LOCUS       c00069_gnlPro..        13320 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OKPMNBIN_69.
ACCESSION   c00069_gnlPro..
VERSION     c00069_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 04:29:43
            Original ID  :: gnl|Prokka|OKPMNBIN_69
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 198
            Orig. end    :: 13518
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13320
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[10198:13371]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13173
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13320
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13320
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(27..1241)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 100.5; E-value: 3.1e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg69_1"
                     /sec_met_domain="MFS_1 (E-value: 5.4e-32, bitscore: 100.5,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRQAKIGWQGQTAAFLLSQNLFVFGTSTVFFAVLWDIALKTSSGA
                     WMTYVSLATALPAILISLSAGVLADRYNRKWLIVISAVGVTVLTLAVAYVFAFVTQELW
                     LLLVIAVIRSFGNGLENPAANALLPQLVPEKQLTQVNGYNQMLMAAMLVISPLLAGYTL
                     SDLGIFWIFVIDALTAVLAVLCLGIVHVPTPVTNPDQATKQKNGIVAGLRYVGHTPVLL
                     AFMFFTGLAFILIAPSSQLSTLYVNRTFGSEVWHLTFNEWSWTIGAGLGGLFIARHKKF
                     RDQLGLIALGFAGSGIAFAEMGLPQPFMTYLLFMLVSGIFYPLIQAGQTIYLQENVPAD
                     KLGRVFSLWAILSTGIYPLAMLGYGPLADRVPIGWIFIVTGLLLIVVAYGFWRRLKHLN
                     GSSNK"
     CDS             1339..2034
                     /locus_tag="ctg69_2"
                     /transl_table=11
                     /translation="MPQKIFIVEDDDVIAKTIGNYLNRWAFTVELVQKFDQVDAEIRAA
                     APDLVIMDISLPYFNGFHWLSELRKHSKVPVIFLTSSGDDMNLVMAMNLGADDFLAKPI
                     ELPVLLAKIQGMLRRTYQYQQTDTNLSHGEFTLVPTDNQLRSPTQVIDLTPTETKLLSL
                     LFGADGEVVTREAMIEKLWEGDEFIDRNALAVNMNRLRKKVAPVGLNQLIETVKGKGYR
                     LANKEGGHD"
     CDS             2027..2986
                     /locus_tag="ctg69_3"
                     /transl_table=11
                     /translation="MIKAFLRARWMVWLSLLILLVASLLANWLINASLEVALNSWFFAL
                     IPLLVIGGCDFWRFRREWSQLQGDVTLLAADQISDPLGQVYFQKIQMLQQTLRQNHDTY
                     RDQEQETVDTLQLWTHQIKTPLTALDLLLQVEPVNASDARLEVGKINRYLTVMLNYLKL
                     TTLNTDLVLTELPLKPLVNETVRDLAKLFIAKDLTVTVETLPTVVSDSQWLRFIFEQLL
                     TNAIKYTPHGSIRIYAKGDAVLVADTGIGILPEDLPRIFEQGYSGYNGRANQKASGLGL
                     FLSRQIAQKLGLTLTVTSKVGVGSTFAIHFPQTRWLAE"
     CDS             3080..3850
                     /locus_tag="ctg69_4"
                     /transl_table=11
                     /translation="MSTLLKLKNVEKTYTSRGAQPVQALVNISFSVESGEFVAIMGESG
                     SGKSTLLNLIATLDDPTGGEISLNGQDLRKVKEGARAKFRREHLGFIFQDFDLLDTFNV
                     QDNIFLPLVLAKKPLEIMKNRLTQLAPRLGITDLLKKYPYELSGGQQQRVAAARAMITD
                     PEILLADEPTGALDSRTSSELLDLLTDVNADSKQTILMVTHSAVAASHSQRVLFIRDGQ
                     IFHQLYRGELQQPEFLTRISETMTAMLTKEGEAQ"
     CDS             3847..5832
                     /locus_tag="ctg69_5"
