LOCUS       gnlProkkaGHFFDFOM_2    16786 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GHFFDFOM_2.
ACCESSION   gnlProkkaGHFFDFOM_2
VERSION     gnlProkkaGHFFDFOM_2
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 03:57:34
            Original ID  :: gnl|Prokka|GHFFDFOM_2
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16786
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16786
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6189:6786]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6190..6786
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..16786
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16786
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(2..319)
                     /locus_tag="ctg2_1"
                     /transl_table=11
                     /translation="MSTTILSFQNRVVIETLHNEGRSLRYIANYLGFSKTTIFNELHRL
                     NSEYQAGLAQTDFERKVSQRGRKSSLTKKLKHLIEGKIQVQKWSPEQVAHVVGIAYKTV
                     YN"
     CDS             complement(408..731)
                     /locus_tag="ctg2_2"
                     /transl_table=11
                     /translation="MSKLIAKNVFQLPKMNLLVLTTSAFLLALDVILYKIAIGPAYFQL
                     SFGFLSMACIGYLYGPIWGGLLEMISDILSFTIFGSGAFQIAFLLTAFLGGFIDGLFLY
                     GRL"
     CDS             complement(926..1060)
                     /locus_tag="ctg2_3"
                     /transl_table=11
                     /translation="MIKSILKFCLAAILIVSGVLIGGTVLTAKGIDNLGDKLQDKLHG"
     CDS             complement(1077..1322)
                     /locus_tag="ctg2_4"
                     /transl_table=11
                     /translation="MHWLWVLIIGAIIGAIAGAITNKGKSMGWISNIIAGLVGSAIGEA
                     LLGSWGPQLAGMAIVPSIIGGVIVVAITSFVLTRMD"
     CDS             1668..3122
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="MTEKLTTETGQPWANNEHSQTAGARGPVLMQDYNLLEKLAHFDRE
                     RIPERVVHAKGAGAKGFFELENDMGEYTKADLFNGVGKKTPVILRFSQVAGEKGYPDTV
                     RDVRGFALKFYTQQGNYDLVGNNTPVFFVNDPLKFPDFIHSQKRDPKTNRRTQNMQWDF
                     WAHSPESLHQVTYLMGDRGLPASYRTMNGYGSHTFKWVNQNGEQFWVKYHFISDQGVKN
                     MTAQAAEKAMSQDLDYLQDDLYDAIQEKNYPSWTMYVQILPYEEGLNYKWDIFDVTKVI
                     SHKDYPLIKVGKLTLNENPTNNFTDIEEAAMSPANFVPGIEPSPDKLLQGRLFSYKDAQ
                     RYRLGANFEDLPVNKPVVPVHNYERDGYMKINNQGAEVNYEPNALHGPEEVPDAALSPD
                     SVRGETRAQPYRYQVDYTTQAGDLYRLMSEPEQERLINTIKDALGQVTLPGVKELEIKQ
                     FYEADKNYGTRVANALGMNIADIISD"
     CDS             complement(3280..3717)
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MIRLYTQSSCHSSRVARQWLEAHGIEFKEKNFSVDSPTVQDLKRI
                     LSLTEHGVDDIISARSKDYPEIAPKLPEMPLNEALKLLCDHPKLLRRPIIISDSKIQVG
                     FNEDDIRQFIPRPVRRLKFNALLSRLDGNTGDHIINKRMVE"
     CDS             complement(4073..4816)
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MISVYICEDDPKQLQQIRQIITKVIVDQQLDMSICLACQDPHELL
                     DKVNAQQPQKAIYVLDIALNSDINGIQLASQIRDMGRRSKIIFITTHTELSLMVFQYQV
                     EALDFILKDFPDSLYERFSKVLHVAQDRFQTDENDQDDYVQIKIGETVRSINVKSIIFF
                     ESSTSPHKIVVHLDDGELEYYGLLKDVPDLSPNFYICHKSYVVNLKRIKSLDKHLRRLT
                     MANGEKVLCSAQANRYLAKWLAKKS"
     CDS             complement(4809..6071)
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="MLMIVFQELSIYLIIKSLLRNIFFVRLFDVIFLSVCMLMSYIFLA
                     KLGISFSFLMLMMFIFFTWWYVRVLSGALCITFQVFIWSIMVDHICDILTRLMKVPNGY
                     VVVFVILSVVSLIFLNIVMDRTNFSPTFSNQSLNRITALLLMIIYLYIMLSEGLENQFQ
                     VILSNLIILSVVMGLVLVIYNEYLKNVRAKYEVQKQRIQIQNDTRYMNEIEAHYNELRR
                     FRHDYQNMLISIDEYLKTDDLEGLQEYYQKNLAPVSNRVLKEKYNLEDLSRVKVKSIKS
                     ILFSKLSYAQSQEIEVHFDLKEPLIDITVNELDLDIALGIMLDNAIEASVGHADGEIMS
                     AIFIEKNSTVFLIQNNVFEQLPPLWKLKEAGYSTKGKNRGIGLNSLSKIVNRNENMILE
                     TRVLGAVFLQRLTVKRVSQND"
