LOCUS       c00180_gnlPro..        14598 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KPIFLIGA_202.
ACCESSION   c00180_gnlPro..
VERSION     c00180_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 04:29:01
            Original ID  :: gnl|Prokka|KPIFLIGA_202
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14598
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14598
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[65:4598]"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      66..4598
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
     cand_cluster    1..14598
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /kind="single"
                     /product="fatty_acids-unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14598
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="fatty_acids-unassigned"
                     /region_number="1"
                     /rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /tool="gutsmash"
     CDS             66..836
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg180_1"
                     /sec_met_domain="ECH_1 (E-value: 4.3e-67, bitscore: 216.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTVDFTVKNHVGWLTLNRPDKLNALNETMNREIMDVLTAAEQDP
                     QIRALVLTGAGRAFCSGEDLGSLNEQADHGEIIRKRYIPMVKKIAAFEKPLIAAVNGPA
                     AGAGFSLCLACDFRIASEQATFLNAFIHIGLVPDTGNPYFLPRIAGYAKALELSCLGEK
                     ISAPEAMEYGLLTKVVPACHLEKETQHFAERLAAMPTKAIGLIKRYMQKSFESTLDEML
                     EKEAYAQRIAGQTADHQEGVRAFFEKRKPEYKGN"
     CDS             916..2373
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg180_2"
                     /sec_met_domain="Aldedh (E-value: 4.5e-181, bitscore:
                     592.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVINGEPVDAAGRETFHVYNPATGEPIATVPKADYADADRAVEAA
                     RHAFEHGKWRRYPVGKRARVLNKIASIMRSRFDALVEMEILNTGKTTETAKGQVMQAIE
                     DFEFFAGAIVGHRGAVNHVPGQFFNYTQKEPVGVAAQIIPWNYPLMMAAWKIAPAIAAG
                     CSVVVKPASLTPITAILLAEICHEAGVPAGVVNVITGPGAKIGSYLAKHEGVDKIAFTG
                     ETSTGKEIMANASETLKRVTLELGGKSPNLVFRDADIDAAVNGALYGIFYNTGQSCEAR
                     SRLFLQEEIYDAFMEKFVAKTKKLVLGDPFSPASHIGAIISKGQLETIHRYVEEAKQAG
                     ATIVTGGKPAKVEGFENGYWYEPTIITNVTNDSKIAQEEIFGPVVVVMPFKEEKEAVKL
                     ANATKYGLASSIWAKDQGLIKRVADSIQAGIVMVNSPFSAFPGTPFGGYKQSGFGRELS
                     FECLDLYSETKSVLTYAGAKPLNPFQL"
     CDS             2530..3396
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg180_3"
                     /sec_met_domain="HCDH (E-value: 2.3e-34, bitscore: 108.4,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 1.1e-61, bitscore: 198.2,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMAETLVVIGSGVMGRGIAYAGALGGFKVRLVDVRPDILHQAENI
                     IGSVMEKGLARGKINGADAERIKANIEYTVDLPAVAGSADVIIEAVPEKMEIKKEVFEK
                     MDRFAPAGCILATNTSTMSPTEIGSFTTRPASVIAMHFFNPVHKMPLVEIIRGLETSDE
                     TVQRAEKAAEKMGKETVIVNEFPGFVTSRISCLVGNEAFCMLQEGVGTAEEIDKAIKLG
                     LNFPMGPFELADLVGLDARLNNLRHLHEKLGEKYRPAPLLEKYVKAGRLGRKTGKGVYD
                     YTTVEGE"
     CDS             3399..4598
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg180_4"
                     /sec_met_domain="Thiolase_N (E-value: 4.1e-85, bitscore:
                     275.6, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 3.1e-52, bitscore:
                     165.9, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDVVIVDAVRTPIGRYKGALKSVRPDDLAASAIKALLARHPEVP
