 tttttccctt tgataattat gttagaccgt tgatagaata tgagaagttg tggcattttg
     4741 agatatgtgg tcttatatcg ccaatgggtt ttggaattaa taatatgcag atgtatgaaa
     4801 atgataaaaa gtatattatt aaaagtgaaa tgagtgaaga taatatggca gagatggaag
     4861 cacttcttgt tgtcgaatca tatcattttg tcaaatttga attgatatta gaacaaataa
     4921 atttggcagc aaaaaatggg aaaaatattg tattggcaag aaaaatagat aaaaatgaat
     4981 attcagaagt tcttgatata tgtgaaaaaa gtaatgttaa attaatagaa atgccaatag
     5041 aatcttttaa atgggagaaa aatatttcgg gtctacaaaa tattaatgtt ccggtaattg
     5101 cgattataga gaatggagta agatgtaatg cattcgagat tgaaatgcag attattagtg
     5161 tgttattaaa ggaaaattat aaagttagtt tgatttcgag taggcaattt ggtaataccg
     5221 agaatataca tgcttttcct ggatttatga atggaaatgg tttaaatgaa agtgaaaaaa
     5281 taatttgcta caaccaatat ctaaaatata ttgaagaaaa tgaaaagcca gaggtaattg
     5341 ttgttggaat accgggtgag ttacttccac ttacaaagca aaagccagga aattttggaa
     5401 taatagcgta tgaaatttta aatgccgtag atccggattt tacaatctta tcgctttata
     5461 aagatgaata caaagaagag tattttgaag aaatgaacaa tcttttgcac tatcgttata
     5521 atgtagatgc agattgcttt tatttatgca attgttcaat agacaggttt tcgattaatt
     5581 cagttttgcc gataaagtat ttagaacata agaatgagga gatagaagca cagtgtattc
     5641 aatatgttca tagggtatat tgcaagaata cctatcttga tatgacagat tttttaatag
     5701 agacactgac aggttataat gagattcaaa tattttaaaa ttcttaacaa ggaggagatt
     5761 actatgagca atacaattaa tgtgaactat atgacaaggg cttacaatca gtaccagcag
     5821 aaaattgtga ctaaagatca ggagaaggaa gatacaaggt ttgcggatag tgtaaaagaa
     5881 aagcgcgaag gtagtggaag tatagtgggc aatttaaaaa caggttctgt gtctgctaaa
     5941 gatatgacaa tggaggaata caagcagtat atttacaata aaatatctaa aattccaatg
     6001 catcccacaa gggcaggcga gtcaatatct gttacaattt cagaggcggg gtttgaagcg
     6061 atgaagaatg atccagagta tgaagcatgg gtattaaatg atttgcaggt gggctggtca
     6121 caaccggata aatggtccgg tatatgtgga ggagcgtttt ctacaatata ttatggagca
     6181 tcaaaagaag aatgtcatgc tgaaatgtgg agtgcaggtt ataacaatgg aaatggtggg
     6241 aagactttta atgataagtc aaaaaatagt ttttgggagc gtagaataga aaataaaaag
     6301 agaatagaaa atcaagtaaa gaaacaacag gaaaaaaagc ggattcagga aaaacaagca
     6361 gaaagaacag cttatgaaga atatgtgcaa aataaaaggt tatcagctca ggatgttaga
     6421 gcgggattgg cggcggagag tagttcgtct gataggactg tcacaacaag tcaggcagta
     6481 gcttcttatg aggcaaattt tataatggca gtaagaaaat ggatttaatg aatttactat
     6541 aagaggcgat gttagtgcag aaaataaaga tagcgattat tgataatggt gtagatgaag
     6601 ctgctttggg taatgaaata tcaggaaaag tttatgttaa tgaaaaaaaa gagtgtgttt
     6661 atgatgaagc ggacatgagt agagtaagat ttgctcatgg gacaatatgc gcagccatta
     6721 ttcaaaaata tttagcaaat tcagaaatat acagtattcg acttctaaat gaagacggaa
     6781 gtggcttaat agaacattta aaaccagcat tagattggtg tatagaaaaa ggtatttatt
     6841 tggttaattt gagcttaggc actacacatt ttagggataa gtcattaata agaacattag
     6901 taaaccatta tgtgagcaag ggaatgtgca tcgtagctgc aacatctaat agtggatatg
     6961 aatcatatcc ggcttctttt tcaaatataa taggtgttgc aacgcattcc tctttttttt
     7021 cagattcttt aaagagactg tttcttggga taaatatact tggtgagtct gaacatacgc
     7081 tgcgattgta tggagttgca tctgttactc agaaatgtaa cagttatgca gctccctttg
     7141 taactgctta tattggtatg ttttttatgg aacagggatt tcaaaatatt accaaattat
     7201 ataagaggtt ttctaaaaaa gaaacaatga ttacaatatc tgaaaaggtt gaacccgatt
     7261 ggatatgctg tgcagtaatt aaggcaaata ttaaaaagag taaggctgat tactattttg
