LOCUS       c00003_gnlPro..        15672 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OHBFBPDH_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 04:07:42
            Original ID  :: gnl|Prokka|OHBFBPDH_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15672
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15672
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2528:5672]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2529..5672
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15672
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15672
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             466..981
                     /locus_tag="ctg3_1"
                     /transl_table=11
                     /translation="MLAWLPFFLISLMFIVLLYACARSARTNIQRFKQLSLIAFLWVLT
                     AFCYTPTSYNFGTQLVIQYIQWGPVKLNVIPFQQLDIEFWLNVLLTVPLGGLLAWNFPD
                     LPWRRFIWLGFLTGLTLELGQFILDWLVNLKRWVDIDDVITNWAGVIIGAAGYKIARHV
                     PGLRWLQK"
     CDS             complement(1149..2138)
                     /locus_tag="ctg3_2"
                     /transl_table=11
                     /translation="MRMLEKIEQYIDSCIEAGDIYGASFSLITPKGINQYYHGKQGRDE
                     FAVGLDPAMIYDLASVTKVVGTTTRIFQLLSDHTIHLTDSVARFLPGFTHPEITIKNLL
                     LHNSGLPADIDNLDKMQREDLIKAVYDAPLVTAPGTTYVYSDLGFILLGWIIRAVDGSL
                     ARSIQDHVCYPLAMTNTGYNLNRPKIRFVPTEFDPRRGQIQGQVHDYKAFLLNGESGHA
                     GLFSTLTDLSVFIEMMLNFGEYQGKRVLDENVFDWLGEYDENGRTLGWERRAGRHQYFH
                     TGFTGPAVAFDLDRQIGLVVLTNRVYPTSDNQVWNQDRKRVFDLFFES"
     CDS             2529..4814
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_3"
                     /sec_met_domain="Gly_radical (E-value: 5.3e-40, bitscore:
                     126.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 9e-247, bitscore:
                     810.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LDSNYGGEKMITSEKTTKPAAWKGFKGGHWQEEINIRDFIQNNFT
                     QYNGDESFLAGPTAATKTLNDKVLELKKQERAAGGVLDADTKVVATITSHGPGYIQKDL
                     EKIVGLQTDKPLKRAFMPFGGIRMADDALKSYGYTPDEENDKIFTEYRKTHNQGVFDVY
                     TPDMRKARHYKIITGLPDAYARGRLIPDLPRVAVYGIDRLMEDKANDFAHIGDGELTDD
                     VIRLREEVQDQYRALADMKKMAASYGYDISKPATNAQEAIQWMYFAYLAAIKTQNGAAM
                     SVGRIDTTMDIFIQRDLDNGVLDESQAQELIDQFVMKLRMVRFIRTEEYNSLFSGDPIW
                     ATLSMCGLGVDGQHHVTKTAFRILKTLDNMGAAPEPNITILWSDRLPEDFKRYATEVSI
                     DSSTIQYENDDLMRVQWGTDYYGIACCVSAQPIADGIQYFGARANLAKAILYAINGGRD
                     EIAGDQVGPAYEPITSEYIDYDEFMKKLDKQMDWLADTYVNSLNAIHYMHDKYYYEAAQ
                     LALKNTDLDRTFATGISGLSHAADSISAIKYGHVKVIRDERGIAVDFKADNDYPRYGNN
                     DDRADDIAKWLVKELYSKMNTHHLYRNAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEP
                     FSPGANPAYGAEKSGALASLLSTAKLPYRYATDGISNTFGVTPNTLGHDLESRKDTLVN
                     MLDGYMKNDGMHLNINVFNKDTLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVI
                     SRTFFESM"
     CDS             4851..5672
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74; E-value:
                     4.8e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_4"
                     /sec_met_domain="Radical_SAM (E-value: 8.4e-28, bitscore:
                     88.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKQVSTTQAAAKEPLIGYVHSIETFGSVDGPGIRYVAFLQGCH
                     MRCQYCHNPDTWKLNVGDQMTADEILEDAAKYRAFWGKTGGITVSGGESLVQIDFILDL
                     FEKAKAMNISTCLDTSGQPFTREQPFFDKFERLMKVTDISLVDIKHIDSAKHKQLTQYG