                     /transl_table=11
                     /translation="MKFYFKLAATNLKADRRLFVPFVITTSFLMAINLIMLNAYTSSDV
                     LFRQFGQAAGKSLFSFGSMTTAIISVILIIYANNFLRKQRIRQLGLYNIIGFGKRELSK
                     MMATEKLLLLLTTLLCGGILGTVLSRLSYLTLAKMLHVNHNLDFGLSQTAFSIAGLITI
                     GLFIVLMLVDEFWLLRKHPIELVREQNAGEREPKTKWLTLIVSIASLAAGYTIAVTVKN
                     PLQAMSLFFFAVVLVIVGTYGLFTSGSVFVLKWLRHRKNYYYKPKHFINVSNLLYRMQQ
                     NGAGLASIAILVTMTLITLATTATLFFGIHEIVNSQTPVDLAYSINPKRPDAANQLRTL
                     AKTHHVKIHSMRTFNGPSSTLALLEKNKLDSQANFNGPFSFNNARSVQLMTVENYNRYT
                     GKHVTLNNHEVLIYASNHYEPATLRIGKQTYHVAKQVTSFPNAPKTFIPNLFVALPSDV
                     QLLTALHALYPKRSMALLKADVTTNQDVTLSGSHANQVKLYHAVVKRGIALPESVQSRA
                     ANYDDTASMMSSFLFLGVVFGVTFILATLLILYYKQLAEGYADARRYTILQRVGLSLRE
                     VRATINSQLLTLFYLPLIVAAIHVGFALPFVQRIMMLFGLPDWQFFLTVSLITLAIFAV
                     IYVLMYRLTGNVYYRIVSRRQPSSRG"
     CDS             complement(6009..6749)
                     /locus_tag="ctg69_6"
                     /transl_table=11
                     /translation="MRTVSLYFYRNVWNKVKLKTHAETTTYRNHKLQEMLFVDGEDARF
                     LQWLDQQYAQQLPSKPRAYFEATKERNLAIIALLFGSGVRVSELVNMNLEDLNMDRHTV
                     QVVRKGNFQDRVNFADWIDPYLTAYLKSRTAMIGQQKPTSPLFVTQIGQMVNRIRQNTI
                     EAFFKRYTTAYGRPSTPHKARHTLGTNIYTVTKDVQQVADQLGQTTTSATDLYINLSDK
                     SGKAALREVSETAAKALDQHPQQP"
     CDS             complement(6706..7122)
                     /locus_tag="ctg69_7"
                     /transl_table=11
                     /translation="LSTQNYPKLIQAMLPSLPDYIQDYYHSQKAIPIADSTLYQYLHFY
                     QEFLHWLISSRVTDAISPQNVPLETLERLSLRDAQAFVAYLLERPSKTHPNKRMTRRSV
                     ALRLVGIKALYRFLTEESEPNADGEPLFLPQCLE"
     CDS             complement(7950..8882)
                     /locus_tag="ctg69_8"
                     /transl_table=11
                     /translation="MTTLIFGHQNPDTDAITSAMSWAEFQKQAGNTDVEAVALGEPNDE
                     TKFVLDHFKVAAPRVIKTAANETGHVMLVDHNEFQQSVADIEDVQIDSVVDHHRIANFH
                     TASPLYYRAEPVGSTNTVIFELFQEHGYEISPTLAGLMASGLISDTLLLKSPTATDKDK
                     KILPEMAKIAGIDLQSYGLAMLKAGTNLAAKSDMDIIEGDAKSFTMGGKSIRIGQVNTV
                     DLDDIYARQDELVAAMTKEAQAKGYDDFLLIATDILNSNSTGFAVGADRDKVAAAFNEK
                     FDANDRLALPGVVSRKKQVVPPMQGAFEG"
     CDS             complement(8912..9880)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     55.5; E-value: 1.4e-17)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg69_9"
                     /sec_met_domain="LysR_substrate (E-value: 1.9e-27,
                     bitscore: 85.5, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.4e-18, bitscore: 55.5,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKQERIFSSKTLTYFLQLAETMNYTQSAQLLGITQPALTQQIK
                     KLERTVGAPLFYSVGKKLHLSDAGRTMLKATHEIYEILNQTTDEIQQSTSATVGKINIG
                     LLSSIEDSAFNAFIAHYYDLNPEVEITLRMMTRHEIWEALENNQIDLAIMNLPDETIKN
                     WKPYASKKILDEQLLFLHHDNSLANRKRLHFKDTLAEPWVTYPDDYFLGQLLHEAYKNQ
                     MVDFPHVVAHFTTPYQLTQFVNHTGVNTALPTSFVAAHADQIKAHAVAFEPAIRFETSF
