LOCUS       c00049_gnlPro..        12393 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BEAFEAND_54.
ACCESSION   c00049_gnlPro..
VERSION     c00049_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 03:57:29
            Original ID  :: gnl|Prokka|BEAFEAND_54
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12393
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..150
                     /locus_tag="ctg49_1"
                     /transl_table=11
                     /translation="KAEFPTEPALYAFIGHQAISYNDPYFHRNHKGLGPVQDPLKSYFD
                     LINN"
     protocluster    1..12393
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3990:6525]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3991..6525
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..12393
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12393
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             285..599
                     /locus_tag="ctg49_2"
                     /transl_table=11
                     /translation="MKRCKNWVVTIVAFLMLVGEISVLPANLQGSTSVVNAAIHHRRRK
                     HQYRDKTKIYTSNYRIVDNKRSKIFHVMRGHNYRMNRENAVFFKSKAAARAAGYRESKR
                     "
     CDS             complement(640..2940)
                     /locus_tag="ctg49_3"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNVKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGKVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNRYIITINFIN"
     CDS             3069..3917
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     75.6; E-value: 7.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg49_4"
                     /sec_met_domain="LysR_substrate (E-value: 1.8e-29,
                     bitscore: 92.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.1e-24, bitscore: 75.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDVGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQPKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIAA
                     I"
     CDS             3991..5220
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_5"
                     /sec_met_domain="Amidinotransf (E-value: 2.5e-109,
                     bitscore: 355.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQ
                     LLLNYLQELLTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQ
                     QAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELV
                     LNNHVLAVGISQRTSATAITDLAHNLFDHSSYDTILAIKIPHNHAMMHLDTVFTMINYN
                     QFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDP
                     IAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRC
                     MSCPLIREDL"
     CDS             5231..5662
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_6"
                     /sec_met_domain="OTCace_N (E-value: 5.6e-38, bitscore:
                     120.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWKWVMAAIMLPTVF"
     CDS             5623..6525
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_7"
                     /sec_met_domain="OTCace (E-value: 5.5e-47, bitscore: 149.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 2.6e-20, bitscore:
                     63.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGDGRDNVADSLLVCGSMLGVNVHIVTPKPLFTHPDVQKIAQNFA
