LOCUS       c00135_gnlPro..        12239 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MELMHNEA_147.
ACCESSION   c00135_gnlPro..
VERSION     c00135_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 04:11:59
            Original ID  :: gnl|Prokka|MELMHNEA_147
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12239
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12239
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3821:6356]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3822..6356
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..12239
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12239
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             116..430
                     /locus_tag="ctg135_1"
                     /transl_table=11
                     /translation="MKRCKNWVVTIVAFLMLVGEISVLPANLQGSTSVVNAAIHHRRRK
                     HQYRDKTKIYTSNYRIVDNKRSKIFHVMRGHNYRMNRENAVFFKSKAAARAAGYRESKR
                     "
     CDS             complement(471..2771)
                     /locus_tag="ctg135_2"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNAKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGKVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNRYIITINFIN"
     CDS             2900..3748
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     75.6; E-value: 7.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg135_3"
                     /sec_met_domain="LysR_substrate (E-value: 1.6e-29,
                     bitscore: 92.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.8e-24, bitscore: 75.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDVGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQPKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIAA
                     I"
     CDS             3822..5051
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg135_4"
                     /sec_met_domain="Amidinotransf (E-value: 2.2e-109,
                     bitscore: 355.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQ
                     LLLNYLQELLTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQ
                     QAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELV
                     LNNHVLAVGISQRTSATAITDLAHNLFDHSSYDTILAIKIPHNHAMMHLDTVFTMINYN
                     QFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDP
                     IAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRC
                     MSCPLIREDL"
     CDS             5062..5493
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg135_5"
                     /sec_met_domain="OTCace_N (E-value: 4.9e-38, bitscore:
                     120.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWKWVMAAIMLPTVF"
     CDS             5454..6356
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg135_6"
                     /sec_met_domain="OTCace (E-value: 4.9e-47, bitscore: 149.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 2.3e-20, bitscore:
                     63.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGDGRDNVADSLLVCGSMLGVNVHIVTPKPLFTHPDVQKIAQNFA
                     QDSGSKNLITDDIAQGVKGANVVYTDVWVSMGENDWSERIKLLKPYTVTMKMMQMTGTP
                     DDQLIFMHCLTAFHDRTTQVGEEIYEKYGLNEMEVTDEVFNSKYAWQFTEAENRLHSIK
