## Thu May 1 23:32:14 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_001639545.1/GCA_001639545.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_001639545.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_001639545.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs GHFFDFOM_00001 220668.lp_2143 2.73e-134 381.0 290YK@1|root,2ZNKB@2|Bacteria,1V5MF@1239|Firmicutes,4HX21@91061|Bacilli,3F5RH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Exosortase_EpsH GHFFDFOM_00002 220668.lp_2142 0.0 893.0 COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,3F53W@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family group 2 icaA - - - - - - - - - - - Chitin_synth_2,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 GHFFDFOM_00003 220668.lp_2141 0.0 1018.0 2DQSR@1|root,338EM@2|Bacteria,1VAQX@1239|Firmicutes,4HM5B@91061|Bacilli,3FBTQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - PMT_2 GHFFDFOM_00004 220668.lp_2137 2.51e-261 718.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,3F4IK@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE GHFFDFOM_00005 220668.lp_2136 0.0 2268.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,3F4U7@33958|Lactobacillaceae 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA GHFFDFOM_00006 220668.lp_2135 1.91e-66 201.0 COG4471@1|root,COG4471@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2129) ylbG - - - - - - - - - - - DUF2129 GHFFDFOM_00007 220668.lp_2134 6.06e-132 374.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,3F505@33958|Lactobacillaceae 91061|Bacilli L RNA methyltransferase, RsmD family rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 GHFFDFOM_00008 220668.lp_2133 2.99e-109 315.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,3F6YS@33958|Lactobacillaceae 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like GHFFDFOM_00009 220668.lp_2132 1.05e-251 690.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,3F4KY@33958|Lactobacillaceae 91061|Bacilli T Belongs to the peptidase S16 family lon - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 GHFFDFOM_00010 220668.lp_2131 1.27e-162 456.0 COG1555@1|root,COG1596@1|root,COG1555@2|Bacteria,COG1596@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,3F7NP@33958|Lactobacillaceae 91061|Bacilli L Competence protein ComEA comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB GHFFDFOM_00011 220668.lp_2130 7.1e-116 331.0 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HCDG@91061|Bacilli,3F6BF@33958|Lactobacillaceae 91061|Bacilli F ComE operon protein 2 comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 GHFFDFOM_00012 220668.lp_2129 0.0 1408.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,3F3VT@33958|Lactobacillaceae 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B GHFFDFOM_00013 220668.lp_2128 8.43e-240 660.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,3F3TP@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta GHFFDFOM_00014 220668.lp_2126 1.18e-46 150.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,3F7D8@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p GHFFDFOM_00015 1136177.KCA1_1802 2.9e-56 175.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,3F7DV@33958|Lactobacillaceae 91061|Bacilli J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 GHFFDFOM_00016 220668.lp_2124 3.84e-262 721.0 COG0477@1|root,COG2814@2|Bacteria,1U5GG@1239|Firmicutes,4IF7B@91061|Bacilli,3F5VM@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr GHFFDFOM_00017 220668.lp_2123 1.29e-200 556.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,3F4UH@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS GHFFDFOM_00018 220668.lp_2122 0.0 1126.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3U9@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL GHFFDFOM_00019 220668.lp_2121 4.84e-203 563.0 COG0457@1|root,COG0457@2|Bacteria,1VWCF@1239|Firmicutes,4HWSW@91061|Bacilli,3F6E0@33958|Lactobacillaceae 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - - GHFFDFOM_00020 220668.lp_2119 4.38e-286 781.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,3F3ZP@33958|Lactobacillaceae 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - ko:K02358,ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 GHFFDFOM_00021 220668.lp_2118 6.48e-288 790.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,3F40B@33958|Lactobacillaceae 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N GHFFDFOM_00022 220668.lp_2116 7.8e-300 818.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,3F41K@33958|Lactobacillaceae 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX GHFFDFOM_00023 220668.lp_2115 9.6e-143 402.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,3F44G@33958|Lactobacillaceae 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 GHFFDFOM_00024 220668.lp_2114 1.3e-65 200.0 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HM6C@91061|Bacilli,3F6WJ@33958|Lactobacillaceae 91061|Bacilli S mazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG GHFFDFOM_00025 220668.lp_2113 6.47e-95 276.0 2F916@1|root,341CT@2|Bacteria,1VY7K@1239|Firmicutes,4HX4B@91061|Bacilli,3F70S@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn GHFFDFOM_00026 220668.lp_2112 5.12e-31 108.0 2BSM8@1|root,32MPT@2|Bacteria,1U8BD@1239|Firmicutes,4II9D@91061|Bacilli,3FASU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00027 220668.lp_2111 0.0 931.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnPH2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1,SBP_bac_3 GHFFDFOM_00028 220668.lp_2110 3.97e-173 483.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran GHFFDFOM_00029 220668.lp_2109 0.0 1192.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,3F3MY@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N GHFFDFOM_00030 220668.lp_2108 2.62e-127 365.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,3F4M5@33958|Lactobacillaceae 91061|Bacilli M biosynthesis protein epsB - - - - - - - - - - - GNVR,Wzz GHFFDFOM_00031 220668.lp_2107 4.97e-157 441.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,3F4BM@33958|Lactobacillaceae 91061|Bacilli D Capsular exopolysaccharide family ywqD - - - - - - - - - - - AAA_31,ParA GHFFDFOM_00032 220668.lp_2106 5.54e-189 525.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli,3F3RT@33958|Lactobacillaceae 91061|Bacilli GM PHP domain protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - GHFFDFOM_00033 220668.lp_2105 1.44e-229 631.0 COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli,3F5GY@33958|Lactobacillaceae 91061|Bacilli M RmlD substrate binding domain cps4D - 5.1.3.2,5.1.3.25 ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 M00361,M00362,M00632 R00291,R02984,R10279 RC00289 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS00780 Epimerase,GDP_Man_Dehyd GHFFDFOM_00034 220668.lp_2104 3.31e-164 458.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HB15@91061|Bacilli,3F5PC@33958|Lactobacillaceae 91061|Bacilli M Bacterial sugar transferase tuaA - - - - - - - - - - - Bac_transf GHFFDFOM_00035 220668.lp_2103 1.4e-259 711.0 COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,1UHSF@1239|Firmicutes,4HB04@91061|Bacilli,3F428@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 cps4F - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 GHFFDFOM_00036 220668.lp_2102 1.94e-244 671.0 COG0438@1|root,COG0438@2|Bacteria,1V369@1239|Firmicutes,4HI0I@91061|Bacilli,3F64A@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase Family 4 cps4G - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 GHFFDFOM_00037 220668.lp_2101 8.1e-299 816.0 2AHJR@1|root,317XH@2|Bacteria,1U7PF@1239|Firmicutes,4IHKS@91061|Bacilli,3F9ZB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00038 220668.lp_2100 3.4e-228 629.0 COG1215@1|root,COG1215@2|Bacteria,1UZYU@1239|Firmicutes,4HQ2D@91061|Bacilli,3F6ND@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 cps4I - - - - - - - - - - - Glycos_transf_2 GHFFDFOM_00039 220668.lp_2099 0.0 902.0 COG2244@1|root,COG2244@2|Bacteria,1TRRI@1239|Firmicutes,4IEU9@91061|Bacilli,3F47P@33958|Lactobacillaceae 91061|Bacilli S MatE cps4J - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C GHFFDFOM_00040 220668.lp_2098 0.0 871.0 COG1409@1|root,COG1409@2|Bacteria,1UQCQ@1239|Firmicutes,4HE2R@91061|Bacilli,3FC19@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos GHFFDFOM_00041 220668.lp_2097 0.0 1075.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F44C@33958|Lactobacillaceae 91061|Bacilli GT Phosphotransferase System fruA - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB GHFFDFOM_00042 220668.lp_2096 4.24e-218 602.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli,3F3SG@33958|Lactobacillaceae 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB GHFFDFOM_00043 220668.lp_2095 3.02e-175 489.0 COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli,3F3JB@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain fruR - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR GHFFDFOM_00044 220668.lp_2094 8.98e-311 847.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,3F4ZA@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 GHFFDFOM_00045 220668.lp_2093 1.29e-59 184.0 2A5F6@1|root,30U54@2|Bacteria,1U6B4@1239|Firmicutes,4IG2N@91061|Bacilli,3F7HU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00046 220668.lp_2090 2.05e-228 628.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,3F4F1@33958|Lactobacillaceae 91061|Bacilli J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 GHFFDFOM_00047 220668.lp_2089 7.09e-180 501.0 COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HI3D@91061|Bacilli,3F41Y@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - ko:K07124 - - - - ko00000 - - - adh_short GHFFDFOM_00048 220668.lp_2088 1.84e-67 205.0 COG5416@1|root,COG5416@2|Bacteria,1VIG5@1239|Firmicutes,4HP5V@91061|Bacilli,3F7IW@33958|Lactobacillaceae 91061|Bacilli S Lipopolysaccharide assembly protein A domain - - - - - - - - - - - - LapA_dom GHFFDFOM_00049 220668.lp_2087 0.0 1481.0 COG0608@1|root,COG4199@1|root,COG0608@2|Bacteria,COG4199@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,3F42C@33958|Lactobacillaceae 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C GHFFDFOM_00050 220668.lp_2086 1.52e-120 344.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli,3F4DB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran GHFFDFOM_00051 220668.lp_2085 7.9e-136 384.0 COG0640@1|root,COG0640@2|Bacteria,1VZ80@1239|Firmicutes,4IFVN@91061|Bacilli,3F74V@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_20 GHFFDFOM_00052 220668.lp_2084 2.87e-270 742.0 COG0477@1|root,2ZBIK@2|Bacteria,1UG5D@1239|Firmicutes,4H9W5@91061|Bacilli,3FBS8@33958|Lactobacillaceae 91061|Bacilli EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 GHFFDFOM_00053 220668.lp_2083 2.84e-75 225.0 COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,4HKGZ@91061|Bacilli,3F6YC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0145 family ybjQ - - - - - - - - - - - YbjQ_1 GHFFDFOM_00054 220668.lp_2082 3.98e-156 439.0 COG0500@1|root,COG2226@2|Bacteria,1TSAZ@1239|Firmicutes,4HIIG@91061|Bacilli,3F4S0@33958|Lactobacillaceae 91061|Bacilli Q Methyltransferase - - - - - - - - - - - - Methyltransf_11 GHFFDFOM_00055 220668.lp_2081 5.03e-43 140.0 29PQN@1|root,30ANU@2|Bacteria,1U6X5@1239|Firmicutes,4IGRE@91061|Bacilli,3F8NG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00056 1122147.AUEH01000006_gene1796 1.55e-75 246.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HA65@91061|Bacilli,3F3NJ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family int3 - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase GHFFDFOM_00062 1127131.WEISSC39_00160 2.9e-24 96.3 COG1396@1|root,COG1396@2|Bacteria,1TVRP@1239|Firmicutes,4HYT4@91061|Bacilli,4AYYK@81850|Leuconostocaceae 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_26 GHFFDFOM_00065 673832.D2IYT0_9CAUD 9.7e-87 263.0 4QAPV@10239|Viruses,4QV7H@35237|dsDNA viruses no RNA stage,4QPC3@28883|Caudovirales,4QKMY@10699|Siphoviridae 10699|Siphoviridae S DNA binding - - - - - - - - - - - - - GHFFDFOM_00071 1400520.LFAB_15810 1.4e-25 95.1 2BS4G@1|root,32M5D@2|Bacteria,1U89W@1239|Firmicutes,4II7U@91061|Bacilli,3FAR4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00074 1136177.KCA1_1069 1.49e-163 457.0 2CV27@1|root,32SWP@2|Bacteria,1VBY4@1239|Firmicutes,4HQXW@91061|Bacilli,3F5Z8@33958|Lactobacillaceae 91061|Bacilli S Putative HNHc nuclease - - - - - - - - - - - - HNHc_6 GHFFDFOM_00075 1139219.I569_01402 5.37e-79 246.0 COG3935@1|root,COG3935@2|Bacteria,1TQT6@1239|Firmicutes,4HHS9@91061|Bacilli,4B2RT@81852|Enterococcaceae 91061|Bacilli L DnaD domain protein - - - - - - - - - - - - DnaB_2,Phg_2220_C,Rep_Org_C GHFFDFOM_00076 1400520.LFAB_09190 1.92e-167 470.0 COG1484@1|root,COG1484@2|Bacteria,1V36Z@1239|Firmicutes,4HXKM@91061|Bacilli,3F6VF@33958|Lactobacillaceae 91061|Bacilli L IstB-like ATP binding protein - - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 GHFFDFOM_00078 1400520.LFAB_09180 1.23e-63 194.0 2A444@1|root,30SP6@2|Bacteria,1U7MG@1239|Firmicutes,4IHIN@91061|Bacilli,3F9WP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00079 1400520.LFAB_09145 4.28e-80 240.0 2E42J@1|root,32YZ1@2|Bacteria,1VMGI@1239|Firmicutes,4HRUN@91061|Bacilli,3F8JP@33958|Lactobacillaceae 91061|Bacilli S Transcriptional regulator, RinA family - - - - - - - - - - - - DUF722 GHFFDFOM_00080 1423816.BACQ01000027_gene951 1.06e-112 332.0 29WKP@1|root,30A22@2|Bacteria,1U636@1239|Firmicutes,4IFSG@91061|Bacilli,3F6XH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00081 1136177.KCA1_1079 1.01e-17 79.7 COG1403@1|root,COG1403@2|Bacteria,1VFKN@1239|Firmicutes,4HR16@91061|Bacilli,3F87W@33958|Lactobacillaceae 91061|Bacilli V HNH nucleases - - - - - - - - - - - - HNH GHFFDFOM_00082 1400520.LFAB_09130 2.72e-113 325.0 COG1403@1|root,COG1403@2|Bacteria,1VQIP@1239|Firmicutes,4HM74@91061|Bacilli,3F6KP@33958|Lactobacillaceae 91061|Bacilli L HNH nucleases - - - - - - - - - - - - AAA_33,HNH GHFFDFOM_00085 947981.E9LUP8_9CAUD 1.4e-104 302.0 4QBS6@10239|Viruses,4QUNW@35237|dsDNA viruses no RNA stage,4QPP2@28883|Caudovirales,4QM0S@10699|Siphoviridae 10699|Siphoviridae S Phage terminase, small subunit - - - - - - - - - - - - - GHFFDFOM_00086 947981.E9LUP9_9CAUD 1.4e-78 250.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - GHFFDFOM_00087 947981.E9LUP9_9CAUD 0.0 993.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - GHFFDFOM_00088 1400520.LFAB_09115 2.33e-35 120.0 2DDZ9@1|root,2ZJX7@2|Bacteria,1W2BH@1239|Firmicutes,4I25Q@91061|Bacilli,3F8QY@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1056) - - - - - - - - - - - - DUF1056 GHFFDFOM_00089 1400520.LFAB_09110 8.48e-285 778.0 COG4695@1|root,COG4695@2|Bacteria,1UY1R@1239|Firmicutes,4HDQZ@91061|Bacilli,3FB4M@33958|Lactobacillaceae 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal GHFFDFOM_00090 947981.E9LUQ2_9CAUD 1.18e-164 462.0 4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPUI@28883|Caudovirales,4QKV6@10699|Siphoviridae 10699|Siphoviridae S Clp protease - - - - - - - - - - - - - GHFFDFOM_00091 278197.PEPE_1001 2.01e-269 740.0 COG4653@1|root,COG4653@2|Bacteria,1UACS@1239|Firmicutes,4HEAS@91061|Bacilli,3FB8A@33958|Lactobacillaceae 91061|Bacilli S Phage capsid family - - - - - - - - - - - - Phage_capsid GHFFDFOM_00092 278197.PEPE_1000 5.42e-64 196.0 2EI91@1|root,33C0D@2|Bacteria,1VP0M@1239|Firmicutes,4I0AJ@91061|Bacilli,3F87N@33958|Lactobacillaceae 91061|Bacilli S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 GHFFDFOM_00093 1400520.LFAB_09090 6.96e-76 226.0 2E799@1|root,331SU@2|Bacteria,1VJW9@1239|Firmicutes,4HPEE@91061|Bacilli,3F6F8@33958|Lactobacillaceae 91061|Bacilli S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join GHFFDFOM_00094 1400520.LFAB_09085 1.65e-88 260.0 2FCMI@1|root,344QS@2|Bacteria,1VYI2@1239|Firmicutes,4HYQ6@91061|Bacilli,3F87J@33958|Lactobacillaceae 91061|Bacilli S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like GHFFDFOM_00095 1400520.LFAB_09080 3.85e-76 228.0 2FK0I@1|root,34BNT@2|Bacteria,1W13M@1239|Firmicutes,4HYMN@91061|Bacilli,3F73N@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF806) - - - - - - - - - - - - DUF806 GHFFDFOM_00096 278197.PEPE_0996 3.23e-136 387.0 2F78C@1|root,33ZPM@2|Bacteria,1VXXI@1239|Firmicutes,4HWZC@91061|Bacilli,3F5N9@33958|Lactobacillaceae 91061|Bacilli S Phage tail tube protein - - - - - - - - - - - - Phage_TTP_1 GHFFDFOM_00097 278197.PEPE_0995 2.34e-76 228.0 2BSR6@1|root,32MU0@2|Bacteria,1U6I3@1239|Firmicutes,4IGAE@91061|Bacilli,3F7YI@33958|Lactobacillaceae 91061|Bacilli S Phage tail assembly chaperone proteins, TAC - - - - - - - - - - - - Phage_TAC_3 GHFFDFOM_00098 1400520.LFAB_09065 6.36e-34 116.0 2BC6G@1|root,325RA@2|Bacteria,1U6VI@1239|Firmicutes,4IGPF@91061|Bacilli,3F8JW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00099 1400520.LFAB_09060 0.0 1591.0 COG0791@1|root,COG3953@1|root,COG5283@1|root,COG5412@1|root,COG0791@2|Bacteria,COG3953@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,1UZN8@1239|Firmicutes,4HGQG@91061|Bacilli,3F3T2@33958|Lactobacillaceae 91061|Bacilli L Phage tail tape measure protein TP901 - - - - - - - - - - - - NLPC_P60,PhageMin_Tail,SLT GHFFDFOM_00100 947981.E9LUR2_9CAUD 0.0 1127.0 4QBF8@10239|Viruses,4QUS7@35237|dsDNA viruses no RNA stage,4QPI9@28883|Caudovirales,4QKN2@10699|Siphoviridae 10699|Siphoviridae S Phage tail protein - - - - - - - - - - - - - GHFFDFOM_00101 278197.PEPE_0991 0.0 1126.0 COG4926@1|root,COG4926@2|Bacteria,1V7K6@1239|Firmicutes,4HJ7J@91061|Bacilli,3F5SM@33958|Lactobacillaceae 91061|Bacilli S Phage minor structural protein - - - - - - - - - - - - Prophage_tail GHFFDFOM_00105 1400520.LFAB_09030 3.52e-71 215.0 2B254@1|root,31UNB@2|Bacteria,1UIXH@1239|Firmicutes,4I0AP@91061|Bacilli,3F55T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00106 1136177.KCA1_1105 2.9e-254 700.0 COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V16P@1239|Firmicutes,4HF99@91061|Bacilli,3FC13@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - - - - - - - - - - Glyco_hydro_25,LysM,SH3_5 GHFFDFOM_00107 1136177.KCA1_1106 1.78e-47 152.0 2C0XI@1|root,2ZJRZ@2|Bacteria,1W39V@1239|Firmicutes,4I12U@91061|Bacilli,3F7TU@33958|Lactobacillaceae 91061|Bacilli S Haemolysin XhlA - - - - - - - - - - - - XhlA GHFFDFOM_00108 220668.lp_2399 2.04e-50 163.0 COG5546@1|root,COG5546@2|Bacteria,1W4HU@1239|Firmicutes,4I17D@91061|Bacilli,3F6KT@33958|Lactobacillaceae 91061|Bacilli S Bacteriophage holin - - - - - - - - - - - - Phage_holin_1 GHFFDFOM_00110 220668.lp_2078 7.29e-285 779.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,3F9D5@33958|Lactobacillaceae 91061|Bacilli D Cell cycle protein rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE GHFFDFOM_00111 220668.lp_2077 0.0 1122.0 COG4986@1|root,COG4986@2|Bacteria,1TRRR@1239|Firmicutes,4HEN6@91061|Bacilli,3F4E8@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 GHFFDFOM_00112 60520.HR47_07735 1.23e-180 503.0 COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HF9R@91061|Bacilli,3FC3E@33958|Lactobacillaceae 91061|Bacilli P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - AAA_assoc_C,ABC_tran GHFFDFOM_00113 220668.lp_2075 9.64e-276 754.0 COG1316@1|root,COG1316@2|Bacteria,1TQ9C@1239|Firmicutes,4HB29@91061|Bacilli,3F5ZN@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-related transcriptional attenuator domain ywtF_2 - - - - - - - - - - - LytR_cpsA_psr GHFFDFOM_00114 220668.lp_2074 2.13e-113 327.0 COG2963@1|root,COG2963@2|Bacteria,1V1QC@1239|Firmicutes,4HH7E@91061|Bacilli,3F5BG@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain - - - - - - - - - - - - HTH_28,HTH_Tnp_1 GHFFDFOM_00116 220668.lp_2071 6.58e-226 622.0 COG1215@1|root,COG1215@2|Bacteria,1UI5W@1239|Firmicutes,4ISEQ@91061|Bacilli,3FBSD@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 csbB - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 GHFFDFOM_00117 220668.lp_2069 3.81e-87 256.0 29IMR@1|root,305J0@2|Bacteria,1U6QT@1239|Firmicutes,4IGI3@91061|Bacilli,3F8BS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00118 220668.lp_2068 1.01e-100 290.0 29NYQ@1|root,309WT@2|Bacteria,1U5V3@1239|Firmicutes,4IFIQ@91061|Bacilli,3F6IY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00119 220668.lp_2067 6.62e-278 760.0 COG3425@1|root,COG3425@2|Bacteria,1TR4K@1239|Firmicutes,4HA67@91061|Bacilli,3F425@33958|Lactobacillaceae 91061|Bacilli I Hydroxymethylglutaryl-CoA synthase mvaS - 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 - - - HMG_CoA_synt_C,HMG_CoA_synt_N GHFFDFOM_00120 220668.lp_2066 6.4e-122 350.0 28UQM@1|root,2ZGUY@2|Bacteria,1W3AZ@1239|Firmicutes,4I0YM@91061|Bacilli,3F65Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00121 220668.lp_2063 7.22e-149 419.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,3F3JG@33958|Lactobacillaceae 91061|Bacilli K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 GHFFDFOM_00122 1136177.KCA1_1750 7.68e-48 154.0 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,3F87S@33958|Lactobacillaceae 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 GHFFDFOM_00123 220668.lp_2061 3.96e-44 143.0 COG3763@1|root,COG3763@2|Bacteria,1VEJC@1239|Firmicutes,4HKMJ@91061|Bacilli,3F809@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0154) XK26_06720 - - ko:K09976 - - - - ko00000 - - - UPF0154 GHFFDFOM_00124 220668.lp_2060 8.8e-155 434.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,3F4QB@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase GHFFDFOM_00125 220668.lp_2059 3.4e-177 494.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,3F4C5@33958|Lactobacillaceae 91061|Bacilli L Methyltransferase small domain yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS GHFFDFOM_00126 220668.lp_2058 1.02e-66 202.0 COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli,3F7G2@33958|Lactobacillaceae 91061|Bacilli L GIY-YIG catalytic domain protein yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG GHFFDFOM_00127 220668.lp_2057 1.92e-239 658.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HCIS@91061|Bacilli,3F4US@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhD - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C GHFFDFOM_00128 220668.lp_2056 2.92e-172 480.0 COG1011@1|root,COG1011@2|Bacteria,1V5P7@1239|Firmicutes,4HHGY@91061|Bacilli,3F5CR@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2 GHFFDFOM_00129 220668.lp_2055 3.66e-184 513.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,3F3M1@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 GHFFDFOM_00130 220668.lp_2054 1.88e-194 541.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,3F459@33958|Lactobacillaceae 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS GHFFDFOM_00131 220668.lp_2053 3.01e-165 462.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,3F42J@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase GHFFDFOM_00132 220668.lp_2052 9.83e-113 325.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,3F4X2@33958|Lactobacillaceae 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF GHFFDFOM_00133 220668.lp_2051 3.17e-190 527.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,3F42M@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf GHFFDFOM_00134 220668.lp_2050 1.13e-175 491.0 COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,4IV81@91061|Bacilli,3F4AF@33958|Lactobacillaceae 91061|Bacilli I Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 GHFFDFOM_00135 220668.lp_2049 4.64e-294 804.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,3F3TM@33958|Lactobacillaceae 91061|Bacilli M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 GHFFDFOM_00136 220668.lp_2048 0.0 1126.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,3F44A@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit GHFFDFOM_00137 220668.lp_2045 0.0 2875.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,3F4AN@33958|Lactobacillaceae 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon GHFFDFOM_00138 220668.lp_2044 9.74e-108 310.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,3F6GZ@33958|Lactobacillaceae 91061|Bacilli J Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C GHFFDFOM_00139 220668.lp_2043 4.46e-275 754.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,3F3KZ@33958|Lactobacillaceae 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 GHFFDFOM_00140 220668.lp_2042 2.95e-65 198.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,3F7E2@33958|Lactobacillaceae 91061|Bacilli K Protein of unknown function (DUF448) ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 GHFFDFOM_00141 220668.lp_2041 3.28e-63 193.0 COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,3F7ZK@33958|Lactobacillaceae 91061|Bacilli J ribosomal protein ylxQ - - - - - - - - - - - Ribosomal_L7Ae GHFFDFOM_00142 220668.lp_2040 0.0 1275.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,3F3JV@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N GHFFDFOM_00143 1136177.KCA1_1729 3.04e-71 215.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,3F6WZ@33958|Lactobacillaceae 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA GHFFDFOM_00144 220668.lp_2038 0.0 925.0 COG1605@1|root,COG2271@1|root,COG1605@2|Bacteria,COG2271@2|Bacteria,1V18N@1239|Firmicutes,4IPXQ@91061|Bacilli,3FBEJ@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator - - - - - - - - - - - - CM_2,MFS_1 GHFFDFOM_00145 220668.lp_2037 2.12e-274 751.0 COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli,3F502@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt GHFFDFOM_00146 220668.lp_2036 9.84e-123 350.0 2E0PE@1|root,32W87@2|Bacteria,1VC0E@1239|Firmicutes,4HKI6@91061|Bacilli,3F60R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00147 220668.lp_2035 8.18e-303 827.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,3F5B2@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase GHFFDFOM_00148 220668.lp_2034 1.47e-246 679.0 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli,3F589@33958|Lactobacillaceae 91061|Bacilli E prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22610 ACT,PDH GHFFDFOM_00149 220668.lp_2033 1.45e-114 329.0 COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,4HKD6@91061|Bacilli,3F7FE@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI GHFFDFOM_00150 220668.lp_2032 5.17e-220 607.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,3F3NX@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N GHFFDFOM_00151 220668.lp_2031 6.48e-243 667.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,3F3TG@33958|Lactobacillaceae 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase GHFFDFOM_00152 220668.lp_2030 1.19e-169 473.0 COG3527@1|root,COG3527@2|Bacteria,1V4AH@1239|Firmicutes,4HJ98@91061|Bacilli,3FCCX@33958|Lactobacillaceae 91061|Bacilli Q Alpha-acetolactate decarboxylase budA - 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 - R02948 RC00812 ko00000,ko00001,ko01000 - - - AAL_decarboxy GHFFDFOM_00153 220668.lp_2029 4.42e-248 681.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,3F3ST@33958|Lactobacillaceae 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg GHFFDFOM_00154 220668.lp_2028 4.52e-111 322.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,3F4DY@33958|Lactobacillaceae 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE GHFFDFOM_00155 220668.lp_2027 0.0 1168.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,3F48C@33958|Lactobacillaceae 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 GHFFDFOM_00156 220668.lp_2026 2.54e-266 730.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,3F490@33958|Lactobacillaceae 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG GHFFDFOM_00157 220668.lp_2021 4.21e-266 730.0 COG1680@1|root,COG1680@2|Bacteria,1V0GX@1239|Firmicutes,4HCXH@91061|Bacilli,3F4TH@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpX2 - - - - - - - - - - - Beta-lactamase GHFFDFOM_00158 220668.lp_2020 8.59e-27 97.8 2DKST@1|root,30APB@2|Bacteria,1U6XZ@1239|Firmicutes,4IGS5@91061|Bacilli,3F8PK@33958|Lactobacillaceae 91061|Bacilli S D-Ala-teichoic acid biosynthesis protein dltX - - - - - - - - - - - DUF3687 GHFFDFOM_00159 220668.lp_2019 0.0 1028.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,3F49R@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - AMP-binding,AMP-binding_C GHFFDFOM_00160 220668.lp_2018 1.14e-297 811.0 COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,3F4KK@33958|Lactobacillaceae 91061|Bacilli M MBOAT, membrane-bound O-acyltransferase family dltB - - ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - MBOAT GHFFDFOM_00161 220668.lp_2017 5.75e-47 150.0 COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli,3F7Q1@33958|Lactobacillaceae 91061|Bacilli J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - PP-binding GHFFDFOM_00162 220668.lp_2016 1.68e-312 850.0 COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli,3F3WE@33958|Lactobacillaceae 91061|Bacilli M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) dltD - - ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - DltD GHFFDFOM_00163 220668.lp_2015 0.0 1187.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,3F3Z1@33958|Lactobacillaceae 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C GHFFDFOM_00164 220668.lp_1994 1.73e-67 204.0 29P3S@1|root,30A1Z@2|Bacteria,1U633@1239|Firmicutes,4IFSC@91061|Bacilli,3F6XC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00165 220668.lp_1992 4.78e-65 197.0 2FCQV@1|root,344U2@2|Bacteria,1W026@1239|Firmicutes,4HZ7F@91061|Bacilli,3F7FM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00166 220668.lp_1991 1.06e-145 410.0 COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,4HG5E@91061|Bacilli,3F59D@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA glycosylase MPG family yxlJ GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco GHFFDFOM_00167 220668.lp_1990 1.68e-225 621.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,3F47Z@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA GHFFDFOM_00168 220668.lp_1989 3.13e-172 481.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,3F64Z@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA GHFFDFOM_00169 220668.lp_1988 2.56e-76 227.0 2DKNW@1|root,30A40@2|Bacteria,1U65T@1239|Firmicutes,4IFVP@91061|Bacilli,3F74W@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00170 220668.lp_1987 0.0 1446.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,3F44F@33958|Lactobacillaceae 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS GHFFDFOM_00171 220668.lp_1986 8.2e-102 295.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,3F6GK@33958|Lactobacillaceae 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase GHFFDFOM_00172 220668.lp_1985 1.35e-147 415.0 COG0546@1|root,COG0546@2|Bacteria,1V3DR@1239|Firmicutes,4HGMU@91061|Bacilli,3F741@33958|Lactobacillaceae 91061|Bacilli J HAD-hyrolase-like yjcF - - - - - - - - - - - HAD_2 GHFFDFOM_00173 220668.lp_1983 1.87e-213 588.0 COG3001@1|root,COG3001@2|Bacteria,1V1VZ@1239|Firmicutes,4HGP7@91061|Bacilli,3FCE0@33958|Lactobacillaceae 91061|Bacilli G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin GHFFDFOM_00174 220668.lp_1982 2.32e-199 552.0 COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG4991@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,3F4F4@33958|Lactobacillaceae 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3 GHFFDFOM_00175 220668.lp_1981 2.47e-310 845.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,3F3M3@33958|Lactobacillaceae 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His GHFFDFOM_00176 220668.lp_1980 0.0 1202.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,3F4PE@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon GHFFDFOM_00177 220668.lp_1979 3.98e-124 353.0 COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,3F3YI@33958|Lactobacillaceae 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR GHFFDFOM_00178 220668.lp_1978 4.35e-204 565.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,3F3PH@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 yitT - - - - - - - - - - - DUF2179,YitT_membrane GHFFDFOM_00179 220668.lp_1977 1.84e-284 776.0 COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,4HBID@91061|Bacilli,3F456@33958|Lactobacillaceae 91061|Bacilli M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase tagB - 2.7.8.44 ko:K21285 - - R11558 RC00078 ko00000,ko01000 - - iYO844.BSU35760 Glyphos_transf GHFFDFOM_00180 220668.lp_1976 1.42e-217 600.0 COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,4HB4F@91061|Bacilli,3F42I@33958|Lactobacillaceae 91061|Bacilli L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 GHFFDFOM_00181 220668.lp_1975 3.65e-166 465.0 COG1028@1|root,COG1028@2|Bacteria,1UZ4M@1239|Firmicutes,4HC3Z@91061|Bacilli,3FBRG@33958|Lactobacillaceae 91061|Bacilli C Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 GHFFDFOM_00182 220668.lp_1974 2.32e-194 539.0 COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,3F3WK@33958|Lactobacillaceae 91061|Bacilli F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation yqfL - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase GHFFDFOM_00183 1136177.KCA1_1688 1.09e-30 108.0 COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli,3F81Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 GHFFDFOM_00184 220668.lp_1972 9.21e-94 274.0 COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,3F6I0@33958|Lactobacillaceae 91061|Bacilli S YqeY-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY GHFFDFOM_00185 220668.lp_1970 4.81e-229 631.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,3F4E7@33958|Lactobacillaceae 91061|Bacilli T phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH GHFFDFOM_00186 220668.lp_1969 1.28e-108 313.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,3F516@33958|Lactobacillaceae 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 GHFFDFOM_00187 220668.lp_1968 1.15e-94 276.0 COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,3F7DC@33958|Lactobacillaceae 91061|Bacilli M Diacylglycerol kinase dgkA - 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSB619.SA_RS07900 DAGK_prokar GHFFDFOM_00188 220668.lp_1967 7.92e-217 598.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,3F3WQ@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 GHFFDFOM_00189 220668.lp_1966 2.84e-189 525.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli,3F56P@33958|Lactobacillaceae 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N GHFFDFOM_00190 220668.lp_1965 8.64e-224 615.0 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli,3F3T8@33958|Lactobacillaceae 91061|Bacilli J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e GHFFDFOM_00191 220668.lp_1964 0.0 1350.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli,3F4G8@33958|Lactobacillaceae 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f GHFFDFOM_00192 220668.lp_1963 0.0 1221.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,3F3N1@33958|Lactobacillaceae 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 GHFFDFOM_00193 220668.lp_1962 1.74e-251 691.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,3F4CF@33958|Lactobacillaceae 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 GHFFDFOM_00194 220668.lp_1959 6.86e-85 250.0 COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,3F7AX@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor ytrA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR GHFFDFOM_00195 220668.lp_1958 2.45e-213 589.0 COG1131@1|root,COG1131@2|Bacteria,1TS5Y@1239|Firmicutes,4HBUA@91061|Bacilli,3F4BF@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_00196 220668.lp_1957 8.67e-255 699.0 29P86@1|root,30A68@2|Bacteria,1U692@1239|Firmicutes,4IG07@91061|Bacilli,3F7C4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00197 220668.lp_1956 6.08e-253 694.0 29PBN@1|root,30A9W@2|Bacteria,1U6DM@1239|Firmicutes,4IG5C@91061|Bacilli,3F7NR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00198 220668.lp_1955 2.02e-168 471.0 COG1277@1|root,COG1277@2|Bacteria,1V1GX@1239|Firmicutes,4HG2P@91061|Bacilli,3F52P@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_4 GHFFDFOM_00199 220668.lp_1954 4.36e-208 576.0 COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,3F3YW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_00200 1321779.HMPREF1984_00059 0.000138 46.6 28NY7@1|root,2ZBVG@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2992) yjdF - - - - - - - - - - - DUF2992 GHFFDFOM_00201 220668.lp_1949 1.28e-148 419.0 COG2364@1|root,COG2364@2|Bacteria,1UXHA@1239|Firmicutes,4HG9V@91061|Bacilli,3F6Z6@33958|Lactobacillaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - GHFFDFOM_00202 220668.lp_1948 5.9e-103 298.0 COG1846@1|root,COG1846@2|Bacteria,1U6DA@1239|Firmicutes,4IG51@91061|Bacilli,3F7NB@33958|Lactobacillaceae 91061|Bacilli K MarR family - - - - - - - - - - - - MarR,MarR_2 GHFFDFOM_00203 220668.lp_1947 6.64e-109 313.0 COG0454@1|root,COG0454@2|Bacteria,1UI5X@1239|Firmicutes,4HWD1@91061|Bacilli,3FBSE@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - ko:K03827 - - - - ko00000,ko01000 - - - Acetyltransf_10 GHFFDFOM_00205 220668.lp_1945 3.43e-203 563.0 COG1131@1|root,COG1131@2|Bacteria,1TRM5@1239|Firmicutes,4HFBN@91061|Bacilli,3FC3M@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yvfR - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_00206 220668.lp_1944 7.05e-172 481.0 COG0842@1|root,COG0842@2|Bacteria,1V7QG@1239|Firmicutes,4HFU4@91061|Bacilli,3F5Q7@33958|Lactobacillaceae 91061|Bacilli V ABC-2 type transporter XK27_09830 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 GHFFDFOM_00207 220668.lp_1943 1.91e-261 716.0 COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli,3F3VR@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 GHFFDFOM_00208 220668.lp_1942 1.11e-134 382.0 COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli,3F4VH@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Lux Regulon desR - - ko:K02479,ko:K07693 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg GHFFDFOM_00209 220668.lp_1941 0.0 942.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4IF8P@91061|Bacilli,3F5ZI@33958|Lactobacillaceae 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain nox4 - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim GHFFDFOM_00211 220668.lp_1939 7.96e-223 614.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,3F4EJ@33958|Lactobacillaceae 91061|Bacilli C nadph quinone reductase cryZ - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 GHFFDFOM_00212 220668.lp_1938 1.41e-207 574.0 COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,4HAZB@91061|Bacilli,3F3VP@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_00213 220668.lp_1937 1.22e-101 294.0 COG4334@1|root,COG4334@2|Bacteria,1VBEN@1239|Firmicutes,4HM8H@91061|Bacilli,3F75W@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2255) - - - - - - - - - - - - DUF2255 GHFFDFOM_00214 220668.lp_1936 1.02e-145 411.0 COG0702@1|root,COG0702@2|Bacteria,1VS7E@1239|Firmicutes,4HT7A@91061|Bacilli,3F5Q2@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 GHFFDFOM_00215 220668.lp_1935 1.12e-207 573.0 COG4814@1|root,COG4814@2|Bacteria,1VSYU@1239|Firmicutes,4HU15@91061|Bacilli,3F4J2@33958|Lactobacillaceae 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - DUF915 GHFFDFOM_00216 220668.lp_1934 1.01e-166 466.0 COG1737@1|root,COG1737@2|Bacteria,1TS9A@1239|Firmicutes,4HCBF@91061|Bacilli,3F6D3@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS GHFFDFOM_00217 220668.lp_1933 2.59e-129 369.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,3F47V@33958|Lactobacillaceae 91061|Bacilli S Maltose O-acetyltransferase thgA3 - 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac GHFFDFOM_00218 220668.lp_1932 1.97e-152 429.0 COG0546@1|root,COG0546@2|Bacteria,1UYBR@1239|Firmicutes,4IPXP@91061|Bacilli 91061|Bacilli S haloacid dehalogenase-like hydrolase - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 GHFFDFOM_00219 220668.lp_1931 0.0 1123.0 COG4715@1|root,COG4715@2|Bacteria,1TS1R@1239|Firmicutes 1239|Firmicutes S Zinc finger, swim domain protein - - - - - - - - - - - - SWIM GHFFDFOM_00220 220668.lp_1930 5.7e-146 411.0 COG0702@1|root,COG0702@2|Bacteria 2|Bacteria GM epimerase - - - - - - - - - - - - 3Beta_HSD,Epimerase,NAD_binding_10,NmrA GHFFDFOM_00221 220668.lp_1929 1.56e-90 265.0 COG3272@1|root,COG3272@2|Bacteria,1VGGK@1239|Firmicutes,4HP7S@91061|Bacilli,3F7CK@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722 GHFFDFOM_00222 220668.lp_1928 3.1e-92 269.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F660@33958|Lactobacillaceae 91061|Bacilli P ArsC family spx2 - - ko:K16509 - - - - ko00000 - - - ArsC GHFFDFOM_00223 220668.lp_1927 9.89e-138 390.0 COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,4HHQT@91061|Bacilli,3F4BS@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain yjhB - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,Nudix_N GHFFDFOM_00224 220668.lp_1926 5.87e-177 493.0 COG1349@1|root,COG1349@2|Bacteria,1V1VH@1239|Firmicutes,4HG12@91061|Bacilli,3F3UT@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR GHFFDFOM_00225 220668.lp_1925 0.0 1081.0 COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli,3FBSF@33958|Lactobacillaceae 91061|Bacilli P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain nox - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,Rhodanese GHFFDFOM_00226 220668.lp_1923 1.36e-266 731.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 GHFFDFOM_00227 220668.lp_1922 4.38e-102 295.0 COG1846@1|root,COG1846@2|Bacteria,1VMZX@1239|Firmicutes,4HMTC@91061|Bacilli,3F82U@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_27,MarR,MarR_2 GHFFDFOM_00228 220668.lp_1921 1.54e-305 836.0 COG0477@1|root,COG2223@1|root,COG2223@2|Bacteria,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3FCCM@33958|Lactobacillaceae 91061|Bacilli U Major Facilitator Superfamily - - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 GHFFDFOM_00229 220668.lp_1920 1.09e-310 846.0 COG0148@1|root,COG0148@2|Bacteria,1V12I@1239|Firmicutes,4HTD2@91061|Bacilli,3FCCA@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0043236,GO:0050840 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N GHFFDFOM_00230 220668.lp_1919 0.0 1409.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HVA4@91061|Bacilli,3F55J@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus - - - - - - - - - - - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase GHFFDFOM_00231 220668.lp_1918 4.32e-232 639.0 COG0604@1|root,COG0604@2|Bacteria,1TPGA@1239|Firmicutes,4HER3@91061|Bacilli,3F4HK@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 GHFFDFOM_00232 220668.lp_1916 6.09e-281 766.0 COG1835@1|root,COG1835@2|Bacteria,1V7GP@1239|Firmicutes,4HJ4R@91061|Bacilli,3F42R@33958|Lactobacillaceae 91061|Bacilli I transferase activity, transferring acyl groups other than amino-acyl groups - - - - - - - - - - - - Acyl_transf_3 GHFFDFOM_00233 220668.lp_1915 5.78e-268 734.0 2C353@1|root,309Q7@2|Bacteria,1U5H7@1239|Firmicutes,4IF82@91061|Bacilli,3F5XZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00234 220668.lp_1914 7.43e-119 340.0 COG1846@1|root,COG1846@2|Bacteria,1VIXS@1239|Firmicutes,4HPYM@91061|Bacilli,3FC7J@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein yetL GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR GHFFDFOM_00235 220668.lp_1913 1.94e-83 246.0 COG0607@1|root,COG0607@2|Bacteria,1VJIW@1239|Firmicutes,4HW5V@91061|Bacilli,3F707@33958|Lactobacillaceae 91061|Bacilli P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese GHFFDFOM_00236 220668.lp_1912 0.0 1580.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4ISER@91061|Bacilli,3F3U1@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate pps - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N GHFFDFOM_00237 220668.lp_1911 2.74e-112 323.0 COG1846@1|root,COG1846@2|Bacteria,1V40V@1239|Firmicutes,4HI52@91061|Bacilli,3F5C5@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR,MarR_2 GHFFDFOM_00238 220668.lp_1910 3.85e-209 580.0 COG1131@1|root,COG1131@2|Bacteria,1TPJE@1239|Firmicutes,4HB5U@91061|Bacilli,3F58G@33958|Lactobacillaceae 91061|Bacilli V ABC transporter drrA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 GHFFDFOM_00239 220668.lp_1909 8.81e-166 465.0 COG0842@1|root,COG0842@2|Bacteria,1TS7U@1239|Firmicutes,4HCH1@91061|Bacilli,3F57J@33958|Lactobacillaceae 91061|Bacilli U ABC-2 type transporter drrB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane GHFFDFOM_00240 220668.lp_1908 5.84e-294 801.0 COG3307@1|root,COG3307@2|Bacteria,1V8CF@1239|Firmicutes,4IF0T@91061|Bacilli,3F59M@33958|Lactobacillaceae 91061|Bacilli M O-Antigen ligase - - - - - - - - - - - - Wzy_C GHFFDFOM_00241 220668.lp_1906 8.34e-165 461.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,3F4GT@33958|Lactobacillaceae 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK GHFFDFOM_00242 220668.lp_1905 1.61e-251 689.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,3F3ZD@33958|Lactobacillaceae 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 GHFFDFOM_00243 220668.lp_1904 3.17e-299 816.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli,3F45V@33958|Lactobacillaceae 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides pepT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M42 GHFFDFOM_00244 220668.lp_1903 0.0 1651.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,3F3RV@33958|Lactobacillaceae 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N GHFFDFOM_00245 60520.HR47_08375 2.02e-39 130.0 2DGWH@1|root,2ZXI7@2|Bacteria,1W2U5@1239|Firmicutes,4I0PU@91061|Bacilli,3F8TZ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2929) - - - - - - - - - - - - DUF2929 GHFFDFOM_00246 220668.lp_1899 0.0 2160.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,3F4AM@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon GHFFDFOM_00247 220668.lp_1898 8.69e-230 632.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli,3F4CC@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - iYO844.BSU29190 PFK GHFFDFOM_00248 220668.lp_1897 0.0 1123.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,3F3JU@33958|Lactobacillaceae 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C GHFFDFOM_00249 220668.lp_1894 2.51e-98 286.0 COG2707@1|root,COG2707@2|Bacteria,1V7JN@1239|Firmicutes,4HINS@91061|Bacilli,3F68U@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF441) ytwI - - - - - - - - - - - DUF441 GHFFDFOM_00250 220668.lp_1893 3.23e-217 598.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli,3F44W@33958|Lactobacillaceae 91061|Bacilli S S1 domain yitL - - ko:K00243 - - - - ko00000 - - - S1_2 GHFFDFOM_00251 220668.lp_1892 3.13e-211 584.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae 91061|Bacilli D recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase GHFFDFOM_00252 220668.lp_1891 3.99e-92 268.0 COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,3F7QC@33958|Lactobacillaceae 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ribT - - ko:K02859 - - - - ko00000 - - - Acetyltransf_1 GHFFDFOM_00253 220668.lp_1890 1.18e-174 488.0 COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,3FCCZ@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA GHFFDFOM_00254 220668.lp_1889 1.3e-132 377.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,3F5RN@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB GHFFDFOM_00255 220668.lp_1888 4.46e-166 464.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,3F402@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 GHFFDFOM_00256 220668.lp_1887 2.24e-126 360.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,3F4HD@33958|Lactobacillaceae 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt GHFFDFOM_00257 220668.lp_1886 3.38e-252 691.0 COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HJ71@91061|Bacilli,3F45N@33958|Lactobacillaceae 91061|Bacilli S Helix-turn-helix domain - - - - - - - - - - - - HTH_40 GHFFDFOM_00258 220668.lp_1885 0.0 936.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,3F4PY@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase RecQ recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind GHFFDFOM_00259 220668.lp_1884 1.25e-39 142.0 COG1388@1|root,COG1388@2|Bacteria,1VFEU@1239|Firmicutes,4HNW5@91061|Bacilli,3F6WV@33958|Lactobacillaceae 91061|Bacilli M Lysin motif - - - - - - - - - - - - LysM GHFFDFOM_00260 220668.lp_1883 1.27e-151 427.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,3F3W4@33958|Lactobacillaceae 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin GHFFDFOM_00261 220668.lp_1882 1.98e-281 772.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,3F4DQ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 GHFFDFOM_00262 220668.lp_1881 2.06e-314 856.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,3F4V0@33958|Lactobacillaceae 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 GHFFDFOM_00263 1400520.LFAB_08160 5.57e-55 172.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,3F6YN@33958|Lactobacillaceae 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding GHFFDFOM_00264 220668.lp_1877 7.1e-292 798.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,3F3ND@33958|Lactobacillaceae 91061|Bacilli S Tetratricopeptide repeat protein XK27_05225 - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 GHFFDFOM_00265 220668.lp_1876 1.29e-192 534.0 COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,4HWAW@91061|Bacilli,3F3Z7@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 GHFFDFOM_00266 220668.lp_1874 5.66e-185 514.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,3F3MA@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N GHFFDFOM_00267 220668.lp_1873 8.58e-290 791.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,3F3VH@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 GHFFDFOM_00268 220668.lp_1872 6.46e-109 313.0 2A42J@1|root,30SMC@2|Bacteria,1V54W@1239|Firmicutes,4HGI5@91061|Bacilli,3F3R1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00269 220668.lp_1871 0.0 1224.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,3FC7W@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn GHFFDFOM_00270 220668.lp_1870 4.04e-242 663.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,3F3SB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt GHFFDFOM_00271 220668.lp_1869 1.8e-119 340.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,3F6Y4@33958|Lactobacillaceae 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 GHFFDFOM_00272 220668.lp_1868 2.03e-189 527.0 COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli,3F4CW@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family WQ51_01275 - - - - - - - - - - - DegV GHFFDFOM_00273 220668.lp_1867 1.02e-209 581.0 COG2755@1|root,COG2755@2|Bacteria,1V1HR@1239|Firmicutes,4HDXS@91061|Bacilli,3F4N0@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase XK27_03630 - - - - - - - - - - - Lipase_GDSL_2 GHFFDFOM_00274 220668.lp_1866 3.29e-147 415.0 COG4698@1|root,COG4698@2|Bacteria,1VF0K@1239|Firmicutes,4HIYN@91061|Bacilli,3F5K5@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2140) ypmS - - - - - - - - - - - DUF2140 GHFFDFOM_00275 220668.lp_1865 9.33e-48 152.0 COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli,3F7ZP@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0346 family yozE - - - - - - - - - - - YozE_SAM_like GHFFDFOM_00276 220668.lp_1864 0.0 938.0 COG0793@1|root,COG3409@1|root,COG0793@2|Bacteria,COG3409@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,3F3SS@33958|Lactobacillaceae 91061|Bacilli M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 GHFFDFOM_00277 220668.lp_1863 0.0 886.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator qacA - - - - - - - - - - - MFS_1 GHFFDFOM_00278 220668.lp_1860 2.89e-251 689.0 COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,3F4KZ@33958|Lactobacillaceae 91061|Bacilli C Luciferase-like monooxygenase XK27_00915 - - - - - - - - - - - Bac_luciferase GHFFDFOM_00279 220668.lp_1859 5.85e-159 446.0 COG2085@1|root,COG2085@2|Bacteria,1V5YV@1239|Firmicutes,4HH6T@91061|Bacilli,3F4G0@33958|Lactobacillaceae 91061|Bacilli S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored GHFFDFOM_00280 60520.HR47_03060 4.62e-253 696.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - ko:K08153,ko:K19576 - M00717 - - ko00000,ko00002,ko02000 2.A.1.2.10,2.A.1.2.8 - - MFS_1 GHFFDFOM_00281 60520.HR47_03055 1.49e-222 613.0 COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,4HC5J@91061|Bacilli,3F4VM@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LysR family cpsY - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_00282 220668.lp_1856 5.13e-292 795.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,3F58A@33958|Lactobacillaceae 91061|Bacilli E Methionine synthase XK27_05470 - - - - - - - - - - - Meth_synt_2 GHFFDFOM_00284 220668.lp_1854 2.25e-207 573.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,3F3MI@33958|Lactobacillaceae 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 GHFFDFOM_00285 220668.lp_1853 5e-176 491.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,3F3JC@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII GHFFDFOM_00286 220668.lp_1852 8.11e-203 561.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,3F41U@33958|Lactobacillaceae 91061|Bacilli LU DNA protecting protein DprA dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A GHFFDFOM_00287 220668.lp_1850 0.0 1389.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,3F3VS@33958|Lactobacillaceae 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom GHFFDFOM_00288 220668.lp_1848 0.0 864.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,3F3WW@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA GHFFDFOM_00289 220668.lp_1847 1.5e-227 626.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,3F44K@33958|Lactobacillaceae 91061|Bacilli D Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase GHFFDFOM_00290 1136177.KCA1_1594 6.84e-121 345.0 COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H9PD@91061|Bacilli,3F4HS@33958|Lactobacillaceae 91061|Bacilli O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome GHFFDFOM_00291 220668.lp_1845 0.0 893.0 COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,3F3WB@33958|Lactobacillaceae 91061|Bacilli O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small GHFFDFOM_00292 220668.lp_1843 1.27e-217 599.0 COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,4HA4J@91061|Bacilli,3F3KT@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase lacX - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim GHFFDFOM_00293 220668.lp_1842 2.4e-137 389.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,3F543@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf GHFFDFOM_00294 220668.lp_1840 0.0 1306.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,3F430@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim GHFFDFOM_00295 220668.lp_1839 0.0 1594.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,3F3MJ@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV GHFFDFOM_00296 220668.lp_1838 3.82e-228 628.0 COG0583@1|root,COG0583@2|Bacteria,1UYS5@1239|Firmicutes,4HF07@91061|Bacilli,3F48B@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_00297 220668.lp_1837 3.91e-216 597.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,3F3PJ@33958|Lactobacillaceae 91061|Bacilli C inorganic pyrophosphatase ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 GHFFDFOM_00298 220668.lp_1836 3.8e-105 303.0 COG0229@1|root,COG0229@2|Bacteria,1UPN0@1239|Firmicutes,4HGWN@91061|Bacilli,3F6H4@33958|Lactobacillaceae 91061|Bacilli O peptide methionine sulfoxide reductase msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR GHFFDFOM_00299 220668.lp_1835 9.17e-126 357.0 COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,3F3YI@33958|Lactobacillaceae 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR GHFFDFOM_00300 220668.lp_1834 1.07e-43 141.0 29PF4@1|root,30ADA@2|Bacteria,1U6HN@1239|Firmicutes,4IG9Y@91061|Bacilli,3F7XW@33958|Lactobacillaceae 91061|Bacilli S YozE SAM-like fold - - - - - - - - - - - - YozE_SAM_like GHFFDFOM_00301 220668.lp_1833 2.08e-203 563.0 COG4974@1|root,COG4974@2|Bacteria,1UFH8@1239|Firmicutes,4IES1@91061|Bacilli,3F3KV@33958|Lactobacillaceae 91061|Bacilli L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Phage_int_SAM_1,Phage_int_SAM_4 GHFFDFOM_00302 220668.lp_1825 0.0 963.0 COG1807@1|root,COG1807@2|Bacteria,1VCF5@1239|Firmicutes,4HQ4B@91061|Bacilli,3F615@33958|Lactobacillaceae 91061|Bacilli M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 GHFFDFOM_00303 220668.lp_1824 2.78e-309 843.0 COG1215@1|root,COG1215@2|Bacteria,1VX75@1239|Firmicutes,4HX3T@91061|Bacilli,3FC15@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family group 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3 GHFFDFOM_00304 220668.lp_1823 1.98e-66 204.0 29PND@1|root,30AKK@2|Bacteria,1U6TS@1239|Firmicutes,4IGMK@91061|Bacilli,3F8H3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00305 220668.lp_1822 5.33e-303 828.0 COG1249@1|root,COG1249@2|Bacteria,1TS0Z@1239|Firmicutes,4HBYB@91061|Bacilli,3F3K2@33958|Lactobacillaceae 91061|Bacilli C Glutathione reductase gshR1 - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim GHFFDFOM_00306 220668.lp_1821 1.87e-92 271.0 COG1846@1|root,COG1846@2|Bacteria,1VBNV@1239|Firmicutes,4HMCJ@91061|Bacilli,3F70R@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR GHFFDFOM_00307 220668.lp_1820 1.34e-120 344.0 COG0454@1|root,COG0456@2|Bacteria,1V1RG@1239|Firmicutes,4HFN7@91061|Bacilli,3F73H@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain paiA GO:0003674,GO:0003824,GO:0004145,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0043937,GO:0043939,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0065007 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 GHFFDFOM_00308 220668.lp_1819 0.0 1267.0 COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,4IPPR@91061|Bacilli,3FBDI@33958|Lactobacillaceae 91061|Bacilli H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase tarL - 2.7.8.14,2.7.8.47 ko:K18704 - - R11614,R11621 - ko00000,ko01000 - - - Glyphos_transf GHFFDFOM_00309 220668.lp_1818 9.65e-272 743.0 COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,4HBRD@91061|Bacilli,3F4WC@33958|Lactobacillaceae 91061|Bacilli H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase tarK - 2.7.8.14,2.7.8.46,2.7.8.47 ko:K18704,ko:K21592 - - R11613,R11614,R11621 - ko00000,ko01000 - - - Glycos_transf_2,Glyphos_transf GHFFDFOM_00310 220668.lp_1817 2.65e-246 676.0 COG1063@1|root,COG1063@2|Bacteria,1TQSR@1239|Firmicutes,4HCCH@91061|Bacilli,3F4VQ@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate tarJ - 1.1.1.137,1.1.1.405 ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 - R01524,R01525 RC00089 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,Glu_dehyd_C GHFFDFOM_00311 220668.lp_1816 2.13e-151 426.0 COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HFH7@91061|Bacilli,3F4WQ@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate tarI GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.40,2.7.7.60 ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R02921,R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD GHFFDFOM_00312 220668.lp_1815 8.23e-291 798.0 29UYR@1|root,30GBR@2|Bacteria,1UFPM@1239|Firmicutes,4IEVQ@91061|Bacilli,3F4MC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00313 220668.lp_1814 0.0 964.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,3F4EG@33958|Lactobacillaceae 91061|Bacilli C L-lactate permease lctP - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm GHFFDFOM_00314 220668.lp_1813 7.79e-78 231.0 2A40M@1|root,30SJ5@2|Bacteria,1U65D@1239|Firmicutes,4IFV6@91061|Bacilli,3F73D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00315 220668.lp_1812 1.85e-174 490.0 2BVD0@1|root,32QT1@2|Bacteria,1V3YR@1239|Firmicutes,4HK85@91061|Bacilli,3F67T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00316 220668.lp_1811 1.23e-311 850.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease aapA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease GHFFDFOM_00317 220668.lp_1809 2.59e-177 497.0 COG2035@1|root,COG2035@2|Bacteria,1UYD5@1239|Firmicutes,4HBE3@91061|Bacilli,3F4QH@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF368) XK27_00890 - - ko:K08974 - - - - ko00000 - - - DUF368 GHFFDFOM_00318 220668.lp_1807 2.98e-166 467.0 COG4420@1|root,COG4420@2|Bacteria,1V46X@1239|Firmicutes,4HI49@91061|Bacilli,3F4FJ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1003) yejC - - - - - - - - - - - DUF1003 GHFFDFOM_00319 220668.lp_1806 5.42e-67 203.0 2ED3T@1|root,3370N@2|Bacteria,1VIJK@1239|Firmicutes,4HPGM@91061|Bacilli,3F765@33958|Lactobacillaceae 91061|Bacilli S Staphylococcal protein of unknown function (DUF960) XK27_08430 - - - - - - - - - - - DUF960 GHFFDFOM_00321 220668.lp_1803 3.87e-264 726.0 COG0477@1|root,COG2814@2|Bacteria,1UZKT@1239|Firmicutes,4HDHS@91061|Bacilli,3F4QJ@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily pmrB - - - - - - - - - - - MFS_1 GHFFDFOM_00322 220668.lp_1801 6.64e-189 524.0 COG1085@1|root,COG1085@2|Bacteria,1TSNU@1239|Firmicutes,4H9TY@91061|Bacilli,3F3JH@33958|Lactobacillaceae 91061|Bacilli C Domain of unknown function (DUF4931) - - - - - - - - - - - - DUF4931 GHFFDFOM_00323 220668.lp_1800 1.23e-63 194.0 2A1CK@1|root,30PJJ@2|Bacteria,1U682@1239|Firmicutes,4IFYS@91061|Bacilli,3F7A1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00324 220668.lp_1799 1.72e-28 115.0 2C6I8@1|root,309UV@2|Bacteria,1U5RH@1239|Firmicutes,4IFFN@91061|Bacilli,3F6DF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00325 220668.lp_1798 2.9e-170 476.0 COG5523@1|root,COG5523@2|Bacteria,1VCPB@1239|Firmicutes,4HN1D@91061|Bacilli,3F69G@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF975) - - - - - - - - - - - - DUF975 GHFFDFOM_00326 220668.lp_1797 2.47e-101 293.0 COG2153@1|root,COG2153@2|Bacteria 2|Bacteria K protein acetylation yjcF - 3.5.4.33,4.4.1.8 ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941,R10223 RC00056,RC00069,RC00382,RC00477,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007,ko03016 - - - Acetyltransf_10 GHFFDFOM_00327 220668.lp_1796 1.11e-205 569.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,3F40W@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family - - - - - - - - - - - - DegV GHFFDFOM_00328 220668.lp_1795 1.97e-87 258.0 COG1846@1|root,COG1846@2|Bacteria,1VCKC@1239|Firmicutes,4HPTV@91061|Bacilli,3F7BA@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_27,MarR,MarR_2 GHFFDFOM_00329 220668.lp_1793 0.0 1113.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,3F3PS@33958|Lactobacillaceae 91061|Bacilli K Fibronectin-binding protein FbpA - - - - - - - - - - - DUF814,FbpA GHFFDFOM_00330 220668.lp_1792 1.6e-171 479.0 COG1277@1|root,COG1277@2|Bacteria,1V1GX@1239|Firmicutes,4HG2P@91061|Bacilli,3F52P@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_4 GHFFDFOM_00331 220668.lp_1791 5.3e-209 578.0 COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,3F3YW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_00332 220668.lp_1790 1.37e-119 341.0 COG1051@1|root,COG1051@2|Bacteria,1VDM3@1239|Firmicutes,4HMI0@91061|Bacilli,3F6RN@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX GHFFDFOM_00333 220668.lp_1789 1.19e-176 491.0 COG3860@1|root,COG3860@2|Bacteria,1TPHH@1239|Firmicutes,4HCHE@91061|Bacilli,3F56B@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2087) - - - - - - - - - - - - DUF2087,GerE GHFFDFOM_00334 220668.lp_1788 3.46e-91 266.0 COG3860@1|root,COG3860@2|Bacteria,1V6T5@1239|Firmicutes,4HPJA@91061|Bacilli,3F6JC@33958|Lactobacillaceae 91061|Bacilli S LuxR family transcriptional regulator - - - - - - - - - - - - DUF2087,GIY-YIG GHFFDFOM_00335 220668.lp_1787 1.92e-168 469.0 COG4845@1|root,COG4845@2|Bacteria,1UY81@1239|Firmicutes,4HF75@91061|Bacilli,3F60A@33958|Lactobacillaceae 91061|Bacilli V Chloramphenicol acetyltransferase cat - 2.3.1.28 ko:K19271 - - - - br01600,ko00000,ko01000,ko01504 - - - CAT GHFFDFOM_00338 220668.lp_1786 1.9e-93 272.0 COG5646@1|root,COG5646@2|Bacteria,1V6QT@1239|Firmicutes,4HIUI@91061|Bacilli,3F79K@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DU1801) frataxin - - ko:K05937 - - - - ko00000 - - - DUF1801 GHFFDFOM_00339 220668.lp_1785 2.01e-145 409.0 COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli,3F4JB@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 GHFFDFOM_00340 220668.lp_1784 0.0 1657.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3 GHFFDFOM_00341 220668.lp_1783 1.71e-263 721.0 COG0505@1|root,COG0505@2|Bacteria,1VTN5@1239|Firmicutes,4HT8S@91061|Bacilli,3FC4C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the CarA family carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase GHFFDFOM_00342 220668.lp_1782 1.9e-115 331.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,3F4SR@33958|Lactobacillaceae 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran GHFFDFOM_00343 220668.lp_1781 9.72e-225 619.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,3F3P6@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 GHFFDFOM_00344 220668.lp_1780 1.65e-97 284.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,3F66R@33958|Lactobacillaceae 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 GHFFDFOM_00345 220668.lp_1779 0.0 1090.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,3F3U6@33958|Lactobacillaceae 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS GHFFDFOM_00346 220668.lp_1778 5.04e-82 243.0 2BZWG@1|root,2ZPAS@2|Bacteria,1W31C@1239|Firmicutes,4I09H@91061|Bacilli,3F6SQ@33958|Lactobacillaceae 91061|Bacilli S Family of unknown function (DUF5322) esbA - - - - - - - - - - - DUF5322 GHFFDFOM_00347 220668.lp_1777 1.34e-86 254.0 COG0328@1|root,COG0328@2|Bacteria,1VH2B@1239|Firmicutes,4HIY9@91061|Bacilli,3F7JC@33958|Lactobacillaceae 91061|Bacilli L Ribonuclease HI rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H,RVT_3 GHFFDFOM_00348 220668.lp_1776 2.44e-267 731.0 COG0665@1|root,COG0665@2|Bacteria,1TQTF@1239|Firmicutes,4HA0F@91061|Bacilli,3F410@33958|Lactobacillaceae 91061|Bacilli E FAD dependent oxidoreductase yurR - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO GHFFDFOM_00349 220668.lp_1774 1.06e-186 519.0 COG0596@1|root,COG0596@2|Bacteria 2|Bacteria S hydrolase activity, acting on ester bonds - - - - - - - - - - - - Abhydrolase_6 GHFFDFOM_00350 220668.lp_1773 1.86e-246 678.0 2BKEI@1|root,32EV9@2|Bacteria,1U5GV@1239|Firmicutes,4IF7K@91061|Bacilli,3F5WP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00351 220668.lp_1771 1.9e-156 439.0 COG1121@1|root,COG1121@2|Bacteria,1U52X@1239|Firmicutes,4IEUB@91061|Bacilli,3F47U@33958|Lactobacillaceae 91061|Bacilli P ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_00352 220668.lp_1770 3.3e-158 446.0 2BQSR@1|root,32JPE@2|Bacteria,1U52G@1239|Firmicutes,4IETW@91061|Bacilli,3F46K@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - GHFFDFOM_00353 220668.lp_1768 1.68e-233 643.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HDUZ@91061|Bacilli,3F3NK@33958|Lactobacillaceae 91061|Bacilli V LD-carboxypeptidase - - - - - - - - - - - - Peptidase_S66 GHFFDFOM_00354 220668.lp_1767 9.68e-309 843.0 COG3757@1|root,COG3757@2|Bacteria,1V2YH@1239|Firmicutes,4HKBF@91061|Bacilli,3F4G3@33958|Lactobacillaceae 91061|Bacilli M hydrolase, family 25 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25 GHFFDFOM_00355 60520.HR47_12515 1.66e-101 295.0 COG0454@1|root,COG0454@2|Bacteria,1UI4U@1239|Firmicutes,4ISEZ@91061|Bacilli,3FBSP@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - - GHFFDFOM_00356 220668.lp_1764 3.46e-267 730.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HDUZ@91061|Bacilli,3F3NK@33958|Lactobacillaceae 91061|Bacilli V LD-carboxypeptidase mccF - - - - - - - - - - - Peptidase_S66 GHFFDFOM_00357 220668.lp_1763 6.78e-307 837.0 COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,4HVYS@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glycos_transf_2 GHFFDFOM_00358 220668.lp_1762 7.86e-96 278.0 COG3631@1|root,COG3631@2|Bacteria,1V76Z@1239|Firmicutes,4HP66@91061|Bacilli,3F8AB@33958|Lactobacillaceae 91061|Bacilli S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 GHFFDFOM_00359 220668.lp_1760 4.17e-186 516.0 COG1073@1|root,COG1073@2|Bacteria,1TTC0@1239|Firmicutes,4HBCG@91061|Bacilli,3F5IB@33958|Lactobacillaceae 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily yitV - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4,Peptidase_S9 GHFFDFOM_00361 220668.lp_1756 4.8e-281 768.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,3F3NZ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 GHFFDFOM_00363 1136177.KCA1_1523 9.98e-75 223.0 COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli,3F6VZ@33958|Lactobacillaceae 91061|Bacilli D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gpsB - - - - - - - - - - - DivIVA GHFFDFOM_00364 220668.lp_1753 2.12e-142 400.0 COG4474@1|root,COG4474@2|Bacteria,1V6SM@1239|Firmicutes,4HJGM@91061|Bacilli,3F4MR@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0398 family ypsA - - - - - - - - - - - DUF1273 GHFFDFOM_00365 220668.lp_1752 3.6e-152 427.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli,3F4DG@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU GHFFDFOM_00366 220668.lp_1751 0.0 1338.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F424@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein 1A ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 GHFFDFOM_00367 220668.lp_1750 8.37e-231 635.0 COG3842@1|root,COG3842@2|Bacteria,1TPW2@1239|Firmicutes,4HD3J@91061|Bacilli,3F55Y@33958|Lactobacillaceae 91061|Bacilli P ATPases associated with a variety of cellular activities phnT - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 GHFFDFOM_00368 220668.lp_1749 1.15e-233 644.0 COG1840@1|root,COG1840@2|Bacteria,1TQC3@1239|Firmicutes,4HBE1@91061|Bacilli,3F5CD@33958|Lactobacillaceae 91061|Bacilli P Bacterial extracellular solute-binding protein ftpB - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 GHFFDFOM_00369 220668.lp_1748 0.0 1038.0 COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,4HC5I@91061|Bacilli,3F5YV@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component ftpA - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 GHFFDFOM_00370 220668.lp_1747 1.31e-109 316.0 COG0589@1|root,COG0589@2|Bacteria,1U426@1239|Firmicutes,4IF5I@91061|Bacilli,3F5PR@33958|Lactobacillaceae 91061|Bacilli T Universal stress protein family - - - - - - - - - - - - Usp GHFFDFOM_00371 220668.lp_1746 3.19e-203 562.0 COG1464@1|root,COG1464@2|Bacteria,1V0Z6@1239|Firmicutes,4HBBW@91061|Bacilli,3FC6K@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family metQ1 - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 GHFFDFOM_00372 220668.lp_1745 4.05e-141 400.0 COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,4HBEV@91061|Bacilli,3F48A@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 GHFFDFOM_00373 220668.lp_1744 3.97e-172 486.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,3F3U5@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL GHFFDFOM_00374 220668.lp_1744 1.06e-34 127.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,3F3U5@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL GHFFDFOM_00376 220668.lp_1741 1.13e-165 464.0 COG3935@1|root,COG3935@2|Bacteria,1V283@1239|Firmicutes,4HFP3@91061|Bacilli,3FC5X@33958|Lactobacillaceae 91061|Bacilli L Replication initiation and membrane attachment dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2,HTH_36 GHFFDFOM_00377 220668.lp_1740 0.0 892.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,3F4EK@33958|Lactobacillaceae 91061|Bacilli J Asparaginyl-tRNA synthetase asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon GHFFDFOM_00378 220668.lp_1739 3.1e-289 790.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 GHFFDFOM_00379 220668.lp_1738 2.53e-107 310.0 COG5353@1|root,COG5353@2|Bacteria 2|Bacteria S protein conserved in bacteria ypmB - - - - - - - - - - - PepSY GHFFDFOM_00380 220668.lp_1737 0.0 1822.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,3F4KA@33958|Lactobacillaceae 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII GHFFDFOM_00381 220668.lp_1735 1.48e-217 601.0 COG1577@1|root,COG1577@2|Bacteria,1TT5C@1239|Firmicutes,4HAQQ@91061|Bacilli,3F3TW@33958|Lactobacillaceae 91061|Bacilli I mevalonate kinase mvk - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N GHFFDFOM_00382 220668.lp_1734 1.1e-230 635.0 COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli,3F4B5@33958|Lactobacillaceae 91061|Bacilli I diphosphomevalonate decarboxylase mvaD - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N GHFFDFOM_00383 220668.lp_1733 2.41e-260 713.0 COG1577@1|root,COG1577@2|Bacteria,1TPKP@1239|Firmicutes,4HC93@91061|Bacilli,3F3RZ@33958|Lactobacillaceae 91061|Bacilli I phosphomevalonate kinase mvaK2 - 2.7.4.2 ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R03245 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N GHFFDFOM_00384 220668.lp_1732 1.43e-249 685.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,3F3UY@33958|Lactobacillaceae 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh GHFFDFOM_00385 220668.lp_1731 6.77e-247 677.0 COG2017@1|root,COG2017@2|Bacteria,1V5UK@1239|Firmicutes,4HTRY@91061|Bacilli,3FC7G@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of alpha and beta anomers of maltose galM2 - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim GHFFDFOM_00386 220668.lp_1730 0.0 1493.0 COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,3F3PG@33958|Lactobacillaceae 91061|Bacilli G hydrolase, family 65, central catalytic mapA - 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 - R01555 RC00049 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m GHFFDFOM_00387 220668.lp_1729 0.0 870.0 COG2211@1|root,COG2211@2|Bacteria,1TRP7@1239|Firmicutes,4HCUK@91061|Bacilli,3F3YZ@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator malT - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 GHFFDFOM_00388 220668.lp_1726 2.06e-158 449.0 2DR8S@1|root,33AQ2@2|Bacteria,1W05T@1239|Firmicutes,4HZ0I@91061|Bacilli,3F63G@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4767) - - - - - - - - - - - - DUF4767,zinc_ribbon_2 GHFFDFOM_00389 220668.lp_1724 0.0 926.0 COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli,3F492@33958|Lactobacillaceae 91061|Bacilli J NOL1 NOP2 sun family protein rsmF - - - - - - - - - - - Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI GHFFDFOM_00390 220668.lp_1723 2.23e-191 531.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,3F47B@33958|Lactobacillaceae 91061|Bacilli S hydrolase yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 GHFFDFOM_00391 220668.lp_1722 0.0 923.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F3QY@33958|Lactobacillaceae 91061|Bacilli E Amino Acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 GHFFDFOM_00392 220668.lp_1721 0.0 898.0 COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,4H9M7@91061|Bacilli,3F569@33958|Lactobacillaceae 91061|Bacilli E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gabT - 2.6.1.19,5.1.1.21 ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 GHFFDFOM_00393 220668.lp_1718 3.23e-58 180.0 29QP8@1|root,30BNW@2|Bacteria,1U8DV@1239|Firmicutes,4IIBS@91061|Bacilli,3FAVI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00394 220668.lp_1717 1.25e-66 202.0 2CH92@1|root,30ANJ@2|Bacteria,1U6WR@1239|Firmicutes,4IGQX@91061|Bacilli,3F8MV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00395 220668.lp_1716 5.03e-182 506.0 COG1340@1|root,COG1340@2|Bacteria,1UI61@1239|Firmicutes,4ISEY@91061|Bacilli,3FBSN@33958|Lactobacillaceae 91061|Bacilli U Ion channel - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2 GHFFDFOM_00396 220668.lp_1715 1.04e-218 603.0 COG1575@1|root,COG1575@2|Bacteria,1VW8B@1239|Firmicutes,4HW7F@91061|Bacilli,3F50H@33958|Lactobacillaceae 91061|Bacilli H UbiA prenyltransferase family - - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA GHFFDFOM_00397 220668.lp_1713 0.0 882.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,3F3VJ@33958|Lactobacillaceae 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC GHFFDFOM_00398 1136177.KCA1_1460 8.39e-38 126.0 COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli,3F83T@33958|Lactobacillaceae 91061|Bacilli G Belongs to the 4-oxalocrotonate tautomerase family dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase GHFFDFOM_00399 220668.lp_1711 0.0 973.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD4 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 GHFFDFOM_00400 220668.lp_1709 1.06e-53 168.0 2CH91@1|root,30AAP@2|Bacteria,1U6EF@1239|Firmicutes,4IG67@91061|Bacilli,3F7QH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00401 220668.lp_1708 4e-40 133.0 COG3237@1|root,COG3237@2|Bacteria,1VZVB@1239|Firmicutes,4HYP0@91061|Bacilli,3F7E6@33958|Lactobacillaceae 91061|Bacilli S CsbD-like - - - - - - - - - - - - CsbD GHFFDFOM_00402 220668.lp_1706 2.22e-55 172.0 COG2261@1|root,COG2261@2|Bacteria,1U6BD@1239|Firmicutes,4IG2Z@91061|Bacilli,3F7IA@33958|Lactobacillaceae 91061|Bacilli S transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc GHFFDFOM_00403 220668.lp_1705 5.79e-21 82.4 2BHKH@1|root,32BP3@2|Bacteria,1U78C@1239|Firmicutes,4IH38@91061|Bacilli,3F93Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00404 220668.lp_1704 1.51e-48 155.0 2BU5G@1|root,32PEE@2|Bacteria,1U6P5@1239|Firmicutes,4IGG5@91061|Bacilli,3F88H@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00405 220668.lp_1703 1.47e-210 582.0 COG1597@1|root,COG1597@2|Bacteria,1V4PN@1239|Firmicutes,4HHJP@91061|Bacilli,3F3Z6@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat GHFFDFOM_00406 220668.lp_1702 3.92e-87 255.0 COG3152@1|root,COG3152@2|Bacteria,1V90R@1239|Firmicutes,4HWPI@91061|Bacilli,3F6JH@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 GHFFDFOM_00407 220668.lp_1701 5.28e-100 290.0 COG0589@1|root,COG0589@2|Bacteria,1U425@1239|Firmicutes,4I3ZI@91061|Bacilli,3F6XU@33958|Lactobacillaceae 91061|Bacilli T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp GHFFDFOM_00408 220668.lp_1700 6.05e-108 311.0 COG3476@1|root,COG3476@2|Bacteria,1V896@1239|Firmicutes,4HK1B@91061|Bacilli,3F6ED@33958|Lactobacillaceae 91061|Bacilli T TspO/MBR family tspO - - ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 - - - ko00000,ko00001,ko02000 9.A.24 - - TspO_MBR GHFFDFOM_00409 220668.lp_1699 2.05e-55 172.0 2CH90@1|root,2ZP4M@2|Bacteria,1W1QU@1239|Firmicutes,4I01G@91061|Bacilli,3F71E@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00410 220668.lp_1698 1.57e-64 196.0 COG1359@1|root,COG1359@2|Bacteria,1VG4T@1239|Firmicutes,4HPNQ@91061|Bacilli,3F7H6@33958|Lactobacillaceae 91061|Bacilli S Antibiotic biosynthesis monooxygenase ycnE GO:0003674,GO:0003824 - - - - - - - - - - ABM GHFFDFOM_00411 220668.lp_1697 9.96e-147 412.0 COG3397@1|root,COG3397@2|Bacteria,1V9FX@1239|Firmicutes,4HK49@91061|Bacilli,3F5UI@33958|Lactobacillaceae 91061|Bacilli S Lytic polysaccharide mono-oxygenase, cellulose-degrading - - 1.14.99.53 ko:K21713 - - - - ko00000,ko01000 - AA10 - LPMO_10 GHFFDFOM_00412 220668.lp_1696 4.83e-276 755.0 COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,4HDKI@91061|Bacilli,3F3PA@33958|Lactobacillaceae 91061|Bacilli M cyclopropane-fatty-acyl-phospholipid synthase cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS GHFFDFOM_00413 220668.lp_3575 6.98e-63 196.0 COG3275@1|root,COG3275@2|Bacteria,1VB87@1239|Firmicutes,4ISET@91061|Bacilli,3FBSH@33958|Lactobacillaceae 91061|Bacilli T ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt GHFFDFOM_00414 1229758.C270_04340 1.76e-15 68.9 292I6@1|root,2ZQ2A@2|Bacteria,1W25C@1239|Firmicutes,4I09I@91061|Bacilli,4AYA1@81850|Leuconostocaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00415 220668.lp_3577 1.96e-21 86.7 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein ytgB - - - - - - - - - - - Transgly_assoc GHFFDFOM_00416 220668.lp_3578 0.0 1003.0 COG0753@1|root,COG0753@2|Bacteria,1TPPV@1239|Firmicutes,4H9XQ@91061|Bacilli,3F5CW@33958|Lactobacillaceae 91061|Bacilli C Belongs to the catalase family katA GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel GHFFDFOM_00417 220668.lp_3579 1.32e-101 294.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F9GQ@33958|Lactobacillaceae 91061|Bacilli K ArsC family nrp - - ko:K16509 - - - - ko00000 - - - ArsC GHFFDFOM_00418 220668.lp_3580 1.75e-172 481.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,3F9BM@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg GHFFDFOM_00419 60520.HR47_10820 3.78e-212 596.0 COG3290@1|root,COG3290@2|Bacteria,1V1ET@1239|Firmicutes,4HGNA@91061|Bacilli,3F71I@33958|Lactobacillaceae 91061|Bacilli T GHKL domain blpH - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 GHFFDFOM_00420 60520.HR47_10815 9.62e-19 77.0 2BU7S@1|root,32PH8@2|Bacteria,1U8H3@1239|Firmicutes,4IIEY@91061|Bacilli,3FAZ6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00421 60520.HR47_10810 1.51e-85 258.0 COG4512@1|root,COG4512@2|Bacteria,1VKU7@1239|Firmicutes,4IH6Z@91061|Bacilli,3F9AM@33958|Lactobacillaceae 91061|Bacilli KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor - - - ko:K07813 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01002 - - - AgrB GHFFDFOM_00422 220668.lp_3583 0.0 1344.0 COG0542@1|root,COG0542@2|Bacteria,1TRHP@1239|Firmicutes,4HAHZ@91061|Bacilli,3FC3Z@33958|Lactobacillaceae 91061|Bacilli O C-terminal, D2-small domain, of ClpB protein clpL - - ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR GHFFDFOM_00424 220668.lp_3586 1.97e-256 704.0 COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,4HAU5@91061|Bacilli,3F3N3@33958|Lactobacillaceae 91061|Bacilli C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases lctO - 1.13.12.4 ko:K00467,ko:K10530 ko00620,map00620 - R00319 RC01312 ko00000,ko00001,ko01000 - - - FMN_dh GHFFDFOM_00425 220668.lp_3587 0.0 1147.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family pox4 - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GHFFDFOM_00426 220668.lp_3588 5.03e-95 277.0 COG1959@1|root,COG1959@2|Bacteria,1V34F@1239|Firmicutes,4IFKN@91061|Bacilli,3F6N2@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - Rrf2 GHFFDFOM_00427 220668.lp_3589 0.0 1192.