                     WNEIEEVILGNANGAGEENRNVARMAALLAGLPVETAGTTVNRLCGSGLDAVNIAAKAI
                     MAGDGDIYIAGGTESMTRAPFVMAKPENGYPRGNLEMFDTTIGWRFVNEKLKKMYGTDS
                     MPETAENVAKQFHISREAQDAFAFTSQMRAKAAMEANRFQDEIVPVVYTDQKGESVSVI
                     RDEHPRPDTTPEKLARLKPLFAGGTVTAGNSSGINDGASAVLLMSAEKAVQLGIKPMAR
                     FAASATAGLEPRLMGLGPVYATRKALKRSGFNISDIDLVELNEAFASQSIACIRQLELD
                     SDIVNVNGGAIAFGHPLGASGARILTTLVHEMQKRKAKRGLATMCIGVGQGIATVIEKI
                     "
     CDS             4641..5534
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PaaX"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg180_5"
                     /sec_met_domain="PaaX (E-value: 5.4e-34, bitscore: 106.8,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKTLNTRSMIFTLYGDYIRHYGSEIWIGSLIKLLEAFGHHEQSV
                     RAAISRMSKQGWVESRKEGNNSYYSLTERGVKRMNEAAGRIFKLNPGKWDGKWRFFLYT
                     IPEKKRNIRDELRKELVWSGFGLLLNSVWLTPNDLLDEMKGIIDKYGINEYVKIFTAEN
                     VWGKSDKELVHELWDIDYMNDRYEDFMAHYREKYESVKEKMKRGEMTNQDCFVERTLLV
                     HNYRKLLFVDPGLPEELLPEKWKGEEAAALFRDYYRILAKPANDFFEDIFSEGYGTFQK
                     SKHYDVFDHPLITEKA"
     CDS             5565..6515
                     /locus_tag="ctg180_6"
                     /transl_table=11
                     /translation="VANPVTEMLGIKFPVFQGGMGNISDPALAASVSNAGGLGTIGAGT
                     LPVAEIEKRMDKMRSLAASPCCVNIAISVHPNASEVIRLAIEKKIPVVSLSAGNPSKYI
                     PVLHQNGIKVICVSSTVRQAKKAEAAGADIIVCEGYEAAGINAANESTTMVLVPQIVKA
                     VSIPVVAAGGIADGKGLAAALSLGAYGVQMGTRFIATKEAQFHPVYKNAVIEATDEATM
                     IIGRPYQMLRRVFKNVYAGYLRELEESGADPGRFKKLTSEAHHERGALQGDMEHGFING
                     GQIAGLIEDCPSVAQLLEEMVKEARAVLTRSMARL"
     CDS             6676..7560
                     /locus_tag="ctg180_7"
                     /transl_table=11
                     /translation="MEIDAVFSGGGIKGLALIGALEVLEKKGFTFKRLAGTSVGSVFAG
                     LRAAGYTSGEMKQMLAETDTAAFLDQRKPLLPVPFAKWLLLYWRLGLYRGTAFEEWIGE
                     KLASKGVYTFKDVPKGSLYFTASDLTHNRLVVLPDDLERYGVPWQTFPVAKAIRMSCSI
                     PYFFEPVRLRSLEGTSLIVDGGVLSNFPMWLFVKPEEKKARPVLGITLSPKQPEEPDVE
                     IKNAIQLFDALFKTMKDAHDARYISRKLEKDIIFIAVDGVTATDFQLSAAQKAALIEAG
                     RKKTETFLKTWSY"
     CDS             complement(7577..7945)
                     /locus_tag="ctg180_8"
                     /transl_table=11
                     /translation="LLKTRQWIIAGIFLLALVGLGSSLFHEPVVFLKRVLIAFIFAAVL
                     LAGIRFLLKRSTNVSNQEQKAFLKAARKSRKRMKKRNMKVHTVHTVKFSKRPLRKKSNV
                     QLTVIEGKKGKKKNRAVY"
     CDS             complement(8101..8979)
                     /locus_tag="ctg180_9"
                     /transl_table=11
                     /translation="MFGGKRHSVTAIRRKNNRIDFFYLPKETRPSVQKLKKIPFLRGII
                     AIIESSANGAKHLNFASERYDVDPEEDEKRKEAAPAKTTVVLGVAAAGVLSFLFAKFFM
                     TLIPVFLAELARPFFPGDAAQILIEGAFKLLLVLSYIYLISLTPFIKRVFQYHGAEHKV
                     INTFENGLALTVENVRSQSRLHYRCGSSFILFTVIVSVLIYTLVPTDPLWLRITDRILL
                     IPVVLGTAFEVLQLTNKVRHIPVLKYLGYPGLWLQLLTTKEPDDKQIEVAISSFQALLE
                     LESGDTDSAAR"
     CDS             9209..9727
                     /locus_tag="ctg180_10"
                     /transl_table=11
                     /translation="MENGSKVLKNQEHSMTFFQMVLVTGFAGGIIWSLVAYLYFSFHFT
                     AIEPNVLLEPFTVGSWRNMWIGKIISILVYGLLSTGCALVYYLFFKKLKSMWVGAIYGL
                     CLCAVVLIVLNPIFPGMKPFLKLDANTIITCCCIYILYGVFIGYSISFEYERSRVFKRK
                     LERQTNPLP"
     CDS             9854..10309
