LOCUS       c00022_gnlPro..        24639 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JEAABOBI_24.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 22:16:17
            Original ID  :: gnl|Prokka|JEAABOBI_24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 280924
            Orig. end    :: 305563
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24639
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[290924:295563]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14639
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24639
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24639
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             238..1752
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 271.3; E-value:
                     3.8e-83)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_219"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-82, bitscore:
                     271.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSSQKDIINDILSAMQCYPENEAFIIDDKHYTYAQLGEITASI
                     THSLSEIKDEKIGIVAENRIETYAAILAVLAGGKTYVILHPAYPEERNLKIAALAGLRT
                     LLCTSDTDRSAFGTGHFRIIDTDRLPGKAQSEQQSHSSNEERNAYIIFTSGSTGEPKGV
                     PITRANLNAFYRAYSLLDWNLDEHDRMLQMFELTFDVSVVSLLYPLTLGAAVYTVGHQD
                     VKHFKVFELLEKYQLTFATVTPSLLQLLSPYFDEINLPSLKYLGVSAEASQTELLERFR
                     KSVPNATFINLYGPTEATIYCTCYRIPASDKCKHYNGMVAIGKPFPGIRAIIADEEGNE
                     LPQGETGELWVSGRQVMKGYLDDPEKSALVLIHRPDGQIYYRTGDLCILDSDGDIIYCG
                     RKDYQVKIQGFRIELSEIEYTAQSFFKTPCSVAAVPLLCDGICNELHLAVETTECTQSA
                     LIEYLKEKLPKYMLPKQIHCISQFPVTNSNKTDRKKIAELIKEKKL"
     CDS             1767..2009
                     /locus_tag="ctg22_220"
                     /transl_table=11
                     /translation="MNREEVLKQLQSIFRDILKKDNVCIDESSTSKDVDGWDSLTHMQI
                     IAQIEKHFGVRFNFREVIKFKNVGDLCSALLTKME"
     CDS             2013..3395
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MBOAT"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_221"
                     /sec_met_domain="MBOAT (E-value: 3.2e-20, bitscore: 66.9,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFLSFNFLALFTLCFFLYYAVKGRARNLILLVTSCIFIGWYYLP
                     FLLTAVVVALFTFFWAQWMESRAKAGKKTKPVYIAGIIALIGGWLLLHGTVIDDIIFPL
                     GMSFYTFQAISYLTDVYWQEQRSERNWVDFLIYMLFFMKFLSGPIERGGDLLPQLKDPR
                     PFIYSNAVTGLKYILLGLIKKLLIANQISPQTDVMFHSIHDLSGVQLLMTCLLYPIELY
                     ADFSGYTDIAIGGAYMFGIKLSPNFNRPFAARSTADFWRCWHMSLSFWVRDYLYVPLTA
                     GTRNWGQWGIYFSLLITFLALGLWHGAGLTFAIYGLIQGVLICWEMKTAAFRNNLPQYI
                     GKYAADSLLIVRTYLLFALSLIFFRVQSLSDAWYFLRNISFEVHSSWKEMNIGIRDHNC
                     IVAGSALLLVLIYEYYASKYNLMETLERQPAWLRWSVYYLLVFALLMLGKFDTETFIYL
                     QF"
     CDS             3414..4454
                     /locus_tag="ctg22_222"
                     /transl_table=11
                     /translation="MLHHSSRISPKTRFCLKLLLLILPLIPIVVVYFMFDPYRVLHPYK
                     RFDDSPMLLNEAHVGWQNYLQNRDSIVYNSFILGNSCTMAFLTGEWEKYLDKNDHAVRF
                     YDNGESLGGVRQKLQLLDSVGAPLKNILIVLDKKSLDKNAPLSGNNHLFSAEAAGISQL
                     GFQLRFLQEFLYPDRMIPYIDYLIRHKYAPYMKGVINPGDPVREPYTNNFINPREKEIA
                     QDGEIYWSRHEKEFKKRTNAGMEELPVIFASQIQVLRSIKKICDKHHTNLKFIIGPDYY
                     QKKTSREDIKILKAILGDSAVWDFTGINEYTADIHHYYEPGHYRPLLGARLLKAIYQDQ
                     DTCHRQ"
     CDS             4559..4951
                     /locus_tag="ctg22_223"
                     /transl_table=11
                     /translation="MKKILLLLSVCISFSSCCTLFSSSKQDITFTGMNGTKIYEASTKQ
                     KIAEIKEDNSVTVQIKKKREDKQLVAKKEGYQTTPFVLESTFNNACLWNILFWPGFLVD
                     LGTQKMNKWDNTIINIEMEKENTENK"
     CDS             complement(5144..5773)
                     /locus_tag="ctg22_224"
                     /transl_table=11
                     /translation="MLSDGDFQYIPYLFISMLANLDRYKIVLASNSPRRKELMTGLGVD
                     YVVKTLPDVDESYPDTLQGEEIPLFIAREKAAAYQSMIGPEELLITADTIVWHEGKALG
                     KPVGRQDAIEMLRSLSGKSHQVITGVCLTTREWQKCFAAVTDVRFAILDEDEIAYYVDH
                     YQPMDKAGSYGVQEWIGFVGVESISGSYFNVMGLPIQKLYRELKQL"
     CDS             complement(5757..6278)
                     /locus_tag="ctg22_225"
                     /transl_table=11
                     /translation="MSTINYDLTRIKALVFDVDGVLSANVIPLHPSGEPMRTVNVKDGY
                     AIQLAVKKGLRIAIITGGRSDVVRKRFIGLGVSDLYFGSAVKIHDYRGFRDKHGLTDEE
                     ILYMGDDVPDMEVMRECGLPCCPKDAVPEVKAIARYISYADGGYGCGRDVVEQVLKAQG
                     QWLSDDAFGW"
     CDS             complement(6299..7090)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_226"
                     /sec_met_domain="F420_oxidored (E-value: 2.2e-12, bitscore:
                     41.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVLIGAGNLATNLAKALYRKGFRIVQVYSRTEESAR
                     ELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEGKREEALMVHTAGSIPM
                     NVWEGHVPHYGVFYPMQTFSKQREVDFKEIPFFIEASSTEDAAFLKAIASTLSNRVYDA
                     DSEQRKSLHLAAVFTCNFTNHMYALAAELLKKYNLPFDVMLPLIDETARKVHELEPKTA
                     QTGPAIRYDENVIGNHLRMLADDPAMQRLYELLSRSIHERQ"
     CDS             complement(7087..7419)
                     /locus_tag="ctg22_227"
                     /transl_table=11
                     /translation="VSAVKANNKDTYKATAVTLIVIGVLYLIDKLIHFSTLGIPWVMNK
                     DNLLLYTAVIFLFIKRDKSVGLVLLGLWLVLNIGLIVSLLGSMSGYLLPLALLIIGGIL
                     YLISTR"
     CDS             complement(7422..7919)
