LOCUS       c00064_gnlPro..        15338 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GECJGNHB_67.
ACCESSION   c00064_gnlPro..
VERSION     c00064_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 04:26:22
            Original ID  :: gnl|Prokka|GECJGNHB_67
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15338
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15338
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2245:5338]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2246..5338
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15338
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15338
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(310..591)
                     /locus_tag="ctg64_1"
                     /transl_table=11
                     /translation="MSRRKKQLAQIFRIATTARNAYQVLGKWKMSLLDWRGTKKIPFRR
                     TIREIQSKWLPDGLPRRGYVKLDKATSTQIVRSSPVLEFMICSAVVAK"
     CDS             complement(707..1867)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:Iron-containing alcohol dehydrogenase (Score:
                     445.5; E-value: 4e-136)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg64_2"
                     /sec_met_domain="Fe-ADH (E-value: 9.6e-137, bitscore:
                     445.5, seeds: 219, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTGLRTDFQMPSVNLFGQGTAEEIGNRLKNLGCRRPLIVTDEGL
                     HQLGYSEKIAAYIKEAGLEVAIYPKAEPNPTDKNVEDGLKTYHEENCDSIVSLGGGSAH
                     DCAKGIGLVAANGGKIHDYEGLDRSEKPMVPLVAINTTAGTASEMTKFTIITDTSRKVK
                     MAIVDKHVTPVLSINDPLLMVGMPPSLTAATGLDALTHAVEAYVSTAATPVTDACAIKA
                     IQIIPQYLPKAVANGNDMEAREQMVYAQYLAGMAFNNASLGYVHAIAHQFGGFYNLPHG
                     VCNAILLPHVCRFNLIARKERFAEIAVALGEKTDGLSVDEAAEKAITAIERLAAQLNIP
                     KGFKELGAKEEDIEILAQHAMQDACAATNPRKPTQKEVEAIIKAAM"
     CDS             2246..4510
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg64_3"
                     /sec_met_domain="Gly_radical (E-value: 9.3e-46, bitscore:
                     144.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 4.9e-299, bitscore:
                     982.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQLLTKATLSKKQWEGFKGGNWQKEIDVRDFILKNVTPYEGDE
                     SFLAGPTEATLKLWDQVMELSKQEREKGGVLDMDTKIVSTITSHGPGYLNKELEKIVGF
                     QTDKPFKRSMMPFGGIRMAESALKSYGYEIDPEIKHIFTEWRKTHNQGVFDAYTPEIKA
                     ARHAGIVTGLPDAYGRGRIIGDYRRVALYGVDYLIEQKKKDLDLIGCGLMTEEVIRERE
                     EHSEQIRALQELKQMAQSYGFDISEPASNAHEAFQWLYFAYLAAIKEQNGAAMSLGRTS
                     TFLDIYIERDLKNGVLTEREAQELVDHFVMKLRLVKFARTEDYNELFSGDPTWVTESIG
                     GMALDGRTLVTKNSFRFLNTLDNLGPAPEPNLTVLWSTKLPDKWKQYCAKMSIKTSAIQ
                     YENDDLMREEYGDDYGIACCVSAMRIGKQMQFFGARANLAKALLYAINGGVDERYKMQV
                     APPFQPITSEYLNYDEVMEKYDRMLDWLAGVYINALNIIHYMHDKYSYERLEMALHDRN
                     VLRTMACGVAGLSVAADSLSAIKYAKVKVIRDEDGLAVDYEVEGDYPKYGNNDDRVDQI
                     AVNLVKSFMQKLQKYPTYRNAVHTSSILTITSNVVYGKKTGSTPDGRKAGEPFAPGANP
                     MHGRDSHGAVASLTSVAKLPYKYSLDGISNTFSIVPEALGHEEETQVSNLDGMLDGYMA
                     KKAHHLNVNVLHRETLLDAMDHPEKYPQLTIRVSGYAVNFIKLTREQQLEVINRTFHEM
                     M"
     CDS             4601..5338
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.9;
                     E-value: 6.1e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg64_4"
                     /sec_met_domain="Radical_SAM (E-value: 8.9e-38, bitscore:
                     120.3, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMTTRIHSTESFGTVDGPGIRYVVFTQGCPLRCKFCHNPDTWKI
                     NEGNEMSVEEIMSDVRDYLPFIEASGGGITVSGGEPLLHLDFLIELFKACKEIGVHTAI
                     DTAGGCFSRSPRFMEKLDELMKYTNLVLLDIKHIDPEKHKWLTGMSNEHILDFARYLAD
                     KHIPVWIRHVLVPGVDSEEDLQKTSDFIHSLPNVEKIEILPYHKLGVYKYEALGIDYPL
                     KGVEPPTKEQVAHAEHILKRELQ"
     CDS             complement(5714..6271)
                     /locus_tag="ctg64_5"
                     /transl_table=11
                     /translation="VKILGISGSLTGEKTSIGVYEVLMAIKAEDPEAETELLDLKDYEV
                     EFARGFPLSYYNDDTIAAVNKMLEADILVFGSPIYQASITGALKNLLDHLHRDAFQSKV
                     CGIVMNGGSDKHFLVAEYQLKPVLTFLKATCAVRNVFIHNDDFNEDNEIINTDIQARIR
                     KLAHELLQLRKAFSGGNPGNLG"
     CDS             complement(6290..6823)
                     /locus_tag="ctg64_6"
                     /transl_table=11
                     /translation="VFQRFVVGMGIAVFMFIAGVTYFYFNKGEAIATEAAPSKKPAAEE
                     ETAAKAVIQESFCQKTPERKLSAYKSMSEEALVQEVHNMTHQKVAANEKWGASEITKEK
                     VDALYSAISNQTFADTELQDMLLGILKPWKKGDFSNAVKAHNEIWAYQKGNIGKAERRL
                     TPSEEAAYIKENFK"
     CDS             complement(6942..7922)
                     /locus_tag="ctg64_7"
                     /transl_table=11
                     /translation="MIQLIYNEQLKLWKKKRILVIILIIACLVPIFTYAQYKESKALQE
                     KIGTTDWRVKLQKQIVDTQNRLGSASLSDDFKKYLRITLSQEQYYLNHNINPNAPGAPT
                     FMRVFIENAIGMLLPLFVMVAASDIVSAEAGSGTIKLLLTRPVKRWRILLSKYIAMLLS
                     VSFILLCTAVFTYGISGLVFGYHGWNMPILTGFTIKGDELLTSHVHAVSQWKYLLMAFG
                     LAWFVGVVSGSLTFMLSVLLRSTAAVMGIMLSSLIAGAILTNMVSAWPSAKYLFMVNLQ
                     LTNYLNGTSPPVAGMTLGFSVAVLLVWLFLSLVVSFVVFTKRDVY"
     CDS             complement(7919..8830)
                     /locus_tag="ctg64_8"
                     /transl_table=11
                     /translation="MTTIPALKVIDVHKKIGRKEIIKGISFEVMPGEVFGFLGPNGAGK
                     TTTIRMLTGLIRPTSGKILIGGKNVRTEFTEAMKNLGCIVENPEMYPFLTGYENLAYFA
                     RMDPSIPRNRLDEVAALVGLTGRIHDKVKTYSLGMRQRLGIAQALLGNPKLLILDEPTN
                     GLDPAGIREMREFIRSLAEKAHLSVLVSSHLLSEVQLMCDKVAIIHNGQVIRTGNVHEL
                     LSEKARTFWKVAPIEKARTLLQAETQVAEGEDGLLVTPYDEEKNALWNEMLVQNGVRVK
                     EMKAVLPALEDLFLELTGGRKK"
     CDS             complement(8827..9630)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg64_9"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 1.2e-27, bitscore:
                     87.4, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKHLISAISIVSAVSALLFLAGLWMVFEDQQTKATGVKTETART
                     GNNTSKAGGTKQITITAIGDSLTRGTGDTAGKGYAGDAADRLKKKTKKAVLLQNNGIKG
                     LTSSGLLEQLKQPQIKRELKSADIILLTIGGNDLFAGGEALDHLNTAYIEKLEKPYLAN
                     LKQIYAGIRAVNKTAIVYHVGLYNPFIDLSEAKTTSAIVRKWNFDSASVASDFPKVIYV
                     PTFDLFEQNVNDYLYSDKFHPNTAGYQLIGERVASLIHYREEKAK"
     CDS             complement(10050..10280)
                     /locus_tag="ctg64_10"
                     /transl_table=11
                     /translation="MLLFFGKFILLYLFLSIAFALFKVLYYNIGKKFVSKTADGTILHW
                     ALSVFVKNGTKMDSNDYFVMAVLAALFAIYL"
     CDS             10917..11897
                     /locus_tag="ctg64_11"
                     /transl_table=11
                     /translation="VLNTHNDIKQTYYAEIKEKKISSYGAYAKKGKGVKHEIGKIYFAS
