LOCUS gnlProkkaGHFFDFOM_2 16786 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|GHFFDFOM_2. ACCESSION gnlProkkaGHFFDFOM_2 VERSION gnlProkkaGHFFDFOM_2 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2025-04-28 03:57:34 Original ID :: gnl|Prokka|GHFFDFOM_2 NOTE: This is a single region extracted from a larger record! Orig. start :: 0 Orig. end :: 16786 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..16786 /aStool="rule-based-clusters" /category="RiPP" /contig_edge="True" /core_location="[6189:6786]" /cutoff="20000" /detection_rule="(TIGR04223 or AgrB)" /neighbourhood="10000" /product="cyclic-lactone-autoinducer" /protocluster_number="1" /tool="antismash" proto_core 6190..6786 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="(TIGR04223 or AgrB)" /neighbourhood="10000" /product="cyclic-lactone-autoinducer" /protocluster_number="1" cand_cluster 1..16786 /candidate_cluster_number="1" /contig_edge="True" /detection_rules="(TIGR04223 or AgrB)" /kind="single" /product="cyclic-lactone-autoinducer" /protoclusters="1" /tool="antismash" region 1..16786 /candidate_cluster_numbers="1" /contig_edge="True" /product="cyclic-lactone-autoinducer" /region_number="1" /rules="(TIGR04223 or AgrB)" /tool="antismash" CDS complement(2..319) /locus_tag="ctg2_1" /transl_table=11 /translation="MSTTILSFQNRVVIETLHNEGRSLRYIANYLGFSKTTIFNELHRL NSEYQAGLAQTDFERKVSQRGRKSSLTKKLKHLIEGKIQVQKWSPEQVAHVVGIAYKTV YN" CDS complement(408..731) /locus_tag="ctg2_2" /transl_table=11 /translation="MSKLIAKNVFQLPKMNLLVLTTSAFLLALDVILYKIAIGPAYFQL SFGFLSMACIGYLYGPIWGGLLEMISDILSFTIFGSGAFQIAFLLTAFLGGFIDGLFLY GRL" CDS complement(926..1060) /locus_tag="ctg2_3" /transl_table=11 /translation="MIKSILKFCLAAILIVSGVLIGGTVLTAKGIDNLGDKLQDKLHG" CDS complement(1077..1322) /locus_tag="ctg2_4" /transl_table=11 /translation="MHWLWVLIIGAIIGAIAGAITNKGKSMGWISNIIAGLVGSAIGEA LLGSWGPQLAGMAIVPSIIGGVIVVAITSFVLTRMD" CDS 1668..3122 /locus_tag="ctg2_5" /transl_table=11 /translation="MTEKLTTETGQPWANNEHSQTAGARGPVLMQDYNLLEKLAHFDRE RIPERVVHAKGAGAKGFFELENDMGEYTKADLFNGVGKKTPVILRFSQVAGEKGYPDTV RDVRGFALKFYTQQGNYDLVGNNTPVFFVNDPLKFPDFIHSQKRDPKTNRRTQNMQWDF WAHSPESLHQVTYLMGDRGLPASYRTMNGYGSHTFKWVNQNGEQFWVKYHFISDQGVKN MTAQAAEKAMSQDLDYLQDDLYDAIQEKNYPSWTMYVQILPYEEGLNYKWDIFDVTKVI SHKDYPLIKVGKLTLNENPTNNFTDIEEAAMSPANFVPGIEPSPDKLLQGRLFSYKDAQ RYRLGANFEDLPVNKPVVPVHNYERDGYMKINNQGAEVNYEPNALHGPEEVPDAALSPD SVRGETRAQPYRYQVDYTTQAGDLYRLMSEPEQERLINTIKDALGQVTLPGVKELEIKQ FYEADKNYGTRVANALGMNIADIISD" CDS complement(3280..3717) /locus_tag="ctg2_6" /transl_table=11 /translation="MIRLYTQSSCHSSRVARQWLEAHGIEFKEKNFSVDSPTVQDLKRI LSLTEHGVDDIISARSKDYPEIAPKLPEMPLNEALKLLCDHPKLLRRPIIISDSKIQVG FNEDDIRQFIPRPVRRLKFNALLSRLDGNTGDHIINKRMVE" CDS complement(4073..4816) /locus_tag="ctg2_7" /transl_table=11 /translation="MISVYICEDDPKQLQQIRQIITKVIVDQQLDMSICLACQDPHELL DKVNAQQPQKAIYVLDIALNSDINGIQLASQIRDMGRRSKIIFITTHTELSLMVFQYQV EALDFILKDFPDSLYERFSKVLHVAQDRFQTDENDQDDYVQIKIGETVRSINVKSIIFF ESSTSPHKIVVHLDDGELEYYGLLKDVPDLSPNFYICHKSYVVNLKRIKSLDKHLRRLT MANGEKVLCSAQANRYLAKWLAKKS" CDS complement(4809..6071) /locus_tag="ctg2_8" /transl_table=11 /translation="MLMIVFQELSIYLIIKSLLRNIFFVRLFDVIFLSVCMLMSYIFLA KLGISFSFLMLMMFIFFTWWYVRVLSGALCITFQVFIWSIMVDHICDILTRLMKVPNGY VVVFVILSVVSLIFLNIVMDRTNFSPTFSNQSLNRITALLLMIIYLYIMLSEGLENQFQ VILSNLIILSVVMGLVLVIYNEYLKNVRAKYEVQKQRIQIQNDTRYMNEIEAHYNELRR FRHDYQNMLISIDEYLKTDDLEGLQEYYQKNLAPVSNRVLKEKYNLEDLSRVKVKSIKS ILFSKLSYAQSQEIEVHFDLKEPLIDITVNELDLDIALGIMLDNAIEASVGHADGEIMS AIFIEKNSTVFLIQNNVFEQLPPLWKLKEAGYSTKGKNRGIGLNSLSKIVNRNENMILE TRVLGAVFLQRLTVKRVSQND" CDS complement(6190..6786) /gene_functions="biosynthetic (rule-based-clusters) cyclic-lactone-autoinducer: AgrB" /gene_kind="biosynthetic" /locus_tag="ctg2_9" /sec_met_domain="AgrB (E-value: 1.2e-34, bitscore: 111.6, seeds: 181, tool: rule-based-clusters)" /transl_table=11 /translation="MEKPEQKLLLYKLSDRLFAAIQKNLQLERRQALLVKLGIDTVLNV IPKLIITIILALLLHELVPVLVFMGSFLVLRGFAYGRHLKSDLLCTILTIFVFVGVPYV IGTGISEVYRLLLSLIFVIIISIFAPADTVKNPITSKSLRKKLKRRAIGLSLILSLLQI VSNNYFGTIILIAMALAALLLMPYERRENYERKNV" CDS complement(7154..9268) /gene_functions="other (smcogs) SMCOG1223:ATPase (Score: 961.7; E-value: 5.4e-291)" /gene_kind="other" /locus_tag="ctg2_10" /transl_table=11 /translation="MANFYGNDPFFNNDMDDVFNQLFRRMDNQNSERARYLVNGQSLTP DEFAQYRATGKLPQNNKTIEVSKDGKQAVKKGGILEKLGTNLTEQARDGLLDPVIGREN EIQETAEILSRRTKNNPILVGDAGVGKTAVVEGLAQAIVAGKVPETIQDKEIYSIDLSS LEAGTQYRGSFEENIKQLVKEVKAAGNIILFFDEIHQIIGTGATGGEDGGKGLADIIKP ALSRGELTVIGATTQDEYRNTILKNAALARRFNDVVINEPTAADTLRILQGVKKLYEKH HHVVLPDDVLKAAVDYSIQYIPQRTLPDKAIDLIDMTAAHLAAKNSQTDVETLDQRVKK LEAAKEAAVKSEDFTKAADIKKSIEETKQKIKKTDQKEKITATIDDVAQSVERLTGIPV ADMGANDIEHLKNLDKRLKSKVIGQDEAVEMVAKAIRRNRAGFSEGDQPIGSFLFVGPT GVGKTELAKQLALDMFGNKNAIIRLDMSEYADRTAVSKLIGTSAGYVGYEDNANTLTER VRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVINFKNTIIIATSNAGFGN EALSGDKQRDQSLMDKLAPFFRPEFLNRFNGIVEFSHLTKQDLSQIVDLMLADVQKTLA KKSIKLEVTKAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDVKNLKADL VDAEIVISAA" CDS complement(9659..9892) /locus_tag="ctg2_11" /transl_table=11 /translation="MSVENNYCKLQQAHDQKCRVSLRFYKTNGQMVETVGYVTTIVPKA IAFMAITGHRHLIQLNRIITVSLQSQDRRYVM" CDS complement(10529..11629) /locus_tag="ctg2_12" /transl_table=11 /translation="MTVINGYEQSDREQKLTILNLPSLEAAAKKIIPSGGFGYISGGSE DEWTLKQNTMAFNHVQIVPRALTDMEQPSTQTQAFGIDLKTPIMMAPAAAQGLAHARGE AATAEGMAQVGALMAQSTYSSTSIADTAAAGKGAPQFFQLYMSKDWDFNQSLLDEAVKA GAKAIILTVDATVDGYREADIINNFQFPIPMANLTKFSEGDGKGKGIMEIYAAAAQKIS PADVRRITEYTNLPVIVKGIQSPEDALLAIGAGAQGIYVSNHGGRQLNGGPASFDVLHE IAQAVNGRVPIIFDSGVRRGSHVFKALANGADLVALARPIIYGLALGGAQGVASVVSHL NDELLIDMQLAGTKTIEDVKRAKLLR" CDS complement(11656..13404) /gene_functions="biosynthetic-additional (rule-based-clusters) TPP_enzyme_N" /gene_functions="biosynthetic-additional (rule-based-clusters) TPP_enzyme_C" /gene_functions="biosynthetic-additional (smcogs) SMCOG1055:pyruvate oxidase/decarboxylase (Score: 470.8; E-value: 1.1e-142)" /gene_kind="biosynthetic-additional" /locus_tag="ctg2_13" /sec_met_domain="TPP_enzyme_N (E-value: 8.1e-41, bitscore: 131.9, seeds: 75, tool: rule-based-clusters)" /sec_met_domain="TPP_enzyme_C (E-value: 8.4e-32, bitscore: 102.5, seeds: 323, tool: rule-based-clusters)" /transl_table=11 /translation="MTKIKAGQALAQVLVDWKIDHIYGITADSINNTVDGFYQEKDHLK YIQVRHEEVGALAAAADAKLTGTIGVSFGSAGPGAVHLLNGLYDAKMDHVPVLALVGQS ATSIMNTNFFQEMNQDPIFADVAEFHKQVTTAEQIPYVVDEAIRSAYATRSVSVVIIPD DLSGQDIEFDGFKTASLSGSQQVLMPKLDDVQQTIAALKAAQHPVLWIGKGAYNARQEV IAVSEKFSLPVLSTAPATGIMPTDHPNFMGSRGRLGTKPAFEVSQAADLVLFVGTNFPF ARYLPQGIKFIQVNNNLADLGKQHDADITVLADAKEFFQALLQSEVTIKPTKFLKAAQR DKQNWNRWLKTIATDDQGGLTAEGVLEAIKDNATDDAVFGLDVGNNTEWAIRQLPLNKQ QTFTMSAWYGTMGFGLPAGLAAQLNYPKKQVWSISGDGGYAMVMPDLLTEVKYHLPVIN VVLENKVLGFIQHEKLLANQAPYGIDLIGADWAKMADNMGAIGFKVTNLKELKATFQKV TQLQQNGNRLPIVIDAKIKNVDPIDTSFVPVDPENFDADTIAKYRERYGIAEADQPALS QLLNEL" CDS complement(13492..13917) /locus_tag="ctg2_14" /transl_table=11 /translation="MANTQLSDATHIMAYIALHTDDQLKSEHIASSLNTDPTMVRRMMS KLRKAGLLTSVRGVARPTLACSPNDITLKDIYVAVVAKRNFLNVDHNTSETCPVGSVIP RVMEKYYCDIQNSAEARMSRVTLQDIIDDISAVQQQA" CDS complement(14090..15901) /gene_functions="biosynthetic-additional (rule-based-clusters) TPP_enzyme_N" /gene_functions="biosynthetic-additional (rule-based-clusters) TPP_enzyme_C" /gene_functions="biosynthetic-additional (smcogs) SMCOG1055:pyruvate oxidase/decarboxylase (Score: 494.2; E-value: 8.6e-150)" /gene_kind="biosynthetic-additional" /locus_tag="ctg2_15" /sec_met_domain="TPP_enzyme_N (E-value: 3.5e-44, bitscore: 142.8, seeds: 75, tool: rule-based-clusters)" /sec_met_domain="TPP_enzyme_C (E-value: 3.9e-38, bitscore: 123.1, seeds: 323, tool: rule-based-clusters)" /transl_table=11 /translation="MVMKQTKQTNILAGAAVIKVLEAWGVDHLYGIPGGSINSIMDALS AERDRIHYIQVRHEEVGAMAAAADAKLTGKIGVCFGSAGPGGTHLMNGLYDAREDHVPV LALIGQFGTTGMNMDTFQEMNENPIYADVADYNVTAVNAATLPHVIDEAIRRAYAHQGV AVVQIPVDLPWQQIPAEDWYASANSYQTPLLPEPDVQAVTRLTQTLLAAERPLIYYGIG ARKAGKELEQLSKTLKIPLMSTYPAKGIVADRYPAYLGSANRVAQKPANEALAQADVVL FVGNNYPFAEVSKAFKNTRYFLQIDIDPAKLGKRHKTDIAVLADAQKTLAAILAQVSER ESTPWWQANLANVKNWRAYLASLEDKQEGPLQAYQVLRAVNKIAEPDAIYSIDVGDINL NANRHLKLTPSNRHITSNLFATMGVGIPGAIAAKLNYPERQVFNLAGDGGASMTMQDLA TQVQYHLPVINVVFTNCQYGFIKDEQEDTNQNDFIGVEFNDIDFSKIADGVHMQAFRVN KIEQLPDVFEQAKAIAQHEPVLIDAVITGDRPLPAEKLRLDSATSSAADIEAFKQRYEA QDLQPLSTYLKQFGLDDLQHQIGQGGF" CDS complement(16219..16629) /locus_tag="ctg2_16" /transl_table=11 /translation="MQGKRPDLDQRIQNAVFGLPLVRPDEQHRCLGTFYERIELRISFA EALKYNCSGVLQRLLKENSKYQLLINGQLDMDIMGQYIQSAKQNGVLFAIRNSQYYRAD SNSAAVILCADHALNRDTVDALERYPQLNKDV" ORIGIN 1 agttatagac cgtcttgtag gcaatcccca ccacatgggc aacttgttca ggggaccact 61 tctggacttg aatctttccc tcgatcaagt gtttaagttt tttagtgagc gaagacttcc 121 gcccccgttg actaaccttt cgttcaaagt cagtttgcgc tagcccagcc tggtactcac 181 tatttagccg gtgaagttcg ttaaagatgg tggtcttact aaagcctaag tagttagcga 241 tgtatcgcaa ggaacgtcct tcattatgaa gcgtttcaat gacaacacgg ttctggaatg 301 ataaaatagt ggtgctcatc aaggtccttc tttctaatgg attgtgtggt aacaccagta 361 aagaccttga tggttttttc tgtccactta aatgttcaac ttaaatttta caatctgcca 421 tataaaaaca aaccgtcaat aaatccccct aaaaatgcag ttaacaaaaa ggcaatctga 481 aacgcgccgg aaccaaaaat agtaaagctt aatatatcgg agatcatctc caagagacca 541 ccccaaatgg gaccatatag ataaccaata caagccatag acaaaaagcc aaaagataat 601 tgaaaatacg ctggtccgat agcaattttg tataaaataa cgtctaaggc caataagaaa 661 gccgatgtag tcagcactaa taaattcatt tttggcaact gaaaaacatt tttcgcaata 721 agtttagaca taggccaatc ctcttttttt gattttaatc ataccctcat tcttaataaa 781 agtaaatatt acttttattc gattgaaggt agtttaaaat tgtcgctctt gatttagttc 841 cttgaactca atgatattac tcatactaaa agccactaac aggtcaacta gtacacccat 901 cagtggctca ttgtaaaatt aatttttatc catgtaactt atcttgtaat ttatcaccca 961 agttatcaat tcccttagca gtaagtacgg tcccaccaat aagaacacca cttacgatta 1021 agattgcagc taaacaaaac tttaaaatgc ttttaatcat cgcaatcatc tccttactaa 1081 tccatccgtg tcagaacaaa tgaggttatc gcaacaacaa tcacaccacc aataattgaa 1141 ggaacaattg ccattccggc taattgtggt ccccatgatc ccaaaagagc ttccccaatt 1201 gcagatccaa ccaatccggc aataatatta ctaatccacc ccatcgattt acctttatta 1261 gtaatagcac ctgcaattgc accaataata gcaccaatga tcaaaaccca taaccaatgc 1321 ataaaatccc tcctagactt attaaaccgc ttaaatacaa taatagaatt acacgaatat 1381 ttaagccgat tcataaatga ttacttctta taattatcat tttacaatta tcgataatga 1441 tagacaaata taacacatta tttaataaat gggtcgctac tatttctcat gtgacgattc 1501 cgggtggcct agaaaatatc aaacagcttg atagctgatt aaaattaaac tacgccacat 1561 gaacgattaa cttaactgtg cataatgatt gaagtcactc tgttaaggtg ttagcgttta 1621 aattgtgcaa gagctttctt gtaatttacg tgaaaagggc gattaaaatg acggaaaaat 1681 taacgacgga aaccggccaa ccatgggcta acaatgaaca ttcccaaacg gcaggagctc 1741 gtggtcccgt attaatgcaa gactataatc ttttggaaaa actagcccat tttgatcgtg 1801 aacgaattcc agaacgggtc gttcatgcta agggggccgg agcaaaaggt ttttttgaac 1861 ttgaaaacga catgggggaa tatactaagg