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family spxB - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GHFFDFOM_00428 220668.lp_3590 1.65e-93 273.0 COG5506@1|root,COG5506@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1694) yueI - - - - - - - - - - - DUF1694 GHFFDFOM_00429 220668.lp_3591 2.71e-162 456.0 COG2364@1|root,COG2364@2|Bacteria,1VSZX@1239|Firmicutes,4HTJ1@91061|Bacilli,3F4ZU@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - GHFFDFOM_00430 220668.lp_3592 1.31e-210 581.0 COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,4H9QT@91061|Bacilli,3F4WZ@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde rhaD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.2.19 ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01785,R02263 RC00438,RC00599,RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II GHFFDFOM_00431 220668.lp_3593 0.0 882.0 COG4806@1|root,COG4806@2|Bacteria,1TS42@1239|Firmicutes,4HBQP@91061|Bacilli,3F5GK@33958|Lactobacillaceae 91061|Bacilli G L-rhamnose isomerase (RhaA) rhaA GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 2.7.1.5,5.3.1.14 ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01902,R02437,R03014 RC00002,RC00017,RC00434 ko00000,ko00001,ko01000 - - - RhaA GHFFDFOM_00432 220668.lp_3594 4.22e-74 221.0 COG3254@1|root,COG3254@2|Bacteria,1VA1C@1239|Firmicutes,4HM5P@91061|Bacilli,3F70M@33958|Lactobacillaceae 91061|Bacilli G Involved in the anomeric conversion of L-rhamnose rhaM - 5.1.3.32 ko:K03534 - - R10819 RC00563 ko00000,ko01000 - - - rhaM GHFFDFOM_00433 220668.lp_3595 0.0 990.0 COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,4HB5X@91061|Bacilli,3F3UM@33958|Lactobacillaceae 91061|Bacilli F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate rhaB GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 2.7.1.5 ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01902,R03014 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N GHFFDFOM_00434 220668.lp_3596 2.31e-314 857.0 COG0477@1|root,COG2814@2|Bacteria,1TRBM@1239|Firmicutes,4HE7W@91061|Bacilli,3F5E4@33958|Lactobacillaceae 91061|Bacilli P Sugar (and other) transporter iolF GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K06610 - - - - ko00000,ko02000 2.A.1.1.27 - - MFS_1,Sugar_tr GHFFDFOM_00435 220668.lp_3597 3.4e-229 631.0 COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TS6T@1239|Firmicutes,4HGX3@91061|Bacilli,3FBEN@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein rhaR - - - - - - - - - - - AraC_binding,HTH_18 GHFFDFOM_00436 220668.lp_3598 1.28e-180 503.0 COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,4HBKU@91061|Bacilli,3FBHX@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR GHFFDFOM_00437 220668.lp_3599 3.71e-105 303.0 COG1762@1|root,COG1762@2|Bacteria,1VAHC@1239|Firmicutes,4HPPC@91061|Bacilli,3F7U5@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 pts36A - 2.7.1.200 ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_EIIA_2 GHFFDFOM_00438 220668.lp_3600 2.47e-68 206.0 COG3414@1|root,COG3414@2|Bacteria,1VDFN@1239|Firmicutes,4HSG7@91061|Bacilli,3FBN6@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_IIB GHFFDFOM_00439 220668.lp_3601 0.0 936.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HAIT@91061|Bacilli,3FCCE@33958|Lactobacillaceae 91061|Bacilli G PTS system sugar-specific permease component pts36C - - ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 - - EIIC-GAT GHFFDFOM_00441 220668.lp_3603 4.32e-174 485.0 COG0235@1|root,COG0235@2|Bacteria,1V3MT@1239|Firmicutes,4HI2W@91061|Bacilli,3F54X@33958|Lactobacillaceae 91061|Bacilli G Class II Aldolase and Adducin N-terminal domain - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II GHFFDFOM_00442 220668.lp_3604 0.0 905.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,3F3ZS@33958|Lactobacillaceae 91061|Bacilli EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - - - - - - - - - - Sugar_tr GHFFDFOM_00443 220668.lp_3605 4.6e-74 230.0 COG0673@1|root,COG0673@2|Bacteria,1TQJX@1239|Firmicutes,4HAJ8@91061|Bacilli,3F5FQ@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain iolG2 - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C GHFFDFOM_00444 220668.lp_3605 1.19e-135 390.0 COG0673@1|root,COG0673@2|Bacteria,1TQJX@1239|Firmicutes,4HAJ8@91061|Bacilli,3F5FQ@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain iolG2 - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C GHFFDFOM_00445 220668.lp_3606 2.4e-258 707.0 COG0673@1|root,COG0673@2|Bacteria,1TRHA@1239|Firmicutes,4HA6R@91061|Bacilli,3F4K5@33958|Lactobacillaceae 91061|Bacilli C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively iolG - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C GHFFDFOM_00446 220668.lp_3607 3.39e-226 622.0 COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,4HCIM@91061|Bacilli,3F5FP@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) iolE - 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 - - - AP_endonuc_2 GHFFDFOM_00447 220668.lp_3608 6.56e-252 690.0 COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HAKY@91061|Bacilli,3F620@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain idhA - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C GHFFDFOM_00448 220668.lp_3611 0.0 927.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,3F3ZS@33958|Lactobacillaceae 91061|Bacilli EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family iolT GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K06609 - - - - ko00000,ko02000 2.A.1.1.26 - - Sugar_tr GHFFDFOM_00449 220668.lp_3612 1.87e-246 676.0 COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HCS4@91061|Bacilli,3F41H@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249,GO:0055114 1.1.1.18,1.1.1.361,1.1.1.369 ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C GHFFDFOM_00450 220668.lp_3613 7.45e-108 310.0 COG4702@1|root,COG4702@2|Bacteria,1VBQP@1239|Firmicutes,4HKW7@91061|Bacilli,3F780@33958|Lactobacillaceae 91061|Bacilli S Haem-degrading - - - - - - - - - - - - Haem_degrading GHFFDFOM_00451 220668.lp_3614 1.6e-220 608.0 COG0604@1|root,COG0604@2|Bacteria,1V7QI@1239|Firmicutes,4HJMD@91061|Bacilli,3F69N@33958|Lactobacillaceae 91061|Bacilli C Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 GHFFDFOM_00452 220668.lp_3615 1.44e-228 629.0 COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,4HEK7@91061|Bacilli,3FB76@33958|Lactobacillaceae 91061|Bacilli F Inosine-uridine preferring nucleoside hydrolase - - - ko:K01250 - - - - ko00000,ko01000 - - - IU_nuc_hydro GHFFDFOM_00453 220668.lp_3617 2.88e-153 431.0 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,4HA8G@91061|Bacilli,3F4Q8@33958|Lactobacillaceae 91061|Bacilli H Transaldolase/Fructose-6-phosphate aldolase mipB - 2.2.1.2 ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA GHFFDFOM_00454 220668.lp_3618 6.21e-81 240.0 COG3731@1|root,COG3731@2|Bacteria,1VG8V@1239|Firmicutes,4HPTF@91061|Bacilli,3F7KY@33958|Lactobacillaceae 91061|Bacilli G PTS system glucitol/sorbitol-specific IIA component pts38A - 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - PTSIIA_gutA GHFFDFOM_00455 220668.lp_3619 5.39e-228 629.0 COG3732@1|root,COG3732@2|Bacteria,1TQ8F@1239|Firmicutes,4HA7E@91061|Bacilli,3F5AP@33958|Lactobacillaceae 91061|Bacilli G Sorbitol phosphotransferase enzyme II N-terminus srlE - 2.7.1.198 ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - EIIBC-GUT_C,EIIBC-GUT_N GHFFDFOM_00456 220668.lp_3620 1.88e-131 373.0 COG3730@1|root,COG3730@2|Bacteria,1URER@1239|Firmicutes,4HEHX@91061|Bacilli,3F445@33958|Lactobacillaceae 91061|Bacilli G PTS system enzyme II sorbitol-specific factor srlA - - ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.4.1 - - EII-GUT GHFFDFOM_00457 220668.lp_3621 4.71e-119 340.0 COG4578@1|root,COG4578@2|Bacteria,1VHYU@1239|Firmicutes,4HP9S@91061|Bacilli,3F7F5@33958|Lactobacillaceae 91061|Bacilli K Glucitol operon activator protein (GutM) srlM1 - - - - - - - - - - - GutM GHFFDFOM_00458 220668.lp_3622 0.0 1211.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1UZ36@1239|Firmicutes,4HDUK@91061|Bacilli,3F5E0@33958|Lactobacillaceae 91061|Bacilli GKT Mga helix-turn-helix domain srlM - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2 GHFFDFOM_00459 220668.lp_3623 4.26e-185 516.0 COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,4HCAG@91061|Bacilli,3F4CR@33958|Lactobacillaceae 91061|Bacilli IQ NAD dependent epimerase/dehydratase family srlD - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - adh_short GHFFDFOM_00460 220668.lp_3625 9.08e-235 646.0 COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,4HBNT@91061|Bacilli,3F5CG@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LacI family cytR - - ko:K02529,ko:K03604 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 GHFFDFOM_00461 220668.lp_3626 0.0 917.0 COG2211@1|root,COG2211@2|Bacteria,1TRP7@1239|Firmicutes,4HCUK@91061|Bacilli,3F3YZ@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 GHFFDFOM_00462 220668.lp_3627 0.0 1177.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein malL - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,DUF3459,Malt_amylase_C GHFFDFOM_00463 1231377.C426_0083 8.82e-122 377.0 COG1479@1|root,COG1479@2|Bacteria 2|Bacteria U Protein of unknown function DUF262 - - - - - - - - - - - - DUF1524,DUF262 GHFFDFOM_00464 220668.lp_3629 0.0 984.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,3FC7B@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bgl - 3.2.1.21,3.2.1.86 ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 GHFFDFOM_00465 220668.lp_3630 1.4e-205 569.0 COG1940@1|root,COG1940@2|Bacteria,1UZ80@1239|Firmicutes,4HD5J@91061|Bacilli,3FBD4@33958|Lactobacillaceae 91061|Bacilli GK ROK family ypbG - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK GHFFDFOM_00466 220668.lp_3631 0.0 1809.0 COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HBC7@91061|Bacilli,3F4XS@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 38 N-terminal domain - - 2.3.1.204,3.2.1.170,3.2.1.24 ko:K01191,ko:K15524,ko:K16869 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04131 - GH38 - Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C GHFFDFOM_00467 220668.lp_3632 0.0 879.0 COG3538@1|root,COG3538@2|Bacteria,1TRJI@1239|Firmicutes,4HBQW@91061|Bacilli,3F535@33958|Lactobacillaceae 91061|Bacilli S Metal-independent alpha-mannosidase (GH125) - - - ko:K09704 - - - - ko00000 - - - Glyco_hydro_125 GHFFDFOM_00468 220668.lp_3633 1.95e-250 687.0 COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,4HARD@91061|Bacilli,3F3ZM@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - GntR,Peripla_BP_3 GHFFDFOM_00469 220668.lp_3634 0.0 1493.0 COG3537@1|root,COG3537@2|Bacteria,1TQAG@1239|Firmicutes,4HBMP@91061|Bacilli,3F5E5@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolase family 92 ypdD - - - - - - - - - - - Glyco_hydro_92 GHFFDFOM_00470 220668.lp_3635 6.81e-274 749.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,3FC3D@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 GHFFDFOM_00471 220668.lp_3637 3.76e-212 585.0 COG1940@1|root,COG1940@2|Bacteria,1TQU4@1239|Firmicutes,4HA1C@91061|Bacilli,3F3K8@33958|Lactobacillaceae 91061|Bacilli GK ROK family scrK - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK GHFFDFOM_00472 220668.lp_3638 0.0 932.0 COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSN6@1239|Firmicutes,4HC7D@91061|Bacilli,3F5EJ@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - ko:K07720 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_18,Response_reg GHFFDFOM_00473 220668.lp_3639 0.0 1085.0 COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,4HIS6@91061|Bacilli,3FBSJ@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K07718 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase GHFFDFOM_00474 220668.lp_3640 1.71e-139 394.0 COG5578@1|root,COG5578@2|Bacteria,1VE6A@1239|Firmicutes,4HMBU@91061|Bacilli,3F76H@33958|Lactobacillaceae 91061|Bacilli S integral membrane protein ypcB - - - - - - - - - - - DUF624 GHFFDFOM_00475 220668.lp_3641 0.0 1122.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein dexB - 3.2.1.70 ko:K01215 - - - - ko00000,ko01000 - - - Alpha-amylase,DUF3459,Malt_amylase_C GHFFDFOM_00476 220668.lp_3642 0.0 969.0 COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,4HBPS@91061|Bacilli,3F525@33958|Lactobacillaceae 91061|Bacilli G Domain of unknown function (DUF3502) ypcG - - ko:K17318 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - DUF3502,SBP_bac_1,SBP_bac_8 GHFFDFOM_00477 220668.lp_3643 6.47e-213 588.0 COG0395@1|root,COG0395@2|Bacteria,1TP1G@1239|Firmicutes,4HAID@91061|Bacilli,3F5SV@33958|Lactobacillaceae 91061|Bacilli U Binding-protein-dependent transport system inner membrane component lplC - - ko:K17320 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - BPD_transp_1 GHFFDFOM_00478 220668.lp_3644 1.29e-231 637.0 COG4209@1|root,COG4209@2|Bacteria,1TQFY@1239|Firmicutes,4HBB0@91061|Bacilli,3F5UU@33958|Lactobacillaceae 91061|Bacilli U Binding-protein-dependent transport system inner membrane component ypdA - - ko:K17319 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - BPD_transp_1 GHFFDFOM_00479 220668.lp_3645 0.0 1228.0 COG3525@1|root,COG3525@2|Bacteria,1TRN0@1239|Firmicutes,4HCG4@91061|Bacilli,3F42P@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolase family 20, catalytic domain - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - Glyco_hydro_20 GHFFDFOM_00480 220668.lp_3646 9.5e-200 553.0 COG2207@1|root,COG2207@2|Bacteria,1UV2E@1239|Firmicutes,4I2JX@91061|Bacilli,3F665@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,HTH_18 GHFFDFOM_00481 220668.lp_3647 0.0 1133.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlA2 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran GHFFDFOM_00482 220668.lp_3648 0.0 1118.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yknV - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran GHFFDFOM_00483 220668.lp_3649 3.48e-25 103.0 COG1609@1|root,COG1609@2|Bacteria,1UV2F@1239|Firmicutes,4I2WX@91061|Bacilli,3F58N@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - GntR,Peripla_BP_3 GHFFDFOM_00484 220668.lp_3649 4.37e-163 461.0 COG1609@1|root,COG1609@2|Bacteria,1UV2F@1239|Firmicutes,4I2WX@91061|Bacilli,3F58N@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - GntR,Peripla_BP_3 GHFFDFOM_00485 220668.lp_3650 3.7e-199 552.0 COG2508@1|root,COG2508@2|Bacteria,1V649@1239|Firmicutes,4HHCD@91061|Bacilli,3F7G1@33958|Lactobacillaceae 91061|Bacilli QT PucR C-terminal helix-turn-helix domain lrp - - - - - - - - - - - HTH_30 GHFFDFOM_00486 220668.lp_3652 6.96e-83 245.0 COG3731@1|root,COG3731@2|Bacteria,1VG8V@1239|Firmicutes,4HPTF@91061|Bacilli,3F7KY@33958|Lactobacillaceae 91061|Bacilli G PTS system glucitol/sorbitol-specific IIA component pts38A - 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - PTSIIA_gutA GHFFDFOM_00487 220668.lp_3653 7.17e-234 644.0 COG3732@1|root,COG3732@2|Bacteria,1TQ8F@1239|Firmicutes,4HA7E@91061|Bacilli,3F5AP@33958|Lactobacillaceae 91061|Bacilli G Sorbitol phosphotransferase enzyme II N-terminus srlE - 2.7.1.198 ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - EIIBC-GUT_C,EIIBC-GUT_N GHFFDFOM_00488 220668.lp_3654 1.23e-129 368.0 COG3730@1|root,COG3730@2|Bacteria,1URER@1239|Firmicutes,4HEHX@91061|Bacilli,3F445@33958|Lactobacillaceae 91061|Bacilli G PTS system enzyme II sorbitol-specific factor srlA - - ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.4.1 - - EII-GUT GHFFDFOM_00489 220668.lp_3655 3.33e-113 325.0 COG4578@1|root,COG4578@2|Bacteria,1VHYU@1239|Firmicutes,4HP9S@91061|Bacilli,3F7F5@33958|Lactobacillaceae 91061|Bacilli K Glucitol operon activator protein (GutM) srlM1 - - - - - - - - - - - GutM GHFFDFOM_00490 220668.lp_3656 0.0 1194.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1UZ36@1239|Firmicutes,4HDUK@91061|Bacilli,3F5E0@33958|Lactobacillaceae 91061|Bacilli GKT Mga helix-turn-helix domain srlM - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2 GHFFDFOM_00491 220668.lp_3657 2.21e-185 516.0 COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,4HCAG@91061|Bacilli,3F4CR@33958|Lactobacillaceae 91061|Bacilli IQ NAD dependent epimerase/dehydratase family srlD2 - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - adh_short GHFFDFOM_00492 220668.lp_3658 2.53e-209 578.0 COG4975@1|root,COG4975@2|Bacteria,1UBJV@1239|Firmicutes,4HB7E@91061|Bacilli,3FB9E@33958|Lactobacillaceae 91061|Bacilli U ribose uptake protein RbsU rbsU - - ko:K06216 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport GHFFDFOM_00493 220668.lp_3659 4.99e-88 258.0 COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,4HIFW@91061|Bacilli,3F6GA@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose rbsD - 5.4.99.62 ko:K06726 ko02010,map02010 - R08247 RC02247 ko00000,ko00001,ko01000 - - - RbsD_FucU GHFFDFOM_00494 220668.lp_3660 7.82e-210 581.0 COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HA87@91061|Bacilli,3F3S5@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB GHFFDFOM_00495 220668.lp_3661 4.04e-241 662.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli,3FC5C@33958|Lactobacillaceae 91061|Bacilli K helix_turn _helix lactose operon repressor rbsR - - ko:K02529,ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 GHFFDFOM_00498 1302286.BAOT01000074_gene2195 1.35e-70 216.0 COG3293@1|root,COG3293@2|Bacteria,1U67N@1239|Firmicutes,4IFY7@91061|Bacilli,3F79E@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_2 GHFFDFOM_00499 220668.lp_1642 4.23e-09 54.3 2FI7A@1|root,349ZW@2|Bacteria,1W0B2@1239|Firmicutes,4HY9R@91061|Bacilli,3F7DI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - EntA_Immun GHFFDFOM_00500 220668.lp_1640 3.15e-78 233.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,3F6K4@33958|Lactobacillaceae 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 GHFFDFOM_00501 220668.lp_1639 1.57e-179 499.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,3F3NP@33958|Lactobacillaceae 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT GHFFDFOM_00502 220668.lp_1638 2.24e-123 351.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,3F74P@33958|Lactobacillaceae 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM GHFFDFOM_00503 220668.lp_1637 9.99e-53 166.0 COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4HNX0@91061|Bacilli,3F829@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0109 family ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 GHFFDFOM_00504 1136177.KCA1_1400 1.6e-58 181.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 GHFFDFOM_00505 220668.lp_1635 9.38e-301 826.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,3F40R@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB GHFFDFOM_00506 220668.lp_1634 1.46e-77 231.0 COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli,3F7FG@33958|Lactobacillaceae 91061|Bacilli S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - ko:K09787 - - - - ko00000 - - - UPF0122 GHFFDFOM_00507 220668.lp_1633 7.71e-298 821.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,3F3YC@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N GHFFDFOM_00508 220668.lp_1632 0.0 2033.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,3F478@33958|Lactobacillaceae 91061|Bacilli D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge GHFFDFOM_00509 220668.lp_1631 4.49e-167 466.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,3F564@33958|Lactobacillaceae 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm GHFFDFOM_00510 220668.lp_1629 3.33e-47 151.0 COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,3F7F4@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding GHFFDFOM_00511 220668.lp_1628 2.17e-244 672.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli,3F4N9@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis GHFFDFOM_00512 220668.lp_1627 0.0 1305.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,3F3JW@33958|Lactobacillaceae 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge GHFFDFOM_00513 220668.lp_1626 0.0 1081.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,3F3X0@33958|Lactobacillaceae 91061|Bacilli S DAK2 domain fusion protein YloV yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 GHFFDFOM_00514 1136177.KCA1_1390 7.09e-76 227.0 COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,3F72W@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function yloU - - - - - - - - - - - Asp23 GHFFDFOM_00515 1136177.KCA1_1389 1.61e-36 123.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli,3F7ZN@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 GHFFDFOM_00516 220668.lp_1622 2.61e-160 448.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,3F4N8@33958|Lactobacillaceae 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic GHFFDFOM_00517 220668.lp_1621 2.22e-151 426.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,3F4KX@33958|Lactobacillaceae 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim GHFFDFOM_00518 220668.lp_1620 1.21e-209 580.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,3F3XH@33958|Lactobacillaceae 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N GHFFDFOM_00519 220668.lp_1619 0.0 1275.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3F4G6@33958|Lactobacillaceae 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase GHFFDFOM_00520 220668.lp_1618 1.62e-173 484.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,3F4UI@33958|Lactobacillaceae 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 GHFFDFOM_00521 220668.lp_1617 0.0 874.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,3F45F@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB GHFFDFOM_00522 220668.lp_1616 1.01e-222 614.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,3F4N7@33958|Lactobacillaceae 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N GHFFDFOM_00523 220668.lp_1615 0.0 1573.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,3F3N8@33958|Lactobacillaceae 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII GHFFDFOM_00524 220668.lp_1614 5.04e-278 762.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,3F3XX@33958|Lactobacillaceae 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein GHFFDFOM_00525 220668.lp_1613 3.93e-41 135.0 COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,4HNHS@91061|Bacilli,3F81N@33958|Lactobacillaceae 91061|Bacilli K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 GHFFDFOM_00526 220668.lp_1612 6.96e-145 408.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,3F3X9@33958|Lactobacillaceae 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin GHFFDFOM_00527 220668.lp_1611 8.28e-73 218.0 2DKP7@1|root,30A5M@2|Bacteria,1U687@1239|Firmicutes,4IFYY@91061|Bacilli,3F7A9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00528 220668.lp_1610 1.36e-136 388.0 COG1174@1|root,COG1174@2|Bacteria,1TQ5C@1239|Firmicutes,4HAVM@91061|Bacilli,3F51B@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component opuCD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iYO844.BSU33800 BPD_transp_1 GHFFDFOM_00529 220668.lp_1609 3.8e-224 617.0 COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HARV@91061|Bacilli,3F420@33958|Lactobacillaceae 91061|Bacilli M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) opuCC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12835 OpuAC GHFFDFOM_00530 220668.lp_1608 7.11e-135 383.0 COG1174@1|root,COG1174@2|Bacteria,1TSX8@1239|Firmicutes,4HC1D@91061|Bacilli,3F4EM@33958|Lactobacillaceae 91061|Bacilli E ABC transporter permease opuCB - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 GHFFDFOM_00531 220668.lp_1607 4.51e-284 776.0 COG1125@1|root,COG2239@1|root,COG1125@2|Bacteria,COG2239@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,3F55H@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein opuCA - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12845,iYO844.BSU33730 ABC_tran,CBS GHFFDFOM_00532 220668.lp_1605 0.0 1064.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,3F43U@33958|Lactobacillaceae 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N GHFFDFOM_00533 220668.lp_1604 5.28e-100 290.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli,3F71C@33958|Lactobacillaceae 91061|Bacilli K Regulates arginine biosynthesis genes argR2 - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C GHFFDFOM_00534 220668.lp_1603 4.49e-192 533.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,3F45T@33958|Lactobacillaceae 91061|Bacilli J Ribosomal RNA large subunit methyltransferase J rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 GHFFDFOM_00535 220668.lp_1602 5.49e-205 568.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,3F436@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt GHFFDFOM_00536 220668.lp_1601 7.55e-44 142.0 COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,3F81K@33958|Lactobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S GHFFDFOM_00537 220668.lp_1600 8.06e-313 853.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,3F4RE@33958|Lactobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 GHFFDFOM_00538 220668.lp_1599 4.82e-194 539.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,3F46A@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C GHFFDFOM_00539 220668.lp_1598 7.76e-89 261.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,3F7KW@33958|Lactobacillaceae 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB GHFFDFOM_00540 220668.lp_1597 1.7e-96 281.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli,3F71X@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function WQ51_04310 - - ko:K10947 - - - - ko00000,ko03000 - - - Asp23 GHFFDFOM_00541 220668.lp_1596 1.43e-129 368.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,3F422@33958|Lactobacillaceae 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C GHFFDFOM_00542 220668.lp_1595 8.58e-249 683.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,3F4DR@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 GHFFDFOM_00543 1136177.KCA1_1359 2.33e-61 188.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli,3F6WU@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 GHFFDFOM_00544 220668.lp_1593 7.97e-71 213.0 COG2868@1|root,COG2868@2|Bacteria,1VEQ9@1239|Firmicutes,4HNMV@91061|Bacilli,3F839@33958|Lactobacillaceae 91061|Bacilli J Cysteine protease Prp ysxB - - ko:K07584 - - - - ko00000 - - - Peptidase_Prp GHFFDFOM_00545 220668.lp_1592 1.55e-66 202.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,3F6WT@33958|Lactobacillaceae 91061|Bacilli J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p GHFFDFOM_00546 220668.lp_1591 4.04e-125 358.0 COG1309@1|root,COG1309@2|Bacteria,1VGVA@1239|Firmicutes,4HPAG@91061|Bacilli,3F3TB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_C_8,TetR_N GHFFDFOM_00547 1136177.KCA1_1355 9.81e-27 97.8 29PZD@1|root,30AXT@2|Bacteria,1U78R@1239|Firmicutes,4IH3M@91061|Bacilli,3F94K@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00550 220668.lp_1587 1.21e-40 134.0 2BRWZ@1|root,32KX8@2|Bacteria,1U6MJ@1239|Firmicutes,4IGED@91061|Bacilli,3F85G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00551 220668.lp_1586 8.92e-73 218.0 2C5TQ@1|root,30A24@2|Bacteria,1U638@1239|Firmicutes,4IFSJ@91061|Bacilli,3F6XK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00552 220668.lp_1585 2.92e-126 359.0 COG4508@1|root,COG4508@2|Bacteria,1VGAY@1239|Firmicutes,4HPDT@91061|Bacilli,3F6E4@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria - - - - - - - - - - - - dUTPase_2 GHFFDFOM_00553 220668.lp_1584 1.34e-232 639.0 2F367@1|root,33W0S@2|Bacteria,1VK1W@1239|Firmicutes,4HWH4@91061|Bacilli,3F3MT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00554 220668.lp_1583 5.08e-205 568.0 2AZ1J@1|root,31R7P@2|Bacteria,1V8SY@1239|Firmicutes,4HJRD@91061|Bacilli,3F4MX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00555 220668.lp_1581 0.0 913.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,3F41A@33958|Lactobacillaceae 91061|Bacilli E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N GHFFDFOM_00556 220668.lp_1580 7.79e-85 250.0 COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli,3F7RX@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - MerR_1 GHFFDFOM_00557 220668.lp_1579 1.33e-224 619.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,3F3XS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT GHFFDFOM_00558 220668.lp_1578 1.1e-178 497.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,3F4CS@33958|Lactobacillaceae 91061|Bacilli C phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD GHFFDFOM_00559 220668.lp_1577 1.44e-31 110.0 2C91M@1|root,33E1E@2|Bacteria,1VPEZ@1239|Firmicutes,4HRR2@91061|Bacilli,3F8C0@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3042) WQ51_02665 - - - - - - - - - - - DUF3042 GHFFDFOM_00560 220668.lp_1576 6.68e-89 261.0 COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,3F67E@33958|Lactobacillaceae 91061|Bacilli P Rhodanese-like protein yqhL - - - - - - - - - - - Rhodanese GHFFDFOM_00561 220668.lp_1574 1.62e-141 400.0 COG3340@1|root,COG3340@2|Bacteria,1V6ZV@1239|Firmicutes,4HJCZ@91061|Bacilli,3F6J6@33958|Lactobacillaceae 91061|Bacilli E Belongs to the peptidase S51 family pepE - 3.4.13.21 ko:K05995 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S51 GHFFDFOM_00562 220668.lp_1573 2.6e-231 636.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,3F4F0@33958|Lactobacillaceae 91061|Bacilli G Glucokinase glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07790 ROK GHFFDFOM_00563 220668.lp_1572 6.33e-46 147.0 COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli,3F83I@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF910) yqgQ - - - - - - - - - - - DUF910 GHFFDFOM_00564 220668.lp_1571 3.52e-153 431.0 COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,3F3WR@33958|Lactobacillaceae 91061|Bacilli S Peptidase, S54 family gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 GHFFDFOM_00565 220668.lp_1570 9.29e-132 374.0 COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,3F4KQ@33958|Lactobacillaceae 91061|Bacilli H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family fthC GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig GHFFDFOM_00566 1136177.KCA1_1336 5.33e-30 105.0 COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,4HNIM@91061|Bacilli,3F828@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 GHFFDFOM_00567 220668.lp_1568 0.0 1262.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,3F3KH@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbp2b - - ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase GHFFDFOM_00568 220668.lp_1567 0.0 1732.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HBW6@91061|Bacilli,3F49G@33958|Lactobacillaceae 91061|Bacilli S membrane - - - - - - - - - - - - YfhO GHFFDFOM_00569 220668.lp_1566 6.12e-72 215.0 COG4841@1|root,COG4841@2|Bacteria,1VEQE@1239|Firmicutes,4HNU2@91061|Bacilli,3F7SB@33958|Lactobacillaceae 91061|Bacilli S Belongs to the HesB IscA family yneR - - - - - - - - - - - Fe-S_biosyn GHFFDFOM_00570 220668.lp_1565 1.35e-97 284.0 COG3279@1|root,COG3279@2|Bacteria,1VEPW@1239|Firmicutes,4HP5K@91061|Bacilli,3FBDY@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR GHFFDFOM_00571 220668.lp_1564 3.96e-145 412.0 COG4758@1|root,COG4758@2|Bacteria,1V7WJ@1239|Firmicutes,4HR21@91061|Bacilli,3F6JJ@33958|Lactobacillaceae 91061|Bacilli S membrane - - - - - - - - - - - - DUF2154 GHFFDFOM_00572 220668.lp_1563 1.09e-105 305.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,3F4ZF@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N GHFFDFOM_00573 220668.lp_1562 7.5e-146 411.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli,3F3KE@33958|Lactobacillaceae 91061|Bacilli F Cytidine monophosphokinase udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK GHFFDFOM_00574 220668.lp_1561 6.11e-249 687.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,3F4IG@33958|Lactobacillaceae 91061|Bacilli S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG GHFFDFOM_00575 220668.lp_1559 0.0 1588.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,3F3V3@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind GHFFDFOM_00576 220668.lp_1558 6.88e-257 703.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,3F4NT@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d GHFFDFOM_00577 1136177.KCA1_1325 1.09e-83 246.0 COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,3F7FK@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, HxlR family yodB GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HxlR GHFFDFOM_00578 220668.lp_1556 1.72e-120 343.0 COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,4HHW0@91061|Bacilli,3F64N@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. XK27_09705 - - ko:K06950 - - - - ko00000 - - - HD GHFFDFOM_00579 220668.lp_1555 2.12e-177 494.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli,3F3NF@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind GHFFDFOM_00580 1136177.KCA1_1322 2.36e-60 185.0 COG1254@1|root,COG1254@2|Bacteria 2|Bacteria C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Acylphosphatase GHFFDFOM_00581 220668.lp_1553 1.4e-208 578.0 COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli,3F3P3@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP GHFFDFOM_00582 220668.lp_1552 1.77e-122 350.0 COG5658@1|root,COG5658@2|Bacteria,1U6DD@1239|Firmicutes,4IG54@91061|Bacilli,3F7NE@33958|Lactobacillaceae 91061|Bacilli S SdpI/YhfL protein family - - - - - - - - - - - - SdpI GHFFDFOM_00583 220668.lp_1549 5.55e-288 786.0 COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,4HAKB@91061|Bacilli,3F4A9@33958|Lactobacillaceae 91061|Bacilli L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C GHFFDFOM_00584 220668.lp_1548 0.0 1826.0 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli,3F3TE@33958|Lactobacillaceae 91061|Bacilli L Putative exonuclease SbcCD, C subunit sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C GHFFDFOM_00585 220668.lp_1546 1.59e-217 602.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F3JM@33958|Lactobacillaceae 91061|Bacilli H 1,4-dihydroxy-2-naphthoate ubiA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA GHFFDFOM_00586 220668.lp_1545 0.0 1051.0 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,3F3NU@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA GHFFDFOM_00587 1136177.KCA1_1314 1.38e-155 437.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,3F421@33958|Lactobacillaceae 91061|Bacilli K response regulator csrR - - - - - - - - - - - Response_reg,Trans_reg_C GHFFDFOM_00589 220668.lp_3352 4.58e-103 298.0 COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HPDH@91061|Bacilli,3F4EY@33958|Lactobacillaceae 91061|Bacilli O Belongs to the small heat shock protein (HSP20) family hsp3 - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 GHFFDFOM_00590 220668.lp_3353 2.27e-74 223.0 2A4XX@1|root,30TJQ@2|Bacteria,1U684@1239|Firmicutes,4IFYV@91061|Bacilli,3F7A6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00591 1136177.KCA1_2738 4.79e-21 83.2 29PWB@1|root,30AUN@2|Bacteria,1U74I@1239|Firmicutes,4IGZ5@91061|Bacilli,3F8YT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00592 220668.lp_3355 3.57e-150 422.0 COG0702@1|root,COG0702@2|Bacteria,1UJSC@1239|Firmicutes,4HCVT@91061|Bacilli,3F4ZZ@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 GHFFDFOM_00593 220668.lp_3356 2.52e-107 309.0 COG2153@1|root,COG2153@2|Bacteria,1VAJY@1239|Firmicutes,4HIH7@91061|Bacilli,3F5B8@33958|Lactobacillaceae 91061|Bacilli S GNAT family - - - ko:K02348 - - - - ko00000 - - - Acetyltransf_10 GHFFDFOM_00594 220668.lp_3358 1.63e-203 565.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F423@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA GHFFDFOM_00595 220668.lp_3359 2.66e-155 437.0 COG1814@1|root,COG1814@2|Bacteria,1V26W@1239|Firmicutes,4HGMW@91061|Bacilli,3F3TU@33958|Lactobacillaceae 91061|Bacilli S membrane - - - - - - - - - - - - VIT1 GHFFDFOM_00596 220668.lp_3360 2.55e-145 411.0 COG1814@1|root,COG1814@2|Bacteria,1V3A2@1239|Firmicutes,4HFSI@91061|Bacilli,3F53V@33958|Lactobacillaceae 91061|Bacilli S VIT family - - - - - - - - - - - - VIT1 GHFFDFOM_00597 220668.lp_3362 4.38e-243 667.0 COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,4HMSI@91061|Bacilli,3FB8X@33958|Lactobacillaceae 91061|Bacilli M Linear amide C-N hydrolases, choloylglycine hydrolase family pva2 - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH GHFFDFOM_00598 220668.lp_3363 0.0 1268.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,3F4IX@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase copB - 3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54 ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5,3.A.3.6 - - E1-E2_ATPase,Hydrolase GHFFDFOM_00599 220668.lp_3365 8.01e-97 281.0 COG3682@1|root,COG3682@2|Bacteria,1VA7Q@1239|Firmicutes,4HKGF@91061|Bacilli,3F7D0@33958|Lactobacillaceae 91061|Bacilli K Copper transport repressor CopY TcrY copR - - ko:K02171 ko01501,map01501 M00627 - - ko00000,ko00001,ko00002,ko01504,ko03000 - - - Penicillinase_R GHFFDFOM_00600 220668.lp_3366 4.26e-54 169.0 29PEA@1|root,30ACG@2|Bacteria,1U6GI@1239|Firmicutes,4IG8Q@91061|Bacilli,3F7VJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00601 220668.lp_3367 3.43e-96 280.0 COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,4HNMT@91061|Bacilli,3F68X@33958|Lactobacillaceae 91061|Bacilli S COG NOG18757 non supervised orthologous group - - - - - - - - - - - - - GHFFDFOM_00602 60520.HR47_01240 1.77e-314 860.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily lmrB - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 GHFFDFOM_00603 220668.lp_3371 7.21e-35 119.0 29PXN@1|root,30AW1@2|Bacteria,1U76D@1239|Firmicutes,4IH14@91061|Bacilli,3F917@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00604 220668.lp_3372 2.55e-65 198.0 29P6Y@1|root,30A51@2|Bacteria,1U67G@1239|Firmicutes,4IFXZ@91061|Bacilli,3F790@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00605 220668.lp_3373 8.4e-85 250.0 COG5562@1|root,COG5562@2|Bacteria,1U5TC@1239|Firmicutes,4IFH9@91061|Bacilli,3F6GH@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1398) - - - - - - - - - - - - DUF1398 GHFFDFOM_00606 220668.lp_3374 0.0 878.0 COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,4HA3B@91061|Bacilli,3F4YG@33958|Lactobacillaceae 91061|Bacilli U Belongs to the purine-cytosine permease (2.A.39) family - - - - - - - - - - - - Transp_cyt_pur GHFFDFOM_00607 220668.lp_3392 2.52e-282 773.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,3F3T5@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein mdtG - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,MFS_1_like,Sugar_tr GHFFDFOM_00608 220668.lp_3393 5.99e-231 635.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta ybcH - - ko:K06889 - - - - ko00000 - - - DLH,FSH1,Hydrolase_4 GHFFDFOM_00609 220668.lp_3394 6.1e-101 293.0 COG0789@1|root,COG0789@2|Bacteria,1U5VW@1239|Firmicutes,4IFJP@91061|Bacilli,3F6KX@33958|Lactobacillaceae 91061|Bacilli K Domain of unknown function (DUF1836) - - - - - - - - - - - - DUF1836 GHFFDFOM_00610 220668.lp_3397 3.28e-110 317.0 COG3613@1|root,COG3613@2|Bacteria,1V70Q@1239|Firmicutes,4IRXR@91061|Bacilli,3FBQG@33958|Lactobacillaceae 91061|Bacilli F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr GHFFDFOM_00611 220668.lp_3398 0.0 1632.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F588@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus pacL3 - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 GHFFDFOM_00612 220668.lp_3400 0.0 1061.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HC2M@91061|Bacilli,3F45U@33958|Lactobacillaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family yfkN - 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 - R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos GHFFDFOM_00613 220668.lp_3402 2.8e-205 570.0 COG0679@1|root,COG0679@2|Bacteria,1VDS9@1239|Firmicutes,4HQT5@91061|Bacilli,3F5JF@33958|Lactobacillaceae 91061|Bacilli S Membrane transport protein ywkB - - ko:K07088 - - - - ko00000 - - - Mem_trans GHFFDFOM_00614 220668.lp_3403 1.36e-209 578.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,3F3PW@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase yvgN - - - - - - - - - - - Aldo_ket_red GHFFDFOM_00615 220668.lp_3404 4.97e-169 473.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,3F4XE@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE GHFFDFOM_00616 220668.lp_3405 2.93e-102 296.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,3F63I@33958|Lactobacillaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 GHFFDFOM_00617 1136177.KCA1_2769 3.68e-57 179.0 28ZBI@1|root,2ZM3D@2|Bacteria,1W5K5@1239|Firmicutes,4I1Q6@91061|Bacilli,3F825@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 GHFFDFOM_00618 220668.lp_3407 5.43e-190 528.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli,3F510@33958|Lactobacillaceae 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA GHFFDFOM_00619 60520.HR47_00205 3.44e-117 335.0 COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,4HIHC@91061|Bacilli,3F6GV@33958|Lactobacillaceae 91061|Bacilli S Macro domain protein ymdB - - - - - - - - - - - Macro GHFFDFOM_00620 220668.lp_3409 6.47e-124 354.0 COG1309@1|root,COG1309@2|Bacteria,1U5JB@1239|Firmicutes,4IFA6@91061|Bacilli,3F62U@33958|Lactobacillaceae 91061|Bacilli K transcriptional regulator - - - ko:K22041 - - - - ko00000,ko03000 - - - TetR_N GHFFDFOM_00621 220668.lp_3410 1.58e-66 202.0 2DZIG@1|root,32VBI@2|Bacteria,1VIUB@1239|Firmicutes,4HRZP@91061|Bacilli,3F7EN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF4870 GHFFDFOM_00622 220668.lp_3411 1.39e-211 587.0 COG4086@1|root,COG4086@2|Bacteria,1UY79@1239|Firmicutes,4HAZ5@91061|Bacilli,3F416@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1002) - - - - - - - - - - - - DUF1002 GHFFDFOM_00623 220668.lp_3412 0.0 1963.0 29PV7@1|root,30ATD@2|Bacteria,1U730@1239|Firmicutes,4IGXI@91061|Bacilli,3F8WR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - WxL GHFFDFOM_00624 220668.lp_3413 1.36e-245 674.0 COG4072@1|root,COG4072@2|Bacteria,1U7FS@1239|Firmicutes,4IHBT@91061|Bacilli,3F9JU@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF916) - - - - - - - - - - - - DUF3324,DUF916 GHFFDFOM_00625 220668.lp_3414 5.48e-171 479.0 29Q22@1|root,30B0N@2|Bacteria,1U7CM@1239|Firmicutes,4IH81@91061|Bacilli,3F9D0@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL GHFFDFOM_00626 220668.lp_3415 1.63e-176 491.0 COG2207@1|root,COG2207@2|Bacteria,1TSKR@1239|Firmicutes,4H9R5@91061|Bacilli 91061|Bacilli T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain yesN - - ko:K07720 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_18,HTH_AraC,Response_reg GHFFDFOM_00627 220668.lp_3416 1.31e-114 328.0 COG1846@1|root,COG1846@2|Bacteria,1U5DI@1239|Firmicutes,4IF50@91061|Bacilli,3F5NB@33958|Lactobacillaceae 91061|Bacilli K Winged helix DNA-binding domain - - - - - - - - - - - - HTH_27 GHFFDFOM_00628 220668.lp_3417 3.81e-150 423.0 COG1309@1|root,COG1309@2|Bacteria,1VZKY@1239|Firmicutes,4HM1C@91061|Bacilli,3F43G@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GHFFDFOM_00629 220668.lp_3418 0.0 1122.0 COG1866@1|root,COG1866@2|Bacteria,1TPXB@1239|Firmicutes,4IS6N@91061|Bacilli,3F4N4@33958|Lactobacillaceae 91061|Bacilli H Phosphoenolpyruvate carboxykinase pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP GHFFDFOM_00630 220668.lp_3419 4.45e-38 127.0 29A0B@1|root,2ZX1X@2|Bacteria,1W51D@1239|Firmicutes,4I0QW@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00631 220668.lp_3420 0.0 983.0 COG0076@1|root,COG0076@2|Bacteria,1TPVX@1239|Firmicutes,4HENF@91061|Bacilli,3F45J@33958|Lactobacillaceae 91061|Bacilli E Belongs to the group II decarboxylase family gadB - 4.1.1.15,4.1.2.27 ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 M00027,M00100 R00261,R00489,R01682,R02464,R02466,R06516 RC00264,RC00299,RC00721,RC01266 ko00000,ko00001,ko00002,ko01000 - - - Pyridoxal_deC GHFFDFOM_00632 220668.lp_3421 2.04e-107 326.0 COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1VFKC@1239|Firmicutes,4IFHN@91061|Bacilli,3F6HG@33958|Lactobacillaceae 91061|Bacilli M PFAM NLP P60 protein - - - - - - - - - - - - LysM,NLPC_P60 GHFFDFOM_00633 220668.lp_3422 2.15e-71 215.0 29P87@1|root,30A69@2|Bacteria,1U693@1239|Firmicutes,4IG08@91061|Bacilli,3F7C5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00634 220668.lp_3423 5.77e-81 240.0 2A5X0@1|root,30UP0@2|Bacteria,1U6DW@1239|Firmicutes,4IG5K@91061|Bacilli,3F7P8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00636 220668.lp_3425 5.13e-138 390.0 2APNY@1|root,31ESI@2|Bacteria,1V7JI@1239|Firmicutes,4HVID@91061|Bacilli,3F6EE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - SnoaL_4 GHFFDFOM_00637 220668.lp_3426 1.22e-68 207.0 COG4367@1|root,COG4367@2|Bacteria,1VGC1@1239|Firmicutes,4HQJ6@91061|Bacilli,3F89N@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2316) - - - - - - - - - - - - DUF2316 GHFFDFOM_00638 220668.lp_3427 4.61e-204 566.0 COG2159@1|root,COG2159@2|Bacteria,1UXYD@1239|Firmicutes,4HDAD@91061|Bacilli,3FB98@33958|Lactobacillaceae 91061|Bacilli S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 GHFFDFOM_00639 220668.lp_3429 1.72e-129 368.0 COG1309@1|root,COG1309@2|Bacteria,1U5IB@1239|Firmicutes,4IF91@91061|Bacilli,3F60H@33958|Lactobacillaceae 91061|Bacilli K transcriptional regulator - - - - - - - - - - - - - GHFFDFOM_00640 220668.lp_3430 2.5e-232 639.0 COG2837@1|root,COG2837@2|Bacteria,1UY9Y@1239|Firmicutes,4HACQ@91061|Bacilli,3F45Z@33958|Lactobacillaceae 91061|Bacilli P Peroxidase ywbN GO:0005575,GO:0005576 - ko:K07223,ko:K16301 - - - - ko00000,ko01000,ko02000 2.A.108.2.3 - iYO844.BSU38260 Dyp_perox,TAT_signal GHFFDFOM_00641 220668.lp_3431 5.92e-175 487.0 COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HAR9@91061|Bacilli,3F3R2@33958|Lactobacillaceae 91061|Bacilli H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran GHFFDFOM_00642 220668.lp_3432 7.76e-168 468.0 COG1434@1|root,COG1434@2|Bacteria,1TS1Q@1239|Firmicutes,4I32T@91061|Bacilli,3F62V@33958|Lactobacillaceae 91061|Bacilli S Gram-negative-bacterium-type cell wall biogenesis - - - - - - - - - - - - DUF218 GHFFDFOM_00643 220668.lp_3433 1.77e-235 647.0 COG2755@1|root,COG2755@2|Bacteria,1TSSA@1239|Firmicutes,4IPPG@91061|Bacilli,3FBDC@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 GHFFDFOM_00644 220668.lp_3435 0.0 1178.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4T3@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase GHFFDFOM_00645 220668.lp_3436 8.08e-184 510.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,3F4J6@33958|Lactobacillaceae 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP GHFFDFOM_00646 1423734.JCM14202_2812 5.73e-73 218.0 COG0526@1|root,COG0526@2|Bacteria,1UI60@1239|Firmicutes,4ISEX@91061|Bacilli,3F6Q0@33958|Lactobacillaceae 91061|Bacilli O Thioredoxin-like domain trxA3 - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin GHFFDFOM_00647 1423734.JCM14202_2813 4.82e-55 172.0 COG1937@1|root,COG1937@2|Bacteria,1VFB9@1239|Firmicutes,4HNVQ@91061|Bacilli,3F74Z@33958|Lactobacillaceae 91061|Bacilli S Metal-sensitive transcriptional repressor yrkD - - - - - - - - - - - Trns_repr_metal GHFFDFOM_00648 220668.lp_3440 1.01e-26 99.0 29PE2@1|root,30AC8@2|Bacteria,1U6GC@1239|Firmicutes,4IG8G@91061|Bacilli,3F7V0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00649 220668.lp_3441 4.27e-126 359.0 COG0783@1|root,COG0783@2|Bacteria,1VB1X@1239|Firmicutes,4HMJG@91061|Bacilli,3F4SN@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Dps family dpsB - - - - - - - - - - - Ferritin GHFFDFOM_00650 220668.lp_3442 2.98e-44 143.0 COG2608@1|root,COG2608@2|Bacteria,1VFJ8@1239|Firmicutes,4HNY2@91061|Bacilli,3F830@33958|Lactobacillaceae 91061|Bacilli P Heavy-metal-associated domain copZ - - - - - - - - - - - HMA GHFFDFOM_00651 220668.lp_3444 1.82e-152 429.0 COG0664@1|root,COG0664@2|Bacteria,1V3XW@1239|Firmicutes,4HDG1@91061|Bacilli,3F4YM@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, Crp Fnr family rcfA - - ko:K21562 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding GHFFDFOM_00652 220668.lp_3445 0.0 1295.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,3F4CX@33958|Lactobacillaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N GHFFDFOM_00653 220668.lp_3448 5.23e-107 308.0 COG1670@1|root,COG1670@2|Bacteria,1VCN3@1239|Firmicutes,4HKNF@91061|Bacilli,3F7GP@33958|Lactobacillaceae 91061|Bacilli J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins yoaA - - - - - - - - - - - Acetyltransf_3 GHFFDFOM_00654 220668.lp_3449 0.0 905.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase nox - 1.6.3.4 ko:K17869 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim GHFFDFOM_00655 220668.lp_3450 0.0 1398.0 COG4886@1|root,COG4886@2|Bacteria,1UI5Z@1239|Firmicutes,4ISEW@91061|Bacilli,3F46F@33958|Lactobacillaceae 91061|Bacilli S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - GHFFDFOM_00656 220668.lp_3451 1.83e-235 648.0 COG4072@1|root,COG4072@2|Bacteria,1VCXS@1239|Firmicutes,4HKJG@91061|Bacilli,3F5HA@33958|Lactobacillaceae 91061|Bacilli S Cell surface protein - - - - - - - - - - - - DUF3324,DUF916 GHFFDFOM_00657 220668.lp_3452 2.48e-159 447.0 29WH0@1|root,30I33@2|Bacteria,1U57C@1239|Firmicutes,4IEYT@91061|Bacilli,3F511@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL GHFFDFOM_00658 220668.lp_3453 4.23e-129 367.0 2BV09@1|root,32QCV@2|Bacteria,1U6PS@1239|Firmicutes,4IGGR@91061|Bacilli,3F89M@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL GHFFDFOM_00659 220668.lp_3454 7.83e-60 184.0 29PBC@1|root,30A9J@2|Bacteria,1U6D2@1239|Firmicutes,4IG4U@91061|Bacilli,3F7N0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00660 220668.lp_3458 7.01e-135 382.0 COG1309@1|root,COG1309@2|Bacteria,1US3R@1239|Firmicutes,4HCGK@91061|Bacilli,3F53A@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family yezE - - ko:K16137 - - - - ko00000,ko03000 - - - TetR_N GHFFDFOM_00661 220668.lp_3459 1.03e-65 199.0 2DDHT@1|root,2ZI5S@2|Bacteria,1W3TC@1239|Firmicutes,4IFYT@91061|Bacilli,3F7A3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00662 220668.lp_3460 9.34e-317 863.0 COG3864@1|root,COG3864@2|Bacteria,1VE6N@1239|Firmicutes,4HMSF@91061|Bacilli,3F556@33958|Lactobacillaceae 91061|Bacilli S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N GHFFDFOM_00663 220668.lp_3461 4.03e-283 774.0 COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,4HCYD@91061|Bacilli,3F53Z@33958|Lactobacillaceae 91061|Bacilli S associated with various cellular activities - - - - - - - - - - - - AAA_5 GHFFDFOM_00664 1136177.KCA1_2814 1.95e-140 398.0 COG0580@1|root,COG0580@2|Bacteria,1UZX3@1239|Firmicutes,4HA8I@91061|Bacilli,3F4K9@33958|Lactobacillaceae 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family aqpZ - - ko:K06188 - - - - ko00000,ko02000 1.A.8 - - MIP GHFFDFOM_00665 220668.lp_3464 0.0 1145.0 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli,3F51C@33958|Lactobacillaceae 91061|Bacilli S ABC1 family ubiB - - ko:K03688 - - - - ko00000 - - - ABC1,APH GHFFDFOM_00685 220668.lp_2230 1.08e-117 336.0 COG2329@1|root,COG2329@2|Bacteria,1V501@1239|Firmicutes,4HHA2@91061|Bacilli,3F3UU@33958|Lactobacillaceae 91061|Bacilli S enzyme involved in biosynthesis of extracellular polysaccharides traP GO:0005575,GO:0016020 1.14.99.57 ko:K21481 - - - - ko00000,ko01000 - - - ABM GHFFDFOM_00686 220668.lp_2229 3.28e-177 493.0 COG1234@1|root,COG1234@2|Bacteria,1V1TF@1239|Firmicutes,4HFNV@91061|Bacilli,3F4U0@33958|Lactobacillaceae 91061|Bacilli S Metallo-beta-lactamase superfamily yhfI GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - - - - - - - - - - Lactamase_B,Lactamase_B_2 GHFFDFOM_00687 220668.lp_2228 9.28e-89 260.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F6HJ@33958|Lactobacillaceae 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC GHFFDFOM_00688 220668.lp_2227 7.12e-170 474.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HID6@91061|Bacilli,3F5G4@33958|Lactobacillaceae 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K16511 - - - - ko00000 - - - MecA GHFFDFOM_00689 220668.lp_2226 4.93e-268 733.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,3F4BZ@33958|Lactobacillaceae 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA GHFFDFOM_00690 220668.lp_2225 0.0 1145.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,3F4E5@33958|Lactobacillaceae 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N GHFFDFOM_00691 220668.lp_2224 2.24e-148 417.0 COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,3F6QR@33958|Lactobacillaceae 91061|Bacilli Q Thioredoxin yjbH - - - - - - - - - - - Thioredoxin_5 GHFFDFOM_00692 220668.lp_2223 9.08e-157 439.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,3F452@33958|Lactobacillaceae 91061|Bacilli S RelA SpoT domain protein yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT GHFFDFOM_00693 220668.lp_2222 1.29e-193 536.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,3F45D@33958|Lactobacillaceae 91061|Bacilli F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase GHFFDFOM_00694 220668.lp_2221 1.09e-222 613.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,3F4AU@33958|Lactobacillaceae 91061|Bacilli G Responsible for synthesis of pseudouridine from uracil yjbO GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 GHFFDFOM_00695 220668.lp_2220 2.51e-150 422.0 COG3142@1|root,COG3142@2|Bacteria,1TQYI@1239|Firmicutes,4HE1E@91061|Bacilli,3F4NZ@33958|Lactobacillaceae 91061|Bacilli P Participates in the control of copper homeostasis cutC - - ko:K06201 - - - - ko00000 - - - CutC GHFFDFOM_00696 220668.lp_2219 6.5e-246 675.0 COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,3F3RC@33958|Lactobacillaceae 91061|Bacilli G Lactonase, 7-bladed beta-propeller pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase GHFFDFOM_00697 220668.lp_2218 7.7e-75 224.0 COG3731@1|root,COG3731@2|Bacteria,1VGKB@1239|Firmicutes,4HNJN@91061|Bacilli,3F8EZ@33958|Lactobacillaceae 91061|Bacilli G PTS system glucitol/sorbitol-specific IIA component srlB - 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - PTSIIA_gutA GHFFDFOM_00698 220668.lp_2217 9.52e-264 724.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,3F418@33958|Lactobacillaceae 91061|Bacilli S AI-2E family transporter XK27_05220 - - - - - - - - - - - AI-2E_transport GHFFDFOM_00699 220668.lp_2216 4.82e-55 172.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HKK1@91061|Bacilli,3F7KX@33958|Lactobacillaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 GHFFDFOM_00700 220668.lp_2215 1.12e-207 573.0 COG0500@1|root,COG2226@2|Bacteria,1V1WE@1239|Firmicutes,4HGQ9@91061|Bacilli,3F4U3@33958|Lactobacillaceae 91061|Bacilli H Methyltransferase rrmA - 2.1.1.187 ko:K00563,ko:K10947 - - R07233 RC00003 ko00000,ko01000,ko03000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 GHFFDFOM_00702 220668.lp_2213 2.17e-302 827.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - iSB619.SA_RS01075 Branch_AA_trans GHFFDFOM_00703 220668.lp_2212 4.32e-148 417.0 COG2910@1|root,COG2910@2|Bacteria,1TZ3T@1239|Firmicutes,4HVUN@91061|Bacilli,3F5K7@33958|Lactobacillaceae 91061|Bacilli S NAD(P)H-binding - - - ko:K07118 - - - - ko00000 - - - NAD_binding_10 GHFFDFOM_00704 220668.lp_2211 1.41e-124 354.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,3F42Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase GHFFDFOM_00705 220668.lp_2210 0.0 1451.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,3F3JZ@33958|Lactobacillaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma GHFFDFOM_00706 220668.lp_2206 4.99e-224 618.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli,3F5FV@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein - - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA GHFFDFOM_00707 220668.lp_2205 3.22e-82 243.0 2DIRP@1|root,3040A@2|Bacteria,1TVPU@1239|Firmicutes,4IFNU@91061|Bacilli,3F6RY@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3397) - - - - - - - - - - - - DUF3397 GHFFDFOM_00708 220668.lp_2203 7.24e-101 292.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,3F6K3@33958|Lactobacillaceae 91061|Bacilli K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ GHFFDFOM_00709 220668.lp_2202 2.58e-226 624.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,3F3MF@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 GHFFDFOM_00710 220668.lp_2201 7.01e-76 228.0 COG4839@1|root,COG4839@2|Bacteria,1VCE5@1239|Firmicutes,4HM4W@91061|Bacilli,3F6KG@33958|Lactobacillaceae 91061|Bacilli D Cell division protein FtsL ftsL - - - - - - - - - - - DivIC GHFFDFOM_00711 220668.lp_2200 0.0 1359.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,3F47N@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase GHFFDFOM_00712 220668.lp_2199 2.81e-231 636.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,3F3YP@33958|Lactobacillaceae 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 GHFFDFOM_00713 220668.lp_2197 0.0 899.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,3F49W@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M GHFFDFOM_00714 220668.lp_2196 5e-253 695.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,3F4FW@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 GHFFDFOM_00715 220668.lp_2195 2.34e-208 576.0 COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,3F406@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 GHFFDFOM_00716 220668.lp_2194 3.55e-312 852.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,3F413@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA GHFFDFOM_00717 220668.lp_2193 9.39e-295 806.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,3F4V1@33958|Lactobacillaceae 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin GHFFDFOM_00718 220668.lp_2192 1.56e-93 273.0 COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,4HKIC@91061|Bacilli,3F7MQ@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 - ko:K09772 - - - - ko00000,ko03036 - - - SepF GHFFDFOM_00719 220668.lp_2191 6.45e-49 156.0 COG0762@1|root,COG0762@2|Bacteria,1VEKA@1239|Firmicutes,4HNJR@91061|Bacilli,3F843@33958|Lactobacillaceae 91061|Bacilli S YGGT family ylmG - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT GHFFDFOM_00720 220668.lp_2190 2.06e-187 520.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,3F48W@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein ylmH - - - - - - - - - - - S4 GHFFDFOM_00721 220668.lp_2189 6.52e-124 357.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,3F4IN@33958|Lactobacillaceae 91061|Bacilli D DivIVA domain protein divIVA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA GHFFDFOM_00722 220668.lp_2187 0.0 1905.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,3F3X4@33958|Lactobacillaceae 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS GHFFDFOM_00723 699248.SRA_00473 3.64e-101 304.0 COG1131@1|root,COG1131@2|Bacteria,1V0AH@1239|Firmicutes,4HD15@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein cylA - - ko:K11050 ko02010,map02010 M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1.130 - - ABC_tran GHFFDFOM_00724 1154757.Q5C_02675 1.47e-100 303.0 COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,4HJK7@91061|Bacilli,4AXTJ@81850|Leuconostocaceae 91061|Bacilli U ABC-2 type transporter - - - ko:K11051 ko02010,map02010 M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1.130 - - ABC2_membrane,ABC2_membrane_3 GHFFDFOM_00725 1122147.AUEH01000037_gene136 2.57e-47 157.0 COG3279@1|root,COG3279@2|Bacteria,1W04J@1239|Firmicutes,4HRMI@91061|Bacilli,3F6TA@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR GHFFDFOM_00726 699248.SRA_00488 2.05e-20 87.8 2DFFN@1|root,2ZRNX@2|Bacteria,1W679@1239|Firmicutes,4I0AX@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3021) - - - - - - - - - - - - DUF3021 GHFFDFOM_00727 220668.lp_2185 3.46e-242 665.0 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,3F4F7@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase GHFFDFOM_00728 220668.lp_2183 3.51e-125 357.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,3F53J@33958|Lactobacillaceae 91061|Bacilli L ADP-ribose pyrophosphatase nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX GHFFDFOM_00729 220668.lp_2182 7.74e-47 150.0 2DKSR@1|root,30AP7@2|Bacteria,1U6XV@1239|Firmicutes,4IGS4@91061|Bacilli,3F8PI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00730 220668.lp_2181 5.85e-158 443.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,3F4HE@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 GHFFDFOM_00731 220668.lp_2180 3.69e-278 760.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,3F3RF@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 GHFFDFOM_00732 220668.lp_2179 4.94e-75 224.0 2DHWG@1|root,32U9W@2|Bacteria,1VDSF@1239|Firmicutes,4HP9N@91061|Bacilli,3F7E3@33958|Lactobacillaceae 91061|Bacilli S Putative amino acid metabolism XK27_04120 - - - - - - - - - - - DUF1831 GHFFDFOM_00733 220668.lp_2178 3.19e-285 777.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,3F4N5@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans GHFFDFOM_00734 220668.lp_2177 9.64e-307 838.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,3F5BE@33958|Lactobacillaceae 91061|Bacilli P Potassium uptake protein ktrB - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH GHFFDFOM_00735 220668.lp_2176 9.37e-150 422.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,3F5G0@33958|Lactobacillaceae 91061|Bacilli P domain protein ktrA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N GHFFDFOM_00736 220668.lp_2175 4.17e-153 432.0 COG5492@1|root,COG5492@2|Bacteria,1W54S@1239|Firmicutes,4IF30@91061|Bacilli,3F5H0@33958|Lactobacillaceae 91061|Bacilli N WxL domain surface cell wall-binding - - - - - - - - - - - - WxL GHFFDFOM_00737 220668.lp_2174 1.22e-248 682.0 COG4072@1|root,COG4072@2|Bacteria,1VFEV@1239|Firmicutes,4HPF3@91061|Bacilli,3F470@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF916) - - - - - - - - - - - - DUF3324,DUF916 GHFFDFOM_00738 220668.lp_2173 0.0 927.0 COG5492@1|root,COG5492@2|Bacteria,1U5AN@1239|Firmicutes,4IF23@91061|Bacilli,3F5E8@33958|Lactobacillaceae 91061|Bacilli N domain, Protein - - - - - - - - - - - - Big_2,WxL GHFFDFOM_00739 220668.lp_2170 2.41e-157 441.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F3U3@33958|Lactobacillaceae 91061|Bacilli G phosphoglycerate mutase pgm6 - - - - - - - - - - - His_Phos_1 GHFFDFOM_00740 220668.lp_2169 1.02e-155 437.0 COG0457@1|root,COG0457@2|Bacteria,1VFGR@1239|Firmicutes,4IBSH@91061|Bacilli,3F4MD@33958|Lactobacillaceae 91061|Bacilli S repeat protein - - - - - - - - - - - - TPR_12,TPR_16,TPR_19,TPR_2,TPR_8 GHFFDFOM_00741 220668.lp_2168 0.0 1637.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,3F44X@33958|Lactobacillaceae 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 GHFFDFOM_00742 220668.lp_2166 5.35e-220 608.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HV42@91061|Bacilli,3FCBW@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs2 - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N GHFFDFOM_00743 220668.lp_2162 2.97e-162 476.0 COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1VG0Z@1239|Firmicutes,4HBE9@91061|Bacilli,3F50V@33958|Lactobacillaceae 91061|Bacilli M NlpC P60 family protein - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - LysM,NLPC_P60 GHFFDFOM_00744 220668.lp_2160 2.16e-39 130.0 29PG6@1|root,30ADU@2|Bacteria,1U6IE@1239|Firmicutes,4IGAR@91061|Bacilli,3F7Z6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00745 220668.lp_2159 2.43e-240 659.0 COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,4HBUD@91061|Bacilli,3F5GQ@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat GHFFDFOM_00746 220668.lp_2158 0.0 1097.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3TT@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL GHFFDFOM_00747 220668.lp_2157 4.86e-45 145.0 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli,3F807@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0356 family ykzG - - - - - - - - - - - DUF1447 GHFFDFOM_00748 220668.lp_2156 6.45e-111 319.0 2C389@1|root,2ZQCN@2|Bacteria,1VQPI@1239|Firmicutes,4I0G9@91061|Bacilli,3F79N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00749 220668.lp_2155 3.95e-132 374.0 COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HH0G@91061|Bacilli,3F3YH@33958|Lactobacillaceae 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase GHFFDFOM_00750 220668.lp_2154 2.98e-269 736.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PQ@91061|Bacilli,3F3JK@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase E1 component pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh GHFFDFOM_00751 1136177.KCA1_1824 6.35e-230 633.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HA4H@91061|Bacilli,3F4RV@33958|Lactobacillaceae 91061|Bacilli C Transketolase, C-terminal domain protein pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14590 Transket_pyr,Transketolase_C GHFFDFOM_00752 220668.lp_2152 2.36e-285 783.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,3F3RR@33958|Lactobacillaceae 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding GHFFDFOM_00753 220668.lp_2151 0.0 920.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,3F426@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase pdhD - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim GHFFDFOM_00754 220668.lp_2150 2.15e-209 580.0 COG0039@1|root,COG0039@2|Bacteria,1UFQZ@1239|Firmicutes,4IEWQ@91061|Bacilli,3F4RQ@33958|Lactobacillaceae 91061|Bacilli C L-malate dehydrogenase activity - - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - - GHFFDFOM_00755 220668.lp_2149 2.64e-62 191.0 COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli,3F80A@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0223 family yktA - - - - - - - - - - - UPF0223 GHFFDFOM_00756 220668.lp_2147 1.23e-177 495.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,3F5BB@33958|Lactobacillaceae 91061|Bacilli G Belongs to the inositol monophosphatase superfamily suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P GHFFDFOM_00757 220668.lp_2146 0.0 1199.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,3F3UK@33958|Lactobacillaceae 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 GHFFDFOM_00758 220668.lp_2145 9.43e-259 715.0 2BCCC@1|root,325XR@2|Bacteria,1UFIP@1239|Firmicutes,4IESV@91061|Bacilli,3F3X6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00759 220668.lp_1109 0.0 996.0 COG3051@1|root,COG3051@2|Bacteria,1TPN3@1239|Firmicutes,4HAE1@91061|Bacilli,3F4EA@33958|Lactobacillaceae 91061|Bacilli H Citrate (pro-3S)-lyase alpha chain citF - 2.8.3.10 ko:K01643 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - CitF GHFFDFOM_00760 220668.lp_1108 2.73e-209 579.0 COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,4HD40@91061|Bacilli,3F47Q@33958|Lactobacillaceae 91061|Bacilli G Belongs to the HpcH HpaI aldolase family citE - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI GHFFDFOM_00761 220668.lp_1107 1.23e-58 181.0 COG3052@1|root,COG3052@2|Bacteria,1VEZZ@1239|Firmicutes,4HNXD@91061|Bacilli,3F7FR@33958|Lactobacillaceae 91061|Bacilli C Covalent carrier of the coenzyme of citrate lyase citD - - ko:K01646 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001 - - - ACP GHFFDFOM_00762 220668.lp_1106 3.74e-242 666.0 COG3053@1|root,COG3053@2|Bacteria,1TSGQ@1239|Firmicutes,4HDAU@91061|Bacilli,3FB9D@33958|Lactobacillaceae 91061|Bacilli H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase citC - 6.2.1.22 ko:K01910 ko02020,map02020 - R04449 RC00012,RC00039 ko00000,ko00001,ko01000 - - - Citrate_ly_lig GHFFDFOM_00763 220668.lp_1105 1.92e-264 726.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,3F4GN@33958|Lactobacillaceae 91061|Bacilli C Malic enzyme, NAD binding domain mae - 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic GHFFDFOM_00764 220668.lp_1103 8.69e-230 632.0 COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,4HCAR@91061|Bacilli,3F4PP@33958|Lactobacillaceae 91061|Bacilli K sugar-binding domain protein citR - - - - - - - - - - - Sugar-bind GHFFDFOM_00765 220668.lp_1102 0.0 905.0 COG0471@1|root,COG0471@2|Bacteria,1TSGE@1239|Firmicutes,4HDE4@91061|Bacilli,3F4RH@33958|Lactobacillaceae 91061|Bacilli P Sodium:sulfate symporter transmembrane region citP - - ko:K03319 - - - - ko00000 2.A.47 - - Na_sulph_symp GHFFDFOM_00766 220668.lp_1101 7.56e-214 591.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F3RM@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N GHFFDFOM_00767 220668.lp_1098 1.18e-66 202.0 2EK0P@1|root,33DR7@2|Bacteria,1VKHU@1239|Firmicutes,4HP3S@91061|Bacilli,3F6X8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00768 220668.lp_1097 5.19e-223 615.0 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli,3F4B9@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family mntA - - ko:K19975,ko:K19976 ko02010,map02010 M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.15 - - ZnuA GHFFDFOM_00769 220668.lp_1096 3.54e-180 504.0 COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli,3F4JM@33958|Lactobacillaceae 91061|Bacilli U ABC 3 transport family mtsB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K19972,ko:K19976 ko02010,map02010 M00791,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.14,3.A.1.15.15,3.A.1.15.2 - - ABC-3 GHFFDFOM_00770 220668.lp_1095 2.04e-170 476.0 COG1121@1|root,COG1121@2|Bacteria,1TQJ3@1239|Firmicutes,4HA2W@91061|Bacilli,3F4VW@33958|Lactobacillaceae 91061|Bacilli P ABC transporter mntB - 3.6.3.35 ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 M00243,M00244,M00792 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.15 - - ABC_tran GHFFDFOM_00771 220668.lp_1093 7.77e-197 546.0 COG1767@1|root,COG1767@2|Bacteria,1TQGQ@1239|Firmicutes,4HGCS@91061|Bacilli,3F4SU@33958|Lactobacillaceae 91061|Bacilli H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase citG - 2.4.2.52 ko:K05966 ko02020,map02020 - R09675 RC00049,RC00063 ko00000,ko00001,ko01000 - - - CitG,CitX GHFFDFOM_00772 220668.lp_1092 1.81e-253 694.0 COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V27P@1239|Firmicutes,4I2JJ@91061|Bacilli,3F65V@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - AraC_binding,Cupin_2,HTH_18 GHFFDFOM_00773 220668.lp_1090 9.01e-227 624.0 COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,4HA3C@91061|Bacilli,3F5FD@33958|Lactobacillaceae 91061|Bacilli C Fumarate hydratase (Fumerase) ttdA - 4.2.1.32 ko:K03779 ko00630,map00630 - R00339 RC01382 ko00000,ko00001,ko01000 - - - Fumerase GHFFDFOM_00774 220668.lp_1089 1.41e-147 415.0 COG1838@1|root,COG1838@2|Bacteria,1TSJ8@1239|Firmicutes,4HHKR@91061|Bacilli 91061|Bacilli C Catalyzes the reversible hydration of fumarate to (S)- malate - - 4.2.1.2,4.2.1.32 ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R00339,R01082 RC00443,RC01382 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C GHFFDFOM_00775 220668.lp_1088 4.33e-69 209.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,3F7D5@33958|Lactobacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein yitW - - - - - - - - - - - FeS_assembly_P GHFFDFOM_00776 220668.lp_1087 0.0 910.0 COG0471@1|root,COG0471@2|Bacteria,1TSGE@1239|Firmicutes,4HDE4@91061|Bacilli,3F4RH@33958|Lactobacillaceae 91061|Bacilli P Sodium:sulfate symporter transmembrane region - - - ko:K03319 - - - - ko00000 2.A.47 - - Na_sulph_symp GHFFDFOM_00777 220668.lp_1086 1.82e-253 696.0 COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4HAKN@91061|Bacilli,3F4JH@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase GHFFDFOM_00778 220668.lp_1085 4.68e-235 647.0 COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,4HB03@91061|Bacilli,3F5B5@33958|Lactobacillaceae 91061|Bacilli E DAHP synthetase I family aroF - 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 GHFFDFOM_00779 220668.lp_1084 2.45e-213 589.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,3F4WM@33958|Lactobacillaceae 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_dh_N GHFFDFOM_00780 220668.lp_1083 0.0 1297.0 COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli,3F4IJ@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt2 - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N GHFFDFOM_00781 220668.lp_1082 7.79e-261 714.0 COG2055@1|root,COG2055@2|Bacteria,1TR0Z@1239|Firmicutes,4HB6X@91061|Bacilli,3F4JZ@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH2 MDH2 oxidoreductase family - - - - - - - - - - - - Ldh_2 GHFFDFOM_00782 220668.lp_1081 2.46e-235 648.0 COG3391@1|root,COG3391@2|Bacteria,1V841@1239|Firmicutes,4HITC@91061|Bacilli,3F50M@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - GHFFDFOM_00783 220668.lp_1079 1.21e-209 579.0 COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli,3F4II@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 yitS - - - - - - - - - - - DegV GHFFDFOM_00784 1136177.KCA1_0857 8.98e-86 253.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,3F656@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 GHFFDFOM_00785 1136177.KCA1_0856 4.58e-103 298.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,3F696@33958|Lactobacillaceae 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 GHFFDFOM_00786 220668.lp_1076 8.77e-194 536.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,3F4KC@33958|Lactobacillaceae 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 GHFFDFOM_00787 220668.lp_1075 2.39e-184 513.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,3F3UW@33958|Lactobacillaceae 91061|Bacilli U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ GHFFDFOM_00788 220668.lp_1074 2.01e-211 584.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli,3F48E@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran GHFFDFOM_00789 220668.lp_1073 1.98e-197 547.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli,3F3VD@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran GHFFDFOM_00790 220668.lp_1072 1.07e-264 726.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HA6Y@91061|Bacilli,3FB4B@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE GHFFDFOM_00791 220668.lp_1070 3.19e-194 541.0 COG4939@1|root,COG4939@2|Bacteria,1V3CW@1239|Firmicutes,4IR0T@91061|Bacilli,3F5C4@33958|Lactobacillaceae 91061|Bacilli S FMN_bind - - - - - - - - - - - - FMN_bind GHFFDFOM_00792 220668.lp_1069 0.0 1263.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,3F4N1@33958|Lactobacillaceae 91061|Bacilli C NADH dehydrogenase ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DoxX,Pyr_redox_2 GHFFDFOM_00793 220668.lp_1068 5.37e-112 322.0 COG5341@1|root,COG5341@2|Bacteria,1VCR8@1239|Firmicutes,4HMR5@91061|Bacilli,3F7R1@33958|Lactobacillaceae 91061|Bacilli S NusG domain II - - - - - - - - - - - - NusG_II GHFFDFOM_00794 220668.lp_1067 1.41e-122 350.0 COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,4HG1H@91061|Bacilli,3F3R8@33958|Lactobacillaceae 91061|Bacilli S Heptaprenyl diphosphate synthase component I hepA - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - Hpre_diP_synt_I GHFFDFOM_00795 220668.lp_1066 1.02e-233 643.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,3F4GC@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 - R09245,R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt GHFFDFOM_00796 220668.lp_1063 7.76e-81 240.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli,3F6GJ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 GHFFDFOM_00797 220668.lp_1062 2.19e-220 608.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli,3F3W6@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L GHFFDFOM_00798 1400520.LFAB_04735 7.71e-82 243.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,3F67D@33958|Lactobacillaceae 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 GHFFDFOM_00799 220668.lp_1060 9.65e-79 234.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli,3F6GN@33958|Lactobacillaceae 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 GHFFDFOM_00800 1136177.KCA1_0840 1.19e-45 147.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,3F7CW@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a GHFFDFOM_00801 220668.lp_1058 1.84e-160 449.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,3F3KB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid GHFFDFOM_00802 220668.lp_1056 5.95e-300 819.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli,3F4FV@33958|Lactobacillaceae 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY GHFFDFOM_00803 1136177.KCA1_0837 1.32e-91 268.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,3F675@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A GHFFDFOM_00804 220668.lp_1054 8.44e-34 116.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli,3F7ZU@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 GHFFDFOM_00805 1136177.KCA1_0835 5.32e-109 314.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,3F3VY@33958|Lactobacillaceae 91061|Bacilli J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C GHFFDFOM_00806 220668.lp_1052 1.75e-75 226.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,3F6KN@33958|Lactobacillaceae 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p GHFFDFOM_00807 220668.lp_1051 2.14e-123 352.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,3F4G5@33958|Lactobacillaceae 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 GHFFDFOM_00808 1136177.KCA1_0832 4.99e-88 258.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,3F64E@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 GHFFDFOM_00809 1136177.KCA1_0830 3.53e-123 351.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,3F3Q7@33958|Lactobacillaceae 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C GHFFDFOM_00810 220668.lp_1046 4.1e-67 203.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,3F6X5@33958|Lactobacillaceae 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 GHFFDFOM_00811 220668.lp_1045 2.98e-78 233.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli,3F6GT@33958|Lactobacillaceae 91061|Bacilli J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 GHFFDFOM_00812 1136177.KCA1_0827 1.96e-54 170.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli,3F7FX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 GHFFDFOM_00813 1136177.KCA1_0826 1.11e-33 116.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,3F82Z@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 GHFFDFOM_00814 220668.lp_1041 8.29e-100 289.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,3F653@33958|Lactobacillaceae 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 GHFFDFOM_00815 1136177.KCA1_0824 5.46e-152 427.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,3F3Q8@33958|Lactobacillaceae 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C GHFFDFOM_00816 1136177.KCA1_0823 3.59e-69 209.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,3F6K6@33958|Lactobacillaceae 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 GHFFDFOM_00817 1136177.KCA1_0822 1.85e-62 191.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,3F6XP@33958|Lactobacillaceae 91061|Bacilli J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 GHFFDFOM_00818 220668.lp_1036 6.61e-193 536.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,3F3XI@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C GHFFDFOM_00819 220668.lp_1035 2.27e-59 183.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli,3F6Z2@33958|Lactobacillaceae 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 GHFFDFOM_00820 220668.lp_1034 9.83e-141 398.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,3F3QD@33958|Lactobacillaceae 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 GHFFDFOM_00821 220668.lp_1033 4.34e-145 409.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli,3F45I@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 GHFFDFOM_00822 1136177.KCA1_0817 4.46e-66 201.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,3F6KC@33958|Lactobacillaceae 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 GHFFDFOM_00823 220668.lp_1027 0.0 1373.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,3F3JR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 GHFFDFOM_00824 1136177.KCA1_0815 1.19e-107 310.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli,3F3RX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 GHFFDFOM_00825 220668.lp_1025 4.19e-92 269.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli,3F64B@33958|Lactobacillaceae 91061|Bacilli J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 GHFFDFOM_00826 220668.lp_1023 1e-147 417.0 COG1989@1|root,COG1989@2|Bacteria,1W118@1239|Firmicutes,4HZ6B@91061|Bacilli,3F863@33958|Lactobacillaceae 91061|Bacilli NOU Bacterial Peptidase A24 N-terminal domain comC - 3.4.23.43 ko:K02236 - M00429 - - ko00000,ko00002,ko01000,ko02044 - - - DiS_P_DiS,Peptidase_A24 GHFFDFOM_00827 220668.lp_1022 0.0 2398.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,3F3KF@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 GHFFDFOM_00828 60520.HR47_09545 0.0 2359.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,3F4ET@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 GHFFDFOM_00829 220668.lp_1020 1.16e-140 397.0 COG1309@1|root,COG1309@2|Bacteria,1VD4H@1239|Firmicutes,4HNBF@91061|Bacilli,3F5VC@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GHFFDFOM_00830 60520.HR47_09535 0.0 1568.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,3F3RV@33958|Lactobacillaceae 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR GHFFDFOM_00831 220668.lp_1018 9.78e-102 295.0 COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli,3F53E@33958|Lactobacillaceae 91061|Bacilli K Belongs to the CtsR family ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03708 - - - - ko00000,ko03000 - - - CtsR GHFFDFOM_00832 220668.lp_2748 1.02e-113 325.0 29NX0@1|root,309V4@2|Bacteria,1U5RY@1239|Firmicutes,4IFG8@91061|Bacilli,3F6ER@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00833 220668.lp_2749 1.98e-65 199.0 29PAA@1|root,30A8F@2|Bacteria,1U6BS@1239|Firmicutes,4IG3D@91061|Bacilli,3F7J6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00834 1136177.KCA1_2246 4.79e-13 63.9 29PZH@1|root,30AXZ@2|Bacteria,1U78Y@1239|Firmicutes,4IH3T@91061|Bacilli,3F94V@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00835 220668.lp_2751 3.03e-299 815.