                     /locus_tag="ctg22_228"
                     /transl_table=11
                     /translation="MRKFTGEELSQEDVVALLKAALMAPTSKRSNSWQFIAVDDKKLLG
                     ELSHCKEQASAFIADAALAIVVTADPLASDVWIEDASIASIMIQLQAEDLGLGSCWVQV
                     RERYTATGMPSDEFVRGVLDIPLQLQVLSVIAIGHKGMERKPFNEDHLQWEKIHINKFG
                     GK"
     CDS             complement(8125..8667)
                     /locus_tag="ctg22_229"
                     /transl_table=11
                     /translation="MLEEILEFNKKFVENRGYEKYITNKYPDKKIAILSCMDTRLTELL
                     PAALGIHNGDVKIIKNAGAVISHPFGSVIRSLLVAIIELGVEEVMVIAHSDCGACHMNS
                     DEMITHMKKRGIKSETIDMIRYCGVDFNSWLGGFDDPVKSVRGTVRSIENHPLIPKDVR
                     VHGFIIDSLTGELTRVE"
     CDS             8785..9768
                     /locus_tag="ctg22_230"
                     /transl_table=11
                     /translation="MPLKLTTYYQGSEIPDFPGTNTFHSKELFQIYEETPGYTPLLIMA
                     SEDGKPVARLLAAIRKSIRMFPPAFIKRCEIYGTGEYLTAEADKERIFGEMLEHLTTEA
                     LRNSFLIEFRNLENAMFGYKYFRSNRYFPVNWLRVRNSLHGIENAEQRFSPSRIRQIKK
                     GLKNGAKVDEARTVEEIREFSNMLRHLYSSRIRKHFPNIIFFQHMDTRLIHSRQAKIFI
                     VRYKDKIIGGSACIYSGNDAYLWFSGGMRKTYALQYPGILAVWKALQDAHQNGFRHMEF
                     MDAGLPFKKHGYRDFVLRFGGKQSSTRRWFRFRWQWLNDLLIKIYV"
     CDS             10001..10405
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_231"
                     /sec_met_domain="Glyoxalase_4 (E-value: 6.1e-23, bitscore:
                     75.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDTKIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             10531..12084
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_232"
                     /sec_met_domain="CT_Btheta (E-value: 1.4e-289, bitscore:
                     954.6, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETGEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLHGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             12105..13019
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_233"
                     /sec_met_domain="OAD_gamma (E-value: 3.6e-15, bitscore:
                     50.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTIDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             13045..13476
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 69.7; E-value:
                     4.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_234"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.2e-21, bitscore:
                     69.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKPVTRPAAAPKTETGAPVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKRGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             13479..14639
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_235"
                     /sec_met_domain="OAD_beta (E-value: 1.1e-152, bitscore:
                     502.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             14788..16119
                     /locus_tag="ctg22_236"
                     /transl_table=11
                     /translation="MRTRTMKPLFLIFCLCLSPLLMGQNQNKIQEAMANYDYETAVELI
                     NKEPPTIPLLMQKAKALKGIGSNAEALRSIRQVIAEDSTNQQAHIEAAECCKAMAKYND
                     ALDYYRKAISLNPKNKYARLQFINLLCNTKNYAEAFGESSMMSETDSSAVVLHLQAQSL
                     EGMQQILPAIGCYEVIQDKYPDDYLAAAKLGNLNIVAGYPEYAIQATERYRERDSTNLI
                     VNQQNALAYCHAEQYPTAIKRYEKLCQQGDSSTQTLYYLGVSYYADEYYYEAHACFSKL
                     QKEMEENPNLLYYLGRCCAKTSWKKEGIEHLEKAIELTIPKDSTMIRLYKGLVDCCKLA
                     QDTPKQIQALRELYKYDKTNHKLLYDIAWNYSYQLKDNKSAERYLQAFLKTRKANARKE
                     EPVSEKGELVLGLENYYNAAENWLKDLQKEKFFKEGIPLESQKQ"
     CDS             16136..17428
                     /locus_tag="ctg22_237"
                     /transl_table=11
                     /translation="MKHWILLLYLGFSVVLQAQNTASVQEAMANYDYKTVIRLIDEESA
                     SPQLLIQKAKALKSLGRTAEALSTLQHIIIELPENQQALVEAAECCRQLSKFNEALGYY
                     RKVMELNPEHIYAHLQYTRLLYNYQRYGDALRESIALARKDSSATVLRLMAESMEGAGM
                     PVESMFCYLSIIRKYPSDYLSVAKLGSIFNTMKDYEGAIALTEAYRRTDSTNVEVNRQN
                     ALAYCLRKEYPTAIKRYQDLTARGDSTLLTCYYLGVSYYATKEYYKARDWLLKAKSCQS
                     PGANLLYYLGRSCSKTLWKQEGIGYLNQAIALTIPADSIMERLYSGLADCYRQTKQTRD
                     QIKATKEQYKYAPDKHILLYNLAFLSDKIGDTKATEHYLQAFLRTKSKQNAVLQQPDDD
                     EEEPAPYIDYYKSATNKLESIRKEKFLKGEK"
     CDS             17966..19816
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_238"
                     /sec_met_domain="Alpha-amylase (E-value: 1.6e-62, bitscore:
                     206.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLLLLLGSFLLSLTTYAAMNISKIDPPFWFTGMNNPELQLMVY
                     GEGIGQASVSVNYPGVSLSSVVKLESNNYLLVYLHLDKEVKPGKMPITFTVGKKKLVKE
                     YELKARSKAGVDHKGFDASDALYLLMPDRFANGNPDNDRIEGMAEYKVDRNDPNARHGG
                     DLAGIEQNLDYFTDLGVTALWFTPVLENNMKGGSYHGYATTDYYKVDPRFGTNEEYRSL
                     IAKAHNRGIKVVMDMIFNHCGVEHPWIKDMPSKDWFNHADFKNNFVQTSYKLTPHVDPY
                     ASEYDFDQMNNGWFVEAMPDLNQKNPHVYKYLLQNSLWWIEYADIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPRNSHLKTVMDFSFFDKV
                     NTAKNEQTDTWFKGLDRVYNNFVYDYLYPNPASVLAFIENHDTDRFLGEGENLDMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWTDDKENALTPEGRTRLQNE
                     SYNFYRNLLNWRKGNDVIAKGSMKQFMVQHGVYAYARQYKGKTVFVLLNGTDKEVKLPL
                     KYYAEVLKDKTQGKDVISGKVTALNEELTMAPRQSMVIEL"
     CDS             19974..20414
                     /locus_tag="ctg22_239"