                     VYRKEKADIPRIANFFKTFDAHLSEKDYLSRVSENSGKIER"
     CDS             complement(10001..10852)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 66.6;
                     E-value: 9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_10"
                     /sec_met_domain="Radical_SAM (E-value: 5.2e-27, bitscore:
                     84.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLIDQSQSPLNILEQVGQDHEGPIKGYVHSVESFGSVDGPGIRF
                     VVFMQGCRMRCQYCHNPDTWNIGVGEEMTADQILADAQRYKAFWGEQGGITCSGGESLV
                     QIDFILELFTKAKELGISTCLDTSGGPFTRDQPWFGQFEKLMAVTDISLVDIKHIDSAE
                     HKKLTGFPNENILDMVQYMSDHGDDMWIRHVLVPERTDFDPYLKRLGDYIATLDKRVVQ
                     KVEILPYHTLGVKKYHELGITYPLEGIEPPSADRVKNAENLLHVEDYTGWQSWRPQPAN
                     KQ"
     CDS             complement(10990..13173)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_11"
                     /sec_met_domain="Gly_radical (E-value: 4.1e-42, bitscore:
                     132.7, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 4e-244, bitscore:
                     800.9, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRDFIEHNLNQYDGDESFLAGPTEATTVLNNQVLNLKKQERANGG
                     VLDADNNIPSTITSHGPGYLNKDLEKIVGVQTDKPFKRAFMPFGGIRMAEDALKSYGFE
                     TDANEHKIFTEYRKTHNQGVFDAYTPEMRKARHYKIVTGLPDAYGRGRIVSDFPRIAIY
                     GIDRLMAEKFNDYNLTGDGEMTDDVIKLREEINEQYRALNDMKKMAKEYGYDISRPAAN
                     AQEAVQWIYFGYLAAVKTQNGAAMSVGRIDTVIDAYIQRDMRLGKLNEEQAQELIDHLV
                     MKLRMVRFIRTEEYNSLFSGDPIWATLSLAGMGNDGRHHVTKTAFRFLKTLDNMGAAPE
                     PNITLLWSERLPEGFKRYATEVSIQSSTIQYENDDLMRNEWGTDYYGIACCVSAQPIAD
                     GVQYFGARANLAKTVLYAINGGKDEIQEAQVGPEYEPITSDYIDYDEFMKKFDKMMDWL
                     ADVYVNALNVIHYMHDKYYYEAAQLALKDTRLNRTFATGISGLSHAVDSISAIKYGHVK
                     AIRDENGVAIDFVADNDDYPRYGNNDDRADNIAKWLVKTFYNKMNTHHLYRGAKLSTSV
                     LTITSNVVYGKNTGTTPNGRQKGEPFSPGANPAYGAEKNGALASLMSTAKIPYHYATDG
                     ISNTFGVTPNTLGHDDETRKDTLVHMVDGYMENSGMHLNINVFNKETLIDAQKHPEEYP
                     TLTVRVSGYCVYFADLTKEQQDDVIARTFFDEM"
ORIGIN
        1 tagcgttctt ttttcaataa tagatgctac ttatttgatg acccattcag atgcttaagc
       61 cgccgccaga acccataagc gacaacgatt aacaacaaac cggtcacaat gaaaatccat
      121 ccgatcggca cacgatctgc cagtggtccg taacccaaca tggctaacgg ataaatcccg
      181 gtcgacaaaa tcgcccacag cgaaaagacg cgcccaagtt tatccgcggg cacattttcc
      241 tgcaggtaga tagtttgccc ggcctgaatc agcggataaa agatcccgga aaccaacata
      301 aatagcaagt aagtcataaa tggctgcggc aagcccattt cggcaaatgc aattccgctg
      361 cccgcaaaac caagcgcaat caaaccaagc tgatcccgaa actttttgtg ccgcgcaatg
      421 aacaaaccgc ctaacccggc accaattgtc catgaccact cgttaaacgt cagatgccag
      481 acctccgaac cgaatgtacg attgacatat aatgtcgata attgggaaga aggggcaatt
      541 aaaataaacg ccagtccggt gaagaacata aatgccagca ataccggcgt gtggcccacg
      601 tagcgcaaac cggcaacaat gccatttttc tgcttggttg cttgatccgg attggtgacc
      661 ggtgttggca cgtgaacaat ccctaagcac aacactgcca gtaccgctgt gagcgcatcg
      721 atgacaaaga tccaaaaaat ccccagatcg ctcaaagtat acccggccag cagcggggaa