                     DLLRGKEKKLYKKSGKVKVYNMFTSLMTYEDLKSHPKERQTEILTKWRETYSENEIIEA
                     LGIEEEVYYQLLTDLGLEMKKKRTIPHSKPDADPNQVIPFNDLKKLPKKDQWLLISEYT
                     EKWNAQSIAKIWGKRDSSVHNYKHNLKKLALKNGWIDEYKKDKAQENIKDFTPAAVESG
                     QEPAGNAGDERVDQLMSEFKEMKMLINNLLSSNNQVAVEETEKIAERDATENEENNEKP
                     ESFTMNYENETEGFIIFQDLKRFIAVLEKNPDRFKVEVKLTRIEE"
     CDS             complement(12303..13340)
                     /locus_tag="ctg64_12"
                     /transl_table=11
                     /translation="MGEVLILEKKVNYLPGTDYDGLWKKIISELFEEFILFFAPDLYET
                     IDFGKGIVFLEQELHKVIIKHKKGKRIADKIVKVSLKNGEEKYVFIHIEIQEKQDPDFS
                     KRMFTYFYRLFDRFQENIYSIAILTDLSKSNNSEPFQYSFYGTELTYRFNTYKFNEADI
                     PSLKKSTNPFAIAVLAGIYLHLTEKNYQKRYEVKKKLLKEFILSNQNLSSNYAEALCYF
                     IDYLLYLPGELTKQLTKELFIHIEKEANHMLYSEELKEAPTFAEYLKTVKEEGIEIGIE
                     KGIEKGIEKGKEEGIEIGIEKGKMEEKRNLAAELLREGFSVEKVAKMVKLSIDEVKKIK
                     KCVNN"
     CDS             13886..14572
                     /locus_tag="ctg64_13"
                     /transl_table=11
                     /translation="MIVEDDVKIARVLELELQHEHYDTVWVENGSQALNLLESEDWDLV
                     LLDVMIPCLSGLEVLRRYRMRNSRTPVILLTARNSVLDKVNGLDHGANDYITKPFNIEE
                     LLARIRAALRTGALHTGKSENSKKHEYALADLLVNTATRQVTRGGKPIELTKREFDLLC
                     YLLKNKRIVLNREQLLNEVWGFEYAGDTNVVDVYIGYLRKKIDHGHETALIHTVRGVGY
                     TMKETG"
ORIGIN
        1 aagtgagcaa aaatgattaa ttcgttttat atagattaaa aaaagataag aatggagatt
       61 acttcattca acattccggt tattacagag tgggaaaaca actgcaagaa ggaaaatata
      121 gattgtcttt tgttgaccat gaaaaaacgc ataaccgaaa accatttgta caaatcacct
      181 catcagatgg tactatccgt caatcttatt catttgaaaa gaaaaaccaa agacaaatta
      241 aattgaacct taaaaatcag gaaatattag aaatccataa aggtttctca aatgaatacc
      301 aaaattacgt tattttgcta caaccgctga gcaaatcata aattccaaaa cgggcgatga
      361 acgtacgatt tgtgtgcttg tcgctttgtc taattttacg taacccctcc taggtaaacc
      421 atcagggagc catttgcttt gaatctctcg tatggttctt ctaaagggga tttttttcgt
      481 ccctctccaa tccaacaggc tcatcttcca cttgcccaga acctggtatg cattgcgggc
      541 ggtggttgca atccggaaaa tttgcgccag ctgttttttc cgtcgcgaca tggacgcctg
      601 tcttttgaaa aaaggtatag acaaaaaata cctgcaggcc ggacacttgg aaaaagtgcc
      661 cagcctgcag gtgccagttt actcaaattc ccctccgtct tcttccttac atcgctgctt
      721 ttataatcgc ttccacttct ttttgtgttg gtttgcgcgg gtttgtggct gcgcacgcgt
      781 cctgcatcgc atgctgggcg aggatttcga tatcttcttc tttagccccg agttctttaa
      841 agcctttcgg aatgttcagc tgtgctgcca acctttctat tgctgtaatg gctttttccg
      901 ccgcttcgtc gacgctcagg ccatccgtct tctcacccag tgcaacggca atttctgcaa
      961 atctttcttt ccgcgcaatc agattgaaac ggcacacatg cgggagcaaa atcgcattgc
     1021 aaacgccgtg cggcaagtta tagaaaccgc cgaactggtg cgcaatcgcg tggacatagc
     1081 ccaaagatgc attattaaac gccatgcctg ccaaatactg cgcatatacc atttgttcac
     1141 gcgcttccat atcattgccg tttgcaacag cctttggcaa atattgcgga ataatttgga
     1201 tcgctttaat ggcgcatgca tctgttaccg gtgtggccgc agttgaaaca tacgcttcca
     1261 ctgcatgggt caaagcgtca agccccgttg ccgcagttaa agacggcggc atcccgacca
     1321 ttaataatgg atcattaatg gacaaaaccg gtgtcacatg tttatctaca atcgccattt
     1381 tcacttttcg actcgtatcg gtaataatcg taaattttgt catttcgctg gcagtcccgg
     1441 ctgttgtatt aattgcaacg agcggcacca ttggtttttc agaacggtcc agcccttcat
     1501 aatcatggat tttgccccca ttggccgcaa cgagcccgat cccttttgca cagtcatgcg
