LOCUS       c00012_gnlPro..        13066 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IKHLGJIB_13.
ACCESSION   c00012_gnlPro..
VERSION     c00012_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 04:15:20
            Original ID  :: gnl|Prokka|IKHLGJIB_13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13066
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13066
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3066]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..3066
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13066
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13066
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             2..784
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_1"
                     /sec_met_domain="FAD_binding_2 (E-value: 5.2e-17, bitscore:
                     55.0, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.9e-43,
                     bitscore: 140.6, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GIIEIYEKFMGDDPRKLPMKIFPAVHYSMGGLWVDYDQMTNIPGL
                     FAAGECDYSMHGGNRLGANSLLSAIYGGMVAGPNAVKYVNGLESSAEDMSSSLFDAHVK
                     KEEEKWADIMSMDGTENAYVLHKELGEWMTANVTVVRHNDKLLKTDDKIQELMERFKKI
                     NINDTTKWSNQGAMFTRQFSNMLQLARVITLGAYNRNESRGAHYKPDYPERNDDEWLKT
                     TMAKHVSPYEAPEFEYQDVDVSLITPRKRDYSKKKVAK"
     CDS             787..1080
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 67.8; E-value: 2.5e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_2"
                     /sec_met_domain="Fer2_3 (E-value: 5.1e-21, bitscore: 67.8,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIRR
                     NPVNVKGEKTTPVTWDMNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRL"
     CDS             complement(1046..1303)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_3"
                     /sec_met_domain="Fer2_3 (E-value: 2.6e-16, bitscore: 52.7,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIRR
                     NPVNVKGEKTTPVTWDMNCLEEVCGACSMVINGLAVQAGQ"
     CDS             complement(1306..3066)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 294.2; E-value:
                     6.1e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_4"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.3e-89, bitscore:
                     294.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1e-42, bitscore:
                     138.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSSIIVVGGGLAGLMATIKAAESGMAVKLFSIVPVKRSHSVCA
                     QGGINGAVNTKGEGDSPWEHFDDTVYGGDFLANQPPVKAMCEAAPSIIHLLDRMGVMFN
                     RTPEGLLDFRRFGGTQHHRTAYAGATTGQQLLYALDEQVRRYEVAGLVTKYEGWEFLGA
                     VLDDDRICRGIVAQNLTNMQIESFRSDAVIMATGGPGIIFGKSTNSMINTGSAASIVYQ
                     QGAYYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRVWTYKDGKPWYFLEEKYPAYGN
                     LVPRDIATREIFDVCVNQKLGINGENMVYLDLSHKDPKELDIKLGGIIEIYEKFMGDDP
                     RKLPMKIFPAVHYSMGGLWVDYDQMTNIPGLFAAGECDYSMHGGNRLGANSLLSAIYGG
                     MVAGPNAVKYVNGLESSAEDMSSSLFDAHVKKEEEKWADIMSMDGTENAYVLHKELGEW
                     MTANVTVVRHNDKLLKTDDKIQELMERFKKININDTTKWSNQGAMFTRQFSNMLQLARV
