LOCUS       c00084_gnlPro..        12349 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GEMNEGCL_101.
ACCESSION   c00084_gnlPro..
VERSION     c00084_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 03:59:38
            Original ID  :: gnl|Prokka|GEMNEGCL_101
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12349
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12349
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5869:8404]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5870..8404
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..12349
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12349
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(3..74)
                     /locus_tag="ctg84_1"
                     /transl_table=11
                     /translation="MSLKELFKSNVFRGNCQIFCVNRF"
     CDS             complement(248..1288)
                     /locus_tag="ctg84_2"
                     /transl_table=11
                     /translation="MPGIVEQTLLEQQNIDLNEMVTMNQMIDQLLPNASKELQQKLKIK
                     IYNFVRTRKQPSITVRRRKYFKPAVAKLIIGNVQDYADAIERRAKEAPAKEDATDKRPA
                     SKSKRVKTITKRKILAKVIKNDKIDKSIQKKLEDKIASIVKTNFIKPVNKRGSFSVEDG
                     EKVIAELSPFYQNIKIDQKYRKNAEKAAENKETETKEKPEQHSKDQNESREGQSKDFER
                     KNNQKNSNNRNNNNQTQNQRKRQNKHPFEIRRENNNRSRNNQSNRRYNNRNNYDNRNNY
                     EFDEASGLRERYNTVIRNYNQLEQRYNALQDKYNQALDDKARLIEEMGKKNEDLRRVLI
                     DVLRKM"
     CDS             1632..1760
                     /locus_tag="ctg84_3"
                     /transl_table=11
                     /translation="MKGMRTLIKLLLIGGSFLTLGLMAISSVLINKPAVAKVKHRH"
     CDS             complement(1858..2550)
                     /locus_tag="ctg84_4"
                     /transl_table=11
                     /translation="MTKLILGGEVMKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTS
                     QENEPGTLFMQTSHDEETTNFVVECYQDEASYDTHANSKQFKDFTDVAKDILTSRVKVE
                     LFPEFISTKAEKLAVTGSNDYVIYLTEIGVSLGKGDEFAHAVMKEMKTAVEEEKDILAM
                     IAGTVADQPNEWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKLQPDVIVD
                     QGAIFYQP"
     CDS             complement(2616..3122)
                     /locus_tag="ctg84_5"
                     /transl_table=11
                     /translation="MVLVLGLTGLASQVETVDASTYGNGVQVTIPKKMQGTWYSYDRNA
                     HNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWMSGKTTKMKNDT
                     FYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKLAKKMKDYKFKK
                     VNYTL"
     CDS             complement(3088..3198)
                     /locus_tag="ctg84_6"
                     /transl_table=11
                     /translation="MKADSYILHSGDDFYAKKNFVTFNINGTCFRINWFG"
     CDS             complement(3254..3859)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg84_7"
                     /sec_met_domain="LysR_substrate (E-value: 1.6e-12,
                     bitscore: 37.3, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHDGAFA
                     KLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDMTCFI
                     VAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAALLVASRSGYFILNENTARLINTTDL