                     /locus_tag="ctg180_11"
                     /transl_table=11
                     /translation="MKKYLVLNGPNLNLLGQREPGTYGKDSLKTLMARMEAAARKHGVA
                     IGFFQSNHEGALIDKLHAAGDEGFAGIIFNPGAFTHYSYALRDAISAIRLPVIEVHISN
                     IHAREEFRHHSVTAAVAQGQIAGFGLYGYELALMALLEAEKGEEERC"
     CDS             10303..11364
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M24"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg180_12"
                     /sec_met_domain="Peptidase_M24 (E-value: 2e-70, bitscore:
                     227.1, seeds: 437, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKLEKLRETFPQAGIDGLLITSPYNRRYMSNFTGTTGIVLISGE
                     AAKFITDFRYVEQASKECEGYEIVQHQGPVEQEVAKQVEAMGIKRLGFEQDHMSYALFK
                     TYEGLLDAELVPVSGLVENLRLIKTDAEIKILKEAADIADVAFKHILDFLKPGVTELEV
                     SNELEFFMRKCGATASSFDTIVASGLRSAMPHGVATDKVIEKGDLVTMDYGALYKGYCS
                     DITRTVAVGEPSGQLKKIYNIVLESQLLAVQNIKPGMSGIEADAISRDYIARKGYGDAF
                     GHSLGHGIGLEIHEGPNLSMRSGYTLEPGMVVTIEPGIYVPGVGGVRIEDDTVITENSN
                     ELLTHSAKELIIL"
     CDS             11414..11971
                     /locus_tag="ctg180_13"
                     /transl_table=11
                     /translation="MISVNDFRTGLTIEVDGGIWRVLDFQHVKPGKGAAFVRSKLRNLR
                     TGAIQEKTFRAGEKVERAQIDNRRMQYLYANGDQHVFMDTETYEQIELSSAQIKDELQY
                     LLENMEVQMIMYQGETLGIELPNTVTLTVTHTEPGVKGDTATGGSKPATLETGLTVQVP
                     FFVNEGDKLIINTTDGSYVSRA"
     CDS             12180..13106
                     /locus_tag="ctg180_14"
                     /transl_table=11
                     /translation="MEDLLDILPKTLSKQLEKLGDMLEDVEEIRIRVNRPLEITSKGIP
                     HFLRYTPTESDAEQLINRLANFSFYALEEELKKGYVTISGGHRVGFAGKVILENGQVKA
                     IRYFSSFNIRIAREKIGTADPYLFALHNGRWLSAMIIGAPQTGKTTFLRDIARLISSGI
                     PERGISPAKVGIVDERSEIAGCVHGIPQLHFGPRVDVLDACPKAEGMMMLIRSMSPDVI
                     VVDEIGREEDAAAIMEAVNAGISLVMTTHGENFRDIQKRPILKKILESYAFDRFLELSR
                     GSRPGRVTAVRDAEGNIIRTGEGVSRA"
     CDS             13099..13614
                     /locus_tag="ctg180_15"
                     /transl_table=11
                     /translation="VLKLFGAALIVLATSFIGFEAAKRLSERPRQLRIFQNALQALEVE
                     IMYGHTPLHEAARKLSGQLPDPAAAFFRSFASQLTTLETTVKEAWEKSLDGIWKLTVLK
                     ENEYEVLRQLGENLGKHDRYTEQKQLLLALSHLEREEKEAHERQLRYEKMAKSLGVLTG
                     LLIAILLI"
     CDS             13645..13848
                     /locus_tag="ctg180_16"
                     /transl_table=11
                     /translation="MGIDVDIIFKIAGVGIVVAFLHTILDQVGKKEYAQWVTLLGFLYI
                     LFLVASIVGDLFSKIKTVFLFQ"
     CDS             13898..14272
                     /locus_tag="ctg180_17"
                     /transl_table=11
                     /translation="VALITTFLALILKEQKPNFAFLLTLFAGCFIFLFLVDKIYEIIHL
                     LQKIAQKGNVDTMYIETILKIIGVAYIADFAANITKDAGQGALAAKVELAGKIIILTMA
                     IPILTVLIETIVNLVPRAGS"
ORIGIN
        1 cagcagaatg aactggaaat tgacatccac tttggattta aacttattat acgaggaggg
       61 gggacatgca aacggttgat tttacagtaa aaaatcatgt cggctggctg acgctgaacc
      121 gtccggataa actcaatgct ttgaatgaaa ccatgaaccg ggaaatcatg gacgttttaa
      181 cagcagctga acaagatccg caaatacgtg cactggtcct caccggtgca ggccgggcct
      241 tctgttccgg ggaggatttg ggcagtttaa acgaacaggc cgatcacggt gaaatcatcc
      301 ggaaacgcta catcccgatg gtaaagaaaa tcgcggcttt tgaaaaaccg ctcattgccg
      361 ccgtgaacgg gccggcggcg ggcgcaggct tcagcctctg cctggcgtgt gatttccgga