     1561 cgctcccgcc gccaagtgaa acgattgaat cgcaattttc ttcatgatag gtttttaacc
     1621 cgtcttccac atttttgtct gtcggatttg gttcagcctt cggatagatc gccacttcca
     1681 ggccggcttc ttttatatag gctgcaattt tttcggaata ccccagttgg tggagccctt
     1741 catcggttac aatcagcggt ctgcgacacc caagattttt cagcctgttt ccaatttctt
     1801 ctgccgtccc ctgtccaaac aagtttacgg aaggcatttg aaaatcagta cgtaatcctg
     1861 ttaacatctt tccccactcc ttttatgtaa ctgcttacat gaaaaatata acgcaaccgc
     1921 tttcatatgg ctgtgccaat tttgtgaaat attgagcatg ttaccaaatc acaaactctc
     1981 cccaagaaaa ataatcatgt gaaaaactga tcaatttgtg ttataacacg ctttcatcgc
     2041 atttttctat tatatatcta cggccaaatg ttttgaacat tctttgacaa ctgctttttt
     2101 tggccccaaa atgtgaacgc tatcactatc tttttaaaat cgaccatgct aaaatgaaag
     2161 cgtaataaga aatgttcact atttaacaaa caaacatcca attctgaagg cagctcatta
     2221 ataggcttaa aggaggccat ttaaaatgac tgaacaatta ctgacaaaag caacgctctc
     2281 caaaaaacaa tgggaaggct tcaaaggagg aaactggcaa aaagaaatcg atgtaaggga
     2341 ctttattctg aaaaatgtaa ccccttacga aggcgatgaa agctttcttg ccggcccgac
     2401 tgaagccact ttaaaattat gggatcaggt catggaactg tcgaaacagg aacgcgaaaa
     2461 aggcggcgtc ctggatatgg atacgaaaat tgtatctacc attacatcgc atggcccggg
     2521 ctatttaaac aaagaacttg aaaaaattgt cggtttccaa accgataaac cgttcaaacg
     2581 ttcgatgatg ccgtttggcg gaatccggat ggcagaaagt gccttaaaat cttacggcta
     2641 tgaaattgat ccggaaatca aacatatttt tacagaatgg cggaaaaccc ataaccaagg
     2701 tgtattcgat gcctacacac cggaaatcaa agctgcacgg catgccggca ttgtaacagg
     2761 ccttccggat gcttacggcc gcggccgcat tatcggcgac taccggcgcg ttgcccttta
     2821 cggtgtagat tatttaattg agcaaaagaa aaaagatctc gatttaatcg gctgcggctt
     2881 gatgacagaa gaagtcatcc gtgaacgtga agaacattcg gaacaaattc gtgcattgca
     2941 agaattgaaa caaatggcac aaagctacgg attcgatatt tccgaaccgg cttcaaacgc
     3001 acacgaagct ttccaatggc tgtatttcgc gtatctggct gccattaaag aacaaaatgg
     3061 cgcggccatg agtcttgggc gcacatccac tttccttgac atttatattg aaagagattt
     3121 gaaaaacggt gtcctgactg aacgggaagc acaagaactc gtcgaccact ttgtcatgaa
     3181 actccgcctc gtcaaatttg caaggacgga agattacaat gaactgttca gcggcgaccc
     3241 gacatgggta acagaatcga tcggcggcat ggctttggac ggccgtacac tcgttacgaa
     3301 aaactcgttc cgcttcctga acacgcttga taatctcggc cctgcgccgg aaccgaacct
     3361 gaccgtgctc tggtcgacga aactgccgga taaatggaaa caatattgcg cgaaaatgtc
     3421 gatcaagaca agcgccatcc aatatgaaaa cgatgactta atgcgtgaag aatacggcga
     3481 tgattatggc attgcctgct gtgtatcggc gatgcggatc ggcaaacaaa tgcaattctt
     3541 cggcgcccgt gccaacctgg caaaagcttt gctgtatgcg attaacggcg gcgttgatga
     3601 acggtataaa atgcaagtcg cacctccgtt ccaaccgatc acatcggaat atctcaatta
     3661 cgatgaagta atggaaaaat acgaccggat gcttgactgg cttgcaggcg tttatatcaa
     3721 tgctttaaac atcatccatt atatgcatga caaatacagc tacgaacggc ttgaaatggc
     3781 attgcatgac cgcaatgtac tgcgcacgat ggcttgcggc gttgccggct tgtctgttgc
     3841 ggccgactct ctaagcgcca tcaaatatgc gaaagtaaaa gtcatccgtg acgaagatgg
     3901 ccttgccgtt gactatgaag tcgaaggcga ttatccgaaa tacggcaaca acgatgaccg
     3961 cgtcgaccaa attgccgtca atctcgtcaa gtcgtttatg caaaaactgc aaaaatatcc
     4021 gacttaccgg aacgctgtcc atacttcttc gatcctgaca attacatcga acgttgtata
     4081 cggcaagaaa acaggaagca caccggacgg ccggaaagca ggcgaaccgt tcgcccctgg
     4141 cgcaaacccg atgcacggcc gcgattcgca cggcgcagtc gcatcgttga catctgttgc
     4201 gaaactgcct tataaatatt cgcttgacgg catttccaac actttctcga ttgtcccgga
     4261 agcgctcgga cacgaagaag aaacacaggt ctccaacctg gacggcatgc tggacggcta