                     /transl_table=11
                     /translation="MTNNESERELVLQTLRTWMAFRQAVQRVLKRHNVDMTFEMLQVMN
                     CLWNKQGISQQSLAEKTAKDKACLTNLINNLEKKNWVIRKEGPSDRRNRLIFLTPQGEE
                     LALTVKPLINDIYAQTGAEMEASRITECIEDLKRLHEVLNEI"
     CDS             20427..21494
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_240"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 6.2e-11,
                     bitscore: 36.2, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRQIKLKQLRRLKFRNIFLNTVCILLALAGISWTVNYFWKYAR
                     YEITNDAVVDQYIAPLNIRIPGYIKEVRFTEHQYVHAGDTLLILDDREYRIRLKDAEAA
                     LMDALGSKEVLNSGIRTSGVNVAVQEANIAETLAHLSQQEAELNRYTRLLKKQAVSQQD
                     YELAKANFEATRARYNALLRQKEAAQSQYSETSKRSTGAEANILRKEADLEMARLNLSY
                     TVVTAPYDGYTGRRTLEPGQFVQGGQTLSYLVRGNDKWVTANYKETQIAHIYIGQKVRI
                     KVDAFSGRTFHGTVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLNDASPEEME
                     CLRAGMMVETEAVRP"
     CDS             21499..23094
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_241"
                     /sec_met_domain="MFS_1 (E-value: 3.9e-13, bitscore: 43.1,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLNLPTRPWVPQWLGIVTMFIVIFPITLLNGAYTGSMVEVSNT
                     LGVLSEDITMAYYSASVGIAVAYPIVPKIRTIATPKTLLLTDLLLQIFFSLVCAKTGSM
                     DVIMVCSFCMGFLKAFVMLEFIILIRPLFSPKNVRSEFYAYFYPIVFSGGQLSMAITAQ
                     LAYHYQWQHMYYFVTILLLIAILFVICFFRYARRPMHIPFKEMDGRSMFIIATAFLLTL
                     YTFTYGKTLDWFASPKIRVYVFVIPLLIALFIHRQRTQGKPFVSLKPLFLHKSIIGYGF
                     MVLAMFLTATSSLVTNYMNSIIRVDSIHANSLSLWLLPGYVVGAVICFWWFRWQRWRFR
                     FLISGGMFCYVIYLAILYFGITPYGTYEMLYLPILFRGVGMMVIFIAFGVFVVEDLDPR
                     LTLSNAFFLISFRSVLAPVLSASFFNNMLYYLQAKGMNILSENMTLTNPLAEQKYNQAL
                     SNALAQGHEFGEAGQLAANSLYSTLQQQSLLLALKTLIGYVLILALVIAVIAAFIPFHK
                     TLKVAVVKTGDDMV"
     CDS             complement(23189..24193)
                     /locus_tag="ctg22_242"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKNPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYDENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTEPDEVVDFVTKTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFDVLDGV
                     MKELPGFPIVLHGSSSVPEEEVATINQFGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE"
ORIGIN
        1 gtatcaataa agtatcgtgt tgtctatccc attcaaagtc gtcggctatg aagccaacgc
       61 tatttcccct tccgaaagag ggaaagcgag accgggcacg tgcgtaccac acaattaaca
      121 ttctttaatc gattgtgcgt agggagatca gaccatttca ctgtcatctt aataaacgat
      181 ctcaagaaga tatataaaga acccctaaac ccaaaacatg aataaaaact aatggatatg
      241 acaacatctt cccagaagga tattatcaat gatattcttt ccgccatgca atgttatccc
      301 gaaaacgaag cattcattat tgacgataaa cattatactt atgcccaact cggtgaaata
      361 acagcttcta tcacccattc gctatcagaa ataaaagatg aaaaaatcgg aatcgtagcg
      421 gaaaaccgga ttgaaaccta tgctgctatt ctggcagtac tagccggcgg aaagacctat
      481 gttatcctgc atcctgccta cccggaagag cgtaatctca aaatagccgc tctggccgga
      541 ctgcgtactt tgctctgtac aagtgacact gaccggtcag cattcggcac cggacacttc
      601 agaatcatcg atacggaccg gctaccggga aaagcacagt cagaacaaca gtctcattca
      661 tcgaacgaag aaaggaacgc ttatatcatt tttacatcgg gaagcacagg cgagcccaaa
      721 ggagtgccca tcacacgggc taacttgaac gccttttacc gggcatacag tttgctcgac
      781 tggaatctgg atgaacatga tcgcatgttg caaatgttcg aacttacatt cgatgtatcc
      841 gtagtatcct tactgtatcc tcttacttta ggtgctgccg tttatacggt aggccatcag
      901 gatgtaaagc acttcaaggt gtttgaactt ctggagaagt atcaactgac ctttgccact
      961 gtcactccct cactgctaca actcctttca ccctacttcg atgaaatcaa tctgccctct
     1021 ctgaaatatc tgggagtatc ggcagaagca tcgcaaaccg agctgttgga gcgattcaga
     1081 aaatcggtac ccaacgcaac gttcatcaac ctatacggac cgaccgaggc tacgatttac
     1141 tgcacctgtt accgtattcc ggcttcggac aaatgcaagc attacaacgg aatggtggct
     1201 atcggaaaac catttcccgg catccgcgcc atcattgccg acgaagaagg aaacgagcta
     1261 cctcaaggag agacgggaga actttgggta tccggccggc aggtaatgaa aggttatctg
     1321 gacgacccgg aaaaatcggc attggttctg atacaccgtc ccgacggaca aatctattac
     1381 cggaccggag acttgtgtat tctggatagc gacggggata ttatttattg cggacgtaaa
     1441 gactatcagg tgaaaataca gggtttcagg atagaactga gtgaaataga atatactgcc
     1501 cagtcgtttt tcaagactcc ctgcagcgtg gctgccgttc cgttgctctg cgacggaatc
     1561 tgtaacgaat tacatctggc cgtcgagaca actgaatgta cccaaagcgc attgatagaa
     1621 tatctgaaag aaaagctgcc caaatacatg ctgccgaagc agattcattg tatttcccaa
     1681 tttccggtga ccaatagtaa taaaacagac cgtaaaaaga ttgccgaact gataaaagag
     1741 aagaaactct aaaaacaata ataaatatga atcgagaaga agtattaaaa caactacaaa
     1801 gcattttccg tgatatctta aaaaaggaca acgtatgtat cgacgaatca tctacctcaa
     1861 aagatgtaga tggctgggac tcgctgaccc acatgcaaat tatagctcaa atcgagaaac
     1921 atttcggagt acgtttcaat ttcagggagg tcattaagtt caagaatgtc ggcgatttgt
     1981 gcagtgcctt attaaccaaa atggaataaa cgatgcagtt cctctctttt aatttcctgg
     2041 ccctgtttac cctctgtttc ttcctctact atgcagtcaa aggccgtgcc cgcaacctta
     2101 tactactggt aaccagttgt attttcatcg gatggtacta tctgcctttc ctgttgacgg
     2161 cagtagtggt agcactgttc accttctttt gggcacaatg gatggaaagc agggcaaaag
     2221 ccggaaaaaa gaccaaaccc gtctatatcg caggaatcat cgccctgatc ggcggatggc
     2281 tccttcttca tggcacggtc atagatgata tcatctttcc actcgggatg tcattttaca
     2341 catttcaagc catcagttat ctgacagacg tgtactggca agagcaacgc agcgaaagaa
     2401 actgggtgga tttcctgatc tatatgcttt tcttcatgaa gtttctctcc ggccctatcg
     2461 aacggggtgg agacctgttg ccacaattga aagatccccg cccgttcatc tactcaaacg