                     ITLGAYNRNESRGAHYKPDYPERNDDEWLKTTMAKHVSPYEAPEFEYQDVDVSLITPRK
                     RDYSKKKVAK"
     CDS             complement(3100..3708)
                     /locus_tag="ctg12_5"
                     /transl_table=11
                     /translation="MSGNREFYFRRLHSLLGVIPVGIFLIQHLVVNQFAARGAEAFNSA
                     AHFMDSLPFRYALEIFIIFLPLIYHAVYGVYIAFTAKNNAGQYSYMRNWLFVLQRVTGI
                     ITLIFVSWHVWETRIAAQMGAEVNFDMMANILSSPAMLGFYIVGVLSTIFHFSNGLWSF
                     AVTWGITVTPRSQRISTYVTLIIFVALSYVGLKAIFAFV"
     CDS             4001..4447
                     /locus_tag="ctg12_6"
                     /transl_table=11
                     /translation="MKSKFEASIDNLKEIEMNAYAYELIREIVLPDMLGQDYSSMMYWA
                     GKHLARKFPLESWEEFPAFFEEAGWGTLTNVSAKKQELEFELEGPIISNRLKHQKEPCF
                     QLEAGFIAEQIQLMNDQIAESYEQVKKRADKVVLTVKWDMKDPV"
     CDS             complement(4491..5717)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_7"
                     /sec_met_domain="AA_kinase (E-value: 1.8e-55, bitscore:
                     181.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLIVQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMGK
                     STDELVSLAKAISDQPSKREMDMLLATGEQVTISLLSMALQEKGYDAVSYTGWQAGIRT
                     EAIHGNARITDIDTSVLADQLEKGKIVIVAGFQGMTEDCEITTLGRGGSDTTAVALAAA
                     LKADKCDIYTDVPGVFTTDPRYVKSARKLAGISYDEMLELANLGAGVLHPRAVEFAKNY
                     QVPLEVRSSTETEAGTLIEEESSMEQNLIVRGIAFEDQITRVTIYGLTSGLTTLSTIFT
                     TLAKRNINVDIIIQTQAEDKTGISFSVKTEDADQTVAVLEEYKDALEFEKIETESKLAK
                     VSIVGSGMVSNPGVAAEMFAVLAQKNILIKMVSTSEIKVSTVVSENDMVKAVESLHDAF
                     ELSKHPSAV"
     CDS             complement(6087..7859)
                     /locus_tag="ctg12_8"
                     /transl_table=11
                     /translation="MNKQLKEKLALLPDQPGCYLMKDRQQTVIYVGKAKVLKNRVRSYF
                     TGSHDAKTQRLVTEIEDFEYIVTSSNLEALILEMNLIKKHDPKYNVMLKDDKTYPFIKL
                     THERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCLYYH
                     LGQCLAPCVKDISEETNRELVESITRFLRGGYNEVKKELEEKMHEAAENLEFERAKELR
                     DQIAHIESTMEKQKMTMNDLVDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPLYQ
                     EADEEFLTFIGQFYSKNNHFLPKEILVPDSVDQSMIEQLLETNVHQPKKGPKKELLMLA
                     HKNAKIALKEKFSLIERDEERSIGAVQKLGEALNIYTPHRIEAFDNSNIQGTNPVSAMI
                     VFIDGKPYKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQ
                     INAARDVIENELGLDIPIAGLAKDEKHRTSNLLIGDPLEVVYLERNSQEFYLLQRIQDE
                     VHRFAISFHRQIRGKSAFQSVLDDIPGIGEKRKKMLLKHFGSVKKMKEASLEDIKKAGV
                     PTAAAQLLYDKLQK"
     CDS             complement(7995..8309)
                     /locus_tag="ctg12_9"
                     /transl_table=11
                     /translation="MAIVKATDQSFSAETSEGVVLADFWAPWCGPCKMIAPVLEELDQE
                     MGDKLKIVKIDVDENQETAGKYGVMSIPTLLVLKDGEVVETSVGFKPKEALQELVNKHL
                     "
     CDS             complement(8632..10140)
                     /locus_tag="ctg12_10"
                     /transl_table=11
                     /translation="MKGMIRGMSEHQAVIQTDIVKGTINKNLYGHFAEHLGRGIYEGIW