      781 atcacgagca tagcggccat caacatctga ttatacccat tcacctgcgt caattgcttt
      841 tccggtacca actgcggcaa taacgcgtta gccgccggat tctccagacc attaccaaaa
      901 ctgcgaatca ccgcgatgac gagcaacaac catagctctt gcgtcacaaa cgcaaacaca
      961 taagctactg cgagggtcaa aacagtcaca ccgactgcag aaatcacaat cagccattta
     1021 cgattgtagc gatccgccaa gacgcctgct gaaagcgaaa ttaaaatagc tggcagggcg
     1081 gttgctaacg aaacataggt catccacgcg ccggaagagg tttttagcgc aatatcccag
     1141 agcaccgcaa aaaagacggt ggacgttcca aaaacaaata aattttgact taagagaaag
     1201 gcggcagttt gcccctgcca cccaattttg gcttgtctca cttttaacac ctgaaatcag
     1261 ttaaaataga agctgacttt agtttaaagc aattgactta aaaagcccac gaatcaccac
     1321 gaggggagca taacaaacat gccgcaaaag atttttattg ttgaagacga tgacgtgatt
     1381 gcaaagacaa ttggtaacta ccttaatcgg tgggcattta cggttgaatt ggtccaaaaa
     1441 ttcgatcagg tggacgcaga aatccgtgcc gccgcaccgg atctggtgat tatggatatt
     1501 agcctaccgt attttaatgg cttccactgg ctgagcgaat tgcgcaaaca tagcaaggtc
     1561 ccggttatct tcctgaccag ttccggggat gatatgaatc tggtgatggc gatgaatctc
     1621 ggtgcggacg actttttagc taagccgatc gagctaccgg ttttattggc gaagattcag
     1681 gggatgttgc ggcgaaccta ccaataccag caaaccgata ccaatttaag tcacggtgag
     1741 tttacactgg tcccgaccga caaccaacta cgctcgccga ctcaagtgat cgacctcacc
     1801 ccgacagaaa ccaagttatt aagcctgtta tttggtgccg atggtgaagt ggttactcga
     1861 gaagcgatga tcgagaagtt atgggaaggc gatgagttca ttgaccgcaa cgccttggca
     1921 gtgaacatga atcggctacg caaaaaagtc gccccggtag gactcaacca actgatcgaa
     1981 accgtcaaag gaaaaggtta tcgtttagca aacaaggagg gcggccatga ttaaagcttt
     2041 tttgcgcgcc cgctggatgg tttggctgag tttgctcatc ttactggttg ccagtctgtt
     2101 agcaaactgg ctgattaacg cttcgcttga agtcgcgtta aacagctggt ttttcgcact
     2161 gattccgtta cttgtgatcg gcggctgcga tttttggcgg tttcgccgcg aatggtcgca
     2221 gctccaaggc gatgttacac tgcttgcggc tgatcaaatt tccgatccgc ttgggcaggt
     2281 ttattttcaa aaaatccaaa tgctgcaaca gaccttacgt caaaatcatg acacgtatcg
     2341 tgatcaggaa caagaaacgg tcgatacctt gcaactgtgg acccatcaaa ttaaaacacc
     2401 gctgactgca ctggatctct tattacaggt tgaacctgtc aatgccagcg atgcgcggct
     2461 tgaagttggt aaaatcaacc gttatctaac cgtgatgctg aattacctca aactgaccac
     2521 actgaatacg gatttggtgt taaccgaatt accactaaaa ccgcttgtta acgaaaccgt
     2581 gcgggattta gcgaaactgt ttattgccaa agacttaacc gtcacggtag aaactttgcc
     2641 cactgtggtg agtgatagtc agtggctgcg atttattttc gagcaattac taaccaatgc
     2701 catcaaatat accccgcatg ggagcatccg gatttatgcc aagggcgatg ccgtgctggt
     2761 ggctgacacc ggtatcggta tcctgccaga agatctaccg cggatttttg aacaaggcta
     2821 ttctggatac aacggtcgcg ccaatcaaaa ggcaagtggc ttaggcctgt ttttaagccg
     2881 gcaaattgcc caaaagctag ggttaaccct gaccgttaca tcaaaagtcg gtgtcggcag
     2941 cacctttgcc attcacttcc cgcaaacgcg ctggctggcc gagtaagcca ccttaccagc
     3001 ttgtaagcaa cgcacgtcga ctgtaagtag tttttcggca gtttcccttt taagctgata
     3061 aatgaaaggg gcggatctta tgtcaacatt attaaagtta aaaaatgtcg aaaagactta
     3121 taccagtcgc ggtgcccaac cggtacaggc actcgtgaac atcagttttt ccgttgaatc
     3181 aggagaattt gtcgcgatta tgggggaatc cggttcaggc aaaagtacct tactgaactt
     3241 aatcgccacg cttgatgatc ctaccggcgg cgaaatcagc cttaacggac aggacctgcg