     4321 tatggcgaaa aaagcgcacc acttaaacgt caacgtcctg catcgcgaaa cattgctgga
     4381 tgcgatggat catccggaaa aatatccgca attgacgatc cgtgtatcgg gatatgcggt
     4441 aaacttcatt aaattgacaa gggaacaaca acttgaagtc attaaccgca cgttccatga
     4501 aatgatgtaa actgatttag gcggcatgca cctgcgtgcc cccctccccc ctattaaaca
     4561 cttaacttat ggggaatcta tatagaagga tttgattgag atgaacatga caacgcgcat
     4621 tcattccact gaatcgtttg gcacagtcga cgggcccggc atccgctatg tcgtatttac
     4681 gcaaggctgc ccgctgcgct gcaaattttg ccacaaccca gatacatgga aaatcaatga
     4741 aggcaatgaa atgagcgtcg aagaaattat gagcgatgtg cgcgattacc tgccttttat
     4801 tgaagcttcc ggcggcggca ttacagtgag cggcggtgaa ccgcttttgc acctcgattt
     4861 tctaatcgaa ttgtttaaag cgtgcaaaga aattggcgtc catactgcca ttgacacagc
     4921 gggcggatgt ttctcgcgca gtccccggtt tatggaaaaa ctggatgaat tgatgaaata
     4981 tacaaatctt gtgttattgg acatcaagca tattgatccg gaaaagcata aatggctgac
     5041 cggcatgtca aatgagcata ttctcgattt cgcccggtat ctcgctgaca agcatattcc
     5101 ggtctggatc cgccatgtgc tcgttcccgg agtcgattct gaagaagatt tgcaaaaaac
     5161 atctgatttt atccattcgc tgccaaacgt tgaaaaaatc gaaatccttc cgtaccataa
     5221 gttaggcgtc tacaaatacg aggcgctcgg catcgactat cccctcaaag gtgtcgaacc
     5281 gccgacaaaa gaacaagttg cacatgcgga acatatttta aaaagggaat tgcagtaaag
     5341 aaaaagcgcc ggctgtccgc cggcactttt ttattccgcc taaaagaacg atacaatgtt
     5401 aagaaagcgg aaaaacttag agctcctctc ccctgaaaaa ttgccggttt tttcgtcctt
     5461 ttgctggtgt cgcgttcagg cggcatggac gtctatgtta agaaagcagg gaaaagtgct
     5521 cgccttcctt cccatagagc ttctctaccc tgaaaaattg ccccggtttt ttatcctttt
     5581 gctggtgccg cgtcatacgg caagataaac ggcaaaatgg tcgccttcct tcgcctagag
     5641 cacgtctacc taagcttcgc tgatgatcca ctatcgccca tgcgcaacgg ccacggcact
     5701 aggcaaaagt acatcatccc aaatttccag gattgcctcc ggagaaagct tttctcaatt
     5761 gcaacagttc atgcgcaagc tttcggatgc gtgcctgaat atcggtattg atgatttcat
     5821 tgtcctcatt aaaatcatca ttgtggataa aaacattgcg gaccgcacag gtggccttta
     5881 aaaaggttaa caccggtttc agctggtatt cagcaacaag aaaatgtttg tccgagccgc
     5941 cgttcatcac aatgccgcat actttggact gaaaagcatc gcggtgcaaa tggtcgagca
     6001 aatttttcaa agcgcctgta atggacgcct ggtaaattgg cgagccaaaa acaaggatat
     6061 ccgcttcaag cattttatta acggccgcaa tcgtatcatc attgtaataa gaaagtggaa
     6121 accctcttgc aaactccact tcataatctt ttaaatcgag cagttcagtt tccgcttccg
     6181 gatcttccgc ttttattgcc ataagcacct catatacacc aatggaggtc ttctcaccgg
     6241 taagcgagcc ggatatacct aaaattttca ccgtttccac ttcctgatgt catttgaaat
     6301 tttccttaat atatgccgct tcttcagaag gcgtcagccg ccgctccgct tttccgatgt
     6361 tgcctttctg gtaggcccaa atctcattat gggccttcac cgcattgctg aaatcgcctt
     6421 ttttccacgg ttttaatata ccgagcagca tatcctgcag ttctgtatcc gcaaaagttt
     6481 gattgctaat tgccgaatac agggcgtcca ccttttcttt tgtgatttcg gaagctcccc
     6541 atttttcatt tgccgccact ttttgatgcg tcatattatg tacttcctgc accaatgctt
     6601 cttcgctcat gcttttgtat gccgaaagtt tgcgctcagg cgtcttctgg cagaagcttt
     6661 cctgtataac cgcttttgca gccgtctctt cctctgcagc cggttttttc gaaggtgctg
     6721 cctccgttgc aatcgcttct cctttgttaa agtaaaaata agtgacacct gcaataaaca
     6781 taaacacagc aatccccatc ccaacgacaa accgttgaaa cacagcatct ccccctttgc
     6841 ttatcatacg aaattcgtgc tgccccgtaa aaaatcctgc tttatcattg tattaatgca
     6901 gcgaaaaaat tttaccggaa attggcggaa ttccgttttt cttaataaac atcccgtttt
     6961 gtaaacacaa caaaagaaac cacgagcgag agaaaaagcc acacaagcag cacagcaacc
     7021 gaaaatccga gcgtcatgcc tgcaacaggc gggcttgtac cattgagata atttgtcagc
