LOCUS       c00028_gnlPro..        15917 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BAHNCBHM_28.
ACCESSION   c00028_gnlPro..
VERSION     c00028_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 04:26:45
            Original ID  :: gnl|Prokka|BAHNCBHM_28
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15917
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1674)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.1e-40, bitscore:
                     127.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEKINAADAMIKVLEDWGIHNIYGLPGGSFDSTMNALYNRRHTI
                     NYVQVRHEEVGALAAAGEAKVTGRIGATFGSAGPGAVHLLNGLYDAQYDHVPVLALVGQ
                     VPTAAMNTNYFQEMNENPMFADVSVYNRTAMTAAQLPHVVDEAIRQAYKYQGVAVVTIP
                     KDLGWQEIDDNYVSSANLYQKPLLPEPDPEQVATAWSILKDAKKPILYVGNGARGARDE
                     IIAFSEKTHIPIITTALAKGIVPDDYKANMGSAGRVASKPGVEVARGADTVLFLGSDFP
                     FQPYFIAPNAKYIQVDIDASKFGRRHTVDLAVLADAKKFIKALTEKADAVPETAWYRAA
                     VANKANWAEWMTSFEDDPQTPLRVEPIFKLINEMADKDAVFQVDVGNVTINGMRYLKAN
                     DNQIFTTSGWYATMGYAVPAAIGAQAEFPDRQVWSISGDGGFAMVMQDIMTQVKYHMPI
                     INIVLTNESLGFIEAEQDDTRQPHSGVDLIDADYGKAAEAMGAQGFEVHNLDELKAAFA
                     KAKDRKGPVVIDVKISDLRPIPVEQLVLDKQTQDPEAVDAF"
     protocluster    1..15917
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:5917]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..5917
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..15917
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15917
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(1775..2011)
                     /locus_tag="ctg28_2"
                     /transl_table=11
                     /translation="MKKREPARNALKRVITIRIRRYLKWIKMATEIFKSKYSLLTNYLE
                     RTGSVSVSLIDCYYLGVGIMTMTKTLSLLLAVT"
     CDS             complement(2287..3459)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ACP_syn_III"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_3"
                     /sec_met_domain="ACP_syn_III (E-value: 6.2e-09, bitscore:
                     26.7, seeds: 136, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIGIDAIEMDTPDFYVDLVKLAKVRGDDPNKYTIGIGQDEQAVP
                     PSSQDIVTLGANAAAKVLTPASRASLGMILVGTESGVDASKSAALFIHDLLALPEWVRA
                     VELKEACYGGTAALMMARDYVASHPDKSVLVIAADIARYGLATAGEVTQGAGAVAMIVK
                     ADPCLLTIEPDSVYRSASINDFWRPVYQDTALAQGKYSTEQYLAFFKTVWERYQADHHL
                     SAHDFAAMTFHLPYTKMGKKALDLVLPTTDDASAQRLKNRFEASTRYCRRIGNIYTGSL
                     YLGLLSLLDHDTTLQAGDRIGLFSYGSGAVAEFFSGILQPQFKEQLHAAEHAQQLTKRQ
                     ELPVPEYEAVFSDKVPYDADDYRPDPAYYRGQFILTGVIGQERHYEKHQS"
     CDS             complement(3479..4723)
                     /locus_tag="ctg28_4"
                     /transl_table=11
                     /translation="MKFYEQTPEARRHQLVQEGSLTSTDAALLAAARTLPDATATRLIE
                     NAIGEFSLPMGIARNLMVNGQQHQVPIVNEEPSVVAAASNGARMVAENGGVLAHVGTHE
                     VVAEVVLTDLADLNTARQILLAHQATIAAVANAAHPSMVQRGGGFRNLTVTILANRFLK
                     LRLTLNPKAAMGANYANTVAEAVADAVTTWVDGTVLASILTNAPSELVTATVKLTPATL
                     ATKTLSGDEIAHKIVQLSDLAFVDPERAVTHNKGILNGVIGAVLATGNDTRAVAASVGA
                     FAAATGQYQPLSRWLMRDGKLEGYLQMPLPLGAVGGAIGALPLAQAARRLGGYRDLATM
                     QQVIAALGLVQNLAALRALAGPGIQSGHMKLQANALAIAAGAQDQEVPALVAALRAGEM
                     DLAHAKMYLATIRSK"
     CDS             complement(4736..5917)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: Thiolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_5"
                     /sec_met_domain="Thiolase_N (E-value: 7.5e-96, bitscore:
                     311.3, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 2.2e-45, bitscore:
                     144.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKVVILSAKRTPIGKLGGELAGASAVDLGVTAAKAAIKAARLDP
                     QQLDQAIFGNVLQAGSGQNVARQIALHSGMATNSTAMTINEVCGSGLKAIRLGQAAIQL
                     GEANAVLVGGTESMSQVPYYAEAMRAGHKFGDTALVDGLSRDGLNDAFSQQPMGITAEN
                     VASRFQISRQAQDEFALRSHLRAAAAAAEGRFKSQIAPVTISGRHGDVTIDTDSAIRPD
                     TSLAQLAKLPPVFEVGGTVTAGNASGINDGAAALILMAKSKAEQLGLHYLATITDYTEV
                     GIDPDIMGYAPKLAIDQLMQKTGQTLTAIDQVELNEAFASQSVAVMRDLGLTDEQVNIN
                     GGALALGHPLGASGARIMVSLLYNLAERRQQTGIAALCVGGGIGMAMQVTLHD"
     CDS             6511..6810
                     /locus_tag="ctg28_6"
                     /transl_table=11
                     /translation="MRVIDLLALLADQSKNAPVLLNTTPAPSRFDDFILKTQNDQPQLI
                     FKPKPDRKSPLRVWELQLLLNQPDLQSRFLYLADAGGTRALFGFIHRPVGLLLN"
     CDS             complement(6807..7637)
                     /locus_tag="ctg28_7"
                     /transl_table=11
                     /translation="MLLGLKASTDERQIRDRLQYHPDVFEFHLTEADFTASGWQHFLKM
                     VAWVQSQVPTVVFHHPMRFRGQRNELAMNPTKYPARYDFLMTSSVKLMTLAKKVNATAL
                     IHGGYRVDTPGDYAGWRDVAKAQDVALARMIAFAQEAPGHVVFENSMSPIFRYGDPAFE
                     ARLLRWRLPLAYDTSHTFITLRGDNERLIASLRNLKPLVRHYHLVDSMGQTHDSLPLGE
                     GRIDWYRVLPQLNPNASRIYEIGLKNQFDCQEMIASHHYLEKVAAKLAAAKHPA"
     CDS             complement(7671..8234)
                     /locus_tag="ctg28_8"
                     /transl_table=11
                     /translation="MRILLKKAYHLLWGLFVLALIYSFWARTILPRQLRPYGDPASFTI
                     ISLFVVINALLLYHHHFRFRDLKMESVDIMEGEKFEEFCAYLLKRNGFKRIQLTQASGD
                     QGIDIIAQKKGQSFGFQCKRYTGFVGNKAVQEVWAGHHYYQLDQAAVITNSEFSDSAIA
                     LADDLGVMLIDRKKLKRLMRRLPS"
     CDS             complement(8496..8630)
                     /locus_tag="ctg28_9"
                     /transl_table=11
                     /translation="MQTWRESARLDKDHVFDGVKIACVAAACGHHNALPGAEVGSRSP"
     CDS             8689..9522
                     /locus_tag="ctg28_10"
                     /transl_table=11
                     /translation="MKLSAKIFAKVGSERITQYTLVNDQQMTLRFLTFGARVQQVRLPT
                     TTGLDPNLLLGFVTLEDYLHQPGLFGAMTGPLAPDDPKTIPGAWQNWNWAVKTSQTADL
                     AITFSLNLPENADGQPGERSLMVTHRLNNDNVWTIDMAVKTTAEIRLHPRLILPWLLTA
                     DPAQTMLHAQLTIDHQQSTIKQQPEISPAHRFSLATGDWQLHYATDAPATRIDSFANIG
                     PDNNFNGILGQPHVAIGFSPENNLTGNAWTLAAGATWQHHAEYQLSRIKASTPDR"
     CDS             complement(9619..10788)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_11"
                     /sec_met_domain="Peptidase_M20 (E-value: 9.3e-39, bitscore:
                     124.2, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYFKSGGGSLTDEEQQVTDLLQAMVRIPSVAAKEGQVADLIEAFL
                     APELSAGLIKRERISYAPGRDNLVLTIGDSNAQRWLGVDGHMDVVDAGDPNKWQFPPFS
                     AQIEDGKLYGRGATDMKSGLAAAVVAFKQIAHEELDHGVQLMATVGEEIDNYGARQLAA
                     AGYGDRLTGLLVAEPGNSNVDAAERGIIDYTLTAQGKAAHSSRPDLGANAIHGLFAFAN
                     AALTATAPLQAKDDPILGHATHNIDIIHGGNQINSLPESAYLRGNIRTTMIADNDAFIA
                     ALKQAAKTSVPKGVHLSLSIDSVLSAAAAAPDNALIQKVQQARQRIGLQRGAVAYRTGI
                     TDAALFFHDGLDLAIYGPGNDTSHETDEYVDLQDVFDSIKVYKDVFKNY"
     CDS             complement(10893..11498)
                     /locus_tag="ctg28_12"
                     /transl_table=11
                     /translation="MTRRGKAYNIAIIGILGALIILQAYIPMVGYVQIFPAWPAISTIH
                     LTVIIGGIVLGYGGGASLGLLWGLTSLIRAYTSAADPVTLLLFRNPIIALVPRVMVGLV