     3301 caaagtcaaa gaaggcgcac gggctaaatt tcggcgggaa catctcgggt ttatttttca
     3361 ggattttgac ttgcttgaca cctttaacgt tcaggacaac attttcctgc cattagtctt
     3421 agccaagaaa ccgcttgaaa tcatgaaaaa tcggctcacc caactggcgc cgcgtctagg
     3481 tatcaccgat ttattgaaaa aatacccata tgagctttcc ggtggccaac agcaacgtgt
     3541 ggccgctgcc cgggcgatga tcaccgatcc ggaaatccta ctggcagacg aacccaccgg
     3601 cgcacttgat tctagaactt ccagtgagct gttggacttg ctaaccgatg tcaatgccga
     3661 cagtaagcag acaatcctca tggtgacgca cagtgcggtt gcggccagtc atagccagcg
     3721 cgttttgttt attcgcgatg gtcagatttt ccatcagctg tatcgcggtg aattacagca
     3781 acccgaattt ttgacccgaa tcagcgaaac catgaccgca atgctgacga aggaaggcga
     3841 ggcgcaatga aattctattt caaattagcc gccaccaacc ttaaagccga tcgccgttta
     3901 tttgtgccat ttgttatcac cactagcttt ttgatggcca tcaatttgat catgctaaac
     3961 gcctacacga gcagtgatgt attgttccgc cagttcggac aggcagctgg caaatcactg
     4021 ttttcatttg gctcaatgac gaccgcaatc atttccgtca tcttaatcat ctacgccaac
     4081 aactttttgc gtaaacagcg tatccgccag ttggggctct acaacatcat cggctttggc
     4141 aaacgtgaat taagcaaaat gatggccacg gaaaagctgc tgctattgtt gacaacctta
     4201 ttgtgcggcg gaattttggg aaccgtgctg tcacgcctta gctatctcac tttggccaaa
     4261 atgctgcatg tcaatcacaa tctcgatttt ggcttgagtc aaactgcctt cagcattgcc
     4321 gggttgatca cgattggctt gttcattgtt ttaatgttgg ttgacgagtt ctggctattg
     4381 cgcaaacatc ccatcgaact cgtacgcgaa caaaacgctg gggaacggga acctaaaacc
     4441 aagtggctaa ctttgattgt cagcattgcg agtctggctg ccggttatac gattgcggtc
     4501 accgtcaaga atccgcttca agcgatgagc ttgtttttct ttgcggtcgt ccttgtcatt
     4561 gtcgggactt acggtctctt cacgtccggc tcggtatttg tcttgaaatg gctgcgtcac
     4621 cgcaagaact actattacaa gcctaaacat tttatcaacg tctcgaatct gctttaccgg
     4681 atgcagcaaa acggcgcagg gttggcttcg attgctattt tagtcaccat gacgctgatt
     4741 acacttgcaa ccaccgcaac gttattcttt ggcattcatg agattgtcaa ctcgcaaacc
     4801 ccggttgatt tagcatactc aatcaacccc aagcggccgg atgcagcgaa ccaactacgg
     4861 acactggcta aaacacatca cgtcaaaatc cactcgatgc gaacctttaa cggaccctca
     4921 agtacgcttg ctttattaga aaaaaacaag ttagattctc aagctaactt taacggcccg
     4981 tttagcttca ataatgcccg ttcggttcag ctgatgaccg tcgaaaatta taaccgctat
     5041 actggcaagc atgtgacact taacaatcat gaagttttaa tctatgcctc caatcattac
     5101 gaacccgcca cgttgcgtat tggcaaacag acttaccacg tcgccaaaca agtcaccagt
     5161 tttccaaatg cgcctaaaac gtttattcct aacttgtttg ttgcgctccc atctgatgtc
     5221 caactattaa ccgctttaca cgcgctttat ccaaaaaggt caatggcact gctcaaagcc
     5281 gacgtgacca ctaatcaaga cgtaacatta agcggcagtc acgccaatca ggtcaagctt
     5341 tatcatgcag tcgtcaaaag agggattgca ttaccggaat cggttcaatc gcgagccgct
     5401 aattacgatg atactgccag catgatgagc agtttcctat tccttggggt tgtctttggg
     5461 gtgaccttca tcctggcaac cttgctgatt ctttactaca agcagttggc agaaggctac
     5521 gcggatgcac gccgctatac catcttacaa cgcgtcggcc tgagccttcg ggaagttcgc
     5581 gctaccatta atagtcagct actcacactg ttttacctgc ctttgatcgt cgctgccatc
     5641 cacgtgggct ttgcattgcc ctttgtccaa cgtattatga tgctattcgg cctgccggat
     5701 tggcaattct tcttaaccgt ttcgttaatc acgcttgcaa tttttgcggt catctacgtg
     5761 ctgatgtacc gtttgaccgg caacgtttat tatcgaattg tttcccgccg tcagccatcc