     2521 cggtgaccgg actgaaatat attttactcg gactgatcaa gaaactgctg atagccaatc
     2581 agatctcccc acaaacagat gtcatgtttc attcgattca tgacctctcg ggtgtacaac
     2641 tgctaatgac ttgcctactc taccctatcg aactgtatgc cgatttttcg ggttatacgg
     2701 atattgctat cggaggggcc tatatgttcg gcatcaagtt gtctcctaac ttcaaccgcc
     2761 cgtttgcagc acgctcgact gccgacttct ggcgctgttg gcacatgtca ctctccttct
     2821 gggtacgcga ttatctctat gtaccgctaa ccgccggtac ccgtaactgg ggacagtggg
     2881 gaatctactt cagcctcctc atcacctttc tcgcattggg tttgtggcat ggggccggat
     2941 tgactttcgc catatacggc ctgattcagg gtgtccttat ctgctgggaa atgaaaacag
     3001 ctgctttccg caataatctg ccccaatata taggaaaata tgcggccgac agcttgctga
     3061 ttgtccggac ttatctattg ttcgcactct cgcttatatt ctttcgtgta caatcgctga
     3121 gcgatgcctg gtatttctta cggaacatct cgttcgaggt acattcttcc tggaaagaaa
     3181 tgaacatcgg catacgcgat cataattgca tcgtagcagg ttcggcccta ttactagtat
     3241 tgatctacga atattatgca tctaagtaca acctgatgga aacacttgaa cgccaacccg
     3301 catggttacg gtggagtgtc tactatctgt tggtattcgc tctgctgatg ttaggcaaat
     3361 ttgacacgga aactttcatc tatttacaat tttaaccgaa accctttacg cgcatgctac
     3421 atcattcatc gagaatctcc cccaagacac gtttttgcct gaagttgctt ttactgatcc
     3481 tgccgctgat cccgatagtg gttgtctatt ttatgtttga tccttatagg gtattacacc
     3541 cctacaaacg attcgatgac tctcccatgc tactcaacga agcccatgtg ggatggcaga
     3601 attatctgca gaatcgcgat tcgatagtct ataactcctt tatactcggc aactcctgta
     3661 ccatggcatt cctgacagga gaatgggaaa aatacctgga taagaacgac catgccgtac
     3721 gcttctatga caacggagaa agcctgggcg gcgtccgtca aaagcttcag ctgctcgact
     3781 ctgtaggtgc acccctgaaa aatatactga tcgttctgga taaaaaatca ctggacaaaa
     3841 acgctccttt atcgggcaac aatcatctgt tttcggccga agcagccggc atcagccaat
     3901 tgggattcca gttgagattc ctgcaggagt tcctttatcc ggacagaatg attccttaca
     3961 tagattatct aatccgacat aagtatgctc cttatatgaa aggggttata aatccgggag
     4021 atcccgtcag ggagccttac acgaacaatt ttatcaatcc cagagaaaaa gagatcgcgc
     4081 aagatggcga aatatactgg agccgtcatg aaaaagaatt caagaagcga acgaatgcgg
     4141 gtatggaaga acttcctgtt atatttgcca gccagattca ggtacttcgc tccatcaaaa
     4201 aaatctgcga taagcaccac acgaacctga agttcattat cggtccggat tactatcaga
     4261 aaaagaccag ccgggaagac ataaaaatat tgaaggctat actgggtgat tccgctgtct
     4321 gggatttcac gggaatcaac gaatacacag ccgacataca tcattattac gaacccggtc
     4381 attatcgtcc gctgctggga gcacgcttac tgaaagccat ttatcaggat caagacacct
     4441 gccacaggca ataaaagttc ctcccataac agtagcacac acagaagaag agcatcctcg
     4501 atccgaaaga aataattaga tcaaagaaaa caattatatc acattaaaaa cttagattat
     4561 gaaaaagatt ttattattgc tatccgtctg tatttcattt tcatcatgct gtacattatt
     4621 cagcagttcc aaacaagata tcacctttac gggaatgaat ggaactaaaa tctacgaagc
     4681 atcgaccaaa cagaaaatag cggaaatcaa agaagacaat agtgtcactg tacaaatcaa
     4741 aaagaaaagg gaagacaaac aactagtagc caaaaaggaa gggtaccaaa cgactccctt
     4801 tgtcctggaa tctacattta acaatgcctg cctgtggaac attctatttt ggccgggctt
     4861 tctggtagat ttgggtacgc aaaagatgaa caaatgggat aacacaatta tcaatatcga
     4921 aatggagaaa gaaaatacag aaaacaaatg atcaaactat aatttcgcat ggcactcttc
     4981 tccttccacg gagggagtcg ccatacggaa tcatgcgacc tacaaggaag gcataattca
     5041 ccacaaggca acacagagtt ttttataaaa gttctttaga gaataaatct actctgtgag
     5101 actctgtgct actccgttgt atatacgagt ttcggcacac tctctatagt tgtttcaatt
     5161 ctctgtataa tttctgaatg ggaagtccca ttacattgaa gtagctgccg gatatggatt
     5221 ctactccgac aaaaccgatc cactcctgca caccatacga accggctttg tccatgggct
     5281 gatagtgatc gacataataa gcgatttcat cttcatcaag aatcgcaaaa cggacatccg
     5341 tcacggcagc gaaacatttt tgccattctc gggtagtgag acacacaccg gtaatcactt
     5401 ggtgcgattt accggagagg ctccgcaaca tctctatggc atcctgcctt ccgacaggtt
     5461 tgccgagcgc tttgccttca tgccagacaa tggtatcggc tgtgatcaaa agctcttccg
     5521 gtccgatcat cgactgatag gcggctgcct tctcacgggc tatgaaaaga ggaatctctt
     5581 caccttgcaa cgtatcggga taagattcgt ccacatccgg caaagttttt actacataat
     5641 cgacacccaa gcccgtcatc agctctttcc gacgcggaga attagaggcc aatacgattt
     5701 tataacgatc taagttagca agcatactga taaataaata aggtatatac tggaaatcac
     5761 catccgaaag catcatcgga caaccattgg ccttgtgctt taagcacctg ctccaccaca
     5821 tcgcgtccac agccgtatcc tccatcggca tatgaaatgt aacgggcaat cgctttcacc
     5881 tcgggaaccg catctttggg acaacaaggc aatccgcact cacgcatcac ttccatatcg
     5941 ggaacgtcat cgcccatgta gagtatctcc tcgtccgtaa gtccgtgttt gtcacggaaa
     6001 ccacgataat cgtgtatctt caccgcagag ccgaagtaca gatcggatac ccccaacccg
     6061 ataaaacgtt tccgcacgac atcgctccgc ccacctgtaa taatagcgat acgaagccct
     6121 ttttttacgg ccaattggat ggcataaccg tcttttacat ttaccgtacg catcggttca
     6181 cccgacggat gcaaagggat gacattggcg ctcagcactc cgtctacatc aaaaacaagt
     6241 gcttttatcc gggtaaggtc gtaattgatt gtgctcattt ttatttaatg tttcgggatt
     6301 attgtctttc gtgaatgctt cggctaagca actcgtataa ccgctgcatg gcaggatcat
     6361 cggcaagcat ccgcaagtga ttgccgatca cattctcgtc ataacggatg gccggcccgg
     6421 tctgggccgt cttaggttcc agttcgtgca ccttacgggc ggtttcatca atcaacggca
     6481 acatcacgtc aaacggcaga ttgtatttct taagcaactc ggcagcaagg gcatacatgt
     6541 gattggtgaa attacatgta aacacggcag ccaagtggag acttttacgc tgctccgagt
     6601 cggcatcgta cacacggttg gacagtgtag aggcaatggc tttcagaaac gcggcatctt
     6661 ctgtcgaaga agcctctatg aagaaaggaa tctccttaaa atctacctcc cgctgcttgc
     6721 tgaaagtctg catgggatag aacacaccgt aatgcgggac atgtccttcc cagacattca
     6781 tcgggatgct acctgccgta tgcaccatca atgcctcttc ccgcttacct tcgacaatgc
     6841 cctgaagaag ttcggcaaag gcggaatctt tcagtgaaac aatatacagc ttcgcatacg
     6901 ggttcacctc tgcgaggtct gtcgtatatt cggcttccac tttctgtgcc agctcgcggg
