LOCUS       c00050_gnlPro..        13307 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JIBHCKEE_50.
ACCESSION   c00050_gnlPro..
VERSION     c00050_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 04:31:47
            Original ID  :: gnl|Prokka|JIBHCKEE_50
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13307
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13307
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9846:13097]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9847..13097
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13307
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13307
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(2..1030)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 98; E-value: 1.8e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg50_1"
                     /sec_met_domain="MFS_1 (E-value: 2.9e-31, bitscore: 98.0,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRQAKIGWQGQTAAFLLSQNLFVFGTSTVFFAVLWDIALKTSSGA
                     WMTYVSLATALPAILISLSAGVLADRYNRKWLIVISAVGVTVLTLAVAYVFAFVTQELW
                     LLLVIAVIRSLGNGLENPAANALLPQLVPEKQLTRVNGYNQMLMAAMLVISPLLAGYIL
                     SDLGIFWIFVIDALTAVLAVLCLGIVHVPTPVTNPDQTTKQQNGIVAGLRYVGHTPVLL
                     AFMLFTGLAFILIAPSSQLSTLYVNRTFGSEVWHLTFNEWSWTIGAGLGGLFIARQKKF
                     RDQLGLIALGFAGSGIAFAEMGLKQPFITYLLFMFVSGIFYPLIQAGQTIYLQENVPAD
                     KLG"
     CDS             1128..1823
                     /locus_tag="ctg50_2"
                     /transl_table=11
                     /translation="MPQKIFIVEDDDVIAKTIGNYLNRWAFTVELVQKFDQVDAEIRAA
                     APDLVIMDISLPYFNGFHWLSELRKHSKVPVIFLTSSGDDMNLVMAMNLGADDFLAKPI
                     ELPVLLAKIQGMLRRTYQYQQTDTNLNHGEFTLVPTDNQLRSPTQVIDLTPKETKLLSL
                     LFGADGEVVTREAMIEKLWEGDEFIDRNALAVNMNRLRKKVAPVGLNQLIETVKGKGYR
                     LANKEGGHD"
     CDS             1816..2775
                     /locus_tag="ctg50_3"
                     /transl_table=11
                     /translation="MIKAFLRARWMVWLSLLILLVASLLANWLINASLEVALNSWFFAL
                     IPLLVIGGCDFWRFRREWSQLQGDVTLLAADQISDPLGQVYFQKIQMLQQALRQNHDTY
                     RDQEQETVDTLQLWTHQIKTPLTALDLLLQVEPVNASDARLEVGKINRYLTVMLNYLKL
                     TTLNTDLVLTELPLKPLVNETVRDLAKLFIAKDLTVTVETLPTVVSDSQWLRFIFEQLL
                     TNAIKYTPHGSIRIYAKGDAVLVADTGIGILPEDLPRIFEQGYSGYKGRANQKASGLGL
                     FLSRQIAQKLGLHLTVSSKVGVGSTFAIHFPQTRWLAE"
     CDS             2869..3639
                     /locus_tag="ctg50_4"
                     /transl_table=11
                     /translation="MSTLLKLKNVEKTYTSRGAQPVQALVNISFSVESGEFVAIMGESG
                     SGKSTLLNLIATLDDPTGGEISLKGQDLRKVKEGARAKFRREHLGFIFQDFDLLDTFNV
                     QDNIFLPLVLAKKPLEIMKNRLTQLAPRLGITDLLKKYPYELSGGQQQRVAAARAMITE
                     PEILLADEPTGALDSRTSSELLDLLTDVNAESKQTILMVTHSAVAASHSQRVLFIRDGQ
                     IFHQLYRGELQQPEFLTRISETMTAMLTKEGEAQ"
     CDS             3636..5621
                     /locus_tag="ctg50_5"
                     /transl_table=11