                     AAFVFHQLFKRHQSTLAQTIKMVIAGVAGALTNTLLVIGFTWLLFASKAAQIVPGANAT
                     NLGWLLITALAINAVAEAVLGGIVTPILGQALLRFRRK"
     CDS             12199..12663
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_13"
                     /sec_met_domain="Acetyltransf_1 (E-value: 7.8e-18,
                     bitscore: 55.8, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLREAQFVDLPAIVHLYQQLTQEMAALAPDTYRPLTTDNRQYFAD
                     YLQNDLARLFVTESQGTLTGFALVVLARTGDSPEFVPQHFAQLIDLFVTPDHRHHGLAK
                     TLMTAVEAFAASHQASFIQLNVLSGNQTAREVYARAGFQPVNLILQKPLN"
     CDS             complement(12660..13112)
                     /locus_tag="ctg28_14"
                     /transl_table=11
                     /translation="MTNQELQARVEAISMSAFHQPFNHQAVFNARLRTTGGRFYPATMN
                     LDFNPKIFALYPSDVTDGIIKHELVHYHLFAQHRGYQHRDHDFKQLLAAVGGSRFAPSL
                     PMNGRHYVYQCTRCGRQFVRRRRINVNRYACGVCRGKLRLQATRNN"
     CDS             complement(13360..14112)
                     /locus_tag="ctg28_15"
                     /transl_table=11
                     /translation="MAELKLDHVTVNVPVATQVKTLLQDVTLTVKTGEFVTVLGHNGAG
                     KSTLFNAITGDLPVSGGTVTLAGQTLNGRRPEQRARHIARVFQDPKMGTAPRMTVAENL
                     LLASHRGQRLGLRSRGLNAQKAQLKALAAKTGNGLAEALDKPTEQLSGGQRQALSLLMA
                     TMRKPDLLLLDEHTAALDPHTSQAIMALTNAIVSEQQLTCLMITHQVEDALRYGNRLIV
                     LDAGQIVADFDQKRKAALKRADVLAFFN"
     CDS             complement(14105..15004)
                     /locus_tag="ctg28_16"
                     /transl_table=11
                     /translation="MSLGVSAIGQGLLYGLIGLGLFLTFRVLDFPDMTVEGTFPFGAAV
                     AVSAITHGISPIIATLLATVAGMLAGLVTGLLTTKGRIPVLLAGILVMTGLFSINLRIM
                     GRANLSLLHQANLFQGSFLKDLPPYFNSVVVGLIVVVIVVGLLMLFLNTQLGQGFIAAG
                     DNPNMARSLGINPDHQMVLGLMVGNGLVGLAGGLLAQNNGYADVNMGIGIIVIGLAAII
                     IGEVVFGELTLSQRLVAVILGSIIYRFVLLVVLALGFNADDLKLISAVVLAIAIMVPQI
                     DHQLRLRRVLQKGVQIHG"
ORIGIN
        1 gaatgcgtca acggcttctg gatcctgcgt ttgcttatcc aaaaccagtt gttcaaccgg
       61 aattggccgt aaatcggaaa tcttcacgtc aatgacaact gggcctttac gatccttggc
      121 ctttgcgaat gccgccttga gttcgtccaa attatgaact tcaaaccctt gtgcgcccat
      181 cgcttcagct gccttgccat aatcagcatc aataagatca acccctgaat gcggctgacg
      241 ggtatcgtct tgttccgctt caataaagcc taaactttca ttggtcaaaa caatgttgat
      301 aatcggcatg tgatacttca cttgagtcat aatatcctgc atgaccatcg caaacccgcc
      361 gtcacctgaa attgaccaca cttgccgatc cgggaattca gcttgggcgc caattgcagc
      421 aggtacagca tagcccatcg ttgcgtacca gccggaagtc gtaaagattt gattatcgtt
      481 ggccttcaaa taacgcatgc cattaatcgt tacgttaccg acgtccacct ggaaaaccgc
      541 atctttgtcg gccatctcgt tgataagttt gaagatcggc tcaacgcgca atggggtctg
      601 cggatcgtct tcaaatgacg tcatccactc agcccagttt gccttgttag caaccgcagc
      661 gcgataccaa gcagtttccg gtacggcatc agccttttcg gtcaatgcct tgatgaattt
      721 cttggcatcg gctaaaaccg ccagatcaac tgtgtgccgc cgcccaaact tgctagcatc
      781 aatatcgact tgaatatact tagcatttgg cgcgataaag taaggctgga atgggaagtc
      841 agagccaagg aacaaaaccg tatcggcgcc gcgggctact tcaacccccg gctttgatgc
      901 aacccgaccg gcagatccca tgttggcctt ataatcatct ggcacaatgc cttttgccag
      961 tgcggttgtg atgatcggga tatgcgtttt ttcggaaaat gcaatgattt catcgcgagc
     1021 tccacgcgca ccattaccaa cgtataggat cggctttttg gcatccttta aaatgctcca
     1081 agcggttgcc acttgctccg gatccggttc aggcaataac ggcttttgat aaagattagc
     1141 cgatgaaaca taattatcat cgatttcctg ccaaccgaga tccttaggaa tggtcacaac
     1201 agcaacgcct tgatacttat aagcttggcg gatggcttca tcgacaacgt gcggcaattg
     1261 tgcagccgtc atggcagtcc gattataaac cgatacatcg gcgaacatcg ggttttcatt