cagacttatt taatggtgtc ggtaagaaaa 1921 ctcccgtaat cttaaggttc tcacaagttg ccggtgaaaa aggttatcct gacactgttc 1981 gagacgtgcg cggttttgcc ttaaaatttt atactcagca aggcaattat gatctcgttg 2041 gaaacaacac accggtcttt tttgtaaacg accctttaaa atttcctgac ttcatccatt 2101 cacaaaaacg ggatcctaaa acgaaccgtc gtacgcaaaa tatgcaatgg gatttttggg 2161 ctcattctcc agaatcattg caccaggtca cttatttaat gggcgaccga ggacttcctg 2221 cgtcctatcg aaccatgaat ggttacggtt cccatacttt taaatgggtg aatcagaatg 2281 gcgaacagtt ttgggttaag tatcacttca tctcagacca aggcgttaaa aatatgactg 2341 ctcaagcagc tgaaaaagca atgagccaag atttagatta tttacaagat gacttatatg 2401 atgcaattca agaaaaaaat tacccatcat ggacgatgta tgtccaaatc ttgccatatg 2461 aggaaggtct aaactataaa tgggacattt ttgatgtcac taaagtcatc tcccacaaag 2521 actatccact aattaaagtc ggcaaactaa ctttaaatga gaatcccact aataacttta 2581 ccgatattga agaggcggcc atgtcgccag caaattttgt tcctggtatc gaaccatctc 2641 ccgacaaatt actacaaggt cgcctattct cctataaaga tgcacagcga tatcggttag 2701 gtgccaactt tgaagattta cccgtgaaca agccggttgt tccagttcat aattatgaac 2761 gtgatggtta catgaaaatt aataatcaag gtgctgaggt caactacgag cctaatgcac 2821 tgcatgggcc agaagaggtg ccggatgccg cactttcacc tgattctgtt cgtggtgaaa 2881 cacgcgcaca gccttatcgc tatcaagttg attacacaac tcaagcaggc gacctatatc 2941 gcttaatgtc agaacccgag caagaacgct taattaatac tatcaaagat gcgttaggcc 3001 aagttacttt gcctggtgtc aaagaactcg aaatcaagca attttatgag gccgacaaaa 3061 actacggtac acgcgtggct aatgctctgg gaatgaatat tgctgatatt atcagtgatt 3121 aatattttga ccggatgtta tccatcgcga tattattttt gttataaaga atgatgatgc 3181 cgtctcatgg ttattaacta aagagcgaca ggttagactc atatcgtgta agtctagccc 3241 gtcgctcttt aattaacaaa aaatcttaga tatagcttac tactcgacca tccttttatt 3301 aataatgtga tcccctgtat taccatctag acgactcaac aatgcattga actttagtcg 3361 ccgaactggt cgtggaataa attggcgaat atcatcttca ttaaagccaa cttgaatttt 3421 actatcacta atgatgatag gccgacgtaa caacttcgga tgatcacaca acaatttaag 3481 tgcctcattc aatggcattt cgggtaactt aggcgcaatt tcaggatagt ctttagatcg 3541 agctgagata atatcgtcta caccatgttc ggttaaactc aaaatacgtt ttagatcttg 3601 caccgtgggc gaatcaacac taaaattttt ctccttgaac tcaatcccat gtgcttccaa 3661 ccattgccgt gcaactctag aagaatgaca gcttgattgt gtatataacc taatcattcc 3721 taatctgccc ctctctcgtt aaaattcatc acagcgtatt gatcgacatt aacttctgcc 3781 tgtcacaaca tcctttaaac taaacgcatt cgttactgtc atgaccaatc caataccccg 3841 tgaacacatc tttattatag gctctgaaca agggacatac cgaccgtttt aagacgaata 3901 atctgaggat aatcgtttta agtacacttt taaacggttt aggaaagaac gaacccagta 3961 cacgtaatgc tgacaaatac cactgcaatt tctaatcgaa taacgctgaa ttttcatcac 4021 gtagcacata aaaagtcgcc tactaatttg gcaggcgact tccttggaac tattatgact 4081 ttttagcaag ccatttggct agataacgat tagcttgtgc agaacaaagc actttttcac 4141 catttgccat ggttaatcgt cgcaagtgct tgtccaatga cttaatgcgt ttcaagttaa 4201 caacatatga cttatgacat atatagaaat taggactcaa atcaggaacg tcctttaaca 4261 gtccatagta ttctaattca ccatcatcca aatggactac gattttatgg ggactggttg 4321 aactttcaaa aaatataatg cttttaacat taattgatct gaccgtctca ccaattttta 4381 tttgaacata gtcgtcttgg tcattttcat cggtttgaaa acgatcttgt gccacgtgta 4441 aaaccttgct aaatcgctca tacaaggaat ctggaaaatc cttaagaata aaatctaatg 4501 cctcaacttg atattgaaac accatcaaag ataactccgt gtgtgtcgtg ataaaaataa 4561 tcttgctgcg ccggcccatg tcacgaatct ggctagctag ttgaatacca ttaatatctg 4621 aattaagggc aatatctaac acatagattg ccttttgagg ctgctgtgca ttaaccttgt 4681 ctaacaattc gtggggatct tggcatgcta aacagatact catgtctagc tgttgatcga 4741 cgattacctt agtaatgatt tgccgtattt gttgtaattg tttcggatca tcttcgcaaa 4801 tgtagacact aatcattctg agatactcgc ttcaccgtca agcgttgtaa gaataccgct 4861 cctaagactc tggtttcgag tatcatgttc