                     NENILDMIQYMAQHHDDMWIRHVLVPQRTDYDEDLKKLGDYIAKIPNDVVQKVEVLPYH
                     TLGVKKYHEMKIKYRLEGIESPTQDRVANAEKLLHTADYNGYKTWMPLPKL"
     CDS             5760..5912
                     /locus_tag="ctg3_5"
                     /transl_table=11
                     /translation="MHVLLAGISTVARKKGAASKPATSFLNHALSNDRQPLDWLRTGRP
                     LTMNA"
     CDS             complement(5895..6224)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FeS_assembly_P"
                     /gene_functions="other (smcogs) SMCOG1048:Iron-sulfur
                     cluster assembly protein (Score: 66.9; E-value: 4.7e-21)"
                     /gene_kind="other"
                     /locus_tag="ctg3_6"
                     /sec_met_domain="FeS_assembly_P (E-value: 1.7e-21,
                     bitscore: 66.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGRDTMTTTFKDRAFEALGHVIDPELGIDLVNLGLIYDAQLTAE
                     GTAEITMTLTIAGCPLTEWLAKDIHDELIKLPEVNNIEIEIVWEPAWNESMMSREARME
                     LGIHS"
     CDS             7266..8186
                     /locus_tag="ctg3_7"
                     /transl_table=11
                     /translation="LKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAADLGINY
                     VDSADIYGGGQSSTIFGQALKQAHVSRDQLYIQSKGGIVPGKRYDFSKQHILAAVDGEL
                     QRLGVDYLDTFLLHRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQAALN
                     QRLIINQLQFGIMHTGAIDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGN
                     FAGIFLDNPKFPELNNAMQALADEKQVTKSAIATAWILRHPAHFQVILGTMNPEHLAQN
                     AAGADVTLSRQEWYDIYFAAGNDLP"
     CDS             8356..8550
                     /locus_tag="ctg3_8"
                     /transl_table=11
                     /translation="MTSTCTICERIKLIQAHQNPYFVYELTTGYVVLADSQYFEGYTLF
                     LAKHHVTELHHLPAHEKLR"
     CDS             8560..8880
                     /locus_tag="ctg3_9"
                     /transl_table=11
                     /translation="MSIVQEACAQAFHADKMNIELLGNGDAHVHWHLFPRHNGDTPNPG
                     PVWWTPLETIYGDDVSLDIPRLSRLKRTLSVAIEATLNAREAELQALEALTRPASHRID
                     SN"
     CDS             complement(8975..9220)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_10"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 4.6e-05, bitscore:
                     13.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAPLSSFEKNIPAVTELLAVDAELQTFFVALTPGYQREWARFI
                     FGTKAQATKERHIEVMKTVFRAGYKSKRAYDSRPDK"
     CDS             9393..9821
                     /locus_tag="ctg3_11"
                     /transl_table=11
                     /translation="MPKFDITLISPERAKAMLTEYKEQRKNSVPHLAHPGRYILPDYKL
                     TRRRAAFKIVKHTFLTPHYKSYVAMDSDNGHTLWFHNFGSLTEALFWLETGLKISDTDS
                     HSNYKEWMAKHTTEIETFKDLLREQKHKQGPKTKKKAK"
     CDS             complement(9924..10565)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_12"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 3.1e-20, bitscore:
                     63.8, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAISNGHVSFKRPAWLGDSITANNGLATVHYHDILAADWDVERSD
                     NLGISGSTIGSRYDAMAMRYQAIPEDADFIAVFGGVNDYGRDQPLGQYGDCDMTTFYGA
                     LMMLLTGLQTNWPTVPKLFISAIHIGSDFGGSFSAVTNGLGYRQSDYEAAIAQMTADYG
                     VPHLSLYRDAGMTFAIPAQAAIYSVDTLHPNNAGHRVIARKLQSFLDSHF"
     CDS             complement(10990..11277)
                     /locus_tag="ctg3_13"
                     /transl_table=11