     1321 catttcctga aaatagttgg tattcatggc tgcagtcggc acctggccta ccaatgctaa
     1381 taccggtaca tgatcgtatt gcgcatcata taaaccgttt aacagatgaa cggcaccagg
     1441 acctgctgac ccaaacgtgg ccccaatgcg tcccgttacc tttgcttcgc cagccgcagc
     1501 caatgcgccc acttcttcat ggcgaacctg cacgtaatta atggtgtggc ggcgattgta
     1561 aagcgcgttc atggtgctat caaacgatcc gcccggcaat ccataaatat tatgaattcc
     1621 ccagtcttct aacaccttga tcattgcgtc tgcagcattg attttttctg tcatgacact
     1681 tgcctccatt attacttaca ttttgtaagt tctttacgat tatgagtata acaattaatc
     1741 aataacaatg caaacccttt cactcgattc gagatcaagt cacggctaaa agtaaggaaa
     1801 gcgttttagt cattgtcatt atacccacgc caaggtaata acagtcaatc aaactgactg
     1861 atacagagcc tgttcgttcc agatagtttg ttagcagact gtattttgac ttaaatattt
     1921 ccgtggccat ttttatccat ttcaaataac ggcggattct aattgttatc actcgcttta
     1981 acgcgttccg cgccggctcg cgcttcttca taacgcgctc cccagcgcag ggatctgcgt
     2041 gtaaggaccc cgaacgcaat ggccaaagcc cggccatcac gttcgaggcc gcttacactc
     2101 cgatccctaa ccgcgccggc tcgcgctcac acaaaaaacg aatgaacgat tccatttaat
     2161 cggaaaagtc cattcgcttt ctatgactct tttacatggc gccgaccgaa aataattatc
     2221 aactaaaaaa ttggcgctta ttaattctga ccagacaaaa ctaccttaac ttttacaccc
     2281 ggttcatcac gattggtgtt tttcgtagtg ccgctcctgg ccaatgacac cggtcaaaat
     2341 aaactgacca cgatagtatg ccggatcagg gcgatagtca tcggcatcat acgggacttt
     2401 atcgctaaag accgcttcgt attccggtac aggcagttct tggcgtttag ttagttgctg
     2461 ggcatgttcg gcggcgtgta gttgttcctt aaattgtggt tgcaaaatgc cgctgaagaa
     2521 ctctgcgacg gcaccggaac catacgaaaa cagtccgatc cgatccccgg cttgtagcgt
     2581 cgtatcatga tccagcaacg acaacaaccc cagataaagc gaaccagtgt aaatattgcc
     2641 aattcgccga caataacgcg tgctggcttc aaaacggttt ttcaatcgct gggcactcgc
     2701 gtcatcggtg gttggcaaca ctagatccaa tgctttttta cccattttgg tatatggcag
     2761 atggaatgtc attgccgcga aatcatgtgc acttaaatga tggtcggcct gataacgttc
     2821 ccagactgtc ttgaagaagg cgagatattg ttcggttgag tattttcctt gagcaagcgc
     2881 cgtatcttgg taaaccggtc gccaaaagtc gttgattgat gccgatcgat aaaccgaatc
     2941 cggttcaatt gtcagcagac acggatcagc tttgacaatc atcgccactg cgccggcccc
     3001 ttgcgtcact tcaccggccg ttgctaatcc ataacgcgca atatctgccg caataacgag
     3061 cacactttta tcaggatgac tcgcaacata atcacgagcc atcataagcg cagcggtccc
     3121 gccataacaa gcttctttca gttcaaccgc ccgcacccat tcaggcagtg ccaaaagatc
     3181 atgaatgaat aaggcggcgg atttactagc atcaaccccg ctttcggttc caaccagaat
     3241 catgcctaaa ctggcacgtg atgctggcgt caatactttt gcggcggcat tggctcccaa
     3301 tgtcacaatg tcttgactag atggcggaac cgcctgctcg tcttggccga tgccgatcgt
     3361 atatttattc ggatcatcac cgcgaacctt ggcaagtttt acgagatcga cgtaaaagtc
     3421 cggggtatcc atttcgatgg catcaattcc gattttcata atttcaatgg cctgctttct
     3481 attttgatcg aatcgttgct aaatacattt tggcatgtgc cagatccatt tcacctgcgc
     3541 gtaaggcggc gactagagca ggtacttcct gatcctgagc tccggcagca atcgccagtg
     3601 cattggcctg cagtttcata tggcctgact gaatgccggg gccggctaat gcgcgcaaag
     3661 ccgctaaatt ctgcactaat cctaatgcgg caattacctg ctgcatggtg gctaagtcgc
     3721 gataacctcc aagacggcgg gccgcctggg ctaatggtaa tgcaccgatc gcgcctccga
     3781 cagcacccag cggcaatggc atttgcagat agccttcaag tttgccatcg cgcatcaacc
     3841 aacgtgataa cggttgatac tgaccagtcg cagcggcaaa cgccccaaca ctggccgcaa
     3901 ccgcgcgcgt gtcatttccc gtcgccaaga ccgccccaat aacaccgtta agaatgcctt
     3961 tgttatgcgt caccgcgcgc tctggatcga caaatgccaa atcgctcagc tgcacaattt
     4021 tatgggcaat ttcatcccct gacagtgttt ttgtggcaag tgtcgccggt gtcaatttca
     4081 cagttgctgt gactaactcg ctcggtgcgt tagttaaaat gctggccaaa accgttccat
     4141 ccacccaggt tgtcactgca tctgccacag cttcggcaac cgtattcgca taattggcgc
     4201 ccatcgccgc tttaggatta agcgtcaggc gaagttttaa aaaccggttg gccaagattg