                     QPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             complement(3861..4022)
                     /locus_tag="ctg84_8"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             complement(4038..5240)
                     /locus_tag="ctg84_9"
                     /transl_table=11
                     /translation="MNKFIDVRIGISMELKKNKNNLKQITALIQYAFLKNNDLTKDENF
                     MSRYDHSTGYGYFDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASYPEYRGQGHISQL
                     MKEILHDLHRQDIPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIV
                     RGKWDNLAVQNGVIQLYERQLHTDDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERP
                     ISYLIYRIRDNTFLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPE
                     QNELQVDLRPYMMSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRK
                     VAVERKEDALVDFSGSITAWTQVLLGRLTMNAAVKLGLITDYRIKKLDFVKGDVSFYDY
                     F"
     CDS             complement(5320..5856)
                     /locus_tag="ctg84_10"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDINMNI
                     PGPIKNNRYLTKMFMLGINELENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFENQISLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPAKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             complement(5870..6772)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_11"
                     /sec_met_domain="OTCace (E-value: 5.2e-47, bitscore: 149.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 2.5e-20, bitscore:
                     63.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGDGRDNVADSLLVCGSMLGVNVHIVTPKPLFTHPDVQKIAQNFA
                     QDSGSKNLITDDIAQGVKGANVVYTDVWVSMGENDWSERIKLLKPYTVTMKMMQMTGTP
                     DDQLIFMHCLTAFHDRTTQVGEEIYEKYGLNEMEVTDEVFNSKYAWQFTEAENRLHSIK
                     AVMAATLGNLFIPIACGGGGILVIVKDGHLRGVAGVIHKDFSAAKMAEDINADELVILT
                     TVDHAFLNYGKENQQAIGKIKVEQLKQYLAAGYFAAGSMKPKIEAAIEFVEKTGNLAII
                     TSLSNANKLADGVGTIIYN"
     CDS             complement(6733..7164)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_12"
                     /sec_met_domain="OTCace_N (E-value: 5.2e-38, bitscore:
                     120.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWKWVMAAIMLPTVF"
     CDS             complement(7175..8404)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_13"
                     /sec_met_domain="Amidinotransf (E-value: 2.4e-109,
                     bitscore: 355.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQ
                     LLLNYLQELLTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQ
                     QAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELV
                     LNNHVLAVGISQRTSATAITDLAHNLFDHSSYDTILAIKIPHNHAMMHLDTVFTMINYN
                     QFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDP
                     IAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRC
                     MSCPLIREDL"
     CDS             complement(8478..9326)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     75.6; E-value: 7.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg84_14"
                     /sec_met_domain="LysR_substrate (E-value: 1.7e-29,