     CDS             complement(6190..6786)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_9"
                     /sec_met_domain="AgrB (E-value: 1.2e-34, bitscore: 111.6,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKPEQKLLLYKLSDRLFAAIQKNLQLERRQALLVKLGIDTVLNV
                     IPKLIITIILALLLHELVPVLVFMGSFLVLRGFAYGRHLKSDLLCTILTIFVFVGVPYV
                     IGTGISEVYRLLLSLIFVIIISIFAPADTVKNPITSKSLRKKLKRRAIGLSLILSLLQI
                     VSNNYFGTIILIAMALAALLLMPYERRENYERKNV"
     CDS             complement(7154..9268)
                     /gene_functions="other (smcogs) SMCOG1223:ATPase (Score:
                     961.7; E-value: 5.4e-291)"
                     /gene_kind="other"
                     /locus_tag="ctg2_10"
                     /transl_table=11
                     /translation="MANFYGNDPFFNNDMDDVFNQLFRRMDNQNSERARYLVNGQSLTP
                     DEFAQYRATGKLPQNNKTIEVSKDGKQAVKKGGILEKLGTNLTEQARDGLLDPVIGREN
                     EIQETAEILSRRTKNNPILVGDAGVGKTAVVEGLAQAIVAGKVPETIQDKEIYSIDLSS
                     LEAGTQYRGSFEENIKQLVKEVKAAGNIILFFDEIHQIIGTGATGGEDGGKGLADIIKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNDVVINEPTAADTLRILQGVKKLYEKH
                     HHVVLPDDVLKAAVDYSIQYIPQRTLPDKAIDLIDMTAAHLAAKNSQTDVETLDQRVKK
                     LEAAKEAAVKSEDFTKAADIKKSIEETKQKIKKTDQKEKITATIDDVAQSVERLTGIPV
                     ADMGANDIEHLKNLDKRLKSKVIGQDEAVEMVAKAIRRNRAGFSEGDQPIGSFLFVGPT
                     GVGKTELAKQLALDMFGNKNAIIRLDMSEYADRTAVSKLIGTSAGYVGYEDNANTLTER
                     VRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVINFKNTIIIATSNAGFGN
                     EALSGDKQRDQSLMDKLAPFFRPEFLNRFNGIVEFSHLTKQDLSQIVDLMLADVQKTLA
                     KKSIKLEVTKAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDVKNLKADL
                     VDAEIVISAA"
     CDS             complement(9659..9892)
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MSVENNYCKLQQAHDQKCRVSLRFYKTNGQMVETVGYVTTIVPKA
                     IAFMAITGHRHLIQLNRIITVSLQSQDRRYVM"
     CDS             complement(10529..11629)
                     /locus_tag="ctg2_12"
                     /transl_table=11
                     /translation="MTVINGYEQSDREQKLTILNLPSLEAAAKKIIPSGGFGYISGGSE
                     DEWTLKQNTMAFNHVQIVPRALTDMEQPSTQTQAFGIDLKTPIMMAPAAAQGLAHARGE
                     AATAEGMAQVGALMAQSTYSSTSIADTAAAGKGAPQFFQLYMSKDWDFNQSLLDEAVKA
                     GAKAIILTVDATVDGYREADIINNFQFPIPMANLTKFSEGDGKGKGIMEIYAAAAQKIS
                     PADVRRITEYTNLPVIVKGIQSPEDALLAIGAGAQGIYVSNHGGRQLNGGPASFDVLHE
                     IAQAVNGRVPIIFDSGVRRGSHVFKALANGADLVALARPIIYGLALGGAQGVASVVSHL
                     NDELLIDMQLAGTKTIEDVKRAKLLR"
     CDS             complement(11656..13404)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 470.8;
                     E-value: 1.1e-142)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_13"
                     /sec_met_domain="TPP_enzyme_N (E-value: 8.1e-41, bitscore:
                     131.9, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.4e-32, bitscore:
                     102.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIKAGQALAQVLVDWKIDHIYGITADSINNTVDGFYQEKDHLK
                     YIQVRHEEVGALAAAADAKLTGTIGVSFGSAGPGAVHLLNGLYDAKMDHVPVLALVGQS
                     ATSIMNTNFFQEMNQDPIFADVAEFHKQVTTAEQIPYVVDEAIRSAYATRSVSVVIIPD
                     DLSGQDIEFDGFKTASLSGSQQVLMPKLDDVQQTIAALKAAQHPVLWIGKGAYNARQEV
                     IAVSEKFSLPVLSTAPATGIMPTDHPNFMGSRGRLGTKPAFEVSQAADLVLFVGTNFPF
                     ARYLPQGIKFIQVNNNLADLGKQHDADITVLADAKEFFQALLQSEVTIKPTKFLKAAQR
                     DKQNWNRWLKTIATDDQGGLTAEGVLEAIKDNATDDAVFGLDVGNNTEWAIRQLPLNKQ
                     QTFTMSAWYGTMGFGLPAGLAAQLNYPKKQVWSISGDGGYAMVMPDLLTEVKYHLPVIN
                     VVLENKVLGFIQHEKLLANQAPYGIDLIGADWAKMADNMGAIGFKVTNLKELKATFQKV
                     TQLQQNGNRLPIVIDAKIKNVDPIDTSFVPVDPENFDADTIAKYRERYGIAEADQPALS