                     QDSGSKNLITDDIAQGVKGANVVYTDVWVSMGENDWSERIKLLKPYTVTMKMMQMTGTP
                     DDQLIFMHCLTAFHDRTTQVGEEIYEKYGLNEMEVTDEVFNSKYAWQFTEAENRLHSIK
                     AVMAATLGNLFIPIACGGGGILVIVKDGHLRGVAGVIHKDFSAAKMAEDINADELVILT
                     TVDHAFLNYGKENQQAIGKIKVEQLKQYLAAGYFAAGSMKPKIEAAIEFVEKTGNLAII
                     TSLSNANKLADGVGTIIYN"
     CDS             6539..7075
                     /locus_tag="ctg49_8"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDINMNI
                     PGPIKNNRYLTKMFMLGINELENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFENQISLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPAKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             7155..8357
                     /locus_tag="ctg49_9"
                     /transl_table=11
                     /translation="MNKFIDVRIGISMELKKNKNNLKQITALIQYAFLKNNDLTKDENF
                     MSRYDHSTGYGYFDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASYPEYRGQGHISQL
                     MKEILHDLHRQDIPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIV
                     RGKWDNLAVQNGVIQLYERQLHTDDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERP
                     ISYLIYRIRDNTFLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPE
                     QNELQVDLRPYMMSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRK
                     VAVERKEDALVDFSGSITAWTQVLLGRLTMNAAVKLGLITDYRIKKLDFVKGDVSFYDY
                     F"
     CDS             8373..8534
                     /locus_tag="ctg49_10"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             8536..9141
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_11"
                     /sec_met_domain="LysR_substrate (E-value: 1.7e-12,
                     bitscore: 37.3, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHDGAFA
                     KLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDMTCFI
                     VAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAALLVASRSGYFILNENTARLINTTDL
                     QPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             9197..9307
                     /locus_tag="ctg49_12"
                     /transl_table=11
                     /translation="MKADSYILHSGDDFYAKKNFVTFNINGTCFRINWFG"
     CDS             9273..9779
                     /locus_tag="ctg49_13"
                     /transl_table=11
                     /translation="MVLVLGLTGLASQVETVDASTYGNGVQVTIPKKMQGTWYSYDRNA
                     HNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWMSGKTTKMKNDT
                     FYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKLAKKMKDYKFKK
                     VNYTL"
     CDS             9845..10537
                     /locus_tag="ctg49_14"
                     /transl_table=11
                     /translation="MTKLILGGEVMKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTS
                     QENEPGTLFMQTSHDEETTNFVVECYQDEASYDTHANSKQFKDFTDVAKDILTSRVKVE
                     LFPEFISTKAEKLAVTGSNDYVIYLTEIGVSLGKGDEFAHAVMKEMKTAVEEEKDILAM
                     IAGTVADQPNEWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKLQPDVIVD
                     QGAIFYQP"
     CDS             complement(10635..10763)
                     /locus_tag="ctg49_15"
                     /transl_table=11