                     AVMAATLGNLFIPIACGGGGILVIVKDGHLRGVAGVIHKDFSAAKMAEDINADELVILT
                     TVDHAFLNYGKENQQAIGKIKVEQLKQYLAAGYFAAGSMKPKIEAAIEFVEKTGNLAII
                     TSLSNANKLADGVGTIIYN"
     CDS             6370..6906
                     /locus_tag="ctg135_7"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDINMNI
                     PGPIKNNRYLTKMFMLGINELENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFENQISLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPAKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             6986..8188
                     /locus_tag="ctg135_8"
                     /transl_table=11
                     /translation="MNKFIDVRIGISMELKKNKNNLKQITALIQYAFLKNNDLTKDENF
                     MSRYDHSTGYGYFDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASYPEYRGQGHISQL
                     MKEILHDLHRQDIPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIV
                     RGKWDNLAVQNGVIQLYERQLHTDDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERP
                     ISYLIYRIRDNTFLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPE
                     QNELQVDLRPYMMSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRK
                     VAVERKEDALVDFSGSITAWTQVLLGRLTMNAAVKLGLITDYRIKKLDFVKGDVSFYDY
                     F"
     CDS             8204..8365
                     /locus_tag="ctg135_9"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             8367..8972
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg135_10"
                     /sec_met_domain="LysR_substrate (E-value: 1.5e-12,
                     bitscore: 37.3, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHDGAFA
                     KLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDMTCFI
                     VAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAALLVASRSGYFILNENTARLINTTDL
                     QPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             9028..9138
                     /locus_tag="ctg135_11"
                     /transl_table=11
                     /translation="MKADSYILHSGDDFYAKKNFVTFNINGTCFRINWFG"
     CDS             9104..9610
                     /locus_tag="ctg135_12"
                     /transl_table=11
                     /translation="MVLVLGLTGLASQVETVDASTYGNGVQVTIPKKMQGTWYSYDRNA
                     HNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWMSGKTTKMKNDT
                     FYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKLAKKMKDYKFKK
                     VNYTL"
     CDS             9676..10368
                     /locus_tag="ctg135_13"
                     /transl_table=11
                     /translation="MTKLILGGEVMKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTS
                     QENEPGTLFMQTSHDEETTNFVVECYQDEASYDTHANSKQFKDFTDVAKDILTSRVKVE
                     LFPEFISTKAEKLAVTGSNDYVIYLTEIGVSLGKGDEFAHAVMKEMKTAVEEEKDILAM
                     IAGTVADQPNEWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKLQPDVIVD
                     QGAIFYQP"
     CDS             complement(10466..10594)
                     /locus_tag="ctg135_14"
                     /transl_table=11
