LOCUS       gnlProkkaIKHLGJIB_16   13871 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IKHLGJIB_16.
ACCESSION   gnlProkkaIKHLGJIB_16
VERSION     gnlProkkaIKHLGJIB_16
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 03:39:44
            Original ID  :: gnl|Prokka|IKHLGJIB_16
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 9050
            Orig. end    :: 22921
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13871
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:8871]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8871
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13871
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13871
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(391..1728)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 303.6; E-value:
                     3.1e-92)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_13"
                     /sec_met_domain="Aldedh (E-value: 2.2e-101, bitscore:
                     333.0, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQKVKDDIQRVFQLQKKQQKALRASTAEQRKEKLQRFLDSVIAH
                     EEEIIEAIRKDVRKPYHEVKKAEIEGTKKAIRDNMNNLEQWMAPKEVGSSLSPEANGIL
                     MYEPKGVTLILGPWNYPFMLTMAPLAASLAAGNSAIVKLSDFTMNTSNIAAKVIRDAFD
                     EKEVAIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGKSPTI
                     IDSEYDLMDAAKKIAVGKFVNAGQTCIAPDYLFIKKDVQDRFAGILQTVVNAGFMEDDH
                     TPDRSKFTQIVNDRNFNRVKDLFDDAIEKGAEVVFGGVFDASDRTISPTVLKNVTPDMK
                     IMQEEIFAPILPMMNYEDIDEVIDYVNDRDKPLALYVFSKNQDMIDNVLQHTTSGNAAI
                     NDVVVHFSDVNLPFGGVNTSGIGSYHGVYGFKEFSHEKGVFIQASK"
     CDS             1871..3013
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 41.4; E-value: 3.5e-12)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg15_14"
                     /transl_table=11
                     /translation="MPESAEAQVKQALLALLEERDMQHITMKEIAERAKVSRGTLYLYY
                     EDKFSIIEDLIEDMKEGLGKALFDAFSHLDTLHLNKKRQTVHPTLSFVHEHRSFFSVMM
                     NRGHFHRFFKDVFHHDVLLAPIHVNLTPIEREIYGHYRALYTYAIILYWLNEDAAAAPE
                     AISQKVWELVSQKRFYWLFGQAVPGEREKGKPIDRRVVRTREALQQAFLDVLAEKQDYA
                     GITISDITRKSNIRRATFYDHYANKEELLRTMIQRSCAEIIDHLTIASSPNEFSLKEAE
                     KALASLLSALSNMPIVHFLNREWGVPHVIPDMFKALESFYLHQQTDIHAEKKLYAHYVS
                     AMIIGLLLYRLDEGKAHEPEVLAREFLQFLDVKKYKVVLL"
     CDS             complement(3531..5000)
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 71.6; E-value:
                     9.3e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg15_15"
                     /transl_table=11
                     /translation="MKRNFFNLHDLKDSREFYESKPKPIGVFFTYILIALLIACIVFSF
                     YGKKEVILKTTADIQYTKPNSNVTNEVAGKVKTVDIKQVDKVKKGDTLLTLDNTEIQAQ
                     KKAVKADIKDLKEQAALNKTLKKSIENDKNLFSEDDHWGYQDQYLSYEKQSILLESSKE
                     NAKTQQKKLKKQKESIKDSLDKTKNKVKLKLQRISDLQDSIKNNKSFAKQDDKYSSYYN
                     SYQTNKQNVEQQLDDLRKMKDELDKNRFSQQKENLNGQLESLKQDMLVKLSEEKDELNQ
                     SLDEINSSIKSDDSDSDSDNSEETNYKLSIEQLKTNLLNQTSQKQTDLQTTLKSKEDDL
                     KMIDLQLEKYKIKAASDGYVNVLTNISPGDNLQAGTAILTIIPDKEKLKANIYIPSHEI
                     TNINEKDEVRFHIENTNQTIKGVITKISPDSISDQNGQKFYIAESTIEKNKVMNDNGST
                     LHLKNGMQTDVSIIVDSKRYIDYLLEILHLQ"
     CDS             complement(5001..7184)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 302.4; E-value:
                     1.1e-91)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_16"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.2e-44, bitscore:
                     143.3, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 1e-237, bitscore:
                     784.3, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFFNRYHCVRQLDQKDCGAACLSTIAKHYGSKLSLAYIRDIAGTD
                     TQGTSALGMVKAAEQLGFSAKAVRAEHTAFDQSITLPAIAHIIIDQQLLHYVVIHKISK
                     DKIIIADPGKGLVTYQKDDFFKIWTGILILLAPTETYKKQTETSNISADIFRLILQQKS
                     LIIHTFLASFIITIFGILGTFYFQTIIDQILPNGLSNTLHILSIGLLIMYLFKVFLIGF
                     RQYLMILLGQKLSISIMFGYFQHVLTLPMKFFSNRKVGEIISRFTDANKVIDAVVSASL
                     SVILDTIMLIMVGIFLYLQNTTLFLITLAFIPFYILTVWIFIKPYENINNTEMENNAQL
                     TSKIVETLNGIETVKAYNAEYMMSFETEKRFVKYLRSAFKHGVIDNLQSSIKMFLDLAS
                     GALILWIGSTQVMKGTLTIGQLITYNALLTYFLNPLQNIIGLQSKLQSASVASKRLGEI
                     LKLEPELKEKEAQITSTSSITGPLSFNKINFRYGTRRLILKDITLHIQKGEKVAFVGES
                     GSGKSTLTKLLMKFYTAESGEVLINGYHINDIHTNALRESISYIPQESHFIQGSILENL
                     LLGNSGSFTFEEIIEVCKQTNVHDFVNDLPMRYDTLVEENGSNLSGGQKQRLAIARALL
                     RKPNILIMDESTSNLDTTTEQGISKMIYDQTVGITTIIIAHRLSTIMNCDKIFVMENGE
                     IIEYGNHNDLLKKKGKYYELWENQMPSRGMVTI"
     CDS             complement(7280..7432)
                     /locus_tag="ctg15_17"
                     /transl_table=11
                     /translation="MKLFYSYIIAGGLFCISLSYFFHLGVFNLALYLIYINYAFILYKR
                     AKSSK"
     CDS             7577..7795
                     /locus_tag="ctg15_18"
                     /transl_table=11
                     /translation="MNNNLKLERTRANLTQEQLAEKIGVTRQTIGLIEKGKYNPSLQLC
                     LKICIELKVTLNDVFWTYNREEESNEG"
     CDS             7785..8210
                     /locus_tag="ctg15_19"
                     /transl_table=11
                     /translation="MKDERISHIENKIGHESFLLVIALVFVSFILSIMFKIPSTLMTII
                     ILFVGSGYYGLRAMSKGILRVNLKKKKKSSYFLLIVFTFILYMATSILFKIITFPFTTK
                     EFLFQILMYILWLIPFSLIMYTTYKFSNRQQKKELEN"
     CDS             8399..8629
                     /locus_tag="ctg15_20"
                     /transl_table=11
                     /translation="MDTKSIKDVELQALTLEEAEQIDGGSYAKYLGTSVVTGAGAGVVG
                     GVPGVILGAHAGAIAGSVGYLGGSLIAGKWL"
     CDS             8647..8871
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_21"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.1e-09,
                     bitscore: 31.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNNRFSELNVKEMEQIDGGGWRSALGGAFSGALVGASTVGVGG
                     AAVGGPVGGVGGAITGGIVGGIVGGINEW"
     CDS             complement(8986..9807)
                     /NRPS_PKS="Domain: PKS_KR (7-160). E-value: 1.3e-09. Score:
                     30.0. Matches aSDomain: nrpspksdomains_ctg15_22_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     247.1; E-value: 3.1e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_22"
                     /sec_met_domain="adh_short (E-value: 1.5e-33, bitscore:
                     109.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 8.6e-38, bitscore:
                     124.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRLENKTAVITGAATGIGQATAEVFANEGARVMIGDINEDQMKE
                     TVEAIRQNGGQADAFHLDVSDENSVKAFADQIKEACGTIDILFNNAGVDQEGGKVHEYP