                     bitscore: 92.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2e-24, bitscore: 75.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDVGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQPKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIAA
                     I"
     CDS             9455..11755
                     /locus_tag="ctg84_15"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNVKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGKVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNRYIITINFIN"
     CDS             complement(11796..12110)
                     /locus_tag="ctg84_16"
                     /transl_table=11
                     /translation="MKRCKNWVVTIVAFLMLVGEISVLPANLQGSTSVVNAAIHHRRRK
                     HQYRDKTKIYTSNYRIVDNKRSKIFHVMRGHNYRMNRENAVFFKSKAAARAAGYRESKR
                     "
ORIGIN
        1 aaaaatctat ttacacaaaa gatttgacag tttcctcgaa acacattgct tttaaatagc
       61 tcttttaaac tcatacttct cctccattaa tcattaataa aaatatttat catcctttaa
      121 tcttactaca caaaaataat tttttacaca tattttttta atttttaagc taaatcatat
      181 ttcataaaca taaaataaga ctagtaatca attcaaattg actactagtc tctttgttta
      241 ccaaaaacta catttttcgc aaaacgtcga tcaatacacg acgtaagtct tcgttcttct
      301 tacccatttc ttcgatcaat ctagctttat catctaaagc ctgattatat ttatcttgca
      361 aagcattata tctttgctcc agttgattgt aatttctgat tactgtattg tagcgttcac
      421 gcaaaccgct agcttcatca aattcataat tattccgatt atcataatta tttcgattat
      481 tatagcggcg gttagactga ttattacgtg agcggttatt attttctctt ctgatctcaa
      541 aaggatgctt attttgtcgc ttacgttgat tttgcgtttg attattatta tttcgattat
      601 tgctattctt ctgattattc ttacgctcaa agtccttaga ttgaccttca cgactttcat
      661 tctgatcctt agaatgttgc tcaggctttt ctttagtttc tgtttcctta ttttcagccg
      721 ctttttcagc attcttgcga tacttttgat caatcttgat attttgataa aaaggactaa
      781 gttcagctat aactttttca ccatcttcaa ccgaaaaact tccccgcttg ttaactggct
      841 taataaagtt ggtcttcaca attgaagcaa tcttatcctc taatttcttt tgaatagatt
      901 tatcaatctt atcattcttt ataactttag ctaaaatctt acgcttagta attgtcttaa
      961 cccgcttaga tttagaagct ggcctcttat cagtagcatc ctctttagct ggggcttcct
     1021 tagcacgacg ttcaattgca tctgcgtaat cttgtacatt accaataatt aatttagcaa
     1081 cagccggctt aaaatatttt cttcttcgca cagtaatact tggttgttta cgtgtacgca
     1141 caaagttata aattttaatc tttagttttt gttgtaattc tttacttgca ttaggcaaca
     1201 attgatcaat catttgattc attgttacca tttcatttaa atcaatattt tgttgttcta
     1261 ataatgtttg ctctactatt cctggcattt ccaatcctat attcttttaa ttttttcaca
     1321 acaaaaaggg ccattacggc ctattttgca ataatacatc aattttctca ttaataaact
     1381 taatgcactt tccattttac aacattaacg ctatttacga aaagggctac aagcatattc
     1441 tctatttttt aaccaaaaca agcagcatcc catcgatact gctttatttt atgcgcagtt
     1501 gcactagact ttgactctat ttctatttta cgtgctaacc agcctttttt ctagttttat
     1561 tttcttaact aatccattag gttttacata taaattctta atattatttc gctattataa
     1621 gatcaattaa gatgaaagga atgagaacct tgattaaact actcttaatt ggtggatcat
     1681 ttttaacgct tggtttaatg gccatcagct cagtattaat taataaacca gcagtagcaa
     1741 aggtaaaaca tcgccactaa aaaccagaat aatatatgtt aataaatctt ttcccctcta
     1801 actagaaaga ccaggttatg tactccacat agcctggtct tcttttcgtc ttattcttta
     1861 tggttggtag aaaattgcac cttggtcaac aattacatct ggttgcaact tacgtaaact