                     /translation="LLSGISPLSIGRNAFHSGQYSNGGRRYTQLLMNLSLFSINSNFIN
                     QLLGRKDIGIARYFGITIVIIEHLNKVVRVTLTSRLKFRYQNSQRPIVPS"
     CDS             complement(11581..13107)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BCCT"
                     /gene_functions="transport (smcogs)
                     SMCOG1001:betaine/carnitine/choline family transporter
                     (Score: 401.8; E-value: 1.1e-122)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_14"
                     /sec_met_domain="BCCT (E-value: 4.1e-123, bitscore: 401.8,
                     seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNWLTNNMSWLYMSVYVITFIFFIYLGFSKLGKTKLGDPDDKPEF
                     STYHWGSMVYATGIDASILMLSMVDPLRYLQSPSFGVKPFSTSAYNYAHMLGQFNWGPM
                     AWMMFAPATIAIAYAMYVKHIKVQRLSAAISVLQGPGKGKQIARNTIDFLVIIGIMGGV
                     GTSVGMEIPVISKVLSAVTGIADTMTLKLGLFALLFVIFAMAVFNGLKKGIGRLSAAHV
                     WLAIGFLIVVLIVGPTLYILNSETNSIGLFVNKFITLSTNTAPNGHATAMQRQTIFYWG
                     WWLSFMPVMGLFIARISRGRTIRQVLGGMLLWGSLGCVSFYAILGGYALYLQRMGIVNL
                     VHILNTQGQAAVIAAVLSTLPLKMIMLALYCLSCFIFLATTVSSFAFITSSFTSKKLAA
                     GEQPSRFNRMSWVVIFLVFSLGLVTVGGFESIQSICAMSGFPLTIVALVLLYSIHHDLT
                     TDPVKEAAKANAKAAELARRKRLARDVEITTKTDYARERRTARKRETEAD"
     CDS             complement(13599..13745)
                     /locus_tag="ctg3_15"
                     /transl_table=11
                     /translation="LYKPTCAVQVVTCYPVLSAFLVHQAINLTVVRWAYLVIQGGYLLA
                     RAV"
ORIGIN
        1 agttctaaaa agctcattta atgttgtact aaaatttatt tgctagcgaa ttgacttcgc
       61 aaatgttttg ctcttgattc aaaatcaaga gaccctacac atttgattcg tcgaaacttt
      121 gttcagtttt caaagatcta attccgtgtg ttaatcgctt aacacaactt aatcatcata
      181 acatcttaat caatatcttg tcaacaactt tttttaagaa gtaacttgat taatttgtca
      241 tagttgccgt tgcgacaaca gaaactatct taccaattac tgaagaaatt gtcaacaact
      301 aatttcaata attatttggt ggtgagatgc atctgccgta gcagcaacgt ttactaatat
      361 accaattgaa gtaaaaagtg tcaacacttt ttctgaattt ctttttatta atagtcaaac
      421 cagctttctt tctctatact atttaattaa aggagcgact aaattatgct agcttggcta
      481 ccattctttt tgatttcatt aatgtttatt gttctactat acgcttgtgc gcgatcagcg
      541 cgcacaaata tccagcgttt taagcaactc agtttaattg cctttctctg ggtcttaact
      601 gctttttgct atacacctac cagttacaat tttggtaccc aactcgttat tcaatatatt
      661 caatggggac ccgttaagct gaacgtgatt cctttccaac aacttgacat tgaattttgg
      721 ctcaacgttc tcctcactgt tccattgggc ggtttactgg catggaattt tcccgacttg
      781 ccttggcgtc gttttatttg gttgggattt cttacggggc taacactcga gctgggacaa
      841 ttcatccttg actggttggt taacctcaaa cgttgggttg atatcgatga tgtcatcaca
      901 aattgggctg gtgtcattat cggtgccgct ggttataaaa ttgcacgtca tgttcccgga
      961 cttcgctggt tgcaaaaata acgtatatat agaagcaaaa agcaaaacaa cgtttgttta
     1021 gcacccacaa gtgccaaaca cttcagcgct ctagctgtta tgaaatcgta attaaataag
     1081 cgtcgcagcc acttaaggtt gcgacgctta tttaatttaa ctactaacta ttaatgaagc
     1141 tgccatcatc aggattcaaa aaacagatcg aatactcgct tacgatcttg gttccagact
     1201 tgattgtcac tagttggata aactcgattt gttaacacaa ccagcccaat ttgacgatcc
     1261 aaatcaaaag caactgccgg gccagtaaaa ccagtatgga aatattgatg tcgtcccgca
     1321 cgtcgttccc aacctaacgt ccggccattt tcgtcatact cgcctaacca gtcaaagaca
     1381 ttttcatcca gcacccgttt gccttgatat tcaccaaagt ttaacatcat ttcaataaat
     1441 acggataaat ccgtcagcgt tgagaacaag cctgcgtgac cactctcacc attcaacaaa
     1501 aaggctttat aatcatgcac ctgtccttga atctgacccc gccgcggatc aaactccgtc
     1561 ggcacaaacc gaatcttcgg acgatttaag ttataacccg tattggtcat cgctagtgga