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F4JX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase, class I patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 GHFFDFOM_00836 220668.lp_2753 1.16e-110 318.0 COG1051@1|root,COG1051@2|Bacteria,1UFAQ@1239|Firmicutes,4IFAZ@91061|Bacilli,3F648@33958|Lactobacillaceae 91061|Bacilli F belongs to the nudix hydrolase family - - - - - - - - - - - - - GHFFDFOM_00837 220668.lp_2754 7.21e-150 421.0 29DQI@1|root,300NC@2|Bacteria,1U55V@1239|Firmicutes,4IEX6@91061|Bacilli,3F4UQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00838 220668.lp_2755 1.72e-69 209.0 2EU16@1|root,33MI8@2|Bacteria,1VPSM@1239|Firmicutes,4HS7T@91061|Bacilli,3F6QA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00839 220668.lp_2757 0.0 1180.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,3F41N@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family nplT - 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 - R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Alpha-amylase_N,Malt_amylase_C GHFFDFOM_00840 220668.lp_2758 0.0 976.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,4H9R7@91061|Bacilli,3F3UF@33958|Lactobacillaceae 91061|Bacilli E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N GHFFDFOM_00841 220668.lp_2759 4.65e-186 517.0 COG0561@1|root,COG0561@2|Bacteria,1TR2E@1239|Firmicutes,4HCEA@91061|Bacilli,3F4G9@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 GHFFDFOM_00842 220668.lp_2760 4.72e-40 143.0 COG1357@1|root,COG1357@2|Bacteria,1VAPB@1239|Firmicutes,4HH43@91061|Bacilli,3FBAQ@33958|Lactobacillaceae 91061|Bacilli S Pentapeptide repeats (8 copies) - - - - - - - - - - - - Pentapeptide,Pentapeptide_4 GHFFDFOM_00843 220668.lp_2761 1.76e-143 405.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,3F59K@33958|Lactobacillaceae 91061|Bacilli S Maltose acetyltransferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac GHFFDFOM_00844 220668.lp_2762 5.38e-131 372.0 COG0494@1|root,COG0494@2|Bacteria,1VXC7@1239|Firmicutes,4HX58@91061|Bacilli,3F45R@33958|Lactobacillaceae 91061|Bacilli L Belongs to the Nudix hydrolase family - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX GHFFDFOM_00845 220668.lp_2763 2.26e-91 266.0 COG0537@1|root,COG0537@2|Bacteria,1VB6J@1239|Firmicutes,4HN1R@91061|Bacilli,3F6W7@33958|Lactobacillaceae 91061|Bacilli FG Scavenger mRNA decapping enzyme C-term binding - - - - - - - - - - - - HIT GHFFDFOM_00846 220668.lp_2764 1.62e-173 484.0 COG1028@1|root,COG1028@2|Bacteria,1U8IC@1239|Firmicutes,4HC26@91061|Bacilli,3F4X3@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 GHFFDFOM_00847 220668.lp_2765 3.94e-49 155.0 2E68Y@1|root,330X0@2|Bacteria,1VFBF@1239|Firmicutes,4HP3V@91061|Bacilli,3F810@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2829) XK27_01315 - - - - - - - - - - - DUF2829 GHFFDFOM_00848 220668.lp_2766 6.01e-270 738.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4H9V2@91061|Bacilli,3F4FK@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) ybhE - - ko:K09963 - - - - ko00000 - - - DUF871 GHFFDFOM_00849 220668.lp_2767 1.61e-296 807.0 COG4552@1|root,COG4552@2|Bacteria,1TRPM@1239|Firmicutes,4HD22@91061|Bacilli,3F5HJ@33958|Lactobacillaceae 91061|Bacilli S Sterol carrier protein domain - - - - - - - - - - - - Acetyltransf_9,SCP2_2 GHFFDFOM_00850 220668.lp_2768 6.73e-287 786.0 COG0477@1|root,COG2814@2|Bacteria,1TRZB@1239|Firmicutes,4HC28@91061|Bacilli,3F4VZ@33958|Lactobacillaceae 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 GHFFDFOM_00851 220668.lp_2770 7.54e-115 329.0 COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli,3F7V1@33958|Lactobacillaceae 91061|Bacilli S 3H domain yrxA - - ko:K07105 - - - - ko00000 - - - 3H,HTH_11 GHFFDFOM_00852 220668.lp_2771 0.0 914.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,3F3K7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP nadC2 - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase GHFFDFOM_00853 220668.lp_2772 2.13e-152 429.0 COG1309@1|root,COG1309@2|Bacteria,1V3R8@1239|Firmicutes,4HBEK@91061|Bacilli,3F6RQ@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_N GHFFDFOM_00854 220668.lp_2773 9.76e-234 650.0 COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli,3F40D@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 GHFFDFOM_00855 220668.lp_2774 4.29e-173 483.0 COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,4HBUK@91061|Bacilli,3F3VV@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_00856 220668.lp_2776 9.53e-317 863.0 COG3048@1|root,COG3048@2|Bacteria,1TPAH@1239|Firmicutes,4HANC@91061|Bacilli,3F4S1@33958|Lactobacillaceae 91061|Bacilli E Belongs to the serine threonine dehydratase family. DsdA subfamily dsdA - 4.3.1.18 ko:K01753 ko00260,map00260 - R00221 RC02600 ko00000,ko00001,ko01000 - - - PALP GHFFDFOM_00857 220668.lp_2777 0.0 1014.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family pbg4 - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 GHFFDFOM_00858 220668.lp_2778 0.0 1023.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family pbg5 - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 GHFFDFOM_00859 1136177.KCA1_2274 2.73e-73 220.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,3F6Z5@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose Cellobiose specific IIA subunit celC - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA GHFFDFOM_00860 1136177.KCA1_2275 1.86e-64 197.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,3F6GU@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit pts20B - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB GHFFDFOM_00861 220668.lp_2782 6.37e-169 471.0 COG2188@1|root,COG2188@2|Bacteria,1V54P@1239|Firmicutes,4IPPI@91061|Bacilli,3F5X0@33958|Lactobacillaceae 91061|Bacilli K UTRA gntR - - ko:K03489 - - - - ko00000,ko03000 - - - GntR,UTRA GHFFDFOM_00862 220668.lp_2783 1.4e-181 504.0 COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HNAP@91061|Bacilli,3F52I@33958|Lactobacillaceae 91061|Bacilli S glycosyl transferase family 2 epsV - - - - - - - - - - - Glycos_transf_2 GHFFDFOM_00863 220668.lp_2785 1.75e-156 439.0 COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,4HD4C@91061|Bacilli,3F50R@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family pgm7 - - - - - - - - - - - His_Phos_1 GHFFDFOM_00864 220668.lp_2786 7.63e-107 308.0 2CG6V@1|root,309UJ@2|Bacteria,1U5R2@1239|Firmicutes,4IFF2@91061|Bacilli,3F6C5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00865 220668.lp_2787 5.06e-196 543.0 COG0561@1|root,COG0561@2|Bacteria,1V8IN@1239|Firmicutes,4HJUX@91061|Bacilli,3F5CU@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - - - - - - - - - - - Hydrolase_3 GHFFDFOM_00866 220668.lp_2788 1.51e-235 649.0 COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,4HB4T@91061|Bacilli,3F455@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid ykpB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C GHFFDFOM_00867 220668.lp_2789 2.8e-204 567.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F423@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA GHFFDFOM_00868 220668.lp_2790 4.12e-226 623.0 COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,4HAW5@91061|Bacilli,3F4DF@33958|Lactobacillaceae 91061|Bacilli EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain serA1 - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C GHFFDFOM_00869 220668.lp_2792 3.78e-132 375.0 COG2085@1|root,COG2085@2|Bacteria,1V35D@1239|Firmicutes,4HFSW@91061|Bacilli,3F5EP@33958|Lactobacillaceae 91061|Bacilli S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored GHFFDFOM_00870 220668.lp_2793 0.0 914.0 28UXD@1|root,2ZH17@2|Bacteria,1W3NA@1239|Firmicutes,4HZFV@91061|Bacilli,3F5J6@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - - GHFFDFOM_00871 220668.lp_2794 1.17e-101 294.0 COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli,3F6HY@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin fld - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 GHFFDFOM_00872 220668.lp_2795 0.0 1905.0 COG3209@1|root,COG4886@1|root,COG3209@2|Bacteria,COG4886@2|Bacteria,1TT3P@1239|Firmicutes,4I28K@91061|Bacilli,3F4YY@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF5011) - - - - - - - - - - - - Big_3,DUF285,Gram_pos_anchor GHFFDFOM_00873 220668.lp_2796 0.0 1642.0 COG3087@1|root,COG3209@1|root,COG4886@1|root,COG3087@2|Bacteria,COG3209@2|Bacteria,COG4886@2|Bacteria,1UYD7@1239|Firmicutes,4HJI6@91061|Bacilli,3F7RJ@33958|Lactobacillaceae 91061|Bacilli M Bacterial surface protein 26-residue PARCEL repeat (3 repeats) - - - - - - - - - - - - Big_3,DUF285,Gram_pos_anchor,LRR_5,MucBP GHFFDFOM_00874 220668.lp_2797 4.3e-44 143.0 29PEY@1|root,30AD4@2|Bacteria,1U6HE@1239|Firmicutes,4IG9R@91061|Bacilli,3F7XG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00875 220668.lp_2798 2.55e-166 466.0 COG0710@1|root,COG0710@2|Bacteria,1UUXC@1239|Firmicutes,4IF2Z@91061|Bacilli,3F5GT@33958|Lactobacillaceae 91061|Bacilli E Type I 3-dehydroquinase aroC1 - 4.2.1.10 ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_I GHFFDFOM_00876 220668.lp_2799 0.0 927.0 COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,4HBIP@91061|Bacilli,3FCAH@33958|Lactobacillaceae 91061|Bacilli E amino acid ycaM - - - - - - - - - - - AA_permease_2 GHFFDFOM_00877 220668.lp_2800 2.45e-101 298.0 COG1846@1|root,COG1846@2|Bacteria,1U5TQ@1239|Firmicutes,4IFHR@91061|Bacilli,3F6HN@33958|Lactobacillaceae 91061|Bacilli K Winged helix DNA-binding domain - - - - - - - - - - - - MarR_2 GHFFDFOM_00878 220668.lp_2802 6.75e-211 582.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4H9XJ@91061|Bacilli,3F4IP@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase, aldo keto reductase family protein - - 1.1.1.346 ko:K06221 - - R08878 RC00089 ko00000,ko01000 - - - Aldo_ket_red GHFFDFOM_00879 220668.lp_2803 5.11e-208 575.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4H9XJ@91061|Bacilli,3FB4Q@33958|Lactobacillaceae 91061|Bacilli S reductase akr5f - 1.1.1.346 ko:K06221 - - R08878 RC00089 ko00000,ko01000 - - - Aldo_ket_red GHFFDFOM_00880 220668.lp_2804 1.3e-209 580.0 COG0583@1|root,COG0583@2|Bacteria,1UZXK@1239|Firmicutes,4HUWT@91061|Bacilli,3F41Q@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_00882 220668.lp_2806 1.97e-110 318.0 COG4720@1|root,COG4720@2|Bacteria,1VBBN@1239|Firmicutes,4HMK4@91061|Bacilli,3FBKC@33958|Lactobacillaceae 91061|Bacilli S Pfam:DUF3816 - - - - - - - - - - - - ECF-ribofla_trS GHFFDFOM_00883 220668.lp_2807 1.21e-306 835.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,3F48J@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b GHFFDFOM_00884 220668.lp_2809 1.54e-144 409.0 2A1CJ@1|root,30PJI@2|Bacteria,1U5QM@1239|Firmicutes,4IFEQ@91061|Bacilli,3F6BE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00885 220668.lp_2810 2.53e-228 638.0 COG3757@1|root,COG3757@2|Bacteria,1V2YH@1239|Firmicutes,4HKBF@91061|Bacilli,3F6FG@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25 GHFFDFOM_00886 220668.lp_2812 3.84e-185 514.0 COG4990@1|root,COG4990@2|Bacteria,1V3XE@1239|Firmicutes,4HJBT@91061|Bacilli,3F4HZ@33958|Lactobacillaceae 91061|Bacilli S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 GHFFDFOM_00887 220668.lp_2813 1.04e-120 344.0 COG5506@1|root,COG5506@2|Bacteria,1U595@1239|Firmicutes,4IF0H@91061|Bacilli,3F58I@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1694) - - - - - - - - - - - - DUF1694 GHFFDFOM_00888 220668.lp_2816 3.38e-150 423.0 COG1811@1|root,COG1811@2|Bacteria,1U5PM@1239|Firmicutes,4HAQH@91061|Bacilli,3FB60@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF554) - - - ko:K07150 - - - - ko00000 - - - DUF554 GHFFDFOM_00889 220668.lp_2817 8.38e-192 532.0 COG0789@1|root,COG0789@2|Bacteria,1V0RM@1239|Firmicutes,4IPXS@91061|Bacilli 91061|Bacilli KT helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 GHFFDFOM_00890 220668.lp_2818 3.41e-295 807.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,3F4Q2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltT - - ko:K03309,ko:K11102 - - - - ko00000,ko02000 2.A.23,2.A.23.1.1,2.A.23.1.2 - iYO844.BSU10220 SDF GHFFDFOM_00891 220668.lp_2820 1.86e-123 351.0 COG3477@1|root,COG3477@2|Bacteria,1VX0K@1239|Firmicutes,4HX2R@91061|Bacilli,3F6A5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1440) - - - ko:K08996 - - - - ko00000 - - - DUF1440 GHFFDFOM_00892 220668.lp_2822 3.59e-242 667.0 COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,3F3K5@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD GHFFDFOM_00893 220668.lp_2823 7.14e-157 440.0 COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,4HBXK@91061|Bacilli,3F4RP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_00894 220668.lp_2824 1.12e-116 335.0 COG3275@1|root,COG3275@2|Bacteria,1UZUT@1239|Firmicutes,4HMC0@91061|Bacilli,3F4G1@33958|Lactobacillaceae 91061|Bacilli T phosphorelay sensor kinase activity - - - ko:K16923 - M00582 - - ko00000,ko00002,ko02000 3.A.1.28 - - ECF_trnsprt GHFFDFOM_00895 220668.lp_2825 1.46e-240 660.0 COG1957@1|root,COG1957@2|Bacteria,1TRQQ@1239|Firmicutes,4IQRZ@91061|Bacilli,3F4ZB@33958|Lactobacillaceae 91061|Bacilli F Inosine-uridine preferring nucleoside hydrolase iunH3 - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro GHFFDFOM_00896 220668.lp_2826 3.55e-127 361.0 COG0262@1|root,COG0262@2|Bacteria,1VAUA@1239|Firmicutes,4HH71@91061|Bacilli,3F57D@33958|Lactobacillaceae 91061|Bacilli H RibD C-terminal domain ywjB - - - - - - - - - - - RibD_C GHFFDFOM_00897 220668.lp_2827 1.14e-257 709.0 COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,3F3QK@33958|Lactobacillaceae 91061|Bacilli P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family napA - - - - - - - - - - - Na_H_Exchanger GHFFDFOM_00898 60520.HR47_02060 5.21e-154 433.0 COG2364@1|root,COG2364@2|Bacteria,1V8E3@1239|Firmicutes,4HJ08@91061|Bacilli,3F4H9@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - GHFFDFOM_00899 220668.lp_2829 7.04e-198 551.0 COG0679@1|root,COG0679@2|Bacteria,1V0E3@1239|Firmicutes,4IQTM@91061|Bacilli,3F4BN@33958|Lactobacillaceae 91061|Bacilli S Membrane transport protein mleP3 - - ko:K07088 - - - - ko00000 - - - Mem_trans GHFFDFOM_00900 220668.lp_2830 1.29e-177 504.0 COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,4HFM9@91061|Bacilli,3FBTC@33958|Lactobacillaceae 91061|Bacilli E Fumarase C C-terminus aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 GHFFDFOM_00901 220668.lp_2830 4.18e-123 362.0 COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,4HFM9@91061|Bacilli,3FBTC@33958|Lactobacillaceae 91061|Bacilli E Fumarase C C-terminus aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 GHFFDFOM_00902 220668.lp_2833 1.54e-254 701.0 COG0477@1|root,COG2814@2|Bacteria,1TS0E@1239|Firmicutes,4HCEF@91061|Bacilli,3F5GE@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr GHFFDFOM_00903 220668.lp_2835 4.34e-138 391.0 COG1011@1|root,COG1011@2|Bacteria,1TQYM@1239|Firmicutes,4HPIM@91061|Bacilli,3F7UN@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 GHFFDFOM_00904 220668.lp_2835 5.18e-16 74.7 COG1011@1|root,COG1011@2|Bacteria,1TQYM@1239|Firmicutes,4HPIM@91061|Bacilli,3F7UN@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 GHFFDFOM_00905 220668.lp_2836 0.0 940.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 GHFFDFOM_00906 220668.lp_2839 5.97e-106 306.0 2C9UQ@1|root,309VR@2|Bacteria,1U5T4@1239|Firmicutes,4IFH1@91061|Bacilli,3F6FU@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4811) - - - - - - - - - - - - DUF4811 GHFFDFOM_00907 220668.lp_2840 7.69e-134 379.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,3F6YW@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain ydaF GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017198,GO:0018193,GO:0018209,GO:0019538,GO:0030920,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1990189 - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 GHFFDFOM_00908 220668.lp_2841 2.17e-222 615.0 COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,4HCCP@91061|Bacilli,3F4TY@33958|Lactobacillaceae 91061|Bacilli S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 GHFFDFOM_00909 220668.lp_2842 2.06e-194 539.0 COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,4HC4T@91061|Bacilli,3F4VC@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator rlrG - - ko:K21900 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate GHFFDFOM_00910 220668.lp_2843 0.0 1020.0 COG0438@1|root,COG0438@2|Bacteria,1VSNK@1239|Firmicutes,4HU8G@91061|Bacilli,3F4VP@33958|Lactobacillaceae 91061|Bacilli M Poly(Glycerol-phosphate) alpha-glucosyltransferase tagE5 - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Asp1,Glycos_transf_1 GHFFDFOM_00911 220668.lp_2844 0.0 948.0 COG0438@1|root,COG2849@1|root,COG0438@2|Bacteria,COG2849@2|Bacteria,1V09I@1239|Firmicutes,4HDDD@91061|Bacilli,3FBDH@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 tagE6 - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Asp1,Glyco_trans_A_1,Glyco_transf_4,Glycos_transf_1 GHFFDFOM_00912 220668.342242703 1.14e-79 251.0 COG1388@1|root,COG1388@2|Bacteria,1V773@1239|Firmicutes,4HIJG@91061|Bacilli,3F3JQ@33958|Lactobacillaceae 91061|Bacilli M LysM domain protein - - - - - - - - - - - - LysM,SLAP GHFFDFOM_00913 220668.lp_2847 3.85e-90 281.0 COG1388@1|root,COG1388@2|Bacteria,1U5BF@1239|Firmicutes,4IF2S@91061|Bacilli,3F5FT@33958|Lactobacillaceae 91061|Bacilli M LysM domain - - - - - - - - - - - - LysM GHFFDFOM_00914 220668.lp_2848 3.92e-120 342.0 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,3F6RF@33958|Lactobacillaceae 91061|Bacilli L Methyltransferase adaB GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567,ko:K10778,ko:K13531 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,Methyltransf_1N GHFFDFOM_00915 220668.lp_2849 9.97e-214 590.0 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,3F4J8@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein natA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 GHFFDFOM_00916 220668.lp_2850 7.88e-269 738.0 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,3F3KA@33958|Lactobacillaceae 91061|Bacilli CP ABC-2 family transporter protein natB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 GHFFDFOM_00917 220668.lp_2851 6.27e-166 465.0 COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,3F3VA@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short GHFFDFOM_00918 220668.lp_2852 1.64e-72 217.0 COG0599@1|root,COG0599@2|Bacteria,1V5CC@1239|Firmicutes,4HXN0@91061|Bacilli,3FBIG@33958|Lactobacillaceae 91061|Bacilli S Carboxymuconolactone decarboxylase family cmd - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD GHFFDFOM_00919 220668.lp_2853 2.27e-98 285.0 COG1917@1|root,COG1917@2|Bacteria,1V3TP@1239|Firmicutes,4HWR6@91061|Bacilli,3FBIH@33958|Lactobacillaceae 91061|Bacilli S Cupin domain yphH - - - - - - - - - - - Cupin_2 GHFFDFOM_00920 220668.lp_2854 1.27e-103 299.0 COG0789@1|root,COG0789@2|Bacteria,1VAT0@1239|Firmicutes,4HKQ1@91061|Bacilli,3FC64@33958|Lactobacillaceae 91061|Bacilli K transcriptional regulator, MerR family - - - - - - - - - - - - MerR_1 GHFFDFOM_00921 220668.lp_2855 2.52e-300 819.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 GHFFDFOM_00922 220668.lp_2856 0.0 1624.0 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,3F4HF@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease ylbB - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD GHFFDFOM_00923 60520.HR47_02180 1.74e-156 440.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli,3F3YU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_00925 60520.HR47_02190 2.93e-151 425.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli,3F42U@33958|Lactobacillaceae 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD GHFFDFOM_00926 220668.lp_2861 5.27e-140 396.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HGH2@91061|Bacilli,3FBEM@33958|Lactobacillaceae 91061|Bacilli S Maltose acetyltransferase thgA3 - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac GHFFDFOM_00927 220668.lp_2862 1.03e-150 423.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HMGQ@91061|Bacilli,3F56W@33958|Lactobacillaceae 91061|Bacilli U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 GHFFDFOM_00928 220668.lp_2863 1.58e-146 412.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HMGQ@91061|Bacilli,3F56W@33958|Lactobacillaceae 91061|Bacilli U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 GHFFDFOM_00929 220668.lp_2864 1.15e-109 315.0 29NXJ@1|root,309VP@2|Bacteria,1U5T3@1239|Firmicutes,4IFH0@91061|Bacilli,3F6FR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00930 220668.lp_2865 5.14e-111 319.0 COG0454@1|root,COG0456@2|Bacteria,1V3IC@1239|Firmicutes,4HH45@91061|Bacilli,3F7GI@33958|Lactobacillaceae 91061|Bacilli K GNAT family yvbK - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 GHFFDFOM_00931 220668.lp_2866 6.62e-48 153.0 29P9Q@1|root,30A7U@2|Bacteria,1U6B1@1239|Firmicutes,4IG2I@91061|Bacilli,3F7HP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00932 220668.lp_2867 2.81e-64 196.0 29P5Q@1|root,30A3V@2|Bacteria,1U65K@1239|Firmicutes,4IFVF@91061|Bacilli,3F748@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00933 220668.lp_2868 3.16e-144 407.0 COG0406@1|root,COG0406@2|Bacteria,1UUX3@1239|Firmicutes,4I2XG@91061|Bacilli,3F5PY@33958|Lactobacillaceae 91061|Bacilli G Histidine phosphatase superfamily (branch 1) pgm8 - - - - - - - - - - - His_Phos_1 GHFFDFOM_00934 220668.lp_2870 1.49e-83 247.0 291WS@1|root,2ZPGE@2|Bacteria,1V42S@1239|Firmicutes,4ISVW@91061|Bacilli,3F78I@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 GHFFDFOM_00935 220668.lp_3484 3.99e-107 315.0 COG3250@1|root,COG3250@2|Bacteria,1TRVA@1239|Firmicutes,4HFMH@91061|Bacilli,3F51Z@33958|Lactobacillaceae 91061|Bacilli G beta-galactosidase lacM - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N GHFFDFOM_00936 220668.lp_3485 0.0 1508.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,3F3RU@33958|Lactobacillaceae 91061|Bacilli G alpha-galactosidase melA GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009987,GO:0010033,GO:0015925,GO:0016043,GO:0016052,GO:0016787,GO:0016798,GO:0022607,GO:0042221,GO:0043933,GO:0044085,GO:0044238,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901545,GO:1901575,GO:1901700 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase GHFFDFOM_00937 220668.lp_3486 0.0 1228.0 COG2190@1|root,COG2211@1|root,COG2190@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HCDS@91061|Bacilli,3F3P7@33958|Lactobacillaceae 91061|Bacilli G Transporter lacP - - ko:K11104,ko:K16209 - - - - ko00000,ko02000 2.A.2.1,2.A.2.2 - - MFS_2,PTS_EIIA_1 GHFFDFOM_00938 220668.lp_3487 4.27e-253 693.0 COG2017@1|root,COG2017@2|Bacteria,1V5UK@1239|Firmicutes,4HTRY@91061|Bacilli,3FC7G@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of alpha and beta anomers of maltose galM3 - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim GHFFDFOM_00939 220668.lp_3488 1.5e-231 638.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,3F3PB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator galR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 GHFFDFOM_00940 220668.lp_3489 8.93e-249 682.0 COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,4HAZ2@91061|Bacilli,3F414@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase family protein tas3 - - ko:K19265 - - - - ko00000,ko01000 - - - Aldo_ket_red GHFFDFOM_00941 220668.lp_3490 2.02e-85 251.0 COG3576@1|root,COG3576@2|Bacteria,1VGE7@1239|Firmicutes,4HNE7@91061|Bacilli,3F6YB@33958|Lactobacillaceae 91061|Bacilli S pyridoxamine 5-phosphate - - - - - - - - - - - - Putative_PNPOx GHFFDFOM_00942 220668.lp_3491 0.0 1511.0 COG0431@1|root,COG1053@1|root,COG0431@2|Bacteria,COG1053@2|Bacteria,1TTD3@1239|Firmicutes,4HT4K@91061|Bacilli,3F5DN@33958|Lactobacillaceae 91061|Bacilli C FAD binding domain - - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FMN_bind,FMN_red GHFFDFOM_00943 220668.lp_3492 2.49e-228 629.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HHVC@91061|Bacilli,3F5ID@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE3 - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE GHFFDFOM_00944 60520.HR47_11135 6.76e-168 470.0 COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,4HDMG@91061|Bacilli,3F4TX@33958|Lactobacillaceae 91061|Bacilli E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate aroD - 4.2.1.10 ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_I GHFFDFOM_00945 60520.HR47_11130 4.63e-275 754.0 COG2271@1|root,COG2271@2|Bacteria,1UI3V@1239|Firmicutes,4HBYF@91061|Bacilli,3FBSK@33958|Lactobacillaceae 91061|Bacilli G Transporter - - - - - - - - - - - - MFS_1 GHFFDFOM_00946 60520.HR47_11125 1.66e-215 594.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,3F4WM@33958|Lactobacillaceae 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_dh_N GHFFDFOM_00947 60520.HR47_11120 5.79e-209 578.0 COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HFSV@91061|Bacilli,3F48I@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_00948 60520.HR47_11115 4.74e-268 736.0 COG2271@1|root,COG2271@2|Bacteria,1UI3V@1239|Firmicutes,4ISEV@91061|Bacilli,3F3ZF@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 GHFFDFOM_00949 220668.lp_3504 2.09e-83 246.0 2C4GV@1|root,30A1B@2|Bacteria,1U62A@1239|Firmicutes,4IFRA@91061|Bacilli,3F6V4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_00950 220668.lp_3505 2.63e-200 553.0 COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,4IPXU@91061|Bacilli,3F3ZG@33958|Lactobacillaceae 91061|Bacilli S Putative esterase estA - - - - - - - - - - - Esterase GHFFDFOM_00951 220668.lp_3506 5.44e-174 485.0 COG2188@1|root,COG2188@2|Bacteria,1VCJ9@1239|Firmicutes,4HM7V@91061|Bacilli,3F6DC@33958|Lactobacillaceae 91061|Bacilli K UTRA domain - - - - - - - - - - - - GntR,UTRA GHFFDFOM_00952 220668.lp_3507 0.0 864.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F54Z@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane pts29C - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC GHFFDFOM_00953 220668.lp_3508 2.93e-210 583.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,3F4T1@33958|Lactobacillaceae 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 GHFFDFOM_00954 220668.lp_3509 1.69e-202 562.0 COG2971@1|root,COG2971@2|Bacteria,1V38W@1239|Firmicutes,4HGPI@91061|Bacilli,3F5MG@33958|Lactobacillaceae 91061|Bacilli G BadF/BadG/BcrA/BcrD ATPase family - - - - - - - - - - - - BcrAD_BadFG GHFFDFOM_00955 220668.lp_3510 2.26e-269 736.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4H9V2@91061|Bacilli,3F4FK@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) - - - ko:K09963 - - - - ko00000 - - - DUF871 GHFFDFOM_00956 220668.lp_3512 0.0 997.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglH - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 GHFFDFOM_00957 220668.lp_3513 0.0 1157.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system bglP - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC GHFFDFOM_00958 220668.lp_3514 3.72e-200 554.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,3F4SJ@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain bglG4 - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD GHFFDFOM_00959 220668.lp_3525 0.0 1003.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family pbg9 - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 GHFFDFOM_00960 220668.lp_3526 0.0 994.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglH - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 GHFFDFOM_00961 220668.lp_3527 0.0 1268.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system pts33BCA - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC GHFFDFOM_00962 220668.lp_3529 1.3e-203 563.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,3F4SJ@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain bglG5 - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD GHFFDFOM_00963 220668.lp_3530 0.0 1478.0 COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,3F3PG@33958|Lactobacillaceae 91061|Bacilli G hydrolase, family 65, central catalytic treP - 2.4.1.64 ko:K05342 ko00500,ko01100,map00500,map01100 - R02727 RC00049 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m GHFFDFOM_00964 220668.lp_3531 2.66e-222 614.0 COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,4HBNT@91061|Bacilli,3F5CG@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LacI family cytR - - ko:K02529,ko:K03604 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 GHFFDFOM_00965 220668.lp_3533 0.0 936.0 COG2211@1|root,COG2211@2|Bacteria,1TRP7@1239|Firmicutes,4HCUK@91061|Bacilli,3F3YZ@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 GHFFDFOM_00966 220668.lp_3534 0.0 1596.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HB1D@91061|Bacilli,3F4CE@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 31 family agl - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31 GHFFDFOM_00968 220668.lp_3536 1.15e-236 650.0 COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,4HC4Y@91061|Bacilli,3F4NH@33958|Lactobacillaceae 91061|Bacilli M Linear amide C-N hydrolase, choloylglycine hydrolase family protein cbh - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH GHFFDFOM_00969 220668.lp_3537 9e-187 520.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,3F55S@33958|Lactobacillaceae 91061|Bacilli S hydrolase yxeH - - - - - - - - - - - Hydrolase_3 GHFFDFOM_00970 220668.lp_3538 0.0 1325.0 COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli,3F4IJ@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N GHFFDFOM_00971 220668.lp_3539 8.34e-147 414.0 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,4HA8G@91061|Bacilli,3F3X3@33958|Lactobacillaceae 91061|Bacilli F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA GHFFDFOM_00972 60520.HR47_11000 4.66e-164 459.0 COG0036@1|root,COG0036@2|Bacteria,1TT1C@1239|Firmicutes,4HDTC@91061|Bacilli,3F5AN@33958|Lactobacillaceae 91061|Bacilli G Ribulose-phosphate 3 epimerase family alsE - - ko:K17195 ko00051,ko01120,map00051,map01120 - R09031 RC03111 ko00000,ko00001,ko01000 - - - Ribul_P_3_epim GHFFDFOM_00973 60520.HR47_10995 3.64e-224 622.0 COG1299@1|root,COG1299@2|Bacteria,1TPKU@1239|Firmicutes,4H9XS@91061|Bacilli,3F52Q@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase System - - - ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.2.1 - - PTS_EIIC GHFFDFOM_00974 60520.HR47_10990 6.25e-63 193.0 COG1445@1|root,COG1445@2|Bacteria,1VASC@1239|Firmicutes,4HKYF@91061|Bacilli,3F7K8@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.202 ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_IIB GHFFDFOM_00975 60520.HR47_10985 1.91e-98 286.0 COG1762@1|root,COG1762@2|Bacteria,1V5TG@1239|Firmicutes,4HHQJ@91061|Bacilli,3FCBE@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.202 ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 GHFFDFOM_00976 356829.BITS_1324 2.28e-08 57.0 2BIQA@1|root,32CXN@2|Bacteria,2GTDU@201174|Actinobacteria,4D1IN@85004|Bifidobacteriales 201174|Actinobacteria H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - - - - - - - - - - PTS_EIIA_2 GHFFDFOM_00977 60520.HR47_10975 2.67e-311 853.0 COG3711@1|root,COG3711@2|Bacteria,1TSGM@1239|Firmicutes,4HB3W@91061|Bacilli,3F482@33958|Lactobacillaceae 91061|Bacilli K PRD domain - - - ko:K02538 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB GHFFDFOM_00978 220668.lp_1156 1.82e-53 175.0 COG4814@1|root,COG4814@2|Bacteria,1V8NG@1239|Firmicutes,4HJ22@91061|Bacilli,3F41V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 GHFFDFOM_00979 220668.lp_1155 7.06e-307 837.0 COG1455@1|root,COG1455@2|Bacteria,1V5SI@1239|Firmicutes,4HJTK@91061|Bacilli,3F3Z5@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane pts13C - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC GHFFDFOM_00980 220668.lp_1154 0.0 1464.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9ZI@91061|Bacilli,3F4Y1@33958|Lactobacillaceae 91061|Bacilli P E1-E2 ATPase yfgQ - - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - E1-E2_ATPase,Hydrolase GHFFDFOM_00981 220668.lp_1153 5.56e-130 369.0 COG1309@1|root,COG1309@2|Bacteria,1V1DM@1239|Firmicutes,4HG0Y@91061|Bacilli,3F5CS@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family yobS GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N,WHG GHFFDFOM_00982 220668.lp_1151 0.0 898.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F41R@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_2 - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr GHFFDFOM_00983 220668.lp_1150 1.59e-242 666.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,3F447@33958|Lactobacillaceae 91061|Bacilli G Lipid kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat GHFFDFOM_00984 220668.lp_1149 0.0 943.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,3F44H@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey GHFFDFOM_00985 220668.lp_1148 0.0 954.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,3F4BK@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase GHFFDFOM_00986 220668.lp_1147 5.11e-67 203.0 COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,3F7XB@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln GHFFDFOM_00987 220668.lp_1146 9.48e-263 722.0 COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,3F3KI@33958|Lactobacillaceae 91061|Bacilli S sex pheromone camS - - - - - - - - - - - CamS GHFFDFOM_00988 220668.lp_1145 0.0 1306.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,3F43C@33958|Lactobacillaceae 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 GHFFDFOM_00989 220668.lp_1144 0.0 1471.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3F400@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C GHFFDFOM_00990 220668.lp_1141 2.81e-279 763.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4HJI4@91061|Bacilli,3FC8U@33958|Lactobacillaceae 91061|Bacilli F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purK2 - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp GHFFDFOM_00991 220668.lp_1140 1.13e-120 345.0 COG4843@1|root,COG4843@2|Bacteria,1V14J@1239|Firmicutes,4HCBK@91061|Bacilli,3F4SX@33958|Lactobacillaceae 91061|Bacilli S UPF0316 protein yebE - - - - - - - - - - - DUF2179 GHFFDFOM_00992 220668.lp_1139 5.76e-134 380.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli,3F49S@33958|Lactobacillaceae 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran GHFFDFOM_00993 220668.lp_1138 9.78e-146 411.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIY4@91061|Bacilli,3F584@33958|Lactobacillaceae 91061|Bacilli NU mannosyl-glycoprotein acmA - 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,SH3_8,YceG GHFFDFOM_00994 220668.lp_1136 3.86e-235 646.0 COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,4HAPJ@91061|Bacilli,3F4XH@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA GHFFDFOM_00995 220668.lp_1135 8.5e-213 588.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F3JM@33958|Lactobacillaceae 91061|Bacilli H 1,4-dihydroxy-2-naphthoate menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA GHFFDFOM_00996 220668.lp_1134 4.87e-234 644.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,3F4GC@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt GHFFDFOM_00997 60520.HR47_09980 1.89e-208 579.0 COG3786@1|root,COG3786@2|Bacteria,1V2TG@1239|Firmicutes,4IPPW@91061|Bacilli,3FBDS@33958|Lactobacillaceae 91061|Bacilli S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD GHFFDFOM_00998 220668.lp_1129 0.0 1157.0 COG4987@1|root,COG4987@2|Bacteria,1UHN5@1239|Firmicutes,4HAAB@91061|Bacilli,3F4PG@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC cydD - - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran GHFFDFOM_00999 220668.lp_1128 0.0 1106.0 COG4988@1|root,COG4988@2|Bacteria,1TQ1P@1239|Firmicutes,4HAN0@91061|Bacilli,3F451@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD cydC GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran GHFFDFOM_01000 220668.lp_1126 7.76e-234 644.0 COG1294@1|root,COG1294@2|Bacteria,1TRYV@1239|Firmicutes,4H9KF@91061|Bacilli,3F40S@33958|Lactobacillaceae 91061|Bacilli C Cytochrome d ubiquinol oxidase subunit II cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - iYO844.BSU38750 Cyt_bd_oxida_II GHFFDFOM_01001 220668.lp_1125 0.0 948.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,3F4MJ@33958|Lactobacillaceae 91061|Bacilli C ubiquinol oxidase cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I GHFFDFOM_01002 220668.lp_1124 0.0 1192.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F4RM@33958|Lactobacillaceae 91061|Bacilli S Alpha beta - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4,Peptidase_S15 GHFFDFOM_01003 220668.lp_1123 1.23e-32 113.0 29P8R@1|root,30A6V@2|Bacteria,1U69S@1239|Firmicutes,4IG0X@91061|Bacilli,3F7E0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF2187 GHFFDFOM_01004 220668.lp_1121 6.21e-128 364.0 COG4684@1|root,COG4684@2|Bacteria,1VB4T@1239|Firmicutes,4HMUC@91061|Bacilli,3F497@33958|Lactobacillaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt GHFFDFOM_01005 220668.lp_1120 2.14e-313 857.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F3QY@33958|Lactobacillaceae 91061|Bacilli E Amino Acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 GHFFDFOM_01006 220668.lp_1119 2.6e-212 588.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HDX5@91061|Bacilli,3F3S0@33958|Lactobacillaceae 91061|Bacilli S Sodium Bile acid symporter family mleP2 - - ko:K07088 - - - - ko00000 - - - Mem_trans GHFFDFOM_01007 220668.lp_1118 0.0 1062.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4HBF1@91061|Bacilli,3F3RH@33958|Lactobacillaceae 91061|Bacilli C Malic enzyme mleS GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0030145,GO:0036094,GO:0043167,GO:0043169,GO:0043464,GO:0044237,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.1.1.38,4.1.1.101 ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 - R00214,R11074 RC00105,RC00282 ko00000,ko00001,ko01000 - - - Malic_M,malic GHFFDFOM_01008 220668.lp_1116 2.65e-214 592.0 COG0583@1|root,COG0583@2|Bacteria,1V5VW@1239|Firmicutes,4HHDY@91061|Bacilli,3F5D2@33958|Lactobacillaceae 91061|Bacilli K LysR family mleR - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_01009 220668.lp_1115 3.06e-205 568.0 COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,4HB94@91061|Bacilli,3FC6N@33958|Lactobacillaceae 91061|Bacilli K LysR family transcriptional regulator mleR2 - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_01010 220668.lp_1114 1.98e-122 349.0 COG3697@1|root,COG3697@2|Bacteria,1VB3E@1239|Firmicutes,4HMZ5@91061|Bacilli,3F74S@33958|Lactobacillaceae 91061|Bacilli HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase citX - 2.7.7.61 ko:K05964 ko02020,map02020 - R10706 - ko00000,ko00001,ko01000 - - - CitX GHFFDFOM_01011 220668.lp_1113 0.0 905.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,3F3KJ@33958|Lactobacillaceae 91061|Bacilli C FAD binding domain frdA - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2 GHFFDFOM_01012 220668.lp_1112 0.0 888.0 COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,3F3K0@33958|Lactobacillaceae 91061|Bacilli C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09430 FumaraseC_C,Lyase_1 GHFFDFOM_01013 1133569.AHYZ01000062_gene1495 2.05e-231 643.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,3F4TJ@33958|Lactobacillaceae 91061|Bacilli L PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,RVT_1 GHFFDFOM_01014 1133569.AHYZ01000062_gene1495 1.38e-19 87.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,3F4TJ@33958|Lactobacillaceae 91061|Bacilli L PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,RVT_1 GHFFDFOM_01016 1400520.LFAB_11500 3.47e-33 126.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_19,HTH_3,HTH_31 GHFFDFOM_01017 220668.lp_1642 5.6e-43 141.0 2FI7A@1|root,349ZW@2|Bacteria,1W0B2@1239|Firmicutes,4HY9R@91061|Bacilli,3F7DI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - EntA_Immun GHFFDFOM_01018 220668.lp_1643 0.0 3737.0 COG3266@1|root,COG5295@1|root,COG3266@2|Bacteria,COG5295@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - Gram_pos_anchor,MucBP GHFFDFOM_01019 220668.lp_1645 1.1e-112 323.0 2DPIQ@1|root,3328X@2|Bacteria,1VFYC@1239|Firmicutes,4HNHQ@91061|Bacilli,3F6VH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - AP2 GHFFDFOM_01020 220668.lp_1648 1.18e-178 498.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCEU@91061|Bacilli,3FC35@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system ecsA_2 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_01021 220668.lp_1649 0.0 960.0 28MBB@1|root,2ZAPV@2|Bacteria,1TSZA@1239|Firmicutes,4HDKH@91061|Bacilli,3F4FX@33958|Lactobacillaceae 91061|Bacilli - - XK27_00765 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - GHFFDFOM_01022 220668.lp_1652 0.0 938.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,3F4RG@33958|Lactobacillaceae 91061|Bacilli EH Anthranilate synthase component I, N terminal region trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind GHFFDFOM_01023 220668.lp_1653 8.08e-135 382.0 COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,3F4C7@33958|Lactobacillaceae 91061|Bacilli EH Peptidase C26 trpG - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase GHFFDFOM_01024 220668.lp_1654 2.45e-225 623.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,3F50X@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 GHFFDFOM_01025 220668.lp_1655 2.69e-162 457.0 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HDZQ@91061|Bacilli,3F5AK@33958|Lactobacillaceae 91061|Bacilli E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS GHFFDFOM_01026 220668.lp_1656 6.14e-140 396.0 COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,4HN68@91061|Bacilli,3F4B6@33958|Lactobacillaceae 91061|Bacilli E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI GHFFDFOM_01027 220668.lp_1657 1.04e-286 783.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli,3F4DT@33958|Lactobacillaceae 91061|Bacilli E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22640 PALP GHFFDFOM_01028 220668.lp_1658 4.82e-183 509.0 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli,3F50S@33958|Lactobacillaceae 91061|Bacilli E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA GHFFDFOM_01029 220668.lp_1659 1.69e-125 357.0 COG1335@1|root,COG1335@2|Bacteria,1V347@1239|Firmicutes,4HGFM@91061|Bacilli,3F716@33958|Lactobacillaceae 91061|Bacilli Q Isochorismatase family entB - - - - - - - - - - - Isochorismatase GHFFDFOM_01030 220668.lp_1660 3.53e-227 625.0 COG0604@1|root,COG0604@2|Bacteria,1UYWR@1239|Firmicutes,4HDC6@91061|Bacilli,3F5V1@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N GHFFDFOM_01031 220668.lp_1665 8.04e-254 696.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,3F42F@33958|Lactobacillaceae 91061|Bacilli E alcohol dehydrogenase adhB - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N GHFFDFOM_01032 220668.lp_1667 2.2e-79 236.0 2A1GT@1|root,30PQE@2|Bacteria,1U68C@1239|Firmicutes,4IFZ2@91061|Bacilli,3F7AG@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1648) - - - - - - - - - - - - DUF1648 GHFFDFOM_01033 220668.lp_1668 6.84e-186 517.0 COG4221@1|root,COG4221@2|Bacteria,1TQDY@1239|Firmicutes,4HBS5@91061|Bacilli,3FBSM@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family yneD - - - - - - - - - - - adh_short GHFFDFOM_01034 220668.lp_1669 3.81e-228 629.0 COG2207@1|root,COG2207@2|Bacteria,1UI1Z@1239|Firmicutes,4HC2Y@91061|Bacilli,3F4Q1@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator yneE - - - - - - - - - - - Arabinose_bd,HTH_18 GHFFDFOM_01035 220668.lp_1670 8.55e-99 287.0 COG0764@1|root,COG0764@2|Bacteria,1V3UN@1239|Firmicutes,4HHYD@91061|Bacilli,3FCD6@33958|Lactobacillaceae 91061|Bacilli I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA GHFFDFOM_01036 220668.lp_1671 9.77e-231 635.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,3F3XP@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C GHFFDFOM_01037 220668.lp_1672 1.06e-48 155.0 COG0236@1|root,COG0236@2|Bacteria,1VGIY@1239|Firmicutes,4HP0V@91061|Bacilli,3F7ZJ@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding GHFFDFOM_01038 220668.lp_1673 2.97e-216 597.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,3F3W9@33958|Lactobacillaceae 91061|Bacilli I Malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 GHFFDFOM_01039 220668.lp_1674 1.26e-162 456.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,3F4RI@33958|Lactobacillaceae 91061|Bacilli IQ reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 GHFFDFOM_01040 220668.lp_1675 1.54e-289 791.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,3F51H@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt GHFFDFOM_01041 220668.lp_1676 2.14e-95 279.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,3F7M1@33958|Lactobacillaceae 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl GHFFDFOM_01042 220668.lp_1677 1.71e-91 268.0 COG0764@1|root,COG0764@2|Bacteria,1VXBZ@1239|Firmicutes,4HXVK@91061|Bacilli,3F6TF@33958|Lactobacillaceae 91061|Bacilli I FabA-like domain fabZ2 - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA GHFFDFOM_01043 220668.lp_1678 0.0 901.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,3F3PT@33958|Lactobacillaceae 91061|Bacilli I Acetyl-CoA carboxylase biotin carboxylase subunit accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 GHFFDFOM_01044 220668.lp_1679 6.43e-203 561.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,3F3T6@33958|Lactobacillaceae 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans GHFFDFOM_01045 220668.lp_1680 4.82e-179 499.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,3F496@33958|Lactobacillaceae 91061|Bacilli I alpha subunit accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA GHFFDFOM_01046 220668.lp_1681 1.88e-174 487.0 COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli,3F4AQ@33958|Lactobacillaceae 91061|Bacilli I Enoyl- acyl-carrier-protein reductase NADH fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 GHFFDFOM_01047 220668.lp_1682 1.75e-129 367.0 COG2091@1|root,COG2091@2|Bacteria,1VK9G@1239|Firmicutes,4HRUX@91061|Bacilli,3F71W@33958|Lactobacillaceae 91061|Bacilli H Belongs to the P-Pant transferase superfamily - - - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS GHFFDFOM_01048 220668.lp_1684 3.64e-162 455.0 COG1811@1|root,COG1811@2|Bacteria,1TQWV@1239|Firmicutes,4IQYF@91061|Bacilli,3FB61@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF554) - - - ko:K07150 - - - - ko00000 - - - DUF554 GHFFDFOM_01049 220668.lp_1685 3.73e-207 573.0 COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,4HWQQ@91061|Bacilli,3F4CY@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_01050 220668.lp_1686 4.94e-114 327.0 COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,3F6A3@33958|Lactobacillaceae 91061|Bacilli I Thioesterase superfamily ykhA - - - - - - - - - - - 4HBT GHFFDFOM_01051 220668.lp_1687 8.88e-246 676.0 COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,3F5GW@33958|Lactobacillaceae 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA_2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase GHFFDFOM_01052 220668.lp_1688 1.49e-121 347.0 COG1309@1|root,COG1309@2|Bacteria,1VHWM@1239|Firmicutes,4IFMJ@91061|Bacilli,3F6Q3@33958|Lactobacillaceae 91061|Bacilli K transcriptional regulator - - - - - - - - - - - - TetR_N GHFFDFOM_01053 220668.lp_1689 0.0 1046.0 COG0477@1|root,COG2211@1|root,COG0477@2|Bacteria,COG2211@2|Bacteria,1TPV3@1239|Firmicutes,4HCJN@91061|Bacilli,3F5DE@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 GHFFDFOM_01054 220668.lp_1690 1.14e-193 538.0 COG0330@1|root,COG0330@2|Bacteria,1TRN5@1239|Firmicutes,4HA6G@91061|Bacilli,3F4ES@33958|Lactobacillaceae 91061|Bacilli O Band 7 protein - - - - - - - - - - - - Band_7 GHFFDFOM_01055 1158601.I585_04156 5.45e-84 267.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HEI7@91061|Bacilli,4B1EA@81852|Enterococcaceae 91061|Bacilli L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase GHFFDFOM_01058 1423734.JCM14202_3583 1.19e-13 65.9 2DKT3@1|root,30AQA@2|Bacteria,1U6Z9@1239|Firmicutes,4IGTI@91061|Bacilli,3F8RG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01060 220668.lp_1694 4.97e-70 211.0 29PKS@1|root,30C1A@2|Bacteria,1U76E@1239|Firmicutes,4IH15@91061|Bacilli,3F919@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01061 220668.lp_1695 2.02e-39 130.0 29EYP@1|root,301WG@2|Bacteria,1U773@1239|Firmicutes,4IH1X@91061|Bacilli,3F925@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01062 220668.lp_2231a 4.51e-84 248.0 29P79@1|root,30A5C@2|Bacteria,1U67W@1239|Firmicutes,4IFYK@91061|Bacilli,3F79S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01063 220668.lp_2231b 2e-98 285.0 COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli,3F6AN@33958|Lactobacillaceae 91061|Bacilli J general stress protein yugI - - ko:K07570,ko:K07571 - - - - ko00000 - - - S1 GHFFDFOM_01064 220668.lp_2231c 5.16e-141 397.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,3F3TI@33958|Lactobacillaceae 91061|Bacilli G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Hydrolase_3,Pro_isomerase GHFFDFOM_01065 220668.lp_2232 7.18e-153 429.0 COG0586@1|root,COG0586@2|Bacteria,1UZ4P@1239|Firmicutes,4HG3F@91061|Bacilli,3F4KG@33958|Lactobacillaceae 91061|Bacilli S SNARE-like domain protein dedA - - ko:K03975 - - - - ko00000 - - - SNARE_assoc GHFFDFOM_01066 220668.lp_2234 4.69e-151 424.0 COG4478@1|root,COG4478@2|Bacteria,1V7UW@1239|Firmicutes,4HHH4@91061|Bacilli,3F4YP@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1461) - - - - - - - - - - - - DUF1461 GHFFDFOM_01067 220668.lp_2235 7.18e-189 524.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,3F49D@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like GHFFDFOM_01068 220668.lp_2236 1.96e-116 337.0 COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli,3F66P@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1027) yutD - - - - - - - - - - - DUF1027 GHFFDFOM_01069 220668.lp_2237 0.0 940.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,3F4ZD@33958|Lactobacillaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos GHFFDFOM_01070 220668.lp_2238 5.77e-151 423.0 COG4186@1|root,COG4186@2|Bacteria,1V40Y@1239|Firmicutes,4HH4J@91061|Bacilli,3F4EX@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos,Metallophos_2 GHFFDFOM_01071 220668.lp_2240 0.0 874.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease cycA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease GHFFDFOM_01072 220668.lp_2242 4.7e-282 771.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase GHFFDFOM_01073 220668.lp_2243 1.56e-236 652.0 COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli,3F4CI@33958|Lactobacillaceae 91061|Bacilli L N-6 DNA Methylase ytxK - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase GHFFDFOM_01075 220668.lp_2244 6.46e-113 325.0 2DKN6@1|root,30A0S@2|Bacteria,1U61F@1239|Firmicutes,4IFQB@91061|Bacilli,3F6TY@33958|Lactobacillaceae 91061|Bacilli S Prokaryotic N-terminal methylation motif - - - - - - - - - - - - N_methyl GHFFDFOM_01076 60520.HR47_12770 3.03e-27 100.0 2A0ZU@1|root,30P57@2|Bacteria,1U8KD@1239|Firmicutes,4IIIC@91061|Bacilli,3FB2V@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - - GHFFDFOM_01077 220668.lp_2246 1.5e-108 312.0 COG2165@1|root,COG2165@2|Bacteria,1U5RV@1239|Firmicutes,4IFG1@91061|Bacilli,3F6E9@33958|Lactobacillaceae 91061|Bacilli NU general secretion pathway protein - - - ko:K02246 - M00429 - - ko00000,ko00002,ko02044 - - - - GHFFDFOM_01078 220668.lp_2247 1.97e-72 218.0 COG4537@1|root,COG4537@2|Bacteria,1VFI9@1239|Firmicutes,4HNNT@91061|Bacilli,3F7ZC@33958|Lactobacillaceae 91061|Bacilli U competence protein ComGC comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - ko:K02245 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl GHFFDFOM_01079 220668.lp_2248 6.2e-242 665.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,3F3S9@33958|Lactobacillaceae 91061|Bacilli NU type II secretion system comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF GHFFDFOM_01080 220668.lp_2249 1.55e-225 622.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,3F4HY@33958|Lactobacillaceae 91061|Bacilli NU Type II IV secretion system protein comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE GHFFDFOM_01081 220668.lp_2251 2.06e-205 570.0 COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HA87@91061|Bacilli,3F3S5@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB,Rib_5-P_isom_A GHFFDFOM_01082 220668.lp_2253 2.21e-168 471.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,3F4WF@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg GHFFDFOM_01083 220668.lp_2254 2.44e-65 199.0 COG1416@1|root,COG1416@2|Bacteria,1VEYT@1239|Firmicutes,4HP12@91061|Bacilli,3F7R7@33958|Lactobacillaceae 91061|Bacilli S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE GHFFDFOM_01084 220668.lp_2255 7.88e-211 582.0 COG1082@1|root,COG1082@2|Bacteria,1VSC9@1239|Firmicutes,4HUQI@91061|Bacilli,3F4RS@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 GHFFDFOM_01085 220668.lp_2256 5.44e-232 639.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,3F4AA@33958|Lactobacillaceae 91061|Bacilli K catabolite control protein A ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 GHFFDFOM_01086 220668.lp_2258 1.55e-275 752.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,3F3X5@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 GHFFDFOM_01087 220668.lp_2259 9.11e-106 305.0 COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4HH53@91061|Bacilli,3F5A9@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 GHFFDFOM_01088 220668.lp_2260 6.52e-96 281.0 2DKTG@1|root,30AR7@2|Bacteria,1U70A@1239|Firmicutes,4IGUM@91061|Bacilli,3F8T5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01089 220668.lp_2261 1.88e-75 227.0 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli,3F6KB@33958|Lactobacillaceae 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain ytxG - - - - - - - - - - - DUF948 GHFFDFOM_01090 220668.lp_2262 6.63e-202 560.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,3F49U@33958|Lactobacillaceae 91061|Bacilli M mechanosensitive ion channel ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K16052,ko:K22044 - - - - ko00000,ko02000 1.A.23.3,1.A.23.4 - - MS_channel GHFFDFOM_01091 220668.lp_2263 7.85e-288 785.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli,3F419@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 GHFFDFOM_01092 220668.lp_2264 2.29e-112 328.0 COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,3F3U0@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate dapH - 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14180 DapH_N,Hexapep GHFFDFOM_01093 220668.lp_2265 7.94e-114 326.0 COG0517@1|root,COG0517@2|Bacteria,1V9HN@1239|Firmicutes,4HH3X@91061|Bacilli,3F678@33958|Lactobacillaceae 91061|Bacilli S (CBS) domain ykuL - - - - - - - - - - - CBS GHFFDFOM_01094 220668.lp_2266 4.53e-122 348.0 COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli,3F73R@33958|Lactobacillaceae 91061|Bacilli S Phosphoesterase ysnB GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K07095 - - - - ko00000 - - - Metallophos_2 GHFFDFOM_01095 220668.lp_2267 3.46e-143 404.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,3F3KD@33958|Lactobacillaceae 91061|Bacilli F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like GHFFDFOM_01096 220668.lp_2268 8.74e-195 540.0 COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli,3F446@33958|Lactobacillaceae 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 - R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU28390 Asp_Glu_race GHFFDFOM_01097 220668.lp_2269 2.57e-118 340.0 COG1719@1|root,COG1719@2|Bacteria,1VD7N@1239|Firmicutes,4HKV3@91061|Bacilli,3F7ZI@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2507) yslB - - - - - - - - - - - DUF2507 GHFFDFOM_01098 220668.lp_2270 3e-69 209.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F6Y3@33958|Lactobacillaceae 91061|Bacilli O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin GHFFDFOM_01099 220668.lp_2271 0.0 1511.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,3F4DX@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr GHFFDFOM_01100 220668.lp_2272 1.06e-49 158.0 COG3027@1|root,COG3027@2|Bacteria,1VFZS@1239|Firmicutes,4HP4T@91061|Bacilli,3F7ZA@33958|Lactobacillaceae 91061|Bacilli D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division - - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA GHFFDFOM_01101 220668.lp_2273 1.31e-63 194.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli,3F6X3@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 GHFFDFOM_01102 220668.lp_2274 5.39e-96 280.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,3F6NI@33958|Lactobacillaceae 91061|Bacilli J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX GHFFDFOM_01103 220668.lp_2275 5e-57 177.0 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,3F7EG@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 GHFFDFOM_01104 220668.lp_2277 0.0 1738.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,3F3QS@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD GHFFDFOM_01105 220668.lp_2278 1.86e-316 862.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,3F4FQ@33958|Lactobacillaceae 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C GHFFDFOM_01106 220668.lp_2279 4.12e-227 625.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,3F4FC@33958|Lactobacillaceae 91061|Bacilli S DHHA1 domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 GHFFDFOM_01107 220668.lp_2280 2.48e-276 755.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,3F44N@33958|Lactobacillaceae 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH GHFFDFOM_01108 220668.lp_2281 1.32e-63 196.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,3F7EY@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC GHFFDFOM_01109 220668.lp_2282 9.91e-289 786.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,3F43F@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT GHFFDFOM_01110 220668.lp_2285 5.87e-256 701.0 COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,3F3VG@33958|Lactobacillaceae 91061|Bacilli J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth GHFFDFOM_01111 220668.lp_2286 2.62e-239 658.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,3F47S@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N GHFFDFOM_01112 220668.lp_2287 2.83e-138 391.0 COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli,3F42W@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N GHFFDFOM_01113 220668.lp_2289 2.07e-118 338.0 29NVQ@1|root,309TT@2|Bacteria,1U5PA@1239|Firmicutes,4IFDT@91061|Bacilli,3F69E@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01114 220668.lp_2290 0.0 1975.0 COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,4HD9X@91061|Bacilli,3F4AK@33958|Lactobacillaceae 91061|Bacilli S Bacterial membrane protein YfhO yfhO - - - - - - - - - - - YfhO GHFFDFOM_01115 220668.lp_2292 1.35e-93 273.0 29P6P@1|root,30A4T@2|Bacteria,1U674@1239|Firmicutes,4IFXQ@91061|Bacilli,3F78E@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01116 220668.lp_2297 0.0 1292.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,3F3PK@33958|Lactobacillaceae 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C GHFFDFOM_01117 220668.lp_2298 0.0 1677.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,3F4A5@33958|Lactobacillaceae 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V GHFFDFOM_01118 220668.lp_2299 6.18e-197 545.0 COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,4HAV5@91061|Bacilli,3F484@33958|Lactobacillaceae 91061|Bacilli S YmdB-like protein ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - ko:K02029,ko:K02030,ko:K09769 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - YmdB GHFFDFOM_01119 220668.lp_2300 6.57e-291 804.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,3F3WX@33958|Lactobacillaceae 91061|Bacilli S Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 GHFFDFOM_01120 220668.lp_2301 2.43e-264 725.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,3F3KU@33958|Lactobacillaceae 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA GHFFDFOM_01121 220668.lp_2302 1.56e-294 805.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,3F4I4@33958|Lactobacillaceae 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth GHFFDFOM_01122 220668.lp_2303 1.92e-127 363.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,3F4BI@33958|Lactobacillaceae 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf GHFFDFOM_01123 220668.lp_2304 5.74e-172 484.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,3F3SM@33958|Lactobacillaceae 91061|Bacilli S Helix-turn-helix domain ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 GHFFDFOM_01124 220668.lp_2305 0.0 864.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,3F4MU@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 ymfH - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C GHFFDFOM_01125 220668.lp_2306 7.16e-296 808.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,3F3SA@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 inactive domain protein ymfF - - - - - - - - - - - Peptidase_M16_C GHFFDFOM_01126 220668.lp_2308 0.0 884.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,3F48V@33958|Lactobacillaceae 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03790 AA_kinase,ACT,ACT_7 GHFFDFOM_01127 220668.lp_2312 2.61e-199 552.0 COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,4HF14@91061|Bacilli,3F3WC@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein aatB - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 GHFFDFOM_01128 220668.lp_2313 3.17e-149 420.0 COG1126@1|root,COG1126@2|Bacteria,1UYAZ@1239|Firmicutes,4HFTM@91061|Bacilli,3FC39@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran GHFFDFOM_01129 220668.lp_2314 1.89e-141 400.0 COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,4HGMH@91061|Bacilli,3F3VF@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease yecS_2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 GHFFDFOM_01130 220668.lp_2315 1.23e-187 521.0 COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,4HB2F@91061|Bacilli,3F3U8@33958|Lactobacillaceae 91061|Bacilli D Belongs to the ParA family minD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03609 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA GHFFDFOM_01131 220668.lp_2316 3.81e-150 423.0 COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,4HBTI@91061|Bacilli,3F61V@33958|Lactobacillaceae 91061|Bacilli D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization minC GO:0000910,GO:0003674,GO:0004857,GO:0007049,GO:0007105,GO:0008150,GO:0009987,GO:0022402,GO:0030234,GO:0031333,GO:0032271,GO:0032272,GO:0032506,GO:0043086,GO:0043254,GO:0044087,GO:0044092,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0065009,GO:0098772 - ko:K03610 - - - - ko00000,ko03036,ko04812 - - - MinC_C GHFFDFOM_01132 220668.lp_2317 9.47e-115 329.0 COG2891@1|root,COG2891@2|Bacteria,1VEV7@1239|Firmicutes,4HPAC@91061|Bacilli,3F6PG@33958|Lactobacillaceae 91061|Bacilli M rod shape-determining protein MreD mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD GHFFDFOM_01133 220668.lp_2318 3.76e-184 514.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,3F3MC@33958|Lactobacillaceae 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC GHFFDFOM_01134 220668.lp_2319 1.74e-211 587.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F3ZV@33958|Lactobacillaceae 91061|Bacilli D cell shape determining protein MreB mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl GHFFDFOM_01135 220668.lp_2320 1.15e-150 423.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,3F5IM@33958|Lactobacillaceae 91061|Bacilli L DNA repair protein radC - - ko:K03630 - - - - ko00000 - - - RadC GHFFDFOM_01136 220668.lp_2321 0.0 871.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,3F498@33958|Lactobacillaceae 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M GHFFDFOM_01137 220668.lp_2322 0.0 1785.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,3F3RB@33958|Lactobacillaceae 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 GHFFDFOM_01138 220668.lp_2323 3.56e-116 334.0 COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli,3F5VY@33958|Lactobacillaceae 91061|Bacilli O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - AhpC-TSA,Redoxin GHFFDFOM_01139 220668.lp_2324 5.71e-302 823.0 COG2918@1|root,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli,3F506@33958|Lactobacillaceae 91061|Bacilli H Belongs to the glutamate--cysteine ligase type 1 family gshF - 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ATP-grasp_3,Dala_Dala_lig_C,GARS_A,Glu_cys_ligase,RimK GHFFDFOM_01140 220668.lp_2325 7.66e-292 796.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,3F3N0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI GHFFDFOM_01141 220668.lp_2326 3.15e-278 760.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,3F4CD@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 GHFFDFOM_01143 220668.lp_2328 0.0 1073.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,3F47K@33958|Lactobacillaceae 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA GHFFDFOM_01144 220668.lp_2330 5.28e-105 303.0 COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli,3F6NT@33958|Lactobacillaceae 91061|Bacilli T GAF domain-containing protein yebR - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 GHFFDFOM_01145 220668.lp_2331 2.15e-137 389.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,3F3P0@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 GHFFDFOM_01146 220668.lp_2332 3.73e-150 422.0 COG4493@1|root,COG4493@2|Bacteria,1UY83@1239|Firmicutes,4HEDB@91061|Bacilli,3F62K@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0637 family yktB - - - - - - - - - - - DUF1054 GHFFDFOM_01147 220668.lp_2333 1.63e-104 302.0 COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HNNE@91061|Bacilli,3F64D@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1694) XK27_05190 - - - - - - - - - - - DUF1694 GHFFDFOM_01148 220668.lp_2334 1.57e-142 402.0 COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,4HK10@91061|Bacilli,3F4IE@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1648) - - - - - - - - - - - - DUF1648,SdpI GHFFDFOM_01149 220668.lp_2335 4.54e-59 182.0 COG0640@1|root,COG0640@2|Bacteria,1VA3M@1239|Firmicutes,4I4FT@91061|Bacilli,3F7BF@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 GHFFDFOM_01150 1123284.KB899046_gene2248 7.24e-291 808.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli 91061|Bacilli G COG0366 Glycosidases malL - 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C GHFFDFOM_01151 1423732.BALS01000065_gene2247 3.43e-55 176.0 COG2893@1|root,COG2893@2|Bacteria,1V7TP@1239|Firmicutes,4IQPD@91061|Bacilli,3F76S@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man GHFFDFOM_01152 411460.RUMTOR_00564 5.82e-139 400.0 COG3716@1|root,COG3716@2|Bacteria,1TSXA@1239|Firmicutes,25C3C@186801|Clostridia 186801|Clostridia G PTS system mannose fructose sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA GHFFDFOM_01153 1423734.JCM14202_2897 4.54e-132 381.0 COG3715@1|root,COG3715@2|Bacteria,1TSX0@1239|Firmicutes,4HBRB@91061|Bacilli,3F4X4@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor GHFFDFOM_01154 1423734.JCM14202_2898 3.79e-85 253.0 COG3444@1|root,COG3444@2|Bacteria,1V8BP@1239|Firmicutes,4HWNX@91061|Bacilli,3F6R3@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb GHFFDFOM_01155 1423734.JCM14202_2899 2.15e-118 352.0 COG1609@1|root,COG1609@2|Bacteria,1TRHK@1239|Firmicutes,4HB9P@91061|Bacilli,3F5FI@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding proteins and sugar binding domain of LacI family - - - - - - - - - - - - LacI,Peripla_BP_1,Peripla_BP_3 GHFFDFOM_01156 220668.lp_2336 0.0 1450.0 COG0189@1|root,COG2918@1|root,COG0189@2|Bacteria,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli,3F506@33958|Lactobacillaceae 91061|Bacilli H Belongs to the glutamate--cysteine ligase type 1 family gshAB - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase GHFFDFOM_01157 220668.lp_2337 7.27e-303 826.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3WF@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N GHFFDFOM_01158 220668.lp_2339 1.34e-52 166.0 2A52V@1|root,30TRA@2|Bacteria,1U68P@1239|Firmicutes,4IFZS@91061|Bacilli,3F7BD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01159 1136177.KCA1_1981 2.37e-107 310.0 COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli,3F68T@33958|Lactobacillaceae 91061|Bacilli T universal stress protein uspA - - - - - - - - - - - Usp GHFFDFOM_01160 220668.lp_2341 2.83e-261 717.0 COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,4HFV8@91061|Bacilli,3F5IH@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase enzyme family bla2 - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2,zinc_ribbon_2 GHFFDFOM_01161 220668.lp_2342 4.7e-207 573.0 COG1476@1|root,COG1476@2|Bacteria,1VMYH@1239|Firmicutes,4ISF0@91061|Bacilli,3F5QH@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3,TPR_8 GHFFDFOM_01162 220668.lp_2344 0.0 1026.0 COG0584@1|root,COG0584@2|Bacteria,1UG1C@1239|Firmicutes,4HCPQ@91061|Bacilli,3F5UQ@33958|Lactobacillaceae 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family glpQ3 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD GHFFDFOM_01163 220668.lp_2345 6.54e-273 746.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,3F41Z@33958|Lactobacillaceae 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N GHFFDFOM_01164 220668.lp_2346 7.55e-242 665.0 COG0604@1|root,COG0604@2|Bacteria,1TRNC@1239|Firmicutes,4HATC@91061|Bacilli,3F48F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily - - 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 GHFFDFOM_01165 220668.lp_2347 3.26e-227 626.0 29SNM@1|root,30DU7@2|Bacteria,1V3Z9@1239|Firmicutes,4HHKX@91061|Bacilli,3F3VM@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2785) - - - - - - - - - - - - DUF2785 GHFFDFOM_01166 220668.lp_2349 3.34e-215 594.0 COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli,3F4M2@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily hicD3 - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N GHFFDFOM_01167 220668.lp_2350 1.44e-189 527.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli,3FC6J@33958|Lactobacillaceae 91061|Bacilli M Belongs to the nlpA lipoprotein family metQ - - ko:K02072,ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 GHFFDFOM_01168 60520.HR47_13195 2.1e-151 427.0 COG2011@1|root,COG2011@2|Bacteria,1TR59@1239|Firmicutes,4H9NA@91061|Bacilli,3FC5J@33958|Lactobacillaceae 91061|Bacilli U ABC transporter permease metI GO:0000101,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015821,GO:0015849,GO:0016020,GO:0042940,GO:0044464,GO:0046942,GO:0048473,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072348 - ko:K02069,ko:K02072 ko02010,map02010 M00211,M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24,9.B.25.1 - - BPD_transp_1 GHFFDFOM_01169 220668.lp_2352 2.24e-239 659.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,3F3U5@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - iYO844.BSU32750 ABC_tran,NIL GHFFDFOM_01170 220668.lp_2353 3.2e-64 196.0 COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,3F7WB@33958|Lactobacillaceae 91061|Bacilli E glycine cleavage gcsH2 - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H GHFFDFOM_01171 220668.lp_2354 2.09e-279 765.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,3F4J4@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE GHFFDFOM_01172 220668.lp_2357 2.54e-46 149.0 2BQ47@1|root,302KN@2|Bacteria,1U6GB@1239|Firmicutes,4IG8F@91061|Bacilli,3F7UY@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2969) - - - - - - - - - - - - DUF2969 GHFFDFOM_01173 220668.lp_2358 1.52e-57 178.0 COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli,3F7H1@33958|Lactobacillaceae 91061|Bacilli S Could be involved in insertion of integral membrane proteins into the membrane ytjA - - ko:K08998 - - - - ko00000 - - - Haemolytic GHFFDFOM_01174 220668.lp_2359 1.44e-230 635.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F463@33958|Lactobacillaceae 91061|Bacilli D Cell shape determining protein MreB Mrl mbl - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl GHFFDFOM_01175 220668.lp_2360 1.68e-132 375.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,3FB7G@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain - - - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 GHFFDFOM_01176 220668.lp_2361 2.94e-315 858.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,3F3P8@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase GHFFDFOM_01177 220668.lp_2363 5.95e-74 224.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,3F6I6@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N GHFFDFOM_01178 220668.lp_2364 0.0 909.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,3F3TF@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N GHFFDFOM_01179 220668.lp_2365 2.15e-211 585.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,3F40E@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt GHFFDFOM_01180 220668.lp_2366 0.0 968.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,3F3R4@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N GHFFDFOM_01181 220668.lp_2367 2.03e-118 339.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKW1@91061|Bacilli,3FC7Z@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP GHFFDFOM_01182 1136177.KCA1_2003 5.41e-77 234.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,3F5M8@33958|Lactobacillaceae 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B GHFFDFOM_01183 1136177.KCA1_2004 1.81e-37 126.0 COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,4HNKQ@91061|Bacilli,3F82A@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C GHFFDFOM_01184 220668.lp_2370 4.82e-165 462.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,3F3RE@33958|Lactobacillaceae 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A GHFFDFOM_01185 220668.lp_2371 1.44e-293 803.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli,3F3UJ@33958|Lactobacillaceae 91061|Bacilli F Permease pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease GHFFDFOM_01186 1136177.KCA1_2007 7.81e-148 416.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,3F4M0@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase GHFFDFOM_01187 220668.lp_2375 3.04e-297 811.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,3F4C1@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT GHFFDFOM_01188 220668.lp_2376 2.09e-242 666.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,3F3T1@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC GHFFDFOM_01189 220668.lp_2377 3.44e-204 565.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,3F460@33958|Lactobacillaceae 91061|Bacilli J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS GHFFDFOM_01190 220668.lp_2378 1.88e-251 691.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,3F3Q0@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 GHFFDFOM_01191 220668.lp_2379 1.54e-141 399.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,3F4UE@33958|Lactobacillaceae 91061|Bacilli F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK GHFFDFOM_01192 220668.lp_2380 0.0 907.0 COG0770@1|root,COG0770@2|Bacteria,1TRG9@1239|Firmicutes,4HAMY@91061|Bacilli,3FBS5@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF1727) murE2 - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - DUF1727,Mur_ligase_M GHFFDFOM_01193 220668.lp_2382 1.06e-174 486.0 COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,4HD1P@91061|Bacilli,3F4CH@33958|Lactobacillaceae 91061|Bacilli S glutamine amidotransferase cobQ - - ko:K07009 - - - - ko00000 - - - GATase_3 GHFFDFOM_01194 220668.lp_2384 4.95e-250 684.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli,3F40I@33958|Lactobacillaceae 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI GHFFDFOM_01195 220668.lp_2385 3.09e-244 671.0 COG1680@1|root,COG1680@2|Bacteria,1TNZX@1239|Firmicutes,4IPJT@91061|Bacilli,3F3WZ@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase ampC - - - - - - - - - - - Beta-lactamase GHFFDFOM_01196 220668.lp_2388 2.1e-41 135.0 29PZR@1|root,30AY6@2|Bacteria,1U798@1239|Firmicutes,4IH44@91061|Bacilli,3F958@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01197 220668.lp_2390 3.15e-259 709.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli,3F4BD@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 GHFFDFOM_01198 220668.lp_2391 1.33e-77 230.0 2FI40@1|root,349WT@2|Bacteria,1W08C@1239|Firmicutes,4HYGC@91061|Bacilli,3F7QX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01199 220668.lp_2393 5.37e-182 512.0 2F31P@1|root,33VWT@2|Bacteria,1VWGD@1239|Firmicutes,4HWD9@91061|Bacilli,3F4CP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01200 220668.lp_2394 0.0 1206.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yfiC - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran GHFFDFOM_01201 220668.lp_2395 0.0 1073.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein ycfI - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran GHFFDFOM_01202 220668.lp_2396 5.63e-89 261.0 COG5294@1|root,COG5294@2|Bacteria,1VHCQ@1239|Firmicutes,4HNS8@91061|Bacilli,3F7UC@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) yxeA - - - - - - - - - - - DUF1093 GHFFDFOM_01203 220668.lp_2397 2.96e-182 509.0 COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,4HHC9@91061|Bacilli,3F5UZ@33958|Lactobacillaceae 91061|Bacilli G Polysaccharide deacetylase icaB - - - - - - - - - - - Polysacc_deac_1 GHFFDFOM_01206 220668.lp_2457 1.98e-40 133.0 29PK9@1|root,30AIF@2|Bacteria,1U6QM@1239|Firmicutes,4IGHW@91061|Bacilli,3F8B9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01208 220668.lp_2482 1.28e-51 162.0 2CH90@1|root,30ABZ@2|Bacteria,1U6G1@1239|Firmicutes,4IG82@91061|Bacilli,3F7U1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01209 220668.lp_2483 9.28e-58 179.0 2A6J2@1|root,30VCN@2|Bacteria,1U6I5@1239|Firmicutes,4IGAG@91061|Bacilli,3F7YQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01210 220668.lp_2484 1.27e-109 315.0 COG1846@1|root,COG1846@2|Bacteria,1U5IF@1239|Firmicutes,4IF98@91061|Bacilli,3F617@33958|Lactobacillaceae 91061|Bacilli K MarR family - - - - - - - - - - - - MarR_2 GHFFDFOM_01211 220668.lp_2485 0.0 1230.0 COG1196@1|root,COG1196@2|Bacteria,1U5DQ@1239|Firmicutes,4IF55@91061|Bacilli,3F5NM@33958|Lactobacillaceae 91061|Bacilli D nuclear chromosome segregation - - - - - - - - - - - - Glyco_trans_A_1 GHFFDFOM_01212 220668.lp_2486 0.0 1170.0 COG4932@1|root,COG4932@2|Bacteria,1UWF2@1239|Firmicutes,4HGU0@91061|Bacilli,3F6D1@33958|Lactobacillaceae 91061|Bacilli M MucBP domain inlJ - - - - - - - - - - - DUF285,Gram_pos_anchor,MucBP GHFFDFOM_01213 220668.lp_2488 6.58e-24 90.1 29QK0@1|root,32QG2@2|Bacteria,1U8FW@1239|Firmicutes,4IIDR@91061|Bacilli,3FAXW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01214 220668.lp_2488a 3.26e-24 90.9 29QK0@1|root,30AYF@2|Bacteria,1U79Q@1239|Firmicutes,4IH4K@91061|Bacilli,3F95V@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01215 220668.lp_2488 1.56e-22 86.7 29QK0@1|root,32QG2@2|Bacteria,1U8FW@1239|Firmicutes,4IIDR@91061|Bacilli,3FAXW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01216 220668.lp_2488c 1.07e-26 97.4 29QK0@1|root,30BJK@2|Bacteria,1U889@1239|Firmicutes,4II61@91061|Bacilli,3FAP0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01217 220668.lp_2488f 9.35e-24 89.7 29QK0@1|root,32P7Y@2|Bacteria,1U8G5@1239|Firmicutes,4IIDY@91061|Bacilli,3FAY3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01218 220668.lp_2488f 9.35e-24 89.7 29QK0@1|root,32P7Y@2|Bacteria,1U8G5@1239|Firmicutes,4IIDY@91061|Bacilli,3FAY3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01219 220668.lp_2488f 9.35e-24 89.7 29QK0@1|root,32P7Y@2|Bacteria,1U8G5@1239|Firmicutes,4IIDY@91061|Bacilli,3FAY3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01220 1136177.KCA1_2033 2.16e-26 96.7 29QK0@1|root,30BJK@2|Bacteria,1U889@1239|Firmicutes,4II61@91061|Bacilli,3FAP0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01221 220668.lp_2488h 4.63e-24 90.5 29QK0@1|root,30BIE@2|Bacteria,1U864@1239|Firmicutes,4II3N@91061|Bacilli,3FAKD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01222 220668.lp_2497 0.0 1077.0 COG1132@1|root,COG1132@2|Bacteria,1TSY4@1239|Firmicutes,4HAJQ@91061|Bacilli,3F5QW@33958|Lactobacillaceae 91061|Bacilli P ABC transporter transmembrane region - - 3.6.3.44 ko:K18104 ko01501,ko02010,map01501,map02010 M00700 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.117,3.A.1.123 - - ABC_membrane,ABC_tran GHFFDFOM_01223 220668.lp_2498 0.0 957.0 COG0438@1|root,COG0438@2|Bacteria,1V36G@1239|Firmicutes,4HJE7@91061|Bacilli,3FBE0@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 GHFFDFOM_01224 220668.lp_2499 0.0 1182.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F44P@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD GHFFDFOM_01225 60520.HR47_13790 2.1e-33 115.0 29QFN@1|root,30BF1@2|Bacteria,1U80S@1239|Firmicutes,4IHY6@91061|Bacilli,3FAE4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01226 220668.lp_2502 0.0 901.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli,3F3XK@33958|Lactobacillaceae 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI GHFFDFOM_01227 220668.lp_2503 2.51e-200 555.