     1921 cttactttca acacaatatt ttgtattatt caaatactct ttgaagttct tagtttccaa
     1981 gtgctgcttg taagcttcat tattacgata aacttcaata gctaaccatt catttggttg
     2041 atcggcaaca gttcctgcaa tcattgccaa aatatctttt tcttcttcga ctgccgtttt
     2101 catttctttc attacagcat gagcaaactc atcgccctta cctaaagaaa caccaatttc
     2161 agtcagataa ataacataat catttgatcc ggtaactgct agtttttctg cctttgtaga
     2221 aataaattcc ggaaacaatt ctacctttac tcgactagtt aaaatatctt tagcaacgtc
     2281 agtaaaatcc ttaaattgct ttgaattagc atgagtatca taacttgctt cgtcttgata
     2341 gcattctact acaaaattag tagtttcttc gtcatgactt gtctgcataa acaatgtgcc
     2401 tggttcgttt tcttgagaag taagcatatt atgttgccct gccttaacga actttgcatg
     2461 atcctcttta ttagtttcta gtttatataa acgcaaaatt ggtgtttgtt ttaatttcat
     2521 aacttctcct ccaagaatta attttgtcat tattatacta aattttatcg cgtctattag
     2581 taaaaaacat cccttagtta agggatgtca caaaactata acgtgtaatt aactttctta
     2641 aacttgtagt ccttcatttt tttagctaat ttcttgcttc tgaagtagtt accaccatca
     2701 tatctactag aataaaccag cacgttatgc tttttaccat taatggtttg tggtaccact
     2761 cgataaagac tccaattttc aaaagtaatc cacggatcaa tctcatagaa tgtatcattc
     2821 ttcattttgg tagttttacc agacatccag ttttgcgtta ccttatcaaa gttcttctgg
     2881 ttagcaattc taccattgaa gtaatcacta attgtcgaag cctcctgggt aaatattggt
     2941 ttgccattaa cagtatgttc agtaaaggtg atctttgtgc cattatgtgc attacgatca
     3001 taagagtacc aagtaccctg catctttttt ggaatagtaa cctgtacacc attaccataa
     3061 gttgaagcat caacagtctc aacttgacta gccaaaccag ttaatcctaa aacaagtacc
     3121 attgatgtta aaggtaacaa agttcttttt agcataaaaa tcatctccag aatgtaaaat
     3181 atatgagtcc gctttcataa tatattttac agtatcttat agtacttaga caagatattt
     3241 ttaactttac agattaatat tcttgctgca atagctttat aaactcacta cttaacgctg
     3301 aatttgactt ataaaaagcc attatctttt gctttattaa ctgaccatga tcaagcaaga
     3361 aaagtggctg caaatctgta gtattaatta acctagccgt attctcattt aaaataaaat
     3421 agccagacct agaggcgacc aacagtgctg cttcttcgac cgagttagaa gcgatgaatt
     3481 gactgccaat ttgatacaaa tctttaaata aatgtagctc actaacctct tcttcaggtt
     3541 tagccacaat aaaacaagtc atatcattga gctcgtcttt ttcaatcatt tgaatgccat
     3601 taggatacat tcccttgggc aaaattgcca ttacaccagc ttgagtcaat tctgtttcat
     3661 caaagttaag attctcgtca cgcaaatcat tgattgctat gtctgcttca tcttcattca
     3721 gttttgcaaa agcaccatca tgactagtcg caagtagttt tacatctaca ttaggatgtt
     3781 ttaacacaaa atgctgcact gcctgatcta attccttacg acctaattgg tcaaaatatg
     3841 caatctttaa ttccgtcatt ttatttttca tccagcggtg cgtgtccttc ttctgctact
     3901 cttcttttat ccttagtatc ttcatgctta ttaagtgcca tcaaggcaaa aaagatcaaa
     3961 ttcaaaccac taactacaat gccaaataat tttattaaat tgagtttctt ttctttactc
     4021 attttttaac ctcacaacta aaaataatca taaaatgata catcgccttt aacgaaatct
     4081 aattttttga tgcggtaatc tgtaattaat cctagtttaa cagcagcatt catggttagt
     4141 ctacctaata gcacctgggt ccacgcggta attgatcccg aaaaatcaac caatgcatct
     4201 tccttacgtt ctaccgctac cttacgtcca tgattactta attgccaaac tccaatattc
     4261 caaggacact gttcatcgct attgacttcc agattaaaat caccttcttg cattggccgc
     4321 atacaagcca aaactttttc aaaatcaata attcgactca tcatataagg acgcaaatca
     4381 acttggagtt cgttttgttc aggaaaaagt tcagctcgta acgatttctc tggtacgctc
     4441 attttaaatt gcttaacact gcccgcgtgc gaacccataa aaccaaacat actcagtaat
     4501 ccctgcggcg taattgcgta catttcatca gctaaaaaag tattgtctct aatgcgataa