     1621 tagcaaacgt ggtcttgaat actccgagcc aatgagccgt caaccgcacg aataatccat
     1681 cccaataaaa taaatcccag gtctgaatag acatacgttg tccctggcgc cgtgacgagt
     1741 ggcgcatcat aaaccgcttt gatcagatct tcacgttgca tcttatccag gttatcaata
     1801 tctgccggta acccactatt atgaagtaac aagtttttaa tcgttatttc aggatgagtg
     1861 aacccaggta aaaaccgggc aaccgagtcc gttaaatgaa tcgtgtggtc cgataacaac
     1921 tgaaaaatcc tcgtcgtggt ccctacaacc ttagttaccg atgctaggtc ataaatcatc
     1981 gcaggatcta agcccacggc aaactcatcg cggccctgct taccatgata gtattgattg
     2041 atacctttag gggtgatcaa gctaaacgac gccccataaa tgtcgccagc ttcaatacaa
     2101 ctgtcaatat attgttcaat tttttcgagc atccgcatta cgcccacctt tcactacatt
     2161 cactagtttc tgcttatctt ctttatgata acgaacttcc tcataaaatc aacggcaaac
     2221 gcttttaaca ccctccacac ctcgttgcac tttttattaa ttaactagtt aaacacttgt
     2281 tacattatgg acaatattcc acttatatat caaaacaagt cttgttttta gccgttttct
     2341 aaatataatt aagtgaatta ccaatgccta tctagctatg taagtactgt tatatcaacg
     2401 ttaatagtca acttttcaat aatagattgc aaaaaaataa cccaaacgtg aaataaatcg
     2461 cctgaaagcg gttacaaatc cagcaaaaaa tgttatgatt caaatataga attttatcaa
     2521 tcatttgatt ggattcaaat tatggaggcg agaaaatgat tacatcagaa aagacaacaa
     2581 aaccagcagc ttggaaaggt ttcaaaggcg ggcactggca ggaagaaatc aacattcgtg
     2641 attttattca aaataacttc acacagtaca atggcgacga aagcttcctg gccggaccaa
     2701 cagccgctac taagaccttg aatgacaaag tcttagaatt aaagaaacaa gaacgtgccg
     2761 ctggtggtgt gttggatgct gatactaaag tcgttgcaac gattacttca cacggccctg
     2821 gttatattca aaaagatctc gaaaagattg ttggtctcca gactgacaag cctttgaagc
     2881 gggccttcat gccatttggt ggtattcgaa tggctgatga cgctttgaaa tcatacggtt
     2941 atacccctga tgaagaaaac gacaagattt tcactgaata tcgcaagact cataaccaag
     3001 gcgtcttcga tgtttatact cctgacatgc ggaaagcacg tcactacaag atcatcaccg
     3061 gactaccaga tgcatacgca cgtggccgtc tcattcctga tcttccacgg gtcgctgttt
     3121 atgggatcga tcgtttaatg gaagacaaag ctaatgactt tgcccacatt ggtgatggtg
     3181 aattgactga tgatgttatt cgcctccgtg aagaagttca agatcaatac cgtgctttag
     3241 cagatatgaa gaagatggct gccagttatg gctacgatat tagcaagcct gcaactaatg
     3301 ctcaagaagc tattcaatgg atgtacttcg cttacttagc tgctatcaag acccaaaacg
     3361 gcgctgcaat gtccgttggc cggattgata caacgatgga catcttcatc caacgtgact
     3421 tggacaatgg tgttctggac gaaagccaag ctcaagaatt aattgatcaa ttcgtcatga
     3481 aactacggat ggttcggttc atccgtactg aagaatacaa ttctctcttc tctggtgacc
     3541 caatctgggc aaccttatca atgtgtggtt taggcgtcga cggtcaacac catgtgacta
     3601 agaccgcttt ccggatttta aagactttgg acaacatggg cgccgcacca gaaccaaaca
     3661 tcacgatttt atggtcagac cgcttaccag aagacttcaa acgttacgca actgaagttt
     3721 caatcgacag ttcaaccatt cagtatgaaa atgatgactt gatgcgggta caatggggta
     3781 ccgattatta tggcattgct tgctgtgttt ccgcacaacc aattgctgat ggaatccagt
     3841 acttcggtgc ccgggcaaac ttagccaaag cgattcttta tgccatcaat ggtggccgcg
     3901 acgaaattgc tggagatcaa gttggccctg cttacgaacc aattacttca gaatacatcg
     3961 attacgacga attcatgaag aaattagaca agcaaatgga ttggttagct gacacttacg
     4021 tgaactcact gaatgcaatt cattatatgc atgataagta ctactatgaa gctgcccaat
     4081 tagctttgaa gaatactgat cttgatcgga cctttgcaac tgggatttct ggcttatcac
     4141 atgccgcgga ttcaatctca gctatcaagt atggtcacgt taaagtaatt cgtgacgaac
     4201 gtggtatcgc cgttgacttc aaagccgaca atgactaccc acgttatggg aacaatgacg
     4261 atcgcgctga tgacattgct aaatggttag tcaaagaatt atacagcaag atgaacacgc
     4321 atcacctcta tcggaatgcc aaactttcaa cttctgtttt gacgattacc tccaacgttg
     4381 tttatggtaa gaacactggt accacaccaa atggccgtca aaaaggcgaa ccattctcac