     7081 tgcaaattca ccataaacaa atattttgcg cttggccatg ccgataccat attggtcaaa
     7141 atggcgccgg caatcaatga ggacagcata atccccatta cggcggccgt gctgcgcaac
     7201 aagacagaaa gcataaatgt gaggctgcct gaaacgacgc cgacaaacca ggcaaggcca
     7261 aacgccatga gcaaatattt ccattgcgaa acagcatgca catgtgatgt aaggagctcg
     7321 tcccctttta tcgtaaaacc ggtaagtatg ggcatgttcc agccgtggta gccgaatacc
     7381 agtccggaaa taccataggt gaatacggca gtgcacagca aaataaacga aacggacagc
     7441 agcatggcaa tgtacttgct aagcaggatg cgccatcttt tcacagggcg cgtcagcaat
     7501 aatttgattg tcccgctgcc cgcctcagca gacacgatat cgcttgccgc caccatgacg
     7561 aacagcggca aaagcatgcc gatcgcattt tcaataaata cccgcataaa cgtcggggca
     7621 cccggcgcgt tcggattgat gttgtggttg agataatatt gttcctgact caatgtgata
     7681 cgcaaatatt ttttaaaatc atcagaaagg cttgccgatc cgagccggtt ttgcgtatcg
     7741 acaatttgtt tctggagctt aacccgccag tcggttgtcc cgattttttc ctgcagcgct
     7801 ttcgattctt tgtactgcgc gtaggtaaaa atgggaacaa ggcaggcgat aatcaagata
     7861 atgacaagaa tccgcttttt cttccaaagc ttcagctgtt cattgtatat gagttggatc
     7921 attttttcct gccccctgtc agttccaaaa acaaatcttc aagcgccggc agcacggcct
     7981 tcatttcttt cacccggacc ccgttttgaa cgagcatttc gttccataaa gcattttttt
     8041 cttcatcata aggggtcacg aggaggccat cttctccttc tgccacctgt gtctccgcct
     8101 gaagcaaggt gcgtgctttc tctattggcg caactttcca aaaggtacgc gctttttcgg
     8161 aaagcagctc gtgtacattc ccggtccgaa tcacctggcc gttatggata atggccactt
     8221 tgtcgcacat cagctgcact tcgcttaaca aatgcgaaga aacgaggacg cttaaatgcg
     8281 ctttttcggc aagcgaccgg ataaattcgc gcatttcccg gatgcctgcc gggtcaagcc
     8341 cgtttgtcgg ttcatcaaga atcaaaagct tcgggtttcc aaggagcgcc tgggcaatgc
     8401 caagcctttg ccgcatgccg agagagtatg tttttacttt atcatggatc cggccagtta
     8461 agccaacgag cgccgccact tcatccagcc tgtttctcgg aatggacgga tccatccgtg
     8521 caaaataggc aagattttca tagccggtca aaaacgggta catctccgga ttttcgacaa
     8581 tgcaaccgag atttttcatg gcttccgtaa actcggtccg tacgtttttt ccgccgatca
     8641 aaatttttcc cgaagtcggg cggatcagac ctgtcagcat ccgaatcgtt gttgtcttcc
     8701 ctgccccgtt cggcccgaga aatccgaata cctctcccgg catcacttca aaactgatgc
     8761 ctttgatgat ttctttcctg ccaatttttt tatggacatc gataacctta agtgcgggaa
     8821 tcgtcgtcat ttcgctttct cctcccgata atggatcagg gaagcaacac gctctccgat
     8881 cagttgataa ccggccgtat tcggatggaa tttgtcactg tataaatagt cgtttacatt
     8941 ttgttcaaaa aggtcaaacg tcggcacata gatgactttt ggaaagtcag acgcgacaga
     9001 agcagaatca aagttccatt ttcggacgat cgcagaggtc gttttcgcct cggacaaatc
     9061 gataaaagga ttatacagcc cgacatgata gacgattgcc gttttgttca ccgcccgaat
     9121 tcctgcatag atctgtttta aattggccaa ataaggcttt tccagctttt cgatataggc
     9181 ggtattcaaa tggtcaagcg cctctccgcc cgcaaacaaa tcattgccgc cgatggtcag
     9241 caaaatgata tccgcgctct tgagttcgcg tttgatctgc ggttgtttga gctgttcaag
     9301 cagcccgctt gatgtaagcc ctttgatgcc attgttttgg agtagaacag ccttcttcgt
     9361 ttttttcttt aaacgatccg cagcatcacc cgcatatccc tttcctgctg tatctcccgt
     9421 tccccttgtg agtgagtcgc cgattgctgt aatcgtgatt tgtttcgtac cacccgcttt
     9481 tgacgtgtta ttgccggttc tggcagtttc cgtctttacg cctgttgctt tcgtctgctg
     9541 gtcttcaaac accatccaca ggccggccag aaacaacaag gctgacacgg cagaaacaat
     9601 agagatggcg gaaattaaat gctttttcat ttcgctattc ctttctttcc tgtttataac
     9661 ttaaaggata gcaaaggaag ccgacttttt aaaatcgcgt gctttaaata aatgcacagg
     9721 gtccattcta aaaaaagcgt tgtccggttt ccaggtaaca cgctgcagaa atgtttgatt
     9781 gctgcgagct ctctcccaaa atacagggct gatgggtttt acggagacga aacggtgcaa