     4561 atcaagtaac taattggccg ctcatccgcg tcaaaataaa cggctacatt gcggtgatga
     4621 taataagaat caagtctatt ccaccaccat gcctcacgta caaccgtgtt acgttcatca
     4681 tcagtatgca gttgacgttc ataaagttga atcacaccat tttgaacagc taaattgtcc
     4741 cacttgccac gcactatatg accagaacgt ggtaatttaa aactacgcaa tgcgcttcca
     4801 tcaaagcgat attctttttg ataaatacta ttgctaaacc cgtactggcg ataaaagctc
     4861 tccgaaaatg gtgccaggtt agcaaacgga atatcttgcc tatgtaagtc atgcaaaatt
     4921 tctttcatta attgggaaat atgaccttgg ccacgatact caggatatga agctacataa
     4981 cctattccag ccatcggtaa atgatgccca aaaacatcac ttttaaatcg attaaccata
     5041 atatagctag ctaatttttc cttatcaaaa tagccataac ctgtactatg atcataacga
     5101 ctcataaaat tttcgtcttt agtcaaatca ttatttttca aaaatgcata ttgaattaat
     5161 gccgtaattt gctttaaatt attcttattt ttctttaatt ccatgcttat tcctatacgt
     5221 acatctataa atttattcat tactatttta gttcattttt taaattttta actagatttt
     5281 tcataaaaat aaaccggaat cataaaatcc cggtttattt tacgcaacgt attcttgata
     5341 aagctgagag ataaatgcct gcatctgttc cactgaatgt ctccggctgc gagcacattc
     5401 tttagcaggg cgatcacata aaaagcactt acgtggctgc ctgcccaaat ctctgcgtga
     5461 aattgcagct tgtttatttt ttaccaacac gtctgcatca aagagacgtc ccaatgatat
     5521 ctgattctca aaatcaattg ttgagcgctt tactttttca attgacaaag ataatacata
     5581 aaagttttca cagccactat catcattaag ctgtgtcacc aatttaaaat gataacctag
     5641 gttagtccaa gcattttcca gctcattgat acccaacata aacattttag ttaaatagcg
     5701 attattcttg attggtcctg ggatattcat attaatgtcg actagagttt gattaggata
     5761 cttattaaaa atcttatgtt gtacagctac tcgcctatct ttagctgcta aaacttgggc
     5821 aatatcctgc ttttttcctt cattaaaaat attcattttt atcacccagt taattataaa
     5881 tgattgtgcc gactccgtct gctagtttgt tggcattgct caaagaggtg ataattgcta
     5941 aattacctgt tttttctaca aattcaattg cagcttctat cttaggcttc atactcccag
     6001 ctgcgaaata acctgctgct agatattgtt tgagctgttc aacttttatt ttaccaattg
     6061 cttgttgatt ttctttgcca taattcaaaa atgcatgatc caccgttgtt agaattacta
     6121 attcatcagc gttgatatct tctgccattt tagcagcgga aaaatcttta tgaattacgc
     6181 cggcaacacc tctgagatgc ccatctttca caataacaag gatgccacca ccgccacagg
     6241 caatcggaat aaataaattt cctaaagtag ccgccatcac tgctttaatt gaatgcaatc
     6301 gattttcagc ttctgtaaat tgccaagcat actttgaatt aaagacctca tcagttactt
     6361 ccatctcatt taagccatat ttttcataga tttcttctcc cacctgagtt gttcgatcat
     6421 gaaaagctgt caaacaatgc ataaagatca attggtcatc tggtgtacca gtcatttgca
     6481 tcattttcat tgtgaccgta tatggcttta ataatttaat tcgttcagac caatcatttt
     6541 cacccatcga aacccaaaca tcggtataaa caacattggc tcctttaacg ccttgagcaa
     6601 tatcatctgt gatcaaattt tttgaacctg aatcttgggc aaaattttga gcaatttttt
     6661 gtacatcagg atgtgtaaac aaaggcttgg gtgtaacaat atgtacatta acacctaaca
     6721 ttgagccaca aactaaaaga ctgtcggcaa cattatcgcg gccatcaccc acttccaaac
     6781 aggaacgcca gaatatttag ccagctcttc tacatcttct tgagcaaaac cgcgatattc
     6841 aattccatca tacattgagc ctaggacttt agccgtatcc ttgacgcttt cttttttacc
     6901 taagtggatc tcgcttgcgc ctagatattc tggatgagca cctaaatcat tacaagctac
     6961 tacaaaagca gatcgcgtcc tagttgaggc tttttcaaaa agtagtgcaa tatttttacc
     7021 tttcagatat tcatgtggga tatgctcttt tttaagttct tttaaatgta atgcaaaatc
     7081 aattaaatat gaaatttcag ctggagtata gtctttacaa tcgagaaaac ttctaccttg