                     VDLFDRIIAVDLRGTFLCSKYLIPLMLEKGGSIINTSSMSGRAADLDRSGYNAAKGGIT
                     NLTKAMAIDYARDGIRVNSISPGTIETPLIDKLAGTKEQEMGEKFREANKWVTPLGRLG
                     QPKEMATVALFLASDDSSYVTGEDITADGGIMAYTWPGKMLLDEKWKEETK"
     aSDomain        complement(9328..9786)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg15_22_PKS_KR.1"
                     /evalue="1.30E-09"
                     /label="ctg15_22_PKS_KR.1"
                     /locus_tag="ctg15_22"
                     /protein_end="160"
                     /protein_start="7"
                     /score="30.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAVITGAATGIGQATAEVFANEGARVMIGDINEDQMKETVEAIRQ
                     NGGQADAFHLDVSDENSVKAFADQIKEACGTIDILFNNAGVDQEGGKVHEYPVDLFDRI
                     IAVDLRGTFLCSKYLIPLMLEKGGSIINTSSMSGRAADLDRSGYNAAKG"
     CDS_motif       complement(9712..9780)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg15_22_0001"
                     /evalue="7.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg15_22"
                     /protein_end="32"
                     /protein_start="9"
                     /score="15.4"
                     /tool="antismash"
                     /translation="VITGAATGIGQATAEVFANEGAR"
     CDS             10337..12217
                     /locus_tag="ctg15_23"
                     /transl_table=11
                     /translation="MAKKEFKAESKRLLDMMINSIYTQKEIFLRELISNSSDAIDKIYY
                     KALTDDALTFDKDSYYIKVAADKDARTLTISDTGIGMTKDELEQHLGTIAKSGSLAFKK
                     ENELKDGHDIIGQFGVGFYAAFMVADVVTVISKALGSEEAYKWESAGADGYTIEPCEKD
                     SVGTDIILKIKENTEDDSYDEFLEEYRLKAIIKKYSDFIRYPIKMDTTINKPKEGSENE
                     FEEVQEEQTVNSMVPIWRKNKSELTDEDYEKFYAEKHYGFDKPLTHVHISVDGAVRYNA
                     ILFVPENMPFDYYSKEYEKGLELYSNGVLIMNKCADLLPDHFSFVKGMVDSEDLSLNIS
                     REMLQHDRQLKLIAKNISKKIKSELQSLLKKDREKYETFYKSFGRQLKFGVYNDFGANK
                     DQLKDLLLFYSSKEKKLVSLDEYVSRMPEEQKFIYYATGDSYDRIEKLPQTEMVADKGY
                     EILYFTEDIDEFAIKMLASYQEKEFKSVSSGDLGIDTDEDQKQSEEEESKYKDLFEEMK
                     NILSDKVKNVRISKRLKSHPVCLAADGEVTIEMEKILNAMPDSQNVKAEKVLEINPNHE
                     VFQTLQDAFEQDKEKLSLYTNLLYNQALLIEGLPIQDPVEFTNNICKVMV"
     CDS             complement(12259..13644)
                     /gene_functions="transport (smcogs) SMCOG1169:sugar
                     transport protein (Score: 438.3; E-value: 5e-133)"
                     /gene_kind="transport"
                     /locus_tag="ctg15_24"
                     /transl_table=11
                     /translation="MKKDTRKYMIYFFGALGGLLYGYDTGVISGALLFINNDIPLTTLT
                     EGLVVSMLLLGAIFGSALSGTCSDRWGRRKVVFVLSIIFIIGALACAFSQTIGMLIASR
                     VMLGLAVGGSTALVPVYLSEMAPTKIRGTLGTMNNLMIVTGILLAYIVNYLFTPFEAWR
                     WMVGLAAVPAVLLLIGIAFMPESPRWLVKRGREEEARRIMNITHDPKDIEMELAEMKQG
                     EAEKKETTLSVLKAKWIRPMLLIGVGLAIFQQAVGINTVIYYAPTIFTKAGLGTSASAL
                     GTMGIGILNVIMCITAMILIDRVGRKKLLIWGSVGITLSLAALSGVLLTLGLSASTAWM
                     TVVFLGVYIVFYQATWGPVVWVLMPELFPSKARGAATGFTTLVLSAANLIVSLVFPLML
                     SAMGIAWVFMVFSVICLLSFFFAFYMVPETKGKSLEEIEASLKKRFKKKKSTQNQVLNE
                     RTL"
ORIGIN
        1 tagtaaagaa tagcgaaaat aaatatgatg gccaaaacag ggattgtgcc aatgatcaac
       61 atgaaaaact catattgggc ttctgacatg tgtgtacctg ctgcatcaat gagtggcaac
      121 acaatgaagg tgttaatgaa aatcataatg aaagagaata tagctataat aaatacatca