tcattgcgat taacaatctt acttaaacta 4921 ttcaatccaa tcccccgatt cttgccctta gtggaataac ctgcctcttt cagcttccat 4981 aagggtggta actgttcaaa aacattgttt tgaatcaaga acaccgtact atttttttcg 5041 ataaaaatgg cactcataat ctctccatca gcatgtccta ccgatgcttc aattgcatta 5101 tccaacataa ttcctaatgc aatgtctaaa tccaattcat taacagtaat gtcaattaat 5161 ggttccttta aatcaaaatg aacttcaatc tcttgcgatt gtgcatagct caacttacta 5221 aataggatac tcttaatcga cttcactttg acccgactca aatcttcaag attatatttt 5281 tcttttaaca cccgatttga aaccggtgca agattctttt gataatattc ttgtaaacct 5341 tctaaatcat cagttttcaa atattcatct atcgaaatca acatattctg atagtcatgt 5401 ctgaaacgtc gcaactcatt atagtgagct tcgatttcat tcatatagcg agtatcattt 5461 tgtatttgta ttctttgctt ttggacttca tatttggctc ttacattttt taaatattcg 5521 ttataaatca ccaatactaa ccccattaca actgacaata taattaaatt acttaatata 5581 acctggaact gattttccag accttcactc aacataatat acaagtatat tatcattaat 5641 aatagtgcgg ttatgcgatt taagctctga ttactaaacg tgggactgaa attcgtgcga 5701 tccattacaa tattaagaaa aattaagctt acgacactca atatgacaaa cactaccaca 5761 tacccattag gaactttcat taaacgagtt aatatatcac aaatatggtc aaccataatc 5821 gaccatatga acacttgaaa tgttatacat agtgcaccgc ttagaactcg tacataccac 5881 caagtgaaaa atataaacat cattaacatt aaaaaagaaa aactaattcc taactttgct 5941 aaaaaaatat aactcatcag catacagacg gataagaata taacatcaaa aagtctcaca 6001 aaaaatatat ttctcaacaa agatttaatt atcaaataga tagataattc ttggaagaca 6061 atcattaaca tatatctaca ctaatccttg ctttttaatt catcaggaat tttagtttcg 6121 aataatatcc catggcagca cataaccaac tgtttagtac ctacgtattg aaaaagatgg 6181 ctaagtactt tatacatttt ttctttcata attttccctc ctttcatagg gcattagtaa 6241 taaagcggct aatgccatcg caattaaaat gattgtgcca aaataattat tactaactat 6301 ttgtaacaaa ctcaaaatta atgacaatcc aattgcccgt cgctttaatt tttttctcaa 6361 tgacttcgat gtaataggat tctttaccgt atcagctgga gcaaaaatac ttatgattat 6421 tacaaatatt aaacttaata acaatctgta tacttcagaa ataccagttc caatcacata 6481 cggcacaccc acaaacacaa agatagttaa tatcgtacat aacaaatccg atttcaagtg 6541 acgtccatag gcaaagccac gcaaaactaa aaaactaccc ataaaaacta acactgggac 6601 caactcgtgt agcagcaacg ctaagataat agtaattatc agcttaggaa taacatttaa 6661 tacagtatca atgcctagtt taactagtaa tgcctgccgt ctttctagtt gaagattctt 6721 ttgaatcgca gcgaataacc ggtcgcttaa tttataaagc aatagttttt gttctggctt 6781 ttccatatcc cactcctata atgctcaaat acatacctgt atcaacagtt taaaacagta 6841 ttaattaatt gaaaagaata cataaataga ttaattattc aatattgttt taagactaga 6901 aataaacatt taaagataca tcagtttaat tattcatacg aaactaaagt ttcatataaa 6961 aagatcgtta atataaatca gtttcatcga tactccccct taatttttcc ttagattaca 7021 agtcaaacta gacttaattt cactaattca cattactcaa tagattaata tcaaatggtg 7081 aaaatcaacg aaaaaaggag atctatcaag caatctcctc ttacataaag ttatttatga 7141 acactgattt aagctaagct gccgatatca caatctcagc atccactaaa tcagccttca 7201 agtttttgac atctaagtgg tcaaggtaga aatccgttac cttgtcacga atttgttgtt 7261 caattactcg ccgtaatggc cgcgcaccca ttgcttcatc atagccttgt tccatcagcc 7321 aatctttggc cgctttagtt acctcaagtt tgatggattt tttggctaac gttttttgta 7381 catccgccaa catcaaatcg acaatttgac ttaagtcttg cttagtcaga tgtgaaaatt 7441 ccacgattcc attaaaacgg ttcagaaatt ctgggcggaa aaatggtgct aacttatcca 7501 ttaatgactg atctcgttgc ttgtcaccac ttaatgcttc attaccaaag ccagcattag 7561 aagtagcgat aataatcgta tttttgaaat taatgacatt gccttgtcca tccgttaagc 7621 gcccatcatc catcacttgt aacagtaacg ttaatacttg tggatcagcc ttttcaattt 7681 catctaataa tacaatggaa tatggattac gccgaacccg ttcagttaga gtattagcat 7741 tatcttcata gcctacgtat ccagccgagg taccaattaa tttcgacaca gctgtacgat 7801 cagcatattc actcatatct agccgaataa tcgcattttt atttccaaac atatctaagg 7861 ctaattgctt agctaattca