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,3F4K2@33958|Lactobacillaceae 91061|Bacilli U sugar transport glcU GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659 - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport GHFFDFOM_01228 220668.lp_2504 1.83e-277 759.0 COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,4HAA1@91061|Bacilli,3F49V@33958|Lactobacillaceae 91061|Bacilli J S-adenosylmethionine-dependent methyltransferase ywbD - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM GHFFDFOM_01229 220668.lp_2505 0.0 991.0 COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4IS6U@91061|Bacilli,3FBSR@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA GHFFDFOM_01230 220668.lp_2506 1.45e-173 484.0 COG0745@1|root,COG0745@2|Bacteria,1TQUQ@1239|Firmicutes,4HAXP@91061|Bacilli,3F3QZ@33958|Lactobacillaceae 91061|Bacilli K response regulator yclJ - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C GHFFDFOM_01231 220668.lp_2507 2.12e-308 842.0 COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,4HBTU@91061|Bacilli,3F4H2@33958|Lactobacillaceae 91061|Bacilli S UPF0210 protein XK27_08635 - - ko:K09157 - - - - ko00000 - - - DUF711 GHFFDFOM_01232 220668.lp_2508 3.04e-51 164.0 COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,4HNJ4@91061|Bacilli,3F811@33958|Lactobacillaceae 91061|Bacilli T Belongs to the UPF0237 family XK27_08630 - - ko:K07166 - - - - ko00000 - - - ACT_6 GHFFDFOM_01233 220668.lp_2509 1.26e-218 603.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F423@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA GHFFDFOM_01235 220668.lp_2512 6.24e-120 343.0 COG4720@1|root,COG4720@2|Bacteria,1VBHZ@1239|Firmicutes,4IR0C@91061|Bacilli,3FBKB@33958|Lactobacillaceae 91061|Bacilli S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS GHFFDFOM_01236 220668.lp_2513 1.31e-64 197.0 29PDQ@1|root,30ABW@2|Bacteria,1U6FW@1239|Firmicutes,4IG7V@91061|Bacilli,3F7TQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01237 220668.lp_2514 2.28e-272 746.0 COG0477@1|root,COG2814@2|Bacteria,1TQM0@1239|Firmicutes,4HATA@91061|Bacilli,3F3SE@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator yceI - - ko:K08369 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr GHFFDFOM_01238 220668.lp_2515 8.05e-178 495.0 COG1051@1|root,COG4111@1|root,COG1051@2|Bacteria,COG4111@2|Bacteria,1TST7@1239|Firmicutes,4HEFP@91061|Bacilli,3F54T@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX GHFFDFOM_01239 220668.lp_2516 2.68e-32 112.0 29PG1@1|root,30AE6@2|Bacteria,1U6IV@1239|Firmicutes,4IGB8@91061|Bacilli,3F805@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01241 220668.lp_2519 2.85e-71 221.0 COG4814@1|root,COG4814@2|Bacteria,1UY1T@1239|Firmicutes,4I2Y3@91061|Bacilli,3F5D8@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 GHFFDFOM_01242 220668.lp_2519 2.88e-113 330.0 COG4814@1|root,COG4814@2|Bacteria,1UY1T@1239|Firmicutes,4I2Y3@91061|Bacilli,3F5D8@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 GHFFDFOM_01243 220668.lp_2520 4.27e-223 613.0 COG0791@1|root,COG0791@2|Bacteria,1TSZ0@1239|Firmicutes,4HBUM@91061|Bacilli,3F5GI@33958|Lactobacillaceae 91061|Bacilli M NlpC/P60 family ykfC - 3.4.14.13 ko:K20742 - - - - ko00000,ko01000,ko01002 - - - NLPC_P60 GHFFDFOM_01244 220668.lp_2521 4.17e-107 308.0 COG1522@1|root,COG1522@2|Bacteria,1V3MI@1239|Firmicutes,4HJUY@91061|Bacilli,3F6FN@33958|Lactobacillaceae 91061|Bacilli K AsnC family - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type GHFFDFOM_01245 220668.lp_2522 2.29e-48 154.0 29PPI@1|root,30AMP@2|Bacteria,1U6VE@1239|Firmicutes,4IGPB@91061|Bacilli,3F8JQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01246 220668.lp_2523 1.11e-45 147.0 29PG2@1|root,30AE7@2|Bacteria,1U6IW@1239|Firmicutes,4IGBE@91061|Bacilli,3F80G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01247 220668.lp_2524 8.05e-278 760.0 COG2199@1|root,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,4HBT1@91061|Bacilli,3F4R9@33958|Lactobacillaceae 91061|Bacilli T diguanylate cyclase - - - - - - - - - - - - GGDEF,Hpt,Response_reg GHFFDFOM_01248 220668.lp_2525 0.0 1019.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,3F3QI@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn GHFFDFOM_01249 220668.lp_2526 9.24e-140 394.0 COG0454@1|root,COG0456@2|Bacteria,1V7GR@1239|Firmicutes,4HJ11@91061|Bacilli,3F44B@33958|Lactobacillaceae 91061|Bacilli K acetyltransferase - - - ko:K06977 - - - - ko00000 - - - Acetyltransf_1 GHFFDFOM_01250 220668.lp_2528 1.16e-106 307.0 COG0346@1|root,COG0346@2|Bacteria,1V7D7@1239|Firmicutes,4HIGP@91061|Bacilli,3F6XZ@33958|Lactobacillaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase,NUDIX GHFFDFOM_01251 220668.lp_2529 9.2e-62 191.0 29Q78@1|root,30B69@2|Bacteria,1U7MB@1239|Firmicutes,4IHIG@91061|Bacilli,3F9WG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01252 220668.lp_2531 0.0 1247.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,3F44V@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system, EIIB nagE - 2.7.1.193,2.7.1.199,2.7.1.208 ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00267,M00268,M00270,M00272,M00303,M00806,M00809 R02738,R02780,R04111,R04394,R05132,R05199,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9 - iSB619.SA_RS08720 PTS_EIIA_1,PTS_EIIB,PTS_EIIC GHFFDFOM_01253 220668.lp_2532 4.37e-241 661.0 COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,4HB4T@91061|Bacilli,3F455@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE1 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C GHFFDFOM_01254 220668.lp_2534 5.97e-210 580.0 COG1307@1|root,COG1307@2|Bacteria,1VUI4@1239|Firmicutes,4HVVF@91061|Bacilli,3F5VF@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 - - - - - - - - - - - - DegV GHFFDFOM_01255 220668.lp_2535 4.12e-293 801.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,3F3KS@33958|Lactobacillaceae 91061|Bacilli E Homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 GHFFDFOM_01256 220668.lp_2536 2.48e-311 848.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,4H9X5@91061|Bacilli,3FBSS@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol metY - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP GHFFDFOM_01257 220668.lp_2537 1.26e-212 587.0 COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli,3F5CA@33958|Lactobacillaceae 91061|Bacilli E Transfers an acetyl group from acetyl-CoA to metAA - 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS GHFFDFOM_01258 220668.lp_2541 2.79e-226 625.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F462@33958|Lactobacillaceae 91061|Bacilli S ABC transporter ABC-SBP - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind GHFFDFOM_01259 220668.lp_2542 6.03e-196 545.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,3F40J@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family XK27_08840 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 GHFFDFOM_01260 220668.lp_2543 1.38e-180 503.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,3F3NW@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein XK27_08845 - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran GHFFDFOM_01261 220668.lp_2544 0.0 892.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase npr - 1.11.1.1 ko:K05910 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim GHFFDFOM_01262 220668.lp_2548 6.42e-201 556.0 COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,3F3XC@33958|Lactobacillaceae 91061|Bacilli I Dehydrogenase glxR - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 GHFFDFOM_01263 220668.lp_2549 5.83e-176 491.0 COG0861@1|root,COG0861@2|Bacteria,1UVIJ@1239|Firmicutes,4HEKW@91061|Bacilli,3F3WS@33958|Lactobacillaceae 91061|Bacilli P membrane yceF - - ko:K05794 - - - - ko00000 - - - TerC GHFFDFOM_01264 220668.lp_2550 2.28e-121 347.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4IPXR@91061|Bacilli,3FBEK@33958|Lactobacillaceae 91061|Bacilli S Maltose acetyltransferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac GHFFDFOM_01265 220668.lp_2551 2.9e-253 695.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,3F466@33958|Lactobacillaceae 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GHFFDFOM_01266 220668.lp_2552 4.37e-68 206.0 COG0140@1|root,COG0140@2|Bacteria,1VB6S@1239|Firmicutes,4HKDY@91061|Bacilli,3F7V5@33958|Lactobacillaceae 91061|Bacilli E phosphoribosyl-ATP diphosphatase activity hisE - 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH GHFFDFOM_01267 220668.lp_2553 2.49e-77 229.0 COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,3F73W@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH GHFFDFOM_01268 220668.lp_2554 1.27e-172 482.0 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli,3F3XV@33958|Lactobacillaceae 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14115 His_biosynth GHFFDFOM_01269 220668.lp_2556 6.84e-166 464.0 COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli,3F5YT@33958|Lactobacillaceae 91061|Bacilli E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth GHFFDFOM_01270 220668.lp_2557 2.23e-142 402.0 COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HHNQ@91061|Bacilli,3F5AD@33958|Lactobacillaceae 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase GHFFDFOM_01271 220668.lp_2558 1.42e-138 391.0 COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4HCFG@91061|Bacilli,3F4TQ@33958|Lactobacillaceae 91061|Bacilli E imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14130 IGPD GHFFDFOM_01272 220668.lp_2559 1.83e-297 813.0 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,3F40P@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU34910 Histidinol_dh GHFFDFOM_01273 220668.lp_2560 1.69e-151 426.0 COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli,3F4WT@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,tRNA-synt_His GHFFDFOM_01274 220668.lp_2561 7.68e-274 749.0 COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli,3F4W1@33958|Lactobacillaceae 91061|Bacilli E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His GHFFDFOM_01275 220668.lp_2563 3.05e-205 566.0 COG1387@1|root,COG1387@2|Bacteria,1TQQX@1239|Firmicutes,4H9P1@91061|Bacilli,3F4WG@33958|Lactobacillaceae 91061|Bacilli E Histidinol phosphate phosphatase, HisJ hisK - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PHP,PHP_C GHFFDFOM_01276 220668.lp_2564 1.77e-281 769.0 COG4767@1|root,COG4767@2|Bacteria,1V04Y@1239|Firmicutes,4HDS5@91061|Bacilli,3F3SH@33958|Lactobacillaceae 91061|Bacilli V RDD family ysaA - - - - - - - - - - - RDD,VanZ GHFFDFOM_01277 220668.lp_2565 7.28e-213 588.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli,3F4B8@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA GHFFDFOM_01278 220668.lp_2566 6.7e-74 221.0 COG5646@1|root,COG5646@2|Bacteria,1U6GV@1239|Firmicutes,4IG91@91061|Bacilli,3F7W5@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 GHFFDFOM_01279 220668.lp_2567 4.73e-118 337.0 COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4HH53@91061|Bacilli,3F69R@33958|Lactobacillaceae 91061|Bacilli K transcriptional regulator, MerR family rmeB - - - - - - - - - - - MerR_1 GHFFDFOM_01280 220668.lp_2568 2.49e-190 529.0 COG4221@1|root,COG4221@2|Bacteria,1TQDY@1239|Firmicutes,4HEWY@91061|Bacilli,3F51P@33958|Lactobacillaceae 91061|Bacilli GM Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short GHFFDFOM_01281 220668.lp_2569 4.54e-126 358.0 COG3832@1|root,COG3832@2|Bacteria,1V6JA@1239|Firmicutes,4IFEJ@91061|Bacilli,3F6B6@33958|Lactobacillaceae 91061|Bacilli J glyoxalase III activity - - - - - - - - - - - - - GHFFDFOM_01282 220668.lp_2570 1.69e-255 700.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,3F4S9@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC GHFFDFOM_01283 220668.lp_2572 5.72e-238 653.0 COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,4HEQ3@91061|Bacilli,3F3RA@33958|Lactobacillaceae 91061|Bacilli M Linear amide C-N hydrolase, choloylglycine hydrolase family protein yxeI - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH GHFFDFOM_01284 220668.lp_2573 1.45e-46 149.0 2A2W9@1|root,30RAC@2|Bacteria,1U6AC@1239|Firmicutes,4IG1N@91061|Bacilli,3F7FP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01285 220668.lp_2574 3.1e-144 409.0 COG3548@1|root,COG3548@2|Bacteria,1U544@1239|Firmicutes,4IEVF@91061|Bacilli,3F4HQ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 GHFFDFOM_01286 220668.lp_2575 0.0 1623.0 COG2409@1|root,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4HBM6@91061|Bacilli,3FCCY@33958|Lactobacillaceae 91061|Bacilli S MMPL family ydgH - - ko:K06994 - - - - ko00000 - - - MMPL GHFFDFOM_01287 220668.lp_2578 0.0 915.0 COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,3F4FM@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - Cna_B,Collagen_bind,Gram_pos_anchor,MucBP GHFFDFOM_01288 220668.lp_2578 2.29e-30 118.0 COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,3F4FM@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - Cna_B,Collagen_bind,Gram_pos_anchor,MucBP GHFFDFOM_01289 220668.lp_2579 7.35e-99 287.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli,3F6HQ@33958|Lactobacillaceae 91061|Bacilli S Acetyltransferase (GNAT) domain yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 GHFFDFOM_01290 220668.lp_2580 0.0 1389.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase GHFFDFOM_01291 220668.lp_2582 0.0 1111.0 COG0584@1|root,COG4781@1|root,COG0584@2|Bacteria,COG4781@2|Bacteria,1UG1C@1239|Firmicutes,4HCPQ@91061|Bacilli,3F3SZ@33958|Lactobacillaceae 91061|Bacilli C phosphodiesterase glpQ4 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,GPDPase_memb GHFFDFOM_01292 220668.lp_2585 4.01e-236 649.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,3F3NQ@33958|Lactobacillaceae 91061|Bacilli C Ferredoxin--NADP reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 GHFFDFOM_01293 220668.lp_2586 2.14e-183 509.0 COG4814@1|root,COG4814@2|Bacteria,1VXHZ@1239|Firmicutes,4HX59@91061|Bacilli,3F75V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 GHFFDFOM_01294 220668.lp_2588 7.24e-250 704.0 COG3827@1|root,COG3827@2|Bacteria,1UIXJ@1239|Firmicutes,4I0W9@91061|Bacilli,3F6DZ@33958|Lactobacillaceae 91061|Bacilli S domain, Protein - - - - - - - - - - - - - GHFFDFOM_01295 220668.lp_2589 6.04e-217 598.0 COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,4HHU5@91061|Bacilli,3FBA4@33958|Lactobacillaceae 91061|Bacilli S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 GHFFDFOM_01296 220668.lp_2590 2.57e-128 365.0 COG0778@1|root,COG0778@2|Bacteria,1UYJU@1239|Firmicutes,4HBVQ@91061|Bacilli,3F5ZD@33958|Lactobacillaceae 91061|Bacilli C Nitroreductase family - - - - - - - - - - - - Nitroreductase GHFFDFOM_01297 220668.lp_2591 1.23e-228 629.0 COG1957@1|root,COG1957@2|Bacteria,1TSAR@1239|Firmicutes,4HDCS@91061|Bacilli,3F4A3@33958|Lactobacillaceae 91061|Bacilli F nucleoside hydrolase iunH1 - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro GHFFDFOM_01298 220668.lp_2593 1.03e-210 582.0 COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1V4A0@1239|Firmicutes,4HHJ9@91061|Bacilli,3F3RG@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - Cauli_VI,RNase_H GHFFDFOM_01299 220668.lp_2594 8.1e-200 553.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,3F4K2@33958|Lactobacillaceae 91061|Bacilli U sugar transport - - - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport GHFFDFOM_01300 220668.lp_2595 3.16e-232 639.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,4HE30@91061|Bacilli,3F3ZI@33958|Lactobacillaceae 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK GHFFDFOM_01301 220668.lp_2596 2.08e-199 551.0 COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,4HACV@91061|Bacilli,3F472@33958|Lactobacillaceae 91061|Bacilli C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM GHFFDFOM_01302 220668.lp_2597 2.48e-174 486.0 COG1349@1|root,COG1349@2|Bacteria,1TNYH@1239|Firmicutes,4HC6X@91061|Bacilli,3F5M5@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain rdrA - - ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR GHFFDFOM_01303 220668.lp_2598 0.0 1642.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,4HATB@91061|Bacilli,3FCBM@33958|Lactobacillaceae 91061|Bacilli C Pyruvate formate lyase-like pflD - 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like GHFFDFOM_01304 220668.lp_2599 4.3e-228 628.0 COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,4HCAR@91061|Bacilli,3F4PP@33958|Lactobacillaceae 91061|Bacilli K sugar-binding domain protein - - - - - - - - - - - - HTH_23,HTH_24,HTH_Crp_2,Sugar-bind GHFFDFOM_01305 220668.lp_2600 1.81e-160 450.0 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,4HA8G@91061|Bacilli,3F4Q8@33958|Lactobacillaceae 91061|Bacilli H Transaldolase/Fructose-6-phosphate aldolase mipB - 2.2.1.2 ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA GHFFDFOM_01306 220668.lp_2601 2.13e-182 507.0 COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,3F4XA@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 GHFFDFOM_01307 220668.lp_2602 2.89e-224 618.0 COG1609@1|root,COG1609@2|Bacteria,1TQSQ@1239|Firmicutes,4HBNR@91061|Bacilli,3F4YI@33958|Lactobacillaceae 91061|Bacilli K lacI family ccpB - - - - - - - - - - - LacI,Peripla_BP_1 GHFFDFOM_01308 220668.lp_2603 6.43e-204 564.0 COG1737@1|root,COG1737@2|Bacteria,1V5GV@1239|Firmicutes,4HHPG@91061|Bacilli,3F5EG@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS GHFFDFOM_01309 220668.lp_2604 3.02e-228 629.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HDXF@91061|Bacilli,3FCE8@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C GHFFDFOM_01310 220668.lp_2606 1.89e-254 696.0 COG0673@1|root,COG0673@2|Bacteria,1TR8S@1239|Firmicutes,4HBHI@91061|Bacilli,3F4QU@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain yhhX - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C GHFFDFOM_01311 220668.lp_2608 0.0 1204.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter nhaP2 - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger GHFFDFOM_01312 220668.lp_2610 0.0 1153.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,3F4RN@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C GHFFDFOM_01313 220668.lp_2612 9.38e-139 391.0 COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli,3F41F@33958|Lactobacillaceae 91061|Bacilli Q Isochorismatase family pncA - - - - - - - - - - - Isochorismatase GHFFDFOM_01314 220668.lp_2613 1.54e-171 480.0 29NT4@1|root,309R6@2|Bacteria,1U5IX@1239|Firmicutes,4HZ1H@91061|Bacilli,3F624@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01315 220668.lp_2614 5e-162 454.0 COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,4HGHM@91061|Bacilli,3FC3H@33958|Lactobacillaceae 91061|Bacilli V ABC transporter skfE - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_01316 220668.lp_2615 2.39e-85 251.0 COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,4HPK4@91061|Bacilli,3F6GC@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, GntR family lexA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR GHFFDFOM_01317 220668.lp_2616 2.07e-60 186.0 2CK4C@1|root,30266@2|Bacteria,1U669@1239|Firmicutes,4IFWF@91061|Bacilli,3F764@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun GHFFDFOM_01318 220668.lp_2620 3.25e-223 615.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta ybcH - - ko:K06889 - - - - ko00000 - - - DLH,Hydrolase_4 GHFFDFOM_01319 220668.lp_2621 1.76e-88 276.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,3F4ZV@33958|Lactobacillaceae 91061|Bacilli E Oligopeptidase F pepF2 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N GHFFDFOM_01320 220668.lp_2621 0.0 920.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,3F4ZV@33958|Lactobacillaceae 91061|Bacilli E Oligopeptidase F pepF2 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N GHFFDFOM_01321 220668.lp_2622 1.4e-95 278.0 COG1396@1|root,COG1396@2|Bacteria,1VEC4@1239|Firmicutes,4HM2F@91061|Bacilli,3F654@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_3 GHFFDFOM_01322 220668.lp_2623 2.64e-210 580.0 2E39Q@1|root,32Y99@2|Bacteria,1VQQ8@1239|Firmicutes,4HRY1@91061|Bacilli,3F4UX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01324 220668.lp_2624 2.49e-75 225.0 29PD5@1|root,30ABC@2|Bacteria,1U6FB@1239|Firmicutes,4IG76@91061|Bacilli,3F7SH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01325 220668.lp_2625 2.8e-63 193.0 2AXGE@1|root,31PG2@2|Bacteria,1U83C@1239|Firmicutes,4II0S@91061|Bacilli,3FAH7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01326 220668.lp_2629 0.0 1145.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family spxB - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GHFFDFOM_01327 220668.lp_2630 1.17e-88 260.0 29P52@1|root,30A39@2|Bacteria,1U64R@1239|Firmicutes,4IFUA@91061|Bacilli,3F71Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01328 220668.lp_2631 1.19e-186 518.0 COG1073@1|root,COG1073@2|Bacteria,1TTC0@1239|Firmicutes,4IBNH@91061|Bacilli,3F3XJ@33958|Lactobacillaceae 91061|Bacilli S Dienelactone hydrolase family - - - ko:K06889 - - - - ko00000 - - - DLH,Peptidase_S9 GHFFDFOM_01329 220668.lp_2633 9.89e-74 220.0 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,3F72K@33958|Lactobacillaceae 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin GHFFDFOM_01330 220668.lp_2634 3.87e-262 719.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,3F4CK@33958|Lactobacillaceae 91061|Bacilli E Cys/Met metabolism PLP-dependent enzyme metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP GHFFDFOM_01331 220668.lp_2635 3.89e-62 191.0 29P3W@1|root,30A23@2|Bacteria,1U637@1239|Firmicutes,4IFSI@91061|Bacilli,3F6XJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01332 220668.lp_2636 1.57e-71 224.0 29NVK@1|root,309TP@2|Bacteria,1U5NY@1239|Firmicutes,4IFDG@91061|Bacilli,3F68R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01333 220668.lp_2638 6.94e-106 306.0 2BWFV@1|root,32QWV@2|Bacteria,1UPWN@1239|Firmicutes,4HXPC@91061|Bacilli,3F59W@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2798) - - - - - - - - - - - - DUF2798 GHFFDFOM_01334 220668.lp_2641 4.05e-98 285.0 29V33@1|root,30GGE@2|Bacteria,1UFZH@1239|Firmicutes,4IF1H@91061|Bacilli,3F5BQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01335 220668.lp_2642 4.15e-78 233.0 29P7Q@1|root,309XV@2|Bacteria,1U5WQ@1239|Firmicutes,4IFK6@91061|Bacilli,3F6MJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01336 220668.lp_2643 4.26e-250 685.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,3F4UZ@33958|Lactobacillaceae 91061|Bacilli H Lipoate-protein ligase lplA - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C GHFFDFOM_01337 220668.lp_2645 0.0 1261.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIVW@91061|Bacilli,3FC1A@33958|Lactobacillaceae 91061|Bacilli NU Bacterial SH3 domain acm2 - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Glucosaminidase,Prophage_tail,SH3_5 GHFFDFOM_01338 220668.lp_2652 1.02e-102 297.0 COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,4HNHG@91061|Bacilli,3F4Z0@33958|Lactobacillaceae 91061|Bacilli T universal stress protein uspA3 - - - - - - - - - - - Usp GHFFDFOM_01339 220668.lp_2653 1.02e-202 562.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli,3F50K@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 GHFFDFOM_01340 1423806.JCM15457_1791 2.73e-24 107.0 2DKSD@1|root,30AMG@2|Bacteria,1U6V5@1239|Firmicutes,4IGP1@91061|Bacilli,3F8J7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01341 1136177.KCA1_2165 1.09e-55 188.0 COG4640@1|root,COG4640@2|Bacteria,1VIMB@1239|Firmicutes,4HP7R@91061|Bacilli,3F7Z9@33958|Lactobacillaceae 91061|Bacilli S zinc-ribbon domain - - - - - - - - - - - - zf-ribbon_3,zinc_ribbon_2 GHFFDFOM_01342 1136177.KCA1_2168 1.2e-97 301.0 COG4640@1|root,COG4640@2|Bacteria,1UYJN@1239|Firmicutes,4HF8I@91061|Bacilli,3FBEE@33958|Lactobacillaceae 91061|Bacilli S response to antibiotic tcaA - - ko:K21463 - - - - ko00000 - - - zf-ribbon_3,zinc_ribbon_2 GHFFDFOM_01343 220668.lp_2654 4.05e-64 196.0 COG1396@1|root,COG1396@2|Bacteria,1V3D7@1239|Firmicutes,4IGD5@91061|Bacilli,3F83A@33958|Lactobacillaceae 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 GHFFDFOM_01344 60520.HR47_14325 1.38e-30 108.0 29QG6@1|root,30BFM@2|Bacteria,1U81Q@1239|Firmicutes,4IHZ3@91061|Bacilli,3FAF3@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2929) - - - - - - - - - - - - DUF2929 GHFFDFOM_01345 220668.lp_2658 5.31e-285 778.0 COG0438@1|root,COG0438@2|Bacteria,1TPHK@1239|Firmicutes,4HAXV@91061|Bacilli,3F5EZ@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 GHFFDFOM_01346 220668.lp_2659 0.0 1628.0 COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,4HC2J@91061|Bacilli,3F3TZ@33958|Lactobacillaceae 91061|Bacilli G Phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N GHFFDFOM_01347 220668.lp_2660 6.26e-213 587.0 COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,4HD64@91061|Bacilli,3F57H@33958|Lactobacillaceae 91061|Bacilli S Putative esterase - - - - - - - - - - - - Esterase GHFFDFOM_01348 220668.lp_2661 3.53e-169 473.0 COG2188@1|root,COG2188@2|Bacteria,1V0UW@1239|Firmicutes,4IPQ0@91061|Bacilli,3FBE1@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - GntR,UTRA GHFFDFOM_01349 220668.lp_2662 4.75e-117 335.0 COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HHVB@91061|Bacilli,3F5H1@33958|Lactobacillaceae 91061|Bacilli S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ybaK - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit GHFFDFOM_01350 220668.lp_2663 1.74e-178 498.0 arCOG05209@1|root,31PIN@2|Bacteria,1V5G2@1239|Firmicutes,4HIRV@91061|Bacilli,3F6X9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01351 220668.lp_2664 1.97e-150 423.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,3F3PN@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. yagB - - ko:K06950 - - - - ko00000 - - - HD GHFFDFOM_01352 220668.lp_2665 8.05e-179 498.0 COG3279@1|root,COG3279@2|Bacteria,1U5HV@1239|Firmicutes,4IF8N@91061|Bacilli,3F5ZC@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain rrp8 - - - - - - - - - - - LytTR,Response_reg GHFFDFOM_01353 220668.lp_2666 1.7e-118 339.0 COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes,4HJXK@91061|Bacilli,3F5IX@33958|Lactobacillaceae 91061|Bacilli K Domain of unknown function (DUF1836) - - - - - - - - - - - - DUF1836 GHFFDFOM_01354 220668.lp_2667 6.31e-79 234.0 2CICD@1|root,3462T@2|Bacteria,1VZWZ@1239|Firmicutes,4HY4B@91061|Bacilli,3F6T8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01355 220668.lp_2668 2.61e-96 280.0 COG0071@1|root,COG0071@2|Bacteria,1U5MK@1239|Firmicutes,4IFCD@91061|Bacilli,3F677@33958|Lactobacillaceae 91061|Bacilli O Belongs to the small heat shock protein (HSP20) family hsp2 - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 GHFFDFOM_01356 220668.lp_2669 2.97e-76 227.0 29PHG@1|root,30AFM@2|Bacteria,1U6KN@1239|Firmicutes,4IGDE@91061|Bacilli,3F83U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01357 220668.lp_2671 0.0 868.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,3F3TX@33958|Lactobacillaceae 91061|Bacilli S Transporter associated domain yhdP - - - - - - - - - - - CBS,CorC_HlyC,DUF21 GHFFDFOM_01358 220668.lp_2673 1.18e-114 328.0 COG1780@1|root,COG1780@2|Bacteria,1V71V@1239|Firmicutes,4HIW7@91061|Bacilli,3F6JF@33958|Lactobacillaceae 91061|Bacilli F Belongs to the NrdI family nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI GHFFDFOM_01359 220668.lp_2674 0.0 958.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter nhaP3 - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger GHFFDFOM_01360 220668.lp_2675 1.17e-270 741.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,3F4F9@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator yttB - - - - - - - - - - - MFS_1 GHFFDFOM_01361 220668.lp_2676 2.84e-82 243.0 COG0789@1|root,COG0789@2|Bacteria,1U7JK@1239|Firmicutes,4IHGP@91061|Bacilli,3F9TS@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 GHFFDFOM_01362 220668.lp_2677 1.27e-219 606.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4I2RV@91061|Bacilli,3F9BC@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 GHFFDFOM_01363 220668.lp_2680 4.71e-74 222.0 29F74@1|root,3024T@2|Bacteria,1U64W@1239|Firmicutes,4IFUM@91061|Bacilli,3F720@33958|Lactobacillaceae 91061|Bacilli S SdpI/YhfL protein family - - - - - - - - - - - - SdpI GHFFDFOM_01364 220668.lp_2681 0.0 1017.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,3F48G@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N GHFFDFOM_01365 220668.lp_2683 0.0 895.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB2U@91061|Bacilli,3F5UY@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, gntR family gabR - - ko:K00375 - - - - ko00000,ko03000 - - - Aminotran_1_2,GntR GHFFDFOM_01366 220668.lp_2684 4.83e-276 755.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase araT2 - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GHFFDFOM_01367 220668.lp_2685 1.84e-204 566.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,3F4UH@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS GHFFDFOM_01368 1114972.AUAW01000027_gene735 3.59e-26 95.9 29QNC@1|root,30BN0@2|Bacteria,1U8CI@1239|Firmicutes,4IIAH@91061|Bacilli,3FAU7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01369 220668.lp_2688 2.09e-169 474.0 COG0730@1|root,COG0730@2|Bacteria,1VR9G@1239|Firmicutes,4HV4W@91061|Bacilli,3F3TR@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE GHFFDFOM_01370 220668.lp_2689 5.73e-208 575.0 COG0583@1|root,COG0583@2|Bacteria,1V5VW@1239|Firmicutes,4HHDY@91061|Bacilli,3F5D2@33958|Lactobacillaceae 91061|Bacilli K LysR family mleR - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_01371 220668.lp_2690 1.29e-148 418.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,3F521@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10 GHFFDFOM_01372 220668.lp_2691 3.86e-124 353.0 COG0454@1|root,COG0456@2|Bacteria,1V6Z8@1239|Firmicutes,4HMP7@91061|Bacilli,3F6WQ@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 GHFFDFOM_01373 220668.lp_2693 0.0 2405.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,3F3Z0@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C GHFFDFOM_01374 220668.lp_2694 0.0 2371.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,3F3RS@33958|Lactobacillaceae 91061|Bacilli L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C GHFFDFOM_01375 60520.HR47_14480 4.54e-216 598.0 COG3238@1|root,COG3238@2|Bacteria,1V0FB@1239|Firmicutes,4HFG7@91061|Bacilli,3F4R4@33958|Lactobacillaceae 91061|Bacilli S Putative inner membrane exporter, YdcZ oroP - - ko:K09936 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.7.21 - - DMT_YdcZ GHFFDFOM_01376 220668.lp_2697 6.64e-146 411.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,3F487@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15560 Pribosyltran GHFFDFOM_01377 220668.lp_2698 1.09e-161 453.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli,3F47Y@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase GHFFDFOM_01378 220668.lp_2699 1.04e-218 603.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,3F4PJ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh GHFFDFOM_01379 60520.HR47_14500 0.0 2048.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS GHFFDFOM_01380 220668.lp_2701 3.36e-272 743.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,3F43R@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase GHFFDFOM_01381 220668.lp_2702 2.38e-310 845.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,3F3S3@33958|Lactobacillaceae 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 GHFFDFOM_01382 220668.lp_2703 1.22e-220 608.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli,3F4BQ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N GHFFDFOM_01383 1136177.KCA1_2211 7.13e-123 350.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,3F4SR@33958|Lactobacillaceae 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran GHFFDFOM_01384 220668.lp_2708 0.0 1026.0 COG2508@1|root,COG2508@2|Bacteria,1TRDF@1239|Firmicutes,4H9KC@91061|Bacilli,3F5A2@33958|Lactobacillaceae 91061|Bacilli QT Purine catabolism regulatory protein-like family pucR_2 - - ko:K09684 - - - - ko00000,ko03000 - - - HTH_30,PucR GHFFDFOM_01385 220668.lp_2710 3.1e-305 834.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,3F3Y7@33958|Lactobacillaceae 91061|Bacilli F xanthine permease pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K03458,ko:K16169 - - - - ko00000,ko02000 2.A.40,2.A.40.3.1 - iSB619.SA_RS02140 Xan_ur_permease GHFFDFOM_01386 220668.lp_2712 5.67e-280 768.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,3F4QP@33958|Lactobacillaceae 91061|Bacilli S Permease family pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - iYO844.BSU06370 Xan_ur_permease GHFFDFOM_01387 220668.lp_2713 2.24e-206 572.0 COG0702@1|root,COG0702@2|Bacteria,1V9EI@1239|Firmicutes,4HJCA@91061|Bacilli,3F607@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10,NmrA GHFFDFOM_01388 220668.lp_2714 1.25e-199 552.0 COG2200@1|root,COG2200@2|Bacteria,1VM9X@1239|Firmicutes,4IF18@91061|Bacilli,3F5AS@33958|Lactobacillaceae 91061|Bacilli T EAL domain - - - - - - - - - - - - EAL GHFFDFOM_01389 220668.lp_2715 2.62e-121 346.0 2E4JE@1|root,32ZEG@2|Bacteria,1VG2N@1239|Firmicutes,4HPPN@91061|Bacilli,3F6QS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01390 220668.lp_2716 0.0 874.0 COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,3F3RY@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase yijG - - ko:K11936 ko02026,map02026 - - - ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.2,4.D.1.1.3 GT2 - Glyco_tranf_2_3,Glycos_transf_2 GHFFDFOM_01391 220668.lp_2718 3.85e-159 446.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,3F6F6@33958|Lactobacillaceae 91061|Bacilli E Methionine synthase - - - - - - - - - - - - Meth_synt_2 GHFFDFOM_01392 220668.lp_2719 2.71e-280 768.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,3F4Z8@33958|Lactobacillaceae 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N GHFFDFOM_01393 220668.lp_2720 0.0 997.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,3F4FD@33958|Lactobacillaceae 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS GHFFDFOM_01394 220668.lp_2721 5.35e-133 377.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli,3F3UN@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N GHFFDFOM_01395 220668.lp_2722 4.22e-243 668.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,3F4RT@33958|Lactobacillaceae 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C GHFFDFOM_01396 220668.lp_2723 0.0 964.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,3F3U7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran GHFFDFOM_01397 220668.lp_2724 0.0 1468.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,3F4IQ@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C GHFFDFOM_01398 220668.lp_2725 6.91e-164 458.0 COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,3F48D@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 GHFFDFOM_01399 220668.lp_2726 1.17e-55 173.0 COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,3F81F@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU06460 PurS GHFFDFOM_01400 220668.lp_2727 3.39e-168 470.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli,3F44Z@33958|Lactobacillaceae 91061|Bacilli F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt GHFFDFOM_01401 220668.lp_2728 8.24e-270 738.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,3F3YV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp GHFFDFOM_01402 220668.lp_2729 3.77e-104 301.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,3F6P0@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC GHFFDFOM_01403 220668.lp_2732 1.01e-308 842.0 COG0431@1|root,COG2461@1|root,COG0431@2|Bacteria,COG2461@2|Bacteria,1TPRA@1239|Firmicutes,4HDA5@91061|Bacilli,3F44U@33958|Lactobacillaceae 91061|Bacilli S reductase XK27_09615 - 1.5.1.36 ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 - R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 - - - FMN_red,PAS_10 GHFFDFOM_01404 220668.lp_2733 9.92e-143 402.0 COG0431@1|root,COG0431@2|Bacteria,1TT2S@1239|Firmicutes,4HBQI@91061|Bacilli,3F544@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red GHFFDFOM_01405 220668.lp_2734 2.01e-243 668.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,3F49I@33958|Lactobacillaceae 91061|Bacilli H Bacterial lipoate protein ligase C-terminus lplL - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C GHFFDFOM_01406 220668.lp_2735 4.81e-188 522.0 COG2365@1|root,COG2365@2|Bacteria,1VBGE@1239|Firmicutes,4HN6J@91061|Bacilli,3FBJY@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family ptp3 - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 GHFFDFOM_01407 220668.lp_2736 5.95e-153 429.0 COG3338@1|root,COG3338@2|Bacteria,1V16J@1239|Firmicutes,4HA62@91061|Bacilli,3F7DZ@33958|Lactobacillaceae 91061|Bacilli P Eukaryotic-type carbonic anhydrase cah - 4.2.1.1 ko:K01674 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Carb_anhydrase GHFFDFOM_01408 220668.lp_2737 6.89e-190 527.0 COG4814@1|root,COG4814@2|Bacteria,1U5EG@1239|Firmicutes,4IF5Z@91061|Bacilli,3F5R2@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 GHFFDFOM_01409 220668.lp_2738 3.7e-233 641.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H9YJ@91061|Bacilli,3F3XA@33958|Lactobacillaceae 91061|Bacilli EJ Asparaginase ansB - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase GHFFDFOM_01410 220668.lp_2739 2.05e-178 497.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,3F3MG@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein cysA - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_01411 220668.lp_2740 0.0 1102.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4HAZG@91061|Bacilli,3F45H@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX GHFFDFOM_01412 220668.lp_2741 4.76e-56 174.0 29P7J@1|root,30A5N@2|Bacteria,1U68A@1239|Firmicutes,4IFZ1@91061|Bacilli,3F7AC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01413 220668.lp_2742 8.2e-81 239.0 COG1725@1|root,COG1725@2|Bacteria,1VAC6@1239|Firmicutes,4HKVW@91061|Bacilli,3F721@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, GntR family - - - - - - - - - - - - GntR GHFFDFOM_01414 220668.lp_2743 7.89e-212 585.0 COG1131@1|root,COG1131@2|Bacteria,1TS5Y@1239|Firmicutes,4HBUA@91061|Bacilli,3F4BF@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_01415 220668.lp_2744 4.65e-188 523.0 28V9H@1|root,2ZHCF@2|Bacteria,1W561@1239|Firmicutes,4I11A@91061|Bacilli,3F5C3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01416 220668.lp_2745 2.7e-104 301.0 COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,4HNHG@91061|Bacilli,3F4Z0@33958|Lactobacillaceae 91061|Bacilli T universal stress protein usp5 - - - - - - - - - - - Usp GHFFDFOM_01417 220668.lp_2746 1.08e-47 152.0 29PWF@1|root,30AUT@2|Bacteria,1U74P@1239|Firmicutes,4IGZB@91061|Bacilli,3F8Z0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01418 220668.lp_2747 2.32e-94 275.0 COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,4HNK7@91061|Bacilli,3F4GH@33958|Lactobacillaceae 91061|Bacilli S Teichoic acid glycosylation protein gtcA - - - - - - - - - - - GtrA GHFFDFOM_01419 220668.lp_3218 5.01e-204 566.0 COG3595@1|root,COG3595@2|Bacteria,1VJU7@1239|Firmicutes,4HQ8U@91061|Bacilli,3F6HR@33958|Lactobacillaceae 91061|Bacilli S Putative adhesin - - - - - - - - - - - - DUF4097 GHFFDFOM_01420 220668.lp_3217 6.03e-133 379.0 COG4709@1|root,COG4709@2|Bacteria,1VD2S@1239|Firmicutes,4HN8T@91061|Bacilli,3FBMR@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1700) - - - - - - - - - - - - DUF1700 GHFFDFOM_01421 220668.lp_3216 8.52e-70 210.0 COG1695@1|root,COG1695@2|Bacteria,1VACN@1239|Firmicutes,4HQIW@91061|Bacilli,3FCDA@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - ko:K10947 - - - - ko00000,ko03000 - - - PadR GHFFDFOM_01422 220668.lp_3215 1.78e-126 360.0 COG4640@1|root,COG4640@2|Bacteria 2|Bacteria KT response to antibiotic - - - - - - - - - - - - zinc_ribbon_2 GHFFDFOM_01423 220668.lp_3214 1.26e-161 456.0 COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HBRP@91061|Bacilli,3F4MH@33958|Lactobacillaceae 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family tcyA - - ko:K02424 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 GHFFDFOM_01424 220668.lp_3211 3.02e-176 491.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4HUHS@91061|Bacilli,3F4YF@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein - - - ko:K10010 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.10,3.A.1.3.14 - - ABC_tran GHFFDFOM_01425 220668.lp_3210 2.11e-158 445.0 COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,4H9N1@91061|Bacilli,3F4QR@33958|Lactobacillaceae 91061|Bacilli E ABC transporter tcyB - - ko:K10009 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 - - BPD_transp_1 GHFFDFOM_01426 220668.lp_3209 2.13e-167 470.0 COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HBRP@91061|Bacilli,3F4MH@33958|Lactobacillaceae 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family tcyA - - ko:K02424 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 GHFFDFOM_01427 220668.lp_3207 2.07e-302 823.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4H9M3@91061|Bacilli,3F4AH@33958|Lactobacillaceae 91061|Bacilli EK Aminotransferase, class I - - - - - - - - - - - - Aminotran_1_2 GHFFDFOM_01428 220668.lp_3206 3.36e-216 596.0 COG0583@1|root,COG0583@2|Bacteria,1TP9T@1239|Firmicutes,4HCXX@91061|Bacilli,3F4HW@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_01429 220668.lp_3205 3.14e-190 529.0 COG4814@1|root,COG4814@2|Bacteria,1U56H@1239|Firmicutes,4IEXS@91061|Bacilli,3F4XW@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 GHFFDFOM_01430 220668.lp_3204 3.35e-288 789.0 COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,4HA8N@91061|Bacilli,3F4GI@33958|Lactobacillaceae 91061|Bacilli F Nucleoside nupG GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015212,GO:0015213,GO:0015214,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015506,GO:0015672,GO:0015858,GO:0015861,GO:0015862,GO:0015864,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072531,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1901505,GO:1901642,GO:1902600 - ko:K16323 - - - - ko00000,ko02000 2.A.41.1 - - Nucleos_tra2_C,Nucleos_tra2_N GHFFDFOM_01431 220668.lp_3201 1.05e-167 469.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,3F3ZX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB GHFFDFOM_01432 220668.lp_3200 7.39e-192 533.0 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,3F4RU@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc GHFFDFOM_01433 60520.HR47_05635 1.01e-175 490.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,3F4AE@33958|Lactobacillaceae 91061|Bacilli D Sporulation initiation inhibitor soj GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 GHFFDFOM_01434 220668.lp_3198 1.76e-201 559.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,3F47R@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc GHFFDFOM_01435 1136177.KCA1_2620 1.4e-40 133.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli,3F823@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF951) yyzM - - - - - - - - - - - DUF951 GHFFDFOM_01436 220668.lp_3196 6.6e-255 700.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,3F3TK@33958|Lactobacillaceae 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C GHFFDFOM_01437 220668.lp_3195 3.49e-160 450.0 COG4858@1|root,COG4858@2|Bacteria,1VF5N@1239|Firmicutes,4HH7B@91061|Bacilli,3F4JS@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1129) - - - - - - - - - - - - DUF1129 GHFFDFOM_01438 220668.lp_3194 3.49e-270 740.0 COG0516@1|root,COG0516@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,3F3XN@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH GHFFDFOM_01439 220668.lp_3193 3.3e-208 577.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,3F9BD@33958|Lactobacillaceae 91061|Bacilli M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3 GHFFDFOM_01440 220668.lp_3192 2.4e-161 452.0 COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,4HM4F@91061|Bacilli,3F5F5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 GHFFDFOM_01441 220668.lp_3191 1.14e-159 447.0 COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,3F3Y0@33958|Lactobacillaceae 91061|Bacilli K response regulator vanR - - - - - - - - - - - Response_reg,Trans_reg_C GHFFDFOM_01442 220668.lp_3190 5.61e-273 747.0 COG5002@1|root,COG5002@2|Bacteria,1TPB6@1239|Firmicutes,4HARU@91061|Bacilli,3F479@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase hpk31 - - - - - - - - - - - HATPase_c,HisKA GHFFDFOM_01443 220668.lp_3189 5.36e-305 833.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,3F43S@33958|Lactobacillaceae 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 GHFFDFOM_01444 220668.lp_3187 1.66e-116 333.0 COG1247@1|root,COG1247@2|Bacteria,1V3V3@1239|Firmicutes,4HHNY@91061|Bacilli,3F70T@33958|Lactobacillaceae 91061|Bacilli M Acetyltransferase (GNAT) domain ywnH GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_3,Acetyltransf_4 GHFFDFOM_01445 220668.lp_3185 2.05e-167 469.0 COG1296@1|root,COG1296@2|Bacteria,1U49T@1239|Firmicutes,4HDIJ@91061|Bacilli,3F45S@33958|Lactobacillaceae 91061|Bacilli E branched-chain amino acid - - - - - - - - - - - - AzlC GHFFDFOM_01446 1136177.KCA1_2610 5.93e-73 219.0 COG4392@1|root,COG4392@2|Bacteria,1UF1S@1239|Firmicutes,4HQ7J@91061|Bacilli,3F7GD@33958|Lactobacillaceae 91061|Bacilli S branched-chain amino acid - - - - - - - - - - - - AzlD GHFFDFOM_01447 60520.HR47_05710 3.37e-141 402.0 COG0730@1|root,COG0730@2|Bacteria,1VBCY@1239|Firmicutes,4HSSU@91061|Bacilli,3F41D@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE GHFFDFOM_01448 220668.lp_3180 1.08e-60 187.0 2B3UH@1|root,31WIC@2|Bacteria,1U6SM@1239|Firmicutes,4IGK6@91061|Bacilli,3F8F1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01449 220668.lp_3179 9.69e-99 286.0 2E529@1|root,32ZVG@2|Bacteria,1VGFJ@1239|Firmicutes,4IFFI@91061|Bacilli,3F6D6@33958|Lactobacillaceae 91061|Bacilli S Psort location Cytoplasmic, score - - - - - - - - - - - - - GHFFDFOM_01450 220668.lp_3178 2.47e-125 357.0 2DPC1@1|root,331GC@2|Bacteria,1VFZ2@1239|Firmicutes,4IRCJ@91061|Bacilli,3FBNK@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4352) - - - - - - - - - - - - DUF4352 GHFFDFOM_01451 220668.lp_3177 9.58e-35 123.0 2E61F@1|root,330QP@2|Bacteria,1VASH@1239|Firmicutes,4HKBT@91061|Bacilli,3F777@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF4064) - - - - - - - - - - - - DUF4064 GHFFDFOM_01452 220668.lp_3176 1.08e-255 701.0 COG0515@1|root,COG0515@2|Bacteria,1V7U3@1239|Firmicutes,4HKIZ@91061|Bacilli,3F5QP@33958|Lactobacillaceae 91061|Bacilli KLT Protein tyrosine kinase pkn2 - - - - - - - - - - - Pkinase GHFFDFOM_01453 220668.lp_3175 4.04e-211 584.0 28JAP@1|root,2Z95J@2|Bacteria,1V602@1239|Firmicutes,4IVBI@91061|Bacilli,3F4EN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01454 220668.lp_3174 3.66e-295 804.0 COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,4HDKI@91061|Bacilli,3F3PA@33958|Lactobacillaceae 91061|Bacilli M cyclopropane-fatty-acyl-phospholipid synthase cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS GHFFDFOM_01455 220668.lp_3173 6.04e-150 432.0 2EIB1@1|root,33C2F@2|Bacteria,1VM03@1239|Firmicutes,4HS05@91061|Bacilli,3F5MI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01456 220668.lp_3172 7.62e-270 739.0 COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,4HDE3@91061|Bacilli,3F540@33958|Lactobacillaceae 91061|Bacilli GK ROK family xylR - - - - - - - - - - - HTH_24,ROK GHFFDFOM_01457 220668.lp_3171 9.26e-233 643.0 COG0628@1|root,COG0628@2|Bacteria,1TSBK@1239|Firmicutes,4HBYJ@91061|Bacilli,3F46E@33958|Lactobacillaceae 91061|Bacilli K AI-2E family transporter ydbI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport GHFFDFOM_01458 220668.lp_3170 5.06e-168 469.0 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,3F3SK@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 GHFFDFOM_01459 60520.HR47_05780 6.33e-143 406.0 COG0500@1|root,COG2226@2|Bacteria,1UHIX@1239|Firmicutes,4HFT8@91061|Bacilli,3F695@33958|Lactobacillaceae 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 GHFFDFOM_01460 60520.HR47_05785 1.49e-48 155.0 29PB4@1|root,30A9A@2|Bacteria,1U6CS@1239|Firmicutes,4IG4H@91061|Bacilli,3F7MC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01461 936140.AEOT01000010_gene595 1.43e-148 421.0 COG0561@1|root,COG0561@2|Bacteria,1TQTU@1239|Firmicutes,4HDUC@91061|Bacilli,3F6IF@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 GHFFDFOM_01462 525318.HMPREF0497_2166 7.56e-09 54.3 29WTM@1|root,30IF0@2|Bacteria,1U77Z@1239|Firmicutes,4IH2S@91061|Bacilli,3F93A@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3781) - - - - - - - - - - - - DUF3781 GHFFDFOM_01463 543734.LCABL_14270 2.03e-101 306.0 COG0642@1|root,COG2205@2|Bacteria,1UZKD@1239|Firmicutes,4ITNE@91061|Bacilli,3FBXA@33958|Lactobacillaceae 91061|Bacilli T GHKL domain - - - - - - - - - - - - HATPase_c,HisKA GHFFDFOM_01464 1423732.BALS01000006_gene629 9.95e-101 298.0 COG0745@1|root,COG0745@2|Bacteria,1UYA6@1239|Firmicutes,4IQ4T@91061|Bacilli,3F6RJ@33958|Lactobacillaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C GHFFDFOM_01465 568703.LGG_01227 2.32e-142 410.0 COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HAGA@91061|Bacilli,3FC3R@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system bcrA - - ko:K01990,ko:K19309 ko02010,map02010 M00254,M00747 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.131.1 - - ABC_tran GHFFDFOM_01466 1437605.BACT_1008 2.9e-67 216.0 2EGU7@1|root,33AKD@2|Bacteria,2IECH@201174|Actinobacteria,4CZZV@85004|Bifidobacteriales 201174|Actinobacteria S ABC transporter, permease protein, probably The 2 or 3 component bacitracin-resistance efflex pump, BcrAB or BcrABC - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_4 GHFFDFOM_01467 220668.lp_3219 0.0 1197.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system pts26BCA - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC GHFFDFOM_01468 220668.lp_3220 0.0 1157.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein malL - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,DUF3459,Malt_amylase_C GHFFDFOM_01469 220668.lp_3221 1.06e-232 641.0 COG1609@1|root,COG1609@2|Bacteria,1TRHK@1239|Firmicutes,4HB9P@91061|Bacilli,3F5FI@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding proteins and sugar binding domain of LacI family purR2 - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 GHFFDFOM_01470 220668.lp_3223 4.35e-262 717.0 COG1434@1|root,COG1434@2|Bacteria,1UR34@1239|Firmicutes,4HDF2@91061|Bacilli,3F4J5@33958|Lactobacillaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 GHFFDFOM_01471 220668.lp_3224 9.95e-165 462.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,3F4P1@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0014) ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 GHFFDFOM_01472 220668.lp_3225 1.76e-152 428.0 COG4619@1|root,COG4619@2|Bacteria,1V3DQ@1239|Firmicutes,4HHGU@91061|Bacilli,3F4UY@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ybbL - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran GHFFDFOM_01473 220668.lp_3226 0.0 947.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F4GQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr GHFFDFOM_01474 220668.lp_3227 6.26e-101 292.0 2AC8T@1|root,311TG@2|Bacteria,1U5AV@1239|Firmicutes,4IF2B@91061|Bacilli,3F5EK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01475 220668.lp_3236 2.69e-194 540.0 COG0702@1|root,COG0702@2|Bacteria,1TT90@1239|Firmicutes,4HC1K@91061|Bacilli,3F4UU@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family qorB - 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - NAD_binding_10,NmrA GHFFDFOM_01476 220668.lp_3237 3.54e-190 528.0 COG0561@1|root,COG0561@2|Bacteria,1TSGF@1239|Firmicutes,4HHWU@91061|Bacilli,3F57T@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 GHFFDFOM_01477 220668.lp_3238 3.75e-103 298.0 COG0789@1|root,COG0789@2|Bacteria,1U5BW@1239|Firmicutes,4IF2X@91061|Bacilli,3F5GN@33958|Lactobacillaceae 91061|Bacilli K MerR family regulatory protein - - - - - - - - - - - - MerR_1 GHFFDFOM_01478 220668.lp_3239 2.63e-200 555.0 COG0702@1|root,COG0702@2|Bacteria,1TT90@1239|Firmicutes,4HC1K@91061|Bacilli,3F4UU@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10,NmrA GHFFDFOM_01479 220668.lp_3240 0.0 1254.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system pts28ABC - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC GHFFDFOM_01480 220668.lp_3241 5.08e-164 458.0 COG2231@1|root,COG2231@2|Bacteria,1V4SG@1239|Firmicutes,4HI5U@91061|Bacilli,3F62T@33958|Lactobacillaceae 91061|Bacilli L Base excision DNA repair protein, HhH-GPD family nth2 - - ko:K07457 - - - - ko00000 - - - HhH-GPD GHFFDFOM_01482 220668.lp_3244 8.66e-130 368.0 COG0431@1|root,COG0431@2|Bacteria,1TPRA@1239|Firmicutes,4HDA5@91061|Bacilli,3F5W1@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red GHFFDFOM_01483 220668.lp_3245 3.43e-303 827.0 COG4908@1|root,COG4908@2|Bacteria,1TS0H@1239|Firmicutes,4HKK4@91061|Bacilli,3F4R0@33958|Lactobacillaceae 91061|Bacilli S module of peptide synthetase - - - - - - - - - - - - Condensation GHFFDFOM_01484 220668.lp_3246 1.78e-139 394.0 29P7B@1|root,30A5E@2|Bacteria,1U67Y@1239|Firmicutes,4IFYN@91061|Bacilli,3F79U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01485 220668.lp_3247 1.55e-114 328.0 COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli,3F67J@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Fur family perR - - ko:K03711,ko:K09825 - - - - ko00000,ko03000 - - - FUR GHFFDFOM_01486 220668.lp_3248 1.28e-77 231.0 2F7TF@1|root,3407K@2|Bacteria,1VXH6@1239|Firmicutes,4HXTR@91061|Bacilli,3F6UJ@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun GHFFDFOM_01487 220668.lp_3250 2.63e-48 154.0 295K7@1|root,2ZSXP@2|Bacteria,1W2PI@1239|Firmicutes,4I1YK@91061|Bacilli,3F7SN@33958|Lactobacillaceae 91061|Bacilli S Phospholipase_D-nuclease N-terminal - - - - - - - - - - - - PLDc_N GHFFDFOM_01488 220668.lp_3251 7.93e-217 597.0 COG1409@1|root,COG1409@2|Bacteria,1VJ4D@1239|Firmicutes,4HNZU@91061|Bacilli,3FC18@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - 3.1.4.17,3.1.4.53 ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 - R00191,R01234 RC00296 ko00000,ko00001,ko01000 - - - Metallophos GHFFDFOM_01489 220668.lp_3252 2.8e-135 382.0 COG1670@1|root,COG1670@2|Bacteria,1VC3X@1239|Firmicutes,4HKVZ@91061|Bacilli,3F5IW@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3,Acetyltransf_4 GHFFDFOM_01490 220668.lp_3254 4.14e-84 249.0 COG1380@1|root,COG1380@2|Bacteria,1VIGA@1239|Firmicutes,4HN5Z@91061|Bacilli,3F6PC@33958|Lactobacillaceae 91061|Bacilli S LrgA family lrgA - - ko:K05338 ko02020,map02020 - - - ko00000,ko00001,ko02000 1.E.14.1 - - LrgA GHFFDFOM_01491 220668.lp_3255 2.88e-164 460.0 COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,4HE2Y@91061|Bacilli,3F4A8@33958|Lactobacillaceae 91061|Bacilli M LrgB-like family lrgB - - ko:K05339 ko02020,map02020 - - - ko00000,ko00001 - - - LrgB GHFFDFOM_01492 220668.lp_3256 3.84e-186 519.0 COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli,3F4CW@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family WQ51_01275 - - - - - - - - - - - DegV GHFFDFOM_01493 220668.lp_3257 1.03e-34 118.0 29PW6@1|root,30AUH@2|Bacteria,1U74D@1239|Firmicutes,4IGZ0@91061|Bacilli,3F8YM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01494 220668.lp_3259 2.45e-151 427.0 COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,4HB8Z@91061|Bacilli,3F4E2@33958|Lactobacillaceae 91061|Bacilli S Putative neutral zinc metallopeptidase yugP - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 GHFFDFOM_01495 220668.lp_3262 0.0 1013.0 COG1233@1|root,COG1233@2|Bacteria,1TV0D@1239|Firmicutes,4IFA0@91061|Bacilli,3F62G@33958|Lactobacillaceae 91061|Bacilli Q Flavin containing amine oxidoreductase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase GHFFDFOM_01496 220668.lp_3263 1.04e-212 587.0 COG1562@1|root,COG1562@2|Bacteria,1TQHF@1239|Firmicutes,4HA1A@91061|Bacilli,3F8JK@33958|Lactobacillaceae 91061|Bacilli I Squalene/phytoene synthase crtM - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY GHFFDFOM_01497 220668.lp_3265 4.68e-235 645.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta - - - ko:K06889 - - - - ko00000 - - - DLH,FSH1,Hydrolase_4 GHFFDFOM_01498 220668.lp_3266 2.12e-253 696.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,4HA91@91061|Bacilli,3F3V2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase GHFFDFOM_01499 220668.lp_3267 0.0 892.0 COG1249@1|root,COG1249@2|Bacteria,1TS0Z@1239|Firmicutes,4HBYB@91061|Bacilli,3F3K2@33958|Lactobacillaceae 91061|Bacilli C Glutathione reductase gshR3 - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim GHFFDFOM_01500 220668.lp_3268 1.62e-69 210.0 29PMI@1|root,30AJQ@2|Bacteria,1U6SH@1239|Firmicutes,4IGK1@91061|Bacilli,3F8ET@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun GHFFDFOM_01501 220668.lp_3663 2.51e-103 299.0 COG0589@1|root,COG0589@2|Bacteria,1W0BR@1239|Firmicutes,4HXYP@91061|Bacilli,3F5SB@33958|Lactobacillaceae 91061|Bacilli T Universal stress protein family - - - - - - - - - - - - Usp GHFFDFOM_01502 220668.lp_3664 7.43e-130 368.0 COG1695@1|root,COG1695@2|Bacteria,1V6TJ@1239|Firmicutes,4HKXY@91061|Bacilli,3F70A@33958|Lactobacillaceae 91061|Bacilli K Virulence activator alpha C-term padR - - - - - - - - - - - PadR,Vir_act_alpha_C GHFFDFOM_01503 220668.lp_3665 2.71e-135 382.0 COG3479@1|root,COG3479@2|Bacteria,1UY0X@1239|Firmicutes,4HAN3@91061|Bacilli,3F4P4@33958|Lactobacillaceae 91061|Bacilli Q Phenolic acid decarboxylase padC - - ko:K13727 - - - - ko00000,ko01000 - - - PA_decarbox GHFFDFOM_01504 220668.lp_3666 1.13e-182 509.0 COG3971@1|root,COG3971@2|Bacteria,1TQVG@1239|Firmicutes,4HBMC@91061|Bacilli,3F515@33958|Lactobacillaceae 91061|Bacilli Q hydratase mhpD - - ko:K02509 ko00350,ko01120,map00350,map01120 - R04132,R06897 RC01615,RC02595 ko00000,ko00001,ko01000 - - - - GHFFDFOM_01505 220668.lp_3668 3.66e-113 324.0 COG0454@1|root,COG0456@2|Bacteria,1VAYE@1239|Firmicutes,4HM99@91061|Bacilli,3F4YE@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 GHFFDFOM_01506 220668.lp_3669 4.02e-203 562.0 COG1307@1|root,COG1307@2|Bacteria,1V289@1239|Firmicutes,4I3AR@91061|Bacilli,3F4D9@33958|Lactobacillaceae 91061|Bacilli S DegV family degV1 - - - - - - - - - - - DegV GHFFDFOM_01507 220668.lp_3672 9.67e-79 236.0 COG1396@1|root,COG1396@2|Bacteria,1UUXA@1239|Firmicutes,4IFHI@91061|Bacilli,3F6H3@33958|Lactobacillaceae 91061|Bacilli K Bacteriophage CI repressor helix-turn-helix domain - - - - - - - - - - - - HTH_3 GHFFDFOM_01508 220668.lp_3673 0.0 881.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F3QA@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepE - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 GHFFDFOM_01510 220668.lp_3675 2.76e-141 398.0 COG0681@1|root,COG0681@2|Bacteria,1V5YR@1239|Firmicutes,4IR1X@91061|Bacilli,3FBKW@33958|Lactobacillaceae 91061|Bacilli U Belongs to the peptidase S26 family sip3 - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 GHFFDFOM_01511 220668.lp_3676 0.0 1039.0 29Q2R@1|root,30B1D@2|Bacteria,1U7DB@1239|Firmicutes,4IH97@91061|Bacilli,3F9EZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01513 220668.lp_3678 9.06e-211 587.0 COG4072@1|root,COG4072@2|Bacteria,1V92G@1239|Firmicutes,4HIJ2@91061|Bacilli,3F97P@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF916) - - - - - - - - - - - - DUF3324,DUF916 GHFFDFOM_01514 220668.lp_3679 1.31e-143 408.0 2BM49@1|root,32FMM@2|Bacteria,1U5KE@1239|Firmicutes,4IFB7@91061|Bacilli,3F64S@33958|Lactobacillaceae 91061|Bacilli S Cell surface protein - - - - - - - - - - - - WxL GHFFDFOM_01515 220668.lp_3681 0.0 1255.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,3F454@33958|Lactobacillaceae 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc GHFFDFOM_01516 220668.lp_3682 0.0 889.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,3F3WA@33958|Lactobacillaceae 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N GHFFDFOM_01517 220668.lp_3683 1.59e-171 485.0 COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4HHHU@91061|Bacilli,3F5WG@33958|Lactobacillaceae 91061|Bacilli S R3H domain protein jag - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H GHFFDFOM_01518 220668.lp_3684 2.26e-306 834.0 COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,4HDKW@91061|Bacilli,3F4D3@33958|Lactobacillaceae 91061|Bacilli Q Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 GHFFDFOM_01519 220668.lp_3686 0.0 1074.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GHFFDFOM_01520 220668.lp_3687 1.55e-158 449.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,3F3SD@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP GHFFDFOM_01521 1136177.KCA1_3018 3.74e-75 224.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,3F6GS@33958|Lactobacillaceae 91061|Bacilli J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P GHFFDFOM_01522 220668.lp_0001 0.0 887.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,3F3YA@33958|Lactobacillaceae 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N GHFFDFOM_01523 220668.lp_0002 8.19e-267 731.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,3F3ZQ@33958|Lactobacillaceae 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 GHFFDFOM_01524 220668.lp_0004 3.82e-51 161.0 COG2501@1|root,COG2501@2|Bacteria,1VEJ2@1239|Firmicutes,4HNMC@91061|Bacilli,3F803@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein YaaA yaaA - - ko:K14761 - - - - ko00000,ko03009 - - - S4_2 GHFFDFOM_01525 220668.lp_0005 7.24e-263 721.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,3F3Q1@33958|Lactobacillaceae 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N GHFFDFOM_01526 220668.lp_0006 0.0 1274.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,3F48M@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim GHFFDFOM_01527 220668.lp_0007 0.0 1534.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,3F3YM@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV GHFFDFOM_01528 1136177.KCA1_0007 5.95e-65 197.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,3F6ZY@33958|Lactobacillaceae 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 GHFFDFOM_01529 220668.lp_0010 1.68e-108 316.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,3F66N@33958|Lactobacillaceae 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB GHFFDFOM_01530 220668.lp_0011 2.69e-47 151.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,3F7CY@33958|Lactobacillaceae 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 GHFFDFOM_01531 1114972.AUAW01000004_gene333 1.45e-104 314.0 COG0604@1|root,COG0604@2|Bacteria,1VZMF@1239|Firmicutes,4HY0D@91061|Bacilli,3F5Z3@33958|Lactobacillaceae 91061|Bacilli C nadph quinone reductase - - - - - - - - - - - - ADH_zinc_N,ADH_zinc_N_2 GHFFDFOM_01533 1045004.OKIT_0659 3.99e-73 226.0 COG0108@1|root,COG0108@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,4AXGT@81850|Leuconostocaceae 91061|Bacilli H belongs to the DHBP synthase family ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08945 DHBP_synthase,GTP_cyclohydro2 GHFFDFOM_01534 220668.lp_3292 6.88e-24 90.9 2BTZR@1|root,32P89@2|Bacteria,1U8G6@1239|Firmicutes,4IIDZ@91061|Bacilli,3FAY5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01535 220668.lp_3288 2.62e-207 573.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,3F4KJ@33958|Lactobacillaceae 91061|Bacilli P cation diffusion facilitator family transporter czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux GHFFDFOM_01536 60520.HR47_05250 3.47e-71 214.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,3F72A@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 GHFFDFOM_01537 220668.lp_3286 2.94e-149 420.0 COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4HAT2@91061|Bacilli,3F578@33958|Lactobacillaceae 91061|Bacilli S protein, hemolysin III hlyIII - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII GHFFDFOM_01538 220668.lp_3285 1.97e-60 186.0 COG2076@1|root,COG2076@2|Bacteria,1U651@1239|Firmicutes,4IFUS@91061|Bacilli,3F72F@33958|Lactobacillaceae 91061|Bacilli U Small Multidrug Resistance protein qacH - - ko:K03297 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res GHFFDFOM_01539 60520.HR47_05270 1.15e-77 232.0 COG2076@1|root,COG2076@2|Bacteria,1VH7F@1239|Firmicutes 1239|Firmicutes P Small Multidrug Resistance protein - - - ko:K03297 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res GHFFDFOM_01540 220668.lp_3283 4.81e-276 754.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,3F49P@33958|Lactobacillaceae 91061|Bacilli E methionine synthase, vitamin-B12 independent metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 GHFFDFOM_01541 220668.lp_3281 1.54e-228 632.0 COG0628@1|root,COG0628@2|Bacteria,1TSBK@1239|Firmicutes,4HBYJ@91061|Bacilli,3F46E@33958|Lactobacillaceae 91061|Bacilli K AI-2E family transporter ydbI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport GHFFDFOM_01542 220668.lp_3280 1.07e-211 586.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family yeaB - - - - - - - - - - - Cation_efflux,ZT_dimer GHFFDFOM_01543 220668.lp_3279 0.0 1322.0 COG3158@1|root,COG3158@2|Bacteria,1TRUQ@1239|Firmicutes,4HA8Z@91061|Bacilli,3F4CU@33958|Lactobacillaceae 91061|Bacilli P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans GHFFDFOM_01545 220668.lp_3278 0.0 894.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F592@33958|Lactobacillaceae 91061|Bacilli E C-terminus of AA_permease yhdG - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 GHFFDFOM_01546 220668.lp_3275 7.97e-108 311.0 29QAF@1|root,30B9K@2|Bacteria,1U7SB@1239|Firmicutes,4IHPP@91061|Bacilli,3FA3T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01548 220668.lp_3273 0.0 958.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F3SF@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N GHFFDFOM_01549 220668.lp_3272 7.18e-188 521.0 COG2365@1|root,COG2365@2|Bacteria,1V851@1239|Firmicutes,4HVA8@91061|Bacilli,3F5K6@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family ptp2 - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 GHFFDFOM_01550 1136177.KCA1_2679 0.0 1136.0 COG4166@1|root,COG4166@2|Bacteria,1TQVS@1239|Firmicutes,4HCCB@91061|Bacilli,3F9MZ@33958|Lactobacillaceae 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle amiA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0071944 - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GHFFDFOM_01551 1136177.KCA1_2678 0.0 897.0 COG0601@1|root,COG0601@2|Bacteria,1UY5U@1239|Firmicutes,4HEZK@91061|Bacilli,3F9HN@33958|Lactobacillaceae 91061|Bacilli U Binding-protein-dependent transport system inner membrane component amiC GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 GHFFDFOM_01552 1136177.KCA1_2677 6.22e-201 560.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,3F3W3@33958|Lactobacillaceae 91061|Bacilli EP ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N GHFFDFOM_01553 1136177.KCA1_2676 4.72e-244 672.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,3F41T@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY GHFFDFOM_01554 1136177.KCA1_2675 5.45e-182 511.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4HCM4@91061|Bacilli,3F98H@33958|Lactobacillaceae 91061|Bacilli E Oligopeptide/dipeptide transporter, C-terminal region amiF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY GHFFDFOM_01555 220668.lp_3271 7.21e-236 648.0 COG0516@1|root,COG0516@2|Bacteria,1TNYF@1239|Firmicutes,4HA55@91061|Bacilli,3F45K@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaC - 1.7.1.7 ko:K00364 ko00230,map00230 - R01134 RC00457 ko00000,ko00001,ko01000 - - iSB619.SA_RS06660 IMPDH GHFFDFOM_01556 220668.lp_3270 0.0 875.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,3F3RQ@33958|Lactobacillaceae 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt GHFFDFOM_01557 220668.lp_3269 7.41e-315 857.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,3F48P@33958|Lactobacillaceae 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09895 ADSL_C,Lyase_1 GHFFDFOM_01558 525309.HMPREF0494_0055 6e-107 317.0 COG4227@1|root,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,4HKTX@91061|Bacilli,3F5I0@33958|Lactobacillaceae 91061|Bacilli L Psort location Cytoplasmic, score - - - - - - - - - - - - - GHFFDFOM_01559 1423806.JCM15457_456 9.66e-239 660.0 COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,4HF9J@91061|Bacilli,3FCF7@33958|Lactobacillaceae 91061|Bacilli H C-5 cytosine-specific DNA methylase dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase GHFFDFOM_01560 353496.LBU_1699 5.3e-130 386.0 2CXRX@1|root,32T2G@2|Bacteria,1U6C6@1239|Firmicutes,4IG3U@91061|Bacilli,3F7K7@33958|Lactobacillaceae 91061|Bacilli L NgoFVII restriction endonuclease - - - - - - - - - - - - RE_NgoFVII GHFFDFOM_01561 1423806.JCM15457_459 2.45e-280 785.0 COG0610@1|root,COG0610@2|Bacteria,1UIN3@1239|Firmicutes,4ITC7@91061|Bacilli,3F50P@33958|Lactobacillaceae 91061|Bacilli V Z1 domain - - - - - - - - - - - - Z1 GHFFDFOM_01562 904306.HMPREF9192_1917 2.81e-70 230.0 2C171@1|root,2Z7ZR@2|Bacteria,1VCWV@1239|Firmicutes 1239|Firmicutes S SIR2-like domain - - - - - - - - - - - - SIR2_2 GHFFDFOM_01563 904306.HMPREF9192_1918 2.12e-173 515.0 COG0433@1|root,COG0433@2|Bacteria,1V8WX@1239|Firmicutes 1239|Firmicutes S Domain of unknown function DUF87 - - - - - - - - - - - - - GHFFDFOM_01564 1423743.JCM14108_3234 1.79e-132 376.0 COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,4HCFF@91061|Bacilli,3F429@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed pinR1 - - - - - - - - - - - HTH_7,Resolvase GHFFDFOM_01565 334390.LAF_0679 2.81e-198 550.0 COG1131@1|root,COG1131@2|Bacteria,1V0AH@1239|Firmicutes,4HD15@91061|Bacilli,3FBFC@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system cylA - - ko:K11050 ko02010,map02010 M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1.130 - - ABC_tran GHFFDFOM_01566 334390.LAF_0680 2.31e-179 501.0 COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,4HFNX@91061|Bacilli,3F6AK@33958|Lactobacillaceae 91061|Bacilli V ABC-2 type transporter cylB - - ko:K11051 ko02010,map02010 M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1.130 - - ABC2_membrane,ABC2_membrane_3 GHFFDFOM_01567 278197.PEPE_0498 2.64e-214 592.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - - GHFFDFOM_01568 1423815.BACR01000048_gene2300 0.0 1101.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,4HAYH@91061|Bacilli,3F3QX@33958|Lactobacillaceae 91061|Bacilli S Myosin-crossreactive antigen mycA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046983,GO:0048037,GO:0050151,GO:0050660,GO:0050662,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA GHFFDFOM_01569 1423806.JCM15457_1875 7.03e-39 133.0 2F7TF@1|root,3407K@2|Bacteria,1VXH6@1239|Firmicutes,4HXTR@91061|Bacilli,3F6UJ@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun GHFFDFOM_01570 585506.HMPREF0877_1448 2.06e-38 133.0 COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4HG5J@91061|Bacilli,4AZ3V@81850|Leuconostocaceae 91061|Bacilli L Integrase - - - - - - - - - - - - Phage_integrase GHFFDFOM_01571 60520.HR47_00100 3.39e-32 117.0 COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4IEJ7@91061|Bacilli,3F4SP@33958|Lactobacillaceae 91061|Bacilli L Integrase - - - - - - - - - - - - Phage_integrase GHFFDFOM_01572 1074451.CRL705_1859 0.0 1037.0 COG0178@1|root,COG0178@2|Bacteria,1TR1H@1239|Firmicutes,4H9RE@91061|Bacilli,3F50Y@33958|Lactobacillaceae 91061|Bacilli L ABC transporter uvrA2 - - - - - - - - - - - ABC_tran GHFFDFOM_01573 1400520.LFAB_12615 1.92e-112 338.0 COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,3F3QK@33958|Lactobacillaceae 91061|Bacilli P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family napA - - - - - - - - - - - Na_H_Exchanger GHFFDFOM_01576 1302286.BAOT01000074_gene2195 9.61e-87 258.0 COG3293@1|root,COG3293@2|Bacteria,1U67N@1239|Firmicutes,4IFY7@91061|Bacilli,3F79E@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_2 GHFFDFOM_01577 1071400.LBUCD034_1016 5.8e-46 150.0 COG3293@1|root,COG3293@2|Bacteria,1U5ZT@1239|Firmicutes,4IFNT@91061|Bacilli,3F6RW@33958|Lactobacillaceae 91061|Bacilli L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 GHFFDFOM_01578 1302286.BAOT01000072_gene2188 1.41e-195 550.0 COG2524@1|root,COG4175@1|root,COG2524@2|Bacteria,COG4175@2|Bacteria,1UHNE@1239|Firmicutes,4HA9P@91061|Bacilli,3FC38@33958|Lactobacillaceae 91061|Bacilli E glycine betaine gbuA - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS GHFFDFOM_01579 1122149.BACN01000023_gene583 9.64e-129 374.0 COG4176@1|root,COG4176@2|Bacteria,1UHRI@1239|Firmicutes,4IS7D@91061|Bacilli,3F4W7@33958|Lactobacillaceae 91061|Bacilli E glycine betaine gbuB - - ko:K02001 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 GHFFDFOM_01580 1423806.JCM15457_1481 1.03e-129 378.0 COG2113@1|root,COG2113@2|Bacteria,1TP82@1239|Firmicutes,4H9MM@91061|Bacilli,3F4B3@33958|Lactobacillaceae 91061|Bacilli E glycine betaine gbuC - - ko:K02001,ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC GHFFDFOM_01581 1423747.BAMJ01000064_gene2174 6.79e-25 103.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HC0Q@91061|Bacilli,3FB40@33958|Lactobacillaceae 91061|Bacilli L Transposase isp - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 GHFFDFOM_01582 913848.AELK01000172_gene1695 1.19e-22 94.7 COG0589@1|root,COG0589@2|Bacteria,1U425@1239|Firmicutes,4I3ZI@91061|Bacilli,3F6XU@33958|Lactobacillaceae 91061|Bacilli T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp GHFFDFOM_01583 334390.LAF_0706 2.34e-127 367.0 COG3316@1|root,COG3316@2|Bacteria,1TTKR@1239|Firmicutes,4HCB4@91061|Bacilli,3F4NE@33958|Lactobacillaceae 91061|Bacilli L DDE domain tnp1216 - - ko:K07498 - - - - ko00000 - - - DDE_Tnp_IS240 GHFFDFOM_01586 220668.lp_0551 0.0 934.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,3F4WU@33958|Lactobacillaceae 91061|Bacilli U amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 GHFFDFOM_01587 220668.lp_0552 6.09e-194 537.0 COG1409@1|root,COG1409@2|Bacteria,1VHY9@1239|Firmicutes,4HPAR@91061|Bacilli,3F3SW@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos GHFFDFOM_01591 220668.lp_0555 9.02e-66 202.0 COG1917@1|root,COG1917@2|Bacteria,1TTZM@1239|Firmicutes,4IFX2@91061|Bacilli,3F77A@33958|Lactobacillaceae 91061|Bacilli S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 GHFFDFOM_01592 220668.lp_0556 9.69e-72 216.0 COG1917@1|root,COG1917@2|Bacteria,1V6IB@1239|Firmicutes,4HNBA@91061|Bacilli,3F6JU@33958|Lactobacillaceae 91061|Bacilli S Cupin domain - - - - - - - - - - - - Cupin_2 GHFFDFOM_01593 220668.lp_0557 3.77e-213 587.0 COG0639@1|root,COG0639@2|Bacteria,1V1HN@1239|Firmicutes,4HF40@91061|Bacilli,3F401@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase pphA - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos GHFFDFOM_01594 220668.lp_0558 9.2e-247 679.0 COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,4HEW7@91061|Bacilli,3F4CJ@33958|Lactobacillaceae 91061|Bacilli P Citrate transporter ysdE - - - - - - - - - - - CitMHS GHFFDFOM_01595 220668.lp_0559 1.06e-195 542.0 COG3201@1|root,COG3201@2|Bacteria,1UYDN@1239|Firmicutes,4HJE5@91061|Bacilli,3F469@33958|Lactobacillaceae 91061|Bacilli H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter GHFFDFOM_01596 220668.lp_0561 6.24e-174 486.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4HCBY@91061|Bacilli,3FB7S@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer GHFFDFOM_01597 220668.lp_0562 2.92e-280 765.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,3F40F@33958|Lactobacillaceae 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 GHFFDFOM_01598 220668.lp_0563 5.41e-160 449.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,3F4D0@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein yvoA_2 - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA GHFFDFOM_01599 220668.lp_0564 8.06e-177 492.0 COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,4HH6B@91061|Bacilli,3F4WB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid tagA - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB GHFFDFOM_01600 220668.lp_0565 0.0 987.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,3F3K7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase GHFFDFOM_01601 220668.lp_0566 5.27e-197 546.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli,3F43Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase GHFFDFOM_01602 220668.lp_0567 0.0 1645.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase GHFFDFOM_01603 220668.lp_0568 6.3e-95 277.0 2E7AN@1|root,331U3@2|Bacteria,1VFU9@1239|Firmicutes,4HP1H@91061|Bacilli,3F69A@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - - GHFFDFOM_01604 220668.lp_0569 0.0 1403.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,3F415@33958|Lactobacillaceae 91061|Bacilli K Tex-like protein N-terminal domain protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF GHFFDFOM_01605 220668.lp_0570 1.53e-106 306.0 COG3091@1|root,COG3091@2|Bacteria,1V6NU@1239|Firmicutes,4HIHY@91061|Bacilli,3F703@33958|Lactobacillaceae 91061|Bacilli S Belongs to the SprT family ydcK - - ko:K03095 - - - - ko00000 - - - SprT-like,Zn_ribbon_SprT GHFFDFOM_01606 220668.lp_0571 1.71e-302 825.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,3F5BM@33958|Lactobacillaceae 91061|Bacilli E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 GHFFDFOM_01607 220668.lp_0572 6.91e-201 557.0 COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli,3F44T@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06620 GHMP_kinases_C,GHMP_kinases_N GHFFDFOM_01611 220668.lp_1064 1.29e-254 704.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 GHFFDFOM_01619 220668.lp_1012 1.62e-294 805.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,3F3M6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b GHFFDFOM_01620 220668.lp_1011 1.11e-148 418.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,3F488@33958|Lactobacillaceae 91061|Bacilli F deoxynucleoside kinase dgk2 - - - - - - - - - - - dNK GHFFDFOM_01621 220668.lp_1010 1.06e-152 432.0 COG1876@1|root,COG1876@2|Bacteria,1V6U8@1239|Firmicutes,4HJCV@91061|Bacilli,3F5PF@33958|Lactobacillaceae 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase dacB - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY GHFFDFOM_01622 220668.lp_1008 0.0 918.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,3F4BG@33958|Lactobacillaceae 91061|Bacilli E amino acid lysP - - ko:K03293,ko:K11733 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.2 - - AA_permease GHFFDFOM_01623 220668.lp_1005 0.0 1093.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli,3FCE6@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family alsS - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GHFFDFOM_01624 220668.lp_1004 1.7e-118 339.0 COG1959@1|root,COG1959@2|Bacteria,1VAMC@1239|Firmicutes,4HN90@91061|Bacilli,3F4Y9@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - Rrf2 GHFFDFOM_01625 220668.lp_1003 3.03e-129 367.0 COG1670@1|root,COG1670@2|Bacteria,1V49W@1239|Firmicutes,4HHAP@91061|Bacilli,3F5A6@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain yjcK - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 GHFFDFOM_01626 220668.lp_1002 2.24e-197 546.0 COG0657@1|root,COG0657@2|Bacteria,1V7DQ@1239|Firmicutes,4HK24@91061|Bacilli,3FBDR@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 GHFFDFOM_01627 220668.lp_1001 2.05e-153 431.0 COG0671@1|root,COG0671@2|Bacteria,1VY85@1239|Firmicutes,4HXM4@91061|Bacilli,3F4DD@33958|Lactobacillaceae 91061|Bacilli I phosphatase - - - - - - - - - - - - PAP2 GHFFDFOM_01628 220668.lp_1000 6.72e-242 665.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr GHFFDFOM_01629 220668.lp_0999 7.76e-100 290.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,3F63I@33958|Lactobacillaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 GHFFDFOM_01630 220668.lp_0998 1.87e-168 471.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,3F4XE@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE GHFFDFOM_01631 220668.lp_0997 1.78e-42 138.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3F7FW@33958|Lactobacillaceae 91061|Bacilli K Cold shock protein cspC - - ko:K03704 - - - - ko00000,ko03000 - - - CSD GHFFDFOM_01632 220668.lp_0996 2.94e-155 435.0 COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,4HH06@91061|Bacilli,3F405@33958|Lactobacillaceae 91061|Bacilli K iron dependent repressor mntR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA GHFFDFOM_01633 220668.lp_0995 1.36e-77 231.0 29PSZ@1|root,30AR5@2|Bacteria,1U708@1239|Firmicutes,4IGUJ@91061|Bacilli,3F8T2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01634 220668.lp_0992 7.79e-112 320.0 COG0789@1|root,COG0789@2|Bacteria,1VZ9X@1239|Firmicutes,4HYI3@91061|Bacilli,3FBR0@33958|Lactobacillaceae 91061|Bacilli K MerR HTH family regulatory protein - - - - - - - - - - - - MerR_1 GHFFDFOM_01635 220668.lp_0991 0.0 938.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 GHFFDFOM_01636 220668.lp_0990 2.72e-152 430.0 2C9UQ@1|root,32RPZ@2|Bacteria,1VDDQ@1239|Firmicutes,4HNJB@91061|Bacilli,3F5X9@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4811) - - - - - - - - - - - - DUF4811 GHFFDFOM_01637 220668.lp_0988 6.7e-166 476.0 2DKJ2@1|root,309ND@2|Bacteria,1U5DG@1239|Firmicutes,4IF4T@91061|Bacilli,3F5MM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01638 220668.lp_3310 1.07e-124 354.0 COG4767@1|root,COG4767@2|Bacteria,1VKIA@1239|Firmicutes,4HNUJ@91061|Bacilli,3F86G@33958|Lactobacillaceae 91061|Bacilli V VanZ like family - - - - - - - - - - - - VanZ GHFFDFOM_01639 220668.lp_3312 1.87e-249 683.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,3F4K3@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase GHFFDFOM_01640 220668.lp_3313 0.0 1524.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,4H9RD@91061|Bacilli,3F53K@33958|Lactobacillaceae 91061|Bacilli C Pyruvate formate lyase-like pflB GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like GHFFDFOM_01641 220668.lp_3314 1.12e-206 570.0 COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,4HACV@91061|Bacilli,3F472@33958|Lactobacillaceae 91061|Bacilli C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine pflA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM GHFFDFOM_01642 220668.lp_3316 8.93e-71 213.0 COG2151@1|root,COG2151@2|Bacteria,1TVP9@1239|Firmicutes,4I3SB@91061|Bacilli,3F793@33958|Lactobacillaceae 91061|Bacilli S Pfam:DUF59 - - - - - - - - - - - - FeS_assembly_P GHFFDFOM_01643 220668.lp_3318 7.39e-224 616.