     7321 atgttgtagg aattgaagaa ataaatcggg cagatacact tattattgat aacttgtcag
     7381 atttagaact agctactcaa tatagaaaaa atgttgttta tgttggaagt gagaaaataa
     7441 aggagacatt agatgattgc ttttattggt gtccaaataa gagagtacaa tttattgata
     7501 gatgtactgg aaatgaacaa gagttagaca ttcccataat tgtattcgaa gtaagtgaga
     7561 aaatagatgt agcgtttctg ctcgcagagt tcaaaaaaga ttttgctgat cgtgagtata
     7621 atatatatac cgcagggtta gaaccagaat atgttttgta tgggttagaa tatgtaccag
     7681 aacaatgcct gagtaaagta aaaacggtta aagagttcat ctattggcaa acgttttaca
     7741 tgcaaagcga tggtgtatta ttttgtatat cggaaggaaa acatagtctt attgagccac
     7801 tttttagtga tatagatgtt atggtaagaa ttgaaaatat aaataatata tatttagcgg
     7861 aaattcaaaa tgaagatata gttgtattga aaataagtga ttgtgaaata gataaggatt
     7921 ttgtcgagaa agttacaaat tgtcttgtaa gaatattgac ggaggaagaa gatggataac
     7981 aaagaggctg taaaaagatt acttctgtta ctaggcagat acaaaaaaac aatagttgta
     8041 attgtcggtt gtctgcttgt ttctaccggg ttaaatctat gcgttccgct gatcagcagg
     8101 cgaatcatgg acgatggctt tattggcgga aataagaaat tattgataga gctggtcttg
     8161 gtgtctatgg taatctacac tataaattcc ctcatagata tagtcaagga aaagaaacgt
     8221 gtagatattt cagcaaagat acaatatttt ctttcggaac agtctttttc acatcttatg
     8281 aagctgcggg taaactattt caataacaca aactatgcgg agactttgaa taatatcaac
     8341 acggatatta accagatgac atctattgct gacagcagtg tttttttcgt aattacgcag
     8401 gcgtttagca tgacaggcgg cataataggt ttattcataa tagatttcag aatgacggta
     8461 ctggttcttc tgtttatacc tattaagtgt gtggtaatga aatactttgc aaaaaagcaa
     8521 aaacagatta tggacgagtt cataaaaagg aatcaggagt acgcaaaatg gtttggagat
     8581 actgttggag gggtacgaga agtcaagctg tttaatatct tggataaaaa gcatgaggag
     8641 tttgtactta accagaacaa tattatagag aaacaaaagc agatgaatat gttagggcag
     8701 tggaatacga taatagatag tatcatggta cagtttcttt ctacattgtt atatatactg
     8761 ggcgcaaatt tagtgtttga tatgaaactt tcagtaggta gtgtgttcgc tttcattaca
     8821 tatagtgctt atgttaccgg accgatttct gcaatcctaa atataggata cctgttatca
     8881 gggattattc cgtcaacaaa aagatattat gcgtttatgg aattggaaga agaaacggat
     8941 aatggaaaga aaacggatct atgtccaaat gatttgagat tgcagaaggt ttcttttgcg
     9001 tatgaaaggg ataagtgcat tttgaagaat attgatatat tatttgcaaa atccagcaag
     9061 acagctataa ttgggcgcaa tggttcggga aagacgacaa tcatcaatct tcttacgaga
     9121 atgtatgagc cgacaagtgg tgaaatactg ttgggagcag aaaatatttc agagctgcca
     9181 ttgccagaat accgaaatat ggtatccgtt gtgagccaac aaatctattt attcaatgac
     9241 acaataagga ataatatctg tctgtataaa caaatagatg atacggtgat agaagctgcc
     9301 tgcaaggaca gcggacttga agattttata aaagaggttt ccttagatca tgtggtagga
     9361 cagaatgggg caatgctctc cggcgggcaa aagcagaaaa tagcccttgc aagggcattg
     9421 gtgcatgaca agccgattat tatatttgat gaagctactt caaacacaga tgcttattca
     9481 gaacagcaga taaacggact gcttgatact cggctaaaag acaaaacagt gatagtgata
     9541 acacataaga aagagatatt gagcaaagtg gatcagatcg ttgtactgaa ggagggagtg
     9601 gttgcagatt tagggagata tgatgatttg atagggaaaa gtgatgaact aaatgttatg
     9661 ttggaaaaag cagaataaat ataagaaaat cttttcagag tagcaagtct tttttgcttt
     9721 tgggacaaaa agtattattt ctggcagaaa atgtgaaata ttattagatg cttgtcggta
     9781 aaaaagaaaa atagagagaa tttgcatcat gcaggttaat tctaattatt ctatgaatgg
     9841 tgtgccgtat gaaactagtg tactgacata ttgatattta gttaaatatt tctggctgtt
     9901 attgccgttt tatggtacaa taaaagaaac ggcggtg
//