     6961 ccgactcttc cgtacggcta tacacctgta cgatacgaaa tcctttccga tataaggctt
     7021 ttgccagatt agtggcaaga tttccggcac cgatcaatac gatcggcgta tcttctatac
     7081 ttcttttcat cgtgttgaaa tcaaatacaa tatacctccg attatcaata aagccaaagg
     7141 cagcagataa ccggacatcg aaccaagcaa cgaaacaatc aggccgatgt tcagcaccaa
     7201 ccacaatccg agcaatacca agccgacgga tttatcccgc ttaataaaca ggaaaatcac
     7261 cgcagtgtaa agcaaaagat tatccttatt catcacccaa ggtatcccca aagtggaaaa
     7321 gtgtatcagt ttgtcgatca gatagagcac ccctatcaca ataagggtga ctgccgtggc
     7381 tttgtaggta tctttattgt ttgcttttac tgcactcacc gttacttacc tccgaactta
     7441 ttaatatgga ttttttccca ttgcaaatgg tcttcattaa agggtttacg ttccatccct
     7501 ttatgcccga tcgctatgac ggacaacacc tgcaactgca aaggaatgtc gagcacaccg
     7561 cgcacaaatt catcggaagg catcccggtg gcagtatatc gctcacgcac ctgcacccag
     7621 caacttccca accccaagtc ttcggcctga agctgaatca taatagaggc aatggaagcg
     7681 tcctcaatcc atacatcgct cgccaaggga tcggcagtaa cgacaatggc caatgccgcg
     7741 tcggcaataa aggccgaagc ctgctctttg caatgtgaaa gttcaccgag caacttttta
     7801 tcatcgactg cgataaactg ccagctgtta ctgcgctttg aagtaggagc catcagggcc
     7861 gctttcagca aagcgactac atcttcctga gaaagttctt ctccggtaaa tttccgcatg
     7921 ctgcggcgat tttttattag ttcactgaaa ttttccatgt atctatactt tgcattattt
     7981 gaatataccg ccagtcacca tagaatgcac aaacacacgc gaaccaaggt accacccggc
     8041 atgcccgtct acataaggta tgccctgcag gactttgcat gaatcggcgc gctccgtggc
     8101 gattcgggcg caaagatagg caatttattc cactctcgtc aactcgccgg tcagtgaatc
     8161 gatgataaaa ccatgcaccc ggacatcttt cggaataagc ggatggttct ctatggaacg
     8221 aaccgtgccc ctgacggact tcaccggatc gtcgaatccg cccagccacg aattaaaatc
     8281 gaccccgcag tagcgtatca tgtcgattgt ttcggacttg attccccgct ttttcatgtg
     8341 agttatcatt tcgtcgctgt tcatgtggca agcaccgcaa tcggaatggg caatgaccat
     8401 cacttcttct actcccaact cgatgatggc caccagcaga ctacggatga cactgccgaa
     8461 aggatgggaa atgacggcac cggcattctt tataatcttt acgtctccat tgtgaatccc
     8521 caaagcggcg ggcaacagtt ctgtcagacg ggtatccata caggaaagga tagcgatttt
     8581 cttatcagga tacttgttag tgatatactt ttcgtatccc ctgttctcaa cgaacttttt
     8641 gttgaattca agaatttctt ctaacataat caaaaacgga ttttattgta gtatctccac
     8701 aaagatagtc acaaaacgac agctcaacaa aataagccct gcaaatgttg taaagagaaa
     8761 taaaaaatgt aaatttgtcc cgatatgcca ttaaaactga ctacatatta ccaagggagt
     8821 gagattccgg attttcccgg aaccaatacg tttcattcga aagagttatt tcagatctac
     8881 gaagaaactc cgggctacac cccactcctg attatggctt cggaagacgg aaaacccgtt
     8941 gcgcgactgc ttgctgccat ccgcaaaagc atccgcatgt ttcctcccgc tttcatcaaa
     9001 cgctgcgaaa tctatggcac gggcgaatat ctgacagcgg aagccgacaa ggaaaggata
     9061 ttcggcgaaa tgctggagca cctcaccacg gaggctttgc ggaactcgtt tctgatagaa
     9121 ttccgcaatc tggagaacgc catgttcggc tacaaatatt tccggtccaa cagatacttc
     9181 cctgtcaact ggctgcgggt acgaaactcg cttcacggca tcgaaaacgc cgaacaacgt
     9241 ttcagcccct cccgtatccg ccagatcaaa aaaggcctga aaaatggagc aaaagtagac
     9301 gaggcacgta cggtagaaga gatacgcgaa ttttcgaata tgctgaggca tctctattcg
     9361 tcccgcatcc gtaaacattt tcccaacatc atctttttcc agcacatgga cacccggctg
     9421 attcacagcc ggcaggcaaa gattttcatc gtccgctaca aagacaaaat tatcggagga
     9481 tctgcctgta tctattcggg aaacgatgcc tatctctggt tttcgggagg tatgcgaaag
     9541 acctatgcct tgcaataccc gggtatactg gctgtatgga aagccctcca ggatgcccat
     9601 caaaacggat tccgccacat ggagttcatg gacgccggac tcccatttaa gaagcacggc
     9661 tatcgtgact tcgtgctccg cttcggtggc aagcaaagca gcacccggcg atggttccgt
     9721 ttccgctggc aatggctgaa cgacctgctg atcaaaatat acgtctgaac atccgcctgt
     9781 ctcagggatc agcgccaacc ctctccgcct tttaaaccac ctcccttagg ttttaaacca
     9841 acgatacctg ccttttaaac ccatgcacct taggttttaa acctattttc accataatta
     9901 attgcagaaa aatttcttta ttaaacaaga attgattttc tttgtgctgt tttataccat
     9961 tccgaaaaga cgattaatac caaaatttaa aaatatagtt atgaagattt cacacattga
    10021 acatttgggc attgccgtaa aaagtatcga agaagccctt ccgtattatg aaaacgtttt
    10081 aggtttgaaa tgctacaaca tcgaaactgt agaagatcaa aaagtaagaa cagccttcct
    10141 gaaagtaggt gataccaaaa tcgaattact ggaacccaca tgtccggaaa gtaccatcgc
    10201 gaaattcatc gaaaacaaag gtgcaggtgt tcatcacgtg gcattcgcca ttgaagacgg
    10261 cgtagccaat gccctagccg aagccgaaag caaagagatc cgcctgatcg acaaagctcc
    10321 gcgcaaaggt gccgaaggcc tgaacattgc tttccttcac ccgaaatcaa ctctgggcgt
    10381 actgacagaa ctctgcgaac actaaaaaga tgtacgattc ggacgatccg cgccacggac
    10441 aaacggaatt tttctttgca ttaaattccc catccgggtt gtcaatcgtc cggttgtaaa
    10501 tattataacc ctttaaatta agaaaaactc atgagtaacc agcttgaaaa agtaaaagag
    10561 cttattgaac ttcgtgctca ggctcgttta ggtggtggcg aaaaggctat tgaaaaacaa
    10621 cacgccaaag gcaaatatac agcccgcgag cgtattgcac agttgcttga cgaaggtagt
    10681 ttcgaagaac tggatatgtt tgttcaacac agatgtacca atttcggaca agagaaaaaa
    10741 catttcctcg gcgacggtgt ggtaaccggt tatggaacga tagaaggtag attagtatat
    10801 gttttcgcac aagatttcac agtattcggt ggttcactgt cggaaaccat ggcacaaaag
    10861 atctgtaaag taatggatat ggccatgaag atgggtgccc ctgtcatcgg tatcaacgac
    10921 tcgggtggcg cacgtattca ggaaggcatc aacgccctgt ccggttatgc tgaaatcttc
    10981 cagcgcaaca tcatggcttc gggtgtcatc ccacagattt caggtatttt cggtccgtgt
    11041 gccggcggtg cggtttactc tcccgccctg acagacttca cgctgatgac ggaaggtaca
    11101 tcttacatgt tcctcaccgg accggctgtt gtgaaaacag taacgggtga agacgtgtct
    11161 caggaagatc tgggtggtgc aagcgtacat gccagcaagt ccggtgtaac tcacttcact
    11221 gccgaaaccg gtgaagaagg tctggcgatt attcgcaagc ttctcagctt tattccgcaa
    11281 aacaacctgg aagaagctcc attggtgaac tgtaccgacc ccatcgaccg tatggacgac