                     QLLNEL"
     CDS             complement(13492..13917)
                     /locus_tag="ctg2_14"
                     /transl_table=11
                     /translation="MANTQLSDATHIMAYIALHTDDQLKSEHIASSLNTDPTMVRRMMS
                     KLRKAGLLTSVRGVARPTLACSPNDITLKDIYVAVVAKRNFLNVDHNTSETCPVGSVIP
                     RVMEKYYCDIQNSAEARMSRVTLQDIIDDISAVQQQA"
     CDS             complement(14090..15901)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 494.2;
                     E-value: 8.6e-150)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_15"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.5e-44, bitscore:
                     142.8, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.9e-38, bitscore:
                     123.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVMKQTKQTNILAGAAVIKVLEAWGVDHLYGIPGGSINSIMDALS
                     AERDRIHYIQVRHEEVGAMAAAADAKLTGKIGVCFGSAGPGGTHLMNGLYDAREDHVPV
                     LALIGQFGTTGMNMDTFQEMNENPIYADVADYNVTAVNAATLPHVIDEAIRRAYAHQGV
                     AVVQIPVDLPWQQIPAEDWYASANSYQTPLLPEPDVQAVTRLTQTLLAAERPLIYYGIG
                     ARKAGKELEQLSKTLKIPLMSTYPAKGIVADRYPAYLGSANRVAQKPANEALAQADVVL
                     FVGNNYPFAEVSKAFKNTRYFLQIDIDPAKLGKRHKTDIAVLADAQKTLAAILAQVSER
                     ESTPWWQANLANVKNWRAYLASLEDKQEGPLQAYQVLRAVNKIAEPDAIYSIDVGDINL
                     NANRHLKLTPSNRHITSNLFATMGVGIPGAIAAKLNYPERQVFNLAGDGGASMTMQDLA
                     TQVQYHLPVINVVFTNCQYGFIKDEQEDTNQNDFIGVEFNDIDFSKIADGVHMQAFRVN
                     KIEQLPDVFEQAKAIAQHEPVLIDAVITGDRPLPAEKLRLDSATSSAADIEAFKQRYEA
                     QDLQPLSTYLKQFGLDDLQHQIGQGGF"
     CDS             complement(16219..16629)
                     /locus_tag="ctg2_16"
                     /transl_table=11
                     /translation="MQGKRPDLDQRIQNAVFGLPLVRPDEQHRCLGTFYERIELRISFA
                     EALKYNCSGVLQRLLKENSKYQLLINGQLDMDIMGQYIQSAKQNGVLFAIRNSQYYRAD
                     SNSAAVILCADHALNRDTVDALERYPQLNKDV"
ORIGIN
        1 agttatagac cgtcttgtag gcaatcccca ccacatgggc aacttgttca ggggaccact
       61 tctggacttg aatctttccc tcgatcaagt gtttaagttt tttagtgagc gaagacttcc
      121 gcccccgttg actaaccttt cgttcaaagt cagtttgcgc tagcccagcc tggtactcac
      181 tatttagccg gtgaagttcg ttaaagatgg tggtcttact aaagcctaag tagttagcga
      241 tgtatcgcaa ggaacgtcct tcattatgaa gcgtttcaat gacaacacgg ttctggaatg
      301 ataaaatagt ggtgctcatc aaggtccttc tttctaatgg attgtgtggt aacaccagta
      361 aagaccttga tggttttttc tgtccactta aatgttcaac ttaaatttta caatctgcca
      421 tataaaaaca aaccgtcaat aaatccccct aaaaatgcag ttaacaaaaa ggcaatctga
      481 aacgcgccgg aaccaaaaat agtaaagctt aatatatcgg agatcatctc caagagacca
      541 ccccaaatgg gaccatatag ataaccaata caagccatag acaaaaagcc aaaagataat
      601 tgaaaatacg ctggtccgat agcaattttg tataaaataa cgtctaaggc caataagaaa
      661 gccgatgtag tcagcactaa taaattcatt tttggcaact gaaaaacatt tttcgcaata
      721 agtttagaca taggccaatc ctcttttttt gattttaatc ataccctcat tcttaataaa
      781 agtaaatatt acttttattc gattgaaggt agtttaaaat tgtcgctctt gatttagttc
      841 cttgaactca atgatattac tcatactaaa agccactaac aggtcaacta gtacacccat
      901 cagtggctca ttgtaaaatt aatttttatc catgtaactt atcttgtaat ttatcaccca
      961 agttatcaat tcccttagca gtaagtacgg tcccaccaat aagaacacca cttacgatta
     1021 agattgcagc taaacaaaac tttaaaatgc ttttaatcat cgcaatcatc tccttactaa
     1081 tccatccgtg tcagaacaaa tgaggttatc gcaacaacaa tcacaccacc aataattgaa
     1141 ggaacaattg ccattccggc taattgtggt ccccatgatc ccaaaagagc ttccccaatt
     1201 gcagatccaa ccaatccggc aataatatta ctaatccacc ccatcgattt acctttatta
     1261 gtaatagcac ctgcaattgc accaataata gcaccaatga tcaaaaccca taaccaatgc
     1321 ataaaatccc tcctagactt attaaaccgc ttaaatacaa taatagaatt acacgaatat
     1381 ttaagccgat tcataaatga ttacttctta taattatcat tttacaatta tcgataatga