      181 ataatagagg cggctgcccg aatccaaaat cctgctggtt tttccatgta tcattttact
      241 cctttaaagt tttctgggta ttatacgtta ggggctgcag ggtttggtct cgtagtaaaa
      301 atggtatttt atcactttta atctctttat ttaggtgata taaagataaa aaaagaacct
      361 gcaagatgat gcagattctc ttcgttacga ttatttggag gcttgaataa atacaccctt
      421 ttcgtgagaa aactctttga atccgtatac cccatgatag gagccgattc cgcttgtgtt
      481 gacgccgccg aatggcaggt tgacgtcact gaaatggacg acgacatcat tgatggcggc
      541 atttcctgat gtcgtgtgct gaaggacgtt gtcaatcatg tcttggtttt tgctgaacac
      601 ataaagtgca agcggtttat cgcggtcatt tacgtaatca atgacctcgt cgatgtcttc
      661 atagttcatc attggcagaa tcggtgcgaa gatttcctcc tgcatgattt tcatgtcagg
      721 cgtgacgttt ttcaaaacgg ttggcgagat cgtgcggtcg ctggcatcaa agacgccgcc
      781 gaacaccact tccgcccctt tttcgatggc atcgtcgaac agatctttga cgcggttgaa
      841 gttgcggtca ttgacgatct gcgtaaattt gctgcggtct ggggtatgat catcctccat
      901 aaatccagcg ttgacgactg tttgtaaaat ccccgcaaac ctgtcctgaa cgtctttttt
      961 aatgaacagg taatcaggtg cgatgcaggt ttggccggcg tttacgaatt tcccgacggc
     1021 gatctttttc gctgcgtcca tcagatcgta ttcactgtca ataatcgtcg ggctcttgcc
     1081 gccaagctca agtgtgacag atgccaagtg tttggcagcc gctgtcatga cgattttccc
     1141 gacatttgtg cttccagtga agaaaatatg gtcgaacggc tgatcaagta gttcggttgc
     1201 cacctcaacc tctccttcaa aaatcgcgac ttctttttca tcaaaagcgt ctcttatcac
     1261 tttagcggca atgttgctcg tgttcatcgt gaaatcggac agcttcacaa tcgcgctgtt
     1321 tccggctgcg agagaagcgg caagcggcgc catcgtcagc ataaacggat agttccacgg
     1381 gccgaggatg agtgtgacgc ctttaggctc gtacataaga atcccgtttg cctcagggct
     1441 taacgatgaa ccgacttcct taggcgccat ccattgttcc aggttgttca tattatctct
     1501 gatcgctttt ttcgttcctt cgatttccgc ttttttgacc tcgtgatatg gtttgcggac
     1561 gtctttgcgg atcgcttcaa tgatttcttc ctcatgggcg atgacggaat ctaaaaagcg
     1621 ctgaagcttc tctttgcgct gttccgctgt tgaagcacgc aaggcttttt gctgtttttt
     1681 ctgaagctga aagacacgct ggatgtcgtc ctttactttc tgttccattg taagatcccc
     1741 ctcatttgct ttcttctttt ctcggaccta ttataaggtg gtaccttttt tataagaaag
     1801 acaacggtga accatctata cgttaccgta catatattga acaactgtct aatgattgga
     1861 ggtgtctttt gtgccggaat ctgccgaagc tcaagtgaaa caggcgctgc tggctttatt
     1921 ggaagaaaga gatatgcaac atatcacaat gaaagaaatc gctgaaaggg ccaaagtgag
     1981 ccgtgggacg ctctaccttt attatgagga taagttttca atcattgagg atttaatcga
     2041 agacatgaag gaagggctgg gtaaagcgct ttttgatgct ttcagtcatt tggataccct
     2101 ccacttgaac aaaaaacggc aaacggtgca tccgacgctg tcctttgttc acgagcatcg
     2161 atcctttttt tctgtgatga tgaacagagg gcatttccat cgttttttta aggatgtgtt
     2221 tcaccatgat gtgctgctgg ctccgatcca tgtgaatttg acgccgatcg aacgagaaat
     2281 ttacggacat taccgggcct tgtacacata cgcaattatc ctgtattggc tgaatgagga
     2341 tgcggccgcg gctccggaag ctatcagcca aaaggtatgg gagcttgttt ctcaaaagag
     2401 attttattgg ctgtttggac aagctgtgcc aggagagcga gagaagggca agccaatcga
     2461 caggcgggtg gttcgaacga gagaggcgct ccagcaggca tttctggacg tattggcgga
     2521 gaaacaagac tacgcgggca tcacgatttc ggatattacg cgtaaaagca atatccgccg
     2581 cgcaactttt tatgatcact atgccaataa agaggaattg ctccgaacca tgatacagcg
     2641 atcatgtgcg gagatcattg atcacctgac gattgcctcc agcccgaatg aattttcctt
     2701 aaaggaagcg gagaaggcgc tcgccagtct gctttctgct ttgtcaaata tgcccattgt
     2761 ccattttctc aatcgggaat ggggtgttcc tcatgtgata cctgatatgt tcaaagcact
     2821 ggaatcgttt tatctgcatc agcaaactga tattcacgca gagaaaaagc tttatgccca
     2881 ttatgtatcc gcaatgatta tcgggttgct tttgtatcgg ctggatgaag gaaaggcgca