     4261 tcacggtcag gttgcggaag cctccgccac gctgcaccat tgagggatgg gcggcattgg
     4321 ccacagctgc gatcgttgct tgatgggcca aaaggatctg tctagccgta ttcaaatctg
     4381 ctaaatcagt taagaccact tctgccacca cttcatgggt acccacatgc gctaaaacgc
     4441 cgccgttttc cgctaccatt cgcgcaccat tgctggccgc agcaacaaca gagggttcct
     4501 cattaacaat cggtacttga tgttgctggc cattgaccat taaatttcgc gcaatgccca
     4561 tcggtaagga aaattcacca attgcatttt caatcaaccg agtcgcagta gcatcaggaa
     4621 gcgtgcgtgc cgcagccaat aaagcggcat ctgtactggt taatgaccct tcttgcacaa
     4681 gttggtgccg cctagcttcg ggcgtttgct cataaaactt cattttaatc tgctcctaat
     4741 catgcaaagt aacttgcatc gccataccga taccaccacc gacacataac gccgcgatac
     4801 cggtttgttg cctgcgttcg gccagattat acagtaatga aaccataatc cgcgcgccgg
     4861 atgctcccaa gggatggcct aaagcaagcg ctccgccatt gatattcacc tgttcgtcag
     4921 tcagtcctaa gtcacgcatc acggcaacac tttgcgaggc gaatgcttca tttaattcca
     4981 cttgatcaat ggctgttaaa gtttgtccgg ttttttgcat tagctggtca atcgctaatt
     5041 taggcgcata acccatgatg tccgggtcaa tcccgacttc tgtatagtca gtgatggtag
     5101 ccaaatagtg gaggcctaac tgctcggctt ttgacttcgc cataagaatc aatgcagccg
     5161 ccccgtcatt aatcccgcta gcattacccg ccgtgacggt accgccaact tcaaaaactg
     5221 gcggtaattt tgctaactgg gctaatgatg tatccggtcg aatcgccgaa tccgtgtcaa
     5281 tcgtgacatc gccatgtcgg ccggaaatgg tcaccggtgc aatttgtgat ttaaaccggc
     5341 cttctgcagc agcagcggcc gcacgcagat gagagcgcag tgcaaactcg tcttgcgctt
     5401 gacgactgat ctgaaagcgg ctggcaacat tttccgccgt aatccccatc ggttgctgac
     5461 taaaagcatc gtttagccca tcgcgactaa gaccatccac caacgcagta tcgccaaact
     5521 tatgcccggc ccgcattgcc tcagcataat acggtacctg actcatactc tcggtaccgc
     5581 cgacaagtac cgcgttagct tcacctagtt gaatcgccgc ctgacctaac cgaattgcct
     5641 ttagcccaga gccgcaaact tcattgatcg tcatggccgt ggagttcgtc gccatgccac
     5701 tatgcaacgc aatctgccgc gcaacattct ggcccgatcc agcctgcaaa acattcccga
     5761 aaattgcttg atccagttgt tgcggatcaa gccgtgctgc tttaatcgcc gccttagctg
     5821 cagtaacacc taaatccact gcactagcac ctgctaactc accgcccaac tttccaatcg
     5881 gcgtccgctt ggcactaaga atcacaactt tttccataat aacccctttt caaaatgtga
     5941 gcgcgagccg gcgcggttag aagtcggagt gtaagtggcc ttgggcgtga tgaccgcttt
     6001 ttggtcattg cgtccaaggt ccttacacgc agacttctgc gccggggagc gcgttatggt
     6061 gagcgtgagc cagcccggtt agaaaccgga gcataagtgg ccttgggcgt gatgaccggg
     6121 ctttggtcat tgcgtccaag gtccttatgt gcaggtttct gggctggcga acgcgttatg
     6181 gtgagcgcga gccgcccagt caagaaccca attcaaacat gcgttataat acatcgaaga
     6241 agatcccatc gctgacctga gcaaccgcta cataacacca atgcccgctc agaaaaaccg
     6301 ttatagttta tcacagtccg aaaaacaaaa catctaaatc gtggcttgca ccgttaatcg
     6361 cccagattcc ggtcccttta gccgagattg catttatgtc tagctacata agttcatgtt
     6421 aaactgttta aattgtatgc gattcttttc ggaagtaaca cccgtcttca ccaatcctta
     6481 acttttagcc atagaaagta ggtgccgttg atgcgcgtca ttgatttgct cgccttactc
     6541 gctgaccaaa gtaaaaacgc cccagtactg ttaaatacaa caccagcacc aagtcgtttt
     6601 gatgatttta ttttgaaaac ccaaaatgat cagccacaat taatctttaa gcccaaacct
     6661 gatcgaaaat cgccattacg cgtgtgggaa ttacaacttt tgttaaatca gcctgactta
     6721 caatcacgtt ttctttatct tgcagatgca ggcggcaccc gtgcactttt tggctttatc
     6781 caccggccag ttggtctttt gcttaactag gccggatgtt ttgccgccgc caactttgct
     6841 gcaacctttt ccagataatg gtgactggct atcatttctt ggcaatcaaa ctgatttttc
     6901 aaaccgattt cgtaaatccg gctggcgtta ggattgagct ggggtaaaac gcggtaccaa
     6961 tcaattcgac cttctcccaa aggtaaactg tcatgcgtct gccccattga gtcaaccaaa
     7021 tgataatgcc gtactaatgg ttttaggttg cgcagactgg cgataagtcg ctcattatcc
     7081 ccgcgtaacg tgataaaagt atggctagta tcataagcca atggtagccg ccagcgcagt