      421 tcgcatccga acaggccact tttttaaacg cgtttattca tatcgggctt gtgccggata
      481 ccggaaatcc ctatttcctg ccaagaattg caggctacgc caaagcgttg gaactctctt
      541 gcttagggga gaaaatcagt gcaccggaag ccatggagta cgggctttta acgaaagtgg
      601 ttccagcctg ccatctggaa aaggaaacac agcattttgc tgaaaggctt gctgcaatgc
      661 cgacaaaagc aatcggcctc attaagcggt acatgcaaaa aagctttgaa agcacattgg
      721 atgaaatgct cgaaaaagaa gcatacgccc agcggattgc agggcaaaca gccgaccatc
      781 aggaaggggt ccgggcattt tttgaaaaaa gaaaacctga atacaaaggc aattaaacag
      841 aaagggtgaa catgaatgcc agtaacaaaa gaagcggcag catttcctgc tgaaatgaaa
      901 cggagcgcgt ataaaatggt gatcaacgga gaaccggtgg atgcagccgg ccgcgaaacg
      961 ttccacgtct ataatcctgc aactggcgaa ccaatcgcca cggtgccgaa agcggattac
     1021 gcggatgccg accgggccgt tgaggcggcg cgccatgctt ttgaacacgg aaaatggagg
     1081 cgttatccgg ttggaaaacg ggcgcgcgtc ctgaacaaaa ttgcctccat tatgcgcagc
     1141 cgttttgatg cgcttgttga aatggaaatt ttaaatactg gaaagacgac tgagacggca
     1201 aaggggcagg tgatgcaggc cattgaagat ttcgagtttt tcgcaggagc gattgtcggg
     1261 catcgcggcg ctgtgaacca tgttcccggc cagttcttta actataccca aaaagaaccg
     1321 gttggggtcg ctgcccagat cattccatgg aattacccgc tcatgatggc tgcgtggaaa
     1381 attgccccgg cgatcgcagc aggatgctct gttgtggtaa agccggcaag ccttacgccg
     1441 attacagcca ttttactggc tgaaatctgc catgaggccg gtgttccggc aggcgttgtg
     1501 aacgtgatta ccgggccggg ggcgaaaatc gggtcttatt tggcgaagca tgaaggggtc
     1561 gataaaatcg cttttaccgg ggaaacttcc accggaaaag agatcatggc aaatgcctcg
     1621 gaaacattga aaagagtcac gctggaactt ggcggaaaat ctccgaatct cgtatttcgg
     1681 gatgccgata tcgatgccgc cgtcaatggc gccctgtacg gcatcttcta taataccggg
     1741 caatcgtgcg aagcgagatc ccgtcttttc ctgcaggaag aaatttacga tgcgtttatg
     1801 gagaaatttg tggccaaaac gaaaaaactg gtgctcggtg acccgttttc acctgcctct
     1861 catatcgggg cgatcatcag caaagggcag ctggaaacca tccaccgcta tgtcgaagaa
     1921 gcaaagcagg ccggcgcaac catcgtgaca ggcggaaaac cggctaaagt ggaagggttt
     1981 gaaaatggtt actggtatga accgaccatt atcacaaacg tcaccaatga cagcaaaatt
     2041 gcccaggaag aaatttttgg gccggttgtg gtggtgatgc cttttaaaga ggagaaggaa
     2101 gccgtaaaac ttgcaaatgc gacgaagtac ggcctggctt caagcatctg ggcaaaagac
     2161 cagggcctga ttaagcgggt cgcggacagc atccaggcag gcattgtcat ggtcaacagc
     2221 ccgttctccg catttccggg gacgccgttc ggcggatata aacaatccgg tttcgggcgc
     2281 gaattaagct tcgaatgcct cgatttatac agcgaaacca aaagtgtgct cacttatgca
     2341 ggggcaaaac ctttaaaccc gtttcaattg taagcttccg gcccaataaa ggcgctcatt
     2401 gcggcacgtg cagtgaaacg gatccggcgg ggcaggatgg acaaataaga agcggacgca
     2461 ttctttcggg atgggttcgc ttcttttaaa aatcatcgca aaagatagaa aatttgaaga
     2521 ggaagtggta tgatggcgga aacattggtt gtcattggtt caggggtaat ggggcgcggc
     2581 atcgcttatg cgggcgcact cggcggtttc aaagtcaggc tggtagatgt ccggcctgac
     2641 atcctgcatc aagcggaaaa cataatcgga tccgtcatgg aaaaagggct ggcgaggggg
     2701 aaaatcaacg gggcagacgc tgaaaggata aaggcaaata tcgaatatac cgttgatttg
     2761 ccggcagtag ccggttctgc agatgtgatc atcgaggcag tgccggaaaa aatggaaata
     2821 aaaaaagaag tgtttgaaaa aatggacagg tttgcgcctg ccggttgcat ccttgcgacc
     2881 aatacatcca ccatgagccc gactgaaatc ggttctttta ccacccgccc cgcatctgtc
     2941 attgccatgc attttttcaa tccggtgcat aaaatgccgc ttgtcgagat catcaggggg
     3001 cttgaaacaa gcgatgaaac ggttcaacgg gctgaaaaag cagcggaaaa aatggggaaa
     3061 gaaacagtga tcgtgaatga atttcccggc tttgttacaa gcagaatcag ctgtttggtt
     3121 ggaaatgaag cgttctgcat gctgcaggaa ggggtgggga cagcggaaga aatcgataaa
     3181 gccatcaaac tcggcttgaa ttttccgatg gggccgtttg aattggcgga tctggtcggg