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,3F4U1@33958|Lactobacillaceae 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red GHFFDFOM_01644 220668.lp_3319 5.71e-126 358.0 COG0537@1|root,COG0537@2|Bacteria,1V7FG@1239|Firmicutes,4HIUY@91061|Bacilli,3F6Q4@33958|Lactobacillaceae 91061|Bacilli FG HIT domain - - - - - - - - - - - - HIT GHFFDFOM_01645 220668.lp_3321 5.09e-51 161.0 COG4430@1|root,COG4430@2|Bacteria,1U6UF@1239|Firmicutes,4IGN9@91061|Bacilli,3F8I5@33958|Lactobacillaceae 91061|Bacilli S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA GHFFDFOM_01646 220668.lp_3322 4.29e-101 292.0 2F6G8@1|root,33YZB@2|Bacteria,1VXE5@1239|Firmicutes,4HWYE@91061|Bacilli,3F67Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01647 220668.lp_3323 5.94e-154 432.0 COG2755@1|root,COG2755@2|Bacteria,1VIW7@1239|Firmicutes,4IPPM@91061|Bacilli,3F7KA@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 GHFFDFOM_01648 220668.lp_3324 0.0 1060.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,3F53Q@33958|Lactobacillaceae 91061|Bacilli U Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT GHFFDFOM_01649 220668.lp_3327 0.0 1130.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4JI@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - - - - - - - - - - - E1-E2_ATPase,Hydrolase GHFFDFOM_01651 220668.lp_3330 1.78e-159 447.0 COG2315@1|root,COG2315@2|Bacteria,1VCQP@1239|Firmicutes,4IPPK@91061|Bacilli,3FBDE@33958|Lactobacillaceae 91061|Bacilli S YjbR - - - - - - - - - - - - YjbR GHFFDFOM_01652 220668.lp_3333 1.58e-283 775.0 2EM25@1|root,33ERN@2|Bacteria,1VK4A@1239|Firmicutes,4HRGD@91061|Bacilli,3F53P@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2325) - - - - - - - - - - - - DUF2325 GHFFDFOM_01653 220668.lp_3334 0.0 1103.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HBB2@91061|Bacilli,3F4BJ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - iYO844.BSU14520 Adenine_deam_C,Amidohydro_1 GHFFDFOM_01654 220668.lp_3335 7.12e-256 702.0 COG2222@1|root,COG2222@2|Bacteria,1UI5E@1239|Firmicutes,4ISEC@91061|Bacilli,3F5JC@33958|Lactobacillaceae 91061|Bacilli M SIS domain glmS2 - - - - - - - - - - - SIS GHFFDFOM_01655 220668.lp_0911 2.68e-67 219.0 COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,3F4M8@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - ko:K07487 - - - - ko00000 - - - DDE_Tnp_1,DUF772 GHFFDFOM_01656 913848.AELK01000078_gene1666 1.92e-77 232.0 COG4694@1|root,COG4694@2|Bacteria 2|Bacteria - - prrC - - - - - - - - - - - AAA_13 GHFFDFOM_01657 1423815.BACR01000048_gene2320 8.24e-58 184.0 COG3253@1|root,COG3253@2|Bacteria,1TQB2@1239|Firmicutes,4H9YI@91061|Bacilli,3F4U5@33958|Lactobacillaceae 91061|Bacilli S Chlorite dismutase ywfI - - ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R11522 RC00884 ko00000,ko00001,ko01000 - - - Chlor_dismutase GHFFDFOM_01658 1423815.BACR01000048_gene2319 1.27e-315 861.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HD3T@91061|Bacilli,3F3XF@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein - - - - - - - - - - - - MFS_1,Sugar_tr GHFFDFOM_01659 1423815.BACR01000048_gene2318 5.02e-227 624.0 COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli,3F6EW@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase GHFFDFOM_01660 913848.AELK01000214_gene2326 0.0 950.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F9DJ@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD GHFFDFOM_01661 1423815.BACR01000048_gene2314 3.25e-117 335.0 COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli,3F45M@33958|Lactobacillaceae 91061|Bacilli S PAS domain XK27_04775 - - ko:K09155 - - - - ko00000 - - - DUF438,Hemerythrin,PAS_10 GHFFDFOM_01662 1423734.JCM14202_2816 1.34e-197 548.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli,3F46G@33958|Lactobacillaceae 91061|Bacilli L Integrase core domain is18 - - - - - - - - - - - HTH_21,rve GHFFDFOM_01663 1074451.CRL705_1644 1.01e-51 163.0 COG2963@1|root,COG2963@2|Bacteria,1VIEV@1239|Firmicutes,4HJSC@91061|Bacilli,3F6X7@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 GHFFDFOM_01664 1423734.JCM14202_1411 0.0 918.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli,3F4KT@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 GHFFDFOM_01665 1400520.LFAB_00095 4.31e-203 570.0 COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli,3F4IA@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase GHFFDFOM_01666 1136177.KCA1_0019 7.13e-142 416.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli,3F58E@33958|Lactobacillaceae 91061|Bacilli G Nucleotidyl transferase glgD - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase GHFFDFOM_01667 1423775.BAMN01000002_gene2015 2e-225 635.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,3F3PP@33958|Lactobacillaceae 91061|Bacilli F Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 GHFFDFOM_01668 1400520.LFAB_00110 0.0 1082.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,3F4Z1@33958|Lactobacillaceae 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase GHFFDFOM_01669 1136177.KCA1_0022 2.96e-245 696.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,3F41N@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family malZ - 3.2.1.20,3.2.1.41 ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 - R00028,R00801,R00802,R02111,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - CBM48,GH13,GH31 - Alpha-amylase,Alpha-amylase_N GHFFDFOM_01670 1423734.JCM14202_4064 2.3e-106 313.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli,3F4DZ@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair - - - - - - - - - - - - HTH_38,rve GHFFDFOM_01671 913848.AELK01000082_gene1678 0.0 1135.0 COG0277@1|root,COG0277@2|Bacteria,1UZAG@1239|Firmicutes,4H9ZB@91061|Bacilli,3F59H@33958|Lactobacillaceae 91061|Bacilli C D-lactate dehydrogenase, membrane binding dld - 1.1.5.12 ko:K03777 ko00620,ko01120,map00620,map01120 - R00704,R11591 RC00044 ko00000,ko00001,ko01000 - - - FAD_binding_4,Lact-deh-memb GHFFDFOM_01672 220668.lp_0537 2.79e-226 624.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F3RM@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N GHFFDFOM_01673 220668.lp_0538 8.29e-129 366.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,3F3VZ@33958|Lactobacillaceae 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro GHFFDFOM_01674 220668.lp_0539 0.0 2264.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,3F4KU@33958|Lactobacillaceae 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF GHFFDFOM_01675 220668.lp_0540 0.0 998.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HACG@91061|Bacilli,3F4BV@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein yabM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C GHFFDFOM_01676 220668.lp_0541 7.72e-57 177.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli,3F7JX@33958|Lactobacillaceae 91061|Bacilli J S4 domain protein yabO - - - - - - - - - - - S4 GHFFDFOM_01678 220668.lp_0542 2.02e-83 247.0 COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli,3F76Z@33958|Lactobacillaceae 91061|Bacilli D Septum formation initiator divIC - - ko:K13052 - - - - ko00000,ko03036 - - - DivIC GHFFDFOM_01679 220668.lp_0543 1.07e-103 302.0 COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4HIKM@91061|Bacilli,3F6HV@33958|Lactobacillaceae 91061|Bacilli J RNA binding yabR - - ko:K07571 - - - - ko00000 - - - S1 GHFFDFOM_01680 220668.lp_0545 0.0 880.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,3F4GY@33958|Lactobacillaceae 91061|Bacilli J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C GHFFDFOM_01681 220668.lp_0546 4.3e-124 353.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,3F56C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran GHFFDFOM_01682 220668.lp_0547 0.0 1322.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,3F49Z@33958|Lactobacillaceae 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 GHFFDFOM_01683 220668.lp_0548 7.85e-209 577.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,3F42B@33958|Lactobacillaceae 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 GHFFDFOM_01684 220668.lp_0549 5.33e-243 667.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,3F4C6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus GHFFDFOM_01685 220668.lp_0550 0.0 1008.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,3F439@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon GHFFDFOM_01688 220668.lp_0574 2.5e-208 577.0 COG4990@1|root,COG4990@2|Bacteria,1V7GB@1239|Firmicutes,4I28M@91061|Bacilli,3F5VT@33958|Lactobacillaceae 91061|Bacilli G Peptidase_C39 like family - - - - - - - - - - - - CW_binding_1,Peptidase_C39_2,SH3_8,SLAP GHFFDFOM_01689 1136177.KCA1_0493 6.46e-218 603.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli,3F4PU@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component manL - 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 - - EIIA-man,PTSIIB_sorb GHFFDFOM_01690 1136177.KCA1_0494 4.51e-172 482.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli,3F3V5@33958|Lactobacillaceae 91061|Bacilli G PTS system manM - - ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277 R02630,R08366 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.4 - - EII-Sor GHFFDFOM_01691 1136177.KCA1_0495 1.87e-219 605.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component manN - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA GHFFDFOM_01692 1136177.KCA1_0496 9.05e-85 250.0 COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes,4HIMF@91061|Bacilli,3F719@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF956) manO - - - - - - - - - - - DUF956 GHFFDFOM_01693 220668.lp_0585 0.0 1835.0 COG1221@1|root,COG3933@1|root,COG1221@2|Bacteria,COG3933@2|Bacteria,1VSHE@1239|Firmicutes,4HB6T@91061|Bacilli,3F3N6@33958|Lactobacillaceae 91061|Bacilli K Sigma-54 interaction domain levR - - - - - - - - - - - EIIA-man,PRD,Sigma54_activat GHFFDFOM_01694 220668.lp_0586 7.19e-94 274.0 COG2893@1|root,COG2893@2|Bacteria,1VB2D@1239|Firmicutes,4HMGK@91061|Bacilli,3F68F@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component levD - 2.7.1.191,2.7.1.202 ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276,M00304 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1,4.A.6.1.2 - - EIIA-man GHFFDFOM_01695 220668.lp_0587 4.5e-113 325.0 COG3444@1|root,COG3444@2|Bacteria,1V3X7@1239|Firmicutes,4HH17@91061|Bacilli,3FC7Q@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component manX - 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 - - PTSIIB_sorb GHFFDFOM_01696 220668.lp_0588 3.15e-229 631.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,3F3XP@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C GHFFDFOM_01697 220668.lp_0589 9.24e-85 250.0 COG0511@1|root,COG0511@2|Bacteria,1W5SI@1239|Firmicutes,4I105@91061|Bacilli,3F6T1@33958|Lactobacillaceae 91061|Bacilli I Biotin-requiring enzyme accB1 - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl GHFFDFOM_01698 220668.lp_0590 1.7e-315 859.0 COG0439@1|root,COG0439@2|Bacteria,1VTG5@1239|Firmicutes,4HTGT@91061|Bacilli,3F5P4@33958|Lactobacillaceae 91061|Bacilli I Biotin carboxylase C-terminal domain accC1 - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 GHFFDFOM_01699 220668.lp_0591 1.23e-182 509.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HUXJ@91061|Bacilli,3F6E6@33958|Lactobacillaceae 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD1 - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans GHFFDFOM_01700 220668.lp_0592 9.67e-175 488.0 COG0825@1|root,COG0825@2|Bacteria,1VUKP@1239|Firmicutes,4HVWX@91061|Bacilli,3F6JV@33958|Lactobacillaceae 91061|Bacilli I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit accA1 - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA GHFFDFOM_01701 220668.lp_0593 1.32e-233 649.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr GHFFDFOM_01702 220668.lp_0594 7.53e-215 595.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HB48@91061|Bacilli,3FCFH@33958|Lactobacillaceae 91061|Bacilli S Transporter, auxin efflux carrier (AEC) family protein mleP2 - - ko:K07088 - - - - ko00000 - - - Mem_trans GHFFDFOM_01703 220668.lp_0595 1.73e-226 626.0 COG0697@1|root,COG0697@2|Bacteria,1UHT1@1239|Firmicutes,4HCWY@91061|Bacilli,3F4PS@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA GHFFDFOM_01704 220668.lp_0597 3.3e-166 464.0 COG0588@1|root,COG0588@2|Bacteria,1V2UT@1239|Firmicutes,4HGRK@91061|Bacilli,3F443@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA1 - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 GHFFDFOM_01705 220668.lp_0600 1.12e-147 416.0 COG5549@1|root,COG5549@2|Bacteria,1U5B3@1239|Firmicutes,4IF2F@91061|Bacilli,3F5EV@33958|Lactobacillaceae 91061|Bacilli O Zinc-dependent metalloprotease zmp2 - - - - - - - - - - - Peptidase_M10 GHFFDFOM_01706 220668.lp_0601 0.0 895.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F49B@33958|Lactobacillaceae 91061|Bacilli E Peptidase C1-like family pepC - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 GHFFDFOM_01707 220668.lp_0602 1.62e-158 444.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,3F43N@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A GHFFDFOM_01708 220668.lp_0603 5.96e-69 207.0 COG2388@1|root,COG2388@2|Bacteria,1VEEX@1239|Firmicutes,4HNR2@91061|Bacilli,3F80F@33958|Lactobacillaceae 91061|Bacilli S GCN5-related N-acetyl-transferase yjdJ - - ko:K06975 - - - - ko00000 - - - Acetyltransf_CG GHFFDFOM_01709 220668.lp_0604 9.43e-127 360.0 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli,3F65D@33958|Lactobacillaceae 91061|Bacilli F dUTP diphosphatase dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase GHFFDFOM_01710 220668.lp_0606 0.0 895.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,3F3W8@33958|Lactobacillaceae 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI GHFFDFOM_01711 220668.lp_0607 4.91e-265 728.0 COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,3F46T@33958|Lactobacillaceae 91061|Bacilli S domain protein yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - TRAM GHFFDFOM_01712 220668.lp_0609 0.0 995.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,3F3PR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c GHFFDFOM_01713 220668.lp_0610 0.0 932.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli,3F4K7@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g GHFFDFOM_01714 220668.lp_0611 1.35e-92 270.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli,3F6HS@33958|Lactobacillaceae 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 GHFFDFOM_01715 220668.lp_0612 1.49e-177 495.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,3F3TD@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind GHFFDFOM_01716 220668.lp_0613 1.75e-126 360.0 COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli,3F5KC@33958|Lactobacillaceae 91061|Bacilli S YacP-like NYN domain yacP - - ko:K06962 - - - - ko00000 - - - NYN_YacP GHFFDFOM_01717 220668.lp_0614 4.58e-130 370.0 COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,4HAHR@91061|Bacilli,3FBRS@33958|Lactobacillaceae 91061|Bacilli K Sigma-70 region 2 sigH - - ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko03000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 GHFFDFOM_01718 1136177.KCA1_0523 4.55e-31 108.0 COG0267@1|root,COG0267@2|Bacteria,1VFTQ@1239|Firmicutes,4HR5Q@91061|Bacilli,3F83F@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 GHFFDFOM_01719 220668.lp_0616 1e-39 131.0 COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,4HR1W@91061|Bacilli,3F86Y@33958|Lactobacillaceae 91061|Bacilli U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE GHFFDFOM_01720 220668.lp_0617 1.89e-128 365.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,3F55W@33958|Lactobacillaceae 91061|Bacilli K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG GHFFDFOM_01721 60520.HR47_02280 2.81e-202 561.0 COG4814@1|root,COG4814@2|Bacteria,1V910@1239|Firmicutes,4HF90@91061|Bacilli,3F4RX@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 GHFFDFOM_01722 220668.lp_0619 9.76e-93 271.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,3F64I@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N GHFFDFOM_01723 220668.lp_0620 2.69e-158 444.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,3F3VQ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 GHFFDFOM_01724 220668.lp_0621 3.72e-105 305.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,3F4S4@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 GHFFDFOM_01725 1136177.KCA1_0530 2.76e-74 223.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,3F6YA@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N GHFFDFOM_01727 220668.lp_0624 4.82e-297 809.0 COG0582@1|root,COG0582@2|Bacteria,1VJ2V@1239|Firmicutes,4HPCG@91061|Bacilli,3F4UK@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase GHFFDFOM_01729 220668.lp_0625 1.12e-252 696.0 2DZEC@1|root,32V8J@2|Bacteria,1VD0S@1239|Firmicutes,4HN7Y@91061|Bacilli,3F4K6@33958|Lactobacillaceae 91061|Bacilli S DNA/RNA non-specific endonuclease - - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 GHFFDFOM_01733 220668.lp_0628 2.42e-209 583.0 COG3064@1|root,COG3064@2|Bacteria,1VASR@1239|Firmicutes,4HH3I@91061|Bacilli,3F7F6@33958|Lactobacillaceae 91061|Bacilli M Host cell surface-exposed lipoprotein - - - - - - - - - - - - Lipoprotein_Ltp GHFFDFOM_01734 220668.lp_0629 9.61e-75 224.0 2E9BR@1|root,333JH@2|Bacteria,1VI51@1239|Firmicutes,4HQRQ@91061|Bacilli,3F6MA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF4064 GHFFDFOM_01735 220668.lp_0630 8.76e-99 286.0 COG2856@1|root,COG2856@2|Bacteria,1VGZ4@1239|Firmicutes,4IRTZ@91061|Bacilli,3F7Q0@33958|Lactobacillaceae 91061|Bacilli E IrrE N-terminal-like domain - - - - - - - - - - - - Peptidase_M78 GHFFDFOM_01736 220668.lp_0631 1.32e-80 239.0 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HRBT@91061|Bacilli,3F7WT@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_19,HTH_3 GHFFDFOM_01737 220668.lp_0632 2.43e-36 123.0 COG1476@1|root,COG1476@2|Bacteria,1UUXB@1239|Firmicutes,4IH26@91061|Bacilli,3F92G@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix - - - - - - - - - - - - HTH_3 GHFFDFOM_01739 220668.lp_0634 8.29e-51 160.0 COG1476@1|root,COG1476@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_19,HTH_26,HTH_3,HTH_31 GHFFDFOM_01740 220668.lp_0635 1.13e-36 124.0 2AGH0@1|root,316PJ@2|Bacteria,1U79E@1239|Firmicutes,4IH49@91061|Bacilli,3F95G@33958|Lactobacillaceae 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 GHFFDFOM_01743 220668.lp_0637 3.66e-127 362.0 2C8QA@1|root,30ADW@2|Bacteria,1U6II@1239|Firmicutes,4IGAW@91061|Bacilli,3F7ZD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01746 220668.lp_0640 6.6e-96 278.0 29Q5Y@1|root,30B4U@2|Bacteria,1U7J5@1239|Firmicutes,4IHFZ@91061|Bacilli,3F9SU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01747 220668.lp_0641 1.25e-205 569.0 COG3723@1|root,COG3723@2|Bacteria,1V0QW@1239|Firmicutes,4HBS2@91061|Bacilli,3F47A@33958|Lactobacillaceae 91061|Bacilli L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT GHFFDFOM_01748 220668.lp_0642 4.49e-185 515.0 COG1074@1|root,COG1074@2|Bacteria,1V1UQ@1239|Firmicutes,4HGSG@91061|Bacilli,3F51S@33958|Lactobacillaceae 91061|Bacilli L PDDEXK-like domain of unknown function (DUF3799) pi112 - - - - - - - - - - - DUF3799 GHFFDFOM_01749 220668.lp_0643 1.18e-222 613.0 COG3935@1|root,COG3935@2|Bacteria,1V6IW@1239|Firmicutes,4HJ9G@91061|Bacilli,3FAFI@33958|Lactobacillaceae 91061|Bacilli L Domain of unknown function (DUF4373) - - - - - - - - - - - - DUF4373,DnaB_2,Rep_Org_C GHFFDFOM_01750 220668.lp_2436 4.44e-65 197.0 29Q8U@1|root,30B7X@2|Bacteria,1U7PZ@1239|Firmicutes,4IHMA@91061|Bacilli,3FA00@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01751 220668.lp_0645 6.14e-122 348.0 2F42A@1|root,33WTY@2|Bacteria,1VVJU@1239|Firmicutes,4IHRN@91061|Bacilli,3FA6K@33958|Lactobacillaceae 1239|Firmicutes - - - - - - - - - - - - - - - GHFFDFOM_01752 60520.HR47_13585 3.73e-111 320.0 29Q1G@1|root,30B01@2|Bacteria,1U7BT@1239|Firmicutes,4IH73@91061|Bacilli,3F9AZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01753 220668.lp_0647 8.96e-91 266.0 COG4570@1|root,COG4570@2|Bacteria,1VF2H@1239|Firmicutes,4HJ0V@91061|Bacilli,3F7S9@33958|Lactobacillaceae 91061|Bacilli L Endodeoxyribonuclease RusA rusA - - - - - - - - - - - RusA GHFFDFOM_01759 220668.lp_0653 3.06e-79 235.0 2EGZP@1|root,33ART@2|Bacteria,1VKPB@1239|Firmicutes,4HR69@91061|Bacilli,3F8RA@33958|Lactobacillaceae 91061|Bacilli S YopX protein - - - - - - - - - - - - YopX GHFFDFOM_01760 1400520.LFAB_09155 2.44e-17 80.5 29C1X@1|root,2ZZ0E@2|Bacteria,1W3JH@1239|Firmicutes,4I1E9@91061|Bacilli,3F8BR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF1642 GHFFDFOM_01761 220668.lp_0655 7.97e-30 105.0 29PXZ@1|root,30AWD@2|Bacteria,1U76U@1239|Firmicutes,4IH1M@91061|Bacilli,3F91U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01762 220668.lp_0656 5.27e-107 308.0 2DPRG@1|root,3333C@2|Bacteria,1W30Q@1239|Firmicutes,4I13H@91061|Bacilli,3F7WR@33958|Lactobacillaceae 91061|Bacilli S Phage transcriptional regulator, ArpU family - - - - - - - - - - - - DUF1492 GHFFDFOM_01765 220668.lp_2425 7.73e-23 88.6 2911N@1|root,2ZNP8@2|Bacteria,1W4M5@1239|Firmicutes,4I18X@91061|Bacilli,3F95E@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01767 220668.lp_0660 9.87e-132 374.0 COG3728@1|root,COG3728@2|Bacteria,1U7Y0@1239|Firmicutes,4IHVD@91061|Bacilli,3FAB5@33958|Lactobacillaceae 91061|Bacilli L Terminase small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 GHFFDFOM_01768 220668.lp_0661 0.0 902.0 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HDMY@91061|Bacilli,3FB8E@33958|Lactobacillaceae 91061|Bacilli S Phage terminase, large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C GHFFDFOM_01769 220668.lp_0662 0.0 1068.0 2DB9U@1|root,2Z7Z6@2|Bacteria,1TR67@1239|Firmicutes,4HAC8@91061|Bacilli,3F4VA@33958|Lactobacillaceae 91061|Bacilli S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 GHFFDFOM_01770 220668.lp_0663 8.66e-227 624.0 2DHI2@1|root,2ZZVZ@2|Bacteria,1U5TK@1239|Firmicutes,4IFHJ@91061|Bacilli,3F6H7@33958|Lactobacillaceae 91061|Bacilli S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F GHFFDFOM_01771 220668.lp_0664 1.14e-111 325.0 2C4QM@1|root,32REC@2|Bacteria,1V795@1239|Firmicutes,4I176@91061|Bacilli,3F79P@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4355) - - - - - - - - - - - - DUF4355 GHFFDFOM_01772 220668.lp_0665 1.1e-257 706.0 2BZ9Z@1|root,2Z97E@2|Bacteria,1U6NR@1239|Firmicutes,4HF9M@91061|Bacilli,3F6D9@33958|Lactobacillaceae 91061|Bacilli - - gpG - - - - - - - - - - - - GHFFDFOM_01773 220668.lp_0666 1.8e-83 246.0 2DKRS@1|root,30AII@2|Bacteria,1U6QR@1239|Firmicutes,4IGI1@91061|Bacilli,3F8BJ@33958|Lactobacillaceae 91061|Bacilli S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 GHFFDFOM_01774 220668.lp_0667 7.48e-74 221.0 29PX8@1|root,30AVK@2|Bacteria,1U75Q@1239|Firmicutes,4IH0C@91061|Bacilli,3F90G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01775 220668.lp_0668 2.57e-127 362.0 2CBU8@1|root,30A3G@2|Bacteria,1U653@1239|Firmicutes,4IFUU@91061|Bacilli,3F72I@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01776 220668.lp_0669 1.9e-86 254.0 2CBU9@1|root,30AJS@2|Bacteria,1U6SK@1239|Firmicutes,4IGK4@91061|Bacilli,3F8EY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01777 220668.lp_0670 1.79e-137 389.0 29NUZ@1|root,30A38@2|Bacteria,1U64P@1239|Firmicutes,4IFU8@91061|Bacilli,3F71G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01778 220668.lp_0671 1.41e-115 331.0 29PQZ@1|root,30A8X@2|Bacteria,1U6CB@1239|Firmicutes,4IG3Z@91061|Bacilli,3F7KC@33958|Lactobacillaceae 91061|Bacilli S Phage tail assembly chaperone protein, TAC - - - - - - - - - - - - Phage_TAC_12 GHFFDFOM_01780 220668.lp_0673 0.0 2155.0 COG1196@1|root,COG3953@1|root,COG5412@1|root,COG1196@2|Bacteria,COG3953@2|Bacteria,COG5412@2|Bacteria,1UYS4@1239|Firmicutes,4HEDZ@91061|Bacilli,3FBSQ@33958|Lactobacillaceae 91061|Bacilli D domain protein - - - - - - - - - - - - NLPC_P60,SLT GHFFDFOM_01781 220668.lp_0674 1.19e-182 507.0 COG4722@1|root,COG4722@2|Bacteria,1VHE0@1239|Firmicutes,4HNTT@91061|Bacilli,3F6A1@33958|Lactobacillaceae 91061|Bacilli S phage tail - - - - - - - - - - - - Sipho_tail GHFFDFOM_01782 220668.lp_0675 0.0 1178.0 COG3757@1|root,COG4926@1|root,COG3757@2|Bacteria,COG4926@2|Bacteria,1V80R@1239|Firmicutes,4HJEY@91061|Bacilli 91061|Bacilli M Prophage endopeptidase tail - - - - - - - - - - - - Glyco_hydro_25,Peptidase_M23,Prophage_tail GHFFDFOM_01783 220668.lp_0676 3.46e-241 662.0 COG2755@1|root,COG2755@2|Bacteria,1V8YZ@1239|Firmicutes,4HJGA@91061|Bacilli 91061|Bacilli E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2,Prophage_tail GHFFDFOM_01784 220668.lp_0677 1.92e-141 399.0 29WTK@1|root,30IEZ@2|Bacteria,1UV2A@1239|Firmicutes,4I41W@91061|Bacilli,3F6DE@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF2479) - - - - - - - - - - - - DUF2479,Pectate_lyase_3 GHFFDFOM_01787 220668.lp_0680 2.56e-34 117.0 29QIS@1|root,30BI9@2|Bacteria,1U85W@1239|Firmicutes,4II3E@91061|Bacilli,3FAK5@33958|Lactobacillaceae 91061|Bacilli S Phage uncharacterised protein (Phage_XkdX) - - - - - - - - - - - - Phage_XkdX GHFFDFOM_01788 220668.lp_0681 8.14e-264 724.0 COG3757@1|root,COG3757@2|Bacteria,1V3SH@1239|Firmicutes,4HNR1@91061|Bacilli,3F6ZF@33958|Lactobacillaceae 91061|Bacilli M hydrolase, family 25 - - - - - - - - - - - - Glyco_hydro_25,LysM,SH3_5 GHFFDFOM_01789 220668.lp_0687 4.9e-283 778.0 2DMB7@1|root,32FWM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GHFFDFOM_01790 220668.lp_0688 5.22e-229 631.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HHHQ@91061|Bacilli,3F4MB@33958|Lactobacillaceae 91061|Bacilli F DNA/RNA non-specific endonuclease - - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 GHFFDFOM_01791 220668.lp_0689 1.46e-87 265.0 COG1525@1|root,COG1525@2|Bacteria,1V8AM@1239|Firmicutes,4IPMQ@91061|Bacilli,3F813@33958|Lactobacillaceae 91061|Bacilli L nuclease - - - - - - - - - - - - Ada_Zn_binding GHFFDFOM_01792 220668.lp_0690 0.0 1673.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli,3F3PY@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504 2.A.1.3.37 - iYO844.BG12900 DUF2156,LPG_synthase_TM GHFFDFOM_01793 220668.lp_0691 2.37e-140 395.0 COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,4HE2X@91061|Bacilli,3F5U4@33958|Lactobacillaceae 91061|Bacilli S Belongs to the LOG family yvdD - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox GHFFDFOM_01794 220668.lp_0692 2.47e-253 693.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,3F3P1@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm GHFFDFOM_01795 220668.lp_0693 0.0 1445.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,3F3XG@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN GHFFDFOM_01796 220668.lp_0694 8.42e-50 157.0 COG0695@1|root,COG0695@2|Bacteria,1VEFX@1239|Firmicutes,4HNUX@91061|Bacilli,3F874@33958|Lactobacillaceae 91061|Bacilli O Glutaredoxin nrdH - - ko:K06191 - - - - ko00000 - - - Glutaredoxin GHFFDFOM_01797 220668.lp_0695 1.11e-139 395.0 COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,4HHCA@91061|Bacilli,3F4NU@33958|Lactobacillaceae 91061|Bacilli J Methyltransferase rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS GHFFDFOM_01798 220668.lp_0696 7.57e-119 339.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,3F6IS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam GHFFDFOM_01799 220668.lp_0698 0.0 1102.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,3F3P2@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 GHFFDFOM_01800 220668.lp_0699 2.05e-62 191.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,3F7F3@33958|Lactobacillaceae 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd GHFFDFOM_01801 1136177.KCA1_0545 6.22e-140 395.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,3F4JQ@33958|Lactobacillaceae 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 GHFFDFOM_01802 220668.lp_0701 1.01e-51 163.0 2EHEM@1|root,33B6J@2|Bacteria,1VM3Z@1239|Firmicutes,4HR3I@91061|Bacilli,3F844@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2508) yaaL - - - - - - - - - - - DUF2508 GHFFDFOM_01803 220668.lp_0703 1.28e-152 429.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,3F4JR@33958|Lactobacillaceae 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin GHFFDFOM_01804 220668.lp_0704 1.39e-70 213.0 COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,3F6VW@33958|Lactobacillaceae 91061|Bacilli S Cyclic-di-AMP receptor yaaQ - - - - - - - - - - - CdAMP_rec GHFFDFOM_01805 220668.lp_0705 2.33e-239 658.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,3F50D@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C GHFFDFOM_01806 220668.lp_0706 8.46e-77 229.0 COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli,3F864@33958|Lactobacillaceae 91061|Bacilli L Involved in initiation control of chromosome replication yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - YabB GHFFDFOM_01807 220668.lp_0707 1.08e-212 587.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,3F4AI@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase GHFFDFOM_01808 220668.lp_0708 3.17e-191 530.0 COG3884@1|root,COG3884@2|Bacteria,1V3RB@1239|Firmicutes,4HHJ4@91061|Bacilli,3F41B@33958|Lactobacillaceae 91061|Bacilli I Acyl-ACP thioesterase fat - 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 - R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 - - - Acyl-ACP_TE GHFFDFOM_01809 220668.lp_0709 2.86e-245 672.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,3F3YF@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd GHFFDFOM_01810 220668.lp_0710 5.35e-270 738.0 COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,4HBFN@91061|Bacilli,3F43T@33958|Lactobacillaceae 91061|Bacilli E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily phnW - 2.6.1.37 ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 - R04152 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_5 GHFFDFOM_01811 220668.lp_0711 2.8e-187 520.0 COG0637@1|root,COG0637@2|Bacteria,1TP1A@1239|Firmicutes,4HC8X@91061|Bacilli,3F5WZ@33958|Lactobacillaceae 91061|Bacilli E Belongs to the HAD-like hydrolase superfamily. PhnX family phnX - 3.11.1.1 ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 - R00747 RC00368 ko00000,ko00001,ko01000 - - - HAD_2 GHFFDFOM_01812 220668.lp_0712 3.33e-184 514.0 COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,4HD3S@91061|Bacilli,3FB6V@33958|Lactobacillaceae 91061|Bacilli U ABC transporter permease phnE1 - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 GHFFDFOM_01813 60520.HR47_07220 6.51e-178 497.0 COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,4HDQQ@91061|Bacilli,3FB6W@33958|Lactobacillaceae 91061|Bacilli U Phosphonate ABC transporter permease phnE2 - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 GHFFDFOM_01814 220668.lp_0714 9.33e-177 493.0 COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,4HC3N@91061|Bacilli,3F3SJ@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran GHFFDFOM_01815 220668.lp_0715 2.84e-241 664.0 COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,3F3KK@33958|Lactobacillaceae 91061|Bacilli P Phosphonate ABC transporter phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd GHFFDFOM_01816 220668.lp_0717 6.84e-167 467.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,3F3WV@33958|Lactobacillaceae 91061|Bacilli O Universal bacterial protein YeaZ yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 GHFFDFOM_01817 220668.lp_0718 4.66e-131 372.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,3F522@33958|Lactobacillaceae 91061|Bacilli K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 GHFFDFOM_01818 220668.lp_0720 5.74e-108 310.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HP50@91061|Bacilli,3F6PY@33958|Lactobacillaceae 91061|Bacilli K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 GHFFDFOM_01819 220668.lp_0721 1.26e-249 685.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,3F4AX@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 GHFFDFOM_01820 220668.lp_0723 0.0 1184.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,3F3QI@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn GHFFDFOM_01821 220668.lp_0725 3.67e-154 433.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,3F40G@33958|Lactobacillaceae 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N GHFFDFOM_01822 220668.lp_0726 2.38e-140 397.0 COG1266@1|root,COG1266@2|Bacteria,1UZGJ@1239|Firmicutes,4HFCB@91061|Bacilli,3F5JU@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity ydiL - - ko:K07052 - - - - ko00000 - - - Abi GHFFDFOM_01823 220668.lp_0727 9.82e-55 171.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,3F7CZ@33958|Lactobacillaceae 91061|Bacilli O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 GHFFDFOM_01824 220668.lp_0728 0.0 1011.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,3F3MM@33958|Lactobacillaceae 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 GHFFDFOM_01825 220668.lp_0729 0.0 1150.0 COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,4HAZH@91061|Bacilli,3F44Y@33958|Lactobacillaceae 91061|Bacilli E amino acid ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 GHFFDFOM_01826 220668.lp_0730 7.29e-247 679.0 COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli,3F4JV@33958|Lactobacillaceae 91061|Bacilli M transferase tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 GHFFDFOM_01827 220668.lp_0733 6.57e-199 553.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,3F4ER@33958|Lactobacillaceae 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 GHFFDFOM_01828 220668.lp_0734 3.7e-149 420.0 COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli,3F3SQ@33958|Lactobacillaceae 91061|Bacilli S YigZ family yvyE - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - DUF1949,UPF0029 GHFFDFOM_01829 220668.lp_0735 0.0 899.0 COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli,3F3TQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K02240 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1 - - DEAD,Helicase_C,ResIII GHFFDFOM_01830 220668.lp_0736 2.94e-164 459.0 COG1040@1|root,COG1040@2|Bacteria,1V73S@1239|Firmicutes,4HJ6R@91061|Bacilli,3F714@33958|Lactobacillaceae 91061|Bacilli S Competence protein comFC - - ko:K02242 - M00429 - - ko00000,ko00002,ko02044 - - - Pribosyltran GHFFDFOM_01831 1136177.KCA1_0576 1.27e-129 368.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,3F40M@33958|Lactobacillaceae 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE GHFFDFOM_01832 220668.lp_0739 0.0 1543.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,3F4DH@33958|Lactobacillaceae 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SecA_DEAD,SecA_PP_bind,SecA_SW GHFFDFOM_01833 220668.lp_0741 1.69e-257 706.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,3F3SN@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 GHFFDFOM_01834 220668.lp_0742 1.28e-276 757.0 COG0265@1|root,COG0265@2|Bacteria,1TSBA@1239|Firmicutes,4HA05@91061|Bacilli,3F4TP@33958|Lactobacillaceae 91061|Bacilli O Domain present in PSD-95, Dlg, and ZO-1/2. minJ - - - - - - - - - - - PDZ_2 GHFFDFOM_01835 220668.lp_0743 1.49e-170 476.0 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,3FC91@33958|Lactobacillaceae 91061|Bacilli K response regulator phoP - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C GHFFDFOM_01836 220668.lp_0744 0.0 868.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,3F3W2@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like GHFFDFOM_01837 220668.lp_0746 6.91e-201 557.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,3F4ER@33958|Lactobacillaceae 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 GHFFDFOM_01838 220668.lp_0747 2.22e-206 572.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,3F3NI@33958|Lactobacillaceae 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 GHFFDFOM_01839 220668.lp_0748 5.04e-200 555.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,3F412@33958|Lactobacillaceae 91061|Bacilli P Phosphate transport system permease protein PstA pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 GHFFDFOM_01840 220668.lp_0749 9.78e-190 527.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB2 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran GHFFDFOM_01841 220668.lp_0750 2.31e-179 499.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB1 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran GHFFDFOM_01842 220668.lp_0751 1.55e-150 424.0 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,3F46W@33958|Lactobacillaceae 91061|Bacilli P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU GHFFDFOM_01843 220668.lp_0752 2.78e-65 199.0 COG1983@1|root,COG1983@2|Bacteria 2|Bacteria KT positive regulation of macromolecule biosynthetic process pspC - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC GHFFDFOM_01844 220668.lp_0753 2.87e-71 215.0 COG1950@1|root,COG1950@2|Bacteria,1VF4I@1239|Firmicutes,4HNXP@91061|Bacilli,3F7IN@33958|Lactobacillaceae 91061|Bacilli S Mycobacterial 4 TMS phage holin, superfamily IV yvlD - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 GHFFDFOM_01845 220668.lp_0754 2.55e-225 622.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,3F3Z3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N GHFFDFOM_01846 220668.lp_0755 1.04e-211 583.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,3F42N@33958|Lactobacillaceae 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT GHFFDFOM_01847 220668.lp_0756 1.15e-234 646.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,3F4C8@33958|Lactobacillaceae 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N GHFFDFOM_01848 220668.lp_0757 1.13e-218 603.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,3F45A@33958|Lactobacillaceae 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase GHFFDFOM_01849 220668.lp_0758 6.37e-160 448.0 COG2200@1|root,COG2200@2|Bacteria,1TVGR@1239|Firmicutes,4I2JH@91061|Bacilli,3F5N3@33958|Lactobacillaceae 91061|Bacilli T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL GHFFDFOM_01850 220668.lp_0760 0.0 939.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase nox - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim GHFFDFOM_01851 1136177.KCA1_0597 2.24e-207 580.0 COG3405@1|root,COG3405@2|Bacteria,1V4ZT@1239|Firmicutes,4HG8R@91061|Bacilli,3F5GF@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 8 (cellulase D) family ydaJ - - - - - - - - - - - Glyco_hydro_8 GHFFDFOM_01852 1136177.KCA1_0598 5.76e-309 848.0 28NCT@1|root,2ZBFR@2|Bacteria,1UKIC@1239|Firmicutes,4HF21@91061|Bacilli,3F5BU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01853 1136177.KCA1_0599 2.39e-256 717.0 COG5298@1|root,COG5298@2|Bacteria,1V2SR@1239|Firmicutes,4HG5T@91061|Bacilli,3F58K@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria - - - - - - - - - - - - DUF2334 GHFFDFOM_01854 1136177.KCA1_0600 2.74e-277 761.0 COG1215@1|root,COG1215@2|Bacteria,1TRCI@1239|Firmicutes,4HAAK@91061|Bacilli,3FC1R@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family group 2 ydaM - - - - - - - - - - - Glyco_tranf_2_3 GHFFDFOM_01855 1136177.KCA1_0601 0.0 1106.0 28HGC@1|root,2Z7S8@2|Bacteria,1V0RQ@1239|Firmicutes,4HF26@91061|Bacilli,3F5HU@33958|Lactobacillaceae 91061|Bacilli S Bacterial cellulose synthase subunit - - - - - - - - - - - - BcsB GHFFDFOM_01856 1136177.KCA1_0602 7.91e-172 483.0 COG2199@1|root,COG2199@2|Bacteria,1UMTY@1239|Firmicutes,4IU07@91061|Bacilli,3FB9S@33958|Lactobacillaceae 91061|Bacilli T diguanylate cyclase activity - - - - - - - - - - - - - GHFFDFOM_01857 220668.lp_0761 8.65e-226 622.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,3F411@33958|Lactobacillaceae 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 GHFFDFOM_01858 220668.lp_0762 4.31e-141 399.0 COG2323@1|root,COG2323@2|Bacteria,1TPNF@1239|Firmicutes,4HF15@91061|Bacilli,3F4F3@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF421) yviA - - - - - - - - - - - DUF421 GHFFDFOM_01859 220668.lp_0763 7.54e-99 287.0 2C9NT@1|root,32ZGB@2|Bacteria,1VG8C@1239|Firmicutes,4HN0V@91061|Bacilli,3F749@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3290) - - - - - - - - - - - - DUF3290 GHFFDFOM_01860 220668.lp_0764 0.0 1135.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,3F457@33958|Lactobacillaceae 91061|Bacilli G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV GHFFDFOM_01861 220668.lp_0765 5.9e-170 474.0 COG2200@1|root,COG2200@2|Bacteria,1V6YK@1239|Firmicutes,4HIIM@91061|Bacilli,3F5HI@33958|Lactobacillaceae 91061|Bacilli T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL GHFFDFOM_01862 220668.lp_0766 0.0 900.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4IEVM@91061|Bacilli,3F4KS@33958|Lactobacillaceae 91061|Bacilli S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain nox2 - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim GHFFDFOM_01863 220668.lp_0769 4.63e-135 382.0 COG2173@1|root,COG2173@2|Bacteria,1VAFK@1239|Firmicutes,4HS7K@91061|Bacilli,3F4HX@33958|Lactobacillaceae 91061|Bacilli E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide aad - 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - Peptidase_M15 GHFFDFOM_01864 220668.lp_0770 5.33e-268 736.0 COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,3F4X1@33958|Lactobacillaceae 91061|Bacilli EGP transporter blt - - ko:K08153 - M00717 - - ko00000,ko00002,ko02000 2.A.1.2.8 - - MFS_1 GHFFDFOM_01865 220668.lp_0771 9.45e-152 426.0 COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,4HA8H@91061|Bacilli,3F4RZ@33958|Lactobacillaceae 91061|Bacilli S HD containing hydrolase-like enzyme yfbR - - ko:K07023 - - - - ko00000 - - - HD_2 GHFFDFOM_01866 220668.lp_0772 0.0 1306.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,3F3XM@33958|Lactobacillaceae 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB GHFFDFOM_01867 220668.lp_0773 0.0 1884.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,3F4TZ@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran GHFFDFOM_01868 220668.lp_0774 2.21e-113 325.0 COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,4HFPR@91061|Bacilli,3F4W2@33958|Lactobacillaceae 91061|Bacilli H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS GHFFDFOM_01869 220668.lp_0775 7.5e-302 822.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,3F46X@33958|Lactobacillaceae 91061|Bacilli E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04675 Arginosuc_synth GHFFDFOM_01870 220668.lp_0776 0.0 909.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,3F4PF@33958|Lactobacillaceae 91061|Bacilli E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 GHFFDFOM_01871 220668.lp_0778 8.62e-114 327.0 COG3247@1|root,COG3247@2|Bacteria,1VJ0U@1239|Firmicutes,4HQJ0@91061|Bacilli,3FB5N@33958|Lactobacillaceae 91061|Bacilli S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 GHFFDFOM_01872 220668.lp_0779 1.71e-207 574.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli,3F4NY@33958|Lactobacillaceae 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 GHFFDFOM_01873 220668.lp_0780 4.56e-243 667.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,3F4D5@33958|Lactobacillaceae 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 GHFFDFOM_01874 220668.lp_0781 1.21e-215 596.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,3F4AB@33958|Lactobacillaceae 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N GHFFDFOM_01875 220668.lp_0783 0.0 1038.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GHFFDFOM_01876 220668.lp_0785 1.55e-225 622.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,3F4Z6@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C GHFFDFOM_01877 220668.lp_0786 5.11e-133 377.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,3F3M0@33958|Lactobacillaceae 91061|Bacilli O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease GHFFDFOM_01879 220668.lp_0787 1.14e-311 850.0 COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,3F4R8@33958|Lactobacillaceae 91061|Bacilli K Sigma-54 factor, core binding domain rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD GHFFDFOM_01880 220668.lp_0788 5.75e-242 665.0 COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,4HAE6@91061|Bacilli,3F53Y@33958|Lactobacillaceae 91061|Bacilli K Putative sugar-binding domain cggR - - ko:K05311 - - - - ko00000,ko03000 - - - Sugar-bind GHFFDFOM_01881 220668.lp_0789 2.02e-245 674.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,3F3JS@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N GHFFDFOM_01882 220668.lp_0790 1.31e-285 780.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,3F3SC@33958|Lactobacillaceae 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK GHFFDFOM_01883 220668.lp_0791 7.15e-179 498.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,3F494@33958|Lactobacillaceae 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM GHFFDFOM_01884 220668.lp_0792 0.0 866.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,3F3JP@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N GHFFDFOM_01885 220668.lp_0793 8.46e-170 476.0 29WGZ@1|root,30I32@2|Bacteria,1U5IR@1239|Firmicutes,4IF9H@91061|Bacilli,3F61Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01886 220668.lp_0794 0.0 1001.0 COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F3MU@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC GHFFDFOM_01887 220668.lp_0795 1.76e-43 142.0 COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli,3F7IQ@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase secG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG GHFFDFOM_01888 220668.lp_0796 6.62e-180 500.0 COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4HBE6@91061|Bacilli,3F5XW@33958|Lactobacillaceae 91061|Bacilli S Serine aminopeptidase, S33 est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 GHFFDFOM_01889 220668.lp_0797 0.0 1465.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,3F4EC@33958|Lactobacillaceae 91061|Bacilli J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 GHFFDFOM_01890 220668.lp_0799 2.4e-107 309.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,3F65B@33958|Lactobacillaceae 91061|Bacilli J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB GHFFDFOM_01891 220668.lp_0800 0.0 3065.0 COG3209@1|root,COG4886@1|root,COG3209@2|Bacteria,COG4886@2|Bacteria,1TT3P@1239|Firmicutes,4I28K@91061|Bacilli,3F4YY@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF5011) - - - - - - - - - - - - Big_3,DUF285,Gram_pos_anchor GHFFDFOM_01892 220668.lp_0802 0.0 911.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli,3F4HA@33958|Lactobacillaceae 91061|Bacilli P ABC transporter glnP - - ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1,SBP_bac_3 GHFFDFOM_01893 60520.HR47_07585 9.36e-171 477.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran GHFFDFOM_01894 220668.lp_0804 5.62e-137 387.0 COG4894@1|root,COG4894@2|Bacteria,1V8EY@1239|Firmicutes,4HMMS@91061|Bacilli,3F698@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - LOR GHFFDFOM_01895 220668.lp_0805 1.98e-199 553.0 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,3F58Y@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase ycsE - - - - - - - - - - - Hydrolase_3 GHFFDFOM_01896 220668.lp_0806 5.71e-174 484.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,3F3W0@33958|Lactobacillaceae 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG GHFFDFOM_01897 220668.lp_0807 3.52e-227 626.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli,3F3MW@33958|Lactobacillaceae 91061|Bacilli C phosphate acetyltransferase pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB GHFFDFOM_01898 220668.lp_0809 1.07e-104 302.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,3F3MR@33958|Lactobacillaceae 91061|Bacilli O Hydrolase, P-loop family ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE GHFFDFOM_01899 220668.lp_0810 2.52e-114 328.0 COG1670@1|root,COG1670@2|Bacteria,1UI5U@1239|Firmicutes,4ISEP@91061|Bacilli,3FBSC@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 GHFFDFOM_01900 220668.lp_0811 7.18e-131 370.0 COG0847@1|root,COG0847@2|Bacteria,1V57H@1239|Firmicutes,4HI1V@91061|Bacilli,3F42Z@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T GHFFDFOM_01901 220668.lp_0812 1.46e-197 545.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli,3F4GK@33958|Lactobacillaceae 91061|Bacilli L exodeoxyribonuclease III exoA GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos GHFFDFOM_01902 220668.lp_0813 1.26e-212 587.0 COG0673@1|root,COG0673@2|Bacteria,1UZRV@1239|Firmicutes,4HEWB@91061|Bacilli,3F4BX@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold ysjB - - ko:K03810 - - - - ko00000 - - - GFO_IDH_MocA GHFFDFOM_01903 220668.lp_0814 6.24e-214 591.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,3F40T@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C GHFFDFOM_01904 220668.lp_0815 0.0 1306.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter yvgP GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger GHFFDFOM_01905 220668.lp_0816 3.07e-119 340.0 COG1846@1|root,COG1846@2|Bacteria,1U5EC@1239|Firmicutes,4IF5S@91061|Bacilli,3F5QD@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR_2 GHFFDFOM_01906 220668.lp_0817 6.9e-157 440.0 COG4330@1|root,COG4330@2|Bacteria,1VFQS@1239|Firmicutes,4HNWH@91061|Bacilli,3F5AV@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1361) - - - - - - - - - - - - DUF1361 GHFFDFOM_01907 220668.lp_0818 8.33e-192 533.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,3F4N3@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N GHFFDFOM_01908 220668.lp_0819 2.18e-182 513.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,3F41C@33958|Lactobacillaceae 91061|Bacilli S YbbR-like protein ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR GHFFDFOM_01909 220668.lp_0820 0.0 871.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,3F3W5@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSB619.SA_RS11275 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV GHFFDFOM_01910 220668.lp_0822 0.0 1166.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,3F467@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS GHFFDFOM_01911 220668.lp_0823 5.44e-159 445.0 COG2200@1|root,COG2200@2|Bacteria,1U6DK@1239|Firmicutes,4IG5B@91061|Bacilli,3F7NQ@33958|Lactobacillaceae 91061|Bacilli T EAL domain - - - - - - - - - - - - EAL GHFFDFOM_01912 220668.lp_0824 4.46e-187 520.0 COG0561@1|root,COG0561@2|Bacteria,1TVJM@1239|Firmicutes,4I37C@91061|Bacilli,3F5I5@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - 3.1.3.23 ko:K07757 - - R00804 - ko00000,ko01000 - - - Hydrolase_3 GHFFDFOM_01913 220668.lp_0825 4.22e-136 385.0 COG1309@1|root,COG1309@2|Bacteria,1VH11@1239|Firmicutes,4IEW1@91061|Bacilli,3F4NX@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GHFFDFOM_01914 220668.lp_0826 1.46e-263 720.0 COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,4HADZ@91061|Bacilli,3F48R@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of alpha and beta anomers of maltose galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim GHFFDFOM_01915 220668.lp_0827 3.38e-70 211.0 2C26E@1|root,3424N@2|Bacteria,1VX4A@1239|Firmicutes,4HXT9@91061|Bacilli,3F70Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01916 220668.lp_0828 2.05e-94 275.0 29P38@1|root,30A1E@2|Bacteria,1U62H@1239|Firmicutes,4IFRM@91061|Bacilli,3F6VJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01917 220668.lp_0829 1.17e-167 469.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,3F4IY@33958|Lactobacillaceae 91061|Bacilli C nitroreductase nfrA - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase GHFFDFOM_01918 220668.lp_0830 5.77e-177 494.0 COG0477@1|root,COG2814@2|Bacteria,1UI2A@1239|Firmicutes,4ISBQ@91061|Bacilli 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 GHFFDFOM_01919 1136177.KCA1_0666 1.15e-41 148.0 COG2211@1|root,COG2211@2|Bacteria,1UJB6@1239|Firmicutes 1239|Firmicutes G Transmembrane secretion effector - - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1 GHFFDFOM_01920 220668.lp_0834 0.0 1021.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,3F3WI@33958|Lactobacillaceae 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N GHFFDFOM_01921 220668.lp_0835 6.37e-186 516.0 2CBBX@1|root,309KW@2|Bacteria,1W4RS@1239|Firmicutes,4IF26@91061|Bacilli,3F61U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01923 220668.lp_0836 5.45e-94 274.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4IFFY@91061|Bacilli,3F6DX@33958|Lactobacillaceae 91061|Bacilli P ArsC family spx1 - - ko:K16509 - - - - ko00000 - - - ArsC GHFFDFOM_01924 220668.lp_0837 3.88e-46 148.0 29PGP@1|root,30AEU@2|Bacteria,1U6JS@1239|Firmicutes,4IGC9@91061|Bacilli,3F81T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01925 220668.lp_0838 2.08e-117 336.0 COG4767@1|root,COG4767@2|Bacteria,1VKIA@1239|Firmicutes,4HNUJ@91061|Bacilli,3F86G@33958|Lactobacillaceae 91061|Bacilli V VanZ like family - - - - - - - - - - - - VanZ GHFFDFOM_01926 220668.lp_0840 1.06e-314 860.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 GHFFDFOM_01927 220668.lp_0841 4.45e-226 623.0 COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,4HAQS@91061|Bacilli,3F3SR@33958|Lactobacillaceae 91061|Bacilli FP exopolyphosphatase ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA GHFFDFOM_01928 220668.lp_0842 0.0 1424.0 COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,4HA88@91061|Bacilli,3F3PE@33958|Lactobacillaceae 91061|Bacilli P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N GHFFDFOM_01929 220668.lp_0843 0.0 996.0 COG0248@1|root,COG0248@2|Bacteria,1VT8Q@1239|Firmicutes,4HB84@91061|Bacilli,3F49N@33958|Lactobacillaceae 91061|Bacilli FP exopolyphosphatase ppx3 - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA GHFFDFOM_01930 220668.lp_0844 6.68e-197 545.0 COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,4HKCY@91061|Bacilli,3F4GV@33958|Lactobacillaceae 91061|Bacilli M LicD family licD - - ko:K07271 - - - - ko00000,ko01000 - - - LicD GHFFDFOM_01931 220668.lp_0845 6.16e-107 308.0 COG1846@1|root,COG1846@2|Bacteria,1V6TR@1239|Firmicutes,4HXA8@91061|Bacilli,3F66M@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - MarR,MarR_2 GHFFDFOM_01932 220668.lp_0846 1.36e-27 100.0 29PP3@1|root,30AM9@2|Bacteria,1U6UM@1239|Firmicutes,4IGNF@91061|Bacilli,3F8IE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01933 220668.lp_0848 1.79e-287 788.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,3F44D@33958|Lactobacillaceae 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease GHFFDFOM_01934 220668.lp_0849 0.0 1156.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family pox1 - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GHFFDFOM_01935 220668.lp_0850 3.3e-199 552.0 COG0196@1|root,COG0196@2|Bacteria,1V8DX@1239|Firmicutes,4HITY@91061|Bacilli,3F6IA@33958|Lactobacillaceae 91061|Bacilli H Belongs to the ribF family ribC1 - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn GHFFDFOM_01936 220668.lp_0852 0.0 1176.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family pox2 - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GHFFDFOM_01937 220668.lp_0853 6.37e-232 636.0 COG2267@1|root,COG2267@2|Bacteria,1UEDT@1239|Firmicutes,4HF61@91061|Bacilli,3F47H@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates pepR - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 GHFFDFOM_01938 220668.lp_0854 1.23e-229 633.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,3F5HY@33958|Lactobacillaceae 91061|Bacilli H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 GHFFDFOM_01939 220668.lp_0856 0.0 1229.0 COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli,3F3WT@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase oatA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - - - - - - - - - - Acyl_transf_3 GHFFDFOM_01940 220668.lp_0857 0.0 1651.0 COG2936@1|root,COG2936@2|Bacteria,1TT78@1239|Firmicutes,4HBA0@91061|Bacilli,3F44E@33958|Lactobacillaceae 91061|Bacilli E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline pepX - 3.4.14.11 ko:K01281 - - - - ko00000,ko01000,ko01002 - - - PepX_C,PepX_N,Peptidase_S15 GHFFDFOM_01941 220668.lp_0858 1.89e-90 265.0 COG1764@1|root,COG1764@2|Bacteria,1VY9T@1239|Firmicutes,4HXI7@91061|Bacilli,3F7CX@33958|Lactobacillaceae 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC GHFFDFOM_01942 220668.lp_0860 1.21e-63 194.0 29PTD@1|root,30ARJ@2|Bacteria,1U70S@1239|Firmicutes,4IGV3@91061|Bacilli,3F8TP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01943 220668.lp_0861 0.0 871.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F3QY@33958|Lactobacillaceae 91061|Bacilli E Amino Acid yhdG - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 GHFFDFOM_01944 220668.lp_0862 6.12e-115 328.0 2DPIQ@1|root,3328X@2|Bacteria,1VFYC@1239|Firmicutes,4HNHQ@91061|Bacilli,3F5FA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - AP2 GHFFDFOM_01945 220668.lp_0863 5.24e-191 530.0 COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli,3F3V7@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin GHFFDFOM_01946 220668.lp_0864 7.48e-96 279.0 COG1051@1|root,COG1051@2|Bacteria,1VED7@1239|Firmicutes,4HRPV@91061|Bacilli,3FBDM@33958|Lactobacillaceae 91061|Bacilli F Nudix hydrolase - - - - - - - - - - - - NUDIX GHFFDFOM_01947 220668.lp_0865 1.48e-27 99.8 290AM@1|root,2ZN07@2|Bacteria,1W23H@1239|Firmicutes,4I028@91061|Bacilli,3F8TR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01948 220668.lp_0866 6.02e-135 382.0 COG0194@1|root,COG0194@2|Bacteria,1V8PW@1239|Firmicutes,4HJCB@91061|Bacilli,3F6N3@33958|Lactobacillaceae 91061|Bacilli F Guanylate kinase gmk2 - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin GHFFDFOM_01949 220668.lp_0868 2.02e-106 306.0 COG0735@1|root,COG0735@2|Bacteria,1V6RI@1239|Firmicutes,4HIGM@91061|Bacilli,3F6W3@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Fur family zur - - ko:K02076,ko:K03711 - - - - ko00000,ko03000 - - - FUR GHFFDFOM_01950 220668.lp_0869 8.84e-18 83.2 2EQI3@1|root,33I43@2|Bacteria,1VN2E@1239|Firmicutes,4HR4S@91061|Bacilli,3F860@33958|Lactobacillaceae 91061|Bacilli - - - - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - - GHFFDFOM_01951 220668.lp_0871 1.01e-188 525.0 2C6F0@1|root,32RH8@2|Bacteria,1V7ET@1239|Firmicutes,4HJDI@91061|Bacilli,3F4UC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01952 220668.lp_0872 6.94e-146 411.0 COG0546@1|root,COG0546@2|Bacteria,1V7U6@1239|Firmicutes,4HJ9I@91061|Bacilli,3F658@33958|Lactobacillaceae 91061|Bacilli S HAD hydrolase, family IA, variant gph1 - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 GHFFDFOM_01953 60520.HR47_04950 3.21e-268 736.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspC - 2.6.1.57 ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 M00024,M00025,M00034,M00040,M00525 R00694,R00734,R01731,R04467,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GHFFDFOM_01954 60520.HR47_04955 1.03e-217 603.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HCIS@91061|Bacilli,3F4US@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhD - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C GHFFDFOM_01955 220668.lp_0875 5.2e-54 169.0 2900D@1|root,2ZMQP@2|Bacteria,1W1YJ@1239|Firmicutes,4I01F@91061|Bacilli,3F8BQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01957 220668.lp_0878 2.3e-172 481.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - - ko:K10041 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran GHFFDFOM_01958 220668.lp_0881 3.39e-190 529.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli,3F4GG@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein glnH - - ko:K10039 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 GHFFDFOM_01959 220668.lp_0882 3.14e-140 397.0 COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HFBH@91061|Bacilli,3F3XW@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnM GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 GHFFDFOM_01960 220668.lp_0883 1.27e-141 401.0 COG0765@1|root,COG0765@2|Bacteria,1UJM4@1239|Firmicutes,4HBAS@91061|Bacilli,3F3WJ@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 GHFFDFOM_01961 220668.lp_0884 3.49e-108 312.0 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4I276@91061|Bacilli,3F7QW@33958|Lactobacillaceae 91061|Bacilli G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 - - - ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 - - PTS_EIIA_1 GHFFDFOM_01962 220668.lp_0885 1.57e-196 545.0 COG3711@1|root,COG3711@2|Bacteria,1TS07@1239|Firmicutes,4HUBU@91061|Bacilli,3F40C@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain - - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD GHFFDFOM_01963 220668.lp_0886 0.0 919.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HEWK@91061|Bacilli,3F4YU@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system, EIIB - - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIB,PTS_EIIC GHFFDFOM_01964 220668.lp_0887 4.31e-180 501.0 COG3394@1|root,COG3394@2|Bacteria,1V4IM@1239|Firmicutes,4HG4E@91061|Bacilli,3F5B7@33958|Lactobacillaceae 91061|Bacilli G YdjC-like protein - - 3.5.1.105 ko:K03478 - - - - ko00000,ko01000 - - - YdjC GHFFDFOM_01965 220668.lp_0888 0.0 864.0 COG0531@1|root,COG0531@2|Bacteria,1TQ48@1239|Firmicutes,4HBGT@91061|Bacilli,3F3YJ@33958|Lactobacillaceae 91061|Bacilli E amino acid steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 GHFFDFOM_01966 220668.lp_0889 2.55e-95 278.0 COG1846@1|root,COG1846@2|Bacteria,1TTKG@1239|Firmicutes,4I358@91061|Bacilli,3F6NM@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR GHFFDFOM_01967 220668.lp_0891 8.87e-191 531.0 COG0730@1|root,COG0730@2|Bacteria,1TQ8H@1239|Firmicutes,4IIWY@91061|Bacilli,3F4A6@33958|Lactobacillaceae 91061|Bacilli S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE GHFFDFOM_01968 220668.lp_0892 3.08e-93 273.0 COG1846@1|root,COG1846@2|Bacteria,1U6HM@1239|Firmicutes,4IG9X@91061|Bacilli,3F7XV@33958|Lactobacillaceae 91061|Bacilli K MarR family - - - - - - - - - - - - MarR_2 GHFFDFOM_01969 220668.lp_0893 3.22e-269 738.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,3FB93@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr GHFFDFOM_01970 220668.lp_0894 2.93e-109 318.0 COG0730@1|root,COG0730@2|Bacteria,1V75K@1239|Firmicutes,4HEE8@91061|Bacilli,3F6BU@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE GHFFDFOM_01971 220668.lp_0895 1.81e-128 365.0 COG1309@1|root,COG1309@2|Bacteria,1V847@1239|Firmicutes,4HI2V@91061|Bacilli,3F760@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GHFFDFOM_01972 220668.lp_0896 5.95e-300 819.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,3F4B2@33958|Lactobacillaceae 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 GHFFDFOM_01973 220668.lp_0897 4.6e-102 295.0 COG1051@1|root,COG1051@2|Bacteria,1V5NQ@1239|Firmicutes,4HH6Z@91061|Bacilli,3F66V@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain rppH3 - - - - - - - - - - - NUDIX GHFFDFOM_01974 220668.lp_0898 3.5e-64 196.0 COG2076@1|root,COG2076@2|Bacteria,1VEZX@1239|Firmicutes,4HKXB@91061|Bacilli,3F7D6@33958|Lactobacillaceae 91061|Bacilli U Multidrug resistance protein sugE - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res GHFFDFOM_01975 220668.lp_0899 1.61e-36 123.0 28RTF@1|root,2ZE5S@2|Bacteria,1W5SB@1239|Firmicutes,4HZIY@91061|Bacilli,3F873@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01976 220668.lp_0900 6.4e-164 458.0 COG0406@1|root,COG0406@2|Bacteria,1TQWQ@1239|Firmicutes,4HFDZ@91061|Bacilli,3F5XR@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family pgm3 - - - - - - - - - - - His_Phos_1 GHFFDFOM_01977 220668.lp_0901 1.2e-160 449.0 COG0406@1|root,COG0406@2|Bacteria,1TQWQ@1239|Firmicutes,4HF2N@91061|Bacilli,3F524@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family gpm2 - - - - - - - - - - - His_Phos_1 GHFFDFOM_01978 220668.lp_0902 0.0 1142.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,4H9Q5@91061|Bacilli,3F4AZ@33958|Lactobacillaceae 91061|Bacilli P TrkA C-terminal domain protein yjbQ - - ko:K03455,ko:K03499 - - - - ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 - - Na_H_Exchanger,TrkA_C,TrkA_N GHFFDFOM_01979 220668.lp_0903 1.39e-225 623.0 COG1051@1|root,COG2320@1|root,COG1051@2|Bacteria,COG2320@2|Bacteria,1VFYN@1239|Firmicutes,4IPPU@91061|Bacilli,3FBDN@33958|Lactobacillaceae 91061|Bacilli F Belongs to the Nudix hydrolase family - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - GrpB,NUDIX GHFFDFOM_01980 60520.HR47_05080 2.23e-143 405.0 COG0586@1|root,COG0586@2|Bacteria,1UZ4P@1239|Firmicutes,4HG3F@91061|Bacilli,3F51Q@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein - - - ko:K03975 - - - - ko00000 - - - SNARE_assoc GHFFDFOM_01981 220668.lp_0910 0.0 1474.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,3F486@33958|Lactobacillaceae 91061|Bacilli L DNA helicase helD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 GHFFDFOM_01982 220668.lp_0912 8.45e-211 583.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,3F4PC@33958|Lactobacillaceae 91061|Bacilli S Nitronate monooxygenase fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO GHFFDFOM_01983 220668.lp_0913 1.22e-227 626.0 COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli,3F42Q@33958|Lactobacillaceae 91061|Bacilli F Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK GHFFDFOM_01984 220668.lp_0914 0.0 1038.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,3F3NV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase GHFFDFOM_01985 220668.lp_0915 1.08e-71 216.0 2E9BR@1|root,333JH@2|Bacteria,1VI51@1239|Firmicutes,4HQRQ@91061|Bacilli,3F6MA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF4064 GHFFDFOM_01986 220668.lp_0917 5.57e-83 245.0 COG1396@1|root,COG1396@2|Bacteria,1UUX6@1239|Firmicutes,4IFVS@91061|Bacilli,3F751@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 GHFFDFOM_01987 220668.lp_0918 0.0 1944.0 COG1112@1|root,COG1112@2|Bacteria,1TQCB@1239|Firmicutes,4HBDJ@91061|Bacilli,3F4YB@33958|Lactobacillaceae 91061|Bacilli L AAA domain - - - - - - - - - - - - AAA_11,AAA_12,PLDc_2,Viral_helicase1 GHFFDFOM_01988 220668.lp_0919 1.36e-147 417.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity XK27_07075 - - ko:K07052 - - - - ko00000 - - - Abi GHFFDFOM_01989 220668.lp_0923 1.51e-295 840.0 COG2340@1|root,COG2340@2|Bacteria,1U59T@1239|Firmicutes,4IF1C@91061|Bacilli,3F5B3@33958|Lactobacillaceae 91061|Bacilli S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP,Gram_pos_anchor,SLAP GHFFDFOM_01990 1136177.KCA1_0740 1.59e-64 197.0 COG1396@1|root,COG1396@2|Bacteria,1UI5S@1239|Firmicutes,4I3Y0@91061|Bacilli,3F7G6@33958|Lactobacillaceae 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 GHFFDFOM_01991 1136177.KCA1_0741 4.45e-116 383.0 COG1196@1|root,COG1196@2|Bacteria,1W39C@1239|Firmicutes,4I0DV@91061|Bacilli,3F754@33958|Lactobacillaceae 91061|Bacilli D nuclear chromosome segregation - - - - - - - - - - - - Gram_pos_anchor GHFFDFOM_01992 60520.HR47_05145 1.45e-107 313.0 29P6N@1|root,30A4S@2|Bacteria,1U672@1239|Firmicutes,4IFXM@91061|Bacilli,3F789@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01993 60520.HR47_05150 2.25e-204 571.0 29W71@1|root,30HS8@2|Bacteria,1VZSI@1239|Firmicutes,4IEVP@91061|Bacilli,3F4M9@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4767) - - - - - - - - - - - - DUF4767 GHFFDFOM_01994 60520.HR47_05155 6.35e-69 209.0 2AHKB@1|root,317Y4@2|Bacteria,1U7PK@1239|Firmicutes,4IHKX@91061|Bacilli,3F9ZG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01995 220668.lp_0924 3.61e-61 190.0 COG4642@1|root,COG4642@2|Bacteria,1UUX7@1239|Firmicutes,4I4CE@91061|Bacilli,3F6H6@33958|Lactobacillaceae 91061|Bacilli S MORN repeat - - - - - - - - - - - - MORN GHFFDFOM_01996 220668.lp_0925 0.0 1167.0 COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,1U6DU@1239|Firmicutes,4H9XT@91061|Bacilli,3F3MH@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase family XK27_09800 - - - - - - - - - - - Acyl_transf_3 GHFFDFOM_01997 220668.lp_0926 1.81e-50 160.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein ydaS - - - - - - - - - - - Transgly_assoc GHFFDFOM_01998 220668.lp_0927 1.95e-116 334.0 29VKQ@1|root,30H3Q@2|Bacteria,1UH2V@1239|Firmicutes,4IFA9@91061|Bacilli,3F633@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_01999 220668.lp_0928 5.74e-32 111.0 29PNK@1|root,30AKT@2|Bacteria,1U6U3@1239|Firmicutes,4IGMX@91061|Bacilli,3F8HM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02000 220668.lp_0929 1.1e-93 273.0 COG1302@1|root,COG1302@2|Bacteria,1V8FM@1239|Firmicutes,4HJ0H@91061|Bacilli,3F77J@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function asp1 - - - - - - - - - - - Asp23 GHFFDFOM_02001 220668.lp_0930 1.04e-94 276.0 COG1302@1|root,COG1302@2|Bacteria,1VJRA@1239|Firmicutes,4HXJN@91061|Bacilli,3F692@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function asp2 - - - - - - - - - - - Asp23 GHFFDFOM_02002 220668.lp_0931 4.56e-189 525.0 COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,3F585@33958|Lactobacillaceae 91061|Bacilli Q Fumarylacetoacetate (FAA) hydrolase family yisK - 3.7.1.5,4.1.1.68 ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 M00533 R01085,R04134,R04380 RC00326,RC00446,RC01085,RC02669 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase GHFFDFOM_02003 220668.lp_0932 3.1e-217 601.0 2DMBI@1|root,32H42@2|Bacteria,1VFT3@1239|Firmicutes,4HK1A@91061|Bacilli,3F7XU@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4767) yjdB - - - - - - - - - - - DUF4767 GHFFDFOM_02004 220668.lp_0934 2.3e-65 199.0 COG1447@1|root,COG1447@2|Bacteria,1U69A@1239|Firmicutes,4IG0F@91061|Bacilli,3F7CF@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit - - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA GHFFDFOM_02005 220668.lp_0935 1.22e-137 389.0 COG3408@1|root,COG3408@2|Bacteria,1TWD3@1239|Firmicutes,4I54S@91061|Bacilli,3F54W@33958|Lactobacillaceae 91061|Bacilli G Glycogen debranching enzyme - - - - - - - - - - - - - GHFFDFOM_02006 220668.lp_0937 0.0 1674.0 COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli,3F3UH@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 GHFFDFOM_02007 220668.lp_0938 0.0 1889.0 COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,4HB5A@91061|Bacilli,3F50Q@33958|Lactobacillaceae 91061|Bacilli V Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - EcoR124_C,HSDR_N,ResIII GHFFDFOM_02008 220668.lp_0939 3.54e-21 91.7 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli,3F4HM@33958|Lactobacillaceae 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase GHFFDFOM_02009 220668.lp_0939 0.0 939.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli,3F4HM@33958|Lactobacillaceae 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase GHFFDFOM_02010 1286171.EAL2_808p01380 1.16e-74 244.0 COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes,24DRR@186801|Clostridia 186801|Clostridia V Type I restriction - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S GHFFDFOM_02011 220668.lp_0941 1.27e-219 605.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HA65@91061|Bacilli,3F3NJ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase GHFFDFOM_02012 1121936.AUHI01000009_gene199 1.15e-51 176.0 COG0732@1|root,COG0732@2|Bacteria,1TPHR@1239|Firmicutes,4HFEJ@91061|Bacilli 91061|Bacilli V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S GHFFDFOM_02013 1692.BMAGN_1144 2.2e-51 175.0 COG0732@1|root,COG0732@2|Bacteria,2HZYJ@201174|Actinobacteria,4D29Q@85004|Bifidobacteriales 201174|Actinobacteria V Type I restriction modification DNA specificity domain - - - - - - - - - - - - Methylase_S GHFFDFOM_02014 220668.lp_0945 8.38e-120 342.0 COG0406@1|root,COG0406@2|Bacteria,1VCU1@1239|Firmicutes,4HQY2@91061|Bacilli,3F76I@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family XK27_09665 - - ko:K15640 - - - - ko00000 - - - His_Phos_1 GHFFDFOM_02015 220668.lp_0946 0.0 2000.0 COG4886@1|root,COG4932@1|root,COG4886@2|Bacteria,COG4932@2|Bacteria,1UWF2@1239|Firmicutes,4HGU0@91061|Bacilli,3F6D1@33958|Lactobacillaceae 91061|Bacilli M MucBP domain - - - - - - - - - - - - DUF285,Gram_pos_anchor,LRR_4,MucBP GHFFDFOM_02016 543734.LCABL_25980 1.42e-08 51.2 2DG6I@1|root,2ZUQQ@2|Bacteria,1W51C@1239|Firmicutes,4IGU7@91061|Bacilli,3F8SJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02017 220668.lp_0948 7.05e-113 324.0 COG0645@1|root,COG0645@2|Bacteria,1UIME@1239|Firmicutes,4ISNB@91061|Bacilli,3F6E7@33958|Lactobacillaceae 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_33 GHFFDFOM_02018 220668.lp_0949 6.58e-174 485.0 COG1396@1|root,COG1396@2|Bacteria,1V873@1239|Firmicutes,4HQNH@91061|Bacilli,3F762@33958|Lactobacillaceae 91061|Bacilli K sequence-specific DNA binding - - - - - - - - - - - - HTH_3 GHFFDFOM_02019 220668.lp_0950 3.8e-124 354.0 COG1476@1|root,COG1476@2|Bacteria,1UIXC@1239|Firmicutes 1239|Firmicutes K Helix-turn-helix domain - - - - - - - - - - - - FliG_C,HTH_3 GHFFDFOM_02020 220668.lp_0951 6.34e-55 179.0 COG0583@1|root,COG0583@2|Bacteria,1TTAM@1239|Firmicutes,4HFT5@91061|Bacilli,3FC6M@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_02021 220668.lp_0951 4.84e-121 351.0 COG0583@1|root,COG0583@2|Bacteria,1TTAM@1239|Firmicutes,4HFT5@91061|Bacilli,3FC6M@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_02022 220668.lp_0952 0.0 1231.0 COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1UZHI@1239|Firmicutes,4I3MZ@91061|Bacilli,3F4A4@33958|Lactobacillaceae 91061|Bacilli C FMN_bind - - - - - - - - - - - - FAD_binding_2,FMN_bind,FMN_red GHFFDFOM_02024 220668.lp_0954 4.3e-106 306.0 COG1846@1|root,COG1846@2|Bacteria,1V4SH@1239|Firmicutes,4HICC@91061|Bacilli,3FC7I@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_27,MarR GHFFDFOM_02025 220668.lp_0955 7.81e-148 416.0 COG1182@1|root,COG1182@2|Bacteria,1UGCK@1239|Firmicutes,4HAPQ@91061|Bacilli,3FBBW@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 GHFFDFOM_02026 220668.lp_0956 0.0 878.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,3F4EK@33958|Lactobacillaceae 91061|Bacilli J Asparaginyl-tRNA synthetase asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon GHFFDFOM_02027 60520.HR47_09275 3.39e-255 698.0 COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,4HAEC@91061|Bacilli,3F40A@33958|Lactobacillaceae 91061|Bacilli F aspartate--ammonia ligase asnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 - R00483 RC00010 ko00000,ko00001,ko01000 - - - AsnA GHFFDFOM_02028 220668.lp_0959 0.0 959.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepDA - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 GHFFDFOM_02029 220668.lp_0960 5.38e-290 792.0 COG0847@1|root,COG0847@2|Bacteria,1U55Z@1239|Firmicutes,4IEXD@91061|Bacilli,3F4VS@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - - GHFFDFOM_02030 220668.lp_0960a 9.05e-55 171.0 29PA4@1|root,30A89@2|Bacteria,1U6BK@1239|Firmicutes,4IG38@91061|Bacilli,3F7IZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02031 220668.lp_0961 4.95e-44 142.0 COG3415@1|root,COG3415@2|Bacteria,1U6HT@1239|Firmicutes,4IGA4@91061|Bacilli,3F7Y2@33958|Lactobacillaceae 91061|Bacilli L leucine-zipper of insertion element IS481 - - - - - - - - - - - - HTH_28 GHFFDFOM_02032 220668.lp_0962 0.0 1176.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,3F4PY@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind GHFFDFOM_02033 220668.lp_0963 4.05e-210 580.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,3F46Z@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD2 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 GHFFDFOM_02034 220668.lp_0965 5.06e-68 206.0 COG0640@1|root,COG0640@2|Bacteria,1U625@1239|Firmicutes,4IFR5@91061|Bacilli,3F6UW@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5 GHFFDFOM_02035 220668.lp_0966 8.34e-179 498.0 COG0431@1|root,COG0431@2|Bacteria,1VBJA@1239|Firmicutes,4HSVK@91061|Bacilli,3F41J@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red GHFFDFOM_02036 220668.lp_0967 3.91e-244 670.0 29NS0@1|root,309Q0@2|Bacteria,1U5GW@1239|Firmicutes,4IF7N@91061|Bacilli,3F5X3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02037 220668.lp_0968 3.28e-278 763.0 COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,4HCP3@91061|Bacilli,3F3M9@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibE - - - - - - - - - - - YibE_F GHFFDFOM_02038 220668.lp_0969 8.44e-163 457.0 COG5438@1|root,COG5438@2|Bacteria,1TSWX@1239|Firmicutes,4HBKX@91061|Bacilli,3F3S6@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibF - - - - - - - - - - - YibE_F GHFFDFOM_02039 220668.lp_0970 3.5e-132 375.0 COG0454@1|root,COG0456@2|Bacteria,1UFIT@1239|Firmicutes,4IESW@91061|Bacilli,3F3Y5@33958|Lactobacillaceae 91061|Bacilli K FR47-like protein - - - - - - - - - - - - Acetyltransf_1 GHFFDFOM_02040 220668.lp_0971 1.5e-156 439.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F4IS@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family gpm5 - - - - - - - - - - - His_Phos_1 GHFFDFOM_02041 220668.lp_0972 3.33e-64 196.0 2DKNE@1|root,30A1I@2|Bacteria,1U62P@1239|Firmicutes,4IFRU@91061|Bacilli,3F6W0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - EntA_Immun GHFFDFOM_02042 220668.lp_0973 3.48e-245 673.0 COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,4HGC2@91061|Bacilli,3F5CV@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 GHFFDFOM_02043 220668.lp_0975 0.0 883.0 COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HBAI@91061|Bacilli,3F3Z2@33958|Lactobacillaceae 91061|Bacilli G symporter xylP2 - - - - - - - - - - - MFS_2 GHFFDFOM_02044 220668.lp_0977 0.0 969.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,3F3UE@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M GHFFDFOM_02045 220668.lp_0979 1.2e-281 770.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli,3F4V2@33958|Lactobacillaceae 91061|Bacilli E Amino acid kinase family dapG GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT_7 GHFFDFOM_02046 220668.lp_0980 0.0 1302.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,3F3NT@33958|Lactobacillaceae 91061|Bacilli E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 GHFFDFOM_02047 220668.lp_0981 2.41e-66 202.0 COG4392@1|root,COG4392@2|Bacteria,1VH9Q@1239|Firmicutes,4HNDZ@91061|Bacilli,3F7IU@33958|Lactobacillaceae 91061|Bacilli S Branched-chain amino acid transport protein (AzlD) azlD - - - - - - - - - - - AzlD GHFFDFOM_02048 220668.lp_0982 1.43e-155 437.0 COG1296@1|root,COG1296@2|Bacteria,1U49T@1239|Firmicutes,4HDIJ@91061|Bacilli,3F45S@33958|Lactobacillaceae 91061|Bacilli E branched-chain amino acid azlC - - - - - - - - - - - AzlC GHFFDFOM_02049 220668.lp_0984 1.75e-47 151.0 COG0789@1|root,COG0789@2|Bacteria,1U69E@1239|Firmicutes,4IG0J@91061|Bacilli,3F7CS@33958|Lactobacillaceae 91061|Bacilli K MerR HTH family regulatory protein - - - - - - - - - - - - MerR_1 GHFFDFOM_02050 220668.lp_0412 3.08e-111 324.0 COG1266@1|root,COG1266@2|Bacteria,1U5JH@1239|Firmicutes,4IFAB@91061|Bacilli,3F637@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity plnP - - - - - - - - - - - Abi GHFFDFOM_02051 220668.lp_0411 5.58e-291 794.0 COG0463@1|root,COG0463@2|Bacteria,1UV29@1239|Firmicutes,4I29G@91061|Bacilli,3F8S5@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 GHFFDFOM_02053 220668.lp_0409 4.08e-39 130.0 2DKT4@1|root,30AQB@2|Bacteria,1U6ZA@1239|Firmicutes,4IGTJ@91061|Bacilli,3F8RH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02054 220668.lp_0406 8.53e-34 115.0 29QFH@1|root,30BEW@2|Bacteria,1U80K@1239|Firmicutes,4IHXZ@91061|Bacilli,3FADY@33958|Lactobacillaceae 91061|Bacilli - - plnJ - - - - - - - - - - - - GHFFDFOM_02055 220668.lp_0405 3.29e-32 112.0 29QE9@1|root,30BDK@2|Bacteria,1U7YQ@1239|Firmicutes,4IHW4@91061|Bacilli,3FABZ@33958|Lactobacillaceae 91061|Bacilli - - plnK - - - - - - - - - - - - GHFFDFOM_02056 220668.lp_0404 9.76e-153 429.0 2CBER@1|root,30AMI@2|Bacteria,1U6V7@1239|Firmicutes,4IGP3@91061|Bacilli,3F8J9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02057 220668.lp_0403 6.24e-25 93.2 2BSTZ@1|root,32MXF@2|Bacteria,1U8C2@1239|Firmicutes,4IIA1@91061|Bacilli,3FATJ@33958|Lactobacillaceae 91061|Bacilli - - plnR - - - - - - - - - - - - GHFFDFOM_02058 220668.lp_0402 1.15e-43 141.0 29PWX@1|root,30AV8@2|Bacteria,1U75A@1239|Firmicutes,4IGZZ@91061|Bacilli,3F8ZZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02060 220668.lp_0400 8.8e-265 727.0 COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,3F3QK@33958|Lactobacillaceae 91061|Bacilli P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family napA - - - - - - - - - - - Na_H_Exchanger GHFFDFOM_02061 220668.lp_0399 0.0 888.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans GHFFDFOM_02062 220668.lp_0397 8.38e-192 532.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,3F55S@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - - - - - - - - - - - Hydrolase_3 GHFFDFOM_02063 220668.lp_0396 2.35e-212 586.0 COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TVGS@1239|Firmicutes,4I2JI@91061|Bacilli,3F5KS@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - AraC_binding,HTH_18 GHFFDFOM_02064 220668.lp_0395 4.15e-188 522.0 COG0561@1|root,COG0561@2|Bacteria,1UYU8@1239|Firmicutes,4HE0K@91061|Bacilli,3F3ZW@33958|Lactobacillaceae 91061|Bacilli G Sucrose-6F-phosphate phosphohydrolase - - 3.1.3.102,3.1.3.104,3.1.3.23 ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R00804,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 GHFFDFOM_02065 220668.lp_0394 4.32e-260 714.0 COG0477@1|root,COG2814@2|Bacteria,1TQZ7@1239|Firmicutes,4HERG@91061|Bacilli,3F54C@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein - - - - - - - - - - - - MFS_1 GHFFDFOM_02066 60520.HR47_09040 1.31e-153 430.0 COG0110@1|root,COG0110@2|Bacteria,1TQQB@1239|Firmicutes,4HG1G@91061|Bacilli,3FC9A@33958|Lactobacillaceae 91061|Bacilli S Maltose acetyltransferase lacA - 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac GHFFDFOM_02068 220668.lp_3549 3.02e-71 219.0 COG1349@1|root,COG1349@2|Bacteria,1UXYW@1239|Firmicutes,4IQMP@91061|Bacilli,3F68Z@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - ko:K02444 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR GHFFDFOM_02069 220668.lp_3551 0.0 1648.0 COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,4HC2J@91061|Bacilli,3F3TZ@33958|Lactobacillaceae 91061|Bacilli G Phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N GHFFDFOM_02070 60520.HR47_10905 1.73e-93 272.0 COG5506@1|root,COG5506@2|Bacteria,1U7K6@1239|Firmicutes,4IHH7@91061|Bacilli,3F9UU@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1694) - - - - - - - - - - - - DUF1694 GHFFDFOM_02071 220668.lp_3553 6.83e-133 376.