     9841 gttgccaagt actgtaaagg aaagcggata tagaattatg aaccggcgca gcgggattgg
     9901 ctggtgttgc ccaacagttt ttaaaaaggg atcaaaaagc gtggaaaaag ttttcaaaaa
     9961 accataataa gattaaagaa ttttgtaaga ataatgaata tccaacaaaa taaaaaaact
    10021 gctggtatat cgtggattct gggagttttt tacaagtaaa tcgcaaataa agccgccaaa
    10081 acagccataa caaagtaatc attactatcc attttcgtac cgtttttaac aaaaacactt
    10141 aaagcccaat gcaatattgt tccatcagcc gtcttagaaa cgaatttttt gccgatattg
    10201 taatacagca ctttgaataa ggcaaatgca attgaaagaa acaaataaag caagataaac
    10261 ttaccaaaaa acaaaagcat tgccgtcact cctatattta gtattcttca atcaataact
    10321 taattttacc aaaaacgtct ataagagaaa aagggacatt tgtaatggct ttcaataatt
    10381 tttgcgcaaa ttttacacaa aggtaaacaa aaatcttgat aaattgttgg tttagaagat
    10441 acattcgaca cccgaccacc ggtacgcgct cttttcgcgt caaaatcaat tatgatcagg
    10501 gacattgctt ttggcgacac atgaaaaagt aatgtttagt ccaacttata taaaaagatg
    10561 atgttttctt tgacaaaaaa gcttatcaaa ttagtgatga aattttcatt caatgtagat
    10621 aatatacata ggatctagta taatatagat agtccgttaa ttagtagaca gcttaaagga
    10681 ataagtaggt aaattggaat atcatgtata aaattggaac tcaaaaaaga attttatgta
    10741 ccttaaacaa ctggcaggag gagaaatcgt ccctgaagat caagacagca ataatagaac
    10801 aaagtccctt aaaaataact gaaaattctc caacatcaac ccaacactgt aattatttta
    10861 tagaaagaat atggaatgaa aagcgatttt caaatttatg caaaggaggt agaccggtgc
    10921 taaatacgca taatgacata aagcaaacat attatgcaga aatcaaagaa aagaagatta
    10981 gttcttatgg agcttatgca aaaaagggaa agggagtcaa acacgagata ggaaaaattt
    11041 attttgccag tgacttatta agagggaaag aaaaaaagtt atataaaaaa tcaggaaagg
    11101 taaaggtgta caatatgttt acaagtttaa tgacctacga agatttaaaa tcgcatccga
    11161 aagaacgaca aacggaaatt ttaacgaaat ggagggagac ctattcagag aatgaaataa
    11221 tagaagcatt aggtattgaa gaagaggtgt actatcaatt gttgactgat ttaggacttg
    11281 aaatgaagaa gaaacggaca attccgcact caaaaccgga cgctgatcca aaccaagtga
    11341 ttccatttaa tgatttaaaa aagcttccaa aaaaagatca atggctgctt atatccgaat
    11401 atacagaaaa atggaacgcc caatcaattg caaaaatttg ggggaaacga gattcttccg
    11461 ttcataatta taaacacaat ctgaaaaaat tagccctcaa aaacgggtgg atagatgaat
    11521 ataagaaaga taaagcacag gagaatataa aagattttac gccggctgct gtggaatccg
    11581 gacaagaacc agctggaaat gcaggggatg aacgtgttga ccaactgatg agtgagttta
    11641 aggaaatgaa aatgttgatt aataacttat tatcttcaaa taaccaagtt gccgttgaag
    11701 aaacagaaaa gatagctgaa cgtgacgcaa cagaaaatga agaaaataat gaaaaaccgg
    11761 agtcctttac gatgaattat gaaaatgaaa cagaaggatt tattatcttt caagacttaa
    11821 aacggttcat cgcagttttg gaaaaaaatc cggatcgatt taaagttgaa gtgaagttaa
    11881 ctcgaattga agaataattt ttcctgaaga atttgggcta attagaaaat caaacgaata
    11941 gccgggatgt agaatactgg cgctacaaaa attaccattg aatataaaaa tggataaaaa
    12001 aatgctatgt taagtgattt ttactgcaaa cgtcagttcc ttttttatct attaaatttt
    12061 tttaaaacaa ctaggtagca cccaagaagc tcatttttta aaagccacac gctaaagtca
    12121 attttgcatg tggctatttc tttatttagt gtgaaatctt tcaaagagaa ctctttgggt
    12181 gctaatattg ttaagtgctt tgcaatctta agaaattttc agtggcaatt aatgagtgct
    12241 cctctaaaat cactatttct ttgattatat agaaaggcag cccatccctt gtctcaattc
    12301 atttagttat tcacacattt tttaattttt ttcacttcat ctatactgag ttttaccatt
    12361 tttgcaactt tttcaactga aaatccttcc cttaataact cggctgccaa attccttttt
    12421 tcttccattt tccctttttc aatccctatt tcaattcctt cttccttccc cttttcaatc
    12481 cctttttcaa tccctttttc tatccctatt tcaattcctt cttctttcac agttttcaga
    12541 tactctgcaa atgtaggagc ttctttaagc tcttcagaat acagcatatg gtttgcctcc