                     VGTDSDIPNINGIRKDVLEALKQLHIPVLRWPGGCFADEYHWANGVGDRKTMLNTHWGG
                     TIESNEFGTHEFMMLCELLECEPYICGNVGSGTVQEMAEWIEYMTFEEGTPMSDWRKQN
                     GREEPWNLKYFGVGNENWGCGGNMHPEYYADLYRRFQTYVRNYSGNDIYKIAGGANVDD
                     FNWTDVLMKKAAGLMDGLSLHYYTIPGDFWKGKGSATEFTEDEWFITMKKAKYIDELIQ
                     KHGTIMDRYDPEQRVGLIIDEWGTWFDPEPGTNPGFLYQQNTIRDALVAASHFHIFHQH
                     CRRVQMANIAQTVNVLQAMILTEGERMLLTPTYHVFNMFKVHQDASLLATETMSADYEW
                     NGETLPQISISASKQAEGDINITICNIDHQNKAEAEIELRGLHKAADHSGVILTAEKMN
                     AHNTFDDPHHVKPESFRQYTLSKNKLKVKLPPMSVVLLTLRADS"
     CDS             complement(10337..11314)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 150.7;
                     E-value: 1.3e-46)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg12_11"
                     /sec_met_domain="ETF (E-value: 2.7e-46, bitscore: 150.7,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 1.3e-37, bitscore:
                     120.8, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKKVIVLGEIRDGELRNVTFEAIAAGRTISGDGEVIGVLIGENV
                     QSIAQELIHYGADKVLTAEDPKLKTYTADGYSQVMRGVIEQENPDSVIFGHTAMGKDLS
                     PKLAARLQTGLISDAIDVSVTGGNVVFTRPIYSGKAFERVISTDPMIFATIRPNNIQAS
                     EKDISRSGSIESINVSLTDLRTVIQEVVKKTADGVDLSEAKIIVAGGRGVKSKEGFQPL
                     QALAEVLGAAVGASRGACDADYCDYALQIGQTGKVVTPDLYIACGISGAIQHLAGMSNS
                     KVIVAINKDPEADIFKIADYGIVGDLFEVVPLLTEEFKQLNIHS"
     CDS             complement(11350..12123)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 159.8;
                     E-value: 2.3e-49)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg12_12"
                     /sec_met_domain="ETF (E-value: 4.6e-49, bitscore: 159.8,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLFVLMKRTFDTEEKIVIETGKIQDDGAEWIINPYDEYAIEEAI
                     QLKEKHGGTITAVTVGGEEAEKELRTALAMGCDQAVLINIEDDLDEPDQYSISQVLYHY
                     MKDQEFDLILGGNVAIDGGSGQVAPRLAELLDIPCITTITKLEINGTDAEAERDVEGDV
                     EKIKTTLPLLVTAQQGLNEPRYPSLPGIMKAKKKPLEELELDDLDLDEEDAEPKLKTIE
                     RFLPPKKEAGKLLQGEPAEQAKELVSLLRSETKVI"
     CDS             complement(12138..12914)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ECH_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_13"
                     /sec_met_domain="ECH_1 (E-value: 3.3e-66, bitscore: 216.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAISLAVDQFVAVLTIHNPPANALSSRILEELSSCLDQCETDAG
                     VRSIIIHGEGRFFSAGADIKEFTSLKGNEDSSLLAERGQQLMERIESFPKPIIAAIHGA
                     ALGGGLELAMACHIRIAAEDAKLGLPELNLGIIPGFAGTQRLPRYVGTAKALELIGSGE
                     PISGKEALDLGLVSIGAKDEAEVIEKAKALAAKFAEKSPQTLASLLELLYSNKVYSYEG
                     SLKLEAKRFGEAFESEDAKEGIQAFLEKRKPQFKGE"
ORIGIN
        1 cggcatcatt gagatttatg agaaattcat gggagacgac ccgcgtaagc ttccaatgaa
       61 aatcttcccg gcggtccatt attctatggg cggtttatgg gtggattacg atcaaatgac
      121 aaatatccct ggactgtttg cggctgggga atgtgattat tctatgcacg gcggcaaccg
      181 cttgggagcg aactccctgc tgtctgcgat ttacggaggc atggtggccg gtccgaatgc
      241 ggtgaaatat gtaaacggct tagaatcttc agcggaagac atgtcttcat ctttattcga
      301 cgctcacgtt aagaaagaag aagaaaaatg ggctgatatt atgagtatgg acggaaccga