     7141 aaacgcgcct caaacgcagg atcgccatac ctaaagattg gcgacatcga gttttcaaat
     7201 accacatgtc ccggcgcctc ttgagcaaac gcaatcatgc gagccaatgc cacatcttgt
     7261 gcttttgcaa cgtcacgcca tccggcataa tctccggggg tgtccacgcg gtaaccaccg
     7321 tgaatcagtg ccgtggcatt cactttttta gccagtgtca taagcttaac ggaactggtc
     7381 atcagaaagt catacctggc tggatattta gtcggattca tcgctaactc attgcgctga
     7441 ccacgaaatc gcatcgggtg gtgaaaaaca acagtcggca cctgactttg aacccaggca
     7501 accattttca aaaaatgttg ccagccactc gccgtaaaat ctgcttccgt caagtgaaac
     7561 tcaaaaacgt caggatgata ctgcaatcga tcacgaatct ggcgctcatc ggtactggct
     7621 tttaaaccca acaacatgaa ttgccaacct ccttaaaagc aatgaccatt ctagctcggt
     7681 aatctgcgca tcaagcgttt aagcttcttg cgatcaatta acatcacccc caggtcgtca
     7741 gctaaggcaa tcgcggagtc ggaaaactca ctgttggtga tgaccgcagc ttgatcaagt
     7801 tgataataat gatgccctgc ccaaacttcc tgaaccgcct tattcccaac aaagccagtg
     7861 tatcgcttac attgaaagcc gaatgactgg cctttttttt gtgcaataat gtcaatgcct
     7921 tgatcacccg aagcctgagt aagttgaata cgcttgaagc cattgcgttt taataaatag
     7981 gcacaaaatt cctcaaactt ctcaccttcc atgatgtcca cgctctccat cttcaaatct
     8041 cgaaaccgaa aatgatgatg gtacagcaac aacgcattga tcaccacaaa taaactaata
     8101 atagtaaaac tggcaggatc gccataaggt cgcaactgcc gaggcaaaat agtgcgggcc
     8161 caaaaactat aaataagggc caatacaaac aacccccaca acaaatggta ggccttttta
     8221 agtaaaattc tcatgcttct aaacccttct agttaagtga gcgtgagcca gcccggttag
     8281 aaaccggcgc ataagtggcc ttgggtgtga tgaccgggct ttggtcattg cgcccaaggt
     8341 ccttatgtgc aggtttctgg gctggcgaac gcgttatgag cgtgaaccgg cgcgcttagg
     8401 gatcggagtg taagtggcct tgggcgtgat ggcgcctggg cttggccatt gcggctgagg
     8461 tcctttacac tccgatccct gcgccggtga acgcgttatg gtgagcgtga tccgacttct
     8521 gcgccgggga gcgcgttatg gtgaccgcaa gccgccgcga cacacgcgat cttcacacca
     8581 tcaaatacat gatccttatc aagcctagca gattcacgcc atgtttgcat tgaaactcag
     8641 gtaatttttc tgtaggctta atttattgag aagggaagcg ttttcgtcat gaaactaagc
     8701 gccaaaattt ttgccaaagt tggcagtgag cgcattacgc aatacacatt agttaacgat
     8761 cagcaaatga cgctgcgatt tttaactttc ggcgctcgtg ttcagcaagt ccggttgccc
     8821 actacgactg ggttggatcc taacttattg cttggattcg tcactttaga agactatctg
     8881 catcaacccg gtcttttcgg cgccatgacc ggtccgcttg caccagatga ccctaaaacg
     8941 atccccggag cttggcagaa ttggaattgg gcggtgaaaa ccagtcaaac ggctgactta
     9001 gccattacct tttctctaaa tttacctgaa aacgctgatg gacaaccggg cgagcgctcc
     9061 cttatggtta cgcaccgact gaataatgac aatgtctgga ccatcgatat ggccgttaaa
     9121 accactgccg aaatccgact tcatccacga ttgatattgc catggttatt gacagccgat
     9181 cccgcccaaa caatgttaca cgctcagtta accattgacc accagcaaag taccatcaag
     9241 caacagccag aaatctcgcc tgcacataga ttctccttag ccaccggtga ctggcaactg
     9301 cactatgcca ccgatgcgcc ggccacccgc attgactcgt ttgctaacat cggacccgat
     9361 aacaacttta acggcattct gggacaacct catgttgcaa tcggattttc tcccgaaaac
     9421 aatttaaccg gcaacgcgtg gacacttgct gccggcgcaa cttggcaaca ccacgctgaa
     9481 tatcagttga gcaggattaa ggccagtacg ccagaccgtt aatccaatca gctaaccaaa
     9541 ctaatcgcta caaaaagcct tggacgttga atgagctgct caccgtcaca aggctttttc
     9601 tactggtatt agttgacact aataattttt aaagacatct ttgtaaacct taatactgtc
     9661 gaacacgtct tggaggtcaa catattcatc ggtttcgtgc gaagtgtcat tacctggccc
     9721 gtaaatagcc aagtccaaac catcgtggaa aaataaggcc gcatcggtta tgccggttcg
     9781 ataggccaca gccccgcgct gcaaaccgat ccgctgccgt gcctgctgga ctttttgaat
     9841 taacgcatta tcgggtgcag ccgctgcggc acttaaaacc gaatcaatcg aaagtgatag
     9901 gtgaacccct tttggtactg atgttttagc agcctgcttc aaagcggcaa taaacgcatc
     9961 attatcagca atcatggttg ttcggatgtt gccgcgtaaa taagcagact ccggtaatga
    10021 attaatctga ttcccgccat ggataatatc gatgttgtgg gtagcgtgac ccagaatcgg