     3241 ttggatgcaa ggctaaacaa tttgcgccac ttgcatgaaa agcttggcga aaagtaccgg
     3301 ccggcgcctt tactggaaaa gtatgtgaaa gcgggccggc ttgggcggaa aacaggcaag
     3361 ggcgtatatg attacacaac ggttgaagga gaatgaagat gagagacgtc gtcatcgtgg
     3421 atgcggtcag aacaccgatt gggcgatata aaggcgcatt aaaatcagta aggccggacg
     3481 atctggcggc aagtgccatc aaggcgttgc tcgcccgcca tcccgaagtc ccctggaacg
     3541 aaatcgaaga agtcattctc ggaaatgcga acggcgctgg cgaagaaaac cggaatgtcg
     3601 caagaatggc tgcactgctc gccgggcttc cggtcgaaac cgccggcaca accgttaacc
     3661 gcttatgcgg atcaggcctc gatgctgtca atattgcagc gaaagcgatt atggctggtg
     3721 acggggacat ctatattgcc ggcgggacgg agagcatgac aagggcgcct tttgtcatgg
     3781 caaagccgga aaacggctac ccgaggggaa atctggaaat gtttgacaca acgatcggat
     3841 ggagatttgt aaatgaaaaa ttaaagaaaa tgtacgggac agacagcatg ccggaaacag
     3901 cggaaaatgt cgcaaagcaa ttccacatca gccgggaagc gcaggatgcc tttgctttta
     3961 cgagccaaat gagggcgaaa gcggccatgg aagcaaaccg ctttcaagat gaaatcgtgc
     4021 ctgtcgtgta tacggatcag aagggggaat ccgtatctgt catccgggat gaacatcccc
     4081 gccccgatac tacgccggaa aaactggcaa ggttgaaacc gctttttgcg ggaggcacgg
     4141 tgactgccgg aaattcatcc ggcatcaatg acggggcgtc tgccgtgcta ttgatgagcg
     4201 cggaaaaagc ggtccaattg ggcatcaaac cgatggcccg gtttgccgcc agcgcaacgg
     4261 cagggctgga accaaggctc atggggctgg gcccggtgta tgcaacgaga aaagcattaa
     4321 agcgttccgg attcaatatt tcggatattg atcttgtaga gttaaatgag gcctttgctt
     4381 cccagtccat tgcatgcatc cggcagctgg agctggacag tgatattgtc aatgtaaacg
     4441 gaggggcgat tgcgttcggg catccgctgg gggcaagcgg cgcgagaatt ttaacaacgc
     4501 tcgtccacga gatgcaaaaa cgaaaggcaa aacgggggct cgctacgatg tgtatcgggg
     4561 tgggccaggg gattgcaacc gttatcgaaa aaatttaaaa tgggggaaag acatctttgg
     4621 cagagacaag gagcttataa atggaaaaaa cgttaaatac gcgttcgatg atttttacgc
     4681 tgtatggcga ttacatccgc cattacggaa gcgaaatttg gattggcagt ttaattaaat
     4741 tgttggaagc gttcggccac catgagcaat ctgtccgcgc cgccatttcc cgcatgagca
     4801 aacaaggctg ggtggaaagc cgcaaagaag gaaacaatag ttactattct ttgactgaac
     4861 gcggtgtcaa acggatgaac gaggccgccg ggcggatttt taaactgaac ccgggcaaat
     4921 gggacggcaa atggcggttt tttctgtata cgatacccga aaaaaagcgg aacatcaggg
     4981 atgaactgag aaaagaactg gtgtggagcg gctttggcct cctgttaaac agtgtctggc
     5041 ttacgccgaa tgatttgctg gatgaaatga aagggattat cgacaaatac gggatcaatg
     5101 aatatgtcaa aatcttcact gccgaaaacg tatggggcaa atccgacaaa gaacttgtgc
     5161 atgaattatg ggatattgat tatatgaacg accgttatga agattttatg gcccattacc
     5221 gggaaaaata tgaaagcgtc aaagaaaaga tgaaaagagg ggaaatgacc aaccaggact
     5281 gctttgtcga acggacgctg cttgttcata attaccggaa actattgttt gtggatcccg
     5341 gtttgccgga agaactgctg cctgaaaagt ggaaagggga agaagcagcc gcgcttttcc
     5401 gggactatta ccggatcctt gccaaaccgg caaatgattt ttttgaagac attttttccg
     5461 aaggatacgg cacttttcag aaaagcaaac attatgatgt gtttgaccat cctcttataa
     5521 ctgaaaaagc ataaccggat ccgtgcgcag aaaggagcga taaagtggca aatccggtaa
     5581 ctgaaatgct gggcatcaaa tttccggttt ttcagggcgg gatgggtaat atcagtgatc
     5641 ctgcccttgc tgcaagtgtt tccaacgccg gcgggctggg aacgattggc gccggaacac
     5701 tgcctgtagc ggaaatcgaa aaaagaatgg acaaaatgcg cagcctggcc gcttccccct
     5761 gctgcgttaa tattgccatt tcggttcatc caaacgcgag cgaagtaatc cggttagcca
     5821 ttgaaaagaa gattccggtt gtttccttat ctgccggcaa cccttcaaaa tatatcccgg
     5881 ttttgcatca aaacggcata aaagtgattt gtgtctcctc cactgtccgc caggcgaaaa
     5941 aagcggaagc agcgggggct gacatcattg tatgcgaagg atacgaggca gcagggatca
     6001 atgctgccaa tgaaagcacg acaatggtgc tcgttccgca gattgtaaaa gcggtcagca
     6061 ttccggttgt cgctgcggga gggattgcag acggcaaagg tttggcggcg gcactttcgc