      361 aaatgcctat gttcttcaca aagagctcgg tgagtggatg acggcgaacg taacggttgt
      421 ccgccataat gacaagcttt tgaaaacgga tgacaaaatt caggagttaa tggagcgctt
      481 caaaaagatc aacatcaatg acacgacaaa atggagcaac cagggagcga tgttcacacg
      541 ccagttctcg aacatgcttc agcttgcgag ggtgattacc cttggcgcat acaaccgtaa
      601 tgaaagccgg ggcgcccatt ataaaccgga ttatcctgaa cgtaatgatg atgaatggct
      661 caaaacaaca atggctaaac atgtaagccc gtatgaagcg ccggaatttg agtatcagga
      721 tgtcgatgta tcactgataa cgcctcggaa acgggattac tcgaagaaga aggtggcgaa
      781 ataatcatga gtgaacaaaa aaccatacga tttattatca cacgtcaaga tacagctgac
      841 agcacgcctt atgatgaaga atttgagatt ccataccgcc cgaatctgaa cgtcatttcc
      901 gctctgatgg aaatccgccg gaatccggtt aatgtcaaag gtgagaagac aacccctgtc
      961 acatgggata tgaactgtct tgaggaagta tgcggcgcat gttcaatggt tataaacgga
     1021 aaaccccgcc agtcttgtac ggcgcttatt gaccagcttg aacagccaat ccgtttataa
     1081 ccattgaaca tgcgccgcat acttcctcaa gacagttcat atcccatgtg acaggggttg
     1141 tcttctcacc tttgacatta accggattcc ggcggatttc catcagagcg gaaatgacgt
     1201 tcagattcgg gcggtatgga atctcaaatt cttcatcata aggcgtgctg tcagctgtat
     1261 cttgacgtgt gataataaat cgtatggttt tttgttcact catgattatt tcgccacctt
     1321 cttcttcgag taatcccgtt tccgaggcgt tatcagtgat acatcgacat cctgatactc
     1381 aaattccggc gcttcatacg ggcttacatg tttagccatt gttgttttga gccattcatc
     1441 atcattacgt tcaggataat ccggtttata atgggcgccc cggctttcat tacggttgta
     1501 tgcgccaagg gtaatcaccc tcgcaagctg aagcatgttc gagaactggc gtgtgaacat
     1561 cgctccctgg ttgctccatt ttgtcgtgtc attgatgttg atctttttga agcgctccat
     1621 taactcctga attttgtcat ccgttttcaa aagcttgtca ttatggcgga caaccgttac
     1681 gttcgccgtc atccactcac cgagctcttt gtgaagaaca taggcatttt cggttccgtc
     1741 catactcata atatcagccc atttttcttc ttctttctta acgtgagcgt cgaataaaga
     1801 tgaagacatg tcttccgctg aagattctaa gccgtttaca tatttcaccg cattcggacc
     1861 ggccaccatg cctccgtaaa tcgcagacag cagggagttc gctcccaagc ggttgccgcc
     1921 gtgcatagaa taatcacatt ccccagccgc aaacagtcca gggatatttg tcatttgatc
     1981 gtaatccacc cataaaccgc ccatagaata atggaccgcc gggaagattt tcattggaag
     2041 cttacgcggg tcgtctccca tgaatttctc ataaatctca atgatgccgc caagcttaat
     2101 atcaagctct ttcggatctt tatgagacag atcgagatat accatgtttt caccgttaat
     2161 gccgagcttc tggttcacac acacatcaaa tatttcgcgt gtcgcaatat cacgcggcac
     2221 caggtttccg tatgccggat atttttcctc caggaaatac catggtttgc cgtctttata
     2281 tgtccacacg cgcccgcctt caccacgcgc tgattcactc atcagtctta gtttgtcatc
     2341 gcccggtatg gctgtcgggt ggatttgaat gaattctccg tttgcataat acgctccctg
     2401 ctgataaacg attgatgcag cagatcctgt attaatcatg gagttcgttg attttccaaa
     2461 gatgattccc ggtccgcccg tcgccataat gacagcgtct gaacggaagg attcaatttg
     2521 catgtttgtc aggttttgtg caacaattcc gcggcagatt ctgtcatcat ctaaaacagc
     2581 gccaaggaat tcccagcctt catattttgt gaccagaccc gcaacttcgt atctgcgcac
     2641 ttgctcgtcc agtgcgtaaa gcagctgctg tcccgtcgtc gcaccagcat aagcagttct
     2701 gtggtgctgt gtacccccga atcggcggaa atcaagcagg ccttcaggcg tccggttaaa
     2761 catgacgccc atccggtcta ataagtggat gatcgaaggc gccgcttcac acatcgcctt
     2821 gactggcggc tggttggcaa gaaagtctcc cccgtatacc gtgtcatcaa aatgttccca