                     /translation="MKGMRTLIKLLLIGGSFLTLGLMAISSVLINKPAVAKVKHRH"
     CDS             11107..12147
                     /locus_tag="ctg49_16"
                     /transl_table=11
                     /translation="MPGIVEQTLLEQQNIDLNEMVTMNQMIDQLLPNASKELQQKLKIK
                     IYNFVRTRKQPSITVRRRKYFKPAVAKLIIGNVQDYADAIERRAKEAPAKEDATDKRPA
                     SKSKRVKTITKRKILAKVIKNDKIDKSIQKKLEDKIASIVKTNFIKPVNKRGSFSVEDG
                     EKVIAELSPFYQNIKIDQKYRKNAEKAAENKETETKEKPEQHSKDQNESREGQSKDFER
                     KNNQKNSNNRNNNNQTQNQRKRQNKHPFEIRRENNNRSRNNQSNRRYNNRNNYDNRNNY
                     EFDEASGLRERYNTVIRNYNQLEQRYNALQDKYNQALDDKARLIEEMGKKNEDLRRVLI
                     DVLRKM"
     CDS             12321..12392
                     /locus_tag="ctg49_17"
                     /transl_table=11
                     /translation="MSLKELFKSNVFRGNCQIFCVNRF"
ORIGIN
        1 aaggcagagt ttccaaccga accggcgctt tatgctttta ttggccatca ggcaattagc
       61 tacaatgacc cttatttcca tcgaaatcat aaaggccttg ggccggttca ggacccctta
      121 aaatcctact ttgatttaat aaataattaa aaaatccatt ttccaaaaaa aaccatttac
      181 cccaaagatt tgacagtttc aaactagttt ctaataaacg taggaacact tcatatataa
      241 acgtatacta tataaatata gtgacatatt aagggagtgt ttttatgaaa agatgcaaga
      301 attgggttgt gactattgtt gcatttctga tgttagtggg agaaatcagt gttctgcctg
      361 caaatttgca ggggtcgaca tcagttgtta atgcagctat tcatcacaga aggagaaagc
      421 atcaatatcg tgataaaact aagatttata ccagtaatta cagaattgtt gataataaac
      481 gatcaaaaat ctttcacgta atgcgcggtc ataattatcg aatgaatcgt gaaaatgcag
      541 ttttcttcaa gagtaaagca gcagcacgtg cagcaggata tcgtgaatca aaaagataaa
      601 ttaaaagact tctaagagtt caaagttcct agaagtcttt taatttataa aatttatggt
      661 aataatatac ctgtttttca tcacaggttg gtaaattaag tcgattatta tggcagcaat
      721 aatcgctaca attacagtaa ttgctaagtt ttgaatggaa atctggacca ttgcccaacc
      781 acaaagagct aagataaagg tcaatagaac atctgcaatt tgaacactac caaccaactt
      841 ggatgggtaa tcttgccaaa agtacttacg agttctagta atcaaaacaa tcaacattgc
      901 gctaagaact aggtatacgt aaaccatagt agaaacagca ccgtgactcc aaccgtgtgt
      961 gtttaagaac caaacaaacc caataccaat taaagtccaa ccagcagcta gtgaaaaggc
     1021 gatcttagca agcttagcca tattccagtt ttctggctta taagtaatgt gagtcctgtc
     1081 agttccaatc atcatcgtaa ccatattgtt cataatggta tagataacca ttgcattcaa
     1141 ggccattggg atgtagtcaa agaaaagata gccaaaagtt aacagcatcg ttaattcagc
     1201 agttctagca agcttggtta gtgaccaagt agtcattctt tggtatacgc gatgtccagc
     1261 gtctaaaatt ttaacaattg agcctagacc atcgtctagt aataccattt tacccgaacg
     1321 cttagctacg tcagcagcat ttgaaactgc gattcctact tcagcttgtt ttaatgcagg
     1381 cgcgtcgtta actccgtcac ctgtcatccc tacgatatag cctttttctt ggaaaagctt
     1441 taccatcttg agtttatctt ctggtaaaac atcagcaata ccggccaaat cattaatatc
     1501 agtattttca ttgaaatcgt gaatcgaaat tactttacca gttaaatcaa cttgttctgc
     1561 cactgcagca gcggtctttt gattgtcacc agttaacata attgggcgaa cgccacgttt
     1621 cttgagttca gccaaagctg ctttagagtc tgttctaact ttatcttgta agatgaagac
     1681 accagctaac ttatcgtcaa tcaagactgc cactgagcgt cctgccttga aattaattcc
     1741 agaaatttct tcatcggcat gtttatcgat caaagataat tgcttaaatg aaccaagctt
     1801 tacattatgt ccagcaacat cagccataga ataaccagtg tcagaagtaa atggagtaaa
     1861 gttttcagca ttcatgactg gaatgttatt ttctactaag tattcatcga ttgctgtatc