gtctttccta cgccagttgg gcccacaaac agaaaacttc 7921 caattggctg atcaccctct gaaaagcccg cacggttacg ccgaattgcc ttcgctacca 7981 tttcaaccgc ttcatcttga ccgattacct tacttttcag acgcttatca agatttttca 8041 agtgctcaat atcattagcg cccatatcag caactggtat accagttaaa cgttcaaccg 8101 attgtgccac atcatcaatc gtggcagtga ttttttcttt ttgatccgtt tttttaattt 8161 tttgcttggt ttcctcgatc gacttcttga tatcagcggc ttttgtaaag tcctccgatt 8221 taacggcggc ctccttagct gcctctaatt ttttaacgcg ttgatccaat gtctcaacat 8281 cagtttgcga atttttagcc gctaaatgag ccgcagtcat gtcgatcaaa tcgatagctt 8341 tatctggcaa agtgcgttgt ggtatatatt ggattgaata atccacagcc gccttcaaaa 8401 catcatctgg taatacaaca tgatgatgct tttcgtacag ctttttaaca ccttgtaata 8461 tacgtaaagt gtcagcggcc gtcggttcat taatcacaac atcattgaat cgccgtgcca 8521 aagccgcatt tttcaaaata gtattgcgat attcatcttg agtcgtagcc ccgattacag 8581 tcagctcgcc acgtgacaaa gcaggtttaa tgatatcagc caatcctttg ccaccatctt 8641 caccaccagt ggcgcccgtg ccgataatct gatgaatttc atcgaagaat agaataatat 8701 taccagctgc tttaacttcc tttactagct gtttaatatt ttcttcaaaa gaaccgcgat 8761 attgagttcc tgcttccaaa gacgataaat caatcgaata gatttcttta tcttgaatcg 8821 tttctggaac tttaccagcc acaattgctt gtgccagacc ttcgacgact gcagttttac 8881 ctacaccagc atcaccaact aagattggat tatttttcgt cctacgactc aaaatttctg 8941 cagtttcttg aatctcattc tcacgtccaa tcactggatc tagtaatcca tcacgagcct 9001 gttccgtcaa attagtccct aacttttcta aaatcccccc ttttttaaca gcctgtttac 9061 catctttaga tacttctatt gttttattat tttggggtag cttaccagtt gctcggtatt 9121 gagcaaactc atccggtgtc agcgattgtc cattaactaa ataccgtgca cgctccgaat 9181 tttgattatc catgcgccga aataattgat tgaaaacatc atccatatca ttgttgaaaa 9241 aaggatcatt tccgtagaaa tttgccatat tacaacacct ccataaaaat ttatatgtgt 9301 aacttagtga ccataatatc ctttaaaact acaactgaat cgtatcacga tttttatgta 9361 tcgttaagta aagtgcttat agaatcaatt agaaataatt agaataattt tgtttaaaca 9421 aaagagaaat caatttcata aaatgaattg atttccctac aaggttccct atttaatagc 9481 ccttgataaa gaacttgaat taacaagtta ctttccagac caattttaat ttaagagact 9541 gcgactcaaa aagcacaccc agtatcaagt taaggccaac tagttatcgt taatattgcc 9601 acttaaatat caatactagc aatcatgata cacgcgtaaa atcataaacc aaaacatatt 9661 acatgacgta acggcggtct tgggactgta aactcacagt aatgattcta ttgagttgga 9721 taaggtgccg atgaccagta attgccataa atgcaattgc tttcggtaca atcgtagtga 9781 catagccaac tgtctcgacc atctgcccat ttgttttata aaaccgtaat gagactcgac 9841 atttttgatc atgcgcttgt tgtaatttac aataattatt ttcaacactc aaattaaagt 9901 ctcccgttca aagaattcag gtttatttat tcgtcagtga atctatgtgt ttgtttttct 9961 cattgttgac ggcgtaagtc cacattaagg agtcagctat tcagtaaaaa ctaaataact 10021 agtattcatg ttcagctcag tataatatgc attgatggtt actaatcaaa aatcgatctc 10081 taaatatcct aattactatg aaactttgaa gttaatttat gagaaaaata actcacaaca 10141 aaactcatga ttacaacctt gtcatcataa ctagattatg aaacattcag cctcctaaat 10201 aaaactggta tgcgcgcatg tgcgcatgtg tacagtatac tattgccaag tatgtctgaa 10261 taaccgtttt aagacttgaa aaactcagct gggtgcttta ggacgctttt tgtgcatttt 10321 aagacaatat cctaacttca acgccggcat agcttcaatt cgtcaatcag tgtcttagtt 10381 cctcagctat ttctgttcag aacatcttcc tattacaata aaaagcgttg atctcagcag 10441 aatttacttc caccaaaacc aacgctaaag tgttattata tcaggtattt taaattcatt 10501 tcagacatta tattcagcat tacttctact acctaagtaa tttagcacgt ttaacatctt 10561 caatcgtctt agttcccgct agttgcatat cgatcaacag ctcatcatta aggtgactca 10621 ctacggaagc gacaccctgc gcaccaccca atgctaatcc atagataatc ggccgagcaa 10681 gtgccaccag atctgcacca ttggctaacg ccttaaagac atgggagcca cgccgaacac 10741 cgctatcaaa aattattggg acgcgcccat taacggcttg cgcaatctcg tgtaaaacat 10801 caaaggaagc tggaccacca tttagttgcc gaccgccatg gtttgaaaca tagataccct 10861 gagcaccagc