     5821 agtcgtgggt gagggcggtc tgacgcatag tataaaaaaa gctgcctgat cgcaagccat
     5881 caaaggcgat caggcagctt ttttctatgt caaccagcat caaaaaatgt cgccactgtt
     5941 atctcactga atactgtgac gttaattagc gccgcaacat gacttaacca gacaactaac
     6001 cgccgacatt atggttgctg gggatgttga tccaaggctt tggcggcagt ttccgaaact
     6061 tcgcgtaagg ccgcttttcc acttttatcg ctgagattga tgtacagatc cgtcgcgctg
     6121 gtcgtcgttt gtccgagttg atcggcaact tgctgcacat ccttggtgac ggtataaata
     6181 ttggttccca aggtatggcg tgctttatgg ggtgttgatg ggcggccata agcggttgta
     6241 tagcgtttga agaatgcttc aatcgtattt tggcgaatgc ggtttaccat ttggccgatt
     6301 tgcgtcacaa atagcggaga agtaggcttc tgctgaccaa tcatcgcggt tcgggacttc
     6361 aagtaagccg ttaaataagg atcaatccag tcagcaaagt taacgcgatc ctgaaaatta
     6421 cctttacgca ccacctgcac agtatgacga tccatattga gatcttccaa attcatattg
     6481 accaattcac taacccgcac gccggagcca aacagcagcg caatgatcgc caaatttcgt
     6541 tccttcgtcg cctcaaaata agcacgcggt ttcgatggca gctgctgagc atattgctga
     6601 tccagccact gtaaaaagcg cgcatcttcg ccatccacaa acaacatttc ctgcagttta
     6661 tgattacggt aagtcgtcgt ctctgcatgg gtcttaagtt tcaccttatt ccaaacattg
     6721 cggtaaaaat aaaggctcac cgtccgcatt tggttcgctt tcttcggtta agaaccgata
     6781 aagggccttg atcccgacca gtcgtaacgc cacactgcgc cgcgtcatac gtttattcgg
     6841 atgggttttt gacggccgct caagtaaata cgccacaaac gcctgcgcat cacgcaagga
     6901 aagccgctct aaagtttcca aaggcacatt ctgtggcgaa atggcgtccg tgacccgact
     6961 ggagataagc caatgcagaa attcctggta aaagtgcagg tactggtaaa gggtagaatc
     7021 cgcgatggga attgcttttt ggctgtgata gtaatcctga atatagtccg gcagggaagg
     7081 tagcatggct tgtattaatt taggatagtt ctgtgtcgac aaataaagtc acctcgaaca
     7141 tatgttttct tttggataat ttcagtatac gcgaaaaaac cagtgcgtgg cgagggataa
     7201 tgacgaaaat atcggtaatt cgcaacgata tgcgccgaaa aaagcaccag tgtagaactg
     7261 aataaagttt tagtattatc caaaggtaaa tgggcttcta atcatcaagc cagctaaatc
     7321 accaaatttg ttgatctgtc atttgacact aaacttagtt gcatttcaaa tttgaattta
     7381 ctgcacgatc aggaccatct gtgctgatgt cctgattcca cggcgccgct ttagcaacag
     7441 tttaaccaat taaccaacga ttcattggct gcaatcaaat caattttcgt attttgatcc
     7501 agaattcagc tgacagcaac acttgcgact tgaatgctgt ttatgactca aaatgatact
     7561 ttctacaaat ctgctttgat taatgctgaa tttacatata tttagcaacg actggtcatt
     7621 ttcaaaccag aaaaaacaaa taaagcgcac cgctcacatc cgtacaattg atttgcttct
     7681 ctcaaaagtt tttgagctgt ctgtcaggtg aggggacttg catcaatcgt tttgccattt
     7741 gaacaccaaa taagtcacgt caaagtcaac gactcaaaat ctccattcta gtttacataa
     7801 tatatattat acgaagtagt tatgaggctg cgttttttgc acctcgtttt aaatttgaac
     7861 tatccttttt gttcatccaa gtttttgagc acaaaaaaat cgcaaccaca aacggctgcg
     7921 atttataaaa ccaattatta agttcaaaat taaccttcaa acgcaccttg cattggcggt
     7981 acgacctgct tcttacgtga aaccacgcca ggcagtgcca accggtcatt tgcatcaaac
     8041 ttttcgttga atgctgcggc cactttgtca cgatctgcgc caacagcaaa gcccgttgaa
     8101 ttgctgttca gaatatcggt tgcaattaac aggaagtcat catagccctt cgcctgtgct
     8161 tctttggtca tagcggccac caattcatcc tgacgcgcat aaatatcatc aagatcaact
     8221 gtattcactt gtccaatacg gatagactta ccgcccatcg taaagctctt cgcatcgcct
     8281 tcaatgatat ccatatccga cttggcagct agattggtgc ccgccttcaa catagccaag