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,3F5U8@33958|Lactobacillaceae 91061|Bacilli S Maltose O-acetyltransferase maa - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - CM_2,Hexapep,Hexapep_2,Mac GHFFDFOM_02072 220668.lp_3554 0.0 962.0 COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,4HAWS@91061|Bacilli,3F4PN@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the conversion of L-arabinose to L-ribulose araA - 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 - R01761 RC00516 ko00000,ko00001,ko01000 - - - Arabinose_Iso_C,Arabinose_Isome GHFFDFOM_02073 220668.lp_3555 1.06e-175 489.0 COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,4H9W0@91061|Bacilli,3F43P@33958|Lactobacillaceae 91061|Bacilli G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source araD GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II GHFFDFOM_02074 220668.lp_3556 0.0 1056.0 COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,4HBGF@91061|Bacilli,3F4HI@33958|Lactobacillaceae 91061|Bacilli G carbohydrate kinase FGGY araB - 2.7.1.16 ko:K00853 ko00040,ko01100,map00040,map01100 - R01526,R02439 RC00002,RC00538 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N GHFFDFOM_02075 220668.lp_3557 0.0 892.0 COG0477@1|root,COG0477@2|Bacteria,1UHPS@1239|Firmicutes,4IS5K@91061|Bacilli,3FBSI@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family araP - - - - - - - - - - - Sugar_tr GHFFDFOM_02076 220668.lp_3558 3.44e-262 717.0 COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,4HARD@91061|Bacilli,3F3ZM@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator araR - - ko:K02103 - - - - ko00000,ko03000 - - - GntR,Peripla_BP_3 GHFFDFOM_02077 220668.lp_3571 1.82e-160 449.0 COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,4HBPF@91061|Bacilli,3F529@33958|Lactobacillaceae 91061|Bacilli G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) nanE - 5.1.3.9 ko:K01788 ko00520,map00520 - R02087 RC00290 ko00000,ko00001,ko01000 - - - NanE GHFFDFOM_02078 220668.lp_3572 2.18e-289 790.0 COG0446@1|root,COG0446@2|Bacteria,1TRNN@1239|Firmicutes,4HE8X@91061|Bacilli,3F60G@33958|Lactobacillaceae 91061|Bacilli S Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,Reductase_C GHFFDFOM_02079 220668.lp_3573 2.43e-91 266.0 2AK1X@1|root,31ARI@2|Bacteria,1V717@1239|Firmicutes,4HIQ9@91061|Bacilli,3F6WW@33958|Lactobacillaceae 91061|Bacilli S Pyrimidine dimer DNA glycosylase - - - - - - - - - - - - Pyr_excise GHFFDFOM_02080 1074451.CRL705_640 5.35e-65 204.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve GHFFDFOM_02081 526222.Desal_2733 6.88e-05 52.8 2AJB7@1|root,319WD@2|Bacteria,1R527@1224|Proteobacteria,43BE6@68525|delta/epsilon subdivisions,2X6SN@28221|Deltaproteobacteria,2MH6B@213115|Desulfovibrionales 28221|Deltaproteobacteria S FRG - - - - - - - - - - - - FRG GHFFDFOM_02082 1291743.LOSG293_090050 2.56e-124 358.0 COG1396@1|root,COG5294@1|root,COG1396@2|Bacteria,COG5294@2|Bacteria,1W1Q8@1239|Firmicutes,4I0U9@91061|Bacilli,3F7V4@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 GHFFDFOM_02083 1291743.LOSG293_090040 1.32e-224 619.0 COG0793@1|root,COG0793@2|Bacteria,1U9Z0@1239|Firmicutes,4HRFD@91061|Bacilli 91061|Bacilli M Peptidase family S41 - - - - - - - - - - - - Peptidase_S41 GHFFDFOM_02084 1400520.LFAB_17300 3.8e-25 94.7 29PHS@1|root,30AFX@2|Bacteria,1U6KZ@1239|Firmicutes,4IGDS@91061|Bacilli,3F84Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02085 1140001.I571_03037 2.33e-100 302.0 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 GHFFDFOM_02086 1423816.BACQ01000033_gene1383 1.53e-26 100.0 2AII8@1|root,31906@2|Bacteria,1U82Q@1239|Firmicutes,4II04@91061|Bacilli,3FAGG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02087 1140001.I571_03039 0.0 2388.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes 1239|Firmicutes O Belongs to the peptidase S8 family prtP - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - Big_3_2,Inhibitor_I9,PA,Peptidase_S8,SLAP,SLH,fn3_5 GHFFDFOM_02089 1122149.BACN01000113_gene2019 1.04e-98 296.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 GHFFDFOM_02090 1033837.WANG_1127 6.46e-221 616.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HC0Q@91061|Bacilli,3F4RB@33958|Lactobacillaceae 91061|Bacilli L PFAM Transposase, IS204 IS1001 IS1096 IS1165 tnp2 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 GHFFDFOM_02091 1423816.BACQ01000041_gene1636 2.63e-44 143.0 29P8A@1|root,30A6D@2|Bacteria,1U69B@1239|Firmicutes,4IG0G@91061|Bacilli,3F7CJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02092 220668.45723572 0.0 1342.0 COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,3F4W6@33958|Lactobacillaceae 91061|Bacilli L This gene contains a nucleotide ambiguity which may be the result of a sequencing error traI - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim,Toprim_Crpt,zf-C4_Topoisom GHFFDFOM_02093 1114972.AUAW01000027_gene719 0.0 1286.0 COG0507@1|root,COG0507@2|Bacteria,1VQWC@1239|Firmicutes,4HD6B@91061|Bacilli,3F4DP@33958|Lactobacillaceae 91061|Bacilli L MobA MobL family protein traA - - - - - - - - - - - MobA_MobL GHFFDFOM_02094 1138822.PL11_10675 7.49e-32 112.0 29P8B@1|root,30A6E@2|Bacteria,1U69C@1239|Firmicutes,4IG0H@91061|Bacilli,3F7CM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02095 1033837.WANG_1719 1.21e-54 171.0 2EJES@1|root,33D5R@2|Bacteria,1VKZC@1239|Firmicutes,4HRGI@91061|Bacilli,3F6Y2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02096 1231336.L248_2358 1.41e-93 282.0 COG0500@1|root,COG2226@2|Bacteria,1TSAZ@1239|Firmicutes,4HIIG@91061|Bacilli,3F4S0@33958|Lactobacillaceae 91061|Bacilli Q Methyltransferase - - - - - - - - - - - - Methyltransf_11 GHFFDFOM_02097 1291743.LOSG293_220360 6.45e-230 637.0 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,3F55E@33958|Lactobacillaceae 91061|Bacilli S Replication initiator protein A repA - - - - - - - - - - - RepA_N GHFFDFOM_02098 1291743.LOSG293_220350 3.57e-47 151.0 29P7R@1|root,30A5U@2|Bacteria,1U68J@1239|Firmicutes,4IFZF@91061|Bacilli,3F7B0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02099 1291743.LOSG293_220340 6.93e-194 537.0 COG1192@1|root,COG1192@2|Bacteria,1V6Q6@1239|Firmicutes,4HINH@91061|Bacilli,3F477@33958|Lactobacillaceae 91061|Bacilli D CobQ CobB MinD ParA nucleotide binding domain protein - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 GHFFDFOM_02100 1423816.BACQ01000031_gene1363 2.93e-11 68.6 29PQT@1|root,30AKJ@2|Bacteria,1U6TR@1239|Firmicutes,4IGMJ@91061|Bacilli,3F8H1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02101 1122149.BACN01000102_gene1992 1.88e-43 142.0 29PR9@1|root,30APH@2|Bacteria,1U6Y6@1239|Firmicutes,4IGSC@91061|Bacilli,3F8PW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02102 908339.HMPREF9265_0219 4.76e-106 308.0 COG1309@1|root,COG1309@2|Bacteria,1V9ST@1239|Firmicutes,4HP6S@91061|Bacilli,3F5J7@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GHFFDFOM_02104 326425.lhe_0269 2.79e-304 831.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HBZF@91061|Bacilli,3FC6T@33958|Lactobacillaceae 91061|Bacilli C Pyridine nucleotide-disulfide oxidoreductase - - 1.8.1.7 ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim GHFFDFOM_02105 525309.HMPREF0494_0066 0.0 1341.0 COG4932@1|root,COG4932@2|Bacteria,1V001@1239|Firmicutes,4HBP0@91061|Bacilli,3FC22@33958|Lactobacillaceae 91061|Bacilli M Collagen binding domain - - - - - - - - - - - - Cna_B,Collagen_bind GHFFDFOM_02106 641146.HMPREF9020_01129 6.82e-66 200.0 COG0640@1|root,COG0640@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - HTH_20,HTH_5 GHFFDFOM_02107 908339.HMPREF9265_2038 9.68e-83 244.0 2BVFJ@1|root,33DER@2|Bacteria,1UNAF@1239|Firmicutes,4IU9D@91061|Bacilli,3F8J3@33958|Lactobacillaceae 91061|Bacilli S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 GHFFDFOM_02108 908339.HMPREF9265_2037 4.92e-130 370.0 COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,4HCFF@91061|Bacilli,3F429@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed pinR1 - - - - - - - - - - - HTH_7,Resolvase GHFFDFOM_02109 1193128.A200_00280 1.3e-13 68.6 293K5@1|root,2ZR24@2|Bacteria,2H0VY@201174|Actinobacteria,4D1PD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GHFFDFOM_02110 908339.HMPREF9265_0213 1.02e-138 393.0 2B85J@1|root,33TQQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GHFFDFOM_02111 525309.HMPREF0494_1089 1.68e-52 166.0 2FFI7@1|root,31U03@2|Bacteria,1U70K@1239|Firmicutes,4IGUX@91061|Bacilli,3F8TG@33958|Lactobacillaceae 91061|Bacilli S Bacterial toxin of type II toxin-antitoxin system, YafQ - - - ko:K19157 - - - - ko00000,ko01000,ko02048 - - - YafQ_toxin GHFFDFOM_02112 525309.HMPREF0494_1088 5.54e-39 132.0 COG3077@1|root,COG3077@2|Bacteria,1VJC4@1239|Firmicutes,4I1CX@91061|Bacilli,3F879@33958|Lactobacillaceae 91061|Bacilli L RelB antitoxin - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB GHFFDFOM_02113 1114972.AUAW01000027_gene740 1.79e-172 483.0 COG1192@1|root,COG1192@2|Bacteria,1V6Q6@1239|Firmicutes,4HINH@91061|Bacilli,3F477@33958|Lactobacillaceae 91061|Bacilli D CobQ CobB MinD ParA nucleotide binding domain protein - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 GHFFDFOM_02115 525309.HMPREF0494_0007 1.27e-234 649.0 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,3F55E@33958|Lactobacillaceae 91061|Bacilli S Replication initiator protein A repA - - - - - - - - - - - RepA_N GHFFDFOM_02116 220668.lp_3351 1.11e-111 321.0 2AJ3X@1|root,319NA@2|Bacteria,1UIQW@1239|Firmicutes,4ISQT@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02117 220668.lp_3350 2.11e-82 243.0 2BQC3@1|root,32J76@2|Bacteria,1UQDP@1239|Firmicutes,4IFH8@91061|Bacilli,3F6GE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02118 220668.lp_3349 4.98e-275 751.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,3FCD0@33958|Lactobacillaceae 91061|Bacilli L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 GHFFDFOM_02119 220668.lp_3348 1.7e-70 212.0 298U1@1|root,2ZVY8@2|Bacteria,1W3JF@1239|Firmicutes,4I1SS@91061|Bacilli,3F7JE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02120 220668.lp_3346 8.16e-86 252.0 COG3189@1|root,COG3189@2|Bacteria,1VABH@1239|Firmicutes,4HKI2@91061|Bacilli,3F715@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function, DUF488 yeaO - - - - - - - - - - - DUF488 GHFFDFOM_02121 220668.lp_3345 9.97e-94 273.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F67K@33958|Lactobacillaceae 91061|Bacilli P ArsC family spxA - - ko:K16509 - - - - ko00000 - - - ArsC GHFFDFOM_02122 220668.lp_3344 4.31e-86 254.0 COG1846@1|root,COG1846@2|Bacteria,1VQ9C@1239|Firmicutes,4HSIB@91061|Bacilli,3F887@33958|Lactobacillaceae 91061|Bacilli K Winged helix DNA-binding domain - - - ko:K22296 - - - - ko00000,ko03000 - - - MarR_2 GHFFDFOM_02123 220668.lp_3343 1.36e-209 578.0 COG0702@1|root,COG0702@2|Bacteria,1UY7W@1239|Firmicutes,4HDIS@91061|Bacilli,3F4M7@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10,NmrA GHFFDFOM_02124 220668.lp_3342 1.65e-112 323.0 COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,4HH4Y@91061|Bacilli,3F6QT@33958|Lactobacillaceae 91061|Bacilli I Phosphatidylglycerophosphatase A pgpA - - - - - - - - - - - PgpA GHFFDFOM_02125 220668.lp_3341 2.48e-215 594.0 COG4814@1|root,COG4814@2|Bacteria,1V910@1239|Firmicutes,4HF90@91061|Bacilli,3F5GH@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 GHFFDFOM_02126 220668.lp_3339 0.0 866.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease cycA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease GHFFDFOM_02127 220668.lp_3338 0.0 881.0 COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,4HCYW@91061|Bacilli,3FB8Z@33958|Lactobacillaceae 91061|Bacilli C Na H antiporter NhaC nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - iSB619.SA_RS12035 Na_H_antiporter GHFFDFOM_02128 60520.HR47_01360 1.46e-35 124.0 COG1611@1|root,COG1611@2|Bacteria,1U857@1239|Firmicutes,4II2Q@91061|Bacilli,3FAJF@33958|Lactobacillaceae 91061|Bacilli S Belongs to the LOG family - - - - - - - - - - - - - GHFFDFOM_02129 326425.lhe_0633 9.84e-42 137.0 COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,4HRGW@91061|Bacilli 91061|Bacilli KT PspC domain protein pspC - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC GHFFDFOM_02130 405566.lhv_0574 1.01e-117 337.0 COG1388@1|root,COG1388@2|Bacteria,1V3Q9@1239|Firmicutes,4HH9X@91061|Bacilli,3F7G7@33958|Lactobacillaceae 91061|Bacilli M Protein of unknown function (DUF1541) ydhK - - - - - - - - - - - DUF1541 GHFFDFOM_02131 543734.LCABL_04000 3.09e-245 672.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HDM3@91061|Bacilli,3F3UG@33958|Lactobacillaceae 91061|Bacilli L PFAM Integrase, catalytic core - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve GHFFDFOM_02132 862514.HMPREF0623_1603 8.06e-279 762.0 2EQYH@1|root,33II5@2|Bacteria,1VMH1@1239|Firmicutes,4HUIK@91061|Bacilli,3F5E7@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos GHFFDFOM_02133 1423815.BACR01000038_gene1874 8.21e-68 223.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,3F3NT@33958|Lactobacillaceae 91061|Bacilli E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 GHFFDFOM_02134 387344.LVIS_1260 2.36e-54 172.0 COG0515@1|root,COG0515@2|Bacteria,1U6QH@1239|Firmicutes,4IGHS@91061|Bacilli,3F8B4@33958|Lactobacillaceae 91061|Bacilli KLT serine threonine protein kinase - - - - - - - - - - - - - GHFFDFOM_02135 1138822.PL11_10550 3.8e-46 152.0 2EIVY@1|root,33CM8@2|Bacteria,1VI8G@1239|Firmicutes,4HY2K@91061|Bacilli,3FBQ2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02136 1138822.PL11_10545 2.93e-48 156.0 28WF1@1|root,2ZIF8@2|Bacteria,1W2PF@1239|Firmicutes,4HZUK@91061|Bacilli,3F8BE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02137 1138822.PL11_10540 9.05e-296 809.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,3F3WN@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA polymerase type-Y family polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH GHFFDFOM_02138 1267003.KB911445_gene538 6.8e-35 121.0 29QRJ@1|root,30BRF@2|Bacteria,1U8II@1239|Firmicutes,4IIGI@91061|Bacilli,3FB0W@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02139 1133569.AHYZ01000020_gene620 8.04e-120 353.0 COG1192@1|root,COG1192@2|Bacteria,1V1YN@1239|Firmicutes,4IQV7@91061|Bacilli,3FBJB@33958|Lactobacillaceae 91061|Bacilli D Cellulose biosynthesis protein BcsQ - - - - - - - - - - - - AAA_31 GHFFDFOM_02140 714313.LSA_2p00010 6.25e-118 363.0 COG1959@1|root,COG1959@2|Bacteria,1UBUD@1239|Firmicutes,4HB0A@91061|Bacilli,3F57X@33958|Lactobacillaceae 91061|Bacilli K Primase C terminal 1 (PriCT-1) repE - - - - - - - - - - - PriCT_1,Rrf2 GHFFDFOM_02141 1423734.JCM14202_2804 3.46e-93 274.0 COG4185@1|root,COG4185@2|Bacteria,1V4U7@1239|Firmicutes,4HHGF@91061|Bacilli,3F5H8@33958|Lactobacillaceae 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Zeta_toxin GHFFDFOM_02142 1400520.LFAB_17270 3.47e-54 170.0 2EJES@1|root,33D5R@2|Bacteria,1VKZC@1239|Firmicutes,4HRGI@91061|Bacilli,3F6Y2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02143 1423734.JCM14202_2802 3.41e-37 125.0 29P8B@1|root,30A6E@2|Bacteria,1U69C@1239|Firmicutes,4IG0H@91061|Bacilli,3F7CM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02144 220668.45723588 3.61e-131 390.0 COG0507@1|root,COG0507@2|Bacteria,1VQWC@1239|Firmicutes,4HD6B@91061|Bacilli,3F4DP@33958|Lactobacillaceae 91061|Bacilli L MobA MobL family protein traA - - - - - - - - - - - MobA_MobL GHFFDFOM_02145 1423807.BACO01000083_gene2423 5.17e-270 752.0 COG0507@1|root,COG0507@2|Bacteria,1VQWC@1239|Firmicutes,4HD6B@91061|Bacilli,3F4DP@33958|Lactobacillaceae 91061|Bacilli L MobA MobL family protein traA - - - - - - - - - - - MobA_MobL GHFFDFOM_02146 908339.HMPREF9265_1404 3.92e-47 153.0 29PC9@1|root,30AAH@2|Bacteria,1U6EB@1239|Firmicutes,4IG63@91061|Bacilli,3F7QB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02147 220668.45723586 1.34e-132 377.0 29NNG@1|root,309KE@2|Bacteria,1U59R@1239|Firmicutes,4IF1A@91061|Bacilli,3F5AZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02148 1291743.LOSG293_220130 2.57e-67 204.0 2BZG5@1|root,309WK@2|Bacteria,1U5UW@1239|Firmicutes,4IFIG@91061|Bacilli,3F6IN@33958|Lactobacillaceae 91061|Bacilli S Cag pathogenicity island, type IV secretory system - - - - - - - - - - - - T4SS_CagC GHFFDFOM_02149 1291743.LOSG293_220140 9.31e-72 216.0 2F48Y@1|root,33WZQ@2|Bacteria,1VVYR@1239|Firmicutes,4HW55@91061|Bacilli,3F6NH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02150 1291743.LOSG293_220150 3.84e-153 430.0 2ECAZ@1|root,3369B@2|Bacteria,1VEP6@1239|Firmicutes,4HQSU@91061|Bacilli,3F5SZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02151 908339.HMPREF9265_1761 0.0 1287.0 COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,4IQVJ@91061|Bacilli,3FBJF@33958|Lactobacillaceae 91061|Bacilli U AAA-like domain - - - - - - - - - - - - DUF87 GHFFDFOM_02152 1045004.OKIT_0529 0.0 878.0 COG4499@1|root,COG4499@2|Bacteria,1V1PS@1239|Firmicutes,4HGKF@91061|Bacilli 91061|Bacilli S WXG100 protein secretion system (Wss), protein YukC - - - - - - - - - - - - YukC GHFFDFOM_02153 1045004.OKIT_0530 2.78e-272 745.0 COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1VW67@1239|Firmicutes,4HWSY@91061|Bacilli 91061|Bacilli M CHAP domain - - - - - - - - - - - - Amidase_5,Beta-lactamase2,CHAP,NLPC_P60 GHFFDFOM_02154 1114972.AUAW01000027_gene719 0.0 1290.0 COG0507@1|root,COG0507@2|Bacteria,1VQWC@1239|Firmicutes,4HD6B@91061|Bacilli,3F4DP@33958|Lactobacillaceae 91061|Bacilli L MobA MobL family protein traA - - - - - - - - - - - MobA_MobL GHFFDFOM_02155 797515.HMPREF9103_01297 9.69e-66 200.0 29PC9@1|root,30AAH@2|Bacteria,1U6EB@1239|Firmicutes,4IG63@91061|Bacilli,3F7QB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02156 220668.45723586 1.9e-132 377.0 29NNG@1|root,309KE@2|Bacteria,1U59R@1239|Firmicutes,4IF1A@91061|Bacilli,3F5AZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02157 1045004.OKIT_0525 6.32e-66 201.0 2BZG5@1|root,3316I@2|Bacteria,1VHPT@1239|Firmicutes,4HPFA@91061|Bacilli 91061|Bacilli S Cag pathogenicity island, type IV secretory system - - - - - - - - - - - - T4SS_CagC GHFFDFOM_02158 908339.HMPREF9265_1763 3.64e-69 210.0 2F48Y@1|root,33WZQ@2|Bacteria,1VVYR@1239|Firmicutes,4HW55@91061|Bacilli,3F6NH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02159 908339.HMPREF9265_1762 3.29e-154 433.0 2ECAZ@1|root,3369B@2|Bacteria,1VEP6@1239|Firmicutes,4HQSU@91061|Bacilli,3F5SZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02160 1045004.OKIT_0528 0.0 1301.0 COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,4IQVJ@91061|Bacilli 91061|Bacilli U Psort location Cytoplasmic, score traE - - - - - - - - - - - DUF87 GHFFDFOM_02161 1291743.LOSG293_220170 0.0 884.0 COG4499@1|root,COG4499@2|Bacteria,1V1PS@1239|Firmicutes,4HGKF@91061|Bacilli,3F450@33958|Lactobacillaceae 91061|Bacilli S WXG100 protein secretion system (Wss), protein YukC - - - - - - - - - - - - YukC GHFFDFOM_02162 1045004.OKIT_0530 3.15e-278 760.0 COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1VW67@1239|Firmicutes,4HWSY@91061|Bacilli 91061|Bacilli M CHAP domain - - - - - - - - - - - - Amidase_5,Beta-lactamase2,CHAP,NLPC_P60 GHFFDFOM_02163 1123359.AUIQ01000090_gene154 3.99e-123 352.0 COG1961@1|root,COG1961@2|Bacteria,1V51N@1239|Firmicutes,4HDX2@91061|Bacilli,4B0ZS@81852|Enterococcaceae 91061|Bacilli L Resolvase, N terminal domain - - - - - - - - - - - - HTH_7,Resolvase GHFFDFOM_02164 1400520.LFAB_13540 7.8e-75 226.0 COG0589@1|root,COG0589@2|Bacteria,1V8UY@1239|Firmicutes,4HK2J@91061|Bacilli,3F6N5@33958|Lactobacillaceae 91061|Bacilli T Belongs to the universal stress protein A family usp2 - - - - - - - - - - - Usp GHFFDFOM_02165 1400520.LFAB_13535 4.71e-315 866.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp GHFFDFOM_02166 1400520.LFAB_13530 3.35e-49 166.0 COG1321@1|root,COG1321@2|Bacteria,1U6ER@1239|Firmicutes,4IG6I@91061|Bacilli,3F7RA@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix diphteria tox regulatory element - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress GHFFDFOM_02169 1140001.I571_03032 1.15e-162 455.0 COG3316@1|root,COG3316@2|Bacteria,1UTIC@1239|Firmicutes,4HCF1@91061|Bacilli,4B0YQ@81852|Enterococcaceae 91061|Bacilli L DDE domain - - - ko:K07498 - - - - ko00000 - - - DDE_Tnp_IS240 GHFFDFOM_02172 1400520.LFAB_17595 4.87e-45 145.0 29PU7@1|root,30ASC@2|Bacteria,1U71N@1239|Firmicutes,4IGW4@91061|Bacilli,3F8V3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02173 1400520.LFAB_17600 8.69e-185 514.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,3FB46@33958|Lactobacillaceae 91061|Bacilli D AAA domain - - - - - - - - - - - - AAA_31 GHFFDFOM_02174 797515.HMPREF9103_02050 1.3e-27 101.0 2BFIJ@1|root,329CF@2|Bacteria,1UPZ5@1239|Firmicutes,4IVDI@91061|Bacilli,3F8GB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02175 1074451.CRL705_1630 6.38e-64 194.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve GHFFDFOM_02176 220668.lp_0275 1.21e-217 608.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp GHFFDFOM_02177 220668.lp_0274 5.2e-156 438.0 COG1309@1|root,COG1309@2|Bacteria,1V3R8@1239|Firmicutes,4I42T@91061|Bacilli,3F5TD@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GHFFDFOM_02178 220668.lp_0273 8.9e-96 279.0 COG1959@1|root,COG1959@2|Bacteria,1V6FK@1239|Firmicutes,4HKZD@91061|Bacilli,3F73Q@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator ywnA - - - - - - - - - - - Rrf2 GHFFDFOM_02179 220668.lp_0272 7.84e-92 268.0 2F603@1|root,33YIJ@2|Bacteria,1VX0V@1239|Firmicutes,4HXF9@91061|Bacilli,3F6YU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02180 220668.lp_0271 3.37e-129 367.0 COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,4HFZX@91061|Bacilli,3F5PD@33958|Lactobacillaceae 91061|Bacilli H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein GHFFDFOM_02181 1136177.KCA1_2628 1.3e-203 588.0 COG5617@1|root,COG5617@2|Bacteria,1V5JN@1239|Firmicutes,4HUFZ@91061|Bacilli 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - GHFFDFOM_02182 220668.lp_0269 0.0 1834.0 COG0438@1|root,COG1887@1|root,COG0438@2|Bacteria,COG1887@2|Bacteria,1TSEW@1239|Firmicutes,4HCKN@91061|Bacilli,3F8U6@33958|Lactobacillaceae 91061|Bacilli H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase tagF2 - 2.7.8.12 ko:K09809 - - - - ko00000,ko01000 - - - Glycos_transf_1,Glyphos_transf GHFFDFOM_02183 220668.lp_0268 4.5e-303 825.0 COG1887@1|root,COG1887@2|Bacteria,1TP75@1239|Firmicutes,4H9Q1@91061|Bacilli,3FC1J@33958|Lactobacillaceae 91061|Bacilli M glycerophosphotransferase tagB GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.8.12,2.7.8.45 ko:K09809,ko:K21591 - - R11612 - ko00000,ko01000 - - - Glyphos_transf GHFFDFOM_02184 220668.lp_0267 1.21e-94 275.0 COG0615@1|root,COG0615@2|Bacteria,1V3KY@1239|Firmicutes,4HGWZ@91061|Bacilli,3F65R@33958|Lactobacillaceae 91061|Bacilli IM Glycerol-3-phosphate cytidylyltransferase tagD - 2.7.7.15,2.7.7.39 ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 M00090 R00856,R01890,R02590 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like GHFFDFOM_02185 220668.lp_0266 2.6e-185 515.0 2F4SR@1|root,33XFD@2|Bacteria,1VW0F@1239|Firmicutes,4HWCG@91061|Bacilli,3F6TR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02186 220668.lp_0265 0.0 1190.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F5R5@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system, EIIB pts5ABC - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC GHFFDFOM_02187 220668.lp_0264 0.0 1266.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system pts4ABC - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC GHFFDFOM_02188 220668.lp_0263 0.0 1132.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein treC - 3.2.1.93 ko:K01226 ko00500,map00500 - R00837,R06113 RC00049 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C GHFFDFOM_02189 220668.lp_0262 1.68e-166 466.0 COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli,3F62J@33958|Lactobacillaceae 91061|Bacilli K UTRA treR - - ko:K03486 - - - - ko00000,ko03000 - - - GntR,UTRA GHFFDFOM_02190 220668.lp_0261 2.21e-56 176.0 2FGRX@1|root,348MC@2|Bacteria,1VYT7@1239|Firmicutes,4HY30@91061|Bacilli,3F8YI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02191 220668.lp_0260 7.55e-58 179.0 COG3877@1|root,COG3877@2|Bacteria,1VGSH@1239|Firmicutes,4HQ68@91061|Bacilli,3F84H@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2089) - - - - - - - - - - - - DUF2089 GHFFDFOM_02192 220668.lp_0259 1.27e-181 506.0 COG3201@1|root,COG3201@2|Bacteria,1VE5T@1239|Firmicutes,4HMNW@91061|Bacilli,3F3MB@33958|Lactobacillaceae 91061|Bacilli H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter GHFFDFOM_02193 220668.lp_0257 6.72e-203 560.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,3F3MK@33958|Lactobacillaceae 91061|Bacilli E Methionine Aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 GHFFDFOM_02194 220668.lp_0256 7.54e-211 583.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,3F4VD@33958|Lactobacillaceae 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family mccA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00609 R00897,R03601,R04859,R10305 RC00020,RC00069,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02385 PALP GHFFDFOM_02195 220668.lp_0255 5.78e-268 734.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,3F3Y2@33958|Lactobacillaceae 91061|Bacilli E cystathionine mccB GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27250 Cys_Met_Meta_PP GHFFDFOM_02196 220668.lp_0254 4.3e-124 353.0 COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli,3F63E@33958|Lactobacillaceae 91061|Bacilli E Bacterial transferase hexapeptide (six repeats) cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,SATase_N GHFFDFOM_02197 220668.lp_0253 1.17e-244 672.0 COG0524@1|root,COG0524@2|Bacteria,1TQER@1239|Firmicutes,4HEEF@91061|Bacilli,3FC1M@33958|Lactobacillaceae 91061|Bacilli G pfkB family carbohydrate kinase - - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB GHFFDFOM_02198 220668.lp_0252 1.22e-166 466.0 2DBAP@1|root,2Z844@2|Bacteria,1TQX7@1239|Firmicutes,4HABQ@91061|Bacilli,3F5QS@33958|Lactobacillaceae 91061|Bacilli S KDGP aldolase - - 4.1.2.14 ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 M00061,M00631 R05605 RC00307,RC00435 ko00000,ko00001,ko00002,ko01000 - - - KDGP_aldolase GHFFDFOM_02199 220668.lp_0251 2.06e-258 709.0 COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,4HC3U@91061|Bacilli,3F4MN@33958|Lactobacillaceae 91061|Bacilli H L-seryl-tRNA selenium transferase selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - SelA GHFFDFOM_02200 220668.lp_0250 1.73e-269 737.0 COG3964@1|root,COG3964@2|Bacteria,1TPXM@1239|Firmicutes,4HBNV@91061|Bacilli,3F4S7@33958|Lactobacillaceae 91061|Bacilli S Amidohydrolase family dho - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 GHFFDFOM_02201 220668.lp_0249 3.61e-267 731.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4H9V2@91061|Bacilli,3F4FK@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) - - - ko:K09963 - - - - ko00000 - - - DUF871 GHFFDFOM_02202 220668.lp_0248 6.14e-53 166.0 29PYN@1|root,30AX4@2|Bacteria,1U77X@1239|Firmicutes,4IH2Q@91061|Bacilli,3F937@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02203 220668.lp_0247 9.5e-295 808.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F54Z@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane pts3C - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC GHFFDFOM_02204 220668.lp_0245 3.26e-160 449.0 COG2188@1|root,COG2188@2|Bacteria,1V1UW@1239|Firmicutes,4IPXK@91061|Bacilli,3FBEG@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - GntR,UTRA GHFFDFOM_02205 220668.lp_0244 2.21e-127 362.0 COG0431@1|root,COG0431@2|Bacteria,1V2V7@1239|Firmicutes,4HFMV@91061|Bacilli,3FCC1@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - ko:K19784 - - - - ko00000 - - - FMN_red GHFFDFOM_02206 220668.lp_0243 0.0 884.0 COG4320@1|root,COG4320@2|Bacteria,1UCBA@1239|Firmicutes,4HBCI@91061|Bacilli,3F3JA@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2252) - - - ko:K13730 ko05100,map05100 - - - ko00000,ko00001 - - - DUF2252 GHFFDFOM_02207 220668.lp_0242 2.41e-106 306.0 COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,3F68C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the NDK family ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK GHFFDFOM_02208 220668.lp_0240 2.98e-90 264.0 2C2FZ@1|root,309XY@2|Bacteria,1U5WU@1239|Firmicutes,4IFKC@91061|Bacilli,3F6MP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02209 220668.lp_0239 1.22e-125 358.0 29P5Z@1|root,30A44@2|Bacteria,1U660@1239|Firmicutes,4IFW1@91061|Bacilli,3F75C@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02210 220668.lp_0237 7.19e-68 206.0 29PK3@1|root,30AI8@2|Bacteria,1U6QA@1239|Firmicutes,4IGHE@91061|Bacilli,3F8AK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02211 220668.lp_0236 1.96e-75 225.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F7I4@33958|Lactobacillaceae 91061|Bacilli O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin GHFFDFOM_02212 220668.lp_0235 1.21e-111 322.0 29NVD@1|root,309TG@2|Bacteria,1U5NP@1239|Firmicutes,4IFD9@91061|Bacilli,3F686@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02213 220668.lp_0233 2.61e-282 771.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,3F448@33958|Lactobacillaceae 91061|Bacilli C mannitol-1-phosphate 5-dehydrogenase activity mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C GHFFDFOM_02214 220668.lp_0232 5.33e-103 298.0 COG4668@1|root,COG4668@2|Bacteria,1V77P@1239|Firmicutes,4HIM2@91061|Bacilli,3F6EP@33958|Lactobacillaceae 91061|Bacilli G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane mtlF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02798 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2 GHFFDFOM_02215 220668.lp_0231 0.0 1330.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HABH@91061|Bacilli,3F561@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain mtlR - - ko:K03483 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB GHFFDFOM_02216 220668.lp_0230 0.0 1150.0 COG2213@1|root,COG2213@2|Bacteria,1TPE3@1239|Firmicutes,4HAVV@91061|Bacilli,3F52S@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit mtlA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIC,PTS_IIB GHFFDFOM_02217 220668.lp_0228 0.0 962.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD1 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 GHFFDFOM_02219 220668.lp_0226 3.16e-170 475.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,3F3NR@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso GHFFDFOM_02220 220668.lp_0224 1.2e-91 268.0 29P27@1|root,30A0D@2|Bacteria,1U60Z@1239|Firmicutes,4IFPT@91061|Bacilli,3F6T6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02221 220668.lp_0223 1.28e-102 297.0 COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,4HW8H@91061|Bacilli,3F6ZK@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N GHFFDFOM_02222 220668.lp_0221 5.3e-202 558.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HACK@91061|Bacilli,3F4XF@33958|Lactobacillaceae 91061|Bacilli S reductase dkgB - - - - - - - - - - - Aldo_ket_red GHFFDFOM_02223 220668.lp_0220 6.07e-117 334.0 COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli,3F6A9@33958|Lactobacillaceae 91061|Bacilli O Belongs to the glutathione peroxidase family gpo - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx GHFFDFOM_02224 220668.lp_0219 1.43e-131 373.0 COG4721@1|root,COG4721@2|Bacteria,1V5J6@1239|Firmicutes,4HGBR@91061|Bacilli,3FBNX@33958|Lactobacillaceae 91061|Bacilli S ABC transporter permease - - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt GHFFDFOM_02225 220668.lp_0218 0.0 898.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,3FBS0@33958|Lactobacillaceae 91061|Bacilli P ABC transporter - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran GHFFDFOM_02226 220668.lp_0217 2.13e-150 423.0 COG0619@1|root,COG0619@2|Bacteria,1TUDZ@1239|Firmicutes,4HCPC@91061|Bacilli,3F4FG@33958|Lactobacillaceae 91061|Bacilli P cobalt transport ykoC - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ GHFFDFOM_02227 220668.lp_0215 0.0 943.0 COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,4H9VW@91061|Bacilli,3F4UR@33958|Lactobacillaceae 91061|Bacilli S ATPases associated with a variety of cellular activities - - - ko:K18231,ko:K19349 ko02010,map02010 - - - br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121.1,3.A.1.121.2,3.A.1.121.3 - - ABC_tran,ABC_tran_Xtn GHFFDFOM_02228 220668.lp_0214 5.66e-74 223.0 COG0239@1|root,COG0239@2|Bacteria 2|Bacteria D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB GHFFDFOM_02229 220668.lp_0213 3.18e-77 230.0 COG0239@1|root,COG0239@2|Bacteria,1VM30@1239|Firmicutes,4HRC4@91061|Bacilli,3F8A8@33958|Lactobacillaceae 91061|Bacilli U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB GHFFDFOM_02230 1136177.KCA1_0189 3.81e-18 77.0 29PVU@1|root,30AU4@2|Bacteria,1U73Y@1239|Firmicutes,4IGYE@91061|Bacilli,3F8XV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02231 220668.lp_0210 1.5e-277 759.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase GHFFDFOM_02232 220668.lp_0209 1.53e-208 576.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,3F4QZ@33958|Lactobacillaceae 91061|Bacilli K Domain of unknown function (DUF814) fbpA - - - - - - - - - - - DUF814,FbpA GHFFDFOM_02233 220668.lp_0208 4.69e-79 234.0 COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,4HINV@91061|Bacilli,3F88X@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 GHFFDFOM_02234 220668.lp_0207 6.33e-46 147.0 29P8V@1|root,30A6Z@2|Bacteria,1U69W@1239|Firmicutes,4IG13@91061|Bacilli,3F7EF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02235 60520.HR47_03225 4.12e-228 629.0 COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,4HAZ2@91061|Bacilli,3F414@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase family protein yghZ - - ko:K19265 - - - - ko00000,ko01000 - - - Aldo_ket_red GHFFDFOM_02236 220668.lp_0205 6.7e-148 416.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F5SD@33958|Lactobacillaceae 91061|Bacilli G phosphoglycerate mutase pgm1 - - - - - - - - - - - His_Phos_1 GHFFDFOM_02237 220668.lp_0204 1.24e-259 711.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,3F4IU@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 GHFFDFOM_02238 220668.lp_0203 1.45e-278 762.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,3F4JJ@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT_4 GHFFDFOM_02239 220668.lp_0202 2.65e-102 296.0 COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,4HIRW@91061|Bacilli,3F7FI@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain yiaC - - ko:K03826 - - - - ko00000,ko01000 - - - Acetyltransf_10,Acetyltransf_7 GHFFDFOM_02240 220668.lp_0201 0.0 1066.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GHFFDFOM_02241 220668.lp_0200 0.0 1087.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GHFFDFOM_02242 220668.lp_0199 1.03e-201 558.0 COG1396@1|root,COG1396@2|Bacteria,1VDMN@1239|Firmicutes,4HDVP@91061|Bacilli,3F5A3@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix - - - ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3,TPR_12,TPR_2 GHFFDFOM_02244 220668.lp_0197 0.0 1383.0 COG3827@1|root,COG4932@1|root,COG3827@2|Bacteria,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,3F4FM@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - Cna_B,Collagen_bind,SdrD_B GHFFDFOM_02245 220668.lp_0194 4.92e-212 586.0 COG0583@1|root,COG0583@2|Bacteria,1V5VW@1239|Firmicutes,4HHDY@91061|Bacilli,3F5F3@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_02246 220668.lp_0193 0.0 1174.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein malL - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,DUF3459,Malt_amylase_C GHFFDFOM_02247 220668.lp_0192 0.0 874.0 COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,4HA18@91061|Bacilli,3F3VX@33958|Lactobacillaceae 91061|Bacilli C Na H antiporter NhaC nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter GHFFDFOM_02248 220668.lp_0190 9.92e-212 585.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,3F3WU@33958|Lactobacillaceae 91061|Bacilli C nadph quinone reductase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 GHFFDFOM_02249 220668.lp_0189 0.0 1180.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein - - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,DUF3459,Malt_amylase_C GHFFDFOM_02250 220668.lp_0188 2.4e-230 634.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli,3F4JE@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LacI family scrR - - ko:K02529,ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 GHFFDFOM_02251 220668.lp_0187 0.0 1047.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,3F4UD@33958|Lactobacillaceae 91061|Bacilli G invertase scrB - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N GHFFDFOM_02252 220668.lp_0185 0.0 1188.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system scrA - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC GHFFDFOM_02253 278197.PEPE_0517 0.0 1466.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,3F3RU@33958|Lactobacillaceae 91061|Bacilli G alpha-galactosidase melA - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase GHFFDFOM_02254 220668.lp_0184 1.54e-216 596.0 COG1940@1|root,COG1940@2|Bacteria,1TQU4@1239|Firmicutes,4HA1C@91061|Bacilli,3F3K8@33958|Lactobacillaceae 91061|Bacilli GK ROK family scrK - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK GHFFDFOM_02255 220668.lp_0183 8.23e-61 186.0 COG4095@1|root,COG4095@2|Bacteria,1VBI9@1239|Firmicutes,4HMY5@91061|Bacilli,3F7IR@33958|Lactobacillaceae 91061|Bacilli S Sugar efflux transporter for intercellular exchange ygbF - - - - - - - - - - - MtN3_slv GHFFDFOM_02256 220668.lp_0182 0.0 1878.0 COG3291@1|root,COG4724@1|root,COG3291@2|Bacteria,COG4724@2|Bacteria,1TPGB@1239|Firmicutes,4HDJJ@91061|Bacilli,3F77D@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolase family 85 - - 3.2.1.96 ko:K01227 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Big_3,F5_F8_type_C,FIVAR,G5,Glyco_hydro_85,Gram_pos_anchor,PKD,YSIRK_signal GHFFDFOM_02257 220668.lp_0181 0.0 1550.0 COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,3F3PG@33958|Lactobacillaceae 91061|Bacilli G hydrolase, family 65, central catalytic mapA - 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 - R01555 RC00049 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m GHFFDFOM_02258 220668.lp_0180 2.44e-267 731.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,3FC3D@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 GHFFDFOM_02259 220668.lp_0179 0.0 897.0 COG0366@1|root,COG0366@2|Bacteria,1U7JS@1239|Firmicutes,4HF0J@91061|Bacilli,3F5JM@33958|Lactobacillaceae 91061|Bacilli G Glycogen debranching enzyme, glucanotransferase domain malS - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase GHFFDFOM_02260 220668.lp_0178 1.75e-191 532.0 COG5521@1|root,COG5521@2|Bacteria,1V7S4@1239|Firmicutes,4HJ3V@91061|Bacilli,3F4T5@33958|Lactobacillaceae 91061|Bacilli S maltodextrose utilization protein MalA malA - - - - - - - - - - - DUF1189 GHFFDFOM_02261 220668.lp_0177 2.83e-206 571.0 COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,4HC5K@91061|Bacilli,3F4NP@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease malD GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0033037,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043211,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 GHFFDFOM_02262 220668.lp_0176 3.74e-302 825.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli,3F4J1@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component malC GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 GHFFDFOM_02263 220668.lp_0175 9.45e-299 815.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4HBHE@91061|Bacilli,3FC77@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein mdxE - - ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 M00207,M00491,M00599 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.38 - iYO844.BSU34610 SBP_bac_8 GHFFDFOM_02264 220668.lp_0174 0.0 1158.0 COG0366@1|root,COG0366@2|Bacteria,1UY2T@1239|Firmicutes,4HBRE@91061|Bacilli,3FC10@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain malA1 - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,Malt_amylase_C GHFFDFOM_02265 220668.lp_0173 1.83e-231 637.0 COG1609@1|root,COG1609@2|Bacteria,1U6Z4@1239|Firmicutes,4HC2A@91061|Bacilli,3F3ZC@33958|Lactobacillaceae 91061|Bacilli K helix_turn _helix lactose operon repressor yvdE - - - - - - - - - - - LacI,Peripla_BP_3 GHFFDFOM_02266 220668.lp_0172 2.65e-245 673.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli,3F4TM@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LacI family malR1 - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 GHFFDFOM_02267 220668.lp_0171 4e-172 479.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,3F4J6@33958|Lactobacillaceae 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP GHFFDFOM_02268 220668.lp_0170 6.76e-75 224.0 COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes,4HKCN@91061|Bacilli,3F6YE@33958|Lactobacillaceae 91061|Bacilli S PTS system fructose IIA component dhaM GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05881 ko00561,map00561 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000,ko02000 - - - EIIA-man GHFFDFOM_02269 220668.lp_0169 2.75e-131 373.0 COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,4HGZY@91061|Bacilli,3F5VS@33958|Lactobacillaceae 91061|Bacilli S Dak2 dhaL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak2 GHFFDFOM_02270 220668.lp_0168 3.88e-239 657.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,4H9VS@91061|Bacilli,3F4F2@33958|Lactobacillaceae 91061|Bacilli G Dak1 domain dhaK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05878 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak1 GHFFDFOM_02271 220668.lp_0166 2.35e-243 667.0 COG2376@1|root,COG2376@2|Bacteria,1UZIM@1239|Firmicutes,4HEWJ@91061|Bacilli,3F4HN@33958|Lactobacillaceae 91061|Bacilli G Dak1 domain dhaK2 - 2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01059 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Dak1 GHFFDFOM_02272 220668.lp_0165 1.85e-121 346.0 COG1309@1|root,COG1309@2|Bacteria,1V5RP@1239|Firmicutes,4HP5H@91061|Bacilli,3F6G7@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family XK27_02085 - - - - - - - - - - - TetR_C_8,TetR_N GHFFDFOM_02274 220668.lp_0164 2.04e-99 290.0 COG3275@1|root,COG3275@2|Bacteria,1TTD8@1239|Firmicutes,4IFBB@91061|Bacilli,3F650@33958|Lactobacillaceae 91061|Bacilli T ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt GHFFDFOM_02275 220668.lp_0163 0.0 957.0 COG1960@1|root,COG2025@1|root,COG1960@2|Bacteria,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,3F4ZT@33958|Lactobacillaceae 91061|Bacilli C Electron transfer flavoprotein FAD-binding domain etfA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 ko:K03522,ko:K22432 - - - - ko00000,ko01000,ko04147 - - - ETF,ETF_alpha GHFFDFOM_02276 220668.lp_0162 3.98e-151 425.0 COG1309@1|root,COG1309@2|Bacteria,1VG1F@1239|Firmicutes,4HPER@91061|Bacilli,3F6KD@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_N GHFFDFOM_02277 220668.lp_0161 4.52e-251 697.0 COG3559@1|root,COG3559@2|Bacteria,1TPIG@1239|Firmicutes,4H9SK@91061|Bacilli,3F4PV@33958|Lactobacillaceae 91061|Bacilli M Exporter of polyketide antibiotics - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - GHFFDFOM_02278 220668.lp_0161 4.12e-110 332.0 COG3559@1|root,COG3559@2|Bacteria,1TPIG@1239|Firmicutes,4H9SK@91061|Bacilli,3F4PV@33958|Lactobacillaceae 91061|Bacilli M Exporter of polyketide antibiotics - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - GHFFDFOM_02279 220668.lp_0160 4.24e-218 602.0 COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,4HC34@91061|Bacilli,3F4JT@33958|Lactobacillaceae 91061|Bacilli V ABC transporter ybhF_1 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 GHFFDFOM_02280 220668.lp_0159 7.14e-185 514.0 COG1028@1|root,COG1028@2|Bacteria,1TPZN@1239|Firmicutes,4HBJ8@91061|Bacilli,3F4V8@33958|Lactobacillaceae 91061|Bacilli IQ Oxidoreductase, short chain dehydrogenase reductase family protein dhrS4 - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short GHFFDFOM_02281 220668.lp_0158 3.37e-115 330.0 2DPIQ@1|root,3328X@2|Bacteria,1VFYC@1239|Firmicutes,4HNHQ@91061|Bacilli,3F7RW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - AP2 GHFFDFOM_02282 220668.lp_0156 3.59e-119 344.0 2CBBX@1|root,309KU@2|Bacteria,1U5AP@1239|Firmicutes,4IF24@91061|Bacilli,3F5EA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02283 220668.lp_0156 1.35e-46 157.0 2CBBX@1|root,309KU@2|Bacteria,1U5AP@1239|Firmicutes,4IF24@91061|Bacilli,3F5EA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02284 220668.lp_0155 3.14e-182 507.0 2CBBX@1|root,309KV@2|Bacteria,1U5AQ@1239|Firmicutes,4IF25@91061|Bacilli,3F6UY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02285 220668.lp_0154 4.14e-72 216.0 COG1695@1|root,COG1695@2|Bacteria,1U5XD@1239|Firmicutes,4IFKR@91061|Bacilli,3F6N7@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR GHFFDFOM_02286 220668.lp_0152 4.37e-167 468.0 COG2188@1|root,COG2188@2|Bacteria,1TTCD@1239|Firmicutes,4HEXQ@91061|Bacilli,3F4DA@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein - - - ko:K03492 - - - - ko00000,ko03000 - - - GntR,UTRA GHFFDFOM_02288 220668.lp_0150 2.57e-128 365.0 COG4720@1|root,COG4720@2|Bacteria,1V1GT@1239|Firmicutes,4HGAE@91061|Bacilli,3F5A7@33958|Lactobacillaceae 91061|Bacilli S UPF0397 protein - - - ko:K16924 - M00582 - - ko00000,ko00002,ko02000 3.A.1.29 - - ECF-ribofla_trS GHFFDFOM_02289 220668.lp_0149 0.0 1088.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,3F4XP@33958|Lactobacillaceae 91061|Bacilli P ABC transporter, ATP-binding protein ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 GHFFDFOM_02290 220668.lp_0148 2.21e-191 532.0 COG0619@1|root,COG0619@2|Bacteria,1TPMV@1239|Firmicutes,4HBTW@91061|Bacilli,3F3Y9@33958|Lactobacillaceae 91061|Bacilli P cobalt transport cbiQ - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iSB619.SA_RS14165 CbiQ GHFFDFOM_02291 220668.lp_0146 3.75e-267 731.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HAS5@91061|Bacilli,3F3UQ@33958|Lactobacillaceae 91061|Bacilli C Oxidoreductase - - - - - - - - - - - - Oxidored_FMN GHFFDFOM_02292 220668.lp_0145 0.0 944.0 29NM1@1|root,309J0@2|Bacteria,1U571@1239|Firmicutes,4IEYJ@91061|Bacilli,3F4ZQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02293 220668.lp_0141 1.52e-115 339.0 29PBE@1|root,30A9N@2|Bacteria,1U6D8@1239|Firmicutes,4IG4Z@91061|Bacilli,3F7N7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02294 220668.lp_0139 0.0 1147.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,4HAYH@91061|Bacilli,3F3QX@33958|Lactobacillaceae 91061|Bacilli S Myosin-crossreactive antigen l1n - 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA GHFFDFOM_02295 220668.lp_0138 3.19e-105 303.0 COG3613@1|root,COG3613@2|Bacteria,1U57V@1239|Firmicutes,4IEZ3@91061|Bacilli,3F51W@33958|Lactobacillaceae 91061|Bacilli F Nucleoside 2-deoxyribosyltransferase like - - - - - - - - - - - - Nuc_deoxyrib_tr GHFFDFOM_02296 220668.lp_0137 1.36e-211 584.0 COG0667@1|root,COG0667@2|Bacteria,1UYMV@1239|Firmicutes,4HE0W@91061|Bacilli,3F4I8@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase - - 1.1.1.65 ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 - R01708 RC00116 ko00000,ko00001,ko01000 - - - Aldo_ket_red GHFFDFOM_02297 220668.lp_0136 3.07e-204 565.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HAG6@91061|Bacilli,3FB4S@33958|Lactobacillaceae 91061|Bacilli S reductase morA - - - - - - - - - - - Aldo_ket_red GHFFDFOM_02299 220668.lp_0134 2.79e-274 751.0 COG2807@1|root,COG2807@2|Bacteria,1TP9R@1239|Firmicutes,4H9YZ@91061|Bacilli,3F52B@33958|Lactobacillaceae 91061|Bacilli P Transporter, major facilitator family protein yycB - - ko:K03449 - - - - ko00000,ko02000 2.A.1.17 - - MFS_1 GHFFDFOM_02300 220668.lp_0133 2.21e-65 200.0 COG0640@1|root,COG0640@2|Bacteria,1VF0J@1239|Firmicutes,4HP0R@91061|Bacilli,3F8E3@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 GHFFDFOM_02301 220668.lp_0132 1.8e-288 788.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,3F3T5@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein - - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,Sugar_tr GHFFDFOM_02302 60520.HR47_06140 3.28e-95 277.0 COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HPDH@91061|Bacilli,3F7DR@33958|Lactobacillaceae 91061|Bacilli O Belongs to the small heat shock protein (HSP20) family hsp1 - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 GHFFDFOM_02303 220668.lp_0128 1.05e-97 285.0 COG1846@1|root,COG1846@2|Bacteria,1U5QT@1239|Firmicutes,4IFEV@91061|Bacilli,3F6BV@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - - GHFFDFOM_02304 220668.lp_0127 1.03e-143 405.0 COG0431@1|root,COG0431@2|Bacteria,1VI8F@1239|Firmicutes,4HPT0@91061|Bacilli,3F66U@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase azo1 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0052873,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.5.1.36,1.7.1.6 ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 - R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 - - - FMN_red GHFFDFOM_02305 220668.lp_0126 2.92e-38 127.0 COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,4HRGW@91061|Bacilli,3F8BW@33958|Lactobacillaceae 91061|Bacilli KT PspC domain pspC - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC GHFFDFOM_02306 220668.lp_0125 8.08e-185 513.0 COG2820@1|root,COG2820@2|Bacteria,1V6T2@1239|Firmicutes,4HCSE@91061|Bacilli,3FBN9@33958|Lactobacillaceae 91061|Bacilli F Phosphorylase superfamily - - - - - - - - - - - - PNP_UDP_1 GHFFDFOM_02307 220668.lp_0124 0.0 1724.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase pacL1 - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase GHFFDFOM_02308 220668.lp_0122 2.94e-191 530.0 COG2267@1|root,COG2267@2|Bacteria,1UIX9@1239|Firmicutes,4ISVM@91061|Bacilli 91061|Bacilli I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 GHFFDFOM_02309 220668.lp_0121 1e-156 441.0 29NYS@1|root,309WV@2|Bacteria,1U5V7@1239|Firmicutes,4IFIU@91061|Bacilli,3F6J8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02310 220668.lp_0120 0.0 867.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease yifK - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease GHFFDFOM_02311 220668.lp_0119 3.55e-109 314.0 COG1051@1|root,COG1051@2|Bacteria,1V3T8@1239|Firmicutes,4HH2F@91061|Bacilli,3FC6R@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX GHFFDFOM_02312 220668.lp_0118 0.0 1052.0 29VC1@1|root,30GSE@2|Bacteria,1UGIJ@1239|Firmicutes,4IF7C@91061|Bacilli,3F5VP@33958|Lactobacillaceae 91061|Bacilli L HIRAN domain - - - - - - - - - - - - HIRAN GHFFDFOM_02313 220668.lp_0117 3.4e-174 486.0 COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,3F4PK@33958|Lactobacillaceae 91061|Bacilli S peptidase C26 puuD - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 GHFFDFOM_02314 220668.lp_0116 2.4e-260 716.0 COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,4HA3B@91061|Bacilli,3F4YG@33958|Lactobacillaceae 91061|Bacilli U Belongs to the purine-cytosine permease (2.A.39) family thiP - - - - - - - - - - - Transp_cyt_pur GHFFDFOM_02315 220668.lp_0115 2.68e-143 405.0 COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,3F5ZQ@33958|Lactobacillaceae 91061|Bacilli H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI GHFFDFOM_02316 220668.lp_0114 8.33e-189 525.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,3F3NA@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin GHFFDFOM_02317 220668.lp_0113 1.08e-174 488.0 COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,4HFTJ@91061|Bacilli,3F43J@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008972,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK GHFFDFOM_02318 220668.lp_0111 4.79e-225 621.0 COG0604@1|root,COG0604@2|Bacteria,1TZGF@1239|Firmicutes,4HEDQ@91061|Bacilli,3FC43@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N GHFFDFOM_02319 220668.lp_0109 3.03e-192 534.0 COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,4HAZT@91061|Bacilli,3F3Z9@33958|Lactobacillaceae 91061|Bacilli S NAD synthase larE - - ko:K06864 - - - - ko00000 - - - NAD_synthase GHFFDFOM_02320 220668.lp_0108 1.19e-170 476.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,3F4Y7@33958|Lactobacillaceae 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP GHFFDFOM_02321 220668.lp_0107 6.32e-99 287.0 COG1641@1|root,COG1641@2|Bacteria,1V4CM@1239|Firmicutes,4IBXK@91061|Bacilli,3F6BC@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function DUF111 larC2 - 4.99.1.12 ko:K09121 - - - - ko00000,ko01000 - - - DUF111 GHFFDFOM_02322 220668.lp_0106 2.03e-179 500.0 COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,4HC7I@91061|Bacilli,3F408@33958|Lactobacillaceae 91061|Bacilli S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes larC - 4.99.1.12 ko:K09121 - - - - ko00000,ko01000 - - - DUF111 GHFFDFOM_02323 220668.lp_0105 2.65e-162 456.0 COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,4HBMK@91061|Bacilli,3F526@33958|Lactobacillaceae 91061|Bacilli S AIR carboxylase larB - - ko:K06898 - - - - ko00000 - - - AIRC GHFFDFOM_02324 60520.HR47_06030 7.9e-306 833.0 COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,4HDCE@91061|Bacilli,3F3MP@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF2088) larA - 5.1.2.1 ko:K22373 ko00620,map00620 - R01450 RC00519 ko00000,ko00001,ko01000 - - - DUF2088 GHFFDFOM_02325 220668.lp_0103 1.39e-156 439.0 COG0664@1|root,COG0664@2|Bacteria,1UXDW@1239|Firmicutes,4HCRG@91061|Bacilli,3F5KR@33958|Lactobacillaceae 91061|Bacilli K Crp-like helix-turn-helix domain rcfB - - - - - - - - - - - HTH_Crp_2 GHFFDFOM_02326 220668.lp_0102 1.84e-235 647.0 COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,4IRCD@91061|Bacilli,3F4V7@33958|Lactobacillaceae 91061|Bacilli P PDGLE domain cbiM - - ko:K02007 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiM,PDGLE GHFFDFOM_02327 220668.lp_0101 9.79e-192 532.0 COG0619@1|root,COG0619@2|Bacteria,1V7YC@1239|Firmicutes,4HRFQ@91061|Bacilli,3F6UF@33958|Lactobacillaceae 91061|Bacilli P Cobalt transport protein - - - ko:K02008 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiQ GHFFDFOM_02328 220668.lp_0100 7.11e-165 462.0 COG1122@1|root,COG1122@2|Bacteria,1V16T@1239|Firmicutes,4HI15@91061|Bacilli,3F5BR@33958|Lactobacillaceae 91061|Bacilli P ABC transporter - - - ko:K02006 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - ABC_tran GHFFDFOM_02329 220668.lp_0099 1.67e-54 169.0 2BWF7@1|root,30A8B@2|Bacteria,1U6BN@1239|Firmicutes,4IG3A@91061|Bacilli,3F7J1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02330 220668.lp_0098 1.33e-184 513.0 COG1708@1|root,COG1708@2|Bacteria,1UCIC@1239|Firmicutes,4HEP7@91061|Bacilli,3F5YN@33958|Lactobacillaceae 91061|Bacilli H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin ant1 - 2.7.7.47 ko:K00984 - - - - ko00000,ko01000,ko01504 - - - DUF4111,NTP_transf_2 GHFFDFOM_02331 60520.HR47_05995 4.07e-05 45.1 2BNJN@1|root,32H8G@2|Bacteria,1U7Y8@1239|Firmicutes,4IHVK@91061|Bacilli,3FABD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02332 220668.lp_0096 4.85e-180 501.0 29NK9@1|root,309I8@2|Bacteria,1U555@1239|Firmicutes,4IEWG@91061|Bacilli,3F4QT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02333 220668.lp_0092 0.0 1075.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F46R@33958|Lactobacillaceae 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GHFFDFOM_02334 220668.lp_0091 2.38e-99 288.0 2A775@1|root,30W3A@2|Bacteria,1U501@1239|Firmicutes,4IKCQ@91061|Bacilli,3F6AF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02335 220668.lp_0089 2.14e-178 496.0 COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,4HFN2@91061|Bacilli,3F4KR@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0246 family XK27_08125 - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD GHFFDFOM_02336 220668.lp_0088 6.04e-218 600.0 COG2267@1|root,COG2267@2|Bacteria,1TRMT@1239|Firmicutes,4HE23@91061|Bacilli,3F40N@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates pepI - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 GHFFDFOM_02337 220668.lp_0085 5.98e-302 825.0 COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,4HEHY@91061|Bacilli,3F3KX@33958|Lactobacillaceae 91061|Bacilli V MATE efflux family protein mepA - - ko:K18908 - M00705 - - ko00000,ko00002,ko01504,ko02000 2.A.66.1.13 - - MatE GHFFDFOM_02338 220668.lp_0083 1.92e-67 204.0 COG0640@1|root,COG0640@2|Bacteria,1VFY4@1239|Firmicutes,4HP5T@91061|Bacilli,3FB52@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5 GHFFDFOM_02339 220668.lp_0082 1.02e-235 649.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,3F4EJ@33958|Lactobacillaceae 91061|Bacilli C nadph quinone reductase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 GHFFDFOM_02340 220668.lp_0081 1.4e-162 454.0 COG0693@1|root,COG0693@2|Bacteria,1UG8E@1239|Firmicutes,4HCBM@91061|Bacilli,3F4SD@33958|Lactobacillaceae 91061|Bacilli S DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI GHFFDFOM_02341 220668.lp_0080 4.43e-120 342.0 COG0454@1|root,COG0456@2|Bacteria,1VEEJ@1239|Firmicutes,4HP6M@91061|Bacilli,3FBDP@33958|Lactobacillaceae 91061|Bacilli K FR47-like protein yfbM - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 GHFFDFOM_02342 220668.lp_0078 5e-194 540.0 COG0697@1|root,COG0697@2|Bacteria,1V23Q@1239|Firmicutes,4HDPS@91061|Bacilli,3FBA3@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA GHFFDFOM_02343 220668.lp_0077 1.84e-109 317.0 28P7V@1|root,2ZC22@2|Bacteria,1V2CT@1239|Firmicutes,4HG6A@91061|Bacilli,3F6CH@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function - - - - - - - - - - - - DUF1835,DUF3658 GHFFDFOM_02344 220668.lp_0077 6.1e-38 132.0 28P7V@1|root,2ZC22@2|Bacteria,1V2CT@1239|Firmicutes,4HG6A@91061|Bacilli,3F6CH@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function - - - - - - - - - - - - DUF1835,DUF3658 GHFFDFOM_02345 220668.lp_0076 0.0 1325.0 COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,4HAS9@91061|Bacilli,3F4B4@33958|Lactobacillaceae 91061|Bacilli J elongation factor G fusA1 - - - - - - - - - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU GHFFDFOM_02346 220668.lp_0075 6.65e-152 427.0 COG1182@1|root,COG1182@2|Bacteria,1V2AQ@1239|Firmicutes,4HGK5@91061|Bacilli,3F580@33958|Lactobacillaceae 91061|Bacilli C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 GHFFDFOM_02347 220668.lp_0074 5.58e-219 604.0 COG2378@1|root,COG2378@2|Bacteria,1U8E4@1239|Firmicutes,4IQQI@91061|Bacilli,3FBID@33958|Lactobacillaceae 91061|Bacilli K WYL domain - - - - - - - - - - - - HTH_11,WYL GHFFDFOM_02348 220668.lp_0073 3.06e-165 461.0 COG0518@1|root,COG0518@2|Bacteria,1UAH0@1239|Firmicutes,4HHTX@91061|Bacilli,3F4AV@33958|Lactobacillaceae 91061|Bacilli F glutamine amidotransferase - - - - - - - - - - - - GATase GHFFDFOM_02349 220668.lp_0072 1.65e-106 306.0 COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli,3F7EV@33958|Lactobacillaceae 91061|Bacilli S ASCH - - - - - - - - - - - - ASCH GHFFDFOM_02350 60520.HR47_05895 0.0 878.0 COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,4HA4I@91061|Bacilli,3F5BC@33958|Lactobacillaceae 91061|Bacilli Q 4-hydroxyphenylacetate hpaH - 1.14.14.8,1.14.14.9 ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 - R02698,R03299,R09517 RC00046 ko00000,ko00001,ko01000 - - - HpaB,HpaB_N GHFFDFOM_02351 220668.lp_0069 2.79e-174 486.0 COG2365@1|root,COG2365@2|Bacteria,1V6Q5@1239|Firmicutes,4HJKY@91061|Bacilli,3F5X1@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family ptp1 - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 GHFFDFOM_02352 220668.lp_0068 0.0 866.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,4HU4D@91061|Bacilli,3F4FR@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE,ThrE_2 GHFFDFOM_02353 220668.lp_0067 2.19e-248 681.0 COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,4HC4Y@91061|Bacilli,3F4NH@33958|Lactobacillaceae 91061|Bacilli M Linear amide C-N hydrolase, choloylglycine hydrolase family protein pva1 - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH GHFFDFOM_02354 220668.lp_0066 1.56e-154 434.0 COG0637@1|root,COG0637@2|Bacteria,1UY8N@1239|Firmicutes,4HF3K@91061|Bacilli,3F4ST@33958|Lactobacillaceae 91061|Bacilli S beta-phosphoglucomutase pgmB - 5.4.2.6 ko:K01838 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - HAD_2 GHFFDFOM_02355 220668.lp_0063 0.0 1005.0 COG2508@1|root,COG2508@2|Bacteria,1TRRH@1239|Firmicutes,4HQKK@91061|Bacilli,3F5KD@33958|Lactobacillaceae 91061|Bacilli QT PucR C-terminal helix-turn-helix domain - - - - - - - - - - - - HTH_30 GHFFDFOM_02356 220668.lp_0062 5.07e-157 440.0 COG0778@1|root,COG0778@2|Bacteria,1UYJU@1239|Firmicutes,4HBVQ@91061|Bacilli,3F4H1@33958|Lactobacillaceae 91061|Bacilli C Nitroreductase family ydgI - - - - - - - - - - - Nitroreductase GHFFDFOM_02357 220668.lp_0061 5.5e-202 559.0 COG4689@1|root,COG4689@2|Bacteria,1VW7Z@1239|Firmicutes,4I17W@91061|Bacilli,3F5RQ@33958|Lactobacillaceae 91061|Bacilli Q Acetoacetate decarboxylase (ADC) adc - 4.1.1.4 ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 M00088 R01366 RC00040 ko00000,ko00001,ko00002,ko01000 - - - ADC GHFFDFOM_02358 220668.lp_0060 4.74e-210 580.0 COG4221@1|root,COG4221@2|Bacteria,1UI5T@1239|Firmicutes,4HI5J@91061|Bacilli,3FBSB@33958|Lactobacillaceae 91061|Bacilli S KR domain - - - - - - - - - - - - adh_short GHFFDFOM_02359 220668.lp_0059 1.82e-97 283.0 COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,4HH49@91061|Bacilli,3F6GQ@33958|Lactobacillaceae 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc GHFFDFOM_02360 220668.lp_0058 8.35e-94 274.0 COG0716@1|root,COG0716@2|Bacteria,1VCK0@1239|Firmicutes,4I1W9@91061|Bacilli,3F6FQ@33958|Lactobacillaceae 91061|Bacilli C FMN binding - - - - - - - - - - - - Flavodoxin_3 GHFFDFOM_02361 220668.lp_0057 3.43e-203 563.0 COG0583@1|root,COG0583@2|Bacteria,1V5VW@1239|Firmicutes,4HHDY@91061|Bacilli,3F5D2@33958|Lactobacillaceae 91061|Bacilli K LysR family - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_02362 220668.lp_0056 0.0 894.0 COG0471@1|root,COG0471@2|Bacteria,1TSGE@1239|Firmicutes,4HDE4@91061|Bacilli,3F4RH@33958|Lactobacillaceae 91061|Bacilli P Sodium:sulfate symporter transmembrane region - - - ko:K03319 - - - - ko00000 2.A.47 - - Na_sulph_symp GHFFDFOM_02363 220668.lp_0055 0.0 1581.0 COG0431@1|root,COG1053@1|root,COG3976@1|root,COG0431@2|Bacteria,COG1053@2|Bacteria,COG3976@2|Bacteria,1UZHI@1239|Firmicutes,4I3MZ@91061|Bacilli,3F4A4@33958|Lactobacillaceae 91061|Bacilli C FMN_bind - - - - - - - - - - - - FAD_binding_2,FMN_bind,FMN_red GHFFDFOM_02364 220668.lp_0053 1.57e-150 423.0 2C009@1|root,32UHI@2|Bacteria,1V4P1@1239|Firmicutes,4HH50@91061|Bacilli,3F5IU@33958|Lactobacillaceae 91061|Bacilli S Elongation factor G-binding protein, N-terminal - - - - - - - - - - - - EF-G-binding_N,FBP_C GHFFDFOM_02365 60520.HR47_05825 2.02e-85 251.0 COG0720@1|root,COG0720@2|Bacteria,1VEAX@1239|Firmicutes,4HZ0J@91061|Bacilli,3F7HK@33958|Lactobacillaceae 91061|Bacilli H 6-pyruvoyl tetrahydropterin synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS GHFFDFOM_02366 220668.lp_0050 2.72e-156 438.0 COG0778@1|root,COG0778@2|Bacteria,1V6AG@1239|Firmicutes,4HN5N@91061|Bacilli,3F6YM@33958|Lactobacillaceae 91061|Bacilli C nitroreductase pnb - - - - - - - - - - - Nitroreductase GHFFDFOM_02367 220668.lp_0048 1.82e-116 335.0 COG1573@1|root,COG1573@2|Bacteria,1V1F8@1239|Firmicutes,4HFVS@91061|Bacilli,3F4WH@33958|Lactobacillaceae 91061|Bacilli L Uracil-DNA glycosylase ung2 - - - - - - - - - - - UDG GHFFDFOM_02368 60520.HR47_10330 2.75e-112 329.0 COG0730@1|root,COG0730@2|Bacteria,1VR9G@1239|Firmicutes,4HV4W@91061|Bacilli,3F3TR@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE GHFFDFOM_02371 1220551.SCHR_10280 1.29e-05 48.1 COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,4HB3H@91061|Bacilli,4GYIH@90964|Staphylococcaceae 91061|Bacilli L Recombinase - - - ko:K06400 - - - - ko00000 - - - Ogr_Delta,Recombinase,Resolvase,Zn_ribbon_recom GHFFDFOM_02372 1158608.I583_02505 8.64e-180 524.0 COG0433@1|root,COG0433@2|Bacteria,1TPQN@1239|Firmicutes,4HC61@91061|Bacilli 91061|Bacilli S cog cog0433 - - - ko:K06915 - - - - ko00000 - - - DUF853,DUF87 GHFFDFOM_02373 1114972.AUAW01000013_gene1054 6.71e-158 459.0 arCOG14100@1|root,2Z924@2|Bacteria,1VEF7@1239|Firmicutes,4HI26@91061|Bacilli,3FA0Z@33958|Lactobacillaceae 91061|Bacilli S SIR2-like domain - - - - - - - - - - - - SIR2_2 GHFFDFOM_02374 220668.lp_0045 6.08e-107 308.0 COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli,3F3YX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase GHFFDFOM_02375 220668.lp_0043 1.5e-253 701.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,3F45X@33958|Lactobacillaceae 91061|Bacilli O serine protease htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 GHFFDFOM_02376 220668.lp_0041 1.71e-200 554.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,3F3S4@33958|Lactobacillaceae 91061|Bacilli S domain protein vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 GHFFDFOM_02377 220668.lp_0039 3.54e-195 542.0 COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,3F3PV@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycI - - - - - - - - - - - YycI GHFFDFOM_02378 220668.lp_0038 3.55e-313 853.0 COG4863@1|root,COG4863@2|Bacteria,1V32Y@1239|Firmicutes,4HG2Q@91061|Bacilli,3F4HR@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycH - - - - - - - - - - - YycH GHFFDFOM_02379 220668.lp_0037 0.0 1186.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,3F45G@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 GHFFDFOM_02380 1136177.KCA1_0029 2.22e-169 473.0 COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,3F4FB@33958|Lactobacillaceae 91061|Bacilli K response regulator yycF GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07668 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C GHFFDFOM_02382 220668.lp_0032 2.54e-50 159.0 2CH90@1|root,2ZP4M@2|Bacteria,1W1QU@1239|Firmicutes,4I01G@91061|Bacilli,3F7JH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02383 220668.lp_0031 4.37e-43 140.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4IG6G@91061|Bacilli,3F7R5@33958|Lactobacillaceae 91061|Bacilli K Cold shock protein domain cspL - - ko:K03704 - - - - ko00000,ko03000 - - - CSD GHFFDFOM_02384 220668.lp_0030 3.21e-104 301.0 COG3871@1|root,COG3871@2|Bacteria,1V1KZ@1239|Firmicutes,4I1P9@91061|Bacilli,3F7W7@33958|Lactobacillaceae 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx GHFFDFOM_02385 220668.lp_0028 0.0 1826.0 COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HD7Z@91061|Bacilli,3F4TB@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolase family 65 central catalytic domain trePP - 2.4.1.216,2.4.1.8 ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 - R01555 RC00049 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m GHFFDFOM_02386 220668.lp_0027 9.02e-154 432.0 COG0637@1|root,COG0637@2|Bacteria,1UY8N@1239|Firmicutes,4HF3K@91061|Bacilli,3F4ST@33958|Lactobacillaceae 91061|Bacilli S beta-phosphoglucomutase pgmB - 5.4.2.6 ko:K01838 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - HAD_2 GHFFDFOM_02387 220668.lp_0026 2.4e-183 509.0 COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,3F49K@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 GHFFDFOM_02389 220668.lp_0025 0.0 1272.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,3F41N@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family malZ - 3.2.1.20,3.2.1.41 ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 - R00028,R00801,R00802,R02111,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - CBM48,GH13,GH31 - Alpha-amylase,Alpha-amylase_N GHFFDFOM_02390 220668.lp_0024 0.0 1603.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,3F4Z1@33958|Lactobacillaceae 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase GHFFDFOM_02391 220668.lp_0023 0.0 963.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,3F3PP@33958|Lactobacillaceae 91061|Bacilli F Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 GHFFDFOM_02392 220668.lp_0022 3.49e-269 738.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli,3F58E@33958|Lactobacillaceae 91061|Bacilli G Nucleotidyl transferase glgD - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase GHFFDFOM_02393 220668.lp_0021 6.65e-282 769.0 COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli,3F4IA@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase GHFFDFOM_02394 220668.lp_0020 0.0 1324.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli,3F4KT@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 GHFFDFOM_02396 220668.lp_0018 0.0 979.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GHFFDFOM_02398 220668.lp_0017 1.88e-291 796.0 COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli,3F3W7@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU13130 Aldedh GHFFDFOM_02399 220668.lp_0016 9e-184 511.0 COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli,3F4E1@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase GHFFDFOM_02400 220668.lp_0015 7.88e-286 781.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,3F4F9@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator yttB - - - - - - - - - - - MFS_1 GHFFDFOM_02401 60520.HR47_10575 3.15e-315 862.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,3F4MW@33958|Lactobacillaceae 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C GHFFDFOM_02402 220668.lp_0013 3.44e-95 278.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,3F68P@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N GHFFDFOM_02403 220668.lp_0012 0.0 1290.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,3F3TY@33958|Lactobacillaceae 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 GHFFDFOM_02404 60520.HR47_00325 3.75e-122 348.0 COG2818@1|root,COG2818@2|Bacteria,1VVUW@1239|Firmicutes,4HW42@91061|Bacilli,3F5KH@33958|Lactobacillaceae 91061|Bacilli L glycosylase tag2 - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco GHFFDFOM_02405 60520.HR47_00330 1.57e-261 718.0 COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,3F4SS@33958|Lactobacillaceae 91061|Bacilli H dihydropteroate synthase folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind GHFFDFOM_02406 220668.lp_3295 1.59e-131 374.0 COG0127@1|root,COG0127@2|Bacteria,1VWAB@1239|Firmicutes,4HWPY@91061|Bacilli,3F4R5@33958|Lactobacillaceae 91061|Bacilli F Ham1 family folQ - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like GHFFDFOM_02407 220668.lp_3296 1.03e-314 858.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,3F3ZR@33958|Lactobacillaceae 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M GHFFDFOM_02408 220668.lp_3297 3.64e-134 380.0 COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli,3F4A0@33958|Lactobacillaceae 91061|Bacilli F GTP cyclohydrolase 1 folE - 2.7.6.3,3.5.4.16 ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R03503,R04639,R05046,R05048 RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI,HPPK GHFFDFOM_02409 220668.lp_3298 1.59e-121 346.0 COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,3F6SY@33958|Lactobacillaceae 91061|Bacilli H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK GHFFDFOM_02410 220668.lp_3299 3.92e-83 245.0 COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4HKKK@91061|Bacilli,3F7N6@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB GHFFDFOM_02411 220668.lp_3301 4.26e-109 315.0 COG1286@1|root,COG1286@2|Bacteria,1V7U0@1239|Firmicutes,4HIUU@91061|Bacilli,3F643@33958|Lactobacillaceae 91061|Bacilli S Colicin V production protein cvpA - - - - - - - - - - - Colicin_V GHFFDFOM_02412 220668.lp_3302 5.61e-216 596.0 COG0803@1|root,COG0803@2|Bacteria,1V110@1239|Firmicutes,4HE71@91061|Bacilli,3FC74@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA GHFFDFOM_02413 220668.lp_3303 8.83e-317 865.0 COG0477@1|root,COG2814@2|Bacteria,1TS0Y@1239|Firmicutes,4HEMR@91061|Bacilli,3F4GE@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 GHFFDFOM_02415 220668.lp_3305 1.07e-52 166.0 2DKSV@1|root,30APG@2|Bacteria,1U6Y5@1239|Firmicutes,4IGSB@91061|Bacilli,3F8PU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02416 1214166.ALLG01000015_gene1986 2.09e-123 387.0 COG4694@1|root,COG4694@2|Bacteria,1TT67@1239|Firmicutes,4HCP2@91061|Bacilli 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_13 GHFFDFOM_02417 913848.AELK01000078_gene1665 0.0 2028.0 COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,4HB5A@91061|Bacilli,3F50Q@33958|Lactobacillaceae 91061|Bacilli V Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - EcoR124_C,HSDR_N,ResIII GHFFDFOM_02418 1423816.BACQ01000038_gene1594 0.0 1056.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli,3F4HM@33958|Lactobacillaceae 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase GHFFDFOM_02419 1140002.I570_02051 1.1e-127 380.0 COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes,4HFAV@91061|Bacilli,4B379@81852|Enterococcaceae 91061|Bacilli V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S GHFFDFOM_02420 1133569.AHYZ01000017_gene1019 3.72e-103 308.0 COG4227@1|root,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,4HKTX@91061|Bacilli,3F5I0@33958|Lactobacillaceae 91061|Bacilli L Psort location Cytoplasmic, score - - - - - - - - - - - - - GHFFDFOM_02421 220668.lp_1165 1.93e-210 581.0 COG4814@1|root,COG4814@2|Bacteria,1V8NG@1239|Firmicutes,4HJ22@91061|Bacilli,3F41V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 GHFFDFOM_02422 220668.lp_1164 5.73e-316 860.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HE28@91061|Bacilli,3FC6Y@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane pts14C - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC GHFFDFOM_02423 220668.lp_1163 3.93e-99 288.0 COG0589@1|root,COG0589@2|Bacteria,1UG0Z@1239|Firmicutes,4IF22@91061|Bacilli,3F5E2@33958|Lactobacillaceae 91061|Bacilli T Universal stress protein family - - - - - - - - - - - - Usp GHFFDFOM_02425 220668.lp_1162 5.62e-316 861.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,3F4K8@33958|Lactobacillaceae 91061|Bacilli L DEAD DEAH box helicase yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C GHFFDFOM_02426 220668.lp_1161 1.94e-245 673.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HCIG@91061|Bacilli,3F4EV@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase mocA - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C GHFFDFOM_02427 1136177.KCA1_0934 6.22e-43 139.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4IG8P@91061|Bacilli,3F7VH@33958|Lactobacillaceae 91061|Bacilli K 'Cold-shock' DNA-binding domain cspP - - ko:K03704 - - - - ko00000,ko03000 - - - CSD GHFFDFOM_02428 220668.lp_1159 7.34e-83 244.0 2EGZM@1|root,33ARR@2|Bacteria,1VNS7@1239|Firmicutes,4HSZW@91061|Bacilli,3F83W@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4828) - - - - - - - - - - - - DUF4828 GHFFDFOM_02429 220668.lp_1158 4.68e-187 519.0 COG3757@1|root,COG3757@2|Bacteria,1V484@1239|Firmicutes,4HQWA@91061|Bacilli,3F4K0@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 lys - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25 GHFFDFOM_02430 220668.lp_1157 5.63e-196 545.0 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,3F42G@33958|Lactobacillaceae 91061|Bacilli K rpiR family gntR - - - - - - - - - - - HTH_6,SIS GHFFDFOM_02431 220668.lp_1156 2.51e-147 418.0 COG4814@1|root,COG4814@2|Bacteria,1V8NG@1239|Firmicutes,4HJ22@91061|Bacilli,3F41V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 GHFFDFOM_02432 60520.HR47_10910 0.0 1641.0 COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,4HC2J@91061|Bacilli,3F3TZ@33958|Lactobacillaceae 91061|Bacilli G Phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N GHFFDFOM_02433 1423734.JCM14202_2816 3.44e-200 554.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli,3F46G@33958|Lactobacillaceae 91061|Bacilli L Integrase core domain is18 - - - - - - - - - - - HTH_21,rve GHFFDFOM_02434 1074451.CRL705_1644 2.48e-52 164.0 COG2963@1|root,COG2963@2|Bacteria,1VIEV@1239|Firmicutes,4HJSC@91061|Bacilli,3F6X7@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 GHFFDFOM_02435 1291743.LOSG293_220250 2.01e-259 726.0 COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,3F4W6@33958|Lactobacillaceae 91061|Bacilli L This gene contains a nucleotide ambiguity which may be the result of a sequencing error traI - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim,Toprim_Crpt,zf-C4_Topoisom GHFFDFOM_02436 1291743.LOSG293_220240 5.72e-85 251.0 29NXD@1|root,309VH@2|Bacteria,1U5SV@1239|Firmicutes,4IFGT@91061|Bacilli,3F6FI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02437 1045004.OKIT_0536 2.09e-151 428.0 2EN0Y@1|root,33FP4@2|Bacteria,1VPIB@1239|Firmicutes,4HRWI@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02438 1291743.LOSG293_220100 0.0 1304.0 COG0507@1|root,COG0507@2|Bacteria,1VQWC@1239|Firmicutes,4HD6B@91061|Bacilli,3F4DP@33958|Lactobacillaceae 91061|Bacilli L MobA MobL family protein traA - - - - - - - - - - - MobA_MobL GHFFDFOM_02439 1423734.JCM14202_2802 6.89e-37 124.0 29P8B@1|root,30A6E@2|Bacteria,1U69C@1239|Firmicutes,4IG0H@91061|Bacilli,3F7CM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02440 1423743.JCM14108_3282 4.05e-53 167.0 2EJES@1|root,33D5R@2|Bacteria,1VKZC@1239|Firmicutes,4HRGI@91061|Bacilli,3F6Y2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02441 1384049.CD29_19250 0.0 1246.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3IWQZ@400634|Lysinibacillus 91061|Bacilli P Cadmium transporter - - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase GHFFDFOM_02442 935836.JAEL01000040_gene4773 2.06e-70 213.0 COG0640@1|root,COG0640@2|Bacteria,1VFNB@1239|Firmicutes,4HQ6G@91061|Bacilli,1ZQGP@1386|Bacillus 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor cadC - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_5 GHFFDFOM_02443 568703.LGG_00020 2.35e-243 668.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve GHFFDFOM_02445 1291743.LOSG293_360110 1.01e-130 372.0 COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,4HCFF@91061|Bacilli,3F429@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed pinR1 - - - - - - - - - - - HTH_7,Resolvase GHFFDFOM_02446 1138822.PL11_10090 8.73e-190 526.0 COG1192@1|root,COG1192@2|Bacteria,1V6Q6@1239|Firmicutes,4HINH@91061|Bacilli,3F477@33958|Lactobacillaceae 91061|Bacilli D CobQ CobB MinD ParA nucleotide binding domain protein - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 GHFFDFOM_02448 797515.HMPREF9103_01395 6.22e-79 235.0 29PWH@1|root,30AUV@2|Bacteria,1U74S@1239|Firmicutes,4IGZE@91061|Bacilli,3F8Z3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02449 1423734.JCM14202_2807 2.49e-163 468.0 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,3F55E@33958|Lactobacillaceae 91061|Bacilli S Replication initiator protein A repA - - - - - - - - - - - RepA_N GHFFDFOM_02450 1423775.BAMN01000043_gene24 2.41e-200 558.0 COG5527@1|root,COG5527@2|Bacteria,1V8VU@1239|Firmicutes,4HWIQ@91061|Bacilli,3F45C@33958|Lactobacillaceae 91061|Bacilli L Initiator Replication protein - - - - - - - - - - - - Rep_3 GHFFDFOM_02451 1423806.JCM15457_2554 1.13e-77 234.0 2DJVC@1|root,307G3@2|Bacteria,1TVN0@1239|Firmicutes,4I3N8@91061|Bacilli,3F8UK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02452 1423806.JCM15457_2555 1.46e-261 717.0 COG0775@1|root,COG0775@2|Bacteria,1UIMI@1239|Firmicutes 1239|Firmicutes F SEFIR domain protein - - - - - - - - - - - - SEFIR GHFFDFOM_02453 1423806.JCM15457_2556 1.29e-205 570.0 COG2253@1|root,COG2253@2|Bacteria,1VY09@1239|Firmicutes 1239|Firmicutes S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii GHFFDFOM_02454 1423806.JCM15457_2557 5.34e-133 384.0 COG5340@1|root,COG5340@2|Bacteria,1UZGU@1239|Firmicutes 1239|Firmicutes K Psort location Cytoplasmic, score - - - - - - - - - - - - AbiEi_1 GHFFDFOM_02455 1154757.Q5C_07660 3.25e-188 524.0 28P3D@1|root,2ZBZ3@2|Bacteria,1U484@1239|Firmicutes,4IDZ8@91061|Bacilli,4AY20@81850|Leuconostocaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02456 46256.BBIK01000007_gene1265 6.14e-133 378.0 COG0582@1|root,COG0582@2|Bacteria,1VEIE@1239|Firmicutes,4HK3N@91061|Bacilli,4AX2E@81850|Leuconostocaceae 91061|Bacilli L Phage integrase family - - - - - - - - - - - - Phage_integrase GHFFDFOM_02457 1138822.PL11_10600 3.66e-82 243.0 2A0U1@1|root,30NYT@2|Bacteria,1TX67@1239|Firmicutes,4I62R@91061|Bacilli,3F6CW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02458 387344.LVIS_2250 3.36e-90 265.0 29QGW@1|root,30BGA@2|Bacteria,1U82U@1239|Firmicutes,4II08@91061|Bacilli,3FAGK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02459 387344.LVIS_2249 9.97e-36 121.0 COG1476@1|root,COG1476@2|Bacteria,1VEM3@1239|Firmicutes,4HNUV@91061|Bacilli 91061|Bacilli K Transcriptional - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 GHFFDFOM_02460 1423815.BACR01000051_gene2357 2.45e-44 143.0 2DKQ8@1|root,30AAT@2|Bacteria,1U6EN@1239|Firmicutes,4IG6F@91061|Bacilli,3F7R3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02461 220668.lp_3466 1.62e-63 206.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans GHFFDFOM_02462 220668.lp_3468 0.0 1206.0 COG2190@1|root,COG2211@1|root,COG2190@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HCDS@91061|Bacilli,3F3P7@33958|Lactobacillaceae 91061|Bacilli G Transporter lacS - - ko:K11104,ko:K16209 - - - - ko00000,ko02000 2.A.2.1,2.A.2.2 - - MFS_2,PTS_EIIA_1 GHFFDFOM_02463 220668.lp_3469 0.0 1077.0 COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,4HARI@91061|Bacilli,3F3PC@33958|Lactobacillaceae 91061|Bacilli G -beta-galactosidase lacA - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M GHFFDFOM_02464 1423816.BACQ01000069_gene2568 5.24e-73 219.0 COG3293@1|root,COG3293@2|Bacteria,1VXWA@1239|Firmicutes,4HXG3@91061|Bacilli,3F7AF@33958|Lactobacillaceae 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_2 GHFFDFOM_02465 1122149.BACN01000095_gene1995 4.61e-68 208.0 COG3293@1|root,COG3293@2|Bacteria,1U5ZT@1239|Firmicutes,4IFNT@91061|Bacilli,3F6RW@33958|Lactobacillaceae 91061|Bacilli L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 GHFFDFOM_02466 220668.lp_3483 0.0 1304.0 COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,4HANW@91061|Bacilli,3F4EI@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 2 family lacL - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N GHFFDFOM_02467 1400520.LFAB_17215 8.85e-85 249.0 COG4633@1|root,COG4633@2|Bacteria,1VE0E@1239|Firmicutes,4HMFJ@91061|Bacilli,3F6KW@33958|Lactobacillaceae 91061|Bacilli S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 GHFFDFOM_02468 1400520.LFAB_17210 5.01e-61 187.0 COG4633@1|root,COG4633@2|Bacteria,1U82Z@1239|Firmicutes,4II0D@91061|Bacilli,3FAGS@33958|Lactobacillaceae 91061|Bacilli S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 GHFFDFOM_02469 1400520.LFAB_17205 0.0 1205.