     1921 gataatacca gcattacgtt tatcagttgc ggctccagct aaagcaagca cgtctttgtc
     1981 aggcaagtca cttagatcag tccaagcggc tacggcagtt ttgttttccg taattgttcc
     2041 agtcttatca agtaaaagca agttcaagtt agctgcgtcc tgaattccag ttaggtcaga
     2101 agtcaggact ccttctttac ttaagcgggt tgcttcaaat gagttggata aagcaaaagt
     2161 tgatggcatt gctacaggaa ttgaagcaat aaacatcatt gccaggaatg gcaacatatt
     2221 aataaaggta ttgaaattac cgcctttgaa gaaggaggcg ataataataa ctaaggttaa
     2281 aacaccatct agtaagcaaa ggtagtagat aatcttagtc aaaagttgtt gtaagtgacc
     2341 aggagcagcg gaattgttga tcaaattaat cgtcttaccg cttctagaat ctttacctgt
     2401 agcagtaaca acagctaggc catcaccttc aacaactgta gtaccggcaa aggcggtgtc
     2461 atcaattgct ttcttaactg gtttagattc acctgtaatt gagctttcat cacaagctaa
     2521 gttaccgtca acaattttaa catctgctgc gagtacgtcc ccgcgtttaa gtgagattaa
     2581 atcgccttta actagttgtt tagaatcaag tttgatccac ttgccatcgc gttcaactga
     2641 tacagtagga gtcaacttgt gtgaaatatt atttaaaact cgtcttgatt gctttttctt
     2701 agatgcaccg ttaaatgcag caaataaaag catcaacaac acgaataatg attggaccca
     2761 tttgcccaag atacattcta gaattaaagc agcttctaga atccaagcgg ataggttcca
     2821 taacttagac aagaactctt taaagaaatt gtattcaggc tctggtactt catttaagcc
     2881 atcttctttt aagcgcttgt ctgcttcggc ttgagttaag ccgtgaaatt tatcagacat
     2941 tattttccct ccaaatctac cttaataagg tagcacagat attgctatga ataaaatact
     3001 aaaatacaat ataagatatt aaatatttta atatcactat caattgaaat aaaaaaagga
     3061 taaataatat gaatctaaaa cagttacgtt attttctagt tgtagcagaa gaaaagcaga
     3121 ttacagcagc tgctaagcgc ttgtatattg cacagccacc attaagctat caattaaaac
     3181 aattagagaa agagttgggc gcgcaattat ttaaaagaac ggcacatggt attgagctaa
     3241 ctgatgtggg acaaattttt caaagctatg ccaatgaaat tatttctcta gctcaaaatg
     3301 ctgaaaacca agtacataag actatttccg gtgaattggg aacgattgca attggaatgg
     3361 catcttcctc aacgggcttg ataccaatga attcttttaa tgaattacga aaatattatc
     3421 cggaaatttc ttttgatatt tatgaagata atacttatgg catcctggat aaattagaaa
     3481 aaaagacaat cgatctaggc attgtacgaa cgccttacaa ccagacaggt ttaaatacta
     3541 agactttaac aactgaaaaa atgatggcta ttagtgtaga cccagatttt cagccaaaaa
     3601 aagaattacg cattaaagat ctagcagatc agccattgat tatttatcgt cgctttgagg
     3661 atatttttaa tcaaactttt gcacatcatg ggcttaaacc attttatgcg gttaagtgtg
     3721 atgattcacg gacagcaatt acttgggcca agagaaaaat gggagtagcg ctagtaccag
     3781 aatcaattgc gacaacttat gcccaagaaa atatgatcgc aattaaacat gctaattgga
     3841 taacacattt gcagctggtt tggcgtaaag atcatcaagt tacaccttta atgaaaaaaa
     3901 tcattgctgc aatatgataa tactgtaact tttacctaat tgatccataa taaatgtaaa
     3961 cgggtacaat aattaataga aggtggttga atgtcgagtc cgattcatgt ttattcagaa
     4021 attggtaagt taaaaacggt gatgttacat cgaccgggaa aagaactaga aaatctagcc
     4081 ccagatattt tgcatcgaat gttgattgac gatattcctt atctgaagat tgcccaagaa
     4141 gaacatgatg cttttgcgca tgtattgagg cagcagggga tcaaagtatt atatcttgag
     4201 gatttattag cagaatcttt aacagatgag aaagttcgtc gggcattctt agatcagtta
     4261 ctggatgaat caagtattaa aaaacaggat cctttgcatc aattattgct gaactatctc
     4321 caagaattgc taactaagga aatggtaaaa acggtgattg ctggaattag aaaaagtgcg
     4381 attcataatt ctaccccatc tttagcagat ttggctgagg acccagatta ccctttttat
     4441 cttgatccaa tgccaaatgt atattttact cgagatcaac aggctgcaat tggttcaggg
     4501 atgaccatta accggatgac tttcagagct agacgacgtg aatcattatt tatggaaaca