cccgattgct aacaaggcat cttctggtga ctgaatcccc ttcacaataa 10921 ctggtaaatt cgtatattcc gtaatacgcc gaacatcagc cgggctaatc ttttgcgccg 10981 cagcagcata gatttccatg atacctttcc ctttaccatc cccttcgctg aacttagtca 11041 agttagccat tgggattgga aactggaaat tgttgataat atcagcttca cgataaccgt 11101 caactgttgc atcaactgtc aaaatgattg ccttagcacc agccttcact gcttcatcca 11161 gtaaactctg attaaaatcc caatctttgc tcatatataa ttggaaaaat tggggcgcac 11221 ctttaccagc tgcggcagta tctgcaattg acgttgaaga gtaagtactc tgagccataa 11281 gtgccccaac ttgagccatc ccttcagcag tcgcagcttc accccgtgca tgtgccaatc 11341 cttgagcggc cgctggagcc atcataatag gcgttttgag atctatgcca aaagcctgag 11401 tctgtgtgct tggctgttcc atatccgtca atgctcgtgg cacaatttga acatggttaa 11461 aggccattgt attctgcttt aaagtccatt cgtcttctga cccaccacta atatagccaa 11521 agcctccgct cgggatgatc tttttagcag ctgcttccaa tgatggtaaa tttaaaatcg 11581 ttaacttttg ctcacgatca ctctgttcat atccattaat aactgtcatt atactaatct 11641 cctttacata accctttata attcatttaa taattggcta agtgccggtt gatccgcttc 11701 ggcgatacca tatcgttcac gatacttagc aatcgtatct gcatcaaagt tttccggatc 11761 tactggaaca aaactagtat caattggatc aacattttta atttttgcat caatcacaat 11821 tggtagccga ttaccattct gctgtagttg agtaactttc tggaacgttg ctttcaactc 11881 tttaaggtta gtcactttaa aaccaatcgc acccatgttg tctgccatct tggcccaatc 11941 agcaccaatc aagtcaatcc catacggcgc ctgattagcg agtaactttt catgttgaat 12001 aaagcctaat actttgtttt ctaaaaccac gttaatgact ggcaaatgat atttaacttc 12061 cgttagtaag tctggcatta ccatggcata accaccatca ccagaaatac tccaaacctg 12121 cttcttagga taattcaatt gggcggccaa acctgctggc aaaccaaaac ccatcgtgcc 12181 ataccaagcc gacatcgtaa aagtctgttg cttattcaat ggtaactgtc ggattgccca 12241 ttccgtatta ttcccaacat ccagaccaaa gacggcatca tcagtagcat tgtctttaat 12301 agcttctagc accccttcag ccgtcaaccc tccttgatca tcagtagcaa ttgtcttgag 12361 ccaccggttc cagttttgct tatcacgttg agcagctttc aagaacttag ttggcttaat 12421 tgtcacttcg gattgaagta atgcttggaa aaattctttt gcatctgcaa gaacagtaat 12481 atcagcatca tgttgtttgc ctaaatctgc taaattatta ttgacttgaa taaacttaat 12541 tccttgtggc aagtaacgtg caaatggaaa gttagtacca acaaacaaaa ctagatctgc 12601 cgcttgcgag acttcaaagg cgggtttagt tcctagtcga ccgcgagagc ccatgaaatt 12661 aggatgatca gttggcataa taccagttgc tggagccgtc gacaaaaccg gcaaactaaa 12721 tttttcagaa actgcgataa cttcttgacg cgcattatag gcacccttgc caatccataa 12781 aacagggtgt tgagcagctt tcaaagccgc tatcgtctgc tgaacgtcat ctaatttcgg 12841 cattaagacc tgttgactgc cgctaagtga agccgtttta aaaccatcaa actcaatatc 12901 ttgaccagac aaatcatctg gaataataac aacagaaacc gaacgggtcg cgtatgctga 12961 tctaattgct tcatcaacca cgtatggaat ctgttcagcc gttgtcactt gtttatgaaa 13021 ttcggctaca tctgcaaaaa ttggatcttg attcatttct tgaaagaagt tcgtattcat 13081 aatggatgtt gctgattgac cgactaaagc tagcaccggt acgtgatcca tcttggcatc 13141 gtataatccg ttcaagagat gaacggcgcc tggtcctgct gaaccaaagc taacaccaat 13201 cgtccccgtt aatttagcat ctgccgcggc agctaaagca ccaacttctt catgacgtac 13261 ttgaatatac ttcaagtggt ctttctcttg gtagaaccca tctaccgtat tattaatcga 13321 gtcagctgta ataccataga tatgatcaat tttccagtca accaacactt gtgccaatgc 13381 ttgtcctgct ttaattttag tcatttccat taccctcttt ttgttgttac ttttttaagc 13441 acaaccatat cctaaataaa aacttgatcc ttgtcaagtc tttatcttaa attatgcttg 13501 ttgttgaaca gcgctaatgt catcaataat atcttgcagc gtcactcgcg acatacgtgc 13561 ctcagcacta ttctgaatat cacaatagta tttttccatc actcgcggaa ttaccgaccc 13621 gaccggacac gtctccgaag tattatgatc aacgtttaaa aaattacgct tagccaccac 13681 tgctacatag atatctttca aggtaatatc attgggcgaa caagctaatg ttggtctagc 13741 aacgccacga accgaagtta acaagcctgc ttttcttaac ttactcatca ttcttctgac 13801 catggtagga tccgtattta aactactagc