    10081 atcatcttta gcttgaagcg gcgcggtggc agttaatgcg gcattggcaa aagcaaataa
    10141 gccgtgaatg gcattagccc caagatctgg acgtgaagaa tgcgccgcct tgccctgagc
    10201 cgttaacgta tagtcaataa tgccacgttc agccgcatcc acattgctgt ttcccggttc
    10261 tgcgaccaaa agaccggtca accgatcacc ataaccggca gccgcaagtt ggcgggcacc
    10321 gtagttatcg atttcttcgc ccacggttgc catcaactga acgccatgat caagctcttc
    10381 atgcgcgatt tgcttaaacg caaccacagc agcggcaagt ccggatttca tatccgtcgc
    10441 cccgcggcca tacaatttac catcttcaat ctgggctgag aacggaggaa actgccactt
    10501 gttgggatcg cctgcatcca cgacatccat gtgcccgtca acccctaacc agcgctgcgc
    10561 attagaatca ccaatcgtca aaactaaatt gtcgcgtccc ggcgcataac tgatacgttc
    10621 acgcttaatc aaccctgcgc ttagttccgg ggccaaaaag gcttcgatca agtccgccac
    10681 ttggccttct tttgctgcca cactggggat tctaaccatc gcctgcaata gatcagtaac
    10741 ttgttgttcc tcgtctgtca aactaccgcc tccactttta aaatacatca tcttaacgat
    10801 ccaaatcgcc accatgactg agttcatcta gtcacatcag gtgctatcaa caccattatt
    10861 ccgaacacgc aacccagtct tttaacgcag ccttattttc ttctaaagcg caacaatgcc
    10921 tgacctaaga ttggggtgac aatcccgccg agcaccgcct ctgccaccgc attaatggcc
    10981 aaggcagtaa tcaacagcca acctaaattc gttgcattgg cccctggaac gatttgcgcg
    11041 gctttgctgg caaacaacaa ccaggtaaag ccgatcacca gcaatgtgtt ggttaaagcg
    11101 cctgcaaccc cggcgatgac cattttaata gtttgagcca gcgtactctg gtggcgtttg
    11161 aataattgat gaaaaacaaa agctgcaacc aaaccaacca tgactcgcgg caccaacgcg
    11221 ataattggat tgcgaaaaag cagtaaagtt accgggtcag ccgctgatgt ataagcgcga
    11281 atcagactcg ttaatcccca taataagcca aggctggcac ctccgccata gcccaatacg
    11341 atcccgccaa tgatgacggt caagtgaata gtcgaaatag ccggccaagc gggaaaaatc
    11401 tgaacataac caaccattgg aatataggct tgcaaaataa tcaaagctcc caaaatacca
    11461 atgatcgcaa tgttataagc ttttccgcga cgtgtcatgc tgacacctcc taatcgttta
    11521 tagctaattt tatcaaatta tagacgttta cgtttgttta tattgtgttt tctgctgttg
    11581 ctgattcaat caaagcagac cattgccttc aggtatggct catgttgggg caatagtccc
    11641 tgatttgaca atattgcttg cggtcgccag tgttagctac cgctgaggcc gcttgtgttc
    11701 tggcttacgc ccttttaacg cgcttaccgg cgcagaagtc tgcgtgtaag gacctcagtc
    11761 gcaatggcca aagcccggcc atcacgcctg aggccacttg tgttctagtt tacgcccata
    11821 acgcgctcac cggcgcagaa acctgcgtgt aagtacctta agcgtaatgg cccaagcccg
    11881 gccattacgc ttaaggccac ttacactccg gtttctaagc gcgccggttc gcgcttagta
    11941 aatttctatt gactttaatc tcacgttttc ctataatatt tcttgtgctt aattagtcat
    12001 gcgggcatgg cggaattggt agacgcgcaa gattaaggat cttgtgagca tttttgctca
    12061 tggaagttcg agtcttcttg cccgcatcat agcaagatcc gatcaacaag gtattactgt
    12121 tgatcggatc ttttttattt tatacctgat catggcccgg cttgaaaaat attaagcctc
    12181 tgaaaggagt cccattcgat gcttcgtgaa gcccaatttg tcgatctgcc ggcgattgtt
    12241 catctttatc agcagcttac tcaagagatg gctgcattgg cgccggatac ttaccggccc
    12301 ttaaccaccg acaatcggca gtattttgct gattacttgc agaatgatct ggctcgccta
    12361 ttcgtcacgg aaagccaagg cacacttacc ggctttgcat tggtcgtttt agctcgaacc
    12421 ggggacagcc ccgaattcgt tccacaacac tttgcgcagt tgattgactt gtttgtcacg
    12481 ccggatcatc gtcatcacgg cctagccaaa accctcatga cagcggtcga ggcattcgct
    12541 gccagtcatc aagcctcttt tattcaactg aacgtcctca gcggtaatca aaccgcacga
    12601 gaagtctatg cccgcgccgg gtttcagcca gtcaatttaa tcctgcaaaa gccgctcaat
    12661 tagttatttc gtgttgcctg cagtcgtaat ttgccacggc agacaccgca cgcgtaccgg
    12721 ttgacattaa tccgtcggcg ccgaacaaat tgccggccac accttgtaca ttgataaaca
    12781 tagtgtcggc cgttcatcgg caatgacgga gcaaaacgcg agccgccaac tgctgccagt
    12841 aactgtttga agtcatgatc gcgatgttga tagccgcgat gctgggcgaa caaatggtag
    12901 tgcaccaatt catgcttgat gatgccatcc gtgacatcag atggataaag cgcaaaaatt
    12961 ttggggttaa aatccagatt catcgtcgca ggataaaacc ggccgccagt agttcgcaat