                     /translation="MKGMRTLIKLLLIGGSFLTLGLMAISSVLINKPAVAKVKHRH"
     CDS             10938..11978
                     /locus_tag="ctg135_15"
                     /transl_table=11
                     /translation="MPGIVEQTLLEQQNIDLNEMVTMNQMIDQLLPNASKELQQKLKIK
                     IYNFVRTRKQPSITVRRRKYFKPAVAKLIIGNVQDYADAIERRAKEAPAKEDATDKRPA
                     SKSKRVKTITKRKILAKVIKNDKIDKSIQKKLEDKIASIVKTNFIKPVNKRGSFSVEDG
                     EKVIAELSPFYQNIKIDQKYRKNAEKAAENKETETKEKPEQHSKDQNESREGQSKDFER
                     KNNQKNSNNRNNNNQTQNQRKRQNKHPFEIRRENNNRSRNNQSNRRYNNRNNYDNRNNY
                     EFDEASGLRERYNTVIRNYNQLEQRYNALQDKYNQALDDKARLIEEMGKKNEDLRRVLI
                     DVLRKM"
ORIGIN
        1 gaactattta cacaaaagat ttgacagttt caaactagtt tctaataaac gtaggaacac
       61 ttcatatata aacgtatact atataaatat agtgacatat taagggagtg tttttatgaa
      121 aagatgcaag aattgggttg tgactattgt tgcatttctg atgttagtgg gagaaatcag
      181 tgttctgcct gcaaatttgc aggggtcgac atcagttgtt aatgcagcta ttcatcacag
      241 aaggagaaag catcaatatc gtgataaaac taagatttat accagtaatt acagaattgt
      301 tgataataaa cgatcaaaaa tctttcacgt aatgcgcggt cataattatc gaatgaatcg
      361 tgaaaatgca gttttcttca agagtaaagc agcagcacgt gcagcaggat atcgtgaatc
      421 aaaaagataa attaaaagac ttctaagagt tcaaagttcc tagaagtctt ttaatttata
      481 aaatttatgg taataatata cctgtttttc atcacaggtt ggtaaattaa gtcgattatt
      541 atggcagcaa taatcgctac aattacagta attgctaagt tttgaatgga aatctggacc
      601 attgcccaac cacaaagagc taagataaag gtcaatagaa catctgcaat ttgaacacta
      661 ccaaccaact tggatgggta atcttgccaa aagtacttac gagttctagt aatcaaaaca
      721 atcaacattg cgctaagaac taggtatacg taaaccatag tagaaacagc accgtgactc
      781 caaccgtgtg tgtttaagaa ccaaacaaac ccaataccaa ttaaagtcca accagcagct
      841 agtgaaaagg cgatcttagc aagcttagcc atattccagt tttctggctt ataagtaatg
      901 tgagtcctgt cagttccaat catcatcgta accatattgt tcataatggt atagataacc
      961 attgcattca aggccattgg gatgtagtca aagaaaagat agccaaaagt taacagcatc
     1021 gttaattcag cagttctagc aagcttggtt agtgaccaag tagtcattct ttggtatacg
     1081 cgatgtccag cgtctaaaat tttaacaatt gagcctagac catcgtctag taataccatt
     1141 ttacccgaac gcttagctac gtcagcagca tttgaaactg cgattcctac ttcagcttgt
     1201 tttaatgcag gcgcgtcgtt aactccgtca cctgtcatcc ctacgatata gcctttttct
     1261 tggaaaagct ttaccatctt gagtttatct tctggtaaaa catcagcaat accggccaaa
     1321 tcattaatat cagtattttc attgaaatcg tgaatcgaaa ttactttacc agttaaatca
     1381 acttgttctg ccactgcagc agcggtcttt tgattgtcac cagttaacat aattgggcga
     1441 acgccacgtt tcttgagttc agccaaagct gctttagagt ctgttctaac tttatcttgt
     1501 aagatgaaga caccagctaa cttatcgtca atcaagactg ccactgagcg tcctgccttg
     1561 aaattaattc cagaaatttc ttcatcggca tgtttatcga tcaaagataa ttgcttaaat
     1621 gaaccaagct ttgcattatg tccagcaaca tcagccatag aataaccagt gtcagaagta
     1681 aatggagtaa agttttcagc attcatgact ggaatgttat tttctactaa gtattcatcg
     1741 attgctgtat cgataatacc agcattacgt ttatcagttg cggctccagc taaagcaagc
     1801 acgtctttgt caggcaagtc acttagatca gtccaagcgg ctacggcagt tttgttttcc
     1861 gtaattgttc cagtcttatc aagtaaaagc aagttcaagt tagctgcgtc ctgaattcca
     1921 gttaggtcag aagtcaggac tccttcttta cttaagcggg ttgcttcaaa tgagttggat
     1981 aaagcaaaag ttgatggcat tgctacagga attgaagcaa taaacatcat tgccaggaat