     2881 cggagagtca ccttcccctt ttgtattgac cgctccgttt atgccgcctt gcgcacaaac
     2941 tgaatgagaa cgtttgacag gaacgatgga aaacaattta accgccattc ctgattccgc
     3001 tgctttaatt gtcgccatga ggccggcaag acccccgccg actacgataa tgcttgattg
     3061 actcatgata gcccctctcc ctctagtaat ctagtactct taaacaaatg cgaaaatcgc
     3121 ttttaagcct acgtatgaca gtgcaacaaa aataatcagc gtaacgtatg tcgaaattct
     3181 ttgagaacga ggcgttaccg tgatgcccca tgtaacagcg aaagaccata aaccgttcga
     3241 gaagtggaaa attgttgata aaacaccgac aatgtaaaaa ccaagcatag ccggagagct
     3301 caaaatattc gccatcatgt cgaaattgac ctcagcaccc atttgtgcgg caatgcgggt
     3361 ttcccacacg tgccagctga cgaaaatgag ggtgatgata ccggttacac gctgcaggac
     3421 gaatagccag tttctcatgt agctgtattg gccggcgtta tttttcgcag taaacgctat
     3481 gtacacacca taaactgcat gataaattaa tggtaagaag ataataaaaa tttccaaggc
     3541 atacctgaaa ggcaggctat ccataaaatg agcagcgcta ttgaatgctt cagcgcccct
     3601 tgcggcaaac tggttgacga ctaaatgctg aataagaaag atgccgaccg gtatgacgcc
     3661 aagcaaggaa tgcaatcttc gaaaataaaa ctctctgttc ccagacatta ctttaccccc
     3721 tgtttgataa gtgcgaaatg tgctaaatct cttcccccac ttctttcaat tgtaagcact
     3781 ttattaagat ttattgacaa tttcatttta ctcctccctc aaaagggcgt caagaaaacg
     3841 cgtacataaa ttataatttt ccgaattgat tagttgattg aaaaatttta ttttatcaat
     3901 atatatttct tgcttaattt ttcataagaa ttacaggatc attctgtaat cctcccccct
     3961 gtttgagcta taatatacgc aggagagagg ggagacagat atgaagtcta aatttgaagc
     4021 atctattgac aacctaaaag aaattgaaat gaacgcctat gcctacgaac taatacgaga
     4081 gatcgttctc ccagatatgc ttggccaaga ttactcttcc atgatgtatt gggcaggaaa
     4141 acatctcgcc cgtaagtttc ctcttgaatc atgggaggaa tttccggcct tctttgaaga
     4201 agcgggctgg ggaaccctca ccaacgtaag cgctaaaaaa caggagcttg aatttgaact
     4261 tgaagggccg atcatttcca accggcttaa acatcagaaa gaaccttgct ttcagctgga
     4321 agctggtttt atcgctgaac aaattcaatt gatgaatgat cagattgccg aatcatatga
     4381 acaagtgaaa aagagagccg ataaagtcgt tctgactgtg aaatgggata tgaaagaccc
     4441 agtgtaatca aaaaggcggt gactgcatag tcccgccttt ttgattgtca ttacacagct
     4501 gaagggtgtt ttgaaagctc aaatgcatcg tgaagcgact cgactgcttt caccatgtca
     4561 ttttcgctta cgactgttga cactttgatt tcagatgtgc tgaccatttt gattaaaatg
     4621 tttttttgcg ccagtacagc aaacatttca gccgctacac cgggatttga gaccatgccg
     4681 gatccaacaa tggatacttt agccaatttg ctttctgtct cgattttctc aaattccagc
     4741 gcgtctttat actcttcaag caccgcaacg gtttggtctg catcttctgt tttgacagag
     4801 aaggaaattc cagtcttgtc ctcggcctgc gtttggataa tgatatccac gtttatgttt
     4861 cttttggcaa gtgtcgtaaa aatagtagac aaagttgtca gaccgctagt cagcccgtaa
     4921 atggttactc ttgtgatttg atcttcaaat gcaatgcctc tgacaattaa attctgttcc
     4981 atggatgatt cctcctcaat taatgttccc gcttcggttt ctgtacttga acgcacttct
     5041 aacggcactt ggtaattttt cgcgaactca actgctctcg gatgaagaac gccggcgcct
     5101 aaattggcaa gctcaagcat ttcatcgtat gagatgcccg caagttttct cgctgatttc
     5161 acatagcgcg gatcagttgt aaacacgcct ggcacgtctg tgtatatgtc acatttatca
     5221 gcttttaaag cggcagccaa agcaactgct gttgtatctg aaccgccccg gcccaatgtc
     5281 gtaatttcac aatcctctgt catgccttgg aagcctgcaa caatgacaat ttttcctttt
     5341 tcaagctggt ctgctaaaac cgaagtgtcg atatctgtaa ttctggcgtt tccgtgaatg