     4561 attttgaaaa atcatcctga tttcaagaac gcaactattc cagtttggcg tgaccgttat
     4621 catcatggtc gccttgaggg cggggatgaa ctagttctaa ataaccatgt gttagctgta
     4681 ggtatttcac aacgcacttc tgcaactgca attactgact tagctcataa tttatttgat
     4741 cattcaagtt atgatacgat tttagcgatt aagattccgc acaatcatgc tatgatgcac
     4801 cttgatacag tttttacaat gattaattat aatcaattta cggttcatcc ctttatttta
     4861 gataaagccg gcaaaattga tatttatgtt ctacagcccg atgatcacaa cggtgtaaaa
     4921 atcacagaaa agaatgattt ggtgcaggtt ttgaaagaaa acttacattt aagcgaattg
     4981 gatttaattc caactggtgg tggtgatcca attgccgcac cacgtgaaca atggaatgac
     5041 ggctcaaata ccttggcaat tgcaccaggt gaagtcgtta cttatgatcg taattatgta
     5101 tccaatgatt tgctaagaaa acatggcatc atcgttcatg agattcggtc tagtgaactc
     5161 tcacgtggtc gtggcggtcc tagatgtatg tcgtgtccgt tgattcgtga agatttataa
     5221 gaggcaaaaa atgaaatatt tacaaaatgt ttttcaaggt agaagttttc tcgattgtaa
     5281 agactatact ccagctgaaa tttcatattt aattgatttt gcattacatt taaaagaact
     5341 taaaaaagag catatcccac atgaatatct gaaaggtaaa aatattgcac tactttttga
     5401 aaaagcctca actaggacgc gatctgcttt tgtagtagct tgtaatgatt taggtgctca
     5461 tccagaatat ctaggcgcaa gcgagatcca cttaggtaaa aaagaaagcg tcaaggatac
     5521 ggctaaagtc ctaggctcaa tgtatgatgg aattgaatat cgcggttttg ctcaagaaga
     5581 tgtagaagag ctggctaaat attctggcgt tcctgtttgg aagtgggtga tggccgcgat
     5641 aatgttgccg acagtctttt agtttgtggc tcaatgttag gtgttaatgt acatattgtt
     5701 acacccaagc ctttgtttac acatcctgat gtacaaaaaa ttgctcaaaa ttttgcccaa
     5761 gattcaggtt caaaaaattt gatcacagat gatattgctc aaggcgttaa aggagccaat
     5821 gttgtttata ccgatgtttg ggtttcgatg ggtgaaaatg attggtctga acgaattaaa
     5881 ttattaaagc catatacggt cacaatgaaa atgatgcaaa tgactggtac accagatgac
     5941 caattgatct ttatgcattg tttgacagct tttcatgatc gaacaactca ggtgggagaa
     6001 gaaatctatg aaaaatatgg cttaaatgag atggaagtaa ctgatgaggt ctttaattca
     6061 aagtatgctt ggcaatttac agaagctgaa aatcgattgc attcaattaa agcagtgatg
     6121 gcggctactt taggaaattt atttattccg attgcctgtg gcggtggtgg catccttgtt
     6181 attgtgaaag atgggcatct cagaggtgtt gccggcgtaa ttcataaaga tttttccgct
     6241 gctaaaatgg cagaagatat caacgctgat gaattagtaa ttctaacaac ggtggatcat
     6301 gcatttttga attatggcaa agaaaatcaa caagcaattg gtaaaataaa agttgaacag
     6361 ctcaaacaat atctagcagc aggttatttc gcagctggga gtatgaagcc taagatagaa
     6421 gctgcaattg aatttgtaga aaaaacaggt aatttagcaa ttatcacctc tttgagcaat
     6481 gccaacaaac tagcagacgg agtcggcaca atcatttata attaactggg tgataaaaat
     6541 gaatattttt aatgaaggaa aaaagcagga tattgcccaa gttttagcag ctaaagatag
     6601 gcgagtagct gtacaacata agatttttaa taagtatcct aatcaaactc tagtcgacat
     6661 taatatgaat atcccaggac caatcaagaa taatcgctat ttaactaaaa tgtttatgtt
     6721 gggtatcaat gagctggaaa atgcttggac taacctaggt tatcatttta aattggtgac
     6781 acagcttaat gatgatagtg gctgtgaaaa cttttatgta ttatctttgt caattgaaaa
     6841 agtaaagcgc tcaacaattg attttgagaa tcagatatca ttgggacgtc tctttgatgc
     6901 agacgtgttg gtaaaaaata aacaagctgc aatttcacgc agagatttgg gcaggcagcc
     6961 acgtaagtgc tttttatgtg atcgccctgc taaagaatgt gctcgcagcc ggagacattc
     7021 agtggaacag atgcaggcat ttatctctca gctttatcaa gaatacgttg cgtaaaataa
     7081 accgggattt tatgattccg gtttattttt atgaaaaatc tagttaaaaa tttaaaaaat