     2041 ggcaacatat taataaaggt attgaaatta ccgcctttga agaaggaggc gataataata
     2101 actaaggtta aaacaccatc tagtaagcaa aggtagtaga taatcttagt caaaagttgt
     2161 tgtaagtgac caggagcagc ggaattgttg atcaaattaa tcgtcttacc gcttctagaa
     2221 tctttacctg tagcagtaac aacagctagg ccatcacctt caacaactgt agtaccggca
     2281 aaggcggtgt catcaattgc tttcttaact ggtttagatt cacctgtaat tgagctttca
     2341 tcacaagcta agttaccgtc aacaatttta acatctgctg cgagtacgtc cccgcgttta
     2401 agtgagatta aatcgccttt aactagttgt ttagaatcaa gtttgatcca cttgccatcg
     2461 cgttcaactg atacagtagg agtcaacttg tgtgaaatat tatttaaaac tcgtcttgat
     2521 tgctttttct tagatgcacc gttaaatgca gcaaataaaa gcatcaacaa cacgaataat
     2581 gattggaccc atttgcccaa gatacattct agaattaaag cagcttctag aatccaagcg
     2641 gataggttcc ataacttaga caagaactct ttaaagaaat tgtattcagg ctctggtact
     2701 tcatttaagc catcttcttt taagcgcttg tctgcttcgg cttgagttaa gccgtgaaat
     2761 ttatcagaca ttattttccc tccaaatcta ccttaataag gtagcacaga tattgctatg
     2821 aataaaatac taaaatacaa tataagatat taaatatttt aatatcacta tcaattgaaa
     2881 taaaaaaagg ataaataata tgaatctaaa acagttacgt tattttctag ttgtagcaga
     2941 agaaaagcag attacagcag ctgctaagcg cttgtatatt gcacagccac cattaagcta
     3001 tcaattaaaa caattagaga aagagttggg cgcgcaatta tttaaaagaa cggcacatgg
     3061 tattgagcta actgatgtgg gacaaatttt tcaaagctat gccaatgaaa ttatttctct
     3121 agctcaaaat gctgaaaacc aagtacataa gactatttcc ggtgaattgg gaacgattgc
     3181 aattggaatg gcatcttcct caacgggctt gataccaatg aattctttta atgaattacg
     3241 aaaatattat ccggaaattt cttttgatat ttatgaagat aatacttatg gcatcctgga
     3301 taaattagaa aaaaagacaa tcgatctagg cattgtacga acgccttaca accagacagg
     3361 tttaaatact aagactttaa caactgaaaa aatgatggct attagtgtag acccagattt
     3421 tcagccaaaa aaagaattac gcattaaaga tctagcagat cagccattga ttatttatcg
     3481 tcgctttgag gatattttta atcaaacttt tgcacatcat gggcttaaac cattttatgc
     3541 ggttaagtgt gatgattcac ggacagcaat tacttgggcc aagagaaaaa tgggagtagc
     3601 gctagtacca gaatcaattg cgacaactta tgcccaagaa aatatgatcg caattaaaca
     3661 tgctaattgg ataacacatt tgcagctggt ttggcgtaaa gatcatcaag ttacaccttt
     3721 aatgaaaaaa atcattgctg caatatgata atactgtaac ttttacctaa ttgatccata
     3781 ataaatgtaa acgggtacaa taattaatag aaggtggttg aatgtcgagt ccgattcatg
     3841 tttattcaga aattggtaag ttaaaaacgg tgatgttaca tcgaccggga aaagaactag
     3901 aaaatctagc cccagatatt ttgcatcgaa tgttgattga cgatattcct tatctgaaga
     3961 ttgcccaaga agaacatgat gcttttgcgc atgtattgag gcagcagggg atcaaagtat
     4021 tatatcttga ggatttatta gcagaatctt taacagatga gaaagttcgt cgggcattct
     4081 tagatcagtt actggatgaa tcaagtatta aaaaacagga tcctttgcat caattattgc
     4141 tgaactatct ccaagaattg ctaactaagg aaatggtaaa aacggtgatt gctggaatta
     4201 gaaaaagtgc gattcataat tctaccccat ctttagcaga tttggctgag gacccagatt
     4261 acccttttta tcttgatcca atgccaaatg tatattttac tcgagatcaa caggctgcaa
     4321 ttggttcagg gatgaccatt aaccggatga ctttcagagc tagacgacgt gaatcattat
     4381 ttatggaaac aattttgaaa aatcatcctg atttcaagaa cgcaactatt ccagtttggc
     4441 gtgaccgtta tcatcatggt cgccttgagg gcggggatga actagttcta aataaccatg
     4501 tgttagctgt aggtatttca caacgcactt ctgcaactgc aattactgac ttagctcata