     5401 gcctccgtac ggattcccgc ctgccagcca gtataagaca cagcgtcata gcctttttcc
     5461 tgcaatgcca ttgaaaggag tgaaatcgtg acctgctcgc ctgtcgccag cagcatatcc
     5521 atttcgcgtt tgctcggctg gtcagaaata gcttttgcaa ggctgaccaa ttcgtcagtg
     5581 gattttccca ttgctgaaac gacgacaacg acttgatggc ctttctgttt ttctgcaatt
     5641 gcgcggtttg ccgcattttg aattttttcg actgagccga cggaagtgcc tccgaatttt
     5701 tgtacaataa gacccatgta ttaccaccct ttacattttg gttcgtgcgg gtgaggagaa
     5761 agagcgcttt gtccacaata aaaaaagcaa tgagaggaat actctcattg cttatcaatt
     5821 aatcatcata aatgattatg aacaacgaga tagccctcca agaaaatgat ttcttgacag
     5881 ccttacattt attcaatgca cggccagcaa ataataccga tggggtttta cttgcttcgg
     5941 cgacgctccc ctttcagcct ttttcacaga atccatcttt ctccaaaggc atactcttga
     6001 agttcgcacc tctatcttca ccatataaca cgatctaact atgaaattag ttcacatttt
     6061 atcagatctt atttaaaagg acaacattat ttttgcaatt tgtcgtaaag gagctgagcc
     6121 gccgctgtgg gaacaccggc ttttttgatg tcctcaaggc ttgcttcctt cattttttta
     6181 acggaaccga aatgctttaa cagcattttc tttcttttct ctccgatacc cgggatgtcg
     6241 tccaaaacgg attgaaacgc gctttttccg cggatttgcc tgtgaaaact gattgcaaaa
     6301 cggtgcacct cgtcctgaat gcgctgcagg aggtaaaatt cctggctgtt tcgttccaga
     6361 tacaccacct ccagcggatc accgatcagt aaatttgagg ttctgtgttt ttcatctttc
     6421 gctaaaccgg cgatcgggat atccaagccg agttcatttt caataacatc ccttgctgcg
     6481 ttgatctgcc cttttcctcc gtcaatgata atcagatcgg gcagcggcag attctcacga
     6541 agcactctcg tatagcgtct tctgacaacc tctctcatag aaccgtaatc atccggccct
     6601 gtaacggttt tgattttata tttgcggtat tcctttttgt atggtttgcc atcgataaac
     6661 acaatcatcg cagaaaccgg gtttgtcccc tgtatgtttg agttatcaaa cgcttcaatt
     6721 ctgtgcggcg tataaatatt taatgcctca cctagtttct gcactgcccc gattgaacgc
     6781 tcctcgtccc gttcgattaa agagaatttt tctttcaatg cgattttcgc atttttatgg
     6841 gcaagcatga gcagttcttt tttcgggcct ttcttcggct ggtgaacgtt tgtttccagc
     6901 agctgctcga tcatggattg atctacgctg tccggaacta aaatctcttt cggaaggaag
     6961 tggttgtttt ttgaataaaa ctgcccgatg aacgtgagga actcttcatc tgcttcctga
     7021 taaagcggga acatgctgac atcgcgttca atgagcttcc cttggcggat gaaaaagacc
     7081 tgcacgcaca tccagccctt atcgtacgcg tacgcgaata catcacggtc gactagatcg
     7141 ttcatcgtca ttttttgttt ttccatcgtt gattcaatat gggcaatttg gtcacgaagc
     7201 tcttttgctc gttcaaactc aagattctca gcagcttcat gcattttctc ttcaagctct
     7261 tttttgacct cattatagcc gccccttaag aaacgtgtaa tgctttcaac cagctctctg
     7321 ttcgtctctt cggaaatatc ctttacgcac ggagcgaggc attggcccag atgatagtaa
     7381 aggcacactc tgtccgggag cttggagcat tttctgagag gatacagacg gtcgagcagt
     7441 ttttttgttt cccttgctgc ctgtacattc ggatacggcc cgaaatagcg ccctttgtct
     7501 tttttgacat tgcgggtgac aatcagcctt gggtggcgtt catgggtgag ttttatgaaa
     7561 ggataggttt tgtcgtcttt gagcatgacg ttgtatttcg gatcatgctt tttgatcaga
     7621 ttcatttcta aaataagcgc ttcaagattg gaggacgtca cgatatattc aaaatcctcg
     7681 atttccgtca caagcctttg ggttttcgcg tcgtgagaac cggtgaagta ggagcgcact
     7741 ctgtttttca gcacttttgc tttccctacg tagatcacag tctgctgccg gtccttcatg
     7801 agataacaac ccggttgatc aggaaggagg gcgagttttt ctttcagttg tttgttcata
     7861 tgttaccctt ccttatgttt aatcctttat ttccagttta acacgaacgt ttgtttttct
     7921 ctatggttca caattggcga ataaaaaaag cgatccctca atcggaatcg ctctggcatg