                     /translation="MKFYFKLAATNLKADRRLFVPFVITTSFLMAINLIMLNAYTSSDV
                     LFRQFGQAAGKSLFSFGSMTTAIISVILIIYANNFLRKQRIRQLGLYNIIGFGKRELSK
                     MMATEKLLLLLTTLLCGGILGTVLSRLSYLTLAKMLHVNHNLDFGLSQTAFSIAGLITI
                     GLFIVLMLVDEFWLLRKHPIELVREQNAGEREPKTKWLTLIVSIASLAAGYTIAVTVKN
                     PLQAMSLFFFAVVLVIVGTYGLFTSGSVFVLKWLRHRKNYYYKPKHFINVSNLLYRMQQ
                     NGAGLASIAILVTMTLITLATTATLFFGIHEIVNSQTPVDLAYSINPKRPDAANQLRTL
                     AKTHHVKIHSMRTFTGPSSTLALLEKNKLDSQANFNGPFSFNNARSVQLMTVENYNRYT
                     GKHVALNHDEVLIYASNHYQPATLRIGKQTYHVAKQVTSFPNAPKTFIPNLFVALPSDA
                     QLLTALHALYPKRSMALLKADVTTNQDVTLSGSHANQVKLYHAVVKSGIALPESVQSRA
                     ANYDDTASMMSSFLFLGVVFGVTFILATLLILYYKQLAEGYADARRYTILQRVGLSLRE
                     VRATINSQLLTLFYLPLIVAAIHVGFALPFVQRIMMLFGLPDWQFFLTVSLITLAIFAV
                     IYVLMYRLTGNVYYRIVSRRQPSSRG"
     CDS             complement(5797..6909)
                     /locus_tag="ctg50_6"
                     /transl_table=11
                     /translation="LSTQNYPKLIQAMLPSLPDYIQDYYHSQKAIPIADSTLYQYLHFY
                     QEFLHWLISSRVTDAVSPQNVPLKTLERLSLRDAQAFVAYLLERPSKTHPNKRMTRRSV
                     ALRLVGIKALYRFLTEESEPNADGEPYFYRNVWNKVKLKTHAETTTYRNHKLQEMLFVD
                     GEDARFLQWLDRQYAQQLPSKPRAYFEATKERNLAIIALLFGSGVRVSELVNMNLEDLN
                     MDRHTVQVVRKGNFQDRVNFADWIDPYLTAYLKSQTAMIGHQKPTSPLFVTQIGQTVNR
                     IRQNTIEAFFKRYTTAYGRPSTPHKARHTLGTNIYTVTKDVQQVADQLGQTTTSATDLY
                     INLSDKSGKAALREVSETAAKAVDQHPQQP"
     CDS             complement(7795..8727)
                     /locus_tag="ctg50_7"
                     /transl_table=11
                     /translation="MTTLIFGHQNPDTDAITSAMSWAEFQKQAGNTDVEAVALGEPNDE
                     TKFVLDHFKVAAPRVIKTAANETGHVMLVDHNEFQQSVADIEDVQIDSVVDHHRIANFH
                     TASPLYYRAEPVGSTNTVIFELFQEHGYEISPTLAGLMASGLISDTLLLKSPTATDKDK
                     KILPEMAKIAGIDLQSYGLAMLKAGTNLAAKSDMDIIEGDAKSFTMGGKSIRIGQVNTV
                     DLDDIYARQDELVAAMTKEAQAKGYDDFLLIATDILNSNSTGFAVGADRDKVAAAFNEK
                     FDANDRLALPGVVSRKKQVVPPMQGAFEG"
     CDS             complement(8757..9725)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     55.5; E-value: 1.4e-17)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg50_8"
                     /sec_met_domain="LysR_substrate (E-value: 1.8e-27,
                     bitscore: 85.5, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.2e-18, bitscore: 55.5,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKQERIFSSKTLTYFLQLAETMNYTQSAQLLGITQPALTQQIK
                     KLERTVGAPLFYSVGKKLHLSDAGRTMLKATHEIYEILNQTTDEIQQSTSATVGKINIG
                     LLSSIEDSAFNAFIAHYYDLNPEVEITLRMMTRHEIWEALENNQIDLAIMNLPDETIKN
                     WKPYASKKILDEQLLFLHHDNSLANRKRLHFKDTLAEPWVTYPDDYFLGQLLHEAYKNQ
                     MVDFPHVVAHFTTPYQLTQFVNHTGVNTALPTSFVAAHADQIKAHAVAFEPAIRFETSF
                     VYRKEKADIPRIANFFKTFDAHLSEKDYLSRVSENSGKIER"
     CDS             complement(9847..10698)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 66.6;