     4441 caggtgctaa ccctgcatac ggtgctgaaa agagtggtgc attagcttca cttctttcaa
     4501 ctgccaaatt accataccgt tacgcaactg acgggatttc caacacgttc ggcgttaccc
     4561 ctaacacgtt aggccatgac ctcgaatcac ggaaagacac gttagtaaac atgttagacg
     4621 gttacatgaa gaacgatggg atgcacttga acatcaacgt cttcaataaa gacactttga
     4681 ttgatgctca gaaacaccct gaagaatacc caacattaac ggttcgggtt tctggctact
     4741 gtgtctactt cgcagattta accaaggaac aacaagatga cgttatttca cggacattct
     4801 tcgaatcaat gtaacattta atctttaata gttaagaagg cgaaaggctc atggaaaaca
     4861 aacaagtttc aacaacgcaa gcggcggcaa aagagccttt gataggctac gttcactcca
     4921 tcgaaacgtt tggctccgtt gacggaccag gtatccgtta cgtggcattc cttcaaggat
     4981 gccacatgcg ttgccaatac tgtcacaacc ctgatacttg gaaactcaac gttggcgatc
     5041 aaatgacggc cgacgagatt ctcgaagacg cggctaaata ccgggctttc tggggcaaga
     5101 cgggtggcat cacagtcagt ggtggtgaat cactggtaca aatcgacttc atcttagact
     5161 tattcgaaaa agccaaggcg atgaatatca gtacttgtct ggatacctct ggacagcctt
     5221 ttacccgaga acaacctttc tttgacaagt tcgaacgtct aatgaaggtc acggacattt
     5281 cgttggtcga cattaagcac atcgattctg ccaaacacaa gcagttgacc cagtatggga
     5341 acgaaaatat cttggatatg attcagtaca tggcccaaca ccacgatgat atgtggattc
     5401 gtcacgtcct ggttccccaa cggactgatt acgatgaaga cttgaagaaa ctcggcgatt
     5461 acattgctaa gattccaaac gacgtcgttc aaaaagtcga agtattgccg taccatactt
     5521 tgggcgttaa aaaatatcat gaaatgaaga tcaagtaccg gcttgaagga atcgagtctc
     5581 caacccaaga tcgggtggca aatgccgaaa agctactgca cactgctgat tacaacgggt
     5641 acaagacatg gatgccattg ccaaaacttt aaatcggcat ttctagcatg actaaaacac
     5701 cagcgttaca atcgtctacg gatggttgtg tcactggtgt ttttttgctg gctcgacgca
     5761 tgcacgtatt gctggccgga attagtacag tggcacgcaa aaaaggcgcc gcgagcaaac
     5821 cagcaacgtc tttccttaat catgccctat ccaatgaccg tcagcccttg gactggctgc
     5881 gaacaggccg gccactaact atgaatgcct agttccattc gagcttcgcg ggacatcata
     5941 ctttcgttcc aagcaggttc ccacacaatc tcaatctcga tattgttaac ttctggtaat
     6001 ttgatcagtt catcgtgaat gtccttagcc aaccattcgg tcaaaggaca gcccgcaatg
     6061 gtcaacgtca tggtaatttc agcggttcct tccgccgtca attgtgcatc atagatcaac
     6121 cctaagttaa ctagatcaat tcctaattca gggtcaatga catgtcctag cgcctcgaag
     6181 gcccggtctt taaacgttgt tgtcatcgta tctcgtcctt ccataccagc ttgaattcac
     6241 tgattaatca cgccaacgtt tcgcggtata agtgccacca cacttgatac acgtcatcgt
     6301 tatataaagc gctttcttgt ctacttctat tgtaccgtat gtcagcccat attcaatcaa
     6361 ttattagcgc taattagccg acttttcaaa cgatcggtca atcagcaaat catgcgacta
     6421 tttctcgaaa aaatttacta taatccccga tatagcagcg ttttgagtca ctattgattt
     6481 ttattgcgaa ttcgcggttg tttttgttgt aagcgtttgc ggtttatgct attatactaa
     6541 gtgaggaaag gaattaatcc tcgattagca aagcttctca aaagagtttg gctgtcgctg
     6601 taatgttaga cagctagtat cacagtttgg gtcgttatcg aaaccgtttt aagcgccgtg
     6661 aagcgttatc ggtctagcga gtgtcgtgag atttacgttg gatgactgaa cgttgaccct
     6721 tagataaacg ataaccgcaa agaattaatt ggcattagaa tgacgaacag attttaacta
     6781 agttttagtt ggaaacaggt gtctccgatg accagttgtt agttccacat taccagttcc
     6841 atttgtagac tcaggtatta caaagtttaa acggaggtgc atgtctgtta cgaagacatt
     6901 cccaagtttt aaacgcgagt ttgactttcg ttaaaacccg tctaacgagt cgcaatcaag
     6961 taacaacctt actttagatc gactatagca gatagttaca ataaatacgg gttagtccgt
     7021 tagaagttgg acacgcgtaa aattgaatag catgaaggtg tatcatatta acactgaaca
     7081 atttttcatt gctaatcagg attattcctc ataagtagaa ctcaagcaga gaagccttgg
     7141 gttctatttt tttgctctaa aatcagattt accaacagtc ggcaccagac gtaaccgttt