     1441 tagacaaata taacacatta tttaataaat gggtcgctac tatttctcat gtgacgattc
     1501 cgggtggcct agaaaatatc aaacagcttg atagctgatt aaaattaaac tacgccacat
     1561 gaacgattaa cttaactgtg cataatgatt gaagtcactc tgttaaggtg ttagcgttta
     1621 aattgtgcaa gagctttctt gtaatttacg tgaaaagggc gattaaaatg acggaaaaat
     1681 taacgacgga aaccggccaa ccatgggcta acaatgaaca ttcccaaacg gcaggagctc
     1741 gtggtcccgt attaatgcaa gactataatc ttttggaaaa actagcccat tttgatcgtg
     1801 aacgaattcc agaacgggtc gttcatgcta agggggccgg agcaaaaggt ttttttgaac
     1861 ttgaaaacga catgggggaa tatactaagg cagacttatt taatggtgtc ggtaagaaaa
     1921 ctcccgtaat cttaaggttc tcacaagttg ccggtgaaaa aggttatcct gacactgttc
     1981 gagacgtgcg cggttttgcc ttaaaatttt atactcagca aggcaattat gatctcgttg
     2041 gaaacaacac accggtcttt tttgtaaacg accctttaaa atttcctgac ttcatccatt
     2101 cacaaaaacg ggatcctaaa acgaaccgtc gtacgcaaaa tatgcaatgg gatttttggg
     2161 ctcattctcc agaatcattg caccaggtca cttatttaat gggcgaccga ggacttcctg
     2221 cgtcctatcg aaccatgaat ggttacggtt cccatacttt taaatgggtg aatcagaatg
     2281 gcgaacagtt ttgggttaag tatcacttca tctcagacca aggcgttaaa aatatgactg
     2341 ctcaagcagc tgaaaaagca atgagccaag atttagatta tttacaagat gacttatatg
     2401 atgcaattca agaaaaaaat tacccatcat ggacgatgta tgtccaaatc ttgccatatg
     2461 aggaaggtct aaactataaa tgggacattt ttgatgtcac taaagtcatc tcccacaaag
     2521 actatccact aattaaagtc ggcaaactaa ctttaaatga gaatcccact aataacttta
     2581 ccgatattga agaggcggcc atgtcgccag caaattttgt tcctggtatc gaaccatctc
     2641 ccgacaaatt actacaaggt cgcctattct cctataaaga tgcacagcga tatcggttag
     2701 gtgccaactt tgaagattta cccgtgaaca agccggttgt tccagttcat aattatgaac
     2761 gtgatggtta catgaaaatt aataatcaag gtgctgaggt caactacgag cctaatgcac
     2821 tgcatgggcc agaagaggtg ccggatgccg cactttcacc tgattctgtt cgtggtgaaa
     2881 cacgcgcaca gccttatcgc tatcaagttg attacacaac tcaagcaggc gacctatatc
     2941 gcttaatgtc agaacccgag caagaacgct taattaatac tatcaaagat gcgttaggcc
     3001 aagttacttt gcctggtgtc aaagaactcg aaatcaagca attttatgag gccgacaaaa
     3061 actacggtac acgcgtggct aatgctctgg gaatgaatat tgctgatatt atcagtgatt
     3121 aatattttga ccggatgtta tccatcgcga tattattttt gttataaaga atgatgatgc
     3181 cgtctcatgg ttattaacta aagagcgaca ggttagactc atatcgtgta agtctagccc
     3241 gtcgctcttt aattaacaaa aaatcttaga tatagcttac tactcgacca tccttttatt
     3301 aataatgtga tcccctgtat taccatctag acgactcaac aatgcattga actttagtcg
     3361 ccgaactggt cgtggaataa attggcgaat atcatcttca ttaaagccaa cttgaatttt
     3421 actatcacta atgatgatag gccgacgtaa caacttcgga tgatcacaca acaatttaag
     3481 tgcctcattc aatggcattt cgggtaactt aggcgcaatt tcaggatagt ctttagatcg
     3541 agctgagata atatcgtcta caccatgttc ggttaaactc aaaatacgtt ttagatcttg
     3601 caccgtgggc gaatcaacac taaaattttt ctccttgaac tcaatcccat gtgcttccaa
     3661 ccattgccgt gcaactctag aagaatgaca gcttgattgt gtatataacc taatcattcc
     3721 taatctgccc ctctctcgtt aaaattcatc acagcgtatt gatcgacatt aacttctgcc
     3781 tgtcacaaca tcctttaaac taaacgcatt cgttactgtc atgaccaatc caataccccg
     3841 tgaacacatc tttattatag gctctgaaca agggacatac cgaccgtttt aagacgaata
     3901 atctgaggat aatcgtttta agtacacttt taaacggttt aggaaagaac gaacccagta
     3961 cacgtaatgc tgacaaatac cactgcaatt tctaatcgaa taacgctgaa ttttcatcac
     4021 gtagcacata aaaagtcgcc tactaatttg gcaggcgact tccttggaac tattatgact
     4081 ttttagcaag ccatttggct agataacgat tagcttgtgc agaacaaagc actttttcac
     4141 catttgccat ggttaatcgt cgcaagtgct tgtccaatga cttaatgcgt ttcaagttaa
     4201 caacatatga cttatgacat atatagaaat taggactcaa atcaggaacg tcctttaaca
     4261 gtccatagta ttctaattca ccatcatcca aatggactac gattttatgg ggactggttg
     4321 aactttcaaa aaatataatg cttttaacat taattgatct gaccgtctca ccaattttta
     4381 tttgaacata gtcgtcttgg tcattttcat cggtttgaaa acgatcttgt gccacgtgta
     4441 aaaccttgct aaatcgctca tacaaggaat ctggaaaatc cttaagaata aaatctaatg
