LOCUS       gnlProkkaHFLGGCGD_18    1692 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HFLGGCGD_18.
ACCESSION   gnlProkkaHFLGGCGD_18
VERSION     gnlProkkaHFLGGCGD_18
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 03:31:17
            Original ID  :: gnl|Prokka|HFLGGCGD_18
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 1692
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..1692
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:1690]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..1690
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..1692
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..1692
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             2..1690
                     /NRPS_PKS="Domain: AMP-binding (30-418). E-value: 9e-107.
                     Score: 349.0. Matches aSDomain:
                     nrpspksdomains_ctg18_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (523-563). E-value: 4.8e-17. Score:
                     53.8. Matches aSDomain: nrpspksdomains_ctg18_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     350.4; E-value: 2.3e-106)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_1"
                     /sec_met_domain="AMP-binding (E-value: 5e-116, bitscore:
                     373.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.8e-10, bitscore:
                     27.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTETEKQALLEAWKGKALPVPTDKTVHQLFEETAQRHKDRPAVT
                     YNGQSWTYGELNAKANRLARILMDCGISPDDRVGVLTKPSLEMSAAVLGVLKAGAAFVP
                     IDPDYPDQRIEYILQDSGAKLLLKQEGISVPDSYTGDVILLDGSRTILSLPLDENDEGN
                     PETAVTAENLAYMIYTSGTTGQPKGVMVEHHALVNLCFWHHDAFSMTAEDRSAKYAGFG
                     FDASIWEMFPTWTIGAELHVIEEAIRLDIVRLNDYFETNGVTITFLPTQLAEQFMELEN
                     TSLRVLLTGGDKLKRAVKKPYTLVNNYGPTENTVVATSAEIHPEEGSLSIGRAIANTRV
                     YILGEGNQVQPEGVAGELCVAGRGLARGYLNREDETAKRFVADPFVPGERMYRTGDLVK
                     WTGGGIEYIGRIDQQVKVRGYRIELSEIEVQLAQLSEVQDAAVTAVKDKGGNTAIAAYV
                     TPETADIEALKSTLKETLPDYMIPAFWVTLNELPVTANGKVDRKALPEPDIEAGSGEYK
                     APTTDMEELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRL"
     aSDomain        92..1255
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_1_AMP-binding.1"
                     /evalue="9.00E-107"
                     /label="ctg18_1_AMP-binding.1"
                     /locus_tag="ctg18_1"
                     /protein_end="418"
                     /protein_start="30"
                     /score="349.0"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="FEETAQRHKDRPAVTYNGQSWTYGELNAKANRLARILMDCGISPD
                     DRVGVLTKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKLLLKQEGISV
                     PDSYTGDVILLDGSRTILSLPLDENDEGNPETAVTAENLAYMIYTSGTTGQPKGVMVEH
                     HALVNLCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVIEEAIRLDIV
                     RLNDYFETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYTLVNNYGPT
                     ENTVVATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYL
                     NREDETAKRFVADPFVPGERMYRTGDLVKWTGGGIEYIGRIDQQVKVR"
     aSModule        92..1690
                     /complete
                     /domains="nrpspksdomains_ctg18_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg18_1_PCP.1"
                     /locus_tags="ctg18_1"
                     /monomer_pairings="Leu -> Leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       278..319
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0001"
                     /evalue="4.90E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg18_1"
                     /protein_end="106"
                     /protein_start="92"
                     /score="19.6"
                     /tool="antismash"
                     /translation="LGVLKAGAAFVPID"
     CDS_motif       521..580
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0002"
                     /evalue="3.70E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg18_1"