    11341 ctgctgaacg agatcatccc cgacagcccg aacaaaccgt acgatatgta cgaagtgatc
    11401 ggcgccatca tcgataacgg agaattcctg gaagtacaga aagactatgc gaaaaatctt
    11461 attatcggtt ttgcccgtat gaacggacaa tcggtaggtg tggttgccaa tcagcctaaa
    11521 tacctcgccg gagtactcga cagcaatgct tcacgcaaag gtgcacgctt cgttcgcttc
    11581 tgcgacgcat tcaacattcc gctggtgaca ttggtagacg ttccgggatt ccttccaggt
    11641 acgggtcagg aatataatgg tgtaatcctg cacggagcca agttgctgta cgcttatggt
    11701 gaagccactg tgcccaaagt aactgttacc ctgcgtaaat cttacggtgg ttcgcacatc
    11761 gtaatgagtt gcaagcaact ccacggcgac atgaactatg catggccgac agccgaaatc
    11821 gccgtaatgg gcggtgccgg tgcagtagcg gtattgtatg ccaaagaagc caaagatcag
    11881 gaaaaccctg ctcaattcct ggcagacaag gaagccgagt acactaaact gttcgccaac
    11941 ccatacaatg cagccaaata cggttacatt gacgatgtta tcgaaccgag aaacactcgt
    12001 ttccgcgtga tccgcgccct gcaacagctg cagaccaaaa aattaaccaa ccctgctaaa
    12061 aagcacggta atattccatt gtaacaaatt aaacatcgat tgttatgaat aagaaaagaa
    12121 tcgggatatt tatcgctctg ctggcaatgg tttgcatggg gctcagggcg caaagtgcca
    12181 ccagtctgag aatcaatgag gttttggtcg tcaacgacca gaactatcag gatgactacg
    12241 gactgcacaa tgcgtggata gagatattca acacctcttt cgcttctgta aatctggaag
    12301 gttgctttct gacgaacgat aaaaacaatc cgaccaaata tcctattccc aaaggcgacg
    12361 tgctgactct gatcaagccg cgccaacatg ctttgttctg ggcagacgga atgcctaacc
    12421 ggggtacgtt ccacgtgaac tttacgctcg acccgaacaa agagaattac attgctttgt
    12481 atgactctaa cggtaaaact ctgattgacg aagtaaccat acccgccggt cagcttgccg
    12541 accgttcata cgctcgcgaa aaagacggaa gtgccaactg ggtagtaaaa ggtgaaggag
    12601 aacacagcta tgtcactccg agcaccaaca atatgactat cgacaaaaac ccgaagatcg
    12661 agaacttcaa gaaacacgac tctatcggta tcggtatggc catcatcgcc atgtcggtcg
    12721 tattcatagg tttggtactc ttgtatcttt cattcaaggc ggtaggtaac gtagcggtca
    12781 gactgggtaa gaaaaacgcg atgaaagcca ccggtatcac cgacaagacg gaagcgaagg
    12841 aaaagaacct gggtagccac acaggtgaag aaaccgccgc gatcgccatg gctttgcatg
    12901 aatacctgaa tgacgctcac gacgttgaag acatgatttt gactatcaac aaagtgaaac
    12961 gcacctactc accctggagt tcgaagatct acacactgcg tcagactccg aaaagataat
    13021 tactaaccct aataaaatga agcaatgaaa caatataaat ataaaatcaa cggcaacctt
    13081 tacaacgtta cagtgaacga tgtagaagat aacatagcca acgttgaagt gaacggaacc
    13141 tcttataaag tagagttgga caagcccgtc aaagccgctc cgaaaccggt gacccgcccg
    13201 gcagccgctc cgaaaacgga aacaggtgct ccggtagtaa ccaaacaacc gacagcttcc
    13261 aaaaaagacg gtgtgaaatc tccgcttccg ggcgttatcc tcgacataaa agtgaaagaa
    13321 ggggataccg tgaagagagg ccagacgatc atcatccttg aggctatgaa gatggaaaac
    13381 aacatcaatg ccaataaaga cggaaaagta gcagaaatta aagttaataa aggagattct
    13441 gtacttgaag gtacagacct cgtaatcatt gaataattat gggagatttc gtatcattct
    13501 tagggaataa ccttgttgac ttctggggat acaccggttt tgcgaacgcg acacccggac
    13561 atcttttcat gttgctaatc ggtctcttct ttatctacct tgccgtagcc aaagaatttg
    13621 aaccgatgct gctgatcccc attggcttcg gtattctgat cggtaatatt ccattcaata
    13681 tggaagccgg attaaaagtg ggtatttacg aagaaggttc ggtactgaac atcctttatc
    13741 aaggagtaac ctccggctgg tatccgccgc tcattttcct gggtatcgga gccatgacgg
    13801 acttctcggc gctgatctcc aaccccaaat tgatgctgat cggagctgct gcgcaattcg
    13861 gtatcttcgg cgcgtatatc attgccctgc tcattgggtt cgaacccaac caggcgggtg
    13921 ctatcggtat cattggcggt gccgacggac cgacggccat cttcctttcg tccaaactgg
    13981 ctcccaacct gatgggtgcc atcgctgtgt cagcctattc ttacatggcg ctggtgccgg
    14041 tgatacagcc acctatcatg cgtgcgctaa ccaccaaaca cgagcgtctg atccgcatga
    14101 aaccaccgag aatagtatcg catacggaaa aagtaatctt ccccatcgtg ggtctgttgc
    14161 ttacatgctt cctggttcct tcgggtctgc ctttgctggg tatgctgttc ttcggtaatc
    14221 ttctgaaaga aagtggagta acccgtcgtt tggcaaatac ggccagtggt ccgttgatcg
    14281 atgtgatcac tatcctgttg ggactgactg tgggagcttc tacccaagct tcacaattcc
    14341 tcacctggga ttctatcttg atctttatcc tcggtgcatt ctctttcatc atcgcaacag
    14401 cgtcaggtgt catgtttgtc aaattcttca atctattctt gaagaaaggc aataagatca
    14461 atccgctgat cggtaatgca ggtgtatctg ccgtacccga ctcggcacgt atttcacagg
    14521 taatcggttt ggaatatgat ccgaccaact atctgctgat gcacgccatg ggtcctaacg
    14581 tagcgggggt tatcggttcg gctgtagctg ccggtatcct gctcggattc ctcatgtaaa
    14641 cgatattttt ttcattagta aggtagacgt tcttcttttc gcaaagaagg gcgtcttttt
    14701 tttgcgttaa tctatctaaa agatattacg aatctttcgt agaatggata tttttactaa
    14761 cttgcggaca ataaaacaat acgtcctatg agaacaagaa caatgaaacc actcttcctt
    14821 attttctgtc tttgcctcag tcccctactg atgggccaga atcaaaacaa aattcaggaa
    14881 gcaatggcaa actatgacta cgagactgcc gttgaactga taaacaagga acctcccacc
    14941 atcccactgt taatgcagaa agcaaaagcc ctgaaaggaa tcggcagcaa tgcggaagct
    15001 ctacgttcca tccgccaagt gatagcggaa gactccacca accaacaggc acacatcgaa
    15061 gcagcggaat gctgtaaagc aatggccaag tacaacgatg cgctggacta ctaccggaaa
    15121 gccatcagcc tgaatcccaa aaacaagtat gcccgtttgc aattcatcaa cctgctttgc
    15181 aacaccaaaa actatgctga ggcttttgga gaaagttcaa tgatgtccga aacggacagt
    15241 tcggccgtag tgctccacct acaggctcaa agccttgaag ggatgcaaca gatactaccg
    15301 gctatcggtt gctatgaagt cattcaggat aaatatccgg acgattatct ggctgcggcc
    15361 aaactcggaa acctgaacat tgtggctgga tatcccgaat atgccatcca agctaccgaa
    15421 cgctataggg aacgggactc caccaacctg attgtcaacc agcaaaacgc tctcgcctac
    15481 tgccacgccg aacaatatcc gacagccatc aagcgctatg aaaagctgtg ccaacagggg
    15541 gacagcagta cacagacctt atactacctg ggagtcagct attacgcgga tgaatattat
    15601 tacgaagcgc acgcgtgttt cagcaaactg caaaaagaga tggaagaaaa tcccaatctg
    15661 ctctattatc tgggacgttg ctgcgccaag acttcctgga aaaaagaagg catcgaacac
    15721 ctggagaaag ctatcgaact gaccattccc aaagacagca ccatgatccg actttacaaa