     4501 cctcaacttg atattgaaac accatcaaag ataactccgt gtgtgtcgtg ataaaaataa
     4561 tcttgctgcg ccggcccatg tcacgaatct ggctagctag ttgaatacca ttaatatctg
     4621 aattaagggc aatatctaac acatagattg ccttttgagg ctgctgtgca ttaaccttgt
     4681 ctaacaattc gtggggatct tggcatgcta aacagatact catgtctagc tgttgatcga
     4741 cgattacctt agtaatgatt tgccgtattt gttgtaattg tttcggatca tcttcgcaaa
     4801 tgtagacact aatcattctg agatactcgc ttcaccgtca agcgttgtaa gaataccgct
     4861 cctaagactc tggtttcgag tatcatgttc tcattgcgat taacaatctt acttaaacta
     4921 ttcaatccaa tcccccgatt cttgccctta gtggaataac ctgcctcttt cagcttccat
     4981 aagggtggta actgttcaaa aacattgttt tgaatcaaga acaccgtact atttttttcg
     5041 ataaaaatgg cactcataat ctctccatca gcatgtccta ccgatgcttc aattgcatta
     5101 tccaacataa ttcctaatgc aatgtctaaa tccaattcat taacagtaat gtcaattaat
     5161 ggttccttta aatcaaaatg aacttcaatc tcttgcgatt gtgcatagct caacttacta
     5221 aataggatac tcttaatcga cttcactttg acccgactca aatcttcaag attatatttt
     5281 tcttttaaca cccgatttga aaccggtgca agattctttt gataatattc ttgtaaacct
     5341 tctaaatcat cagttttcaa atattcatct atcgaaatca acatattctg atagtcatgt
     5401 ctgaaacgtc gcaactcatt atagtgagct tcgatttcat tcatatagcg agtatcattt
     5461 tgtatttgta ttctttgctt ttggacttca tatttggctc ttacattttt taaatattcg
     5521 ttataaatca ccaatactaa ccccattaca actgacaata taattaaatt acttaatata
     5581 acctggaact gattttccag accttcactc aacataatat acaagtatat tatcattaat
     5641 aatagtgcgg ttatgcgatt taagctctga ttactaaacg tgggactgaa attcgtgcga
     5701 tccattacaa tattaagaaa aattaagctt acgacactca atatgacaaa cactaccaca
     5761 tacccattag gaactttcat taaacgagtt aatatatcac aaatatggtc aaccataatc
     5821 gaccatatga acacttgaaa tgttatacat agtgcaccgc ttagaactcg tacataccac
     5881 caagtgaaaa atataaacat cattaacatt aaaaaagaaa aactaattcc taactttgct
     5941 aaaaaaatat aactcatcag catacagacg gataagaata taacatcaaa aagtctcaca
     6001 aaaaatatat ttctcaacaa agatttaatt atcaaataga tagataattc ttggaagaca
     6061 atcattaaca tatatctaca ctaatccttg ctttttaatt catcaggaat tttagtttcg
     6121 aataatatcc catggcagca cataaccaac tgtttagtac ctacgtattg aaaaagatgg
     6181 ctaagtactt tatacatttt ttctttcata attttccctc ctttcatagg gcattagtaa
     6241 taaagcggct aatgccatcg caattaaaat gattgtgcca aaataattat tactaactat
     6301 ttgtaacaaa ctcaaaatta atgacaatcc aattgcccgt cgctttaatt tttttctcaa
     6361 tgacttcgat gtaataggat tctttaccgt atcagctgga gcaaaaatac ttatgattat
     6421 tacaaatatt aaacttaata acaatctgta tacttcagaa ataccagttc caatcacata
     6481 cggcacaccc acaaacacaa agatagttaa tatcgtacat aacaaatccg atttcaagtg
     6541 acgtccatag gcaaagccac gcaaaactaa aaaactaccc ataaaaacta acactgggac
     6601 caactcgtgt agcagcaacg ctaagataat agtaattatc agcttaggaa taacatttaa
     6661 tacagtatca atgcctagtt taactagtaa tgcctgccgt ctttctagtt gaagattctt
     6721 ttgaatcgca gcgaataacc ggtcgcttaa tttataaagc aatagttttt gttctggctt
     6781 ttccatatcc cactcctata atgctcaaat acatacctgt atcaacagtt taaaacagta
     6841 ttaattaatt gaaaagaata cataaataga ttaattattc aatattgttt taagactaga
     6901 aataaacatt taaagataca tcagtttaat tattcatacg aaactaaagt ttcatataaa
     6961 aagatcgtta atataaatca gtttcatcga tactccccct taatttttcc ttagattaca
     7021 agtcaaacta gacttaattt cactaattca cattactcaa tagattaata tcaaatggtg
     7081 aaaatcaacg aaaaaaggag atctatcaag caatctcctc ttacataaag ttatttatga
     7141 acactgattt aagctaagct gccgatatca caatctcagc atccactaaa tcagccttca
     7201 agtttttgac atctaagtgg tcaaggtaga aatccgttac cttgtcacga atttgttgtt
     7261 caattactcg ccgtaatggc cgcgcaccca ttgcttcatc atagccttgt tccatcagcc
     7321 aatctttggc cgctttagtt acctcaagtt tgatggattt tttggctaac gttttttgta
     7381 catccgccaa catcaaatcg acaatttgac ttaagtcttg cttagtcaga tgtgaaaatt
     7441 ccacgattcc attaaaacgg ttcagaaatt ctgggcggaa aaatggtgct aacttatcca
     7501 ttaatgactg atctcgttgc ttgtcaccac ttaatgcttc attaccaaag ccagcattag
     7561 aagtagcgat aataatcgta tttttgaaat taatgacatt gccttgtcca tccgttaagc