     7201 acatcctctt gcgaaaaccg tatactgaat ttaaatcaag ttgcacattg aggaggactt
     7261 tagttttgaa aacgattaat ttaggtcaca gcaatattca agcttccagc gtggcacttg
     7321 gcatcatgcg catggacgct ttggacgtcg cccaagccac caaggttatc gataccgctg
     7381 ctgatttagg catcaattac gttgattcag ctgatatcta cggtggtggt caatcatcga
     7441 ccatcttcgg tcaagcactc aagcaggctc acgtatcgcg tgatcagctc tatattcagt
     7501 caaaaggcgg cattgttcct ggcaagcgtt acgacttttc caaacagcac atactggcag
     7561 ccgtggatgg cgagcttcaa cgcttaggtg ttgattatct cgacaccttc ctcctccatc
     7621 gaccggacgc cctgatggaa cccgaagaag ttgctgccgc ttttgacaag ttgcaaacta
     7681 gcggcaaggt gcgccacttt ggcgtctcta acttcaatcc catgcaagtt gacatgcttc
     7741 aagcggcact aaaccaacgg ctcatcatca accaactcca atttggtatc atgcataccg
     7801 gtgcgatcga ctttggcttg cacacgaaca tgcaggacga acgtagtctt aaccacgacg
     7861 gcgagatgat cgaatactca cggctccata agatgacgat tcaagcttgg tcgccttatc
     7921 aatacggtaa cttcgcgggt atcttcttag acaatccgaa gtttccagaa cttaataatg
     7981 ccatgcaagc actcgccgat gagaaacagg tcactaaatc agctattgcg accgcatgga
     8041 ttctccggca cccagcccac ttccaagtca tccttggtac gatgaatccg gaacatctag
     8101 ctcaaaatgc tgctggagca gacgttacgc tttctcggca agaatggtac gacatttact
     8161 ttgcagctgg caacgattta ccttaatcac gatcgaccta acagaattga cgattagttt
     8221 ttacaatcaa aacgacgacc ccaaatcagg attgattttc aggtcgtcgt tttttagacg
     8281 tttcactaac atttttgatg tactcaccac atctacgcgt atacttaatc ttaccaagac
     8341 tcaggaggcg agcgaatgac atccacttgc acgatctgtg aacgaatcaa actaattcag
     8401 gcacatcaga atccttattt cgtttacgaa ctcacaacgg gctacgtggt ccttgctgat
     8461 agccagtact ttgaaggcta cacgctcttt ttagccaaac atcacgttac cgaattacat
     8521 catttaccgg cacacgagaa gttacgataa cttgaagaga tgagtatcgt ccaggaagct
     8581 tgtgcgcagg cctttcatgc agacaaaatg aacattgaac tactcgggaa tggtgatgcg
     8641 catgttcatt ggcacttatt tcctcgccat aacggtgata cgcccaaccc cggtcccgtc
     8701 tggtggacac cgctggaaac aatttatggt gatgatgtca gtctagacat tccccgttta
     8761 agccggttga agcgcacgct cagcgtagca attgaggcca cgcttaatgc tcgggaagca
     8821 gaattgcagg ctttagaggc actcacaagg cctgctagcc acagaattga cagcaattag
     8881 accaaatcag gacccagacc cgcttagatc ttggtggcta caccccaatt cttaatcgca
     8941 atccgtcacc gtatttcaaa ttgccaaaat ccacctattt atccggccga ctatcatacg
     9001 ctcgcttaga tttatagcca gctcgaaaaa ccgtcttcat aacttcaatg tgccgttcct
     9061 tagttgcttg tgccttagtt ccaaaaataa agcgggccca ttcgcgctga taaccaggtg
     9121 tcaaagccac aaagaacgtt tgcaattcag catcaaccgc taacaattcg gttaccgccg
     9181 gaatattttt ttcaaatgaa ctgaggggtg ctgtactcat aatcaaacct ccgattagtt
     9241 ttacttaaat ttactgtaag aaagggaaaa tccctaattt tcaggttttt atatttcgaa
     9301 ttttcataaa attgcgctat cattatagta taagtattat tatttgacta ctataattaa
     9361 ccatactgct attcaccaag gggagccctg ctatgccaaa atttgatatc accctcatca
     9421 gtcccgaacg cgctaaagcg atgttgactg aatataaaga acaacgtaag aactctgtcc
     9481 cacatctggc ccatcctggc cgctatatct tgccggatta caaattaact cgtcgccggg
     9541 ccgcattcaa aattgttaaa catacctttt taacgcccca ctacaagtct tacgttgcca
     9601 tggactctga caacggccac acactctggt ttcataattt cggttcccta accgaagctt
     9661 tattctggtt agaaaccggc cttaaaatca gcgataccga ctcccattct aactacaagg
     9721 aatggatggc taagcacact acggaaatcg aaaccttcaa agacttgctg cgcgagcaga
     9781 agcataaaca agggcccaag actaagaaaa aagccaagta gcccgttttg acacctagat
     9841 tcagataagc agcagtacgc tcattagcgt gctgctgctt ttatttacga tcaactgtgc
     9901 cattcattac tgactagacc aacctaaaag tggctatcca aaaacgactg cagcttgcgt
     9961 gcaatcacgc gatgaccggc attgttcgga tgcaaagtat ccaccgaata aatggccgct