     8341 ccatatgatt gcaggtcaat gccagcgatt ttagccattt ccggcaagat ctttttgtcc
     8401 ttgtcggttg cagtcggtga cttcagaagc agggtatccg aaatcaagcc agaagccatt
     8461 aagcctgcca gtgttggtga aatttcatag ccgtgttcct ggaacaactc gaaaatcacc
     8521 gtgttggtac tgcccactgg ttctgcccgg taatatagtg gtgacgccgt atggaagttg
     8581 gcaatgcggt ggtgatcaac cactgaatcg atttgcacgt cttcgatatc agcaacgctt
     8641 tgctggaatt cgttatgatc aaccaacatt acgtgcccgg tttcatttgc ggctgtctta
     8701 atgacccgcg gcgcagcaac cttaaaatga tccaatacaa acttggtttc atcgtttggt
     8761 tcaccgagtg ctactgcttc aacatcggta ttacctgctt gcttctgaaa ttcagcccaa
     8821 ctcatggcgc ttgtaatcgc gtctgtatca gggttttgat gtccaaaaat caaagtcgtc
     8881 atgttatctg atcgctcctc agctgaatag tttaccgttc aattttacca ctgttttcgc
     8941 tgacccgcga tagataatct ttctcggata aatgtgcgtc aaacgtctta aagaagttgg
     9001 caatccgcgg aatatcggct ttttccttgc gatacacaaa cgaggtctca aagcgaatcg
     9061 ctggttcaaa ggcaacggca tgcgccttga tttgatcagc atgagcggca acaaaactgg
     9121 ttggtaacgc ggtgttaaca ccggtatggt tgacaaactg agttaactga tatggcgtgg
     9181 taaaatgcgc cacaacatgc ggaaaatcaa ccatctgatt cttatacgcc tcatgcaaca
     9241 actgacccag gaaatagtcg tctggataag ttacccacgg ctcagccagc gtatctttaa
     9301 aatgcaggcg tttgcgatta gccaaggaat tatcatgatg caggaacaat aactgttcat
     9361 caagaatctt cttgcttgca tacggcttcc agttcttaat cgtctcatca ggcagattca
     9421 tgatggccaa atcaatctga ttgttctcca acgcttccca gatctcatga cgtgtcatca
     9481 ttcgtagcgt gatttcgact tcaggattaa ggtcgtaata atgcgcgata aaagcattaa
     9541 acgcactgtc ttcaattgaa cttaacaagc caatattaat cttgccgact gtggcactgg
     9601 tgctttgctg aatctcgtca gtcgtctggt tcaaaatttc ataaatctcg tgtgtcgcct
     9661 tcaacatcgt gcgaccggca tcggataaat gcaacttctt accaacggaa taaaacaatg
     9721 gtgcccccac tgttcgttcc aatttcttga tttgctgcgt cagtgccggc tgggtaatcc
     9781 ccaacaactg ggctgactgg gtgtagttca tggtttctgc taattgcaaa aaatacgtga
     9841 gagttttgga ggaaaaaatg cgctcttgtt tcgtcttcat agggcggctt ccctttcgtt
     9901 tataatttga taacgttact caaccatcat cataagtggc atttaaaaaa acgcaacgga
     9961 tttgctgcgt ttttaatcgt tacgttaagt ttcaactaaa tcactgcttg ttagctggct
    10021 gtggtcgcca actttgccat ccagtatagt cctcaacgtg tagcaagttc tctgcattct
    10081 tgacccgatc agctgaaggc ggctcgatac cttccagcgg atacgtaata cctagttcat
    10141 ggtacttctt aacccctaac gtatggtacg gaagaatttc cactttctgg accacgcgtt
    10201 tatccaaagt ggcaatataa tctcccaagc gtttgagata aggatcaaag tcggttcgtt
    10261 ctggcacaag tacgtggcga atccacatat catcgccatg atccgacata tactgaacca
    10321 tatccaaaat gttttcgttt gggaaaccgg ttagcttttt gtgttccgcg gaatcaatgt
    10381 gcttgatgtc aaccaacgaa atatccgtga cggccatcag tttctcaaat tgaccaaacc
    10441 acggctgatc acgggtgaat ggaccacccg aagtatccaa acaagttgag atacccagtt
    10501 ccttagcttt ggtaaaaagt tccaggataa aatcaatttg gacgagactt tcgccaccgc
    10561 tacaagtaat ccccccttgt tcgccccaga aggctttata tcgctgtgca tctgccagga
    10621 tctgatcagc ggtcatttcc tcgcccacac cgatattcca agtgtcaggg ttgtgacagt
    10681 actggcaccg catcctgcat ccttgcataa agacgacaaa ccgaatcccg ggaccatcaa
    10741 ccgaaccaaa gctttcgact gaatgaacgt atccttttat tgggccttca tgatcctgtc