     7621 gcccatcatc catcacttgt aacagtaacg ttaatacttg tggatcagcc ttttcaattt
     7681 catctaataa tacaatggaa tatggattac gccgaacccg ttcagttaga gtattagcat
     7741 tatcttcata gcctacgtat ccagccgagg taccaattaa tttcgacaca gctgtacgat
     7801 cagcatattc actcatatct agccgaataa tcgcattttt atttccaaac atatctaagg
     7861 ctaattgctt agctaattca gtctttccta cgccagttgg gcccacaaac agaaaacttc
     7921 caattggctg atcaccctct gaaaagcccg cacggttacg ccgaattgcc ttcgctacca
     7981 tttcaaccgc ttcatcttga ccgattacct tacttttcag acgcttatca agatttttca
     8041 agtgctcaat atcattagcg cccatatcag caactggtat accagttaaa cgttcaaccg
     8101 attgtgccac atcatcaatc gtggcagtga ttttttcttt ttgatccgtt tttttaattt
     8161 tttgcttggt ttcctcgatc gacttcttga tatcagcggc ttttgtaaag tcctccgatt
     8221 taacggcggc ctccttagct gcctctaatt ttttaacgcg ttgatccaat gtctcaacat
     8281 cagtttgcga atttttagcc gctaaatgag ccgcagtcat gtcgatcaaa tcgatagctt
     8341 tatctggcaa agtgcgttgt ggtatatatt ggattgaata atccacagcc gccttcaaaa
     8401 catcatctgg taatacaaca tgatgatgct tttcgtacag ctttttaaca ccttgtaata
     8461 tacgtaaagt gtcagcggcc gtcggttcat taatcacaac atcattgaat cgccgtgcca
     8521 aagccgcatt tttcaaaata gtattgcgat attcatcttg agtcgtagcc ccgattacag
     8581 tcagctcgcc acgtgacaaa gcaggtttaa tgatatcagc caatcctttg ccaccatctt
     8641 caccaccagt ggcgcccgtg ccgataatct gatgaatttc atcgaagaat agaataatat
     8701 taccagctgc tttaacttcc tttactagct gtttaatatt ttcttcaaaa gaaccgcgat
     8761 attgagttcc tgcttccaaa gacgataaat caatcgaata gatttcttta tcttgaatcg
     8821 tttctggaac tttaccagcc acaattgctt gtgccagacc ttcgacgact gcagttttac
     8881 ctacaccagc atcaccaact aagattggat tatttttcgt cctacgactc aaaatttctg
     8941 cagtttcttg aatctcattc tcacgtccaa tcactggatc tagtaatcca tcacgagcct
     9001 gttccgtcaa attagtccct aacttttcta aaatcccccc ttttttaaca gcctgtttac
     9061 catctttaga tacttctatt gttttattat tttggggtag cttaccagtt gctcggtatt
     9121 gagcaaactc atccggtgtc agcgattgtc cattaactaa ataccgtgca cgctccgaat
     9181 tttgattatc catgcgccga aataattgat tgaaaacatc atccatatca ttgttgaaaa
     9241 aaggatcatt tccgtagaaa tttgccatat tacaacacct ccataaaaat ttatatgtgt
     9301 aacttagtga ccataatatc ctttaaaact acaactgaat cgtatcacga tttttatgta
     9361 tcgttaagta aagtgcttat agaatcaatt agaaataatt agaataattt tgtttaaaca
     9421 aaagagaaat caatttcata aaatgaattg atttccctac aaggttccct atttaatagc
     9481 ccttgataaa gaacttgaat taacaagtta ctttccagac caattttaat ttaagagact
     9541 gcgactcaaa aagcacaccc agtatcaagt taaggccaac tagttatcgt taatattgcc
     9601 acttaaatat caatactagc aatcatgata cacgcgtaaa atcataaacc aaaacatatt
     9661 acatgacgta acggcggtct tgggactgta aactcacagt aatgattcta ttgagttgga
     9721 taaggtgccg atgaccagta attgccataa atgcaattgc tttcggtaca atcgtagtga
     9781 catagccaac tgtctcgacc atctgcccat ttgttttata aaaccgtaat gagactcgac
     9841 atttttgatc atgcgcttgt tgtaatttac aataattatt ttcaacactc aaattaaagt
     9901 ctcccgttca aagaattcag gtttatttat tcgtcagtga atctatgtgt ttgtttttct
     9961 cattgttgac ggcgtaagtc cacattaagg agtcagctat tcagtaaaaa ctaaataact
    10021 agtattcatg ttcagctcag tataatatgc attgatggtt actaatcaaa aatcgatctc
    10081 taaatatcct aattactatg aaactttgaa gttaatttat gagaaaaata actcacaaca
    10141 aaactcatga ttacaacctt gtcatcataa ctagattatg aaacattcag cctcctaaat
    10201 aaaactggta tgcgcgcatg tgcgcatgtg tacagtatac tattgccaag tatgtctgaa
    10261 taaccgtttt aagacttgaa aaactcagct gggtgcttta ggacgctttt tgtgcatttt
    10321 aagacaatat cctaacttca acgccggcat agcttcaatt cgtcaatcag tgtcttagtt
    10381 cctcagctat ttctgttcag aacatcttcc tattacaata aaaagcgttg atctcagcag
    10441 aatttacttc caccaaaacc aacgctaaag tgttattata tcaggtattt taaattcatt
    10501 tcagacatta tattcagcat tacttctact acctaagtaa tttagcacgt ttaacatctt
    10561 caatcgtctt agttcccgct agttgcatat cgatcaacag ctcatcatta aggtgactca
    10621 ctacggaagc gacaccctgc gcaccaccca atgctaatcc atagataatc ggccgagcaa