    15781 ggcttggtgg attgttgtaa actggctcag gatactccaa agcaaatcca ggctctcaga
    15841 gaactgtaca aatatgacaa gacgaaccat aaacttcttt atgacatcgc ctggaactat
    15901 tcatatcaac tcaaagacaa caaatcggcc gaacgttatc tgcaggcttt cttaaaaacc
    15961 cgaaaggcga atgccaggaa agaagaaccg gtgagtgaga aaggggaact tgtactcgga
    16021 cttgaaaatt attacaacgc tgccgaaaat tggctgaaag acttacagaa agaaaagttc
    16081 ttcaaagaag gaataccgtt agaaagtcag aaacaataga atctgtcccc cccccatgaa
    16141 acattggata ctcctcctct atctggggtt cagcgtagtg ctgcaagccc agaacaccgc
    16201 ctccgttcaa gaagcaatgg caaactatga ctataaaacg gtgatcagac tgattgatga
    16261 agaaagtgca tcaccacagt tactcataca gaaagccaaa gctttaaaaa gtttagggcg
    16321 taccgccgaa gccctgtcca ctttgcaaca tatcattatc gagctgcccg aaaatcagca
    16381 ggcattggta gaggcagcag aatgttgcag gcaattgagc aaatttaacg aggccttggg
    16441 gtattatcgg aaggtgatgg aactcaatcc cgaacatatt tacgcacact tgcaatacac
    16501 ccgcttgtta tacaactatc agcgatacgg cgatgcattg cgtgagagta tcgcattggc
    16561 caggaaagac agttccgcca ccgtattgcg actgatggcg gaaagcatgg aaggagccgg
    16621 catgccggta gaaagtatgt tttgctatct ttccatcatc aggaaatatc cctccgacta
    16681 tctctcggta gctaagctgg gcagtatctt caatacaatg aaagattacg aaggggcaat
    16741 tgccctgaca gaagcatacc gccggacgga cagcaccaat gtagaagtga accgtcaaaa
    16801 cgcactggcg tattgtctgc gcaaagaata tcccaccgcc atcaaacgtt atcaggatct
    16861 gaccgcccgg ggagacagca cactgctgac atgttattac ctgggagtca gctactacgc
    16921 tacgaaagaa tactataaag cgcgcgattg gctactcaaa gcaaaatcat gccagtcacc
    16981 cggcgccaac ctactctact atttgggacg ttcgtgctcc aagacattat ggaaacaaga
    17041 gggaatagga tatctgaacc aggctatcgc cctgactatc cccgccgaca gtatcatgga
    17101 gcgcttatac tcaggcttgg cagactgcta caggcaaacc aagcaaaccc gggaccaaat
    17161 caaggctacc aaagaacaat acaaatatgc ccctgacaag catattttac tttataactt
    17221 ggcgttctta tcggacaaaa taggagatac taaagccaca gagcattact tgcaggcttt
    17281 tctgcgaaca aaatccaaac aaaatgcagt actacagcag ccggatgatg acgaagaaga
    17341 acccgcaccc tacatagatt actacaaaag tgccaccaat aaattggaaa gcatccgaaa
    17401 agagaaattc ttaaagggag aaaagtgaat tgatcggata gatgcatcgt ttcggacaat
    17461 tcaccactga gtgcagacag agtttcacag agggagaata atggaaaata aatttgaaga
    17521 tgtgcggtag aaggcacagt ggcacgtaac cgaagtcaca tcggcacgca gccgaaatta
    17581 cggtgctgtg tagctaaagt tacggtgctg cgtagccaaa gttacggnnn nnnnnnnnnn
    17641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17701 nnnnnnnnnn nnnnnnnnnn nnnnnnntgc tgcgtagccg aagttacggt gctgcgtagc
    17761 cgaagctatg acggcatctc cttttccgga cgtcacgttc acctgattgc atcgaaaagt
    17821 gttccttatc ggttgagctc catcccggag aattctccaa tgaaaacgtt tgcataaata
    17881 gatggcacac agtaagaaag aaaacggaaa acaatccgat gatttaccct atattagcaa
    17941 cattaaataa taacgagcta atatcatgaa aaaattattg ttactcttag gttcattcct
    18001 actgtcatta accacttatg cagccatgaa catatccaaa atcgatccgc ccttctggtt
    18061 caccggtatg aacaatccgg aactccagtt aatggtatac ggtgaaggca tcggccaggc
    18121 atccgtatca gtaaattatc ccggtgtatc gctcagcagc gtcgtgaaac tggaaagcaa
    18181 caattacctg cttgtctacc tgcatctcga taaagaagta aagccgggca agatgcccat
    18241 cacatttacg gtcggaaaga agaaattggt gaaagagtac gaattgaaag cacgcagcaa
    18301 agccggagtc gatcacaaag gttttgacgc atcggatgca ttatacctgc tgatgccgga
    18361 ccgttttgcc aatggcaatc cggataacga ccggatagaa ggcatggccg aatataaagt
    18421 ggaccgcaac gacccgaacg cacgtcacgg aggcgacctg gccggtatcg aacaaaatct
    18481 ggactatttt accgacttgg gagtgaccgc actctggttc accccggtac tcgaaaataa
    18541 tatgaaaggc ggctcatatc acggatatgc aacaaccgat tattacaagg tagacccacg
    18601 tttcggcact aacgaggaat atcgctcact gatagcgaaa gcccacaacc ggggcattaa
    18661 ggtcgtgatg gacatgatct tcaatcattg cggagtagaa catccctgga tcaaggacat
    18721 gccttcaaag gactggttca accatgcgga cttcaagaac aactttgtgc aaacttccta
    18781 caagctgact ccacatgtag atccgtatgc ctcggagtac gatttcgacc agatgaacaa
    18841 cggctggttc gtggaagcca tgcctgacct caaccaaaag aaccctcacg tatacaaata
    18901 cctcttgcag aacagcctgt ggtggattga gtacgccgat atcgacggca tccggatgga
    18961 cacctacccg tatgccgatt acgatgccat gagcaactgg atgaaagaac tgaacgaaga
    19021 ataccccaac tacaacacgg tgggcgaaac ctgggttacc gaaccggcct atacagcctg
    19081 gtggcagaaa gactccaaac tctccgcccc gcgcaacagt cacttgaaaa cagtcatgga
    19141 tttcagcttc ttcgacaaag tcaacacggc caagaatgaa caaacggaca cttggttcaa
    19201 aggattggac cgtgtctaca acaattttgt atacgattat ctgtatccca atccggcttc
    19261 cgtactggct ttcatcgaga atcatgacac cgaccgtttc ttgggtgaag gcgaaaacct
    19321 cgatatgctg aaacaggcct ccaccctttt attgaccacc cgacgcatcc cgcaactcta
    19381 ttatggaacg gaggtgatga tgaacggagt aaagagtaaa agcgacggct atgtacgaaa
    19441 ggacttcccg ggcggatgga cggacgataa agagaatgcc ctgactcccg agggacgtac
    19501 ccgattgcag aatgaaagct ataacttcta ccgcaacctg ctgaactggc gtaagggcaa
    19561 cgatgtgatc gccaaaggca gcatgaaaca gttcatggtg cagcacggcg tatatgctta
    19621 tgcacgccaa tataaaggga aaacggtatt cgtcctgttg aacggtacgg ataaagaggt
    19681 gaaacttccc ctgaaatact atgccgaagt gctgaaagac aagactcaag gaaaagacgt
    19741 cattagcgga aaagtaacgg cactcaatga agaactgaca atggcacccc gccaatcgat
    19801 ggttatagag ctttaatctc acaccggtta taaccgcata agcaaagggc acaaaggatt
    19861 tcacccgaca tcctctgtgc cctttgtgta gcctaatgcg aataataata gtcaaacgtt
    19921 tgactattat cggagaatat tcctaccttt gcagcgacta aaagaatacg acgatgacaa
    19981 acaacgaatc ggagcgcgag ctcgtcctac aaaccttacg aacctggatg gcattccgcc
    20041 aggccgttca gcgggtactc aaacgccaca acgtggatat gaccttcgag atgctgcaag
    20101 taatgaactg cctgtggaac aaacaaggca tcagccagca atccctggct gagaaaacag
    20161 caaaggacaa ggcttgcctg accaatctga ttaataatct ggaaaagaaa aactgggtga