     7981 taagcagcgg aaaattaaag atgtttgttt acaagctctt gaagcgcttc ttttggtttg
     8041 aagccgactg aagtttcaac tacttcgccg tcttttaaca caagaagagt cgggatgctc
     8101 ataacgccgt attttccggc agtttcttgg ttttcgtcta catcgatttt tacgattttc
     8161 agtttgtctc ccatttcttg atccaattct tcaagaacag gtgcaatcat tttacaaggt
     8221 ccgcaccaag gagcccagaa gtctgccagt acgacgcctt cgcttgtttc agctgagaaa
     8281 gattgatcag ttgcttttac gatagccatt attgaattcc tccaatgtga aatgatgatt
     8341 tttagtatag catctcccat tcgttcacgc tattttaatg cttacaaatt attttttcct
     8401 gatcacagcc ggtttactca tttttatatg gttgaatggg atatgctctt tttttaaaac
     8461 acaaatctga taatggcccc gatcactaca attgccccaa taatcattaa aatggtacga
     8521 agcataagat cacatctcct cttcactgtc atgtacttta ccatgccctg ccggagctgt
     8581 tttaaaacct gaaaaagagc gccggcatga agctccggcg ctcttgcgcg attaagaatc
     8641 agcacgcagc gtaagtaaga cgactgacat tggcgggagt tttactttca gtttgttttt
     8701 gctgagcgtg tattgtctga aggattccgg tttgacatga tgaggatcgt caaacgtgtt
     8761 atgcgcattc attttttctg ccgtaagaat gactccggaa tggtccgctg ccttgtgtag
     8821 gcccctcagc tcgatttccg cctctgcttt gttttggtga tcgatgttgc aaattgtgat
     8881 attgatatcg ccttcagctt gtttcgacgc tgaaatgctg atttgcggaa gcgtttcacc
     8941 gttccattca tagtcggcag acattgtctc tgtggctaaa agagaagcgt cctgatgcac
     9001 cttaaacata ttgaatacat ggtacgtcgg tgtcaaaagc atccgctctc cctcagtcaa
     9061 aatcatcgct tgcagaacgt ttactgtttg ggcgatgttg gccatttgca cccggcggca
     9121 atgctgatgg aaaatgtgga aatgagaagc cgccaccagt gcatcacgaa tggtgttttg
     9181 ctgatataag aaaccgggat tcgtgcctgg ctcgggatca aaccacgtgc cccattcatc
     9241 aataatcagc ccgacccgct gctccggatc gtaccggtcc ataatcgtgc cgtgtttttg
     9301 aatcaattca tcgatgtatt tggctttttt catcgtaata aaccattcat cttccgtgaa
     9361 ttctgtggct gatcctttgc ccttccagaa atcccccgga atcgtgtaat aatgaagact
     9421 caacccgtcc atcaggccag cggctttttt cataagcacg tccgtccaat taaaatcatc
     9481 cacatttgcg ccgcctgcaa ttttataaat gtcattcccg ctgtaattgc ggacataagt
     9541 ctgaaaacgc cggtacagat ctgcgtagta ttcgggatgc atgttgccgc cgcagcccca
     9601 attttcatta cccacgccga aatatttcag attccaaggc tcttctcttc cattttgttt
     9661 tctccagtct gacatcggcg tgccttcttc aaatgtcata tactcaatcc actccgccat
     9721 ttcctgaacg gttccgcttc cgacattgcc gcaaatatat ggctcgcatt caagcagctc
     9781 gcaaagcatc ataaattcat gcgttccgaa ttcatttgat tcaattgtac cgccccagtg
     9841 agtgttcagc attgtcttac ggtcaccgac accgtttgcc caatgatatt cgtccgcaaa
     9901 acacccgccc ggccacctga ggacaggaat gtgcagctgt ttgagcgcct ccagcacgtc
     9961 ctttcgtatc ccgttgatat tggggatgtc tgagtccgtt ccaacccaga tcccctcata
    10021 aatccctctt cctaaatgct cagcaaaatg accgtataaa tttttgttaa tggttccttt
    10081 tacgatatct gtttgaatca ctgcttgatg ttcagacatg cctctgatca ttcctttcat
    10141 acggatatga aaagcaccac agtcaaatat gtgatctgtc ttttgcctga ggagtcagca
    10201 tgaatgtaag cgcttttaaa gtaaccatat tatatatgtt cgtacatgtc aacgacattt
    10261 tctattgttt ttatatttgt acgtatgtat ttataaatat gaaaaaatcc cgaactttta
    10321 aagtccggga tttcctttat gagtgtatat tcaattgttt gaattcctca gttaataacg
    10381 ggacaacttc aaataaatca ccgacgatgc cgtaatccgc tattttaaag atatcggctt
    10441 cggggtcttt attgatggcg acgatcacct tgctgtttga catgccggcc aaatgctgga