     6121 tcggggcata cggcgtgcaa atggggacga gattcatcgc gacaaaagaa gcgcagtttc
     6181 accctgtata taagaacgct gtgattgaag caacagatga agcgacgatg atcatcggaa
     6241 ggccctacca aatgttgcgc agagtgttca aaaatgtgta cgcaggctat ctccgcgaac
     6301 tggaagaaag tggtgcggat ccgggccgct ttaaaaagct gacaagcgaa gcccatcatg
     6361 aaaggggagc gcttcaaggc gatatggaac acggttttat aaacgggggc caaattgccg
     6421 gccttattga ggactgcccg tctgttgccc aattattaga agaaatggta aaagaagcac
     6481 gggctgtgct aaccaggagc atggcgcggt tataatcccg taagaactct ttgttctaat
     6541 tcctttcctt atgcgctaaa ataataaaaa agcatttttt tcatctttcg ttcaagcggg
     6601 gcatcctgcc aacattccgc attttttctg accaacaaac cgaaacgccc ggtgcaaatc
     6661 caagggtgga tttccatgga gattgacgcg gtgttttccg gcggaggcat aaaaggcctt
     6721 gcgctcatcg gggcattgga agttttggaa aaaaagggat ttacgtttaa acggctggcc
     6781 ggcacaagcg tcggctccgt ttttgcaggg ctgcgggctg caggctatac aagcggcgaa
     6841 atgaagcaaa tgcttgcgga aacagacacg gccgcgtttc ttgaccagcg aaaaccgctg
     6901 ctgccggtgc cgtttgcgaa atggctgctg ctgtattggc ggctcgggtt gtacaggggc
     6961 accgcgtttg aggaatggat cggggaaaaa ctcgcatcta aaggtgtgta cacgttcaaa
     7021 gatgttccaa aaggctccct ttatttcacg gcatccgatc ttacccataa ccggcttgtt
     7081 gttttgccgg atgacctgga acgttacggg gttccatggc aaacctttcc ggtggcaaag
     7141 gccattcgga tgagctgcag cattccatat tttttcgaac cggtacggtt gcgctcgctg
     7201 gaaggcacaa gcctcattgt agacggcggg gtattaagca attttccgat gtggttgttt
     7261 gtcaaaccgg aagaaaaaaa ggcgcggccg gtgctcggca ttacgctcag cccgaaacaa
     7321 ccggaagagc cggatgtgga gataaaaaat gcgatccagc tgttcgatgc cctgttcaag
     7381 acgatgaaag acgcccatga tgcccgctat atttcaagaa aactggaaaa agacattatt
     7441 tttatcgctg tagatggcgt gactgctaca gattttcagc tttccgccgc acaaaaagca
     7501 gccttaatcg aggcgggtcg gaaaaaaaca gaaacgtttc tgaaaacgtg gtcctattaa
     7561 taaaaaagaa tcgagcttag tagacagctc gatttttctt tttgcccttt ttgccttcaa
     7621 tcacggttaa ctggacattg gattttttgc gcagcggccg ttttgaaaat ttaaccgtgt
     7681 ggacagtatg gaccttcata ttcctttttt tcattctttt cctggatttg cgggcggctt
     7741 ttaaaaatgc tttttgttcc tggttggaaa cattcgtgct tctcttgagc aggaaacgta
     7801 tgccagccaa aagcactgcc gcaaaaatga aggctatcaa cacccttttc aagaatacaa
     7861 ccggctcatg aaacaaagag gaacccaggc cgaccagggc caaaagaaaa atgccggcga
     7921 tgatccattg acgcgtcttc aacaaaagcc acctcctcat gttttcccaa ccattttttc
     7981 catcattcta tcagtttata cggatccggc cgtttttatt ttgaggttga ttccccgtcg
     8041 cacaaacaag cttgtgatag taaatgtatt cccatgcgct ggaaatttca aacgccgttt
     8101 ttaacgggcg gcagaatccg tatcacccga ttccagttca agcagcgcct gaaaggagga
     8161 aatcgcgact tcaatttgct tgtcatccgg ctcttttgtc gttaacagct gcagccacag
     8221 gcccggatag ccaagatact tcagaaccgg aatatggcgg actttattgg tcagctgaag
     8281 gacttcaaac gccgtgccga gcacgaccgg aatgagcaaa atccggtcgg tgatgcggag
     8341 ccagagcgga tctgtcggga caagcgtata aatcaggacg ctcacaatca cggtaaacag
     8401 aataaaactg ctgccgcacc ggtaatgcag cctcgattgc gagcggacgt tttcaacggt
     8461 cagggcaagc ccgttttcaa atgtattgat gactttatgt tcagccccgt ggtattggaa
     8521 tacccgcttg ataaacggcg ttaaagaaat caaataaata tacgaaagca cgagcagcag
     8581 tttaaacgcg ccttcaatga gaatttgcgc ggcatccccg ggaaaaaacg gccttgccag
     8641 ttctgccaga aaaacgggaa taagcgtcat gaaaaatttg gcaaacaaaa aggacaagac
     8701 gccggcagca gccacgccga gcaccacggt tgtttttgcg ggggctgctt ccttccgttt
     8761 ttcgtcttct tccgggtcaa catcataccg ctcgcttgca aaattcaaat gctttgctcc
     8821 gtttgcggat gattcaatga tggcaatgat cccacgcaaa aacgggattt ttttcaattt
     8881 ttggacggac gggcgcgtct cttttggcag ataaaagaag tcgatccggt tgtttttgcg