    10681 gtgccaccag atctgcacca ttggctaacg ccttaaagac atgggagcca cgccgaacac
    10741 cgctatcaaa aattattggg acgcgcccat taacggcttg cgcaatctcg tgtaaaacat
    10801 caaaggaagc tggaccacca tttagttgcc gaccgccatg gtttgaaaca tagataccct
    10861 gagcaccagc cccgattgct aacaaggcat cttctggtga ctgaatcccc ttcacaataa
    10921 ctggtaaatt cgtatattcc gtaatacgcc gaacatcagc cgggctaatc ttttgcgccg
    10981 cagcagcata gatttccatg atacctttcc ctttaccatc cccttcgctg aacttagtca
    11041 agttagccat tgggattgga aactggaaat tgttgataat atcagcttca cgataaccgt
    11101 caactgttgc atcaactgtc aaaatgattg ccttagcacc agccttcact gcttcatcca
    11161 gtaaactctg attaaaatcc caatctttgc tcatatataa ttggaaaaat tggggcgcac
    11221 ctttaccagc tgcggcagta tctgcaattg acgttgaaga gtaagtactc tgagccataa
    11281 gtgccccaac ttgagccatc ccttcagcag tcgcagcttc accccgtgca tgtgccaatc
    11341 cttgagcggc cgctggagcc atcataatag gcgttttgag atctatgcca aaagcctgag
    11401 tctgtgtgct tggctgttcc atatccgtca atgctcgtgg cacaatttga acatggttaa
    11461 aggccattgt attctgcttt aaagtccatt cgtcttctga cccaccacta atatagccaa
    11521 agcctccgct cgggatgatc tttttagcag ctgcttccaa tgatggtaaa tttaaaatcg
    11581 ttaacttttg ctcacgatca ctctgttcat atccattaat aactgtcatt atactaatct
    11641 cctttacata accctttata attcatttaa taattggcta agtgccggtt gatccgcttc
    11701 ggcgatacca tatcgttcac gatacttagc aatcgtatct gcatcaaagt tttccggatc
    11761 tactggaaca aaactagtat caattggatc aacattttta atttttgcat caatcacaat
    11821 tggtagccga ttaccattct gctgtagttg agtaactttc tggaacgttg ctttcaactc
    11881 tttaaggtta gtcactttaa aaccaatcgc acccatgttg tctgccatct tggcccaatc
    11941 agcaccaatc aagtcaatcc catacggcgc ctgattagcg agtaactttt catgttgaat
    12001 aaagcctaat actttgtttt ctaaaaccac gttaatgact ggcaaatgat atttaacttc
    12061 cgttagtaag tctggcatta ccatggcata accaccatca ccagaaatac tccaaacctg
    12121 cttcttagga taattcaatt gggcggccaa acctgctggc aaaccaaaac ccatcgtgcc
    12181 ataccaagcc gacatcgtaa aagtctgttg cttattcaat ggtaactgtc ggattgccca
    12241 ttccgtatta ttcccaacat ccagaccaaa gacggcatca tcagtagcat tgtctttaat
    12301 agcttctagc accccttcag ccgtcaaccc tccttgatca tcagtagcaa ttgtcttgag
    12361 ccaccggttc cagttttgct tatcacgttg agcagctttc aagaacttag ttggcttaat
    12421 tgtcacttcg gattgaagta atgcttggaa aaattctttt gcatctgcaa gaacagtaat
    12481 atcagcatca tgttgtttgc ctaaatctgc taaattatta ttgacttgaa taaacttaat
    12541 tccttgtggc aagtaacgtg caaatggaaa gttagtacca acaaacaaaa ctagatctgc
    12601 cgcttgcgag acttcaaagg cgggtttagt tcctagtcga ccgcgagagc ccatgaaatt
    12661 aggatgatca gttggcataa taccagttgc tggagccgtc gacaaaaccg gcaaactaaa
    12721 tttttcagaa actgcgataa cttcttgacg cgcattatag gcacccttgc caatccataa
    12781 aacagggtgt tgagcagctt tcaaagccgc tatcgtctgc tgaacgtcat ctaatttcgg
    12841 cattaagacc tgttgactgc cgctaagtga agccgtttta aaaccatcaa actcaatatc
    12901 ttgaccagac aaatcatctg gaataataac aacagaaacc gaacgggtcg cgtatgctga
    12961 tctaattgct tcatcaacca cgtatggaat ctgttcagcc gttgtcactt gtttatgaaa
    13021 ttcggctaca tctgcaaaaa ttggatcttg attcatttct tgaaagaagt tcgtattcat
    13081 aatggatgtt gctgattgac cgactaaagc tagcaccggt acgtgatcca tcttggcatc
    13141 gtataatccg ttcaagagat gaacggcgcc tggtcctgct gaaccaaagc taacaccaat
    13201 cgtccccgtt aatttagcat ctgccgcggc agctaaagca ccaacttctt catgacgtac
    13261 ttgaatatac ttcaagtggt ctttctcttg gtagaaccca tctaccgtat tattaatcga
    13321 gtcagctgta ataccataga tatgatcaat tttccagtca accaacactt gtgccaatgc
    13381 ttgtcctgct ttaattttag tcatttccat taccctcttt ttgttgttac ttttttaagc
    13441 acaaccatat cctaaataaa aacttgatcc ttgtcaagtc tttatcttaa attatgcttg
    13501 ttgttgaaca gcgctaatgt catcaataat atcttgcagc gtcactcgcg acatacgtgc
    13561 ctcagcacta ttctgaatat cacaatagta tttttccatc actcgcggaa ttaccgaccc
    13621 gaccggacac gtctccgaag tattatgatc aacgtttaaa aaattacgct tagccaccac
    13681 tgctacatag atatctttca aggtaatatc attgggcgaa caagctaatg ttggtctagc