    10801 ccacttgttc caaaatattt aacgggcttt gtgattgatc gatgagtttc atctatgccg
    10861 cctccagtgc aaataaatac ctaattttca acgattttca tttcagtttg tcaaaaaacg
    10921 gcaacagcat cgttgccgtc ttttgacaaa acaggaatga tctcctgttt tgcgaataga
    10981 ttgacttgat tacatttcgt cgaagaaggt ccgagcgata acatcgtctt gctgttcttt
    11041 ggtcaggtct gcaaagtaga cgcagtaacc ggaaactcga acagtcaagg ttggatattc
    11101 ttctgggtgc ttctgggcat caatcaacgt ttctttattg aagacgttga tgttaaggtg
    11161 catgccgcta ttttccatgt agccgtcaac catgtgaacc aaggtgtcct tacgggtttc
    11221 atcgtcatgg cctaaggtgt tcggtgttac cccaaaggta ttgctgatcc cgtctgttgc
    11281 atagtgatat gggatcttgg cggttgacat caaggaagcc aaagcaccgt tcttttcagc
    11341 accatacgcc gggttggcac caggtgagaa tggttcgccc ttctgacggc cgtttggtgt
    11401 tgtcccggta ttcttaccat aaaccacatt agatgtaatg gtcagaacac tggtactgag
    11461 cttagcaccg cgatacagat gatgtgtatt catcttgttg tagaaggtct taaccaacca
    11521 cttagcaatg ttgtctgccc ggtcatcatt gttaccataa cgcggatagt catcattgtc
    11581 agcaacaaag tcgattgcaa cgccattttc atcccgaatt gccttcacgt ggccatactt
    11641 gatggcactg atggaatcaa ccgcatgtga caaaccggaa atcccggtag caaacgtccg
    11701 attcagacgt gtatccttca atgccaactg cgcagcttca tagtagtact tgtcatgcat
    11761 gtagtgaata acattcagtg cattgacata gacatctgct aaccagtcca tcatcttgtc
    11821 gaacttcttc atgaactcgt catagtcgat atagtcgctg gtgatcggct cgtattcagg
    11881 tcccacctgt gcttcctgaa tttcgtcttt accaccgttg atcgcataca gcacggtctt
    11941 ggctaggttt gctcgcgccc cgaagtactg aacaccatct gcaattggct gcgcggaaac
    12001 acagcaagca atgccgtaat agtcggttcc ccattcgtta cgcatcagat catcgttttc
    12061 gtattgaatg gttgaacttt ggatggacac ttcagtggca taacgtttga acccttcagg
    12121 aagacgttcg ctccacaaca aggtgatgtt tggttccggt gccgcgccca tgttgtccaa
    12181 ggtcttcagg aagcggaacg cggtcttggt aacatgatga cggccatcat tacccatccc
    12241 tgccaaggac agtgttgccc agatcggatc gccggagaac agtgagttgt attcttcagt
    12301 ccgaatgaaa cgtaccatcc gtaacttcat aaccaaatga tcgatgagtt cttgtgcctg
    12361 ctcttcattc agcttgccca aacgcatatc ccgttgaata taggcatcaa tcactgtatc
    12421 gatacggccg acagacattg ccgcaccatt ttgggtctta acggctgcca ggtaaccgaa
    12481 gtagatccac tgaacagctt cttgagcatt agcagctggg cgggaaatgt catagccgta
    12541 ttctttggcc atcttcttca tgtcattcaa ggcacgatac tgttcgttaa tttcttcgcg
    12601 cagtttgata acatcatctg tcatctcgcc atcgccggtc aggttgtaat cgttgaactt
    12661 ctcagccatc agccggtcaa tcccataaat agcaattcga gggaagtccg aaacgatccg
    12721 accacgacca taagcatccg gtaagccggt cacaatctta tagtggcggg ctttgcgcat
    12781 ttccggcgta taagcatcaa aaacaccttg gttatgcgtc ttacgatatt cggtaaagat
    12841 cttgtgctca ttagcgtcgg tttcgaagcc ataggatttc aaagcatcct cagccatccg
    12901 gataccgcca aatggcatga atgcccgctt aaacggctta tcggtttgga caccgacaat
    12961 cttttcgagg tccttattca gataacctgg gccatgagaa gtaatggtcg atggaatatt
    13021 gttatctgca tccagcacgc cgccattggc acgttcttgc tttttcagat tcaaaacctg
    13081 attatttaaa acggtcgttg cttcagtggg gccagcaagg aaactctcgt ccccatcata
    13141 ttggttcagg ttatgctcga taaaatcgcg cacgttaatt tcttcttgcc agtcgccgcc
    13201 gttaaaagcc ttcccaataa cttaggaact tttggttcgt caagctgttt cataggtatt
    13261 gcctcctaaa agtgaattac agatgtgaca gttcttacaa actcagtata acacgaaggc
//