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,3F4IX@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase copA - 3.6.3.3,3.6.3.5,3.6.3.54 ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5,3.A.3.6 - - E1-E2_ATPase,Hydrolase GHFFDFOM_02470 877455.Metbo_0009 2.57e-06 50.8 COG2217@1|root,arCOG02763@1|root,arCOG02764@1|root,arCOG01576@2157|Archaea,arCOG02763@2157|Archaea,arCOG02764@2157|Archaea,2XT3T@28890|Euryarchaeota,23NJY@183925|Methanobacteria 183925|Methanobacteria P ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase GHFFDFOM_02471 315749.Bcer98_0503 3.71e-88 266.0 COG0745@1|root,COG0745@2|Bacteria,1TS8Z@1239|Firmicutes,4HC86@91061|Bacilli,1ZB3W@1386|Bacillus 91061|Bacilli KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C GHFFDFOM_02472 1400520.LFAB_17190 0.0 884.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4H9UD@91061|Bacilli,3F3Z4@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA GHFFDFOM_02473 1400520.LFAB_17185 5.93e-197 545.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,3F42N@33958|Lactobacillaceae 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT GHFFDFOM_02475 1139219.I569_00569 4.23e-07 49.3 2BSBS@1|root,32MDK@2|Bacteria,1U295@1239|Firmicutes,4IBTQ@91061|Bacilli,4B3ZD@81852|Enterococcaceae 91061|Bacilli S Protein of unknown function (DUF2933) - - - - - - - - - - - - DUF2933 GHFFDFOM_02476 1400520.LFAB_17170 1.23e-129 376.0 COG5434@1|root,COG5434@2|Bacteria,1TQXN@1239|Firmicutes,4HBHT@91061|Bacilli,3F4Y5@33958|Lactobacillaceae 91061|Bacilli M Protein of unknown function (DUF3737) - - - - - - - - - - - - DUF3737 GHFFDFOM_02477 1138822.PL11_10555 4.64e-19 81.3 COG0454@1|root,COG0456@2|Bacteria,1V8AJ@1239|Firmicutes,4HPGU@91061|Bacilli,3F6YY@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 GHFFDFOM_02478 1133569.AHYZ01000017_gene1019 1.71e-245 677.0 COG4227@1|root,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,4HKTX@91061|Bacilli,3F5I0@33958|Lactobacillaceae 91061|Bacilli L Psort location Cytoplasmic, score - - - - - - - - - - - - - GHFFDFOM_02479 1122149.BACN01000143_gene320 2.16e-43 141.0 29P8A@1|root,30A6D@2|Bacteria,1U69B@1239|Firmicutes,4IG0G@91061|Bacilli,3F7CJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02480 1291743.LOSG293_220250 0.0 1345.0 COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,3F4W6@33958|Lactobacillaceae 91061|Bacilli L This gene contains a nucleotide ambiguity which may be the result of a sequencing error traI - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim,Toprim_Crpt,zf-C4_Topoisom GHFFDFOM_02481 1423816.BACQ01000038_gene1588 8.47e-87 256.0 29NXD@1|root,309VH@2|Bacteria,1U5SV@1239|Firmicutes,4IFGT@91061|Bacilli,3F6FI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02482 1045004.OKIT_0536 6.61e-193 536.0 2EN0Y@1|root,33FP4@2|Bacteria,1VPIB@1239|Firmicutes,4HRWI@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02483 1291743.LOSG293_220220 1.56e-81 242.0 2BAF6@1|root,323VN@2|Bacteria,1UQAF@1239|Firmicutes,4IFGF@91061|Bacilli,3F6F2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02484 908339.HMPREF9265_1755 0.0 955.0 COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,4H9ZN@91061|Bacilli,3F4S3@33958|Lactobacillaceae 91061|Bacilli U TraM recognition site of TraD and TraG traK - - ko:K03205 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T4SS-DNA_transf GHFFDFOM_02485 1291743.LOSG293_220200 5.66e-106 306.0 2AC4N@1|root,311NX@2|Bacteria,1U59I@1239|Firmicutes,4IF0X@91061|Bacilli,3F59S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02486 1138822.PL11_10630 2.98e-29 108.0 COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4IEJ7@91061|Bacilli,3F4SP@33958|Lactobacillaceae 91061|Bacilli L Integrase - - - - - - - - - - - - Phage_integrase GHFFDFOM_02487 1423815.BACR01000049_gene2337 4.41e-68 209.0 COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4IEJ7@91061|Bacilli,3F4SP@33958|Lactobacillaceae 91061|Bacilli L Integrase - - - - - - - - - - - - Phage_integrase GHFFDFOM_02488 1423815.BACR01000049_gene2336 2.22e-59 182.0 COG2336@1|root,COG2336@2|Bacteria,1VEM8@1239|Firmicutes,4HRUZ@91061|Bacilli,3F70N@33958|Lactobacillaceae 91061|Bacilli T Antidote-toxin recognition MazE, bacterial antitoxin - - - ko:K07172 - - - - ko00000,ko02048 - - - MazE_antitoxin GHFFDFOM_02489 1423815.BACR01000049_gene2335 2.64e-75 225.0 COG2337@1|root,COG2337@2|Bacteria,1VBXM@1239|Firmicutes,4HM83@91061|Bacilli,3F6S1@33958|Lactobacillaceae 91061|Bacilli T PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin GHFFDFOM_02491 60520.HR47_09180 4.34e-34 124.0 2DI7E@1|root,3028I@2|Bacteria,1U78W@1239|Firmicutes,4IH3R@91061|Bacilli,3F94R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF536 GHFFDFOM_02494 220668.lp_2871 3.34e-193 537.0 COG0583@1|root,COG0583@2|Bacteria,1TT5B@1239|Firmicutes,4HK1M@91061|Bacilli,3F5CC@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_02495 220668.lp_2872 1.12e-84 252.0 COG0702@1|root,COG0702@2|Bacteria,1UJSC@1239|Firmicutes,4HGYK@91061|Bacilli,3F60E@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10 GHFFDFOM_02496 220668.lp_2872 7.25e-16 73.6 COG0702@1|root,COG0702@2|Bacteria,1UJSC@1239|Firmicutes,4HGYK@91061|Bacilli,3F60E@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10 GHFFDFOM_02497 220668.lp_2873 2.03e-248 682.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,3F42F@33958|Lactobacillaceae 91061|Bacilli E alcohol dehydrogenase adh2 - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N GHFFDFOM_02498 220668.lp_2874 1.18e-193 538.0 COG1028@1|root,COG1028@2|Bacteria,1TSJI@1239|Firmicutes,4HG70@91061|Bacilli,3F5I6@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 GHFFDFOM_02499 220668.lp_2876 2.21e-46 149.0 28UH9@1|root,2ZGN0@2|Bacteria,1W65H@1239|Firmicutes,4I0DI@91061|Bacilli,3F8A7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02500 220668.lp_2877 2.1e-99 288.0 COG0589@1|root,COG0589@2|Bacteria,1V8UY@1239|Firmicutes,4HK2J@91061|Bacilli,3F6N5@33958|Lactobacillaceae 91061|Bacilli T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp GHFFDFOM_02501 220668.lp_2878 1.04e-124 356.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,3F47V@33958|Lactobacillaceae 91061|Bacilli S Maltose O-acetyltransferase maa - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - CM_2,Hexapep,Hexapep_2,Mac GHFFDFOM_02502 220668.lp_2879 7.47e-164 458.0 COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli,3F4NI@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase ysaA - 3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287 RC00017,RC00697 ko00000,ko00001,ko01000 - - - HAD_2 GHFFDFOM_02503 220668.lp_2885 1.85e-81 246.0 29QKQ@1|root,30BKC@2|Bacteria,1U89N@1239|Firmicutes,4II7K@91061|Bacilli,3FAQV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02504 220668.lp_2887 1.52e-130 371.0 COG2085@1|root,COG2085@2|Bacteria,1VW6H@1239|Firmicutes,4HWI6@91061|Bacilli,3F6QU@33958|Lactobacillaceae 91061|Bacilli S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored GHFFDFOM_02505 220668.lp_2888 2.84e-284 776.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F4JX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase, class I patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 GHFFDFOM_02506 220668.lp_2889 1.86e-132 384.0 COG5434@1|root,COG5434@2|Bacteria,1TQXN@1239|Firmicutes,4HBHT@91061|Bacilli,3F4Y5@33958|Lactobacillaceae 91061|Bacilli M Protein of unknown function (DUF3737) - - - - - - - - - - - - DUF3737 GHFFDFOM_02507 220668.lp_2890 2.02e-246 676.0 COG0667@1|root,COG0667@2|Bacteria,1TQJC@1239|Firmicutes,4HC0W@91061|Bacilli,3FB4P@33958|Lactobacillaceae 91061|Bacilli C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red GHFFDFOM_02509 220668.lp_2893 0.0 1149.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran GHFFDFOM_02510 220668.lp_2894 0.0 1117.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlA - - ko:K06148,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran GHFFDFOM_02511 60520.HR47_00050 2.23e-314 858.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 GHFFDFOM_02514 60520.HR47_01460 6.17e-317 934.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,3F3Y3@33958|Lactobacillaceae 91061|Bacilli V domain protein yhgE - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 GHFFDFOM_02515 220668.lp_2902 1.59e-143 405.0 COG1309@1|root,COG1309@2|Bacteria,1VEM5@1239|Firmicutes,4HQRV@91061|Bacilli,3F66Z@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator (TetR family) - - - - - - - - - - - - TetR_C_8,TetR_N GHFFDFOM_02516 220668.lp_2903 6.88e-71 213.0 COG0640@1|root,COG0640@2|Bacteria,1VFY4@1239|Firmicutes,4HP5T@91061|Bacilli,3F6VK@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5 GHFFDFOM_02517 220668.lp_2906 1.66e-199 555.0 COG2169@1|root,COG2169@2|Bacteria,1V4X2@1239|Firmicutes,4HIF5@91061|Bacilli,3F3Y8@33958|Lactobacillaceae 91061|Bacilli F DNA RNA non-specific endonuclease endA - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 GHFFDFOM_02518 220668.lp_2907 2.6e-139 392.0 COG1670@1|root,COG1670@2|Bacteria,1V3W1@1239|Firmicutes,4HH6A@91061|Bacilli,3F6G6@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain yokL3 - - - - - - - - - - - Acetyltransf_3 GHFFDFOM_02519 220668.lp_2909 3.05e-126 358.0 COG1670@1|root,COG1670@2|Bacteria,1TVME@1239|Firmicutes,4I3IH@91061|Bacilli,3F5W5@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 GHFFDFOM_02520 220668.lp_2911 8.89e-289 788.0 COG1266@1|root,COG1266@2|Bacteria,1VNA9@1239|Firmicutes,4HRMP@91061|Bacilli,3F5T9@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi GHFFDFOM_02521 220668.lp_2912 0.0 1057.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,3F3ZJ@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn GHFFDFOM_02522 220668.lp_2913 1.57e-188 523.0 COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,4HWAW@91061|Bacilli,3F3Z7@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 GHFFDFOM_02523 220668.lp_2914 0.0 1120.0 COG4907@1|root,COG4907@2|Bacteria,1TS3Q@1239|Firmicutes,4HF7D@91061|Bacilli,3F4AT@33958|Lactobacillaceae 91061|Bacilli S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 GHFFDFOM_02524 220668.lp_2915 0.0 1650.0 COG0178@1|root,COG0178@2|Bacteria,1TP0A@1239|Firmicutes,4HTKA@91061|Bacilli,3FC8R@33958|Lactobacillaceae 91061|Bacilli L excinuclease ABC uvrA3 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran GHFFDFOM_02525 220668.lp_2917 2.84e-266 732.0 COG0477@1|root,2ZBIK@2|Bacteria,1UG5D@1239|Firmicutes,4H9W5@91061|Bacilli,3FBS8@33958|Lactobacillaceae 91061|Bacilli EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 GHFFDFOM_02526 220668.lp_2918 2.78e-222 612.0 COG1396@1|root,COG1396@2|Bacteria,1VHH9@1239|Firmicutes,4HHNF@91061|Bacilli,3F4WA@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins ropB - - - - - - - - - - - HTH_3 GHFFDFOM_02527 220668.lp_2919 5.22e-229 629.0 COG2267@1|root,COG2267@2|Bacteria,1UV2B@1239|Firmicutes,4IDY4@91061|Bacilli,3F62X@33958|Lactobacillaceae 91061|Bacilli I Releases the N-terminal proline from various substrates - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 GHFFDFOM_02528 220668.lp_2920 0.0 870.0 COG0531@1|root,COG0531@2|Bacteria,1TPVA@1239|Firmicutes,4HAWC@91061|Bacilli,3F56G@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease,AA_permease_2 GHFFDFOM_02529 220668.lp_2921 4.03e-297 813.0 COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,4H9VB@91061|Bacilli,3F5D5@33958|Lactobacillaceae 91061|Bacilli S Vacuole effluxer Atg22 like yxiO - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 GHFFDFOM_02530 220668.lp_2922 0.0 884.0 COG1524@1|root,COG1524@2|Bacteria,1TRZ7@1239|Firmicutes,4HAY5@91061|Bacilli,3F4V5@33958|Lactobacillaceae 91061|Bacilli S type I phosphodiesterase nucleotide pyrophosphatase npp - - - - - - - - - - - Phosphodiest GHFFDFOM_02531 220668.lp_2923 1.65e-205 567.0 COG0657@1|root,COG0657@2|Bacteria,1TP1H@1239|Firmicutes,4HFZ9@91061|Bacilli,3F43I@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 GHFFDFOM_02532 220668.lp_2924 1.01e-167 469.0 COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli,3F5MQ@33958|Lactobacillaceae 91061|Bacilli K UTRA treR - - ko:K03486 - - - - ko00000,ko03000 - - - GntR,UTRA GHFFDFOM_02533 220668.lp_2925 0.0 993.0 2DBU6@1|root,2ZB4C@2|Bacteria,1VNWP@1239|Firmicutes,4HRN6@91061|Bacilli,3F51G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Gram_pos_anchor GHFFDFOM_02534 220668.lp_2926 2e-52 164.0 COG4892@1|root,COG4892@2|Bacteria,1V64Y@1239|Firmicutes,4HNUM@91061|Bacilli,3F812@33958|Lactobacillaceae 91061|Bacilli S Cytochrome B5 - - - - - - - - - - - - Cyt-b5 GHFFDFOM_02535 220668.lp_2927 8.68e-118 337.0 COG2190@1|root,COG2190@2|Bacteria,1U5RJ@1239|Firmicutes,4IFFQ@91061|Bacilli,3F6DI@33958|Lactobacillaceae 91061|Bacilli G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 pts21A - - ko:K02755 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1 GHFFDFOM_02536 220668.lp_2929 2.05e-279 763.0 COG2199@1|root,COG2199@2|Bacteria,1UI5F@1239|Firmicutes,4ISED@91061|Bacilli,3F4GZ@33958|Lactobacillaceae 91061|Bacilli T Diguanylate cyclase, GGDEF domain - - - - - - - - - - - - GGDEF GHFFDFOM_02537 220668.lp_2930 2.82e-163 456.0 COG2200@1|root,COG2200@2|Bacteria,1TVGQ@1239|Firmicutes,4HVXY@91061|Bacilli,3F626@33958|Lactobacillaceae 91061|Bacilli T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL GHFFDFOM_02538 220668.lp_2931 3.83e-135 382.0 COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,4HGJ9@91061|Bacilli,3F46H@33958|Lactobacillaceae 91061|Bacilli O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM GHFFDFOM_02539 220668.lp_2932 0.0 1515.0 COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,4HBIY@91061|Bacilli,3F435@33958|Lactobacillaceae 91061|Bacilli F Ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD GHFFDFOM_02540 220668.lp_2934 1.56e-108 312.0 2CIIZ@1|root,30A5S@2|Bacteria,1U68H@1239|Firmicutes,4IFZC@91061|Bacilli,3F7AW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02541 220668.lp_2935 5.97e-96 279.0 COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,4HISW@91061|Bacilli,3F6ZA@33958|Lactobacillaceae 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins def2 - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase GHFFDFOM_02542 220668.lp_2936 1.59e-243 668.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HDFE@91061|Bacilli,3FB4A@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE GHFFDFOM_02543 220668.lp_2937 2.97e-244 670.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,3F4D2@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - - - - - - - - - - Dus GHFFDFOM_02544 220668.lp_2939 3.7e-30 107.0 29PPJ@1|root,30AMQ@2|Bacteria,1U6VG@1239|Firmicutes,4IGPD@91061|Bacilli,3F8JU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02545 220668.lp_2940 1.81e-129 386.0 2DKKR@1|root,309UI@2|Bacteria,1U5R1@1239|Firmicutes,4IFF1@91061|Bacilli,3F6C4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Gram_pos_anchor GHFFDFOM_02546 220668.lp_2942 4.21e-211 583.0 COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,4HWQQ@91061|Bacilli,3F4CY@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_02547 220668.lp_2943 1.45e-312 853.0 COG0471@1|root,COG0471@2|Bacteria,1V093@1239|Firmicutes,4HQP0@91061|Bacilli,3F3VN@33958|Lactobacillaceae 91061|Bacilli P Sodium:sulfate symporter transmembrane region - - - - - - - - - - - - Na_sulph_symp GHFFDFOM_02548 220668.lp_2945 0.0 989.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,4HE3C@91061|Bacilli,3FB9Z@33958|Lactobacillaceae 91061|Bacilli H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD GHFFDFOM_02549 220668.lp_2948 0.0 931.0 COG4640@1|root,COG4640@2|Bacteria,1UYJN@1239|Firmicutes,4HF8I@91061|Bacilli,3FBEE@33958|Lactobacillaceae 91061|Bacilli S response to antibiotic tcaA - - ko:K21463 - - - - ko00000 - - - zf-ribbon_3,zinc_ribbon_2 GHFFDFOM_02550 220668.lp_2949 1.13e-183 516.0 COG4640@1|root,COG4640@2|Bacteria,1VIMB@1239|Firmicutes,4HP7R@91061|Bacilli,3F7Z9@33958|Lactobacillaceae 91061|Bacilli S zinc-ribbon domain - - - - - - - - - - - - zf-ribbon_3,zinc_ribbon_2 GHFFDFOM_02552 220668.lp_2952 3.54e-49 157.0 2DKPD@1|root,30A7H@2|Bacteria,1U6AH@1239|Firmicutes,4IG1V@91061|Bacilli,3F7FZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - EntA_Immun GHFFDFOM_02553 220668.lp_2953 2.46e-170 476.0 COG1073@1|root,COG1073@2|Bacteria,1V43W@1239|Firmicutes,4HNBU@91061|Bacilli,3F4SI@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase family - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 GHFFDFOM_02554 220668.lp_2954 4.74e-231 639.0 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HC7U@91061|Bacilli,3F4FE@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase system, EIIC - - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 GHFFDFOM_02555 220668.lp_2956 0.0 932.0 COG0657@1|root,COG0657@2|Bacteria,1USHI@1239|Firmicutes,4ISEE@91061|Bacilli,3F5U2@33958|Lactobacillaceae 91061|Bacilli I acetylesterase activity - - - - - - - - - - - - - GHFFDFOM_02556 220668.lp_2958 1.21e-298 832.0 COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,3F52Y@33958|Lactobacillaceae 91061|Bacilli M Collagen binding domain - - - - - - - - - - - - Collagen_bind GHFFDFOM_02557 220668.lp_2959 3.43e-206 571.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F423@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family yicL - - - - - - - - - - - EamA GHFFDFOM_02558 220668.lp_2960 3.03e-166 464.0 COG2755@1|root,COG2755@2|Bacteria,1UI5G@1239|Firmicutes,4ISEF@91061|Bacilli,3F652@33958|Lactobacillaceae 91061|Bacilli E lipolytic protein G-D-S-L family - - - - - - - - - - - - - GHFFDFOM_02559 220668.lp_2961 2.39e-225 620.0 COG2159@1|root,COG2159@2|Bacteria,1TRAY@1239|Firmicutes,4HFH2@91061|Bacilli,3F485@33958|Lactobacillaceae 91061|Bacilli S Amidohydrolase - - 4.1.1.52 ko:K22213 - - - - ko00000,ko01000 - - - Amidohydro_2 GHFFDFOM_02560 220668.lp_2963 1.98e-142 402.0 COG1309@1|root,COG1309@2|Bacteria,1V9XI@1239|Firmicutes,4HJ7Q@91061|Bacilli,3F77G@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator C-terminal region - - - - - - - - - - - - TetR_C_8,TetR_N GHFFDFOM_02561 220668.lp_2964 8.76e-63 192.0 COG1733@1|root,COG1733@2|Bacteria,1U6V2@1239|Firmicutes,4IGNZ@91061|Bacilli,3F8J1@33958|Lactobacillaceae 91061|Bacilli K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR GHFFDFOM_02562 1321814.HMPREF9089_01071 6.42e-65 206.0 COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,25W8J@186806|Eubacteriaceae 186801|Clostridia V COG1131 ABC-type multidrug transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_02566 220668.lp_2965 1.77e-205 569.0 COG1940@1|root,COG1940@2|Bacteria,1UZ80@1239|Firmicutes,4HD5J@91061|Bacilli,3FBD4@33958|Lactobacillaceae 91061|Bacilli GK ROK family ypbG - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK GHFFDFOM_02567 220668.lp_2966 0.0 1108.0 COG1132@1|root,COG1132@2|Bacteria,1TSY4@1239|Firmicutes,4HAJQ@91061|Bacilli,3FC4S@33958|Lactobacillaceae 91061|Bacilli V ABC transporter lmrA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 3.6.3.44 ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 M00700 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.123,3.A.1.21 - - ABC_membrane,ABC_tran GHFFDFOM_02568 60520.HR47_01940 2.14e-123 352.0 COG1846@1|root,COG1846@2|Bacteria,1VF51@1239|Firmicutes,4HM7R@91061|Bacilli,3F725@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR,MarR_2 GHFFDFOM_02569 220668.lp_2968 8.08e-154 432.0 COG0778@1|root,COG0778@2|Bacteria,1UYJU@1239|Firmicutes,4HBVQ@91061|Bacilli,3F4H1@33958|Lactobacillaceae 91061|Bacilli C Nitroreductase family ydgI3 - - - - - - - - - - - Nitroreductase GHFFDFOM_02570 220668.lp_2969 0.0 1244.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,3F44V@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system, EIIB nagE - 2.7.1.193,2.7.1.199,2.7.1.208 ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00267,M00268,M00270,M00272,M00303,M00806,M00809 R02738,R02780,R04111,R04394,R05132,R05199,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9 - iSB619.SA_RS08720 PTS_EIIA_1,PTS_EIIB,PTS_EIIC GHFFDFOM_02571 220668.lp_2972 4.21e-150 424.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,3F55Q@33958|Lactobacillaceae 91061|Bacilli S ATPases associated with a variety of cellular activities - - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran GHFFDFOM_02572 220668.lp_2973 2.48e-199 556.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,3F40J@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family WQ51_06230 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 GHFFDFOM_02573 220668.lp_2974 7.28e-218 602.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F462@33958|Lactobacillaceae 91061|Bacilli S ABC transporter XK27_00670 - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind GHFFDFOM_02574 220668.lp_2975 0.0 927.0 2BHMA@1|root,32BQ0@2|Bacteria,1U7E1@1239|Firmicutes,4IH9X@91061|Bacilli,3F9G7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02575 220668.lp_2976 1.4e-82 244.0 29QI7@1|root,30BHP@2|Bacteria,1U84Z@1239|Firmicutes,4II2F@91061|Bacilli,3FAJ6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02576 220668.lp_2977 4.54e-241 663.0 COG4072@1|root,COG4072@2|Bacteria,1V92G@1239|Firmicutes,4HIJ2@91061|Bacilli,3F407@33958|Lactobacillaceae 91061|Bacilli S Cell surface protein - - - - - - - - - - - - DUF3324,DUF916 GHFFDFOM_02577 220668.lp_2978 1.27e-137 394.0 29Q2H@1|root,30B15@2|Bacteria,1U7D3@1239|Firmicutes,4IH8P@91061|Bacilli,3F9EG@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL GHFFDFOM_02578 60520.HR47_01890 7.78e-124 355.0 COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli,3F6J3@33958|Lactobacillaceae 91061|Bacilli S Domain in cystathionine beta-synthase and other proteins. acuB - - ko:K04767 - - - - ko00000 - - - ACT,CBS GHFFDFOM_02579 220668.lp_2981 2.78e-158 444.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,3F3RP@33958|Lactobacillaceae 91061|Bacilli E ABC transporter livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran GHFFDFOM_02580 220668.lp_2982 1.28e-180 503.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,3F4IH@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid ATP-binding cassette transporter livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C GHFFDFOM_02581 220668.lp_2983 7.65e-192 536.0 COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,3F44M@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid transport system / permease component livM - - ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 GHFFDFOM_02582 220668.lp_2984 9.73e-197 546.0 COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,3F56V@33958|Lactobacillaceae 91061|Bacilli U Branched-chain amino acid transport system / permease component livH - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 GHFFDFOM_02583 220668.lp_2985 2.45e-268 736.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,3F591@33958|Lactobacillaceae 91061|Bacilli E Receptor family ligand binding region livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 GHFFDFOM_02585 220668.lp_2987 1.15e-43 142.0 29PH8@1|root,30AFD@2|Bacteria,1U6KC@1239|Firmicutes,4IGD6@91061|Bacilli,3F83D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02586 220668.lp_2988 5.67e-167 469.0 COG5549@1|root,COG5549@2|Bacteria,1V6X9@1239|Firmicutes,4HK8S@91061|Bacilli,3F6QI@33958|Lactobacillaceae 91061|Bacilli O Zinc-dependent metalloprotease zmp3 - - - - - - - - - - - Peptidase_M10 GHFFDFOM_02587 220668.lp_2989 2.88e-106 307.0 COG2246@1|root,COG2246@2|Bacteria,1U5D6@1239|Firmicutes,4IF4H@91061|Bacilli,3F5M1@33958|Lactobacillaceae 91061|Bacilli S GtrA-like protein gtcA3 - - - - - - - - - - - GtrA GHFFDFOM_02588 220668.lp_2991 4.08e-158 445.0 COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,4HH0D@91061|Bacilli,3F84P@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 GHFFDFOM_02589 220668.lp_2992 0.0 981.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp GHFFDFOM_02590 220668.lp_2993 1.18e-94 276.0 COG0589@1|root,COG0589@2|Bacteria,1V8UY@1239|Firmicutes,4HK2J@91061|Bacilli,3F6N5@33958|Lactobacillaceae 91061|Bacilli T Belongs to the universal stress protein A family usp2 - - - - - - - - - - - Usp GHFFDFOM_02591 220668.lp_2994 7.03e-62 189.0 29PCQ@1|root,30AAY@2|Bacteria,1U6EW@1239|Firmicutes,4IG6Q@91061|Bacilli,3F7RQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02592 220668.lp_2995 1.81e-150 424.0 COG0398@1|root,COG0398@2|Bacteria,1V6V7@1239|Firmicutes,4HITM@91061|Bacilli,3F417@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc GHFFDFOM_02593 60520.HR47_01805 8.58e-65 197.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,3F7DH@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, ArsR family czrA - - ko:K22043 - - - - ko00000,ko03000 - - - HTH_5 GHFFDFOM_02594 220668.lp_2998 3.21e-123 352.0 COG4300@1|root,COG4300@2|Bacteria,1VUU3@1239|Firmicutes,4HVGH@91061|Bacilli,3F6NP@33958|Lactobacillaceae 91061|Bacilli P Cadmium resistance transporter - - - - - - - - - - - - Cad GHFFDFOM_02595 220668.lp_3000 0.0 1211.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F44P@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein yhcA - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD GHFFDFOM_02596 220668.lp_3001 3.93e-38 141.0 COG1409@1|root,COG3119@1|root,COG1409@2|Bacteria,COG3119@2|Bacteria,1VTPR@1239|Firmicutes,4HJP1@91061|Bacilli,3F437@33958|Lactobacillaceae 91061|Bacilli P Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3,Phosphodiest GHFFDFOM_02597 220668.lp_3001 0.0 1682.0 COG1409@1|root,COG3119@1|root,COG1409@2|Bacteria,COG3119@2|Bacteria,1VTPR@1239|Firmicutes,4HJP1@91061|Bacilli,3F437@33958|Lactobacillaceae 91061|Bacilli P Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3,Phosphodiest GHFFDFOM_02598 220668.lp_3002 2.03e-84 248.0 29NZ7@1|root,309XC@2|Bacteria,1U5VX@1239|Firmicutes,4IFJQ@91061|Bacilli,3F6KY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02599 220668.lp_3003 1.93e-205 567.0 COG0639@1|root,COG0639@2|Bacteria,1UZK9@1239|Firmicutes,4HG1F@91061|Bacilli,3F5JR@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase superfamily domain prpA3 - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - Metallophos_2 GHFFDFOM_02600 220668.lp_3004 1.21e-73 220.0 29P97@1|root,30A7B@2|Bacteria,1U6AA@1239|Firmicutes,4IG1K@91061|Bacilli,3F7FH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02601 220668.lp_3006 4.15e-193 536.0 COG1396@1|root,COG1396@2|Bacteria,1UI5I@1239|Firmicutes,4ISEH@91061|Bacilli,3F5XX@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 GHFFDFOM_02602 220668.lp_3008 3.91e-100 290.0 COG2190@1|root,COG2190@2|Bacteria,1U5YM@1239|Firmicutes,4IFMP@91061|Bacilli,3F6QB@33958|Lactobacillaceae 91061|Bacilli G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 pts23A - - ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 - - PTS_EIIA_1 GHFFDFOM_02603 220668.lp_3009 7.47e-70 211.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,3F77Q@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit ptcB - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB GHFFDFOM_02604 220668.lp_3010 0.0 928.0 COG1455@1|root,COG1455@2|Bacteria,1VTVX@1239|Firmicutes,4HFKM@91061|Bacilli,3FC6X@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane pts23C - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC GHFFDFOM_02605 220668.lp_3011 0.0 957.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HDER@91061|Bacilli,3FC7C@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family pbg6 - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 GHFFDFOM_02606 220668.lp_3012 1.57e-237 654.0 COG0451@1|root,COG0451@2|Bacteria,1UEMD@1239|Firmicutes,4HDN7@91061|Bacilli,3F5S3@33958|Lactobacillaceae 91061|Bacilli GM Male sterility protein - - - - - - - - - - - - 3Beta_HSD,Epimerase GHFFDFOM_02607 220668.lp_3013 2.1e-99 288.0 COG0789@1|root,COG0789@2|Bacteria,1V7AK@1239|Firmicutes,4HJVT@91061|Bacilli,3F78U@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 GHFFDFOM_02608 220668.lp_3014 4.61e-101 297.0 COG1388@1|root,COG1388@2|Bacteria,1UI5H@1239|Firmicutes,4ISEG@91061|Bacilli,3F5QI@33958|Lactobacillaceae 91061|Bacilli M LysM domain - - - - - - - - - - - - LysM,SLT,Transglycosylas GHFFDFOM_02609 220668.lp_3015 5.02e-129 369.0 COG1388@1|root,COG1388@2|Bacteria,1U5IQ@1239|Firmicutes,4IF9G@91061|Bacilli,3F61M@33958|Lactobacillaceae 91061|Bacilli M Lysin motif - - - - - - - - - - - - LysM GHFFDFOM_02610 220668.lp_3016 1.4e-138 392.0 29Q4V@1|root,30B3N@2|Bacteria,1U7H5@1239|Firmicutes,4IHDP@91061|Bacilli,3F9P5@33958|Lactobacillaceae 91061|Bacilli S SdpI/YhfL protein family - - - - - - - - - - - - SdpI GHFFDFOM_02611 220668.lp_3017 1.58e-72 218.0 COG4043@1|root,COG4043@2|Bacteria,1VEJD@1239|Firmicutes,4HNU5@91061|Bacilli,3F8KY@33958|Lactobacillaceae 91061|Bacilli S ASCH nudA - - - - - - - - - - - ASCH GHFFDFOM_02612 220668.lp_3018 4.74e-211 583.0 COG0803@1|root,COG0803@2|Bacteria,1V110@1239|Firmicutes,4HZ7G@91061|Bacilli,3FBJR@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family psaA - - ko:K02077,ko:K11707 ko02010,map02010 M00244,M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA GHFFDFOM_02613 220668.lp_3019 3.57e-120 343.0 29PB8@1|root,30A9F@2|Bacteria,1U6CY@1239|Firmicutes,4IG4Q@91061|Bacilli,3F7MS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02614 220668.lp_3020 5.72e-157 439.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,3F642@33958|Lactobacillaceae 91061|Bacilli L Methyladenine glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco GHFFDFOM_02615 220668.lp_3021 6.14e-282 769.0 COG2199@1|root,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,4HBT1@91061|Bacilli,3F4R9@33958|Lactobacillaceae 91061|Bacilli T diguanylate cyclase - - - - - - - - - - - - GGDEF,Hpt,Response_reg GHFFDFOM_02616 220668.lp_3022 5.23e-97 282.0 2DMPJ@1|root,32SWG@2|Bacteria,1V7RA@1239|Firmicutes,4IG6C@91061|Bacilli,3F7QU@33958|Lactobacillaceae 91061|Bacilli S Psort location Cytoplasmic, score - - - - - - - - - - - - - GHFFDFOM_02617 220668.lp_3023 0.0 981.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HFGA@91061|Bacilli,3FCBJ@33958|Lactobacillaceae 91061|Bacilli L impB/mucB/samB family C-terminal domain umuC - - ko:K03502 - - - - ko00000,ko03400 - - - IMS,IMS_C GHFFDFOM_02618 220668.lp_3024 2.02e-215 595.0 COG0583@1|root,COG0583@2|Bacteria,1TQWY@1239|Firmicutes,4HW0R@91061|Bacilli,3F75S@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_02619 220668.lp_3025 3.05e-95 277.0 2B06A@1|root,31SH3@2|Bacteria,1U6RC@1239|Firmicutes,4IGIR@91061|Bacilli,3F8CV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02620 220668.lp_3026 5.38e-167 468.0 COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,3F3VA@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short GHFFDFOM_02621 1136177.KCA1_2481 1.54e-221 624.0 COG3069@1|root,COG3069@2|Bacteria,1UI5N@1239|Firmicutes,4ISEK@91061|Bacilli,3F5Z0@33958|Lactobacillaceae 91061|Bacilli C C4-dicarboxylate transmembrane transporter activity - - - - - - - - - - - - - GHFFDFOM_02622 220668.lp_3029 3.57e-150 422.0 COG0702@1|root,COG0702@2|Bacteria,1V7A7@1239|Firmicutes,4HIII@91061|Bacilli,3F63T@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10 GHFFDFOM_02623 220668.lp_3030 1.17e-120 343.0 COG1881@1|root,COG1881@2|Bacteria,1U5RI@1239|Firmicutes,4IFFP@91061|Bacilli,3F6DG@33958|Lactobacillaceae 91061|Bacilli S Phosphatidylethanolamine-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP GHFFDFOM_02624 220668.lp_3031 6.7e-102 294.0 COG1917@1|root,COG1917@2|Bacteria,1TRVH@1239|Firmicutes,4HGCZ@91061|Bacilli,3F6JT@33958|Lactobacillaceae 91061|Bacilli S Cupin domain yphH - - - - - - - - - - - Cupin_2 GHFFDFOM_02625 220668.lp_3032 3.55e-79 235.0 COG4925@1|root,COG4925@2|Bacteria,1VWMQ@1239|Firmicutes,4IGQ3@91061|Bacilli,3F8KM@33958|Lactobacillaceae 91061|Bacilli I sulfurtransferase activity - - - - - - - - - - - - Cyclophil_like GHFFDFOM_02626 220668.lp_3033 3.83e-178 496.0 COG1028@1|root,COG1028@2|Bacteria,1TRQC@1239|Firmicutes,4HD7P@91061|Bacilli,3F4FH@33958|Lactobacillaceae 91061|Bacilli IQ reductase gdh - 1.1.1.47,1.1.1.53 ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 - R01520,R01521,R04831,R04834,R04844,R04847 RC00066,RC00139,RC01219,RC01220 ko00000,ko00001,ko01000 - - - adh_short_C2 GHFFDFOM_02627 220668.lp_3034 3.41e-151 425.0 COG0702@1|root,COG0702@2|Bacteria,1U573@1239|Firmicutes,4IEYN@91061|Bacilli,3F503@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10 GHFFDFOM_02628 220668.lp_3038 2.31e-277 759.0 2DSXT@1|root,32UTZ@2|Bacteria,1VRBZ@1239|Firmicutes,4HT22@91061|Bacilli,3F4NM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF998 GHFFDFOM_02629 220668.lp_3040 0.0 1147.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147,ko:K18892 ko02010,map02010 M00708 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 - - ABC_membrane,ABC_tran GHFFDFOM_02630 220668.lp_3042 0.0 1075.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein XK27_09600 - - ko:K06147,ko:K18891 ko02010,map02010 M00708 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 - - ABC_membrane,ABC_tran GHFFDFOM_02631 220668.lp_3043 1.3e-226 628.0 COG5549@1|root,COG5549@2|Bacteria 2|Bacteria O protein import - - - - - - - - - - - - DUF4214,DUF4953,DUF5117,DUF5118,MACPF,Peptidase_M10,Peptidase_M43 GHFFDFOM_02632 220668.lp_3044 3.23e-290 792.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,3FC42@33958|Lactobacillaceae 91061|Bacilli E Peptidase family M20/M25/M40 amd - - - - - - - - - - - M20_dimer,Peptidase_M20 GHFFDFOM_02633 220668.lp_3045 2.43e-208 576.0 COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,4HB8Y@91061|Bacilli,3F4IT@33958|Lactobacillaceae 91061|Bacilli IQ KR domain yhxD - - - - - - - - - - - adh_short_C2 GHFFDFOM_02635 220668.lp_3047 2.3e-91 268.0 2CARX@1|root,34BQY@2|Bacteria,1VYYP@1239|Firmicutes,4HYXX@91061|Bacilli,3F7EH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Polyketide_cyc2 GHFFDFOM_02636 220668.lp_3048 5.2e-187 520.0 COG1396@1|root,COG1396@2|Bacteria,1U4VN@1239|Firmicutes,4IPPT@91061|Bacilli,3FBDK@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3 GHFFDFOM_02637 220668.lp_3049 0.0 948.0 COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,4HA0N@91061|Bacilli,3F4J0@33958|Lactobacillaceae 91061|Bacilli E Amino Acid - - - - - - - - - - - - AA_permease_2 GHFFDFOM_02638 220668.lp_3050 2.03e-87 257.0 COG1388@1|root,COG1388@2|Bacteria,1U5V5@1239|Firmicutes,4IFIT@91061|Bacilli,3F6J1@33958|Lactobacillaceae 91061|Bacilli M LysM domain lysM - - - - - - - - - - - - GHFFDFOM_02639 220668.lp_3051 1.71e-285 779.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAPA@91061|Bacilli,3F4SZ@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase dhaT - 1.1.1.202 ko:K00086 ko00561,ko00640,map00561,map00640 - R02377,R03119 RC00087 ko00000,ko00001,ko01000 - - - Fe-ADH GHFFDFOM_02640 220668.lp_3054 6.8e-272 743.0 COG1062@1|root,COG1062@2|Bacteria,1TP8E@1239|Firmicutes,4HAH9@91061|Bacilli,3F3QP@33958|Lactobacillaceae 91061|Bacilli C Zn-dependent alcohol dehydrogenases, class III adhC - 1.1.1.90 ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N GHFFDFOM_02641 220668.lp_3055 0.0 1171.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,3F4IX@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase copA - 3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54 ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5,3.A.3.6 - - E1-E2_ATPase,Hydrolase GHFFDFOM_02642 220668.lp_3057 1.23e-57 178.0 COG4633@1|root,COG4633@2|Bacteria,1W06G@1239|Firmicutes,4HZAG@91061|Bacilli,3F7FA@33958|Lactobacillaceae 91061|Bacilli S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 GHFFDFOM_02643 220668.lp_3058 1.36e-84 249.0 COG4633@1|root,COG4633@2|Bacteria,1VE0E@1239|Firmicutes,4HMFJ@91061|Bacilli,3F6KW@33958|Lactobacillaceae 91061|Bacilli S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 GHFFDFOM_02644 220668.lp_3059 0.0 2236.0 COG0810@1|root,COG0810@2|Bacteria,1UIXM@1239|Firmicutes,4ISVX@91061|Bacilli,3F5J8@33958|Lactobacillaceae 91061|Bacilli M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins aapA - - - - - - - - - - - Gram_pos_anchor,MucBP,YSIRK_signal GHFFDFOM_02645 220668.lp_3060 2.81e-181 504.0 COG4977@1|root,COG4977@2|Bacteria,1UI5R@1239|Firmicutes,4ISEM@91061|Bacilli,3F4P2@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_18 GHFFDFOM_02646 220668.lp_3062 1.47e-51 163.0 COG3743@1|root,COG3743@2|Bacteria,1VEZU@1239|Firmicutes,4HQ97@91061|Bacilli,3F8KI@33958|Lactobacillaceae 91061|Bacilli S TfoX C-terminal domain - - - ko:K07343 - - - - ko00000 - - - TfoX_C GHFFDFOM_02647 220668.lp_3063 3.05e-289 792.0 COG3290@1|root,COG3290@2|Bacteria,1W1ZJ@1239|Firmicutes,4IEYA@91061|Bacilli,3F4ZC@33958|Lactobacillaceae 91061|Bacilli T GHKL domain hpk9 - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 GHFFDFOM_02648 220668.lp_3064 0.0 902.0 2DTX9@1|root,33N2V@2|Bacteria,1UFZZ@1239|Firmicutes,4IF1S@91061|Bacilli,3F5CN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02649 220668.lp_3065 2.69e-99 288.0 29PEQ@1|root,30ACW@2|Bacteria,1U6H2@1239|Firmicutes,4IG9B@91061|Bacilli,3F7WU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02650 220668.lp_3066 4.72e-242 666.0 COG4072@1|root,COG4072@2|Bacteria,1V92G@1239|Firmicutes,4HIJ2@91061|Bacilli,3F407@33958|Lactobacillaceae 91061|Bacilli S Cell surface protein - - - - - - - - - - - - DUF3324,DUF916 GHFFDFOM_02651 60520.HR47_04215 6.02e-137 390.0 2DKIK@1|root,309KJ@2|Bacteria,1U5A5@1239|Firmicutes,4IF1M@91061|Bacilli,3F5C2@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL GHFFDFOM_02652 220668.lp_3069 4.62e-226 623.0 COG0604@1|root,COG0604@2|Bacteria,1VSE2@1239|Firmicutes,4HUTX@91061|Bacilli,3F5BT@33958|Lactobacillaceae 91061|Bacilli C Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 GHFFDFOM_02653 220668.lp_3070 1.27e-90 265.0 2F916@1|root,309SE@2|Bacteria,1U5KS@1239|Firmicutes,4IFBR@91061|Bacilli,3F65Y@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn GHFFDFOM_02654 220668.lp_3071 3.33e-149 419.0 COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,4HH7M@91061|Bacilli,3F4JW@33958|Lactobacillaceae 91061|Bacilli S GyrI-like small molecule binding domain - - - - - - - - - - - - GyrI-like GHFFDFOM_02655 220668.lp_3072 1.59e-243 669.0 COG4072@1|root,COG4072@2|Bacteria,1VCXS@1239|Firmicutes,4HKJG@91061|Bacilli,3F5HA@33958|Lactobacillaceae 91061|Bacilli S Cell surface protein ynjC - - - - - - - - - - - DUF3324,DUF916 GHFFDFOM_02656 220668.lp_3073 4.48e-130 370.0 2CH9P@1|root,309JF@2|Bacteria,1U582@1239|Firmicutes,4IEZC@91061|Bacilli,3F53T@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL GHFFDFOM_02657 220668.lp_3074 1.47e-83 246.0 29P95@1|root,30A79@2|Bacteria,1U6A8@1239|Firmicutes,4IG1G@91061|Bacilli,3F7F7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02658 220668.lp_3075 4.93e-302 864.0 COG4886@1|root,COG4886@2|Bacteria,1UYD7@1239|Firmicutes,4HHUD@91061|Bacilli,3F5NI@33958|Lactobacillaceae 91061|Bacilli NU Mycoplasma protein of unknown function, DUF285 - - - - - - - - - - - - DUF285,Gram_pos_anchor,MucBP,SLAP,WxL,YSIRK_signal GHFFDFOM_02659 220668.lp_3077 4.8e-156 442.0 29NNA@1|root,309K8@2|Bacteria,1U59G@1239|Firmicutes,4IF0U@91061|Bacilli,3F59P@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02660 220668.lp_3078 4.31e-149 420.0 COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli,3F56K@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 GHFFDFOM_02661 220668.lp_3081 3.25e-81 240.0 COG1733@1|root,COG1733@2|Bacteria,1V43K@1239|Firmicutes,4HH01@91061|Bacilli,3F6PX@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, HxlR family ytcD - - - - - - - - - - - HxlR GHFFDFOM_02662 220668.lp_3082 1.81e-272 747.0 COG0477@1|root,COG2814@2|Bacteria,1TRNU@1239|Firmicutes,4HCSX@91061|Bacilli,3FCA6@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1,Sugar_tr GHFFDFOM_02663 220668.lp_3084 4.52e-147 414.0 COG1376@1|root,COG1376@2|Bacteria,1V4KP@1239|Firmicutes,4HIBF@91061|Bacilli,3F6PH@33958|Lactobacillaceae 91061|Bacilli M ErfK YbiS YcfS YnhG - - - - - - - - - - - - YkuD GHFFDFOM_02664 220668.lp_3085 0.0 1276.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,3F3NT@33958|Lactobacillaceae 91061|Bacilli E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 GHFFDFOM_02665 220668.lp_3087 2.68e-172 481.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,3F6N8@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg GHFFDFOM_02666 220668.lp_3088 1.77e-282 774.0 COG3290@1|root,COG3290@2|Bacteria,1V1ET@1239|Firmicutes,4HGNA@91061|Bacilli,3F7J2@33958|Lactobacillaceae 91061|Bacilli T GHKL domain blpH - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 GHFFDFOM_02669 220668.lp_3090 3.75e-129 367.0 COG1309@1|root,COG1309@2|Bacteria,1U51T@1239|Firmicutes,4IETF@91061|Bacilli,3F40Q@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GHFFDFOM_02670 220668.lp_3091 3.77e-216 597.0 COG0702@1|root,COG0702@2|Bacteria,1V9EI@1239|Firmicutes,4HJCA@91061|Bacilli,3F4GJ@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10,NmrA GHFFDFOM_02671 220668.lp_3092 0.0 919.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3F47F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh GHFFDFOM_02672 220668.lp_3093 0.0 1218.0 COG3757@1|root,COG3757@2|Bacteria,1V3SH@1239|Firmicutes,4HNR1@91061|Bacilli,3F63N@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - - - - - - - - - - CW_binding_1,Glyco_hydro_25,SH3_5,SH3_8 GHFFDFOM_02673 220668.lp_3094 1.62e-62 191.0 COG4430@1|root,COG4430@2|Bacteria,1VA6D@1239|Firmicutes,4HXXX@91061|Bacilli,3F7HB@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1905) - - - - - - - - - - - - DUF1905 GHFFDFOM_02674 220668.lp_3095 1.27e-83 246.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HNAK@91061|Bacilli,3F6U8@33958|Lactobacillaceae 91061|Bacilli K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR GHFFDFOM_02675 220668.lp_3096 3.27e-170 475.0 COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4IPPS@91061|Bacilli,3FC9K@33958|Lactobacillaceae 91061|Bacilli S KR domain - - - - - - - - - - - - adh_short GHFFDFOM_02676 220668.lp_3097 4.57e-123 352.0 COG1309@1|root,COG1309@2|Bacteria,1VBRZ@1239|Firmicutes,4HXJE@91061|Bacilli,3F62W@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GHFFDFOM_02677 220668.lp_3098 4.05e-243 668.0 COG0451@1|root,COG0451@2|Bacteria,1UEMD@1239|Firmicutes,4HDN7@91061|Bacilli,3F5S3@33958|Lactobacillaceae 91061|Bacilli GM Male sterility protein - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase GHFFDFOM_02678 220668.lp_3099 1.27e-129 368.0 COG3548@1|root,COG3548@2|Bacteria,1VFW9@1239|Firmicutes,4HR1J@91061|Bacilli,3F4JD@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 GHFFDFOM_02679 220668.lp_3100 1.97e-229 631.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,3F4U1@33958|Lactobacillaceae 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red GHFFDFOM_02681 220668.lp_3101 0.0 916.0 COG0477@1|root,COG0477@2|Bacteria,1UI5Q@1239|Firmicutes,4HYNY@91061|Bacilli,3FBS9@33958|Lactobacillaceae 91061|Bacilli U Sugar (and other) transporter yfjF - - - - - - - - - - - MFS_1 GHFFDFOM_02682 220668.lp_3102 2.64e-141 399.0 COG1309@1|root,COG1309@2|Bacteria,1V2M4@1239|Firmicutes,4HMH5@91061|Bacilli,3F6MM@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_11,TetR_N GHFFDFOM_02683 220668.lp_3103 7.05e-219 604.0 COG0614@1|root,COG0614@2|Bacteria,1TQMK@1239|Firmicutes,4HBP4@91061|Bacilli,3F4YN@33958|Lactobacillaceae 91061|Bacilli P Periplasmic binding protein fhuD - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 GHFFDFOM_02684 220668.lp_3104 2.13e-186 518.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HADG@91061|Bacilli,3FC36@33958|Lactobacillaceae 91061|Bacilli HP ABC transporter fhuC - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran GHFFDFOM_02685 220668.lp_3105 1.81e-228 630.0 COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,4HA75@91061|Bacilli,3FCBQ@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fhuB - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD GHFFDFOM_02686 220668.lp_3106 3.32e-219 607.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4H9QQ@91061|Bacilli,3F4T9@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fhuG - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD GHFFDFOM_02687 220668.lp_3107 3.74e-120 343.0 COG1309@1|root,COG1309@2|Bacteria,1UV2D@1239|Firmicutes,4HZAY@91061|Bacilli,3F8X9@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GHFFDFOM_02688 220668.lp_3108 3.89e-210 581.0 COG0451@1|root,COG0451@2|Bacteria,1V0SH@1239|Firmicutes,4HPN7@91061|Bacilli 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - Epimerase GHFFDFOM_02689 1423734.JCM14202_587 1.04e-41 139.0 COG0640@1|root,COG0640@2|Bacteria,1VF0J@1239|Firmicutes,4HP0R@91061|Bacilli,3F8E3@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 GHFFDFOM_02690 1423734.JCM14202_588 1.17e-204 575.0 COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,3F4X1@33958|Lactobacillaceae 91061|Bacilli EGP transporter - - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1,Sugar_tr GHFFDFOM_02691 220668.lp_3110 2.47e-168 471.0 COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,3F468@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short GHFFDFOM_02692 220668.lp_3111 4.01e-96 281.0 COG0110@1|root,COG0110@2|Bacteria,1TSQQ@1239|Firmicutes,4HJJ7@91061|Bacilli,3F73Z@33958|Lactobacillaceae 91061|Bacilli S transferase hexapeptide repeat - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2 GHFFDFOM_02693 220668.lp_3112 4.31e-193 536.0 COG0300@1|root,COG1028@1|root,COG0300@2|Bacteria,COG1028@2|Bacteria,1TRQB@1239|Firmicutes,4HAY3@91061|Bacilli,3F3M7@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short GHFFDFOM_02694 220668.lp_3113 4.51e-84 248.0 COG0789@1|root,COG0789@2|Bacteria,1U7N9@1239|Firmicutes,4IHJI@91061|Bacilli,3F9XX@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 GHFFDFOM_02695 220668.lp_3114 0.0 1746.0 COG3266@1|root,COG3266@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - Gram_pos_anchor,MucBP GHFFDFOM_02696 220668.lp_3114 0.0 1583.0 COG3266@1|root,COG3266@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - Gram_pos_anchor,MucBP GHFFDFOM_02697 220668.lp_3115 7.08e-232 640.0 COG4072@1|root,COG4072@2|Bacteria,1U51H@1239|Firmicutes,4IET6@91061|Bacilli,3F5KF@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF916) - - - - - - - - - - - - DUF3324,DUF916 GHFFDFOM_02698 220668.lp_3116 1.1e-115 333.0 2CH9P@1|root,324R5@2|Bacteria,1UQXW@1239|Firmicutes,4IFNM@91061|Bacilli,3F6RK@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL GHFFDFOM_02699 220668.lp_3117 8.05e-267 761.0 COG4886@1|root,COG4932@1|root,COG4886@2|Bacteria,COG4932@2|Bacteria,1UYD7@1239|Firmicutes,4HHUD@91061|Bacilli,3F5NI@33958|Lactobacillaceae 91061|Bacilli NU Mycoplasma protein of unknown function, DUF285 - - - - - - - - - - - - DUF285,Gram_pos_anchor,MucBP,SLAP,WxL,YSIRK_signal GHFFDFOM_02700 220668.lp_3119 6.88e-152 427.0 COG1309@1|root,COG1309@2|Bacteria,1VG5A@1239|Firmicutes,4HP2P@91061|Bacilli,3F6MB@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GHFFDFOM_02701 220668.lp_3120 0.0 1146.0 COG0481@1|root,COG0481@2|Bacteria,1VSME@1239|Firmicutes,4HTAG@91061|Bacilli,3F4V3@33958|Lactobacillaceae 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA2 - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C GHFFDFOM_02702 220668.lp_3122 0.0 1002.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter nhaP4 - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger GHFFDFOM_02703 220668.lp_3123 4.54e-202 558.0 COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,4HKK0@91061|Bacilli,3F5W0@33958|Lactobacillaceae 91061|Bacilli L NADH pyrophosphatase zinc ribbon domain - - 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,NUDIX-like,zf-NADH-PPase GHFFDFOM_02704 220668.lp_3124 1.29e-206 572.0 COG0583@1|root,COG0583@2|Bacteria,1V1MH@1239|Firmicutes,4HFVE@91061|Bacilli,3F527@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_02705 220668.lp_3125 0.0 972.0 COG1053@1|root,COG1053@2|Bacteria,1TT1Q@1239|Firmicutes,4IPXT@91061|Bacilli,3F4DI@33958|Lactobacillaceae 91061|Bacilli C FAD binding domain - - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FMN_bind GHFFDFOM_02706 220668.lp_3127 0.0 1526.0 COG4886@1|root,COG4886@2|Bacteria,1UIXN@1239|Firmicutes,4ISVY@91061|Bacilli,3FBTR@33958|Lactobacillaceae 91061|Bacilli S MucBP domain - - - - - - - - - - - - Gram_pos_anchor,MucBP GHFFDFOM_02708 1291743.LOSG293_490020 6.66e-115 330.0 2A9SW@1|root,30Z0H@2|Bacteria,1V4IG@1239|Firmicutes,4HHW5@91061|Bacilli,3F884@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF536,HTH_11 GHFFDFOM_02709 1122149.BACN01000100_gene1977 1.22e-220 608.0 COG5527@1|root,COG5527@2|Bacteria,1V8VU@1239|Firmicutes,4HWIQ@91061|Bacilli,3F45C@33958|Lactobacillaceae 91061|Bacilli L Initiator Replication protein - - - - - - - - - - - - Rep_3 GHFFDFOM_02710 1423775.BAMN01000043_gene23 4.9e-38 127.0 2DKQ8@1|root,30AAT@2|Bacteria,1U6EN@1239|Firmicutes,4IG6F@91061|Bacilli,3F7R3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02711 1138822.PL11_10630 1.08e-138 392.0 COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4IEJ7@91061|Bacilli,3F4SP@33958|Lactobacillaceae 91061|Bacilli L Integrase - - - - - - - - - - - - Phage_integrase GHFFDFOM_02712 1122149.BACN01000100_gene1980 1.11e-59 184.0 COG2161@1|root,COG2161@2|Bacteria,1U6CD@1239|Firmicutes,4IG41@91061|Bacilli,3F7KJ@33958|Lactobacillaceae 91061|Bacilli D Antitoxin component of a toxin-antitoxin (TA) module - - - ko:K19159 - - - - ko00000,ko02048 - - - PhdYeFM_antitox GHFFDFOM_02713 46256.BBIK01000013_gene1706 1.82e-77 231.0 COG3041@1|root,COG3041@2|Bacteria 2|Bacteria S endonuclease activity yafQ GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006415,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032984,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034655,GO:0042221,GO:0042710,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043565,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044010,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044764,GO:0044877,GO:0046483,GO:0046677,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 - ko:K19157 - - - - ko00000,ko01000,ko02048 - - - YafQ_toxin GHFFDFOM_02714 387344.LVIS_A11 6.85e-178 496.0 COG1396@1|root,COG1396@2|Bacteria,1W1Q8@1239|Firmicutes,4I0U9@91061|Bacilli,3F7V4@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 GHFFDFOM_02716 60520.HR47_11205 8.03e-107 314.0 COG3250@1|root,COG3250@2|Bacteria,1TRVA@1239|Firmicutes,4HFMH@91061|Bacilli,3F51Z@33958|Lactobacillaceae 91061|Bacilli G beta-galactosidase lacM - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N GHFFDFOM_02717 1154757.Q5C_06505 1.08e-51 162.0 COG3345@1|root,COG3345@2|Bacteria 2|Bacteria G alpha-galactosidase rafA - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase GHFFDFOM_02718 1437603.BMON_1228 0.0 884.0 COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4CZZF@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - 1.16.1.1 ko:K00520,ko:K21739 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim GHFFDFOM_02719 1400520.LFAB_17310 0.0 1285.0 COG0507@1|root,COG0507@2|Bacteria,1VQWC@1239|Firmicutes,4HD6B@91061|Bacilli,3F4DP@33958|Lactobacillaceae 91061|Bacilli L MobA MobL family protein traA - - - - - - - - - - - MobA_MobL GHFFDFOM_02720 1138822.PL11_10675 4.67e-35 120.0 29P8B@1|root,30A6E@2|Bacteria,1U69C@1239|Firmicutes,4IG0H@91061|Bacilli,3F7CM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02721 1400520.LFAB_17320 6.04e-43 142.0 2EJES@1|root,33D5R@2|Bacteria,1VKZC@1239|Firmicutes,4HRGI@91061|Bacilli,3F6Y2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02722 797515.HMPREF9103_01667 4.32e-45 148.0 COG0500@1|root,COG2226@2|Bacteria,1TSAZ@1239|Firmicutes,4HIIG@91061|Bacilli,3F4S0@33958|Lactobacillaceae 91061|Bacilli Q Methyltransferase - - - - - - - - - - - - Methyltransf_11 GHFFDFOM_02723 1291743.LOSG293_220200 5.21e-92 271.0 2AC4N@1|root,311NX@2|Bacteria,1U59I@1239|Firmicutes,4IF0X@91061|Bacilli,3F59S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02725 1045004.OKIT_0534 0.0 944.0 COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,4H9ZN@91061|Bacilli 91061|Bacilli U COG3505 Type IV secretory pathway, VirD4 components traK - - ko:K03205 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T4SS-DNA_transf GHFFDFOM_02726 1045004.OKIT_0906 3.65e-193 537.0 2EN0Y@1|root,33FP4@2|Bacteria,1VPIB@1239|Firmicutes,4HRWI@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02728 203123.OEOE_0093 0.0 1031.0 COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,4AYEZ@81850|Leuconostocaceae 91061|Bacilli L C-terminal repeat of topoisomerase traI - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim,Toprim_Crpt,zf-C4_Topoisom GHFFDFOM_02729 1122149.BACN01000143_gene320 3.73e-44 143.0 29P8A@1|root,30A6D@2|Bacteria,1U69B@1239|Firmicutes,4IG0G@91061|Bacilli,3F7CJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02730 1033837.WANG_1717 5.29e-13 63.5 2DKR8@1|root,30AFV@2|Bacteria,1U6KV@1239|Firmicutes,4IGDN@91061|Bacilli,3F84D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02731 1423734.JCM14202_2807 1.98e-175 496.0 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,3F55E@33958|Lactobacillaceae 91061|Bacilli S Replication initiator protein A repA - - - - - - - - - - - RepA_N GHFFDFOM_02732 1400520.LFAB_17340 0.0 875.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease cycA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease GHFFDFOM_02733 797515.HMPREF9103_02050 4.38e-26 97.4 2BFIJ@1|root,329CF@2|Bacteria,1UPZ5@1239|Firmicutes,4IVDI@91061|Bacilli,3F8GB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02734 1400520.LFAB_17345 5.3e-49 156.0 COG0272@1|root,COG0272@2|Bacteria,1U6VR@1239|Firmicutes,4IGPT@91061|Bacilli,3F8K9@33958|Lactobacillaceae 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA - - - - - - - - - - - - BRCT GHFFDFOM_02735 220668.45723554 1.18e-184 514.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HCBZ@91061|Bacilli,3F4QA@33958|Lactobacillaceae 91061|Bacilli D CobQ CobB MinD ParA nucleotide binding domain protein soj - - - - - - - - - - - AAA_31 GHFFDFOM_02736 525318.HMPREF0497_2925 2.03e-31 114.0 29PW5@1|root,30AUG@2|Bacteria,1U74C@1239|Firmicutes,4IGYZ@91061|Bacilli,3F8YJ@33958|Lactobacillaceae 91061|Bacilli S Family of unknown function (DUF5388) - - - - - - - - - - - - DUF5388 GHFFDFOM_02737 220668.lp_0193 7.07e-102 311.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein malL - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,DUF3459,Malt_amylase_C GHFFDFOM_02738 1400520.LFAB_16990 2.17e-304 834.0 COG0471@1|root,COG0471@2|Bacteria,1TSGE@1239|Firmicutes,4HDE4@91061|Bacilli,3F4RH@33958|Lactobacillaceae 91061|Bacilli P Sodium:sulfate symporter transmembrane region - - - ko:K03319 - - - - ko00000 2.A.47 - - Na_sulph_symp GHFFDFOM_02739 1400520.LFAB_16985 0.0 1031.0 COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1UZHI@1239|Firmicutes,4I3MZ@91061|Bacilli,3F4A4@33958|Lactobacillaceae 91061|Bacilli C FMN_bind - - - - - - - - - - - - FAD_binding_2,FMN_bind GHFFDFOM_02740 1400520.LFAB_16975 3.55e-169 477.0 COG0583@1|root,COG0583@2|Bacteria,1V5VW@1239|Firmicutes,4HHDY@91061|Bacilli,3F5D2@33958|Lactobacillaceae 91061|Bacilli K LysR family - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_02741 1400520.LFAB_00905 1.61e-74 231.0 COG0583@1|root,COG0583@2|Bacteria,1V5VW@1239|Firmicutes,4HHDY@91061|Bacilli,3F5F3@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_02742 1545701.LACWKB10_1045 1.12e-29 110.0 COG0789@1|root,COG0789@2|Bacteria,1VB69@1239|Firmicutes,4HN6R@91061|Bacilli,3FC69@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 GHFFDFOM_02743 1423734.JCM14202_437 2.78e-54 173.0 COG0599@1|root,COG0599@2|Bacteria,1V78I@1239|Firmicutes,4HKFY@91061|Bacilli,3F5I2@33958|Lactobacillaceae 91061|Bacilli S Carboxymuconolactone decarboxylase family pcaC - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD GHFFDFOM_02744 1229756.C269_08560 2.65e-90 277.0 COG0583@1|root,COG0583@2|Bacteria,1TP9T@1239|Firmicutes,4HCXX@91061|Bacilli,4AWIQ@81850|Leuconostocaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_02745 1423806.JCM15457_505 2.25e-307 853.0 COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1TT1Q@1239|Firmicutes,4IPXT@91061|Bacilli,3F4DI@33958|Lactobacillaceae 91061|Bacilli C FAD binding domain - - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FMN_bind GHFFDFOM_02746 220668.lp_3129 3.07e-40 133.0 2BPRH@1|root,32IIS@2|Bacteria,1U81W@1239|Firmicutes,4IHZ9@91061|Bacilli,3FAFB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02747 1400520.LFAB_17405 1.78e-81 243.0 COG1846@1|root,COG1846@2|Bacteria,1U65M@1239|Firmicutes,4IFVG@91061|Bacilli,3F74C@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR GHFFDFOM_02748 525309.HMPREF0494_0875 0.0 1149.0 COG3203@1|root,COG4932@1|root,COG3203@2|Bacteria,COG4932@2|Bacteria,1VXP5@1239|Firmicutes,4HWZF@91061|Bacilli,3F5AT@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - DUF1542,Gram_pos_anchor,MucBP GHFFDFOM_02749 1423732.BALS01000064_gene2233 1.89e-71 216.0 29PE3@1|root,32D7A@2|Bacteria,1U7IM@1239|Firmicutes,4IHFA@91061|Bacilli,3F9RV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02750 543734.LCABL_25860 2.44e-303 830.0 COG0477@1|root,COG0477@2|Bacteria,1UJ8F@1239|Firmicutes,4IT4C@91061|Bacilli,3FBUG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_5 GHFFDFOM_02751 543734.LCABL_25870 0.0 1071.0 COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli,3F3XB@33958|Lactobacillaceae 91061|Bacilli Q Multicopper oxidase sufI - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 GHFFDFOM_02752 543734.LCABL_25880 8.86e-35 119.0 2FB4N@1|root,343B1@2|Bacteria,1VZEN@1239|Firmicutes,4HYPA@91061|Bacilli,3F944@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02753 543734.LCABL_25890 3.42e-09 55.8 COG0053@1|root,COG0053@2|Bacteria,1V9B6@1239|Firmicutes,4HJTJ@91061|Bacilli,3F4M1@33958|Lactobacillaceae 91061|Bacilli P Cation efflux family - - - - - - - - - - - - Cation_efflux GHFFDFOM_02754 1074451.CRL705_640 5.35e-65 204.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve GHFFDFOM_02755 1302286.BAOT01000076_gene2219 2.77e-145 410.0 2DKQ9@1|root,30AAV@2|Bacteria,1U6EU@1239|Firmicutes,4IG6M@91061|Bacilli,3F7RH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02756 1138822.PL11_10420 4.34e-155 443.0 COG5527@1|root,COG5527@2|Bacteria,1V8VU@1239|Firmicutes,4HWIQ@91061|Bacilli,3F45C@33958|Lactobacillaceae 91061|Bacilli L Initiator Replication protein - - - - - - - - - - - - Rep_3 GHFFDFOM_02758 1116231.SMA_p0014 2.01e-22 91.7 2E4NU@1|root,32ZHN@2|Bacteria,1VF06@1239|Firmicutes,4HPMK@91061|Bacilli 91061|Bacilli S Bacterial mobilisation protein (MobC) mobC - - - - - - - - - - - MobC GHFFDFOM_02759 1116231.SMA_p0015 2.4e-128 383.0 COG1196@1|root,COG1196@2|Bacteria,1UI9G@1239|Firmicutes,4ISNN@91061|Bacilli 91061|Bacilli D Relaxase/Mobilisation nuclease domain - - - - - - - - - - - - Relaxase GHFFDFOM_02771 220668.lp_1289 3.26e-119 341.0 COG0503@1|root,COG0503@2|Bacteria,1V1XS@1239|Firmicutes,4HG1T@91061|Bacilli,3F6EK@33958|Lactobacillaceae 91061|Bacilli F Phosphoribosyl transferase domain - - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran GHFFDFOM_02772 220668.lp_1290 1.28e-236 653.0 COG0659@1|root,COG0659@2|Bacteria,1UY33@1239|Firmicutes,4HDN5@91061|Bacilli,3F41X@33958|Lactobacillaceae 91061|Bacilli P secondary active sulfate transmembrane transporter activity - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease GHFFDFOM_02773 220668.lp_1291 1.25e-124 354.0 2CCDY@1|root,309UQ@2|Bacteria,1U5R9@1239|Firmicutes,4IFFA@91061|Bacilli,3F6CU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02774 220668.lp_1292 1.58e-122 349.0 COG0454@1|root,COG0456@2|Bacteria,1V8P4@1239|Firmicutes,4HVM8@91061|Bacilli,3F65X@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 GHFFDFOM_02775 220668.lp_1293 8.44e-200 553.0 COG0639@1|root,COG0639@2|Bacteria,1UZK9@1239|Firmicutes,4HG1F@91061|Bacilli,3F5JR@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase superfamily domain prpA3 - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - Metallophos_2 GHFFDFOM_02777 220668.lp_1295 5.39e-292 800.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp GHFFDFOM_02778 220668.lp_1296 1.78e-240 660.0 COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli,3F4VU@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase GHFFDFOM_02779 220668.lp_1297 0.0 880.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,3F4BG@33958|Lactobacillaceae 91061|Bacilli E amino acid ybgF - - ko:K02205,ko:K03293,ko:K16235,ko:K16236 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.10 - - AA_permease GHFFDFOM_02780 220668.lp_1298 7.89e-216 596.0 COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli,3F4UT@33958|Lactobacillaceae 91061|Bacilli H homocysteine S-methyltransferase mmuM - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans GHFFDFOM_02781 220668.lp_1299 0.0 1015.0 COG0438@1|root,COG2849@1|root,COG0438@2|Bacteria,COG2849@2|Bacteria,1V09I@1239|Firmicutes,4IPXN@91061|Bacilli,3FBEI@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Glycos_transf_1 GHFFDFOM_02782 220668.lp_1300 3.35e-157 442.0 2DKHQ@1|root,309HG@2|Bacteria,1U53R@1239|Firmicutes,4IEV1@91061|Bacilli,3F4DM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02783 220668.lp_1301 2.78e-273 749.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,3F3T0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N GHFFDFOM_02784 220668.lp_1302 0.0 962.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator mdr - - - - - - - - - - - MFS_1 GHFFDFOM_02785 220668.lp_1310 0.0 1095.0 COG4627@1|root,COG4627@2|Bacteria,1UIXE@1239|Firmicutes,4ISVQ@91061|Bacilli,3F5JK@33958|Lactobacillaceae 91061|Bacilli S Pfam Methyltransferase - - - - - - - - - - - - - GHFFDFOM_02786 220668.lp_1311 1.75e-185 526.0 COG0438@1|root,COG0438@2|Bacteria,1V1TS@1239|Firmicutes,4HG8T@91061|Bacilli,3FC16@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 tagE2 - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Asp1,Glycos_transf_1 GHFFDFOM_02787 220668.lp_1311 2.94e-143 415.0 COG0438@1|root,COG0438@2|Bacteria,1V1TS@1239|Firmicutes,4HG8T@91061|Bacilli,3FC16@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 tagE2 - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Asp1,Glycos_transf_1 GHFFDFOM_02788 220668.lp_1312 0.0 1019.0 COG0438@1|root,COG0438@2|Bacteria,1UZU7@1239|Firmicutes,4H9N9@91061|Bacilli,3FC17@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 tagE3 - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Glycos_transf_1 GHFFDFOM_02789 220668.lp_1313 9.32e-40 131.0 29PFH@1|root,30ADN@2|Bacteria,1U6I4@1239|Firmicutes,4IGAF@91061|Bacilli,3F7YN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02790 220668.lp_1314 3.03e-122 349.0 COG0144@1|root,COG0144@2|Bacteria,1UHQD@1239|Firmicutes,4HIMC@91061|Bacilli,3F6K1@33958|Lactobacillaceae 91061|Bacilli J Putative rRNA methylase mraW1 - - - - - - - - - - - rRNA_methylase GHFFDFOM_02791 220668.lp_1315 1.03e-160 449.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,3F5CM@33958|Lactobacillaceae 91061|Bacilli I Acid phosphatase homologues yodM - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 GHFFDFOM_02792 220668.lp_1316 0.0 1685.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,3F46M@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 GHFFDFOM_02793 220668.lp_1317 0.0 1036.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,3F404@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C GHFFDFOM_02794 220668.lp_1319 5.04e-176 490.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,3F41G@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 GHFFDFOM_02795 220668.lp_1320 5.24e-194 538.0 COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,3F480@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N GHFFDFOM_02796 220668.lp_1321 0.0 940.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,3F3UV@33958|Lactobacillaceae 91061|Bacilli E dipeptidase PepV pepV - 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 GHFFDFOM_02797 220668.lp_1322 2.16e-109 315.0 COG0589@1|root,COG0589@2|Bacteria,1VMC9@1239|Firmicutes,4HYXY@91061|Bacilli,3F6UZ@33958|Lactobacillaceae 91061|Bacilli T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp GHFFDFOM_02798 220668.lp_1324 1.02e-258 709.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HA50@91061|Bacilli,3FC3B@33958|Lactobacillaceae 91061|Bacilli E Belongs to the ABC transporter superfamily ugpC - 3.6.3.20 ko:K05816,ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.1.3 - - ABC_tran,TOBE_2 GHFFDFOM_02799 220668.lp_1325 4.39e-219 605.0 COG1175@1|root,COG1175@2|Bacteria,1TSIQ@1239|Firmicutes,4HC0D@91061|Bacilli,3FCAR@33958|Lactobacillaceae 91061|Bacilli U Binding-protein-dependent transport system inner membrane component ugpA - - ko:K02025,ko:K05814 ko02010,map02010 M00198,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 - - BPD_transp_1 GHFFDFOM_02800 220668.lp_1326 1.77e-192 535.0 COG0395@1|root,COG0395@2|Bacteria,1TR0I@1239|Firmicutes,4HB8C@91061|Bacilli,3F4Q5@33958|Lactobacillaceae 91061|Bacilli G ABC transporter permease ugpE - - ko:K05815 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - BPD_transp_1 GHFFDFOM_02801 220668.lp_1327 0.0 903.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4HARC@91061|Bacilli,3FC76@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein ugpB - - ko:K05813 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - SBP_bac_8 GHFFDFOM_02802 220668.lp_1328 5.45e-162 453.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,3F4E3@33958|Lactobacillaceae 91061|Bacilli C glycerophosphoryl diester phosphodiesterase glpQ1 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD GHFFDFOM_02803 220668.lp_1329 2.07e-155 436.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,3F4MY@33958|Lactobacillaceae 91061|Bacilli F deoxynucleoside kinase dgk2 - - - - - - - - - - - dNK GHFFDFOM_02804 220668.lp_1330 3.55e-72 218.0 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,3F6YZ@33958|Lactobacillaceae 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL GHFFDFOM_02805 220668.lp_1332 1.48e-315 904.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,3F3Y3@33958|Lactobacillaceae 91061|Bacilli V domain protein XK27_06930 - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3,DUF3533 GHFFDFOM_02807 220668.lp_1334 1.16e-160 451.0 COG0842@1|root,COG0842@2|Bacteria,1V1WK@1239|Firmicutes,4ISVR@91061|Bacilli,3F78J@33958|Lactobacillaceae 91061|Bacilli V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - GHFFDFOM_02808 220668.lp_1335 3.06e-201 557.0 COG1131@1|root,COG1131@2|Bacteria,1TRNT@1239|Firmicutes,4HB3P@91061|Bacilli,3F5U0@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_02809 220668.lp_1336 2.57e-226 624.0 COG1131@1|root,COG3279@1|root,COG1131@2|Bacteria,COG3279@2|Bacteria,1TSA4@1239|Firmicutes,4HD29@91061|Bacilli,3F6CY@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,LytTR GHFFDFOM_02811 220668.lp_1339 6.96e-198 547.0 COG0225@1|root,COG0225@2|Bacteria,1TS05@1239|Firmicutes,4HAPI@91061|Bacilli,3FC52@33958|Lactobacillaceae 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine mrsA1 - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - EntA_Immun,PMSR GHFFDFOM_02812 220668.lp_1341 5.2e-85 251.0 COG0789@1|root,COG0789@2|Bacteria,1U80Z@1239|Firmicutes,4IHYD@91061|Bacilli,3FAED@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - - GHFFDFOM_02813 220668.lp_1342 1.64e-151 426.0 COG0702@1|root,COG0702@2|Bacteria,1U7GB@1239|Firmicutes,4IHCH@91061|Bacilli,3F9M1@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10 GHFFDFOM_02814 220668.lp_1343 9.36e-205 568.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli 91061|Bacilli EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily ydeD - - - - - - - - - - - EamA GHFFDFOM_02815 220668.lp_1353 1.97e-191 531.0 COG0561@1|root,COG0561@2|Bacteria,1UYC4@1239|Firmicutes,4HGTM@91061|Bacilli,3F5R1@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 GHFFDFOM_02816 220668.lp_1354 7.83e-140 395.0 29NQX@1|root,309NV@2|Bacteria,1U5EA@1239|Firmicutes,4IF5Q@91061|Bacilli,3F5Q3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02817 220668.lp_1355 5.1e-284 778.0 COG3290@1|root,COG3290@2|Bacteria,1V1ET@1239|Firmicutes,4HGNA@91061|Bacilli,3F71I@33958|Lactobacillaceae 91061|Bacilli T GHKL domain pltK - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 GHFFDFOM_02818 220668.lp_1356 9.01e-179 498.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,3F3VI@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain agrA - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg GHFFDFOM_02819 220668.lp_1357 5.37e-74 221.0 29P6H@1|root,30A4M@2|Bacteria,1U66V@1239|Firmicutes,4IFXB@91061|Bacilli,3F77U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02820 220668.lp_1358 4.56e-78 233.0 29P15@1|root,309ZB@2|Bacteria,1U5ZB@1239|Firmicutes,4IFNC@91061|Bacilli,3F6R9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02821 220668.lp_1359 1.06e-146 414.0 COG1266@1|root,COG1266@2|Bacteria,1VFRX@1239|Firmicutes,4HRQQ@91061|Bacilli,3F4Q0@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity XK27_07085 - - ko:K07052 - - - - ko00000 - - - Abi GHFFDFOM_02822 220668.lp_1360 2.2e-111 320.0 COG1846@1|root,COG1846@2|Bacteria,1V6G0@1239|Firmicutes,4HKQR@91061|Bacilli,3F74F@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein ohrR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K18906 - M00700,M00702,M00704,M00717 - - ko00000,ko00002,ko01504,ko03000 - - - MarR GHFFDFOM_02823 220668.lp_1362 1.25e-118 339.0 29VVQ@1|root,30HDJ@2|Bacteria,1UHI8@1239|Firmicutes,4IFDH@91061|Bacilli,3F68W@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02824 220668.lp_1363 7.12e-62 189.0 2FCT0@1|root,344W0@2|Bacteria,1W0FC@1239|Firmicutes,4HXX0@91061|Bacilli,3F7QR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - YbjQ_1 GHFFDFOM_02825 220668.lp_1364 0.0 1500.0 COG0178@1|root,COG0178@2|Bacteria,1TR1H@1239|Firmicutes,4H9RE@91061|Bacilli,3F50Y@33958|Lactobacillaceae 91061|Bacilli L ABC transporter uvrA2 - - - - - - - - - - - ABC_tran GHFFDFOM_02828 220668.lp_1369 4.29e-87 257.0 29NZD@1|root,309XI@2|Bacteria,1U5W7@1239|Firmicutes,4IFJW@91061|Bacilli,3F6M7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02829 220668.lp_1370 9.03e-16 69.3 29QJD@1|root,30BIY@2|Bacteria,1U871@1239|Firmicutes,4II4R@91061|Bacilli,3FAMK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02830 220668.lp_1371 3.89e-237 653.0 2CDNX@1|root,309JA@2|Bacteria,1U57U@1239|Firmicutes,4IEZ2@91061|Bacilli,3F51R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02831 220668.lp_1372 4.91e-117 335.0 COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,4HNK7@91061|Bacilli,3F4GH@33958|Lactobacillaceae 91061|Bacilli S Teichoic acid glycosylation protein gtcA1 - - - - - - - - - - - GtrA GHFFDFOM_02832 220668.lp_1373 8.01e-77 229.0 2DKNF@1|root,30A1X@2|Bacteria,1U631@1239|Firmicutes,4IFSA@91061|Bacilli,3F6XA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1516) - - - - - - - - - - - - DUF1516 GHFFDFOM_02833 220668.lp_1374 0.0 1203.0 COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,4HAB5@91061|Bacilli 91061|Bacilli E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine yitJ - 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR,S-methyl_trans GHFFDFOM_02834 220668.lp_1375 0.0 1536.0 COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,4H9QC@91061|Bacilli,3F3VW@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 GHFFDFOM_02835 220668.lp_1377 0.0 1060.0 COG3551@1|root,COG3551@2|Bacteria,1UG61@1239|Firmicutes,4IF3M@91061|Bacilli,3F5IK@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria - - - - - - - - - - - - - GHFFDFOM_02836 220668.lp_1378 2.1e-291 794.0 COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,4HC20@91061|Bacilli,3F57K@33958|Lactobacillaceae 91061|Bacilli H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 GHFFDFOM_02837 220668.lp_1379 9.14e-146 410.0 COG0529@1|root,COG0529@2|Bacteria,1TQXK@1239|Firmicutes,4HB96@91061|Bacilli,3F51N@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of activated sulfate cysC - 2.7.1.25 ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 M00176 R00509,R04928 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase GHFFDFOM_02838 220668.lp_1380 1.79e-225 622.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,3F5VH@33958|Lactobacillaceae 91061|Bacilli S DHHA1 domain nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 GHFFDFOM_02839 220668.lp_1381 0.0 1064.0 28MBK@1|root,2ZAQ1@2|Bacteria,1TSWC@1239|Firmicutes,4HCSW@91061|Bacilli,3F50E@33958|Lactobacillaceae 91061|Bacilli M Arylsulfotransferase Ig-like domain astA - 2.8.2.22 ko:K01023 - - - - ko00000,ko01000 - - - Arylsulfotran_N,Arylsulfotrans GHFFDFOM_02840 220668.lp_1385 0.0 1079.0 COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1UI5K@1239|Firmicutes,4HC1Q@91061|Bacilli,3F5S9@33958|Lactobacillaceae 91061|Bacilli P Sodium:sulfate symporter transmembrane region - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C GHFFDFOM_02841 220668.lp_1386 5.12e-315 860.0 COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HANM@91061|Bacilli,3FC3X@33958|Lactobacillaceae 91061|Bacilli V MatE dinF - - - - - - - - - - - MatE GHFFDFOM_02842 1400520.LFAB_08900 1.79e-42 139.0 2DZ2C@1|root,34C6W@2|Bacteria,1W5PP@1239|Firmicutes,4HZIR@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02845 220668.lp_1390 3.48e-103 298.0 COG2153@1|root,COG2153@2|Bacteria,1VAJY@1239|Firmicutes,4HIH7@91061|Bacilli,3FB6K@33958|Lactobacillaceae 91061|Bacilli S Acetyltransferase (GNAT) domain yybD - - ko:K02348 - - - - ko00000 - - - Acetyltransf_10 GHFFDFOM_02846 220668.lp_1391 0.0 1106.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,3F4DE@33958|Lactobacillaceae 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d GHFFDFOM_02847 220668.lp_1392 4.64e-106 306.0 29P52@1|root,30S4B@2|Bacteria,1U62Y@1239|Firmicutes,4IFS3@91061|Bacilli,3F6X6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02848 220668.lp_1393 0.0 1241.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F56Z@33958|Lactobacillaceae 91061|Bacilli V MacB-like periplasmic core domain yhcA - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD GHFFDFOM_02849 60520.HR47_02745 6.25e-138 392.0 29P2X@1|root,30A14@2|Bacteria,1U61V@1239|Firmicutes,4IFQT@91061|Bacilli,3F6UE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02850 220668.lp_1396 0.0 1602.0 COG1221@1|root,COG3933@1|root,COG1221@2|Bacteria,COG3933@2|Bacteria,1VSHE@1239|Firmicutes,4HB6T@91061|Bacilli,3F9EV@33958|Lactobacillaceae 91061|Bacilli K PRD domain celR - - - - - - - - - - - EIIA-man,HTH_24,HTH_IclR,PRD,Sigma54_activat,TrmB GHFFDFOM_02851 220668.lp_1397 2.7e-104 301.0 2ECMT@1|root,336JS@2|Bacteria,1VEKS@1239|Firmicutes 1239|Firmicutes S Domain of unknown function (DUF3284) - - - - - - - - - - - - DUF3284 GHFFDFOM_02852 220668.lp_1398 2.37e-68 207.0 COG1447@1|root,COG1447@2|Bacteria,1V9Z6@1239|Firmicutes,4HKFE@91061|Bacilli,3F7Q7@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit lacF - 2.7.1.196,2.7.1.205,2.7.1.207 ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 - - PTS_IIA GHFFDFOM_02853 220668.lp_1399 4.9e-64 195.0 COG1440@1|root,COG1440@2|Bacteria,1TTPX@1239|Firmicutes,4IHM5@91061|Bacilli,3F9ZT@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB GHFFDFOM_02854 220668.lp_1400 1.5e-310 848.0 COG1455@1|root,COG1455@2|Bacteria,1V0MP@1239|Firmicutes,4IPPQ@91061|Bacilli,3F9KT@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane - - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC GHFFDFOM_02855 220668.lp_1401 0.0 999.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 GHFFDFOM_02856 220668.lp_1402 1.28e-263 724.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 GHFFDFOM_02857 220668.lp_1403 1.72e-148 417.0 COG1376@1|root,COG1376@2|Bacteria,1V4KP@1239|Firmicutes,4HIBF@91061|Bacilli,3F6PH@33958|Lactobacillaceae 91061|Bacilli M ErfK YbiS YcfS YnhG yciB - - - - - - - - - - - YkuD GHFFDFOM_02858 220668.lp_1406 1.65e-46 149.0 COG0236@1|root,COG0236@2|Bacteria,1U6FX@1239|Firmicutes,4IG7W@91061|Bacilli,3F7TR@33958|Lactobacillaceae 91061|Bacilli J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltC2 - 6.1.1.13 ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - PP-binding GHFFDFOM_02859 220668.lp_1407 0.0 977.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB1C@91061|Bacilli,3F5IE@33958|Lactobacillaceae 91061|Bacilli K Alanine-glyoxylate amino-transferase ydfD - - ko:K18907 - M00700,M00702 - - ko00000,ko00002,ko01504,ko03000 - - - Aminotran_1_2,GntR GHFFDFOM_02860 220668.lp_1409 3.29e-132 376.0 COG1279@1|root,COG1279@2|Bacteria,1V1Q2@1239|Firmicutes,4HFYS@91061|Bacilli,3F5RR@33958|Lactobacillaceae 91061|Bacilli S LysE type translocator argO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - ko:K06895 - - - - ko00000,ko02000 2.A.75.1 - - LysE GHFFDFOM_02861 220668.lp_1410 5.35e-269 736.0 COG0436@1|root,COG0436@2|Bacteria,1TQPD@1239|Firmicutes,4HE7P@91061|Bacilli,3F3PZ@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase arcT - - - - - - - - - - - Aminotran_1_2 GHFFDFOM_02862 220668.lp_1411 2.07e-102 296.0 COG1438@1|root,COG1438@2|Bacteria,1VA3U@1239|Firmicutes,4HPCQ@91061|Bacilli,3F65K@33958|Lactobacillaceae 91061|Bacilli K Regulates arginine biosynthesis genes argR - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C GHFFDFOM_02863 220668.lp_1412 2.01e-17 73.6 29PRK@1|root,30APT@2|Bacteria,1U6YI@1239|Firmicutes,4IGSP@91061|Bacilli,3F8QD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02864 220668.lp_1413 0.0 1370.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F49Q@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein pbp2A - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase GHFFDFOM_02865 60520.HR47_02660 9.94e-71 213.0 COG3679@1|root,COG3679@2|Bacteria,1VASS@1239|Firmicutes,4HKKC@91061|Bacilli,3F822@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0342 family yheA - - - - - - - - - - - Com_YlbF GHFFDFOM_02866 220668.lp_1416 1.49e-294 803.0 COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli,3F3PX@33958|Lactobacillaceae 91061|Bacilli L Ser Thr phosphatase family protein yhaO - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,Metallophos_2 GHFFDFOM_02867 220668.lp_1417 0.0 1532.0 COG0419@1|root,COG4717@1|root,COG0419@2|Bacteria,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,3F3PF@33958|Lactobacillaceae 91061|Bacilli L AAA domain yhaN - - - - - - - - - - - AAA_27 GHFFDFOM_02868 220668.lp_1418 1.03e-240 660.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,3F4SF@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon GHFFDFOM_02869 220668.lp_1419 5.69e-277 758.0 29Q2Y@1|root,30B1J@2|Bacteria,1U7DR@1239|Firmicutes,4IH9N@91061|Bacilli,3F9FQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02870 220668.lp_1420 1.02e-234 645.0 COG0793@1|root,COG0793@2|Bacteria,1U9Z0@1239|Firmicutes,4HRFD@91061|Bacilli,3F7HQ@33958|Lactobacillaceae 91061|Bacilli M Peptidase family S41 - - - - - - - - - - - - Peptidase_S41 GHFFDFOM_02871 220668.lp_1422 6.59e-227 625.0 COG0583@1|root,COG0583@2|Bacteria,1U35Y@1239|Firmicutes,4HCXK@91061|Bacilli,3FBI9@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_02872 220668.lp_1424 9.9e-144 405.0 COG0431@1|root,COG0431@2|Bacteria,1TT2S@1239|Firmicutes,4I3MY@91061|Bacilli,3F50W@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red GHFFDFOM_02873 220668.lp_1425 0.0 1580.0 COG0431@1|root,COG1053@1|root,COG3976@1|root,COG0431@2|Bacteria,COG1053@2|Bacteria,COG3976@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,3F53U@33958|Lactobacillaceae 91061|Bacilli C FAD binding domain - - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FMN_bind,FMN_red,Shikimate_dh_N GHFFDFOM_02874 220668.lp_1426 4.26e-127 362.0 2CG2Y@1|root,309PX@2|Bacteria,1U5GR@1239|Firmicutes,4IF7G@91061|Bacilli,3F5WC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02875 220668.lp_1427 2.76e-99 288.0 COG3613@1|root,COG3613@2|Bacteria,1VB4I@1239|Firmicutes,4IRXT@91061|Bacilli,3F663@33958|Lactobacillaceae 91061|Bacilli F Nucleoside 2-deoxyribosyltransferase - - 2.4.2.6 ko:K08728 ko00240,map00240 - R02806 RC00063 ko00000,ko00001,ko01000 - - - Nuc_deoxyrib_tr GHFFDFOM_02876 220668.lp_1430 9.45e-235 646.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,3F3X7@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 2 ykoT - - - - - - - - - - - Glycos_transf_2 GHFFDFOM_02877 220668.lp_1431 0.0 1267.0 COG1807@1|root,COG1807@2|Bacteria,1UYWB@1239|Firmicutes,4HE3A@91061|Bacilli,3FB5U@33958|Lactobacillaceae 91061|Bacilli M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 GHFFDFOM_02878 220668.lp_1433 6.95e-91 266.0 2BHDE@1|root,32BFD@2|Bacteria,1UUX4@1239|Firmicutes,4I3SI@91061|Bacilli,3FA1Z@33958|Lactobacillaceae 91061|Bacilli S NUDIX domain - - - - - - - - - - - - NUDIX GHFFDFOM_02879 220668.lp_1435 0.0 1657.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HBW6@91061|Bacilli,3F49G@33958|Lactobacillaceae 91061|Bacilli S membrane - - - - - - - - - - - - YfhO GHFFDFOM_02880 60520.HR47_04355 1.22e-217 605.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4HBNA@91061|Bacilli,3F4X5@33958|Lactobacillaceae 91061|Bacilli H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 GHFFDFOM_02881 60520.HR47_04360 7.15e-110 319.0 COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4HC7B@91061|Bacilli,3F6M0@33958|Lactobacillaceae 91061|Bacilli H Riboflavin synthase ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08950,iYO844.BSU23270 Lum_binding GHFFDFOM_02882 220668.lp_1437 5.12e-285 779.