    13741 aacgccacga accgaagtta acaagcctgc ttttcttaac ttactcatca ttcttctgac
    13801 catggtagga tccgtattta aactactagc aatatgctca cttttcagct ggtcatcagt
    13861 atgcaacgca atatatgcca taatatgcgt cgcatcactt aattgtgtat tagccatcta
    13921 gacacctccc atatccatct ctattgttac ttattttagc acatctaaca tgaacataaa
    13981 agcgattaag gaaataagtt aggcttcttt ccctaatcgc aacataagat tatttgataa
    14041 tctccattaa ttcaatcaaa cttattcaag acaccgatag tagctgaatt taaaacccac
    14101 cctgtccaat ttgatgttgc aaatcatcta agccaaattg ttttaaataa gttgaaagtg
    14161 gttgtaaatc ttgagcttca taccgttgtt taaatgcttc aatatcagct gccgaactcg
    14221 ttgccgaatc taaacgaagc ttttcagcag gcagtggccg atctcctgta atcaccgcat
    14281 caatcagaac tggttcatgc tgagcgattg ctttggcttg ttcaaaaaca tcaggtaatt
    14341 gctcaatctt attaactcga aaagcttgca tgtgcacgcc atcggcaatc ttactaaaat
    14401 caatatcatt gaattcaacg ccaataaaat cattctgatt agtatcttcc tgctcatctt
    14461 tgataaatcc atattggcag ttggtgaaaa caacattaat cactggtaaa tggtattgaa
    14521 cttgcgtcgc caaatcttgc atggtcatcg aagcgccacc atcaccagcc agattaaaca
    14581 cctgccgctc aggataatta agtttggcag caattgctcc cggaatacca actcccatcg
    14641 tagcaaataa gttagaagta atgtgccgat tggatggcgt taatttcaaa tgtcgattcg
    14701 cattcaaatt gatatcacca acatcaatcg aatagattgc atcaggctcc gcaattttat
    14761 taaccgcacg tagcacttga tatgcttgta aaggcccttc ctgcttatct tctaatgaag
    14821 ctagataagc ccgccaattt ttaacattgg ctaaattggc ttgccaccaa ggtgtcgact
    14881 cccgttcaga tacctgtgct aaaattgcag ccagcgtctt ttgtgcatca gcaagtaccg
    14941 caatatctgt tttatgtcgt ttacctaact tagctggatc aatatcaatt tgtaagaaat
    15001 aacgcgtatt tttaaacgct ttggaaactt ctgcaaacgg ataattatta ccaacaaata
    15061 aaacaacgtc agcttgcgca agtgcctcat tcgccggttt ttgtgccacc cgattagcag
    15121 aacccaaata ggctggataa cgatctgcga caatcccctt agctggatac gtactcatta
    15181 atggaatttt caacgtttta ctcaattgtt cgagttcttt accagcctta cgagctccaa
    15241 tgccatagta aataagtggc cgttcagctg cgagtaaagt ctgtgtcaat ctcgtcactg
    15301 cttgaacgtc gggttctggt aataacggcg tttgataact attagcggaa gcataccaat
    15361 cttcagctgg aatctgttgc catggtaaat cgactggaat ttgcacaacc gcaacacctt
    15421 ggtgcgcata ggcgcgtcga attgcttcgt caataacatg tggcaacgtg gcagcattga
    15481 cggctgttac attataatct gcaacgtccg cataaatcgg attctcattc atttcttgga
    15541 acgtatccat attcatccca gtagtgccaa attgaccaat aagcgctaga acagggacat
    15601 ggtcttcacg cgcatcatat aacccattca taagatgagt gccaccaggt cccgctgagc
    15661 cgaagcaaac cccgatttta cccgttagct tagcatcagc agcggcggcc attgcaccaa
    15721 cttcttcatg ccgtacttga atataatgga ttcgatccct ttctgctgat aatgcgtcca
    15781 taatcgaatt aattgaacct ccaggaatac catacaaatg atctactccc caagcttcta
    15841 aaactttaat aactgctgca cctgctagta tgttagtttg ttttgtttgt ttcataacca
    15901 taataaagcc cccatttcat gcacaattta attacgcaca atttaataaa cgaatattac
    15961 catagcaaac gcttacattc aagtggtcat aaactcatgt tttttaccac ttaatcacga
    16021 ttcaaacgca ttgtagatca acaacagcgc tagtctgctt gccttgatga accaccatcg
    16081 ctgttgaaaa ttagtatctc atacattcgt tttttaaaca attttagtaa ttagtgtatg
    16141 ttttacaggg gcatacttcc aacaatgtct gcatgtttag aagctagcca ttcttcgcct
    16201 cacactacta ttttcgtttc atacgtcctt atttaattgt ggatagcgct ctagcgcatc
    16261 tactgtatcc cgattcaaag catgatcagc acataaaata actgcagcac tattcgaatc
    16321 tgcacggtaa tactgactgt ttctaattgc aaataacaca ccattttgtt ttgcagattg
    16381 aatatattgc cccatgatat ccatatcaag ctgaccattt attaacaatt gatatttgct
    16441 gttttctttc aaaaggcgct gtaagacgcc actacagtta tactttaacg cttcagcaaa
    16501 cgaaattcgc aactcaatac gttcataaaa agtacctaaa caacgatgct gttcatcggg
    16561 tctcactaag ggtaacccaa acactgcatt ctgaattcgt tgatctaaat ctggtcgttt
    16621 accttgcata ctcacacctc attaagcaaa aatttctgtt ataaaagaca aaagaagatc
    16681 caaacctcgc caagagattc agacccccat ttaaaaatcg attacgttgc atcgtatcta
    16741 atccgtaatg ctttaaatta agaaagatat gtttatcgaa gaaacc
//