aatatgctca cttttcagct ggtcatcagt 13861 atgcaacgca atatatgcca taatatgcgt cgcatcactt aattgtgtat tagccatcta 13921 gacacctccc atatccatct ctattgttac ttattttagc acatctaaca tgaacataaa 13981 agcgattaag gaaataagtt aggcttcttt ccctaatcgc aacataagat tatttgataa 14041 tctccattaa ttcaatcaaa cttattcaag acaccgatag tagctgaatt taaaacccac 14101 cctgtccaat ttgatgttgc aaatcatcta agccaaattg ttttaaataa gttgaaagtg 14161 gttgtaaatc ttgagcttca taccgttgtt taaatgcttc aatatcagct gccgaactcg 14221 ttgccgaatc taaacgaagc ttttcagcag gcagtggccg atctcctgta atcaccgcat 14281 caatcagaac tggttcatgc tgagcgattg ctttggcttg ttcaaaaaca tcaggtaatt 14341 gctcaatctt attaactcga aaagcttgca tgtgcacgcc atcggcaatc ttactaaaat 14401 caatatcatt gaattcaacg ccaataaaat cattctgatt agtatcttcc tgctcatctt 14461 tgataaatcc atattggcag ttggtgaaaa caacattaat cactggtaaa tggtattgaa 14521 cttgcgtcgc caaatcttgc atggtcatcg aagcgccacc atcaccagcc agattaaaca 14581 cctgccgctc aggataatta agtttggcag caattgctcc cggaatacca actcccatcg 14641 tagcaaataa gttagaagta atgtgccgat tggatggcgt taatttcaaa tgtcgattcg 14701 cattcaaatt gatatcacca acatcaatcg aatagattgc atcaggctcc gcaattttat 14761 taaccgcacg tagcacttga tatgcttgta aaggcccttc ctgcttatct tctaatgaag 14821 ctagataagc ccgccaattt ttaacattgg ctaaattggc ttgccaccaa ggtgtcgact 14881 cccgttcaga tacctgtgct aaaattgcag ccagcgtctt ttgtgcatca gcaagtaccg 14941 caatatctgt tttatgtcgt ttacctaact tagctggatc aatatcaatt tgtaagaaat 15001 aacgcgtatt tttaaacgct ttggaaactt ctgcaaacgg ataattatta ccaacaaata 15061 aaacaacgtc agcttgcgca agtgcctcat tcgccggttt ttgtgccacc cgattagcag 15121 aacccaaata ggctggataa cgatctgcga caatcccctt agctggatac gtactcatta 15181 atggaatttt caacgtttta ctcaattgtt cgagttcttt accagcctta cgagctccaa 15241 tgccatagta aataagtggc cgttcagctg cgagtaaagt ctgtgtcaat ctcgtcactg 15301 cttgaacgtc gggttctggt aataacggcg tttgataact attagcggaa gcataccaat 15361 cttcagctgg aatctgttgc catggtaaat cgactggaat ttgcacaacc gcaacacctt 15421 ggtgcgcata ggcgcgtcga attgcttcgt caataacatg tggcaacgtg gcagcattga 15481 cggctgttac attataatct gcaacgtccg cataaatcgg attctcattc atttcttgga 15541 acgtatccat attcatccca gtagtgccaa attgaccaat aagcgctaga acagggacat 15601 ggtcttcacg cgcatcatat aacccattca taagatgagt gccaccaggt cccgctgagc 15661 cgaagcaaac cccgatttta cccgttagct tagcatcagc agcggcggcc attgcaccaa 15721 cttcttcatg ccgtacttga atataatgga ttcgatccct ttctgctgat aatgcgtcca 15781 taatcgaatt aattgaacct ccaggaatac catacaaatg atctactccc caagcttcta 15841 aaactttaat aactgctgca cctgctagta tgttagtttg ttttgtttgt ttcataacca 15901 taataaagcc cccatttcat gcacaattta attacgcaca atttaataaa cgaatattac 15961 catagcaaac gcttacattc aagtggtcat aaactcatgt tttttaccac ttaatcacga 16021 ttcaaacgca ttgtagatca acaacagcgc tagtctgctt gccttgatga accaccatcg 16081 ctgttgaaaa ttagtatctc atacattcgt tttttaaaca attttagtaa ttagtgtatg 16141 ttttacaggg gcatacttcc aacaatgtct gcatgtttag aagctagcca ttcttcgcct 16201 cacactacta ttttcgtttc atacgtcctt atttaattgt ggatagcgct ctagcgcatc 16261 tactgtatcc cgattcaaag catgatcagc acataaaata actgcagcac tattcgaatc 16321 tgcacggtaa tactgactgt ttctaattgc aaataacaca ccattttgtt ttgcagattg 16381 aatatattgc cccatgatat ccatatcaag ctgaccattt attaacaatt gatatttgct 16441 gttttctttc aaaaggcgct gtaagacgcc actacagtta tactttaacg cttcagcaaa 16501 cgaaattcgc aactcaatac gttcataaaa agtacctaaa caacgatgct gttcatcggg 16561 tctcactaag ggtaacccaa acactgcatt ctgaattcgt tgatctaaat ctggtcgttt 16621 accttgcata ctcacacctc attaagcaaa aatttctgtt ataaaagaca aaagaagatc 16681 caaacctcgc caagagattc agacccccat ttaaaaatcg attacgttgc atcgtatcta 16741 atccgtaatg ctttaaatta agaaagatat gtttatcgaa gaaacc //