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,3F4EB@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA - 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 GHFFDFOM_02883 220668.lp_1438 1.23e-106 308.0 COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,3F70X@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08940 DMRL_synthase GHFFDFOM_02884 220668.lp_1439 5.21e-137 387.0 COG3575@1|root,COG3575@2|Bacteria,1V1YD@1239|Firmicutes,4HGK6@91061|Bacilli,3F65A@33958|Lactobacillaceae 91061|Bacilli S Nucleotidyltransferase - - - ko:K09962 - - - - ko00000 - - - NTP_transf_6 GHFFDFOM_02885 220668.lp_1440 3.96e-137 387.0 2AYWY@1|root,31R2N@2|Bacteria,1UPXG@1239|Firmicutes,4IVCM@91061|Bacilli,3F66A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02886 220668.lp_1442 3.3e-151 425.0 COG0664@1|root,COG0664@2|Bacteria,1TVBM@1239|Firmicutes,4HEJG@91061|Bacilli,3F4PI@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, cAMP Regulatory protein crp2 - - ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding GHFFDFOM_02887 220668.lp_1443 9.86e-146 410.0 COG1309@1|root,COG1309@2|Bacteria,1V2M4@1239|Firmicutes,4HMH5@91061|Bacilli,3F6MM@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_11,TetR_N GHFFDFOM_02888 220668.lp_1445 1e-306 837.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase npr - 1.11.1.1 ko:K05910 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim GHFFDFOM_02889 220668.lp_1446 0.0 1922.0 2DIQK@1|root,303XB@2|Bacteria,1TVEG@1239|Firmicutes,4HT2E@91061|Bacilli,3F8IH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - WxL GHFFDFOM_02890 220668.lp_1447 1.65e-80 239.0 29Q62@1|root,30B4Z@2|Bacteria,1U7JB@1239|Firmicutes,4IHG8@91061|Bacilli,3F9T8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02891 220668.lp_1448 1.94e-247 679.0 COG4072@1|root,COG4072@2|Bacteria,1U7CK@1239|Firmicutes,4IH80@91061|Bacilli,3F9CZ@33958|Lactobacillaceae 91061|Bacilli S Fn3-like domain - - - - - - - - - - - - DUF3324,DUF916 GHFFDFOM_02892 220668.lp_1449 2.82e-138 393.0 2F5DN@1|root,33XZI@2|Bacteria,1U57B@1239|Firmicutes,4IEYS@91061|Bacilli,3F8HS@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL GHFFDFOM_02893 220668.lp_1450 1.65e-134 384.0 29Q3B@1|root,30B20@2|Bacteria,1U7EE@1239|Firmicutes,4IHAA@91061|Bacilli,3F9GY@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL GHFFDFOM_02894 220668.lp_1452 1.09e-196 547.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,3F45W@33958|Lactobacillaceae 91061|Bacilli M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3 GHFFDFOM_02895 220668.lp_1453 6.76e-73 219.0 29P6J@1|root,30A4P@2|Bacteria,1U66Y@1239|Firmicutes,4IFXE@91061|Bacilli,3F77Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02896 220668.lp_1454 3.6e-106 306.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,3F6K5@33958|Lactobacillaceae 91061|Bacilli FG histidine triad hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT GHFFDFOM_02897 220668.lp_1455 1.1e-174 487.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,3F444@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_02898 220668.lp_1456 1.58e-282 773.0 COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,3F4HH@33958|Lactobacillaceae 91061|Bacilli U ABC transporter ecsB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB GHFFDFOM_02899 220668.lp_1457 2.08e-196 543.0 COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,3F4GU@33958|Lactobacillaceae 91061|Bacilli M Choline/ethanolamine kinase ytmP - - - - - - - - - - - APH GHFFDFOM_02900 220668.lp_1458 4.7e-156 437.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,3F3QM@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 GHFFDFOM_02901 220668.lp_1459 2.94e-71 214.0 COG5584@1|root,COG5584@2|Bacteria,1VEIQ@1239|Firmicutes,4HNS2@91061|Bacilli,3FB6P@33958|Lactobacillaceae 91061|Bacilli S Peptidase propeptide and YPEB domain ytzB - - - - - - - - - - - PepSY GHFFDFOM_02902 220668.lp_1460 1.45e-145 410.0 COG0073@1|root,COG0073@2|Bacteria,1V3R1@1239|Firmicutes,4HHBI@91061|Bacilli,3F58U@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily ytpR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind GHFFDFOM_02903 220668.lp_1461 0.0 1461.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,3F441@33958|Lactobacillaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma GHFFDFOM_02904 220668.lp_1462 0.0 875.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,3F49J@33958|Lactobacillaceae 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M GHFFDFOM_02905 220668.lp_1465 3.04e-29 104.0 29PXD@1|root,30AVR@2|Bacteria,1U75W@1239|Firmicutes,4IH0H@91061|Bacilli,3F90N@33958|Lactobacillaceae 91061|Bacilli S Virus attachment protein p12 family - - - - - - - - - - - - P12 GHFFDFOM_02906 220668.lp_1466 0.0 1278.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli,3F553@33958|Lactobacillaceae 91061|Bacilli P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - iSB619.SA_RS13395 FeoB_C,FeoB_N,Gate GHFFDFOM_02907 60520.HR47_04530 4.08e-47 150.0 COG1918@1|root,COG1918@2|Bacteria,1U69I@1239|Firmicutes,4IG0P@91061|Bacilli,3F7DB@33958|Lactobacillaceae 91061|Bacilli P FeoA domain feoA - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA GHFFDFOM_02908 220668.lp_1468 1.1e-184 514.0 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,3F3XT@33958|Lactobacillaceae 91061|Bacilli O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran GHFFDFOM_02909 60520.HR47_04540 7.08e-309 842.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,3F4BR@33958|Lactobacillaceae 91061|Bacilli O FeS assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 GHFFDFOM_02910 220668.lp_1470 4.5e-299 815.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,3F3UP@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 GHFFDFOM_02911 220668.lp_1471 2.71e-108 311.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,3F6WP@33958|Lactobacillaceae 91061|Bacilli C SUF system FeS assembly protein, NifU family nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N GHFFDFOM_02912 220668.lp_1472 0.0 936.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,3F44I@33958|Lactobacillaceae 91061|Bacilli O assembly protein SufB sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 GHFFDFOM_02913 60520.HR47_04600 4.07e-60 186.0 COG2151@1|root,COG2151@2|Bacteria,1VCAX@1239|Firmicutes,4HNBK@91061|Bacilli,3FCDE@33958|Lactobacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein - - - - - - - - - - - - FeS_assembly_P GHFFDFOM_02914 1136177.KCA1_1260 1.04e-141 407.0 COG1396@1|root,COG1396@2|Bacteria,1VDMN@1239|Firmicutes,4HDVP@91061|Bacilli,3F5A3@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix - - - ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3,TPR_12 GHFFDFOM_02915 220668.lp_1507 8.51e-155 436.0 COG0670@1|root,COG0670@2|Bacteria,1V66F@1239|Firmicutes,4IR6X@91061|Bacilli,3FBMP@33958|Lactobacillaceae 91061|Bacilli S Belongs to the BI1 family ybhL - - ko:K06890 - - - - ko00000 - - - Bax1-I GHFFDFOM_02916 220668.lp_1508 0.0 1711.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,3F3ZA@33958|Lactobacillaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A GHFFDFOM_02917 220668.lp_1509 3.19e-202 559.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,3F43E@33958|Lactobacillaceae 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS GHFFDFOM_02918 220668.lp_1510 1.11e-132 377.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,3F6WF@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08510 CoaE GHFFDFOM_02919 220668.lp_1511 1.58e-117 336.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,3F65S@33958|Lactobacillaceae 91061|Bacilli K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone GHFFDFOM_02920 220668.lp_1512 0.0 872.0 COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4H9RI@91061|Bacilli,3F5D7@33958|Lactobacillaceae 91061|Bacilli L replication initiation and membrane attachment dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 GHFFDFOM_02921 220668.lp_1513 4.97e-220 607.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,3F4JK@33958|Lactobacillaceae 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 GHFFDFOM_02922 220668.lp_1514 0.0 1296.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,3F3TC@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD GHFFDFOM_02923 220668.lp_1515 2.37e-109 315.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,3F4MS@33958|Lactobacillaceae 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N GHFFDFOM_02924 1136177.KCA1_1289 6.92e-37 124.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,3F7CQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p GHFFDFOM_02925 220668.lp_1517 6.88e-73 219.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,3F6HZ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 GHFFDFOM_02926 220668.lp_1518 2.76e-74 221.0 2C8G2@1|root,348DR@2|Bacteria,1VZDC@1239|Firmicutes,4HZ47@91061|Bacilli,3F740@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02927 220668.lp_1519 7.03e-307 836.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F44J@33958|Lactobacillaceae 91061|Bacilli L AAA C-terminal domain - - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N GHFFDFOM_02928 220668.lp_1521 6.08e-253 693.0 COG0604@1|root,COG0604@2|Bacteria,1TRNC@1239|Firmicutes,4HATC@91061|Bacilli,3F48F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily qor - 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 GHFFDFOM_02929 220668.lp_1522 4.7e-83 244.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HH0A@91061|Bacilli,3F7S1@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, HxlR family ydeP - - - - - - - - - - - HxlR GHFFDFOM_02930 220668.lp_1523 2.39e-175 489.0 COG1794@1|root,COG1794@2|Bacteria,1V34N@1239|Firmicutes,4HG8W@91061|Bacilli,3F3XZ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the aspartate glutamate racemases family racD - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race GHFFDFOM_02931 220668.lp_1524 0.0 870.0 COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,3F3RY@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase yijG - - ko:K11936 ko02026,map02026 - - - ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.2,4.D.1.1.3 GT2 - Glyco_tranf_2_3,Glycos_transf_2 GHFFDFOM_02932 220668.lp_1525 6.32e-114 326.0 2E4JE@1|root,32ZEG@2|Bacteria,1VG2N@1239|Firmicutes,4HPPN@91061|Bacilli,3F5R7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02933 220668.lp_1527 5.7e-127 360.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli,3F46V@33958|Lactobacillaceae 91061|Bacilli S HAD phosphatase, family IIIA yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase GHFFDFOM_02934 220668.lp_1528 3.81e-276 754.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,3F4JU@33958|Lactobacillaceae 91061|Bacilli S Ribosome biogenesis GTPase YqeH yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 GHFFDFOM_02935 220668.lp_1529 1.27e-66 202.0 COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli,3F7EW@33958|Lactobacillaceae 91061|Bacilli J RNA-binding protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY GHFFDFOM_02936 220668.lp_1530 4.19e-153 429.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,3F4D6@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like GHFFDFOM_02937 220668.lp_1531 1.71e-149 420.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,3F47C@33958|Lactobacillaceae 91061|Bacilli H Hydrolase, HD family yqeK - - - - - - - - - - - HD GHFFDFOM_02938 220668.lp_1532 1.06e-76 229.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,3F7QN@33958|Lactobacillaceae 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS GHFFDFOM_02939 220668.lp_1533 3.3e-180 501.0 COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,4HD2W@91061|Bacilli,3F4KM@33958|Lactobacillaceae 91061|Bacilli Q Methyltransferase yqeM - - - - - - - - - - - Methyltransf_25 GHFFDFOM_02940 220668.lp_1534 1.19e-277 759.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,3F3QC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 GHFFDFOM_02941 220668.lp_1535 2.12e-126 360.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,3F61Z@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized ACR, COG1399 ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 GHFFDFOM_02942 220668.lp_1539 7.2e-123 352.0 COG3212@1|root,COG3212@2|Bacteria,1VAET@1239|Firmicutes,4HMQ8@91061|Bacilli,3F6C2@33958|Lactobacillaceae 91061|Bacilli S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY GHFFDFOM_02943 220668.lp_1540 1.13e-225 622.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family yeaB - - - - - - - - - - - Cation_efflux,ZT_dimer GHFFDFOM_02944 220668.lp_1541 0.0 939.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,3F3S8@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 GHFFDFOM_02945 220668.lp_1543 3.12e-311 850.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3NB@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N GHFFDFOM_02946 278197.PEPE_0507 3.62e-22 88.6 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein ytgB - - - - - - - - - - - Transgly_assoc GHFFDFOM_02948 220668.lp_3546 1.97e-294 805.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HA1Q@91061|Bacilli,3F427@33958|Lactobacillaceae 91061|Bacilli G PTS system sugar-specific permease component gatC - - ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 - - EIIC-GAT GHFFDFOM_02949 220668.lp_3547 6e-60 185.0 COG3414@1|root,COG3414@2|Bacteria,1VA2P@1239|Firmicutes,4IR9V@91061|Bacilli,3FBN7@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_IIB GHFFDFOM_02950 220668.lp_3548 3.99e-106 306.0 COG1762@1|root,COG1762@2|Bacteria,1V8H9@1239|Firmicutes,4HK36@91061|Bacilli,3F4A7@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.200,2.7.1.204 ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279,M00807 R05570,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5,4.A.5.1 - - PTS_EIIA_2 GHFFDFOM_02951 1400520.LFAB_17405 1.28e-74 226.0 COG1846@1|root,COG1846@2|Bacteria,1U65M@1239|Firmicutes,4IFVG@91061|Bacilli,3F74C@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR GHFFDFOM_02952 797515.HMPREF9103_01322 0.0 1097.0 COG3158@1|root,COG3158@2|Bacteria,1TRUQ@1239|Firmicutes,4HA8Z@91061|Bacilli,3F4CU@33958|Lactobacillaceae 91061|Bacilli P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans GHFFDFOM_02953 158787.BSCA_1981 5.62e-49 164.0 COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4CZDR@85004|Bifidobacteriales 201174|Actinobacteria KT Transcriptional regulatory protein, C terminal kdpE GO:0008150,GO:0040007 - ko:K02483,ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C GHFFDFOM_02954 1114972.AUAW01000027_gene719 0.0 1272.0 COG0507@1|root,COG0507@2|Bacteria,1VQWC@1239|Firmicutes,4HD6B@91061|Bacilli,3F4DP@33958|Lactobacillaceae 91061|Bacilli L MobA MobL family protein traA - - - - - - - - - - - MobA_MobL GHFFDFOM_02955 908339.HMPREF9265_1193 2.4e-37 125.0 29P8B@1|root,30A6E@2|Bacteria,1U69C@1239|Firmicutes,4IG0H@91061|Bacilli,3F7CM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02956 525309.HMPREF0494_0003 2.96e-55 172.0 2EJES@1|root,33D5R@2|Bacteria,1VKZC@1239|Firmicutes,4HRGI@91061|Bacilli,3F6Y2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02957 748671.LCRIS_00063 1.35e-55 176.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae 91061|Bacilli S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - GHFFDFOM_02958 220668.lp_3662 0.0 1710.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli,3F3RN@33958|Lactobacillaceae 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adhE - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH GHFFDFOM_02959 1449342.JQMR01000001_gene2227 6.56e-48 157.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,27G9F@186828|Carnobacteriaceae 91061|Bacilli P ArsC family spx2 - - ko:K16509 - - - - ko00000 - - - ArsC,Glutaredoxin GHFFDFOM_02960 1400520.LFAB_17220 2.72e-135 384.0 COG1961@1|root,COG1961@2|Bacteria,1UZM8@1239|Firmicutes,4IQ67@91061|Bacilli,3FBG8@33958|Lactobacillaceae 91061|Bacilli L Resolvase, N terminal domain tnpR - - - - - - - - - - - HTH_23,HTH_7,Resolvase GHFFDFOM_02961 1074451.CRL705_1644 2.48e-52 164.0 COG2963@1|root,COG2963@2|Bacteria,1VIEV@1239|Firmicutes,4HJSC@91061|Bacilli,3F6X7@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 GHFFDFOM_02962 334390.LAF_0846 1.39e-102 302.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli,3F46G@33958|Lactobacillaceae 91061|Bacilli L Integrase core domain is18 - - - - - - - - - - - HTH_21,rve GHFFDFOM_02963 1291743.LOSG293_380080 4.4e-105 305.0 COG1961@1|root,COG1961@2|Bacteria,1V51N@1239|Firmicutes,4HDX2@91061|Bacilli,3F51V@33958|Lactobacillaceae 91061|Bacilli L Resolvase, N terminal domain tnpR1 - - - - - - - - - - - HTH_7,Resolvase GHFFDFOM_02965 220668.lp_0375 2.07e-21 87.0 2BX06@1|root,3463I@2|Bacteria,1W1B6@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - GHFFDFOM_02966 169963.lmo0142a 8.72e-24 91.7 2DPGN@1|root,331ZK@2|Bacteria,1VGGX@1239|Firmicutes,4HQCE@91061|Bacilli,26MT9@186820|Listeriaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02968 220668.lp_0275 2.69e-69 223.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp GHFFDFOM_02969 220668.lp_0276 3.3e-152 427.0 29V56@1|root,30GIU@2|Bacteria,1UG55@1239|Firmicutes,4IF3C@91061|Bacilli,3F5HR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02970 220668.lp_0277 2.92e-57 178.0 29PEH@1|root,30ACP@2|Bacteria,1U6GU@1239|Firmicutes,4IG90@91061|Bacilli,3F7W4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02971 220668.lp_0279 1.55e-55 172.0 2900D@1|root,30A4B@2|Bacteria,1U66B@1239|Firmicutes,4IFWH@91061|Bacilli,3F767@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02972 220668.lp_0280 0.0 881.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F4D4@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator ydiC - - - - - - - - - - - MFS_1 GHFFDFOM_02973 220668.lp_0281 8.98e-86 253.0 COG0789@1|root,COG0789@2|Bacteria,1U6QY@1239|Firmicutes,4IGI8@91061|Bacilli,3F8C1@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 GHFFDFOM_02974 220668.lp_0282 4.54e-316 862.0 COG0642@1|root,COG2205@2|Bacteria,1VU2I@1239|Firmicutes,4HHZT@91061|Bacilli,3F475@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase hpk2 - - - - - - - - - - - HATPase_c,HisKA GHFFDFOM_02975 220668.lp_0283 1.1e-164 461.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,3F3JF@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein, C terminal rrp2 - - - - - - - - - - - Response_reg,Trans_reg_C GHFFDFOM_02976 220668.lp_0284 2.42e-65 198.0 29P4U@1|root,30A31@2|Bacteria,1U64G@1239|Firmicutes,4IFU0@91061|Bacilli,3F70P@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02977 220668.lp_0285 2.78e-167 468.0 COG1737@1|root,COG1737@2|Bacteria,1TS9A@1239|Firmicutes,4HCBF@91061|Bacilli,3F6D3@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family yidA - - - - - - - - - - - HTH_6,SIS GHFFDFOM_02978 220668.lp_0286 6.86e-311 848.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F3Q4@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane licC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - iYO844.BSU38390 PTS_EIIC GHFFDFOM_02979 220668.lp_0287 3.35e-75 224.0 29P89@1|root,30A6C@2|Bacteria,1U699@1239|Firmicutes,4IG0E@91061|Bacilli,3F7CE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02980 220668.lp_0289 2.87e-56 174.0 29PF7@1|root,30ADC@2|Bacteria,1U6HR@1239|Firmicutes,4IGA2@91061|Bacilli,3F7Y0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02981 220668.lp_0290 1.76e-236 651.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr GHFFDFOM_02982 220668.lp_0291 0.0 896.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,3F4AD@33958|Lactobacillaceae 91061|Bacilli C FAD linked oxidases, C-terminal domain loxD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 GHFFDFOM_02983 220668.lp_0292 1.49e-63 194.0 29P6D@1|root,30A4H@2|Bacteria,1U66J@1239|Firmicutes,4IFWU@91061|Bacilli,3F76U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02984 220668.lp_0293 2.04e-158 444.0 COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,4HBE0@91061|Bacilli,3FBJN@33958|Lactobacillaceae 91061|Bacilli S RelA SpoT domain protein ywaC GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951,ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT GHFFDFOM_02985 220668.lp_0294 1.17e-135 384.0 COG1309@1|root,COG1309@2|Bacteria,1VI1M@1239|Firmicutes,4HPZV@91061|Bacilli,3F530@33958|Lactobacillaceae 91061|Bacilli K transcriptional regulator - - - - - - - - - - - - TetR_C_8,TetR_N GHFFDFOM_02986 220668.lp_0295 0.0 1437.0 COG1511@1|root,COG2409@1|root,COG1511@2|Bacteria,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4HBM6@91061|Bacilli,3FCCY@33958|Lactobacillaceae 91061|Bacilli S MMPL family ydgH - - ko:K06994 - - - - ko00000 - - - MMPL GHFFDFOM_02987 220668.lp_0296 8.31e-139 391.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,3F5KA@33958|Lactobacillaceae 91061|Bacilli L glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco GHFFDFOM_02988 220668.lp_0297 0.0 1363.0 COG4886@1|root,COG4886@2|Bacteria,1U5IM@1239|Firmicutes,4IF9E@91061|Bacilli,3F61G@33958|Lactobacillaceae 91061|Bacilli S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - GHFFDFOM_02989 220668.lp_0298 3.42e-293 808.0 COG0577@1|root,COG0577@2|Bacteria,1TPSE@1239|Firmicutes,4HDMR@91061|Bacilli,3FC8Y@33958|Lactobacillaceae 91061|Bacilli V MacB-like periplasmic core domain vex3 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX GHFFDFOM_02990 220668.lp_0299 4.87e-156 437.0 COG1136@1|root,COG1136@2|Bacteria,1TP5M@1239|Firmicutes,4HBJW@91061|Bacilli,3F57B@33958|Lactobacillaceae 91061|Bacilli V ABC transporter vex2 - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_02991 220668.lp_0300 1.13e-171 480.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi GHFFDFOM_02992 220668.lp_0301 5.54e-156 439.0 COG1266@1|root,COG1266@2|Bacteria,1U62B@1239|Firmicutes,4IFRB@91061|Bacilli,3F6V5@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi GHFFDFOM_02993 220668.lp_0302 7.98e-80 248.0 COG1388@1|root,COG1388@2|Bacteria,1U5F6@1239|Firmicutes,4IF6Q@91061|Bacilli,3F5TV@33958|Lactobacillaceae 91061|Bacilli M Lysin motif - - - - - - - - - - - - LysM GHFFDFOM_02994 220668.lp_0304 2.31e-95 283.0 COG1388@1|root,COG1388@2|Bacteria,1V773@1239|Firmicutes,4HIJG@91061|Bacilli,3F3JQ@33958|Lactobacillaceae 91061|Bacilli M LysM domain protein - - - - - - - - - - - - LysM,SLAP GHFFDFOM_02995 220668.lp_0305 4.2e-88 258.0 COG0509@1|root,COG0509@2|Bacteria,1U670@1239|Firmicutes,4IFXJ@91061|Bacilli,3F784@33958|Lactobacillaceae 91061|Bacilli E Glycine cleavage H-protein gcsH1 - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H GHFFDFOM_02996 220668.lp_0306 6.1e-227 624.0 28MN3@1|root,2ZAXQ@2|Bacteria,1US2T@1239|Firmicutes,4HW4H@91061|Bacilli,3F55K@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02997 220668.lp_0307 2.8e-169 473.0 2EEPZ@1|root,338HP@2|Bacteria,1VJZJ@1239|Firmicutes,4HR6K@91061|Bacilli,3F55G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_02998 220668.lp_0308 0.0 1566.0 COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,3F473@33958|Lactobacillaceae 91061|Bacilli KL DEAD_2 uvrB3 - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1 GHFFDFOM_02999 220668.lp_0309 3.01e-75 225.0 29P4E@1|root,30A2M@2|Bacteria,1U63U@1239|Firmicutes,4IFTA@91061|Bacilli,3F6Z3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03000 220668.lp_0310 1.3e-284 778.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase GHFFDFOM_03001 220668.lp_0311 7.61e-102 295.0 COG2153@1|root,COG2153@2|Bacteria,1VAJY@1239|Firmicutes,4HIH7@91061|Bacilli,3F5B8@33958|Lactobacillaceae 91061|Bacilli S GNAT family - - - ko:K02348 - - - - ko00000 - - - Acetyltransf_10 GHFFDFOM_03002 220668.lp_0312 1.24e-99 288.0 COG1846@1|root,COG1846@2|Bacteria,1V3PS@1239|Firmicutes,4HFN6@91061|Bacilli,3F6VT@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - MarR,MarR_2 GHFFDFOM_03003 220668.lp_0313 3.91e-287 784.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,3F4N1@33958|Lactobacillaceae 91061|Bacilli C NADH dehydrogenase yumB GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iYO844.BSU32100 Pyr_redox_2 GHFFDFOM_03004 220668.lp_0314 6.01e-51 162.0 29C9K@1|root,2ZZ83@2|Bacteria,1U6R1@1239|Firmicutes,4IGIB@91061|Bacilli,3F8C8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03006 1423754.BALY01000009_gene73 1.04e-35 130.0 29UVW@1|root,30G8B@2|Bacteria,1UFFJ@1239|Firmicutes,4IEQ7@91061|Bacilli,3F7VN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_3 GHFFDFOM_03007 1423754.BALY01000009_gene72 9.25e-32 117.0 COG1952@1|root,COG1952@2|Bacteria,1U778@1239|Firmicutes,4IH20@91061|Bacilli,3F929@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase subunit SecB - - - - - - - - - - - - SecB GHFFDFOM_03008 220668.lp_0315 1.52e-264 723.0 COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,4HAET@91061|Bacilli,3F3W1@33958|Lactobacillaceae 91061|Bacilli P ABC transporter potD - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iSB619.SA_RS05395 SBP_bac_8 GHFFDFOM_03009 220668.lp_0316 1.31e-179 501.0 COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli,3F3ZN@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease potC - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 GHFFDFOM_03010 220668.lp_0317 3.14e-190 529.0 COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,4HAYS@91061|Bacilli,3F4CM@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease potB - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 GHFFDFOM_03011 220668.lp_0318 5.94e-262 717.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli,3F40H@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 - iSB619.SA_RS05380 ABC_tran,TOBE_2 GHFFDFOM_03012 220668.lp_0319 3.68e-125 356.0 COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,4HGGY@91061|Bacilli,3F5FE@33958|Lactobacillaceae 91061|Bacilli K Cupin domain - - - - - - - - - - - - Cupin_2,HTH_3 GHFFDFOM_03013 220668.lp_0320 8.08e-110 315.0 COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli,3F7EV@33958|Lactobacillaceae 91061|Bacilli S ASCH - - - - - - - - - - - - ASCH GHFFDFOM_03014 220668.lp_0321 1.88e-111 320.0 COG0454@1|root,COG0456@2|Bacteria,1V6S5@1239|Firmicutes,4HJJY@91061|Bacilli,3F6HM@33958|Lactobacillaceae 91061|Bacilli K GNAT family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 GHFFDFOM_03015 220668.lp_0322 3.52e-81 243.0 COG0454@1|root,COG0456@2|Bacteria,1UIXA@1239|Firmicutes,4ISVN@91061|Bacilli,3F70D@33958|Lactobacillaceae 91061|Bacilli K acetyltransferase - - - - - - - - - - - - Acetyltransf_10 GHFFDFOM_03016 220668.lp_0324 2.06e-30 107.0 29PNG@1|root,30AKP@2|Bacteria,1U6TW@1239|Firmicutes,4IGMQ@91061|Bacilli,3F8HB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03017 220668.lp_0325 5.05e-79 234.0 COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4I3PG@91061|Bacilli,3F70C@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - ko:K07979 - - - - ko00000,ko03000 - - - GntR GHFFDFOM_03018 220668.lp_0326 1.85e-208 577.0 COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,4HA3P@91061|Bacilli,3FC3A@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01990,ko:K16921 ko02010,map02010 M00254,M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_tran GHFFDFOM_03019 220668.lp_0327 1.08e-243 669.0 29NSX@1|root,309QZ@2|Bacteria,1U5IP@1239|Firmicutes,4IF9F@91061|Bacilli,3F61I@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - ABC2_membrane_5 GHFFDFOM_03020 220668.lp_0329 0.0 891.0 COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,4IS6J@91061|Bacilli,3F5S5@33958|Lactobacillaceae 91061|Bacilli C Aldehyde dehydrogenase family acdH - 1.1.1.1,1.2.1.10,1.2.1.87 ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927,R09097 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh GHFFDFOM_03021 60520.HR47_00655 1.16e-206 571.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,3F4EF@33958|Lactobacillaceae 91061|Bacilli G Fructose-1,6-bisphosphate aldolase, class II fba - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase GHFFDFOM_03023 220668.lp_0331 1.36e-304 832.0 COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HBAI@91061|Bacilli,3F3UZ@33958|Lactobacillaceae 91061|Bacilli G MFS/sugar transport protein xylP1 - - - - - - - - - - - MFS_2 GHFFDFOM_03024 220668.lp_0332 1.43e-170 481.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli,3F4HV@33958|Lactobacillaceae 91061|Bacilli O prohibitin homologues hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 GHFFDFOM_03025 220668.lp_0333 7.28e-42 137.0 2DKQN@1|root,30ACH@2|Bacteria,1U6GJ@1239|Firmicutes,4IG8R@91061|Bacilli,3F7VP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03026 220668.lp_0334 0.0 969.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD2 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 GHFFDFOM_03027 220668.lp_0335 6.4e-54 168.0 2930D@1|root,3270J@2|Bacteria,1USWD@1239|Firmicutes,4IG6X@91061|Bacilli,3F7S4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03028 220668.lp_0336 1.54e-123 353.0 COG1268@1|root,COG1268@2|Bacteria,1VAAD@1239|Firmicutes,4HI8T@91061|Bacilli,3F6YG@33958|Lactobacillaceae 91061|Bacilli S BioY family bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY GHFFDFOM_03029 220668.lp_0337 1.49e-227 627.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,3F5HY@33958|Lactobacillaceae 91061|Bacilli H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 GHFFDFOM_03030 220668.lp_0338 1.45e-79 235.0 COG4357@1|root,COG4357@2|Bacteria,1VB64@1239|Firmicutes,4HMGX@91061|Bacilli,3F8FS@33958|Lactobacillaceae 91061|Bacilli S CHY zinc finger - - - - - - - - - - - - zf-CHY GHFFDFOM_03031 1423807.BACO01000036_gene1053 1.06e-143 411.0 COG1464@1|root,COG1464@2|Bacteria,1TRXS@1239|Firmicutes,4HAD4@91061|Bacilli,3F5TS@33958|Lactobacillaceae 91061|Bacilli P NLPA lipoprotein metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 GHFFDFOM_03032 1423734.JCM14202_2368 7.98e-158 452.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,3F3U5@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL GHFFDFOM_03033 1423807.BACO01000036_gene1055 5.18e-115 334.0 COG2011@1|root,COG2011@2|Bacteria,1TSJS@1239|Firmicutes,4HAZD@91061|Bacilli,3F9MD@33958|Lactobacillaceae 91061|Bacilli U Binding-protein-dependent transport system inner membrane component metP_2 - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 GHFFDFOM_03034 525318.HMPREF0497_1669 5.67e-187 525.0 COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,4HB4T@91061|Bacilli,3F455@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid ykpB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C GHFFDFOM_03035 220668.lp_0339 2.07e-282 771.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,3F4TW@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase mtnE - - ko:K08969 ko00270,ko01100,map00270,map01100 M00034 R07396 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GHFFDFOM_03036 220668.lp_0340 5.25e-279 763.0 2CC2J@1|root,309K5@2|Bacteria,1U598@1239|Firmicutes,4IF0I@91061|Bacilli,3F58S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03037 220668.lp_0343 8.13e-199 550.0 COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,4HB9R@91061|Bacilli,3F4FP@33958|Lactobacillaceae 91061|Bacilli U Transport permease protein tagG GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0033036,GO:0051179,GO:0051234,GO:0071702,GO:1901264 - ko:K09692 ko02010,map02010 M00251 - - ko00000,ko00001,ko00002,ko02000 3.A.1.104 - - ABC2_membrane GHFFDFOM_03038 220668.lp_0344 9.42e-258 707.0 COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,4HC6N@91061|Bacilli,3F4V6@33958|Lactobacillaceae 91061|Bacilli GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system tagH GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0015921,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1901264,GO:1901505 3.6.3.40 ko:K09693 ko02010,map02010 M00251 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.104 - - ABC_tran,LysM GHFFDFOM_03039 220668.lp_0346 3.93e-59 182.0 29P8S@1|root,30A6W@2|Bacteria,1U69T@1239|Firmicutes,4IG0Y@91061|Bacilli,3F7E4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03040 220668.lp_0347 2.39e-121 347.0 COG1695@1|root,COG1695@2|Bacteria,1VEN3@1239|Firmicutes,4HS7A@91061|Bacilli,3F6IE@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR GHFFDFOM_03041 220668.lp_0348 0.0 897.0 COG0477@1|root,COG2211@1|root,COG0477@2|Bacteria,COG2211@2|Bacteria,1UNMW@1239|Firmicutes,4ISTJ@91061|Bacilli,3FBTN@33958|Lactobacillaceae 91061|Bacilli P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr GHFFDFOM_03042 220668.lp_0349 1.05e-308 842.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,3F3X1@33958|Lactobacillaceae 91061|Bacilli P ammonium transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp GHFFDFOM_03043 220668.lp_0350 1.49e-225 622.0 COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli,3F4M2@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily hicD1 - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N GHFFDFOM_03044 220668.lp_0351 8.95e-60 184.0 2A5G1@1|root,30U62@2|Bacteria,1U6B9@1239|Firmicutes,4IG2T@91061|Bacilli,3F7HZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03045 220668.lp_0353 2.03e-130 370.0 COG5549@1|root,COG5549@2|Bacteria,1UGZG@1239|Firmicutes,4IF9R@91061|Bacilli,3F627@33958|Lactobacillaceae 91061|Bacilli O Zinc-dependent metalloprotease zmp1 - - - - - - - - - - - Peptidase_M10 GHFFDFOM_03046 220668.lp_0354 1.14e-151 427.0 COG0120@1|root,COG0120@2|Bacteria,1V22S@1239|Firmicutes,4HFWX@91061|Bacilli,3FC6F@33958|Lactobacillaceae 91061|Bacilli G Ribose 5-phosphate isomerase A (phosphoriboisomerase A) rpiA2 - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A GHFFDFOM_03047 220668.lp_0355 0.0 1056.0 COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli,3F3XB@33958|Lactobacillaceae 91061|Bacilli Q Multicopper oxidase sufI - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 GHFFDFOM_03048 220668.lp_0357 1.08e-71 216.0 COG3759@1|root,COG3759@2|Bacteria,1VAVU@1239|Firmicutes,4HQHN@91061|Bacilli,3F7NA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1304) - - - ko:K08987 - - - - ko00000 - - - DUF1304 GHFFDFOM_03049 220668.lp_0358 1.31e-124 354.0 COG1881@1|root,COG1881@2|Bacteria,1VJEE@1239|Firmicutes,4HXTJ@91061|Bacilli,3F75J@33958|Lactobacillaceae 91061|Bacilli S Phosphatidylethanolamine-binding protein yxkA - - ko:K06910 - - - - ko00000 - - - PBP GHFFDFOM_03050 220668.lp_0359 1.61e-294 803.0 COG1419@1|root,COG3410@1|root,COG1419@2|Bacteria,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,4HBI0@91061|Bacilli,3F47M@33958|Lactobacillaceae 91061|Bacilli N Uncharacterized conserved protein (DUF2075) - - - ko:K09384 - - - - ko00000 - - - DUF2075,GIY-YIG GHFFDFOM_03051 220668.lp_0360 8.37e-108 310.0 COG1959@1|root,COG1959@2|Bacteria,1U353@1239|Firmicutes,4ICW0@91061|Bacilli,3F58B@33958|Lactobacillaceae 91061|Bacilli K Winged helix-turn-helix transcription repressor, HrcA DNA-binding - - - - - - - - - - - - Rrf2 GHFFDFOM_03052 220668.lp_0361 2.16e-103 299.0 29P3G@1|root,30A1P@2|Bacteria,1U62U@1239|Firmicutes,4IFRZ@91061|Bacilli,3F6WC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03053 220668.lp_0362 2.43e-103 302.0 COG0511@1|root,COG0511@2|Bacteria,1TWUA@1239|Firmicutes,4I5NI@91061|Bacilli,3F5YZ@33958|Lactobacillaceae 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB3 - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl GHFFDFOM_03054 220668.lp_0363 3.66e-224 617.0 COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,4HB17@91061|Bacilli,3F4T0@33958|Lactobacillaceae 91061|Bacilli F Nucleoside rihA - 3.2.2.1 ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro GHFFDFOM_03055 220668.lp_0364 1.07e-208 577.0 COG0300@1|root,COG0300@2|Bacteria,1UHN7@1239|Firmicutes,4IS46@91061|Bacilli,3F5A5@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family yneD - - - - - - - - - - - adh_short GHFFDFOM_03056 220668.lp_0365 0.0 1239.0 2E9P4@1|root,333VI@2|Bacteria,1VJPB@1239|Firmicutes,4HQ3S@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03057 203120.LEUM_1016 7.02e-103 297.0 COG0328@1|root,COG0328@2|Bacteria,1VS3E@1239|Firmicutes,4HTM4@91061|Bacilli,4AXMZ@81850|Leuconostocaceae 91061|Bacilli L RNA-DNA hybrid ribonuclease activity - - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - - GHFFDFOM_03058 220668.lp_0367 0.0 957.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HBDR@91061|Bacilli,3F44S@33958|Lactobacillaceae 91061|Bacilli EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) proWX - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC GHFFDFOM_03059 220668.lp_0368 1.1e-229 632.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,3F55H@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein proV - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran GHFFDFOM_03060 1229758.C270_07966 0.0 876.0 COG1249@1|root,COG1249@2|Bacteria,1TS0Z@1239|Firmicutes,4HBYB@91061|Bacilli,4AWJF@81850|Leuconostocaceae 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase gshR - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim GHFFDFOM_03061 220668.lp_0370 0.0 1029.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,3F3WI@33958|Lactobacillaceae 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N GHFFDFOM_03062 220668.lp_0371 0.0 1192.0 COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,3F5BS@33958|Lactobacillaceae 91061|Bacilli C C-terminal domain of alpha-glycerophosphate oxidase glpD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 - R00846,R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C GHFFDFOM_03063 220668.lp_0372 2.5e-173 483.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,3F4J6@33958|Lactobacillaceae 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP GHFFDFOM_03064 220668.lp_0373 0.0 1853.0 COG4932@1|root,COG4932@2|Bacteria,1UV28@1239|Firmicutes,4HWU5@91061|Bacilli,3F7MP@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - MucBP GHFFDFOM_03065 220668.lp_0374 5.94e-78 266.0 COG1091@1|root,COG1091@2|Bacteria 2|Bacteria M dTDP-4-dehydrorhamnose reductase activity - - - - - - - - - - - - Epimerase,RmlD_sub_bind GHFFDFOM_03067 1027396.LMOSA_10470 7.35e-50 160.0 2AWWP@1|root,31NU7@2|Bacteria,1V8BM@1239|Firmicutes,4HXUN@91061|Bacilli,26N48@186820|Listeriaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03068 220668.lp_0388 1.65e-88 260.0 2E8X6@1|root,33378@2|Bacteria,1VQHD@1239|Firmicutes 1239|Firmicutes S Immunity protein 63 - - - - - - - - - - - - Imm63 GHFFDFOM_03069 1449336.JQLO01000001_gene1243 1.93e-59 185.0 2FIIN@1|root,34AAP@2|Bacteria,1VZY1@1239|Firmicutes,4HY44@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03070 220668.lp_0391 8.5e-55 171.0 29QHX@1|root,30B9Q@2|Bacteria,1U7SF@1239|Firmicutes,4IHPT@91061|Bacilli,3FA3Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03071 220668.lp_0379 1.82e-228 628.0 2BF1Z@1|root,328TX@2|Bacteria,1UUT4@1239|Firmicutes,4IHH1@91061|Bacilli,3F9UD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03072 1158612.I580_02656 1.24e-11 62.0 2DRKH@1|root,33C67@2|Bacteria,1VMQB@1239|Firmicutes,4HSI9@91061|Bacilli 91061|Bacilli S Immunity protein 22 - - - - - - - - - - - - DUF4284 GHFFDFOM_03073 220668.lp_0381 5.89e-131 371.0 COG0666@1|root,COG0666@2|Bacteria,1VBGD@1239|Firmicutes,4HKQW@91061|Bacilli 91061|Bacilli S ankyrin repeats - - - - - - - - - - - - Ank_4 GHFFDFOM_03074 220668.lp_0382 3.31e-52 164.0 29QHX@1|root,30BHD@2|Bacteria,1U84J@1239|Firmicutes,4II20@91061|Bacilli,3FAIP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03075 220668.lp_0377 8.53e-28 102.0 29QHX@1|root,30B9Q@2|Bacteria,1U7SF@1239|Firmicutes,4IHPT@91061|Bacilli,3FA3Y@33958|Lactobacillaceae 220668.lp_0377|- - - - - - - - - - - - - - - - GHFFDFOM_03076 220668.lp_0384 2.25e-63 193.0 COG5444@1|root,COG5444@2|Bacteria,1VF7A@1239|Firmicutes,4HMKS@91061|Bacilli 91061|Bacilli U nuclease activity - - - - - - - - - - - - LXG GHFFDFOM_03077 220668.lp_0385 5.89e-90 263.0 2EG2D@1|root,339UD@2|Bacteria,1VQEB@1239|Firmicutes,4HXG9@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03078 220668.lp_0376 7.62e-29 104.0 29QHX@1|root,30BHD@2|Bacteria,1U84J@1239|Firmicutes,4II20@91061|Bacilli,3FAIP@33958|Lactobacillaceae 220668.lp_0376|- - - - - - - - - - - - - - - - GHFFDFOM_03079 1133569.AHYZ01000019_gene563 1.93e-125 361.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HBHG@91061|Bacilli,3F59Y@33958|Lactobacillaceae 91061|Bacilli L PFAM Integrase catalytic region - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,rve,rve_2 GHFFDFOM_03080 1133569.AHYZ01000019_gene564 3.5e-79 239.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity Z012_00440 - - ko:K07483 - - - - ko00000 - - - HTH_28,HTH_Tnp_1 GHFFDFOM_03081 1302286.BAOT01000074_gene2195 4.09e-88 261.0 COG3293@1|root,COG3293@2|Bacteria,1U67N@1239|Firmicutes,4IFY7@91061|Bacilli,3F79E@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_2 GHFFDFOM_03082 220668.lp_0216 4.13e-65 213.0 COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,3F4M8@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - ko:K07487 - - - - ko00000 - - - DDE_Tnp_1,DUF772 GHFFDFOM_03083 1074451.CRL705_640 5.35e-65 204.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve GHFFDFOM_03084 387344.LVIS_1797 1.41e-163 459.0 COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HI9A@91061|Bacilli,3FB69@33958|Lactobacillaceae 91061|Bacilli P integral membrane protein, YkoY family - - - - - - - - - - - - TerC GHFFDFOM_03085 1423734.JCM14202_2807 8.54e-141 405.0 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,3F55E@33958|Lactobacillaceae 91061|Bacilli S Replication initiator protein A repA - - - - - - - - - - - RepA_N GHFFDFOM_03086 334390.LAF_1214 9.66e-291 794.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,3FB4C@33958|Lactobacillaceae 91061|Bacilli L MULE transposase domain - - - - - - - - - - - - Transposase_mut GHFFDFOM_03088 314315.LCA_0141 3.14e-225 620.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli,3FB5W@33958|Lactobacillaceae 91061|Bacilli L Integrase core domain - - - ko:K07482 - - - - ko00000 - - - rve GHFFDFOM_03090 220668.lp_1166 7.62e-97 282.0 29NS2@1|root,309Q2@2|Bacteria,1U5GY@1239|Firmicutes,4IF7R@91061|Bacilli,3F5XC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03091 220668.lp_1168 2.9e-139 392.0 2BPPE@1|root,32IGN@2|Bacteria,1UG8R@1239|Firmicutes,4IF4N@91061|Bacilli,3F5MF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03092 220668.lp_1169 0.0 878.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,3F4DS@33958|Lactobacillaceae 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N GHFFDFOM_03093 220668.lp_1171 6.92e-281 768.0 COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,3F3QN@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpX - - - - - - - - - - - Beta-lactamase,SLH GHFFDFOM_03094 220668.lp_1173 4.75e-267 731.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli,3F3KQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 GHFFDFOM_03095 220668.lp_1174 7.42e-202 561.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,3F4TC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0761 family rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB GHFFDFOM_03096 220668.lp_1175 3.98e-169 472.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,3F42H@33958|Lactobacillaceae 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP GHFFDFOM_03097 220668.lp_1176 1.67e-274 750.0 COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,4HB5F@91061|Bacilli,3F52G@33958|Lactobacillaceae 91061|Bacilli M UDP-galactopyranose mutase glf - 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - - GLF,NAD_binding_8 GHFFDFOM_03098 1400520.LFAB_05195 1.38e-66 204.0 COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,4HNK7@91061|Bacilli,3F4GH@33958|Lactobacillaceae 91061|Bacilli S Teichoic acid glycosylation protein gtcA - - - - - - - - - - - GtrA GHFFDFOM_03099 1400520.LFAB_05200 0.0 1042.0 28HDP@1|root,2Z7Q8@2|Bacteria,1V01A@1239|Firmicutes,4HUBR@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03100 1400520.LFAB_05205 1.27e-144 421.0 29PZP@1|root,30AY4@2|Bacteria,1U796@1239|Firmicutes,4IH42@91061|Bacilli,3F956@33958|Lactobacillaceae 91061|Bacilli - - cps3D - - - - - - - - - - - - GHFFDFOM_03101 1536770.R50345_04525 4.51e-05 51.2 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,26SWR@186822|Paenibacillaceae 91061|Bacilli M biosynthesis protein ywqC - - - - - - - - - - - Wzz GHFFDFOM_03102 1400520.LFAB_05215 1.36e-218 612.0 2DN9M@1|root,32W9S@2|Bacteria,1VDRM@1239|Firmicutes,4HRQ0@91061|Bacilli,3F6CA@33958|Lactobacillaceae 91061|Bacilli - - cps3F - - - - - - - - - - - - GHFFDFOM_03103 1400520.LFAB_05220 1.12e-172 485.0 COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,4HFX7@91061|Bacilli 91061|Bacilli S Glycosyltransferase like family 2 - - - ko:K12992 ko02025,map02025 - - - ko00000,ko00001,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 GHFFDFOM_03104 1400520.LFAB_05225 8.11e-105 312.0 COG1216@1|root,COG1216@2|Bacteria,1V7WM@1239|Firmicutes,4HWEX@91061|Bacilli,3F7T8@33958|Lactobacillaceae 91061|Bacilli S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 GHFFDFOM_03105 1400520.LFAB_05230 9.68e-118 342.0 COG1216@1|root,COG1216@2|Bacteria,1V3IY@1239|Firmicutes,4HVIA@91061|Bacilli,3F6KK@33958|Lactobacillaceae 91061|Bacilli S Glycosyltransferase like family 2 welB - - - - - - - - - - - Glycos_transf_2 GHFFDFOM_03106 1400520.LFAB_05235 1.27e-165 470.0 COG0463@1|root,COG0463@2|Bacteria,1V2EP@1239|Firmicutes,4HHPV@91061|Bacilli,3F74Y@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 2 - - - ko:K12997 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 GHFFDFOM_03107 1400520.LFAB_05240 1.95e-189 528.0 COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli,3F4F8@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase GHFFDFOM_03108 1400520.LFAB_05245 1.27e-152 434.0 COG1216@1|root,COG1216@2|Bacteria,1V4NS@1239|Firmicutes,4HHDW@91061|Bacilli,3F6P7@33958|Lactobacillaceae 91061|Bacilli S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 GHFFDFOM_03109 1400520.LFAB_05250 5.39e-174 495.0 COG1621@1|root,COG1621@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 32 family - - 3.2.1.26,3.2.1.65 ko:K01193,ko:K01212 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R05624,R06088,R11311 RC00028,RC00077,RC03278 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32N,Glyco_hydro_43 GHFFDFOM_03110 1400520.LFAB_05260 1.87e-202 563.0 COG0463@1|root,COG0463@2|Bacteria,1UI8D@1239|Firmicutes,4IST0@91061|Bacilli,3F49C@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 GHFFDFOM_03111 1400520.LFAB_05265 8.59e-286 787.0 COG2244@1|root,COG2244@2|Bacteria,1TP7R@1239|Firmicutes,4HC84@91061|Bacilli,3F48Q@33958|Lactobacillaceae 91061|Bacilli S Membrane protein involved in the export of O-antigen and teichoic acid - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C GHFFDFOM_03112 220668.lp_1188 1.08e-137 389.0 COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,4HFQB@91061|Bacilli,3F4FN@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom GHFFDFOM_03113 220668.lp_1189 3.29e-261 714.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,3F3R6@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd GHFFDFOM_03114 220668.lp_1190 1.46e-201 558.0 COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,3F4QS@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind GHFFDFOM_03115 220668.lp_1196 5.1e-132 375.0 COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4IEJ7@91061|Bacilli,3F4SP@33958|Lactobacillaceae 91061|Bacilli L Integrase - - - - - - - - - - - - Phage_integrase GHFFDFOM_03116 220668.lp_1197 3.91e-169 474.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,3F4M5@33958|Lactobacillaceae 91061|Bacilli M biosynthesis protein epsB - - - - - - - - - - - GNVR,Wzz GHFFDFOM_03117 220668.lp_1198 8.26e-164 459.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,3F4BM@33958|Lactobacillaceae 91061|Bacilli D Capsular exopolysaccharide family ywqD - - - - - - - - - - - AAA_31,ParA GHFFDFOM_03118 220668.lp_1199 1.49e-178 498.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli,3F3RT@33958|Lactobacillaceae 91061|Bacilli GM PHP domain protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - GHFFDFOM_03119 220668.lp_1200 5.19e-224 617.0 COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli,3F5GY@33958|Lactobacillaceae 91061|Bacilli M RmlD substrate binding domain cps2D - 5.1.3.2,5.1.3.25 ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 M00361,M00362,M00632 R00291,R02984,R10279 RC00289 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS00780 Epimerase,GDP_Man_Dehyd GHFFDFOM_03120 220668.lp_1201 5.9e-160 448.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HB15@91061|Bacilli,3F5WM@33958|Lactobacillaceae 91061|Bacilli M Bacterial sugar transferase tuaA - - - - - - - - - - - Bac_transf,CoA_binding_3 GHFFDFOM_03121 980584.AFPB01000160_gene2068 6.41e-59 194.0 COG0463@1|root,COG0463@2|Bacteria,4NK1T@976|Bacteroidetes,1HZ1Q@117743|Flavobacteriia,40773@61432|unclassified Flavobacteriaceae 976|Bacteroidetes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 GHFFDFOM_03122 1136177.KCA1_0988 1.62e-191 537.0 COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,4HGEP@91061|Bacilli,3F683@33958|Lactobacillaceae 91061|Bacilli M Stealth protein CR2, conserved region 2 - - - - - - - - - - - - Stealth_CR1,Stealth_CR2 GHFFDFOM_03124 1136177.KCA1_0990 9.38e-161 460.0 COG0438@1|root,COG0438@2|Bacteria,1UHSF@1239|Firmicutes,4HB04@91061|Bacilli,3F428@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - ko:K02840 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 GHFFDFOM_03125 1136177.KCA1_0991 1.72e-166 473.0 COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,4HGEP@91061|Bacilli,3F683@33958|Lactobacillaceae 91061|Bacilli M Stealth protein CR2, conserved region 2 cps2G - - - - - - - - - - - Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4 GHFFDFOM_03126 1136177.KCA1_0992 2.27e-304 838.0 COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,4HCW6@91061|Bacilli,3F5CI@33958|Lactobacillaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score cps2I - - - - - - - - - - - Polysacc_synt GHFFDFOM_03127 1136177.KCA1_0993 8.7e-116 348.0 COG3274@1|root,COG3274@2|Bacteria,1V9EN@1239|Firmicutes,4IGF0@91061|Bacilli,3F8DD@33958|Lactobacillaceae 91061|Bacilli S Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 GHFFDFOM_03128 1136177.KCA1_0995 1.37e-26 98.6 COG3077@1|root,COG3077@2|Bacteria 2|Bacteria L bacterial-type proximal promoter sequence-specific DNA binding cps2K - - ko:K07473 - - - - ko00000,ko02048 - - - RelB GHFFDFOM_03129 1136177.KCA1_0996 1.41e-169 479.0 COG1216@1|root,COG1216@2|Bacteria,1V2KI@1239|Firmicutes,4IPXM@91061|Bacilli,3FBEH@33958|Lactobacillaceae 91061|Bacilli S Glycosyltransferase like family 2 cps3A - - ko:K07011 - - - - ko00000 - - - Glycos_transf_2 GHFFDFOM_03130 220668.lp_1216 4.65e-229 630.0 COG1216@1|root,COG1216@2|Bacteria,1V2KI@1239|Firmicutes,4IPXM@91061|Bacilli,3FBEH@33958|Lactobacillaceae 91061|Bacilli S Glycosyltransferase like family 2 cps3B - - ko:K07011 - - - - ko00000 - - - Glycos_transf_2 GHFFDFOM_03131 220668.lp_1219 2.81e-282 770.0 COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,4HB5F@91061|Bacilli,3F52G@33958|Lactobacillaceae 91061|Bacilli M UDP-galactopyranose mutase glf - 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - - GLF,NAD_binding_8 GHFFDFOM_03132 220668.lp_1220 3.93e-260 713.0 29PZP@1|root,30AY4@2|Bacteria,1U796@1239|Firmicutes,4IH42@91061|Bacilli,3F956@33958|Lactobacillaceae 91061|Bacilli - - cps3D - - - - - - - - - - - - GHFFDFOM_03133 220668.lp_1221 6.87e-144 406.0 29Q0I@1|root,30AZ0@2|Bacteria,1U7AC@1239|Firmicutes,4IH5A@91061|Bacilli,3F979@33958|Lactobacillaceae 91061|Bacilli - - cps3E - - - - - - - - - - - - GHFFDFOM_03134 1136177.KCA1_1001 2.88e-208 585.0 2DN9M@1|root,32W9S@2|Bacteria,1VDRM@1239|Firmicutes,4HRQ0@91061|Bacilli,3F6CA@33958|Lactobacillaceae 91061|Bacilli - - cps3F - - - - - - - - - - - - GHFFDFOM_03135 220668.lp_1225 3.17e-259 711.0 29Q29@1|root,30B0V@2|Bacteria,1U7CU@1239|Firmicutes,4IH8D@91061|Bacilli,3F9DU@33958|Lactobacillaceae 91061|Bacilli - - cps3H - - - - - - - - - - - - GHFFDFOM_03136 220668.lp_1226 3.82e-255 700.0 COG3594@1|root,COG3594@2|Bacteria,1V858@1239|Firmicutes,4HJH5@91061|Bacilli,3F6SS@33958|Lactobacillaceae 91061|Bacilli G Acyltransferase family cps3I - - - - - - - - - - - Acyl_transf_3 GHFFDFOM_03137 220668.lp_1227 2.94e-190 527.0 COG1442@1|root,COG1442@2|Bacteria,1U6EG@1239|Firmicutes,4HG4F@91061|Bacilli,3F539@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF4422) cps3J - - - - - - - - - - - DUF4422 GHFFDFOM_03138 220668.lp_1228 6.86e-175 488.0 COG2207@1|root,COG2207@2|Bacteria,1UIXD@1239|Firmicutes,4ISVP@91061|Bacilli,3FBTP@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 GHFFDFOM_03139 220668.lp_1229 0.0 1571.0 COG3203@1|root,COG4932@1|root,COG3203@2|Bacteria,COG4932@2|Bacteria,1VXP5@1239|Firmicutes,4HWZF@91061|Bacilli,3F5AT@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - DUF1542,Gram_pos_anchor,MucBP GHFFDFOM_03140 220668.lp_1230 2.18e-96 281.0 COG1846@1|root,COG1846@2|Bacteria,1U65M@1239|Firmicutes,4IFVG@91061|Bacilli,3F74C@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR GHFFDFOM_03141 220668.lp_1231 0.0 895.0 COG2244@1|root,COG2244@2|Bacteria,1TP7R@1239|Firmicutes,4HC84@91061|Bacilli,3F48Q@33958|Lactobacillaceae 91061|Bacilli S Membrane protein involved in the export of O-antigen and teichoic acid cps1C - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C GHFFDFOM_03142 220668.lp_1233 1.38e-155 437.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HCBG@91061|Bacilli,3F51J@33958|Lactobacillaceae 91061|Bacilli M Bacterial sugar transferase rfbP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K13012,ko:K19428 - - - - ko00000,ko01000,ko01005 - - - Bac_transf,CoA_binding_3 GHFFDFOM_03143 220668.lp_1234 9.02e-70 210.0 2CB5C@1|root,309Y8@2|Bacteria,1U5XG@1239|Firmicutes,4IFKU@91061|Bacilli,3F6NB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03144 220668.lp_1235 1.04e-45 147.0 2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF2922) - - - - - - - - - - - - DUF2922 GHFFDFOM_03145 220668.lp_1236 1.95e-41 136.0 2CB5D@1|root,30A9Q@2|Bacteria,1U6DC@1239|Firmicutes,4IG53@91061|Bacilli,3F7ND@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03146 220668.lp_1237 1.35e-34 118.0 29QQX@1|root,30BQQ@2|Bacteria,1U8HB@1239|Firmicutes,4IIF6@91061|Bacilli,3FAZG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03147 220668.lp_1238 6.87e-131 371.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - - - - - - - - - - GerE,HTH_23,Sigma70_r2,Sigma70_r4 GHFFDFOM_03148 220668.lp_1239 1.9e-168 471.0 2DKK6@1|root,309S9@2|Bacteria,1U5KM@1239|Firmicutes,4IFBJ@91061|Bacilli,3F65N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - ComK GHFFDFOM_03149 220668.lp_1240 1.01e-181 506.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,3F4BY@33958|Lactobacillaceae 91061|Bacilli S Regulatory protein RecX recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX GHFFDFOM_03150 220668.lp_1241 6.62e-138 389.0 COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli,3F48S@33958|Lactobacillaceae 91061|Bacilli J Belongs to the UPF0374 family ygaC - - ko:K07586 - - - - ko00000 - - - DUF402 GHFFDFOM_03151 220668.lp_1242 9.26e-171 478.0 COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HH84@91061|Bacilli,3F5SU@33958|Lactobacillaceae 91061|Bacilli M NlpC/P60 family lytE - - - - - - - - - - - LysM,NLPC_P60,SH3_3 GHFFDFOM_03152 1400520.LFAB_05505 3.97e-64 197.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_19,HTH_3,HTH_31 GHFFDFOM_03153 220668.lp_1244 7.17e-39 129.0 29FID@1|root,302G1@2|Bacteria,1U6EJ@1239|Firmicutes,4IG6A@91061|Bacilli,3F7QP@33958|Lactobacillaceae 91061|Bacilli S Antitoxin component of a toxin-antitoxin (TA) module - - - - - - - - - - - - PhdYeFM_antitox GHFFDFOM_03154 1136177.KCA1_1020 2.24e-166 513.0 COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,3F3QN@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpX - - - - - - - - - - - Beta-lactamase,SLH GHFFDFOM_03155 220668.lp_1245 4.22e-215 594.0 COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli,3F4M2@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily hdhL - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N GHFFDFOM_03156 220668.lp_1247 1.13e-257 709.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,3F418@33958|Lactobacillaceae 91061|Bacilli S AI-2E family transporter yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport GHFFDFOM_03157 220668.lp_1248 6.04e-94 273.0 COG0615@1|root,COG0615@2|Bacteria,1V3KY@1239|Firmicutes,4HGWZ@91061|Bacilli,3F65R@33958|Lactobacillaceae 91061|Bacilli IM Glycerol-3-phosphate cytidylyltransferase tagD - 2.7.7.39 ko:K00980 ko00564,map00564 - R00856 RC00002 ko00000,ko00001,ko01000 - - - CTP_transf_like GHFFDFOM_03158 220668.lp_1249 7.89e-290 795.0 COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,3F3V0@33958|Lactobacillaceae 91061|Bacilli EG Gluconate gntP - - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease GHFFDFOM_03159 220668.lp_1250 0.0 1013.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,3F4R2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the FGGY kinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N GHFFDFOM_03160 220668.lp_1251 1.22e-218 602.0 COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,3F4X7@33958|Lactobacillaceae 91061|Bacilli G Dehydrogenase gntZ - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 GHFFDFOM_03161 220668.lp_1253 0.0 880.0 COG1249@1|root,COG1249@2|Bacteria,1TS0Z@1239|Firmicutes,4HBYB@91061|Bacilli,3F3K2@33958|Lactobacillaceae 91061|Bacilli C Glutathione reductase gshR3 - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim GHFFDFOM_03162 220668.lp_1255 0.0 1049.0 COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli,3F489@33958|Lactobacillaceae 91061|Bacilli J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C GHFFDFOM_03163 220668.lp_1256 0.0 942.0 2FCGI@1|root,344JZ@2|Bacteria,1W0CD@1239|Firmicutes,4HYAJ@91061|Bacilli,3FB90@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03164 220668.lp_1257 3.51e-251 688.0 COG4932@1|root,COG4932@2|Bacteria,1UHY3@1239|Firmicutes,4ISAI@91061|Bacilli,3FBRZ@33958|Lactobacillaceae 91061|Bacilli M MucBP domain - - - - - - - - - - - - MucBP GHFFDFOM_03165 220668.lp_1258 1.36e-208 577.0 COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes,4HBNZ@91061|Bacilli,3F4XG@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain lysR5 - - - - - - - - - - - HTH_1,LysR_substrate GHFFDFOM_03166 60520.HR47_01000 1.01e-172 485.0 COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,4HESP@91061|Bacilli,3F3T9@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE GHFFDFOM_03167 220668.lp_1260 3.85e-76 228.0 COG4272@1|root,COG4272@2|Bacteria,1VAPQ@1239|Firmicutes,4IRG9@91061|Bacilli,3FBP6@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1634) ywjH - - - - - - - - - - - DUF1634 GHFFDFOM_03168 220668.lp_1261 0.0 1071.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GHFFDFOM_03169 220668.lp_1262 3.44e-210 582.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,3F42T@33958|Lactobacillaceae 91061|Bacilli P ABC-type dipeptide oligopeptide nickel transport systems, permease components oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 GHFFDFOM_03170 220668.lp_1263 3.59e-241 663.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,3F3W3@33958|Lactobacillaceae 91061|Bacilli EP ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N GHFFDFOM_03171 220668.lp_1264 4.86e-258 707.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,3F41T@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY GHFFDFOM_03172 220668.lp_1265 5.67e-231 635.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,3F4GM@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppF - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY GHFFDFOM_03173 220668.lp_1267 3.4e-85 251.0 COG1846@1|root,COG1846@2|Bacteria,1U5ZS@1239|Firmicutes,4IFNS@91061|Bacilli,3F6RV@33958|Lactobacillaceae 91061|Bacilli K Winged helix DNA-binding domain - - - - - - - - - - - - MarR GHFFDFOM_03174 220668.lp_1268 4.15e-131 372.0 COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4IEJ7@91061|Bacilli,3F4SP@33958|Lactobacillaceae 91061|Bacilli L Integrase - - - - - - - - - - - - Phage_integrase GHFFDFOM_03175 220668.lp_1269 0.0 1293.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,3F3K9@33958|Lactobacillaceae 91061|Bacilli O Belongs to the ClpA ClpB family clpE - - ko:K03697 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR GHFFDFOM_03176 60520.HR47_00950 5.6e-41 134.0 2EI19@1|root,33BSS@2|Bacteria,1U4CC@1239|Firmicutes,4IGST@91061|Bacilli,3F8QK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03177 1136177.KCA1_1042 1.24e-52 166.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,3F6XQ@33958|Lactobacillaceae 91061|Bacilli G phosphocarrier protein HPR ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr GHFFDFOM_03178 220668.lp_1274 0.0 1105.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,3F3MS@33958|Lactobacillaceae 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C GHFFDFOM_03179 220668.lp_1275 1.41e-285 780.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli,3F4H5@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein pimB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 GHFFDFOM_03180 220668.lp_1276 2.04e-254 696.0 COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HB9F@91061|Bacilli,3F47X@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 2.4.1.208 ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 - R05164,R10865 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 GHFFDFOM_03181 220668.lp_1277 4.36e-241 664.0 COG0392@1|root,COG0392@2|Bacteria,1UY7Z@1239|Firmicutes,4HCG6@91061|Bacilli,3F3UR@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM GHFFDFOM_03182 220668.lp_1278 6.56e-292 797.0 COG1686@1|root,COG1686@2|Bacteria,1UFQ0@1239|Firmicutes,4IEW0@91061|Bacilli,3F4NV@33958|Lactobacillaceae 91061|Bacilli M Belongs to the peptidase S11 family dacA2 - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S11 GHFFDFOM_03183 220668.lp_1280 1.66e-290 792.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase araT - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GHFFDFOM_03184 220668.lp_1281 1.56e-46 149.0 COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli,3F82V@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1797) ykuJ - - - - - - - - - - - DUF1797 GHFFDFOM_03185 220668.lp_1283 0.0 1349.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase GHFFDFOM_03186 1302286.BAOT01000074_gene2195 4.09e-88 261.0 COG3293@1|root,COG3293@2|Bacteria,1U67N@1239|Firmicutes,4IFY7@91061|Bacilli,3F79E@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_2 GHFFDFOM_03187 1122149.BACN01000133_gene193 5.93e-37 124.0 2DKQ6@1|root,30AAQ@2|Bacteria,1U6EI@1239|Firmicutes,4IG69@91061|Bacilli,3F7QK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03188 525309.HMPREF0494_0004 5.29e-49 164.0 COG4185@1|root,COG4185@2|Bacteria,1V4U7@1239|Firmicutes,4HHGF@91061|Bacilli,3F5H8@33958|Lactobacillaceae 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Zeta_toxin GHFFDFOM_03189 1133569.AHYZ01000027_gene987 4.41e-59 182.0 COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,4HGEM@91061|Bacilli,3F6VR@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase IS200-family protein - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp GHFFDFOM_03190 60520.HR47_10915 1.22e-70 218.0 COG1349@1|root,COG1349@2|Bacteria,1UXYW@1239|Firmicutes,4IQMP@91061|Bacilli,3F68Z@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - ko:K02444 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR GHFFDFOM_03191 1138822.PL11_10200 1.26e-79 236.0 COG0526@1|root,COG0526@2|Bacteria,1U5XH@1239|Firmicutes,4IFKV@91061|Bacilli,3F6NC@33958|Lactobacillaceae 91061|Bacilli CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - Thioredoxin GHFFDFOM_03192 220668.lp_0413 1.22e-36 123.0 29QDU@1|root,30BD4@2|Bacteria,1U7XW@1239|Firmicutes,4IHV9@91061|Bacilli,3FAB1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03193 220668.lp_0415 1.9e-25 94.4 2BT43@1|root,32N8N@2|Bacteria,1U8CY@1239|Firmicutes,4IIAX@91061|Bacilli,3FAUJ@33958|Lactobacillaceae 91061|Bacilli - - plnA - - - - - - - - - - - - GHFFDFOM_03194 60520.HR47_08955 3.92e-290 795.0 COG3290@1|root,COG3290@2|Bacteria,1V1ET@1239|Firmicutes,4HGNA@91061|Bacilli,3F71I@33958|Lactobacillaceae 91061|Bacilli T GHKL domain plnB - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 GHFFDFOM_03195 60520.HR47_08950 6.82e-170 475.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,3F5PZ@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain sppR - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg GHFFDFOM_03196 220668.lp_0418 1.18e-170 477.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,3F52U@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain plnD - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg GHFFDFOM_03197 220668.lp_0419 3.87e-165 464.0 COG1266@1|root,COG1266@2|Bacteria,1W74B@1239|Firmicutes,4IH2Z@91061|Bacilli,3F93M@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi GHFFDFOM_03198 220668.lp_0421 1.93e-31 109.0 29QER@1|root,30BE3@2|Bacteria,1U7ZG@1239|Firmicutes,4IHWW@91061|Bacilli,3FACU@33958|Lactobacillaceae 91061|Bacilli - - plnF - - - - - - - - - - - - GHFFDFOM_03199 220668.lp_0422 8.82e-32 110.0 2BIA2@1|root,32CFN@2|Bacteria,1U7YI@1239|Firmicutes,4IHVW@91061|Bacilli,3FABR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03200 220668.lp_0423 0.0 1347.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli,3F3QF@33958|Lactobacillaceae 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 - - - ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.112.1,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 GHFFDFOM_03201 220668.lp_0424 2.88e-307 840.0 COG0845@1|root,COG0845@2|Bacteria,1V5C8@1239|Firmicutes,4HHKB@91061|Bacilli,3F5W4@33958|Lactobacillaceae 91061|Bacilli M Transport protein ComB mesE - - ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko02000 3.A.1.112,8.A.1,8.A.1.4.2 - - HlyD_3 GHFFDFOM_03202 60520.HR47_08915 3.17e-141 401.0 COG1266@1|root,COG1266@2|Bacteria,1U7E2@1239|Firmicutes,4IH9Y@91061|Bacilli,3F9G8@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi GHFFDFOM_03203 220668.lp_0426 3.4e-153 431.0 COG1266@1|root,COG1266@2|Bacteria,1W74A@1239|Firmicutes,4IFVR@91061|Bacilli,3F750@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity plnU - - ko:K07052 - - - - ko00000 - - - Abi GHFFDFOM_03204 220668.lp_0428 2.75e-145 411.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi GHFFDFOM_03205 220668.lp_0429 7.78e-126 360.0 COG1266@1|root,COG1266@2|Bacteria,1U6ES@1239|Firmicutes,4IG6J@91061|Bacilli,3F7RC@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi GHFFDFOM_03206 60520.HR47_08895 5.5e-42 137.0 29PWX@1|root,30AV8@2|Bacteria,1U75A@1239|Firmicutes,4IGZZ@91061|Bacilli,3F8ZZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03207 220668.lp_0432 0.0 1465.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,3F486@33958|Lactobacillaceae 91061|Bacilli L DNA helicase - - - - - - - - - - - - AAA_19,UvrD_C_2 GHFFDFOM_03208 220668.lp_0433 3.54e-182 507.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,3F4ND@33958|Lactobacillaceae 91061|Bacilli S Carbon-nitrogen hydrolase mtnU - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase GHFFDFOM_03209 220668.lp_0434 8.19e-244 669.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,3F3V6@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b GHFFDFOM_03210 220668.lp_0435 2.69e-166 465.0 COG2188@1|root,COG2188@2|Bacteria,1TTCD@1239|Firmicutes,4HEXQ@91061|Bacilli,3F4DA@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein - - - - - - - - - - - - GntR,UTRA GHFFDFOM_03211 220668.lp_0436 0.0 883.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F4VG@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane chbC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC GHFFDFOM_03212 60520.HR47_08865 9.68e-34 116.0 29QG9@1|root,30BFQ@2|Bacteria,1U81V@1239|Firmicutes,4IHZ8@91061|Bacilli,3FAF9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03213 220668.lp_0438 3.55e-99 287.0 2DQNY@1|root,337UX@2|Bacteria,1VEZ0@1239|Firmicutes,4HPE2@91061|Bacilli,3F69F@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF3284) - - - - - - - - - - - - DUF3284 GHFFDFOM_03214 220668.lp_0439 0.0 868.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F4VG@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane celB - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC GHFFDFOM_03215 220668.lp_0440 0.0 1013.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 GHFFDFOM_03216 220668.lp_0441 6.97e-209 578.0 COG1940@1|root,COG1940@2|Bacteria,1V20R@1239|Firmicutes,4HFXJ@91061|Bacilli,3F60F@33958|Lactobacillaceae 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK GHFFDFOM_03217 220668.lp_0442 9.75e-175 487.0 COG1737@1|root,COG1737@2|Bacteria,1V5JY@1239|Firmicutes,4HI0D@91061|Bacilli,3FC4E@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family yecA - - - - - - - - - - - HTH_6,SIS GHFFDFOM_03218 220668.lp_0443 3.43e-243 669.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,3F4D2@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - - - - - - - - - - Dus GHFFDFOM_03219 220668.lp_0444 4.28e-263 723.0 29Q7M@1|root,30B6N@2|Bacteria,1U7MT@1239|Firmicutes,4IHJ1@91061|Bacilli,3F9X7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03220 220668.lp_0445 5.08e-194 537.0 28JTN@1|root,2Z9IV@2|Bacteria,1V2P2@1239|Firmicutes,4I4SN@91061|Bacilli,3F9JV@33958|Lactobacillaceae 91061|Bacilli S Psort location Cytoplasmic, score - - - - - - - - - - - - - GHFFDFOM_03221 220668.lp_0446 1.36e-214 593.0 COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,4HAQS@91061|Bacilli,3F3SR@33958|Lactobacillaceae 91061|Bacilli FP exopolyphosphatase ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA GHFFDFOM_03222 220668.lp_0447 1.37e-290 795.0 COG1257@1|root,COG1257@2|Bacteria,1TPNY@1239|Firmicutes,4HBQ3@91061|Bacilli,3F3YY@33958|Lactobacillaceae 91061|Bacilli C Belongs to the HMG-CoA reductase family mvaA - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red GHFFDFOM_03223 220668.lp_0448 4.65e-229 630.0 296WI@1|root,2ZU5A@2|Bacteria,1VT7R@1239|Firmicutes,4HVBN@91061|Bacilli,3F4R1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03224 220668.lp_0449 2.14e-171 478.0 COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,4HC4I@91061|Bacilli,3F4WS@33958|Lactobacillaceae 91061|Bacilli K SIR2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 GHFFDFOM_03225 220668.lp_0450 1.12e-205 568.0 COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,4HA0X@91061|Bacilli,3F40Y@33958|Lactobacillaceae 91061|Bacilli F Protein of unknown function DUF72 yunF - - - - - - - - - - - DUF72 GHFFDFOM_03226 220668.lp_0452 5.43e-91 266.0 COG1051@1|root,COG1051@2|Bacteria,1VKSD@1239|Firmicutes,4HSQ6@91061|Bacilli 91061|Bacilli F DNA mismatch repair protein MutT - - - - - - - - - - - - NUDIX GHFFDFOM_03227 220668.lp_0454 0.0 1375.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,3F3XR@33958|Lactobacillaceae 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind GHFFDFOM_03228 220668.lp_0455 4.08e-270 741.0 COG0477@1|root,COG2814@2|Bacteria,1TR6I@1239|Firmicutes,4HBX6@91061|Bacilli,3F4Q9@33958|Lactobacillaceae 91061|Bacilli EGP Drug resistance transporter Bcr CflA subfamily - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - MFS_1 GHFFDFOM_03229 220668.lp_0456 6.64e-187 519.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,3F3N2@33958|Lactobacillaceae 91061|Bacilli L hydrolase, TatD family tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase GHFFDFOM_03230 220668.lp_0457 1.32e-126 360.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,3F64F@33958|Lactobacillaceae 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 GHFFDFOM_03231 220668.lp_0458 2.5e-203 563.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,3F3VC@33958|Lactobacillaceae 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD GHFFDFOM_03232 220668.lp_0459 6.87e-50 158.0 COG4466@1|root,COG4466@2|Bacteria,1VEQM@1239|Firmicutes,4HKF8@91061|Bacilli,3F7D3@33958|Lactobacillaceae 91061|Bacilli S Biofilm formation stimulator VEG veg - - - - - - - - - - - VEG GHFFDFOM_03233 220668.lp_0460 2.26e-209 578.0 COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,3F43W@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.29 - iYO844.BSU00460 GHMP_kinases_C,GHMP_kinases_N GHFFDFOM_03234 220668.lp_0461 1.9e-230 634.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F57F@33958|Lactobacillaceae 91061|Bacilli S Prolyl oligopeptidase family - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4 GHFFDFOM_03235 220668.lp_0463 8.05e-166 463.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,3F49M@33958|Lactobacillaceae 91061|Bacilli P ABC transporter adcC - - ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 M00242,M00244,M00319 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - iYO844.BSU02860 ABC_tran GHFFDFOM_03236 220668.lp_0464 6.39e-169 474.0 COG1108@1|root,COG1108@2|Bacteria,1V0SX@1239|Firmicutes,4HE09@91061|Bacilli,3F4BC@33958|Lactobacillaceae 91061|Bacilli U ABC 3 transport family znuB - - ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC-3 GHFFDFOM_03237 220668.lp_0466 1.96e-189 527.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli,3F3NH@33958|Lactobacillaceae 91061|Bacilli F pur operon repressor purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N GHFFDFOM_03238 220668.lp_0467 1.34e-297 816.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,3F4I3@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase GHFFDFOM_03239 220668.lp_0469 3.69e-192 533.0 COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,4HFV8@91061|Bacilli,3F5IH@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase enzyme family bla1 - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2,zinc_ribbon_2 GHFFDFOM_03240 220668.lp_0471 3.26e-228 629.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,3F3U2@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N GHFFDFOM_03241 220668.lp_0472 2.82e-236 650.0 COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,4HIW1@91061|Bacilli,3F5KP@33958|Lactobacillaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 GHFFDFOM_03242 220668.lp_0473 4.31e-179 505.0 29NSH@1|root,309QI@2|Bacteria,1U5HU@1239|Firmicutes,4IF8M@91061|Bacilli,3F5ZA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03243 220668.lp_0475 7.18e-192 532.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,3F55S@33958|Lactobacillaceae 91061|Bacilli S hydrolase yxeH - - - - - - - - - - - Hydrolase_3 GHFFDFOM_03244 220668.lp_0476 0.0 913.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,3F442@33958|Lactobacillaceae 91061|Bacilli S HD domain protein ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD GHFFDFOM_03245 220668.lp_0477 8.97e-200 555.0 COG0095@1|root,COG0095@2|Bacteria,1TQKA@1239|Firmicutes,4HCPS@91061|Bacilli,3F575@33958|Lactobacillaceae 91061|Bacilli H biotin lipoate A B protein ligase lipL GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 ko:K16869,ko:K18821 - - - - ko00000,ko01000 - - - BPL_LplA_LipB GHFFDFOM_03246 220668.lp_0479 2.87e-101 293.0 COG4506@1|root,COG4506@2|Bacteria,1V8IZ@1239|Firmicutes,4HIW0@91061|Bacilli,3F6AI@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1934) ywiB - - - - - - - - - - - DUF1934 GHFFDFOM_03247 1136177.KCA1_0413 2.96e-89 267.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,3F55D@33958|Lactobacillaceae 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE - - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH GHFFDFOM_03248 220668.lp_0481 0.0 1061.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,3F42X@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase GHFFDFOM_03249 220668.lp_0501 5.84e-312 849.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,3F3M6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b GHFFDFOM_03250 220668.lp_0502 2.28e-290 795.0 COG0814@1|root,COG0814@2|Bacteria,1V00Q@1239|Firmicutes,4IF7J@91061|Bacilli,3F5WK@33958|Lactobacillaceae 91061|Bacilli E amino acid sdaC - - ko:K03837 - - - - ko00000,ko02000 2.A.42.2.1 - - Trp_Tyr_perm GHFFDFOM_03251 220668.lp_0505 7.51e-159 444.0 COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,4HBD6@91061|Bacilli,3F4UB@33958|Lactobacillaceae 91061|Bacilli E Serine dehydratase beta chain sdhB - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - ACT,SDH_beta GHFFDFOM_03252 220668.lp_0506 2.81e-202 561.0 COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli,3F3X8@33958|Lactobacillaceae 91061|Bacilli E L-serine dehydratase, iron-sulfur-dependent, alpha subunit sdaAA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha GHFFDFOM_03253 220668.lp_0507 6.59e-170 474.0 COG2964@1|root,COG2964@2|Bacteria,1V2VD@1239|Firmicutes,4HHYZ@91061|Bacilli,3F5VW@33958|Lactobacillaceae 91061|Bacilli S YheO-like PAS domain - - - - - - - - - - - - HTH_22,PAS_6 GHFFDFOM_03254 220668.lp_0509 4.01e-36 122.0 2BW8P@1|root,30AMZ@2|Bacteria,1U6VX@1239|Firmicutes,4IGPZ@91061|Bacilli,3F8KF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03255 220668.lp_0510 2.08e-302 825.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,3F3P8@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase GHFFDFOM_03256 220668.lp_0511 6.26e-306 834.0 COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,4H9XB@91061|Bacilli,3F43Y@33958|Lactobacillaceae 91061|Bacilli K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind GHFFDFOM_03257 1136177.KCA1_0423 1.91e-55 172.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HKF0@91061|Bacilli,3F7D7@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L31 rpmE2 - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 GHFFDFOM_03258 220668.lp_0513 2.57e-274 750.0 COG1503@1|root,COG1503@2|Bacteria,1UHSE@1239|Firmicutes,4HEGH@91061|Bacilli,3F5YK@33958|Lactobacillaceae 91061|Bacilli J translation release factor activity - - - - - - - - - - - - - GHFFDFOM_03259 220668.lp_0514 3.14e-164 459.0 COG3764@1|root,COG3764@2|Bacteria,1V83Z@1239|Firmicutes,4HJV9@91061|Bacilli,3F54V@33958|Lactobacillaceae 91061|Bacilli M sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase GHFFDFOM_03260 220668.lp_0515 5.35e-121 346.0 COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,4HH6H@91061|Bacilli,3F4TF@33958|Lactobacillaceae 91061|Bacilli S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA GHFFDFOM_03261 220668.lp_0516 7.59e-193 537.0 COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli,3F40Z@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 GHFFDFOM_03262 220668.lp_0517 1.84e-189 525.0 29SV9@1|root,30E1E@2|Bacteria,1V46E@1239|Firmicutes,4HI7R@91061|Bacilli,3F6E2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - GHFFDFOM_03263 220668.lp_0518 0.0 899.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,3F4SK@33958|Lactobacillaceae 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M GHFFDFOM_03264 220668.lp_0520 0.0 969.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,3F46Q@33958|Lactobacillaceae 91061|Bacilli F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C GHFFDFOM_03265 220668.lp_0522 9.32e-81 239.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli,3F6HC@33958|Lactobacillaceae 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS GHFFDFOM_03266 220668.lp_0523 5e-275 751.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,3F3X2@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N GHFFDFOM_03267 1136177.KCA1_0440 4.28e-84 248.0 COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,4HGXF@91061|Bacilli,3F6Y9@33958|Lactobacillaceae 91061|Bacilli L Toxic component of a toxin-antitoxin (TA) module ndoA - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin GHFFDFOM_03268 220668.lp_0525 0.0 1267.0 COG3158@1|root,COG3158@2|Bacteria,1TRUQ@1239|Firmicutes,4HA8Z@91061|Bacilli,3F4CU@33958|Lactobacillaceae 91061|Bacilli P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans GHFFDFOM_03269 220668.lp_0526 0.0 1962.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS GHFFDFOM_03270 220668.lp_0527 9.1e-261 714.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,3F43R@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase GHFFDFOM_03271 220668.lp_0528 3.61e-244 671.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,3F5DZ@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11190 Semialdhyde_dh,Semialdhyde_dhC GHFFDFOM_03272 220668.lp_0529 9.73e-294 801.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,3F433@33958|Lactobacillaceae 91061|Bacilli E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ GHFFDFOM_03273 220668.lp_0530 2.36e-166 466.0 COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,4HH91@91061|Bacilli,3F5QN@33958|Lactobacillaceae 91061|Bacilli F Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase GHFFDFOM_03274 220668.lp_0531 4.47e-276 755.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli,3F52J@33958|Lactobacillaceae 91061|Bacilli E acetylornithine argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 GHFFDFOM_03275 220668.lp_0532 2.63e-241 663.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,3F48K@33958|Lactobacillaceae 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N GHFFDFOM_03276 220668.lp_0533 1.3e-110 318.0 COG4708@1|root,COG4708@2|Bacteria,1V463@1239|Firmicutes,4HH0P@91061|Bacilli,3FCEF@33958|Lactobacillaceae 91061|Bacilli S QueT transporter queT - - - - - - - - - - - QueT GHFFDFOM_03277 1291743.LOSG293_080270 1.06e-210 602.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F4TA@33958|Lactobacillaceae 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GHFFDFOM_03278 1291743.LOSG293_080280 8.1e-157 447.0 COG2267@1|root,COG2267@2|Bacteria,1U46W@1239|Firmicutes,4IDY6@91061|Bacilli,3F5ZW@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates pepL - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 GHFFDFOM_03279 220668.lp_0535 4.87e-148 417.0 COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,3F3JY@33958|Lactobacillaceae 91061|Bacilli S (CBS) domain - - - - - - - - - - - - CBS GHFFDFOM_03280 220668.lp_0536 0.0 919.0 COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,4HDTN@91061|Bacilli,3F3QW@33958|Lactobacillaceae 91061|Bacilli S Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_4,YkuD ## 3082 queries scanned ## Total time (seconds): 2.8305883407592773 ## Rate: 1088.82 q/s