     4561 atttatttga tcattcaagt tatgatacga ttttagcgat taagattccg cacaatcatg
     4621 ctatgatgca ccttgataca gtttttacaa tgattaatta taatcaattt acggttcatc
     4681 cctttatttt agataaagcc ggcaaaattg atatttatgt tctacagccc gatgatcaca
     4741 acggtgtaaa aatcacagaa aagaatgatt tggtgcaggt tttgaaagaa aacttacatt
     4801 taagcgaatt ggatttaatt ccaactggtg gtggtgatcc aattgccgca ccacgtgaac
     4861 aatggaatga cggctcaaat accttggcaa ttgcaccagg tgaagtcgtt acttatgatc
     4921 gtaattatgt atccaatgat ttgctaagaa aacatggcat catcgttcat gagattcggt
     4981 ctagtgaact ctcacgtggt cgtggcggtc ctagatgtat gtcgtgtccg ttgattcgtg
     5041 aagatttata agaggcaaaa aatgaaatat ttacaaaatg tttttcaagg tagaagtttt
     5101 ctcgattgta aagactatac tccagctgaa atttcatatt taattgattt tgcattacat
     5161 ttaaaagaac ttaaaaaaga gcatatccca catgaatatc tgaaaggtaa aaatattgca
     5221 ctactttttg aaaaagcctc aactaggacg cgatctgctt ttgtagtagc ttgtaatgat
     5281 ttaggtgctc atccagaata tctaggcgca agcgagatcc acttaggtaa aaaagaaagc
     5341 gtcaaggata cggctaaagt cctaggctca atgtatgatg gaattgaata tcgcggtttt
     5401 gctcaagaag atgtagaaga gctggctaaa tattctggcg ttcctgtttg gaagtgggtg
     5461 atggccgcga taatgttgcc gacagtcttt tagtttgtgg ctcaatgtta ggtgttaatg
     5521 tacatattgt tacacccaag cctttgttta cacatcctga tgtacaaaaa attgctcaaa
     5581 attttgccca agattcaggt tcaaaaaatt tgatcacaga tgatattgct caaggcgtta
     5641 aaggagccaa tgttgtttat accgatgttt gggtttcgat gggtgaaaat gattggtctg
     5701 aacgaattaa attattaaag ccatatacgg tcacaatgaa aatgatgcaa atgactggta
     5761 caccagatga ccaattgatc tttatgcatt gtttgacagc ttttcatgat cgaacaactc
     5821 aggtgggaga agaaatctat gaaaaatatg gcttaaatga gatggaagta actgatgagg
     5881 tctttaattc aaagtatgct tggcaattta cagaagctga aaatcgattg cattcaatta
     5941 aagcagtgat ggcggctact ttaggaaatt tatttattcc gattgcctgt ggcggtggtg
     6001 gcatccttgt tattgtgaaa gatgggcatc tcagaggtgt tgccggcgta attcataaag
     6061 atttttccgc tgctaaaatg gcagaagata tcaacgctga tgaattagta attctaacaa
     6121 cggtggatca tgcatttttg aattatggca aagaaaatca acaagcaatt ggtaaaataa
     6181 aagttgaaca gctcaaacaa tatctagcag caggttattt cgcagctggg agtatgaagc
     6241 ctaagataga agctgcaatt gaatttgtag aaaaaacagg taatttagca attatcacct
     6301 ctttgagcaa tgccaacaaa ctagcagacg gagtcggcac aatcatttat aattaactgg
     6361 gtgataaaaa tgaatatttt taatgaagga aaaaagcagg atattgccca agttttagca
     6421 gctaaagata ggcgagtagc tgtacaacat aagattttta ataagtatcc taatcaaact
     6481 ctagtcgaca ttaatatgaa tatcccagga ccaatcaaga ataatcgcta tttaactaaa
     6541 atgtttatgt tgggtatcaa tgagctggaa aatgcttgga ctaacctagg ttatcatttt
     6601 aaattggtga cacagcttaa tgatgatagt ggctgtgaaa acttttatgt attatctttg
     6661 tcaattgaaa aagtaaagcg ctcaacaatt gattttgaga atcagatatc attgggacgt
     6721 ctctttgatg cagacgtgtt ggtaaaaaat aaacaagctg caatttcacg cagagatttg
     6781 ggcaggcagc cacgtaagtg ctttttatgt gatcgccctg ctaaagaatg tgctcgcagc
     6841 cggagacatt cagtggaaca gatgcaggca tttatctctc agctttatca agaatacgtt
     6901 gcgtaaaata aaccgggatt ttatgattcc ggtttatttt tatgaaaaat ctagttaaaa
     6961 atttaaaaaa tgaactaaaa tagtaatgaa taaatttata gatgtacgta taggaataag
     7021 catggaatta aagaaaaata agaataattt aaagcaaatt acggcattaa ttcaatatgc
     7081 atttttgaaa aataatgatt tgactaaaga cgaaaatttt atgagtcgtt atgatcatag