     8941 gcggatggca gtgaccgaat gccgctttcc gccgaacata accccttcca cgactgcctg
     9001 gccgccataa actggttttg tcaatttctt ttcccccaaa cctgaacttc aaatgcttct
     9061 ttcccgttta acctgaaaac ggagtggatt tccgaaacga tattcactct tattttacta
     9121 aatcatttta aatacgacta ggggaaagac ttgtgggaaa gataagaaag aaaagatgca
     9181 tgccgtcaca tgtgaaggag tggaaaatat ggaaaatggc agcaaagtat taaaaaacca
     9241 ggagcattcc atgacctttt ttcaaatggt gcttgtgacc ggatttgcgg gcgggatcat
     9301 ttggagcctg gttgcttatt tatacttttc ttttcatttt acggcgattg aaccgaatgt
     9361 cctgcttgaa ccatttacag taggatcctg gcgcaatatg tggatcggaa aaatcatttc
     9421 catattggta tacggattgc tttctaccgg ctgtgccctt gtctattatc ttttctttaa
     9481 aaaattgaaa tcgatgtggg tcggcgcgat atacgggctt tgcctgtgcg cagtcgtcct
     9541 cattgtgctg aatccgattt ttcccggcat gaaacctttt ttaaaactgg atgccaatac
     9601 gatcattacc tgctgttgca tttacattct ctacggcgtg tttatcggtt attcgatttc
     9661 atttgagtat gaaagaagcc gggtttttaa aagaaaactg gagaggcaga cgaacccgct
     9721 gccgtaaatc gatccgggcg ggaggaacgc cccggattca ggcgcaagca tgcggccgaa
     9781 aagttaaaaa atagaaattt tcttcaattt atggtaaaat gggcacgtta aatatgggaa
     9841 aaaggtgctt gaaatgaaaa aatacctcgt attaaacggc ccaaatctga atttgctcgg
     9901 gcaaagggaa cccggcactt acgggaaaga ttcgttaaaa accctgatgg cgcgcatgga
     9961 agcggcggcc cgaaagcacg gcgtcgccat cggttttttt caatccaacc atgaaggcgc
    10021 cctgattgac aagctgcacg ctgccgggga tgaaggcttt gcagggatta ttttcaatcc
    10081 gggcgcgttc acgcattaca gctatgcttt gcgggacgcg atcagtgcca tccgcctacc
    10141 ggtgattgaa gttcatattt cgaacatcca tgcccgcgag gaattccgcc accattctgt
    10201 aacggcggct gttgcgcagg ggcaaattgc aggcttcggg ctgtacggct atgagcttgc
    10261 cctcatggcc ttgcttgagg cagaaaaggg agaggaagaa agatgttaaa actggagaaa
    10321 ctgagagaaa catttccgca ggccggtatt gacggcttgc tcattacaag cccgtataac
    10381 cgccgctata tgtccaattt tacggggact accgggattg tccttatatc cggggaagcg
    10441 gcaaaattta ttacggactt ccgctatgtc gagcaggcat cgaaagagtg tgaaggctac
    10501 gaaatcgtcc agcatcaggg gccggtggaa caggaagtgg ccaaacaggt ggaagcaatg
    10561 gggatcaaac ggctcgggtt tgagcaggac catatgagct atgcgctttt taaaacgtat
    10621 gaagggctgc tcgatgcgga actggtcccg gtttccggcc ttgttgaaaa tttgcgcttg
    10681 atcaaaacag atgcggaaat taagatatta aaagaggctg cggatattgc ggatgttgcc
    10741 tttaaacata tccttgactt cttaaaaccg ggcgtcacgg aattggaagt ttccaatgaa
    10801 ctggaatttt tcatgaggaa atgcggcgcg actgcttctt catttgatac cattgtcgca
    10861 tccggcctcc gctctgccat gccgcacggg gtggcgacgg acaaggtgat cgaaaaaggc
    10921 gatttggtta cgatggatta cggcgcgctc tataaaggct attgttcgga tattacaagg
    10981 acggttgcgg tcggcgagcc ttccgggcaa ttgaagaaaa tctacaatat tgtgctggaa
    11041 tcgcagctgc ttgccgtcca aaacatcaaa ccgggcatgt ccggtattga agcagacgcc
    11101 atttcccgcg attatatcgc ccggaaaggt tacggcgatg cgttcggcca ttcccttggg
    11161 cacgggatcg gccttgaaat ccacgaaggc ccgaatcttt ccatgcgctc gggctatact
    11221 ttggaaccgg gcatggttgt caccatcgaa ccgggcattt atgtgccggg tgtcggcggc
    11281 gtccggattg aagacgatac ggtgattacc gaaaattcga atgaattgct gacgcattcc
    11341 gcaaaagaac tgattatatt ataatagtta cagccctcaa caggggatcg aatgaacatg
    11401 taggaggaaa aatatgattt cagtaaacga ttttcgcacc ggcttaacga ttgaagtgga
    11461 cggcggcatc tggcgcgtcc tcgatttcca gcatgttaag ccgggaaaag gcgccgcttt
    11521 tgtgcgctcg aagcttcgca atttgcgtac cggcgctatc caggaaaaaa cgttccgtgc
    11581 cggcgaaaaa gttgaaaggg cacagatcga caaccggaga atgcagtatt tatatgcaaa
    11641 cggcgaccag cacgtattta tggatacgga aacgtatgaa caaatcgagc tgagtagcgc
    11701 ccaaattaaa gatgagctgc aatacttgct ggaaaacatg gaagtgcaaa tgatcatgta