    10021 tgagcgggaa tcgcaaatgt cattcccgca tcacggtaca agctcaaatg tgggacgcca
    10081 tagtctgcag tcatctgggc aatcgctgct tcataatctg actgacgata cccgagacca
    10141 ttagtcaccg cactaaaact gcccccaaaa tcagagccaa tatgaattgc tgaaataaat
    10201 aacttcggca cggtcggcca attcgtctgt aatcccgtca gtaacatcat taacgcgcca
    10261 taaaatgtcg tcatatcgca atcaccgtat tgccctaacg gctgatcccg accatagtca
    10321 ttgacgcccc caaagacagc aataaaatca gcatcttcag gaatagcttg atagcgcatc
    10381 gccatcgcat cgtagcgact cccaatcgtt gaaccagaga ttcccaaatt atcgctccgc
    10441 tcgacatccc aatcagccgc caaaatatca tgataatgca ccgtcgccaa cccattattc
    10501 gccgtaatcg aatctcccaa ccacgccggc cgcttaaaac taacatgccc attactaatc
    10561 gccatagcca atcctccctt tactatcatc gctatcattc taatccatcc cacctgaatt
    10621 atggtagaaa gatgcctttt agggttggtt ttctgttcgt cagccggtga gcgtcctatt
    10681 ccgacctccg gggctgggtg acaattgctg gaacgcagcc gacatcgatt tgagctaacg
    10741 cataacccgc gtcatctcaa atacgagtct tattctaagc cggaaggaaa tcacttccga
    10801 ctaagaataa tttggctact gagcattgtc acccagcccc tccagtctca agccacgggt
    10861 tgaagccgag cattgtctag ccaacggatt aatgcggttt gggcatttgt ccgttggcat
    10921 agcaagcaca gactttagtg gcaccgaaca cgtttcggta agccgctcga atggctgatg
    10981 aacggccact taactcggca caattggtcg ttggctattt tgataccgga actttaaacg
    11041 agacgttagg gttaccctaa ccactttgtt gaggtgttct attattacta tagtaattcc
    11101 gaaatagcga gctatcccaa tatcttttcg acctaacagt tgattaataa aattactgtt
    11161 tatggagaac aatgacaaat tcatcaaaag ttgggtatat cttcgtccac cattcgaata
    11221 ctgtcccgaa tggaaggcgt ttcggccaat gctcagcggt gaaattccac ttagcaagcg
    11281 tccttggctt ggttagtaga agaccagtat ttaagacgtg gtcttcgact taaatctgtg
    11341 tccaccgcgt tccagcaatt ggcagaaatg cctggagagc ggcgtaggac gaacgaacta
    11401 agcaggttta cgctaaccgg aactgtttcc agcgggccta agctggtggc tgttgacttt
    11461 aaataaaggc atctttctac cattatttca aacaggtggg ccaatcttaa aaggctcgta
    11521 ttatggaaat ccataatacg agcctagttt aattgatata tttagttcaa ctgagtagcg
    11581 ctaatcggct tccgtttcac gtttccgtgc agtacgccgt tcgcgtgcgt agtcagtttt
    11641 agttgtgatt tcaacgtcac gtgctagccg tttccggcgt gctaattcag ctgctttggc
    11701 attggctttc gcagcttcct tgactggatc agtcgttaag tcgtgatgga tcgagtacag
    11761 taagacgagc gcgacaatcg ttaatgggaa gccagacatc gcacagatgg actgaatcga
    11821 ttcaaagcca ccgaccgtga caagccccaa tgagaagact aggaagataa cgacccagct
    11881 catccgattg aaacgacttg gttgttcccc cgcggccaac tttttactag taaatgacga
    11941 ggtaatgaag gcaaatgaag ataccgtcgt tgctaagaaa ataaagcaag ataggcagta
    12001 caaagccagc ataatcatct tcaatggtaa ggtcgacaat actgctgcaa tcacagcggc
    12061 ttgtccttgc gtatttaaga tatgaactaa gttaacgatg cccatccgtt gcaagtataa
    12121 ggcataacca cccaagatgg cgtagaaact gacacaacct aatgagcccc atagcaacat
    12181 accaccgagt acctgacgaa tcgtccggcc ccgagaaatc cgggcaatga ataagcccat
    12241 gactggcata aaggataacc accagcccca gtagaagatc gtctgccgtt gcatggccgt
    12301 tgcgtgacca tttggtgcag tattcgtgct caacgtaata aacttattga caaacaagcc
    12361 aatactatta gtttctgagt ttaaaatata caaagttggg ccaacaatta aaacaacgat
    12421 taagaagcca atcgctaacc aaacatgggc agcacttagt cgaccgatcc ccttcttcaa
    12481 gccattgaaa acagccatgg cgaagattac gaataataag gcaaataacc ctaactttaa
    12541 agtcatcgta tcggcaatcc cggtaacggc actcaaaact tttgaaatga cagggatttc
    12601 catcccgact gaagtaccaa caccacccat aatcccaata ataacgagaa aatcaatcgt
    12661 gttccgggca atttgcttac ccttaccagg accttgtagt actgaaattg cggcactgag
    12721 ccgctgaacc ttgatgtgtt taacatacat tgcataggca attgcaatcg tggctggcgc
    12781 aaacatcatc cacgccattg gtccccaatt aaattgtccc agcatgtgcg cataattata