     7141 tacaggttat ggctattttg ataaggaaaa attagctagc tatattatgg ttaatcgatt
     7201 taaaagtgat gtttttgggc atcatttacc gatggctgga ataggttatg tagcttcata
     7261 tcctgagtat cgtggccaag gtcatatttc ccaattaatg aaagaaattt tgcatgactt
     7321 acataggcaa gatattccgt ttgctaacct ggcaccattt tcggagagct tttatcgcca
     7381 gtacgggttt agcaatagta tttatcaaaa agaatatcgc tttgatggaa gcgcattgcg
     7441 tagttttaaa ttaccacgtt ctggtcatat agtgcgtggc aagtgggaca atttagctgt
     7501 tcaaaatggt gtgattcaac tttatgaacg tcaactgcat actgatgatg aacgtaacac
     7561 ggttgtacgt gaggcatggt ggtggaatag acttgattct tattatcatc accgcaatgt
     7621 agccgtttat tttgacgcgg atgagcggcc aattagttac ttgatttatc gcattagaga
     7681 caatactttt ttagctgatg aaatgtacgc aattacgccg cagggattac tgagtatgtt
     7741 tggttttatg ggttcgcacg cgggcagtgt taagcaattt aaaatgagcg taccagagaa
     7801 atcgttacga gctgaacttt ttcctgaaca aaacgaactc caagttgatt tgcgtcctta
     7861 tatgatgagt cgaattattg attttgaaaa agttttggct tgtatgcggc caatgcaaga
     7921 aggtgatttt aatctggaag tcaatagcga tgaacagtgt ccttggaata ttggagtttg
     7981 gcaattaagt aatcatggac gtaaggtagc ggtagaacgt aaggaagatg cattggttga
     8041 tttttcggga tcaattaccg cgtggaccca ggtgctatta ggtagactaa ccatgaatgc
     8101 tgctgttaaa ctaggattaa ttacagatta ccgcatcaaa aaattagatt tcgttaaagg
     8161 cgatgtatca ttttatgatt atttttagtt gtgaggttaa aaaatgagta aagaaaagaa
     8221 actcaattta ataaaattat ttggcattgt agttagtggt ttgaatttga tcttttttgc
     8281 cttgatggca cttaataagc atgaagatac taaggataaa agaagagtag cagaagaagg
     8341 acacgcaccg ctggatgaaa aataaaatga cggaattaaa gattgcatat tttgaccaat
     8401 taggtcgtaa ggaattagat caggcagtgc agcattttgt gttaaaacat cctaatgtag
     8461 atgtaaaact acttgcgact agtcatgatg gtgcttttgc aaaactgaat gaagatgaag
     8521 cagacatagc aatcaatgat ttgcgtgacg agaatcttaa ctttgatgaa acagaattga
     8581 ctcaagctgg tgtaatggca attttgccca agggaatgta tcctaatggc attcaaatga
     8641 ttgaaaaaga cgagctcaat gatatgactt gttttattgt ggctaaacct gaagaagagg
     8701 ttagtgagct acatttattt aaagatttgt atcaaattgg cagtcaattc atcgcttcta
     8761 actcggtcga agaagcagca ctgttggtcg cctctaggtc tggctatttt attttaaatg
     8821 agaatacggc taggttaatt aatactacag atttgcagcc acttttcttg cttgatcatg
     8881 gtcagttaat aaagcaaaag ataatggctt tttataagtc aaattcagcg ttaagtagtg
     8941 agtttataaa gctattgcag caagaatatt aatctgtaaa gttaaaaata tcttgtctaa
     9001 gtactataag atactgtaaa atatattatg aaagcggact catatatttt acattctgga
     9061 gatgattttt atgctaaaaa gaactttgtt acctttaaca tcaatggtac ttgttttagg
     9121 attaactggt ttggctagtc aagttgagac tgttgatgct tcaacttatg gtaatggtgt
     9181 acaggttact attccaaaaa agatgcaggg tacttggtac tcttatgatc gtaatgcaca
     9241 taatggcaca aagatcacct ttactgaaca tactgttaat ggcaaaccaa tatttaccca
     9301 ggaggcttcg acaattagtg attacttcaa tggtagaatt gctaaccaga agaactttga
     9361 taaggtaacg caaaactgga tgtctggtaa aactaccaaa atgaagaatg atacattcta
     9421 tgagattgat ccgtggatta cttttgaaaa ttggagtctt tatcgagtgg taccacaaac
     9481 cattaatggt aaaaagcata acgtgctggt ttattctagt agatatgatg gtggtaacta
     9541 cttcagaagc aagaaattag ctaaaaaaat gaaggactac aagtttaaga aagttaatta
     9601 cacgttatag ttttgtgaca tcccttaact aagggatgtt ttttactaat agacgcgata