     2941 tgagccagaa gtgctggcga gggagttttt gcagtttttg gatgtgaaaa agtataaggt
     3001 tgtattgcta taaacgagag aaaccagcca gtggctgaaa tggaaggccg gagagtaact
     3061 tcagtatgtt atgaaaagaa aacctaagag aggtaacgtt tacaggatat aaatttgccc
     3121 ggatagtcag tccgggcttt gtgtcgttat gtcacttggt cttgtgagtt tctttctttt
     3181 ctttcaaagt aaaatttaaa aatagaaggg ctaaaagaat tagcgcaatg ttcaccgacc
     3241 aagatttcca gcttgaagta ggatctaaaa tcgtattgaa gagcaagtga atgatagaag
     3301 aaaatgaaaa gagtaaaaat aatagtttgt tttgcgacat aaattgcttg acctttctgt
     3361 tgaaaattta gttgtaatta tagcataatt acataaaaca agaaataaat ccacaaaaaa
     3421 gaaattgcat aatagtttat tttgagtggt tcacttattc taagtacatt atttcagacc
     3481 ggtgagtaac ccataaacag attgcctctg ttggatttat atttattata ttattgtaaa
     3541 tgtagtattt ctagtagata atcaatgtac cttttagaat ccactataat tgatacatcg
     3601 gtctgcattc cattttttaa gtgtaaagtt gatccgttat cgttcataac tttatttttc
     3661 tctattgtgc tttcagcaat ataaaatttt tgtccgtttt gatcactaat actgtctgga
     3721 cttatttttg taatgacacc tttgatggtt tgatttgtat tttcaatatg gaatcttact
     3781 tcatcttttt cattaatatt tgtgatctca tgactcggaa tataaatatt agctttaagc
     3841 ttctctttat cagggataat agtcaaaata gcagtgcctg cttgtaaatt gtcacctgga
     3901 gatatatttg ttagtacatt aacatagccg tcacttgctg cttttatttt atatttttct
     3961 aattgtaaat ctatcatctt tagatcatcc tcttttgatt taagagtggt ctgaagatct
     4021 gtttgctttt gagatgtctg atttagcaag tttgttttga gctgttcaat agaaagctta
     4081 taatttgttt cctctgagtt atcggaatca ctgtcagaat cgtcactttt aattgaactg
     4141 ttaatctcat caagagattg atttaattcg tctttttctt cacttagttt tactaacata
     4201 tcttgtttta aactttcaag ctgtccgttc aagttctctt tctgctgtga aaaacggttt
     4261 ttatcaagct catctttcat cttccgtaga tcatcaagct gctgctctac attttgtttg
     4321 ttagtttgat aactattata gtaagaactg tacttatcat cctgtttggc aaaggattta
     4381 ttgtttttaa tggagtcttg cagatcagaa attctttgaa gctttagttt gactttgttt
     4441 tttgtcttat ccagactatc ttttatgctt tctttctgct tcttaagttt tttctgctga
     4501 gtttttgcat tttcttttga tgactctaac aaaatacttt gtttttcgta cgagagatat
     4561 tgatcttgat aaccccaatg atcgtcctca ctgaataaat ttttgtcatt ttcaatactt
     4621 ttttttagag ttttgtttaa cgcagcttgt tcttttaaat ctttgatatc tgctttaaca
     4681 gcttttttct gcgcttggat ttccgtattg tctagagtta atagagtatc tccctttttc
     4741 accttatcaa cctgtttaat gtcaactgtt tttactttgc cggctacttc gtttgttacg
     4801 ttgctgttag gctttgtata ttggatgtca gctgtcgttt ttagaatcac ttctttcttt
     4861 ccatagaaac taaaaacaat acatgcaata agtaaagcta tcagtatata tgtaaagaaa
     4921 acaccaattg gtttgggttt tgattcatag aattctctgc tatccttcaa atcatgtaaa
     4981 ttgaaaaagt tacgtttcat ctaaatagtc accatccctc tggatggcat ttggttctcc
     5041 cacaactcat agtacttgcc ttttttcttc aataaatcat tgtggttccc atactctatg
     5101 atttctccat tttccatgac aaatattttg tcacaattca taattgtact caaacggtga
     5161 gcgattataa tcgtagttat accaacagtc tgatcgtata tcatttttga tattccctgt
     5221 tcggtagtcg tatcgagatt gcttgttgat tcatccatta tgagaatgtt aggttttctt
     5281 aataatgctc tggcaattgc gagtctttgc ttctggcctc cagataaatt agacccgttt
     5341 tcctctacga gagtatcgta tctcattggt aaatcattga caaaatcgtg tacatttgtt
     5401 tgtttgcata cttctataat ctcttcaaag gtaaaactgc ctgagttacc gagcaaaagg
     5461 ttttcaagaa ttgatccttg tataaaatga gattcttgag ggatataact tatactttcc
     5521 cttaacgcgt tggtgtgaat atcatttata tgataaccat tgattaaaac ctcacctgat
     5581 tcagctgtat aaaatttcat taaaagctta gtcaaagtag attttcctga accgctttct
     5641 ccaacaaagg caactttctc tcctttttga atatgcagtg taatatcttt taagatgagc