    13021 cgcgcattaa acacggcttg gtggttgaac ggttggtgaa atgcgctcat agaaatggct
    13081 tccacacgtg cttgtaattc ttggtttgtc attgtctcat cgttacctcc gagccaatag
    13141 tgtacatcag cacgtcacca attgcaccat ttgtatcagg ctactttgcg agactatccg
    13201 atacctgttg agtatgttca tctcactatt catcagacta caaaaaggaa cggttcagac
    13261 gtccacctga accgttcctt ttttctaacc atgaaacttg cgcattgacc aagcaaatga
    13321 gccatcacaa gcaaatttgc ctaccttttt cacactcgct taattgaaaa aggctaagac
    13381 atcggcacgc ttcaatgctg cttttcgttt ttgatcgaag tctgccacaa tctggccggc
    13441 atctagcaca atgagccggt tgccatagcg taacgcgtct tcaacttgat gggtgatcat
    13501 cagacaggtt aactgttgct ccgaaacgat cgcgttcgtt aacgccataa ttgcctgact
    13561 ggtgtgggga tctaaggctg ctgtgtgttc atcaagcaac agtaaatccg gtttgcgcat
    13621 ggtggccatt aacaagctca aggcctgccg ttgtccacct gaaagctgct ccgttggctt
    13681 atcaagcgcc tcagccagac cattaccggt ttttgcggcc aaagccttta gctgggcttt
    13741 ttgtgcattc aacccccggg aacgtaaccc taggcgctga ccacgatggc tggctagtaa
    13801 taaattctca gcaaccgtca ttcgcggggc ggttcccatt ttcggatcct ggaaaactct
    13861 ggcaatgtgt cgagcacgtt gctcaggacg gcgcccgttg agtgtttggc cagccaaagt
    13921 gaccgtgccg ccgctaactg gtagatcacc ggtaatcgca ttgaataagg tcgatttacc
    13981 ggcaccatta tgacccaaaa cggtgacgaa ttcacctgtc ttaaccgtca gcgtcacatc
    14041 ttgcaacaag gtcttgactt gagttgcaac tggcacatta accgtcacgt gatccaactt
    14101 taattcagcc atggatctgc acccctttct gcaacacacg tcgtaatcgt aattgatgat
    14161 caatttgcgg caccatgatg gcaatggcta acacgaccgc cgagatcagt ttcaaatcat
    14221 cggcattgaa gcctagcgcc aagacaacca gcaagacaaa gcggtaaata atgctcccta
    14281 agatgactgc caccaaccgc tgcgacaaag tcaactcacc gaaaacaact tcgccgatga
    14341 taatagcagc taacccgata acaatgatcc cgatgcccat gttcacgtcc gcatagccat
    14401 tattttgagc gagcaaccca cctgcaagcc caaccagccc attgccaacc attaagccca
    14461 gaaccatttg atgatcagga ttaatcccca gactccgcgc catattcgga ttatcacccg
    14521 ccgcaatgaa cccttgacct aactgggtgt tcagaaataa catcaacaat ccgacgacga
    14581 tgacgacaac aattaaacca acaaccacgc tattaaagta aggcggcaag tcttttaaga
    14641 acgatccttg gaaaagatta gcctgatgta gcaaagataa attggcccgt cccataatcc
    14701 gtaaattaat cgagaataag ccggtcatga ccaggatccc ggcaagtagc accggaattc
    14761 ggcctttggt agttaacaac cccgtcacca gcccggcaag catccctgct accgttgcga
    14821 gcaaggttgc gataatcggg gaaataccgt gagtaatcgc actgacggcc actgctgcgc
    14881 caaagggaaa tgttccttca accgtcatat ctggaaagtc caacacccga aatgttaaaa
    14941 agagacctag tccgattaaa ccgtataaca atccttgccc aattgcagaa acccctaaac
    15001 tcatttgatc accgttcctt tcgcgtctgc ctgtttcact aacgaactcg gcaatgttat
    15061 ccccaactgc tgcgcttgtt tttcatttaa aataagtcgg ccggtttttt caaagtggat
    15121 cggcgtcgtg gccggtttgg ctttgccttt taaaacatcc gccagcatat gcccggtttc
    15181 aacacctaaa tcaaattgat taagtccgat cgttgccacc ccgccttgtt taaccatggt
    15241 atccacagtt ggaaaaatcg gaacctttcg tgcgttagcc gctgccacta aagtttgcat
    15301 ggcgctcgcc accgtattat cagtcggcac aaacaccgcg tccacctggc ttaccatttg
    15361 cgtcgccact tggttaagat cgttggtcga gctaatcgca taccgtttaa ccgtgaaccc
    15421 ttctttgggg cctagtttag ccaccatctt ggcttgggtt tgtgcggaat catcactgga
    15481 agtcgcaatg acgccaagtg ttttcgcatc aggcatgatc tgccggataa gtttcaattg
    15541 agctgcaatc ggggcttgat cggaaacccc ggtaatattg ccgcctggtt ttttaacatt
    15601 tttaaccaac tttgctgcga ctggatccgt aattgccccc aagatgatcg gcgtcttttg
    15661 attcacattg gctagtgctt gagctgcagg cgtagcaata ccgactgttg cagcggcatg
    15721 ttcctcagta aagcgttctg acattgactt cagattgctc tgatcatttt ccgcgttttg
    15781 aaaatcaatc ttgatattct tgcccgccac gtagccttta tctttcaatc cggcgataat
    15841 gcccttatga atcgcatcaa gcgccggatg ggttgtcagc tgcaaaatgc cgacagtcgg
    15901 ctttgtctgc gtctgtt
//