    11761 ccagggagaa acgctcggca ttgaactccc gaatacggtc acgctgacag ttacccatac
    11821 agaaccgggg gtaaagggcg atacggcaac aggcgggtcc aaaccggcca cgcttgaaac
    11881 cggcctgacg gtacaggtgc ctttctttgt caatgaaggc gataaattga tcatcaatac
    11941 aacggacggt tcatacgtgt cccgtgcctg atttctttga aaaaagcttg gcgtcccaaa
    12001 cggcgccaag cttttttgct tttccggcaa gagacaggca aaaataagtt tacataatca
    12061 tgttataaat aacttaaact ttcagcatct gcctcgcttc cttgtcatag ttttcaaacc
    12121 cggcgaatag attgtactat ccatgaacca aactgtatgt tttgaaagca gggatgaaga
    12181 tggaagattt gctggacatt ttgccgaaaa ccttatccaa acagctggaa aagttggggg
    12241 acatgctcga agatgtggaa gaaatccgca tccgcgtaaa ccgcccgctt gaaattactt
    12301 caaaaggaat cccgcatttt ttgcgctata cgccaacgga gagcgatgct gagcagttga
    12361 tcaaccggct tgcgaatttc tctttttacg cccttgaaga agagctgaaa aagggatacg
    12421 tcacgatcag cggcgggcat cgtgtcggat tcgcggggaa agtcattctt gaaaatggac
    12481 aagtaaaggc gatccgctat ttttcatctt ttaatatccg gattgcccgg gaaaaaatcg
    12541 ggactgcgga tccttatctt ttcgcccttc acaacgggcg ctggctgtcc gcgatgatca
    12601 tcggggcgcc ccagaccgga aaaacgactt ttttaaggga tatcgcgcgg ctgatttcaa
    12661 gcggcatccc ggaacgcggg atttcgcctg ccaaagtggg gattgtcgac gaacggtctg
    12721 aaattgccgg ctgcgtccac ggcatcccgc aactccattt cgggccaagg gtcgatgtgc
    12781 tggatgcctg tccgaaagcg gaagggatga tgatgctgat ccggtcgatg agcccggatg
    12841 tcattgtcgt ggatgagatc ggccgcgaag aagatgcggc ggcgattatg gaggcggtaa
    12901 atgcgggcat ttcgctcgtc atgacaacgc acggggaaaa cttccgggat atccaaaaac
    12961 gcccgatttt aaagaaaatc ctcgaatcgt atgcgtttga ccgctttctc gaactgtcac
    13021 gggggagccg gccgggaagg gtaacagcgg tccgcgatgc ggaagggaac atcatccgta
    13081 ccggtgaagg tgtttcccgt gcttaaactt tttggagcag cactgattgt gctcgccacc
    13141 agtttcatcg gctttgaggc agcaaaacgg ttaagcgaac gcccccgcca gctgagaatt
    13201 tttcaaaacg cgcttcaggc actagaagtg gaaatcatgt acgggcatac cccgctgcat
    13261 gaagcggcaa gaaaactatc aggccagctc ccggatccgg ctgccgcctt cttccgttcc
    13321 tttgccagcc agttgaccac attggaaaca acggtcaaag aagcgtggga aaaaagcctt
    13381 gacggaattt ggaaactgac ggtcctgaaa gaaaacgagt atgaagtatt gcggcagctc
    13441 ggggaaaacc tgggcaaaca tgaccgctat accgagcaaa agcagctgct cctggccctt
    13501 tcacatttag aaagggaaga aaaagaagcg cacgaaaggc agctccgcta tgaaaaaatg
    13561 gcaaaaagcc ttggcgtcct cacgggttta ctgatcgcta ttttactgat ctaaagtctc
    13621 acggatcata ttgggggaaa agcaatgggc attgatgtgg acatcatttt taaaattgcc
    13681 ggggtcggga ttgttgtggc gtttctccac acgattctgg accaggtcgg caaaaaagaa
    13741 tatgcgcaat gggtcacgct tctcggtttt ctttacattt tgtttttagt ggcatccatc
    13801 gtaggggatt tgttttccaa aatcaaaacg gtctttcttt ttcaataagc cgggaaaaaa
    13861 ggggggattt cccattgaaa ttttgcaaat tgcgggtgtg gcgctcatca cgactttcct
    13921 tgcgctcata ttaaaagagc agaaaccgaa ttttgccttt ttgctgacgc tttttgccgg
    13981 ctgttttatc tttctttttc tggtggacaa gatatacgaa atcatccacc tgctgcaaaa
    14041 aattgcccaa aaagggaatg tagacacgat gtatatcgaa acgatcctga aaatcatcgg
    14101 cgtcgcttat attgccgatt ttgcagccaa tattacaaaa gatgccgggc agggggcact
    14161 tgcggcaaag gtggagctgg ccggcaaaat cattattttg acaatggcca tccccattct
    14221 taccgtgctg atcgaaacga ttgtcaatct cgttccgcgt gcagggagtt gaggatatgg
    14281 ggcacaaaaa aatatacatc gcacttttca ttctgtttgc cttctgtttc ttcgcacagt
    14341 cggcatccgc cgcttcggaa aatacggaca aacaggagaa tattccggaa aaaatggtcg
    14401 atgaacaatt gaatcaattg gacttatcag aactgaaaaa ctactgggac gacattgtca
    14461 gcaaatacgg cggatacttg ccggaaagcc agaaagggag ccttatggat tttatgaaag
    14521 gcgagaagca tttttccttg caagcctggc tgaaagggct gctttcgtat attttccagg
    14581 agctgctgat caacgcaa
//