    20221 tacggaaaga aggcccctcc gaccgccgaa accgcctgat tttcctgacg ccccaaggcg
    20281 aagaacttgc cctcaccgtg aaacccctga tcaacgatat ctatgcccaa accggagcag
    20341 agatggaggc aagccggata acggaatgca tcgaagacct gaagagactg catgaagtgc
    20401 tcaatgagat ctaaaagaaa tccgccatgt ccacccgtca gataaagcta aaacaattga
    20461 gaagactgaa gttcaggaac atctttctca acacagtatg catcctgctg gcattggcag
    20521 gtatttcatg gacagtaaac tacttctgga aatacgcccg ctatgagata accaatgatg
    20581 ccgtagtgga tcaatacatc gctccgctaa acatccggat accgggctat atcaaagaag
    20641 tacgttttac cgaacatcag tatgttcatg ccggcgacac gttactgata ctggacgacc
    20701 gggaataccg gatccggctg aaagacgcgg aagcggcctt gatggatgcc ttgggatcaa
    20761 aggaagtgtt aaactccggc atccggactt caggagtaaa tgtagccgtg caggaagcca
    20821 acatagccga aacactggca cacctttcac agcaagaagc ggaactgaac cgatataccc
    20881 ggctcctgaa aaagcaggcc gtcagccaac aggattatga actggccaaa gcgaacttcg
    20941 aagcgacccg ggcaagatac aacgccctgt tgcgacaaaa agaagcggcc caatcgcagt
    21001 attccgaaac cagcaaacgc agtacaggcg ccgaagccaa tatcctccgg aaggaggccg
    21061 acctggagat ggcccgacta aacctgtcgt ataccgttgt caccgcaccc tatgacggat
    21121 acacgggacg acgtacactt gaaccgggac agttcgtaca aggcggacaa actctttcct
    21181 acctggtacg gggcaatgac aagtgggtga cagccaatta taaagagact caaattgccc
    21241 atatctatat cgggcaaaaa gtccgcatca aagtagatgc tttcagcgga cgcacttttc
    21301 acgggaccgt aaccgccatt tccgaagcca ccggatcgaa atactccctg gtaccgaccg
    21361 acaattcggc agggaacttc gtcaaagtgc agcaacgcat tccggtccgc atcgatctca
    21421 atgacgcctc acccgaagag atggaatgtc tccgtgcagg gatgatggta gaaacggaag
    21481 cggtccgccc ttaggcttat ggtgaagctc aatctgccta cccgtccctg ggtgcctcaa
    21541 tggttgggca tcgtgaccat gtttattgtc atctttccca tcaccctgct caacggtgcc
    21601 tacacaggaa gtatggtcga agtatcgaac acgctgggag tattgagcga agatattacc
    21661 atggcttact attcagcttc ggtagggata gctgttgcct atcccatcgt accgaaaata
    21721 cgcaccatag ccactccgaa aaccttactg cttaccgacc tgctgctaca gatattcttc
    21781 agcctggtat gcgccaaaac cggtagtatg gatgtcatca tggtatgcag tttctgtatg
    21841 ggatttctca aagccttcgt catgttggag ttcatcatcc tgatccgccc gctcttcagt
    21901 ccgaaaaacg tacgaagtga attctatgcc tacttctacc ccatcgtttt ctccggaggt
    21961 cagctatcga tggctatcac cgctcaactg gcctatcact accaatggca gcacatgtac
    22021 tattttgtca ccatcctctt gctgatcgcc attctgttcg tcatctgttt cttccgctat
    22081 gcaaggcgtc ccatgcacat tccgttcaaa gaaatggacg gaagaagcat gttcatcatc
    22141 gccaccgctt tcctgctaac gctctataca tttacctacg ggaaaacact cgattggttc
    22201 gcatccccga agatcagagt atatgtattc gtcatcccgc tcctgatagc tcttttcatc
    22261 catcggcagc gtacacaagg caaacccttt gtcagcctga aaccactctt tctgcataaa
    22321 tccatcatcg gatatggctt catggtactc gccatgttcc tgacagccac cagttcactg
    22381 gtaaccaact atatgaacag catcatccgg gtagacagca tacacgccaa ttcgctgagc
    22441 ctgtggctat tgcccggata tgtggtaggg gccgtcattt gcttctggtg gttccgatgg
    22501 caacgatggc ggtttcgctt cctcatttca ggaggtatgt tctgctacgt catctatctg
    22561 gctatcctct actttggtat caccccttat ggaacttatg aaatgctcta cctccccatc
    22621 ctgttccggg gagtggggat gatggtcata ttcattgcgt tcggtgtgtt tgttgtcgaa
    22681 gatttagacc cgcgcctgac gttgtccaat gccttcttcc tgatttcatt ccgctcagta
    22741 ttagctccgg tcctgtccgc ttcgttcttt aacaacatgc tttactatct gcaggcaaag
    22801 gggatgaaca ttctttcgga aaacatgacg ctgaccaatc cgctggccga acaaaaatac
    22861 aatcaggcat tgagcaatgc cctggcgcaa gggcacgaat tcggcgaggc cggacaattg
    22921 gcagccaaca gtctgtactc cactttgcag cagcaatccc tgttgcttgc cctgaaaacc
    22981 ctaatcggct atgtactgat actggcactg gtgattgctg tcatcgcagc gttcattcct
    23041 ttccataaaa cgctgaaggt ggctgtagtg aagacgggtg acgatatggt ataatgagaa
    23101 gagatacaaa aaagccaccc aattgcttga gtggcttctt aaaatataaa ttaaatcaag
    23161 taaaactttt aaatactaga tttggaattt attcagctaa cttgttgtca gaacccagca
    23221 cgttgataat tttgtgcttg tagagttttt ccatattgtc gcgagccggt cccagatatt
    23281 tacgcgggtc gaactcagcc ggtttttctg cgaatacctt acggatagca gcagtcatag
    23341 ccaggcgaga gtctgagtcg atgttgattt tgcaaacagc agacttagcg gctttacgca
    23401 gttcctcttc aggaataccg atagcagctt tcagtgcacc accaaactgg ttgatagttg
    23461 caacctcttc ttcaggaact gaagatgatc cgtgaagaac gatagggaat cccggaagtt
    23521 ctttcattac accgtccaat acgtcgaatg ccaacggagg aggaaccata cggcctgtct
    23581 tcggatcgat gtggcactgt tccggagtaa atttgtaagc accgtgagaa gtaccgatag
    23641 agatagccaa tgaatcgcaa cctgtcttgg taacgaaatc aactacttcg tccggttcag
    23701 tatatgtgtg gtggtcagaa gaaacttcgt cttctacacc tgccaatacg ccaagttcac
    23761 cttctacagt tacatcgaac tggtgagcgt attcaacaac tttcttagtc agagcaacgt
    23821 tttcgtcgta aggaaggtga gaaccgtcga tcattacaga agagaagcct gagtcgatac
    23881 agcttttgca agtttcgaaa gtatctccgt ggtcgaggtg caaaacgatt tcaggatttt
    23941 tgcagccgag ttcttttgca tattctacag caccctgagc catgtaacgc aacaatgtag
    24001 cgttagcata ctgacgagca ccttttgata cctgcaaaat aaccggagac ttagtttcta
    24061 cagcagcctt gatgatagcc tgcatctgtt ccatattgtt gaagttgaat gcagggattg
    24121 catatccacc cttgatagcc ttagcaaaca tatctctagt gtttaccaga cctaaatctt
    24181 tgtaattaac cattttgttt aaaagtttat tgttagtgaa ttaaaaattc tatgcaaaag
    24241 taagaataat cctttgaata gagaaaccct cgggcggaaa tatccgtttg aggagcgtaa
    24301 ttcaattcta tttcaaatta tttcccatcc tttaagagct gtttgtaatg tctacgtagc
    24361 aaataaaggt tttttattgt ttcctcatat atataatggt aggcaaatga tcgctgtaac
    24421 catccaacca cactctgcca ccatatgtac gcaggggtgc acccttatat ttaccatcct
    24481 gctgaaacag gtaatcgcgc atgaaaactt cattgtgatc atatttcaat ccttttgtgg
    24541 cttgaagcag cgtgggcgaa aggatgatct gatcgaacag attccatttg ccgcgataga
    24601 gcaaagtgcc cactccctta tcttccagcg tcacccacc
//