    12841 tgcagaagtt gaaaacggct tgacgccgaa tgaagggctt tggaggtacc gtaacgggtc
    12901 aaccatgctc aacattaaaa tgctggcatc gatcccggtc gcgtaaacca tactgcccca
    12961 gtgatacgtt gaaaattctg gtttgtcatc aggatcacca agtttggttt tccctaactt
    13021 actaaaccct aagtaaatga aaaagataaa agtgatcaca tataccgaca tataaagcca
    13081 gctcatgtta tttgtgagcc agttcaagat gccacttaaa ctcgtctcca gcgaatggcc
    13141 ccccattaat aaaacaacgg aagccgccgc aaagagccca attgttggta aatagaccca
    13201 ccaatcaata ttcttacttt ttaaaataat aaacctgcta ctgagcatat actctctata
    13261 tttagatcaa attcgtggtt cttcctacca gcaatggtag tccccacgcg taaatttccg
    13321 actagcaatc ggtacacccc tccgagttaa tcctcggagc actcagcacc ctgactgtat
    13381 caggtttgac cggcattgtc atccgcattc tgtttgtgct aactcaaaat cagtagcaga
    13441 atttccttct ttccgttggt tgaatccgga caacgccata ctgacaaatg atttttaatt
    13501 gcttaatcga cgttggtgtt catcttgttt agctagtgtt tctattacca tcgtgccttt
    13561 agcacacgac cgtcgtcaca ccacgtaacg attaatggtt acactgctct tgctaataga
    13621 taaccccctt gaatcaccag ataagcccac cgcacaactg ttagattaat tgcttggtgc
    13681 accaaaaaag cgcttagtac cgggtaacaa gttaccacct gcacagcgca cgttggctta
    13741 tacaaatgct gatttcagta ttttctgata tctgatgttc gtttataagt atactagtat
    13801 taaatcagaa gtaaaatcaa ccattttgag ccgtcgaggc ctaacccgtc aaggattaga
    13861 cgagttttac acccatattt tttctgaaac tttttaaaag ttttcgtaat aattagtttt
    13921 tagtttagaa tcattcttat ctgtttcaat taaaccgatt tcatgttatt cttgtaacaa
    13981 gttaaaaaac gttatcatct aaaaggaggg gaactgcatg cggcactact ataaattaat
    14041 tttaacggtc agcgtcggta tcattgcggt tgttttacag tttggtttgc actaccaatt
    14101 ggcagcacaa atcatcatta cattaatggg gtcacttatg gccttatcaa tgttagttga
    14161 gatgatcaaa accttacgtt caggtaagta cggggttgat ttattagcaa ttacggcgat
    14221 tgtggcaaca ctagctgtcg gcgaatattg ggctagcctt gtcgttctaa ttatgctcac
    14281 tgggggtgac tcgttagaag attatgcggc caaacgagcg aataccgaat tgaaagcctt
    14341 gctcgataat tcaccacgta ttgcccaccg ctcagtcgcc ggccaattaa cagatattgc
    14401 cgttgaagat gtccaaattg gtgatcagct agtcgtcaaa cctggtgagc tagttccagt
    14461 agacggtcac cttattcaag gaacggcact ctttgatgaa tcttcattga cgggtgaatc
    14521 taaaccagtc gacaagcacg ttggcgatga cattatgtct ggtgcggtca acggcgatag
    14581 tgccgttaca atggttgttg ataaattagc cattgatagt caataccaac agttagtcaa
    14641 attggttaaa gaatccgaat cacgaccagc caaattcgta cggctggccg atcgctatgc
    14701 agtcccattc accctggtag catacgtcat tgccggagta gcttgggcat tcagcgggga
    14761 tccccaccga tttgcagaag tcctcgtagt ggcttcccct tgcccgctga ttctcgccgc
    14821 acccgttgca ctcgtctcag ggatgagccg aactagtcgg aacggaatcg tggtcaagac
    14881 tgggaacatg ttggagaagt tatctacggc taagtccgcc gcgtttgata agacggggac
    14941 cattaccagt ggtcaattaa cagtcaacca aattgttcct cagtctggtt ttactgccga
    15001 acaaatcttg cacctcgcag cgagcgctga acaaaactca agtcatatcc tggcccgctc
    15061 actcgtcaag tatgcgagtg ccactagcct cagcccggca acacaattag cagaagtaac
    15121 gggtaatggg gtcacggcaa cgattgagca gcaacaggtc aaagtgggca aacttaaatt
    15181 cgtcgcaccg actacaaccg ccaagccact tgctaccact gctatctacg tcggcatcga
    15241 tgaccagtac gcgggttaca tcacgtttat tgacaatgtc cgccccgaag cagccgccac
    15301 gcttaaagca ctccacgctg agggcgttca aaacgtcatg atgcttactg gcgaccaaca
    15361 ggcaattgct gatcatattg ccgccgatgt cggtatcgat accgttgctg ccgacctcct
    15421 acccgcagat aagattgccc acttaaaggc tgtaccagcg gccgaacgcc ccgttatcat
    15481 ggttggtgat ggtgttaatg acgcgccttc cttggctgtt gctgacgtcg gcattgccat
    15541 gggcgcccat ggctcaactg ctgctagtga atcggccgac gtcgtcatct taaaagacga
    15601 tctcagtcgc gtggtcacgg cggtgcgcat tgctaaagat accatgcaag tggctaaaca
    15661 agccgtttgg at
//