    12601 ttttcaatgt gaataaataa ctctttcgtt aattgttttg ttaactcacc aggaagatac
    12661 agaagatagt caataaagta acaaagcgct tccgcataat tagaactaag attttggttg
    12721 gataagatga attcttttaa caattttttc ttaacttcat atcgtttctg atagttcttt
    12781 tccgttagat gaaggtaaat acccgccaat actgcaatgg caaaagggtt cgtagacttt
    12841 ttcaaagaag gaatgtccgc ttcattaaac ttataagtgt taaagcgata cgtaagttca
    12901 gtgccgtaaa aggagtattg gaacggctct gagttatttg atttagacaa atcggtcaaa
    12961 atcgcaatgg aataaatgtt ttcttggaag cgatcaaaca agcgataaaa ataagtaaac
    13021 attcgtttgg aaaagtccgg atcttgtttt tcttgaattt caatgtgaat gaatacatat
    13081 ttttcttcgc cgtttttcaa ggaaaccttt acaattttgt ctgcaattct tttccctttt
    13141 ttatgcttga tgatgacttt gtgcagttcc tgttcgagaa aaacaattcc ttttccaaaa
    13201 tcaatggtct catacaaatc aggtgcaaag aataaaataa attcctcaaa cagttcactt
    13261 ataattttct tccaaagccc gtcgtaatca gttccgggta aatagtttac ctttttctcc
    13321 agaataagta cttctcccat tattttaccc catcctttgc taaaattgaa ttattaatca
    13381 tattatacat gataagaacg tttgtttcca caaaattttt cgaccactat attgtgctcc
    13441 accaggtttt atccataggc cgaatgaaga acaccggaag cgattaaacg cacactaccc
    13501 aaagtggtat ggcaatttag gcagtggaag cttttttcaa ggaacggagc tgaacaactt
    13561 cgaaagggcc aacattgcca gcagctccac ccaccaatcc ggcatggtcg gaaagaaaat
    13621 ttccaaaacg atctggatat cccggtggaa gtggaatacg cgacgacttc cgcgacttcc
    13681 aacaaccctc tctgttatat caaatcattc agttcattca ttttttgact ttgaggcgat
    13741 gggccggaag agtttaaaaa ccgtttcaac gcactttgat ttttcaaaca aaagtactga
    13801 ctgcattcct ttcaaaacag aaaattgtta aaataatgat gggaatgcac tttcagaagg
    13861 agctggtcca gaattgtcaa aaatcatgat tgtggaagac gatgtgaaaa ttgcacgggt
    13921 gctggagctc gaattgcagc atgagcacta tgataccgtt tgggtagaga acggatcaca
    13981 agcactcaac ctgctagaaa gcgaagattg ggatttggta ctgctggatg tgatgatccc
    14041 ctgcttgagc ggtctcgagg ttttgcggcg ctaccgtatg agaaacagcc ggacaccggt
    14101 cattttgctg acagcccgca attctgtcct cgataaggtg aacgggctag accatggtgc
    14161 aaatgactat attacaaagc ctttcaatat tgaggaattg ctcgcgcgga tccgtgccgc
    14221 gctgagaacg ggtgcactcc ataccggcaa atccgaaaac agcaagaaac acgaatatgc
    14281 ccttgccgat ttgcttgtca acacggcaac aaggcaggtg acaagaggcg gcaaaccgat
    14341 tgaattgaca aaacgggaat ttgatctttt atgctatttg ttaaagaata aacgcattgt
    14401 attaaaccga gaacagttgt taaatgaagt atggggattt gaatatgcgg gagatacgaa
    14461 tgttgtagat gtttatattg gctatttgcg caaaaaaatt gaccacgggc acgaaacagc
    14521 gctgatccac acagtgaggg gcgttggtta tacaatgaag gagacgggtt aatgtcgatt
    14581 aagaaaaaac tttcggcatt gcttattctc tggtctttta ttgtgctctt tgccggcaat
    14641 accattgtat ttttggcgtt tctttatttt tcaaaagacc ggttggaaac aagcctggag
    14701 aacagtgctg aacaattagc tgaaagtgtg ggcagcgggg atgcgctttt ttccgatccg
    14761 gaaccgatat tgcaaacgca tgtaccggat gaagggatga tccgtttatt taatgcacag
    14821 caccaaaaga tttatgtaaa agcggatgaa gaggacctgt tgtccatcaa accggtgttt
    14881 ccgaaagatg accaaacccg tactgttaaa ggtgaggatt tcactgctat tgtggcctcc
    14941 tatccgatca tggaaaacgg aaaatacctt ggaatgttgg aactctccgt ggtccccgaa
    15001 gacatatttg aagacagccg actgctgctt acgatcttac tggcctcctc tgctgtttta
    15061 attgtgctgg ccgcatttgt aggtgtaaaa acttccggtc tgttcttaaa accggtctca
    15121 acgatgatga agacgatggc ggatattgaa gaaaacggcc gctttgaaaa gatcccgctt
    15181 gccctgaatc atcacgatga actgtaccaa atggcgctta cctttaatgc catgattgac
    15241 cggcttgagg ccatgtttaa aaagcaggag caatttatct atgacgcctc ccatgaactg
    15301 aaaacaccgc ttacggttat tgaaagctat gctgccat
//