    10501 tggcgccgga aatgccgcat gcaatgtaca aatccggagt gacgactttc ccggtctgcc
    10561 cgatttggag agcataatcg caataatcag cgtcacatgc cccgcgagaa gccccgactg
    10621 cggcccctag cacctctgca agcgcctgca gcggctgaaa tccttccttg cttttgactc
    10681 ctcggccgcc cgcaacgata attttcgctt cggagagatc aacaccgtcc gccgtttttt
    10741 tcacgacctc ttgaatcacg gtgcgaaggt cagtaagaga gacatttatg ctttcgatgc
    10801 ttcccgatct gctgatgtct ttttctgaag cttgaatgtt attggggcga attgttgcaa
    10861 agatcatcgg atcggttgaa atgacgcgtt caaaagcttt ccccgagtaa atcgggcgtg
    10921 tgaacacaac attccctccg gtaacgctta catctatagc atcagaaatt aagcctgttt
    10981 gcagccgggc agcaagcttc ggtgaaagat ccttgcccat tgccgtatgc ccgaagatga
    11041 ctgaatcagg attttcttgc tcgataacac ctctcatgac ctggctgtac ccgtctgccg
    11101 tgtatgtttt cagcttcggg tcctcagcgg taagaacttt atctgctccg taatgaataa
    11161 gctcttgtgc aatgctttgt acattttcac cgatgagaac accgatgact tccccatctc
    11221 ctgaaatggt tcttcctgca gctattgctt caaaggtgac attccgcaat tccccatcgc
    11281 gtatttctcc aagcacgatc actttttttc ccattctaac atccccctgt ttctttgaat
    11341 gtccaagctt taaatgactt tagtttcgct gcggagcaat gaaacaagct cttttgcctg
    11401 ttcagcaggc tcaccttgga gaagcttccc ggcttctttt ttcggcggca gaaaacgttc
    11461 aatggttttc agctttggtt cggcatcctc ttcgtccagg tcaagatcat caagttcaag
    11521 ctcttcaagc ggctttttct tagccttcat aattcccgga agcgatggat agcgcggctc
    11581 gtttaagccc tgctgagctg tgacaagcaa tgggagcgtc gttttgattt tttcaacatc
    11641 cccttcgacg tctctttctg cttctgcatc agtgccgttg atttcgagtt tggtgatcgt
    11701 agtgatacac ggaatgtcca gtagctcggc aagccgaggc gccacttgtc ctgatcctcc
    11761 gtcaatggca acatttccgc cgagaatcaa atcaaactcc tgatccttca tatagtggta
    11821 taaaacttga gaaatggaat attggtcggg ttcatcaaga tcatcttcta tgttgattaa
    11881 aacagcttgg tcacaaccca tggcaagcgc cgtacgcaat tctttctccg cttcttcacc
    11941 gccgaccgtg acagcggtga tcgtgccgcc atgcttttcc ttcagctgga tggcttcttc
    12001 tatcgcgtac tcatcatatg gattaatgat ccattccgct ccgtcatcct gaatctttcc
    12061 tgtttcaatg acgatttttt cttctgtgtc aaacgtccgt ttcatcagta caaatagatt
    12121 catgatcata tcccctttta ttcgcctttg aactgaggct ttcttttttc gagaaatgcc
    12181 tggatgcctt ccttggcgtc ctctgactca aatgcttccc caaatcgctt tgcttcaagc
    12241 tttaagctgc cttcatagga atacaccttg ttggaataaa gaagttcaag caaagatgcc
    12301 agcgtttgcg ggcttttctc tgcaaactta gcggcaagtg cttttgcttt ttcaatcact
    12361 tctgcctcat ctttcgctcc aattgagaca agtccgagat caagcgcttc ttttccggat
    12421 attggttctc ctgatccgat gagctctaat gctttggctg tgccgacata tctcggaagg
    12481 cgctgtgtcc ccgcaaaacc tggaatgata ccgagattaa gctccgggag ccccagctta
    12541 gcatcttctg ccgcgattct gatgtgacag gccattgcaa gctccagccc gcctccgaga
    12601 gcagcgccgt gaatcgctgc gataatcggt tttggaaagc tttcgattct ctccattaac
    12661 tgctggccgc gctcagcgag caatgaggaa tcctcattgc ctttaagcga tgtaaattct
    12721 ttaatatcag cgccggctga gaaaaatctt ccctcgccgt gaatgataat gcttcgtacg
    12781 cctgcatctg tctcacattg atcaagacag gaagacagct cttctaatat ccggcttgaa
    12841 agcgcgtttg ccggcggatt gtgaatcgtc aagactgcca caaattgatc aaccgcaagt
    12901 gaaattgcat tcataggaca gaactccttt acttattgtg aattccggat accaataatt
    12961 ctaaaacgct gtttgaaagc gcaacgagat cgtacttttg gtcattcatc acccaagttg
    13021 tcacagtttc gtcaatcgtt ccaaaaatca tctgccgggc gaggcg
//