                     /protein_end="193"
                     /protein_start="173"
                     /score="34.7"
                     /tool="antismash"
                     /translation="AYMIYTSGTTGQPKGVMVEH"
     CDS_motif       920..949
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0003"
                     /evalue="2.90E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg18_1"
                     /protein_end="316"
                     /protein_start="306"
                     /score="10.3"
                     /tool="antismash"
                     /translation="NYGPTENTVV"
     CDS_motif       1052..1141
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0004"
                     /evalue="2.10E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg18_1"
                     /protein_end="380"
                     /protein_start="350"
                     /score="52.0"
                     /tool="antismash"
                     /translation="PEGVAGELCVAGRGLARGYLNREDETAKRF"
     CDS_motif       1220..1285
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0005"
                     /evalue="1.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg18_1"
                     /protein_end="428"
                     /protein_start="406"
                     /score="36.7"
                     /tool="antismash"
                     /translation="YIGRIDQQVKVRGYRIELSEIE"
     aSDomain        1571..1690
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_1_PCP.1"
                     /evalue="4.80E-17"
                     /label="ctg18_1_PCP.1"
                     /locus_tag="ctg18_1"
                     /protein_end="563"
                     /protein_start="523"
                     /score="53.8"
                     /tool="antismash"
                     /translation="EELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRL"
ORIGIN
        1 actggtcacc gagacagaaa agcaagcgct tcttgaggca tggaagggca aagcgctgcc
       61 tgtgccgaca gacaaaacgg ttcatcagct attcgaagag actgcccagc gccacaaaga
      121 ccgcccggct gtcacataca acggccagtc ttggacgtac ggcgagctga atgcgaaggc
      181 aaaccgtctc gcgcggattc tgatggactg cggcatcagc ccggatgacc gcgtcggcgt
      241 tctcacgaag ccgtcgcttg aaatgtccgc cgcggtgctc ggcgtcttga aagccggagc
      301 ggcgtttgtg ccgattgatc ctgactatcc ggatcagcgg attgagtata ttttacagga
      361 cagcggcgcg aagcttctct tgaaacagga aggcatttca gtgccggaca gctatacggg
      421 agatgtcatt cttctcgacg gaagccgcac gattctaagc ctgccgcttg atgaaaacga
      481 cgagggaaat ccagaaaccg ctgtaaccgc ggagaacttg gcgtacatga tttacacgtc
      541 tggaacgacc ggacagccga agggtgtcat ggtcgagcac catgcgcttg tgaacctgtg
      601 cttctggcac cacgacgcgt tcagcatgac agcggaggac cgcagtgcga agtacgcggg
      661 ctttgggttc gacgcttcca tttgggagat gttcccgacc tggacgatcg gtgccgaact
      721 tcacgtcatt gaggaagcga tccgcctcga tatcgtccgc ctgaacgatt attttgaaac
      781 gaacggcgta acgatcacgt tcctgccgac acagcttgcg gaacagttca tggagcttga
      841 gaacacatca cttcgcgtcc tcttgaccgg aggagacaag ctgaagcggg cagtgaaaaa
      901 gccgtacaca ctcgtcaaca actacgggcc gacagaaaat acggtcgttg ccacaagcgc
      961 agaaatccat ccggaggaag gctcgctttc catcggaagg gccattgcca atacgagagt
     1021 atacattctc ggcgagggca atcaggtgca gccggaaggc gtagccggag agctttgcgt
     1081 ggcggggcgc ggactggcac gaggctatct gaatcgagaa gacgaaaccg cgaagcggtt
     1141 tgtcgctgat ccgtttgtgc cgggtgagcg catgtaccgc accggcgatt tggtgaaatg
     1201 gacgggcggc ggcatcgaat acatcggccg gatcgaccag caggtcaagg tccgcggcta
     1261 ccggatcgag ctctcagaaa ttgaagtcca gctcgcccag ctttctgagg tgcaggatgc
     1321 ggcggtgaca gctgtcaaag ataaaggcgg caatacagcg atcgcggcgt atgtcacacc
     1381 ggaaacagct gacatagaag cactaaaatc aacactaaag gaaaccctgc cggattacat
     1441 gatcccggcg ttctgggtga cgctgaacga gcttccggtt acggcaaacg gcaaagtcga
     1501 ccgcaaagcc ttgcctgagc cggacatcga agcgggaagc ggagaataca aagcgccgac
     1561 gaccgacatg gaagagctgc ttgccggcat ctggcaggac gtgcttggaa tgtctgaagt
     1621 cggtgtcacc gacaatttct tctcgcttgg cggagattcc atcaaaggaa ttcaaatggc
     1681 gagccgcttg aa
//