     7141 aaaaacattt tgtaaatatt tcattttttg cctcttataa atcttcacga atcaacggac
     7201 acgacataca tctaggaccg ccacgaccac gtgagagttc actagaccga atctcatgaa
     7261 cgatgatgcc atgttttctt agcaaatcat tggatacata attacgatca taagtaacga
     7321 cttcacctgg tgcaattgcc aaggtatttg agccgtcatt ccattgttca cgtggtgcgg
     7381 caattggatc accaccacca gttggaatta aatccaattc gcttaaatgt aagttttctt
     7441 tcaaaacctg caccaaatca ttcttttctg tgatttttac accgttgtga tcatcgggct
     7501 gtagaacata aatatcaatt ttgccggctt tatctaaaat aaagggatga accgtaaatt
     7561 gattataatt aatcattgta aaaactgtat caaggtgcat catagcatga ttgtgcggaa
     7621 tcttaatcgc taaaatcgta tcataacttg aatgatcaaa taaattatga gctaagtcag
     7681 taattgcagt tgcagaagtg cgttgtgaaa tacctacagc taacacatgg ttatttagaa
     7741 ctagttcatc cccgccctca aggcgaccat gatgataacg gtcacgccaa actggaatag
     7801 ttgcgttctt gaaatcagga tgatttttca aaattgtttc cataaataat gattcacgtc
     7861 gtctagctct gaaagtcatc cggttaatgg tcatccctga accaattgca gcctgttgat
     7921 ctcgagtaaa atatacattt ggcattggat caagataaaa agggtaatct gggtcctcag
     7981 ccaaatctgc taaagatggg gtagaattat gaatcgcact ttttctaatt ccagcaatca
     8041 ccgtttttac catttcctta gttagcaatt cttggagata gttcagcaat aattgatgca
     8101 aaggatcctg ttttttaata cttgattcat ccagtaactg atctaagaat gcccgacgaa
     8161 ctttctcatc tgttaaagat tctgctaata aatcctcaag atataatact ttgatcccct
     8221 gctgcctcaa tacatgcgca aaagcatcat gttcttcttg ggcaatcttc agataaggaa
     8281 tatcgtcaat caacattcga tgcaaaatat ctggggctag attttctagt tcttttcccg
     8341 gtcgatgtaa catcaccgtt tttaacttac caatttctga ataaacatga atcggactcg
     8401 acattcaacc accttctatt aattattgta cccgtttaca tttattatgg atcaattagg
     8461 taaaagttac agtattatca tattgcagca atgatttttt tcattaaagg tgtaacttga
     8521 tgatctttac gccaaaccag ctgcaaatgt gttatccaat tagcatgttt aattgcgatc
     8581 atattttctt gggcataagt tgtcgcaatt gattctggta ctagcgctac tcccattttt
     8641 ctcttggccc aagtaattgc tgtccgtgaa tcatcacact taaccgcata aaatggttta
     8701 agcccatgat gtgcaaaagt ttgattaaaa atatcctcaa agcgacgata aataatcaat
     8761 ggctgatctg ctagatcttt aatgcgtaat tctttttttg gctgaaaatc tgggtctaca
     8821 ctaatagcca tcattttttc agttgttaaa gtcttagtat ttaaacctgt ctggttgtaa
     8881 ggcgttcgta caatgcctag atcgattgtc tttttttcta atttatccag gatgccataa
     8941 gtattatctt cataaatatc aaaagaaatt tccggataat attttcgtaa ttcattaaaa
     9001 gaattcattg gtatcaagcc cgttgaggaa gatgccattc caattgcaat cgttcccaat
     9061 tcaccggaaa tagtcttatg tacttggttt tcagcatttt gagctagaga aataatttca
     9121 ttggcatagc tttgaaaaat ttgtcccaca tcagttagct caataccatg tgccgttctt
     9181 ttaaataatt gcgcgcccaa ctctttctct aattgtttta attgatagct taatggtggc
     9241 tgtgcaatat acaagcgctt agcagctgct gtaatctgct tttcttctgc tacaactaga
     9301 aaataacgta actgttttag attcatatta tttatccttt ttttatttca attgatagtg
     9361 atattaaaat atttaatatc ttatattgta ttttagtatt ttattcatag caatatctgt
     9421 gctaccttat taaggtagat ttggagggaa aataatgtct gataaatttc acggcttaac
     9481 tcaagccgaa gcagacaagc gcttaaaaga agatggctta aatgaagtac cagagcctga
     9541 atacaatttc tttaaagagt tcttgtctaa gttatggaac ctatccgctt ggattctaga
     9601 agctgcttta attctagaat gtatcttggg caaatgggtc caatcattat tcgtgttgtt
     9661 gatgctttta tttgctgcat ttaacggtgc atctaagaaa aagcaatcaa gacgagtttt
     9721 aaataatatt tcacacaagt tgactcctac tgtatcagtt gaacgcgatg gcaagtggat