     9661 aaatttagta taataatgac aaaattaatt cttggaggag aagttatgaa attaaaacaa
     9721 acaccaattt tgcgtttata taaactagaa actaataaag aggatcatgc aaagttcgtt
     9781 aaggcagggc aacataatat gcttacttct caagaaaacg aaccaggcac attgtttatg
     9841 cagacaagtc atgacgaaga aactactaat tttgtagtag aatgctatca agacgaagca
     9901 agttatgata ctcatgctaa ttcaaagcaa tttaaggatt ttactgacgt tgctaaagat
     9961 attttaacta gtcgagtaaa ggtagaattg tttccggaat ttatttctac aaaggcagaa
    10021 aaactagcag ttaccggatc aaatgattat gttatttatc tgactgaaat tggtgtttct
    10081 ttaggtaagg gcgatgagtt tgctcatgct gtaatgaaag aaatgaaaac ggcagtcgaa
    10141 gaagaaaaag atattttggc aatgattgca ggaactgttg ccgatcaacc aaatgaatgg
    10201 ttagctattg aagtttatcg taataatgaa gcttacaagc agcacttgga aactaagaac
    10261 ttcaaagagt atttgaataa tacaaaatat tgtgttgaaa gtaagagttt acgtaagttg
    10321 caaccagatg taattgttga ccaaggtgca attttctacc aaccataaag aataagacga
    10381 aaagaagacc aggctatgtg gagtacataa cctggtcttt ctagttagag gggaaaagat
    10441 ttattaacat atattattct ggtttttagt ggcgatgttt tacctttgct actgctggtt
    10501 tattaattaa tactgagctg atggccatta aaccaagcgt taaaaatgat ccaccaatta
    10561 agagtagttt aatcaaggtt ctcattcctt tcatcttaat tgatcttata atagcgaaat
    10621 aatattaaga atttatatgt aaaacctaat ggattagtta agaaaataaa actagaaaaa
    10681 aggctggtta gcacgtaaaa tagaaataga gtcaaagtct agtgcaactg cgcataaaat
    10741 aaagcagtat cgatgggatg ctgcttgttt tggttaaaaa atagagaata tgcttgtagc
    10801 ccttttcgta aatagcgtta atgttgtaaa atggaaagtg cattaagttt attaatgaga
    10861 aaattgatgt attattgcaa aataggccgt aatggccctt tttgttgtga aaaaattaaa
    10921 agaatatagg attggaaatg ccaggaatag tagagcaaac attattagaa caacaaaata
    10981 ttgatttaaa tgaaatggta acaatgaatc aaatgattga tcaattgttg cctaatgcaa
    11041 gtaaagaatt acaacaaaaa ctaaagatta aaatttataa ctttgtgcgt acacgtaaac
    11101 aaccaagtat tactgtgcga agaagaaaat attttaagcc ggctgttgct aaattaatta
    11161 ttggtaatgt acaagattac gcagatgcaa ttgaacgtcg tgctaaggaa gccccagcta
    11221 aagaggatgc tactgataag aggccagctt ctaaatctaa gcgggttaag acaattacta
    11281 agcgtaagat tttagctaaa gttataaaga atgataagat tgataaatct attcaaaaga
    11341 aattagagga taagattgct tcaattgtga agaccaactt tattaagcca gttaacaagc
    11401 ggggaagttt ttcggttgaa gatggtgaaa aagttatagc tgaacttagt cctttttatc
    11461 aaaatatcaa gattgatcaa aagtatcgca agaatgctga aaaagcggct gaaaataagg
    11521 aaacagaaac taaagaaaag cctgagcaac attctaagga tcagaatgaa agtcgtgaag
    11581 gtcaatctaa ggactttgag cgtaagaata atcagaagaa tagcaataat cgaaataata
    11641 ataatcaaac gcaaaatcaa cgtaagcgac aaaataagca tccttttgag atcagaagag
    11701 aaaataataa ccgctcacgt aataatcagt ctaaccgccg ctataataat cgaaataatt
    11761 atgataatcg gaataattat gaatttgatg aagctagcgg tttgcgtgaa cgctacaata
    11821 cagtaatcag aaattacaat caactggagc aaagatataa tgctttgcaa gataaatata
    11881 atcaggcttt agatgataaa gctagattga tcgaagaaat gggtaagaag aacgaagact
    11941 tacgtcgtgt attgatcgac gttttgcgaa aaatgtagtt tttggtaaac aaagagacta
    12001 gtagtcaatt tgaattgatt actagtctta ttttatgttt atgaaatatg atttagctta
    12061 aaaattaaaa aaatatgtgt aaaaaattat tttcgtgtag taagattaaa ggatgataaa
    12121 tatttttatt aatgattaat ggaggagaag tatgagttta aaagagctat ttaaaagcaa
    12181 tgtgtttcga ggaaactgtc aaatcttttg tgtaaataga tttttctcgt agattgatt
//