     5701 cttcgagttc cgtatcgaaa attgatttta ttaaaagaaa gcggacctgt aattgacgac
     5761 gtcgatgtta tttgtgcctc tttctctttt aattcgggtt ctagctttag aatttctccg
     5821 agccttttgg acgcaacaga agctgattga agcttagatt gtaggccgat gatgttttgt
     5881 aaaggattta agaagtaggt taataaggca ttatatgtaa taagctgacc gatagtaagg
     5941 gtgcctttca tgacctgagt tgatccgatc cacagtatca atgcaccgct tgctaaatcc
     6001 aaaaacattt ttatggaact ctgaagatta tcaataactc cgtgtttaaa agctgatcgt
     6061 aagtatttca caaatctttt ttctgtttca aatgacatca tatattccgc attgtatgct
     6121 ttaacagttt cgatgccgtt aagcgtctca acaatctttg aagtcagctg cgcattgttt
     6181 tccatttctg tgttatttat attttcgtag ggttttataa atatccaaac cgtcaaaata
     6241 taaaaaggta tgaaagccaa tgtgatgaga aataaagtag tattctgcag atataagaaa
     6301 ataccaacca taataagcat aatggtatcg agtatgaccg aaagcgatgc actgacaact
     6361 gcatcgatca ctttattagc atcagtaaat ctggatataa tttctccgac ttttcgatta
     6421 ctgaaaaatt tcattggcaa agtaagcaca tgttgaaagt atccaaacat aatggagata
     6481 cttaattttt gtcctaggag aatcattagg tattgcctaa aacctattaa gaaaacctta
     6541 aataaataca taatcaaaag gccgattgaa agaatatgta atgtgttact taatccatta
     6601 ggcaggattt gatcgatgat cgtctgaaag taaaaagtac cgaggatccc gaagatggta
     6661 ataataaagg atgctaaaaa cgtatgtata atcaacgatt tttgctgaag aatcaacctg
     6721 aaaatatcgg cacttatatt acttgtttcg gtctgttttt tataagtctc agtaggtgct
     6781 aaaagtatta agatgcctgt ccaaatctta aaaaaatcat ctttttgata tgtaacgagc
     6841 ccttttccag gatccgcaat gataatctta tctttactaa ttttatgtat aacaacgtaa
     6901 tgcaataatt gctgatctat aataatatgt gcaattgctg gaagcgtaat ggactgatca
     6961 aaagctgtat gctctgcacg cacggctttt gctgaaaacc ccaattgttc ggcggctttt
     7021 accattccaa gagcactagt accttgtgta tcagttccag caatgtcacg tatataagct
     7081 agggagagct ttgaaccata atgttttgca attgttgata ggcaggctgc tccacaatct
     7141 ttttgatcaa gttgtcgtac acaatgatat ctattaaaaa acatatacta ctctccataa
     7201 tgaaggtcat tttttagaat agacatcatt ttattacatt ttcagggttt gtcaaccttt
     7261 ttcaggtaaa tatttattgc tatttagagc ttttggcacg tttatataat ataaatgcgt
     7321 agttgatata gataagatat aaagcaagat taaatacacc taagtgaaaa aaataagaaa
     7381 gagatataca aaataaaccc cctgcgatta tatagctata gaacaatttc attttaccaa
     7441 ctcctataaa tgttaaattc attgtaagat ataatggaca aaatgtaaaa tatatatgga
     7501 taaatgcaat atatagtttg catggttttt tcatgtatga tatgctacag ataaataaac
     7561 caatggagac ttgccaatga ataataattt gaagttggaa agaacaagag cgaatttaac
     7621 acaggaacaa cttgccgaaa aaattggagt gacaagacag acgattggat taattgaaaa
     7681 agggaagtat aatccttctt tacaattatg tttgaaaatt tgtatagaat tgaaagttac
     7741 tctgaatgat gtattttgga cgtataacag ggaggaagaa tctaatgaag gatgagagaa
     7801 taagtcatat tgaaaataag ataggtcatg aaagctttct tttagtaatt gctttggttt
     7861 ttgtctcttt tatactttcg attatgttta aaataccgag tacgttaatg acaattatca
     7921 tattgtttgt tggaagcgga tattatggat taagagctat gtcaaaaggt attttacgag
     7981 tcaatctgaa aaagaagaag aaaagttcgt actttctttt aattgttttt acttttattc
     8041 tgtatatggc aacgtcgata ttatttaaaa tcattacatt tccttttaca actaaagaat
     8101 ttttattcca aattcttatg tatatcttat ggctaattcc ttttagtctc atcatgtata
     8161 ctacatataa attttcaaac aggcagcaga aaaaagaatt agagaattaa ttaagagagc
     8221 ttaacctaaa taactgaatt aggttaagct ctcttttact atatataaat tgatgatagg
     8281 ttatatatat ttttatggaa aaaactattg atttaggatt tattatgtaa tatcataatc
     8341 cacgtggtaa atttatacta gtaattattt acctgaataa cttcgaggag gaatattgat