     7141 gaactaaaat agtaatgaat aaatttatag atgtacgtat aggaataagc atggaattaa
     7201 agaaaaataa gaataattta aagcaaatta cggcattaat tcaatatgca tttttgaaaa
     7261 ataatgattt gactaaagac gaaaatttta tgagtcgtta tgatcatagt acaggttatg
     7321 gctattttga taaggaaaaa ttagctagct atattatggt taatcgattt aaaagtgatg
     7381 tttttgggca tcatttaccg atggctggaa taggttatgt agcttcatat cctgagtatc
     7441 gtggccaagg tcatatttcc caattaatga aagaaatttt gcatgactta cataggcaag
     7501 atattccgtt tgctaacctg gcaccatttt cggagagctt ttatcgccag tacgggttta
     7561 gcaatagtat ttatcaaaaa gaatatcgct ttgatggaag cgcattgcgt agttttaaat
     7621 taccacgttc tggtcatata gtgcgtggca agtgggacaa tttagctgtt caaaatggtg
     7681 tgattcaact ttatgaacgt caactgcata ctgatgatga acgtaacacg gttgtacgtg
     7741 aggcatggtg gtggaataga cttgattctt attatcatca ccgcaatgta gccgtttatt
     7801 ttgacgcgga tgagcggcca attagttact tgatttatcg cattagagac aatacttttt
     7861 tagctgatga aatgtacgca attacgccgc agggattact gagtatgttt ggttttatgg
     7921 gttcgcacgc gggcagtgtt aagcaattta aaatgagcgt accagagaaa tcgttacgag
     7981 ctgaactttt tcctgaacaa aacgaactcc aagttgattt gcgtccttat atgatgagtc
     8041 gaattattga ttttgaaaaa gttttggctt gtatgcggcc aatgcaagaa ggtgatttta
     8101 atctggaagt caatagcgat gaacagtgtc cttggaatat tggagtttgg caattaagta
     8161 atcatggacg taaggtagcg gtagaacgta aggaagatgc attggttgat ttttcgggat
     8221 caattaccgc gtggacccag gtgctattag gtagactaac catgaatgct gctgttaaac
     8281 taggattaat tacagattac cgcatcaaaa aattagattt cgttaaaggc gatgtatcat
     8341 tttatgatta tttttagttg tgaggttaaa aaatgagtaa agaaaagaaa ctcaatttaa
     8401 taaaattatt tggcattgta gttagtggtt tgaatttgat cttttttgcc ttgatggcac
     8461 ttaataagca tgaagatact aaggataaaa gaagagtagc agaagaagga cacgcaccgc
     8521 tggatgaaaa ataaaatgac ggaattaaag attgcatatt ttgaccaatt aggtcgtaag
     8581 gaattagatc aggcagtgca gcattttgtg ttaaaacatc ctaatgtaga tgtaaaacta
     8641 cttgcgacta gtcatgatgg tgcttttgca aaactgaatg aagatgaagc agacatagca
     8701 atcaatgatt tgcgtgacga gaatcttaac tttgatgaaa cagaattgac tcaagctggt
     8761 gtaatggcaa ttttgcccaa gggaatgtat cctaatggca ttcaaatgat tgaaaaagac
     8821 gagctcaatg atatgacttg ttttattgtg gctaaacctg aagaagaggt tagtgagcta
     8881 catttattta aagatttgta tcaaattggc agtcaattca tcgcttctaa ctcggtcgaa
     8941 gaagcagcac tgttggtcgc ctctaggtct ggctatttta ttttaaatga gaatacggct
     9001 aggttaatta atactacaga tttgcagcca cttttcttgc ttgatcatgg tcagttaata
     9061 aagcaaaaga taatggcttt ttataagtca aattcagcgt taagtagtga gtttataaag
     9121 ctattgcagc aagaatatta atctgtaaag ttaaaaatat cttgtctaag tactataaga
     9181 tactgtaaaa tatattatga aagcggactc atatatttta cattctggag atgattttta
     9241 tgctaaaaag aactttgtta cctttaacat caatggtact tgttttagga ttaactggtt
     9301 tggctagtca agttgagact gttgatgctt caacttatgg taatggtgta caggttacta
     9361 ttccaaaaaa gatgcagggt acttggtact cttatgatcg taatgcacat aatggcacaa
     9421 agatcacctt tactgaacat actgttaatg gcaaaccaat atttacccag gaggcttcga
     9481 caattagtga ttacttcaat ggtagaattg ctaaccagaa gaactttgat aaggtaacgc
     9541 aaaactggat gtctggtaaa actaccaaaa tgaagaatga tacattctat gagattgatc
     9601 cgtggattac ttttgaaaat tggagtcttt atcgagtggt accacaaacc attaatggta
     9661 aaaagcataa cgtgctggtt tattctagta gatatgatgg tggtaactac ttcagaagca
     9721 agaaattagc taaaaaaatg aaggactaca agtttaagaa agttaattac acgttatagt