     9781 caaacttgat tctaaacaac tagttaaagg cgatttaatc tcacttaaac gcggggacgt
     9841 actcgcagca gatgttaaaa ttgttgacgg taacttagct tgtgatgaaa gctcaattac
     9901 aggtgaatct aaaccagtta agaaagcaat tgatgacacc gcctttgccg gtactacagt
     9961 tgttgaaggt gatggcctag ctgttgttac tgctacaggt aaagattcta gaagcggtaa
    10021 gacgattaat ttgatcaaca attccgctgc tcctggtcac ttacaacaac ttttgactaa
    10081 gattatctac tacctttgct tactagatgg tgttttaacc ttagttatta ttatcgcctc
    10141 cttcttcaaa ggcggtaatt tcaatacctt tattaatatg ttgccattcc tggcaatgat
    10201 gtttattgct tcaattcctg tagcaatgcc atcaactttt gctttatcca actcatttga
    10261 agcaacccgc ttaagtaaag aaggagtcct gacttctgac ctaactggaa ttcaggacgc
    10321 agctaacttg aacttgcttt tacttgataa gactggaaca attacggaaa acaaaactgc
    10381 cgtagccgct tggactgatc taagtgactt gcctgacaaa gacgtgcttg ctttagctgg
    10441 agccgcaact gataaacgta atgctggtat tatcgataca gcaatcgatg aatacttagt
    10501 agaaaataac attccagtca tgaatgctga aaactttact ccatttactt ctgacactgg
    10561 ttattctatg gctgatgttg ctggacataa tgtaaagctt ggttcattta agcaattatc
    10621 tttgatcgat aaacatgccg atgaagaaat ttctggaatt aatttcaagg caggacgctc
    10681 agtggcagtc ttgattgacg ataagttagc tggtgtcttc atcttacaag ataaagttag
    10741 aacagactct aaagcagctt tggctgaact caagaaacgt ggcgttcgcc caattatgtt
    10801 aactggtgac aatcaaaaga ccgctgctgc agtggcagaa caagttgatt taactggtaa
    10861 agtaatttcg attcacgatt tcaatgaaaa tactgatatt aatgatttgg ccggtattgc
    10921 tgatgtttta ccagaagata aactcaagat ggtaaagctt ttccaagaaa aaggctatat
    10981 cgtagggatg acaggtgacg gagttaacga cgcgcctgca ttaaaacaag ctgaagtagg
    11041 aatcgcagtt tcaaatgctg ctgacgtagc taagcgttcg ggtaaaatgg tattactaga
    11101 cgatggtcta ggctcaattg ttaaaatttt agacgctgga catcgcgtat accaaagaat
    11161 gactacttgg tcactaacca agcttgctag aactgctgaa ttaacgatgc tgttaacttt
    11221 tggctatctt ttctttgact acatcccaat ggccttgaat gcaatggtta tctataccat
    11281 tatgaacaat atggttacga tgatgattgg aactgacagg actcacatta cttataagcc
    11341 agaaaactgg aatatggcta agcttgctaa gatcgccttt tcactagctg ctggttggac
    11401 tttaattggt attgggtttg tttggttctt aaacacacac ggttggagtc acggtgctgt
    11461 ttctactatg gtttacgtat acctagttct tagcgcaatg ttgattgttt tgattactag
    11521 aactcgtaag tacttttggc aagattaccc atccaagttg gttggtagtg ttcaaattgc
    11581 agatgttcta ttgaccttta tcttagctct ttgtggttgg gcaatggtcc agatttccat
    11641 tcaaaactta gcaattactg taattgtagc gattattgct gccataataa tcgacttaat
    11701 ttaccaacct gtgatgaaaa acaggtatat tattaccata aattttataa attaaaagac
    11761 ttctaggaac tttgaactct tagaagtctt ttaatttatc tttttgattc acgatatcct
    11821 gctgcacgtg ctgctgcttt actcttgaag aaaactgcat tttcacgatt cattcgataa
    11881 ttatgaccgc gcattacgtg aaagattttt gatcgtttat tatcaacaat tctgtaatta
    11941 ctggtataaa tcttagtttt atcacgatat tgatgctttc tccttctgtg atgaatagct
    12001 gcattaacaa ctgatgtcga cccctgcaaa tttgcaggca gaacactgat ttctcccact
    12061 aacatcagaa atgcaacaat agtcacaacc caattcttgc atcttttcat aaaaacactc
    12121 ccttaatatg tcactatatt tatatagtat acgtttatat atgaagtgtt cctacgttta
    12181 ttagaaacta gtttgaaact gtcaaatctt ttgtgtaaat agttctttct cgtaaattga
    12241 ttttttaatt atttatttaa tcaaagtagg attctaaggt gtcctgaacc tgaccaaagc
    12301 ctttatgaat tcgattgaaa taacggtcat tgtagctcat tgcctgaat
//