     8401 ggacacaaaa agcataaaag acgttgaact tcaggcattg actcttgaag aagctgaaca
     8461 aattgatgga ggcagttatg cgaaatatct tggcacttct gttgttacag gtgccggtgc
     8521 gggtgtagtt ggaggagttc caggtgttat tcttggtgcc catgcaggtg caattgcagg
     8581 atcagttggt tatttaggcg gatcattaat tgcaggaaaa tggctttaag gagggataac
     8641 acatcaatgg aaaataataa tcgtttttct gaattaaacg taaaagaaat ggaacaaatt
     8701 gatggcggag gctggagaag tgctcttggc ggagcttttt ccggagcatt agtcggtgct
     8761 tcaacagtag gcgtcggtgg agcagctgtt ggcggccctg ttggcggtgt cggcggagct
     8821 attactggcg gtatagttgg cggcattgtc ggcggaatca atgaatggtg aaaaatacat
     8881 aaacgactag tttagtacta tggtatacga ccggcaagag tcttctcttc ccggtcgtat
     8941 tatattttat aattgttaat taacgcataa aattgcgcag catgtttatt tcgtctcctc
     9001 cttccatttc tcatctaaca gcatcttccc aggccatgta tacgccatga tgccgccgtc
     9061 tgcggtgatg tcttctcctg tgacgtatga gctgtcgtct gaagcgagga acagcgccac
     9121 cgtcgccatt tctttcggct ggccgaggcg tccgagcggt gtgacccact tgtttgcttc
     9181 gcggaacttt tcgcccattt cctgttcttt ggtgcccgct agtttatcaa tcagcggggt
     9241 ttcgatcgta cccggcgaaa tggaattgac gcggattccg tcccgtgcgt agtcaatcgc
     9301 catcgctttt gtcaggtttg tgatgccgcc ttttgctgcg ttgtagccgg agcggtcaag
     9361 gtccgcggcc cggcctgaca tggaggaggt gttgatgatg gagcctcctt tttcgagcat
     9421 gagcggaatc agatatttgc tgcaaaggaa tgtgccgcgc aggtcgacgg cgataatgcg
     9481 gtcaaacagg tcaaccggat attcgtgcac ctttccgcct tcctgatcaa cgccggcgtt
     9541 attaaacaaa atatcaatcg ttccgcacgc ctccttgatt tgatcagcaa aagctttcac
     9601 gctgttttca tctgacacat cgaggtgaaa ggcgtccgcc tgtcctccat tttgtctgat
     9661 tgcttcaact gtttctttca tttggtcttc attgatgtcc ccgatcatca cacgcgcgcc
     9721 ttcattggca aaaacctctg ccgtcgcttg tccaatgcct gtcgcggcgc ctgtgatcac
     9781 tgcggttttg ttttcaagtc ttcccatgac acgacctcct ttttctattt gtcttcccgc
     9841 tctgtgcagt cataaacatg cgagaaagga aatgcatgtg ttaagatagg ctggaaattg
     9901 gttggggggt gtgtgagttg aaaatccagc ataagaagga gctcaagttt tattgcttcg
     9961 ttacaattcc atctgcattt attctgctga ctctcatctc gtttctattc aaagagatta
    10021 catttccagt tacagcaagc gcgtttctaa atgcttcatg gcataatcta ttatttttga
    10081 taccgttcgg tttgtttttc tatccggtgc atatttggat gaagcgggag tttggccgct
    10141 ggaatgacac agaaaaaaag agaggatgat gaagcctctc ttttttatga gaatgagtga
    10201 gaaaaagagt gaaaacaaat ccaactaatg ttaaatttac atatatatgc atctatcaat
    10261 ctaattgaca attgtcatct tatgtgataa atagatgctg aaaagggttt acataatggt
    10321 aaaggagcga tcaagagtgg caaaaaaaga gtttaaagca gagtctaaac gcttgctgga
    10381 tatgatgatt aactccattt atacccaaaa agaaattttc ctgcgcgagt taatctccaa
    10441 ttcgagtgat gcgattgaca aaatctatta caaagcgctt acggacgatg cgcttacgtt
    10501 tgataaagac agttactaca taaaggtcgc agctgacaaa gatgcgagaa cattaaccat
    10561 ctctgatacg gggatcggaa tgacaaagga tgagcttgaa cagcatcttg gaacaattgc
    10621 aaaaagcggt tccctcgcgt ttaaaaagga aaacgagctg aaagacggac atgacattat
    10681 cgggcagttc ggtgtcggtt tttacgcggc atttatggtt gccgatgtcg tgacagtcat
    10741 cagtaaagcg ctgggcagcg aagaggctta taaatgggag tctgcgggtg cagacggcta
    10801 tacgattgaa ccgtgtgaaa aggattctgt cggtacagac attatcctga aaatcaaaga
    10861 gaacacagaa gatgacagct atgacgagtt tttagaggaa tatcgtttaa aagcgatcat
    10921 caagaagtac tccgacttca ttcgctaccc gatcaaaatg gatacaacca ttaataagcc
    10981 gaaggaaggc agcgaaaatg aatttgaaga ggtgcaggaa gagcagacgg tcaacagcat
    11041 ggtgccgatc tggagaaaaa acaaaagcga gctgacagat gaggattatg aaaaattcta
    11101 tgctgaaaag cattacgggt ttgataaacc gctcacacac gttcatatca gtgtagatgg