     9781 tttgtgacat cccttaacta agggatgttt tttactaata gacgcgataa aatttagtat
     9841 aataatgaca aaattaattc ttggaggaga agttatgaaa ttaaaacaaa caccaatttt
     9901 gcgtttatat aaactagaaa ctaataaaga ggatcatgca aagttcgtta aggcagggca
     9961 acataatatg cttacttctc aagaaaacga accaggcaca ttgtttatgc agacaagtca
    10021 tgacgaagaa actactaatt ttgtagtaga atgctatcaa gacgaagcaa gttatgatac
    10081 tcatgctaat tcaaagcaat ttaaggattt tactgacgtt gctaaagata ttttaactag
    10141 tcgagtaaag gtagaattgt ttccggaatt tatttctaca aaggcagaaa aactagcagt
    10201 taccggatca aatgattatg ttatttatct gactgaaatt ggtgtttctt taggtaaggg
    10261 cgatgagttt gctcatgctg taatgaaaga aatgaaaacg gcagtcgaag aagaaaaaga
    10321 tattttggca atgattgcag gaactgttgc cgatcaacca aatgaatggt tagctattga
    10381 agtttatcgt aataatgaag cttacaagca gcacttggaa actaagaact tcaaagagta
    10441 tttgaataat acaaaatatt gtgttgaaag taagagttta cgtaagttgc aaccagatgt
    10501 aattgttgac caaggtgcaa ttttctacca accataaaga ataagacgaa aagaagacca
    10561 ggctatgtgg agtacataac ctggtctttc tagttagagg ggaaaagatt tattaacata
    10621 tattattctg gtttttagtg gcgatgtttt acctttgcta ctgctggttt attaattaat
    10681 actgagctga tggccattaa accaagcgtt aaaaatgatc caccaattaa gagtagttta
    10741 atcaaggttc tcattccttt catcttaatt gatcttataa tagcgaaata atattaagaa
    10801 tttatatgta aaacctaatg gattagttaa gaaaataaaa ctagaaaaaa ggctggttag
    10861 cacgtaaaat agaaatagag tcaaagtcta gtgcaactgc gcataaaata aagcagtatc
    10921 gatgggatgc tgcttgtttt ggttaaaaaa tagagaatat gcttgtagcc cttttcgtaa
    10981 atagcgttaa tgttgtaaaa tggaaagtgc attaagttta ttaatgagaa aattgatgta
    11041 ttattgcaaa ataggccgta atggcccttt ttgttgtgaa aaaattaaaa gaatatagga
    11101 ttggaaatgc caggaatagt agagcaaaca ttattagaac aacaaaatat tgatttaaat
    11161 gaaatggtaa caatgaatca aatgattgat caattgttgc ctaatgcaag taaagaatta
    11221 caacaaaaac taaagattaa aatttataac tttgtgcgta cacgtaaaca accaagtatt
    11281 actgtgcgaa gaagaaaata ttttaagccg gctgttgcta aattaattat tggtaatgta
    11341 caagattacg cagatgcaat tgaacgtcgt gctaaggaag ccccagctaa agaggatgct
    11401 actgataaga ggccagcttc taaatctaag cgggttaaga caattactaa gcgtaagatt
    11461 ttagctaaag ttataaagaa tgataagatt gataaatcta ttcaaaagaa attagaggat
    11521 aagattgctt caattgtgaa gaccaacttt attaagccag ttaacaagcg gggaagtttt
    11581 tcggttgaag atggtgaaaa agttatagct gaacttagtc ctttttatca aaatatcaag
    11641 attgatcaaa agtatcgcaa gaatgctgaa aaagcggctg aaaataagga aacagaaact
    11701 aaagaaaagc ctgagcaaca ttctaaggat cagaatgaaa gtcgtgaagg tcaatctaag
    11761 gactttgagc gtaagaataa tcagaagaat agcaataatc gaaataataa taatcaaacg
    11821 caaaatcaac gtaagcgaca aaataagcat ccttttgaga tcagaagaga aaataataac
    11881 cgctcacgta ataatcagtc taaccgccgc tataataatc gaaataatta tgataatcgg
    11941 aataattatg aatttgatga agctagcggt ttgcgtgaac gctacaatac agtaatcaga
    12001 aattacaatc aactggagca aagatataat gctttgcaag ataaatataa tcaggcttta
    12061 gatgataaag ctagattgat cgaagaaatg ggtaagaaga acgaagactt acgtcgtgta
    12121 ttgatcgacg ttttgcgaaa aatgtagttt ttggtaaaca aagagactag tagtcaattt
    12181 gaattgatta ctagtcttat tttatgttta tgaaatatga tttagcttaa aaattaaaaa
    12241 aatatgtgta aaaaattatt tttgtgtagt aagattaaag gatgataaat atttttatta
    12301 atgattaatg gaggagaagt atgagtttaa aagagctatt taaaagcaat gtgtttcgag
    12361 gaaactgtca aatcttttgt gtaaatagat ttt
//