    11161 agccgttcgc tacaacgcga ttctattcgt ccctgaaaac atgccgtttg actactattc
    11221 caaggaatat gagaaaggct tggagctgta ttccaatggc gtgctgatca tgaataagtg
    11281 cgcagacctg ctaccggacc acttcagctt tgtgaagggc atggtcgatt ctgaggatct
    11341 gtcgctgaac atttccagag aaatgctgca gcatgaccgc cagctgaagc tgatcgcgaa
    11401 aaacatcagc aagaaaatca aaagcgagct gcaaagcctg ttgaaaaaag accgcgagaa
    11461 atacgagacg ttctacaagt cgttcggcag acagctgaaa ttcggcgtgt acaatgattt
    11521 tggcgcgaat aaggatcaat tgaaggatct cctcttattc tactcttcaa aagagaaaaa
    11581 actggtcagc ttagacgagt atgtttccag aatgccagag gagcagaaat tcatttatta
    11641 cgcgaccggt gattcttacg accgcattga gaaactgccg caaacggaaa tggtggcgga
    11701 caaaggctat gaaatcctct actttactga ggacatcgat gagtttgcaa ttaaaatgct
    11761 ggcttcttat caggaaaaag aattcaagtc cgtatcaagc ggagaccttg gcatagacac
    11821 ggatgaggat caaaagcagt ccgaggaaga ggaaagcaag tacaaggatc tgtttgagga
    11881 aatgaaaaac attctgtcag acaaagtgaa aaacgtcaga atctcaaaac ggcttaaatc
    11941 acatccagtc tgccttgctg ctgacggcga agtgacaatt gagatggaaa aaatcttaaa
    12001 tgcgatgcct gacagccaaa atgtgaaggc ggaaaaagtg ctggaaatca acccaaatca
    12061 cgaggtattc caaacactgc aggacgcgtt tgaacaagat aaagagaagc tgagcctgta
    12121 cacaaacctt ctgtacaatc aggcgctcct catcgaaggc ctgccgattc aggaccctgt
    12181 ggaatttacg aacaatattt gcaaggtcat ggtgtaaaca gaaaaaggaa tcgtcccata
    12241 aggagacgat tccttttttt ataatgtacg ctcattcagc acttggtttt gggtgctttt
    12301 cttcttttta aaccgttttt tcaggcttgc ttcaatttcc tccaagcttt tccctttggt
    12361 ttccggcacc atgtagaacg cgaagaaaaa tgagagaaga caaatgactg agaaaaccat
    12421 aaagacccat gcgatgccca tcgcgcttag catcagcgga aagacaagcg acacgatcag
    12481 gttagccgcc gataacacca aagtcgtgaa ccctgtcgcg gctccgcgtg ctttggacgg
    12541 gaagagctca ggcatgagca cccacactac cggaccccat gtcgcctggt aaaagacgat
    12601 atagacaccg agaaagacta ctgtcatcca cgctgttgat gcggaaagtc cgagcgttag
    12661 gagcacgcct gataaagcag caaggctcag tgtgatgccg acacttcccc agatcagaag
    12721 ttttttgcgg ccgacacggt caattaagat catggcagtg atacacatga tgacgttgag
    12781 gatgccgatc cccattgtgc cgagcgccga agctgatgtg ccaagaccgg ccttcgtaaa
    12841 aatggttggc gcgtagtaga tgaccgtgtt aatgccgacc gcctgctgga aaatggcaag
    12901 gccgacgcca atcagaagca tggggcgaat ccatttggct tttaggacgc tgagtgtcgt
    12961 ttcttttttc tctgcttctc cttgcttcat ctctgccaat tccatttcga tgtcttttgg
    13021 atcatgagtg atgttcatga ttcgtctcgc ttcttcttca cggccgcgct tcacgagcca
    13081 tcttggcgat tctggcatga acgcgatgcc gattaataaa agcacggcag gcactgcggc
    13141 cagaccgacc atccagcgcc acgcttcaaa cggtgtgaac agatagttaa cgatataggc
    13201 gagcaaaatc ccggtgacaa tcattaagtt gttcattgtg ccgagtgtcc cgcgaatttt
    13261 cgtcggtgcc atttcggaaa gatacacggg cacaagcgcc gttgaaccgc cgacggccaa
    13321 cccgagcatc accctagatg caatcagcat gccgattgtt tgagaaaacg cgcaagcgag
    13381 cgctccgata atgaaaatga tggaaaggac aaatacaacc tttctcctgc cccagcggtc
    13441 ggagcatgtg ccgctcaagg cagaaccgaa aatcgcgcca aggagcagca tgctgacaac
    13501 caatccttct gtcaatgtcg ttaaaggaat atcgttattg ataaacagga gtgctccgga
    13561 gataacacct gtatcgtaac catatagcag tccccctaaa gcgccgaaaa agtagatcat
    13621 atatttcctt gtgtctttct tcacaaatgt ctcctcctca gttgttgagc caatgagtat
    13681 ctaaaatgta taacaaagtt aatagattag tacccatttc ctatctcatt tgaaacattt
    13741 gttttgaaaa aacggaaacg ttaaagccaa aagagatgat cacagatccg ctgagtttag
    13801 gaaaaacgaa ataactttat gctcagagaa accattaaaa aaaccttacc cgcgcggagt
    13861 aaggttttga t
//