                     E-value: 9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_9"
                     /sec_met_domain="Radical_SAM (E-value: 4.7e-27, bitscore:
                     84.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLIDQSQSPLNILEQVGQDHEGPIKGYVHSVESFGSVDGPGIRF
                     VVFMQGCRMRCQYCHNPDTWNIGVGEEMTADQILADAQRYKAFWGEQGGITCSGGESLV
                     QIDFILELFTKAKELGISTCLDTSGGPFTRDQPWFGQFEKLMAVTDISLVDIKHIDSAE
                     HKKLTGFPNENILDMVQYMSDHGDDMWIRHVLVPERTDFDPYLKRLGDYIATLDKRVVQ
                     KVEILPYHTLGVKKYHELGITYPLEGIEPPSADRVKNAENLLHVEDYTGWQSWRPQPAN
                     KQ"
     CDS             complement(10836..13097)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_10"
                     /sec_met_domain="Gly_radical (E-value: 4e-42, bitscore:
                     132.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.5e-245, bitscore:
                     804.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLDETKVPNYWEGFNGGDWQEEINVRDFIEHNLNQYDGDESFL
                     AGPTEATTVLNNQVLNLKKQERANGGVLDADNNIPSTITSHGPGYLNKDLEKIVGVQTD
                     KPFKRAFMPFGGIRMAEDALKSYGFETDANEHKIFTEYRKTHNQGVFDAYTPEMRKARH
                     YKIVTGLPDAYGRGRIVSDFPRIAIYGIDRLMAEKFNDYNLTGDGEMTDDVIKLREEIN
                     EQYRALNDMKKMAKEYGYDISRPAANAQEAVQWIYFGYLAAVKTQNGAAMSVGRIDTVI
                     DAYIQRDMRLGKLNEEQAQELIDHLVMKLRMVRFIRTEEYNSLFSGDPIWATLSLAGMG
                     NDGRHHVTKTAFRFLKTLDNMGAAPEPNITLLWSERLPEGFKRYATEVSIQSSTIQYEN
                     DDLMRNEWGTDYYGIACCVSAQPIADGVQYFGARANLAKTVLYAINGGKDEIQEAQVGP
                     EYEPITSDYIDYDEFMKKFDKMMDWLADVYVNALNVIHYMHDKYYYEAAQLALKDTRLN
                     RTFATGISGLSHAVDSISAIKYGHVKAIRDENGVAIDFVADNDDYPRYGNNDDRADNIA
                     KWLVKTFYNKMNTHHLYRGAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPA
                     YGAEKNGALASLMSTAKIPYHYATDGISNTFGVTPNTLGHDDETRKDTLVHMVDGYMEN
                     SGMHLNINVFNKETLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVIARTFFDEM
                     "
ORIGIN
        1 gtccgagttt atccgcaggc acattttcct gcaagtagat agtttgcccg gcctgaatca
       61 gcggataaaa gattcctgag acaaacataa atagcaaata agttataaac ggctgtttca
      121 aacccatttc ggcaaatgca attccgctgc ccgcaaagcc aagcgcaatc aaaccaagct
      181 gatcccgaaa ctttttttgc cgtgcaatga acaaaccgcc taacccggca ccaattgtcc
      241 atgaccactc gttaaacgtc agatgccaga cctccgaacc gaatgtgcga ttgacgtata
      301 atgtcgataa ttgggaagaa ggggcaatta aaataaacgc cagtccggtg aagagcataa
      361 atgccagcaa taccggcgtg tgacccacgt agcgcaatcc ggcaacaatg ccattttgct
      421 gcttggttgt ttgatccgga ttggtgaccg gtgttggcac gtgaacaatc cctaagcaca
      481 acactgccag taccgctgtg agcgcatcga tgacaaagat ccaaaaaatc cccagatcgc
      541 tcaaaatata cccggccagc agcggggaaa tcacgagcat agccgccatc aacatttgat
      601 tatatccatt cacccgcgtc agttgctttt ccggtaccaa ctgcggcaat aacgcgttag
      661 ccgccggatt ctccagacca ttccccaaac tgcgaatcac cgcgatgacc agtaacaacc
      721 atagctcctg cgtcacaaac gcaaacacat aagctactgc gagggtcaaa acggtgacgc
      781 cgactgcaga aatcacaatc agccatttac gattgtagcg atccgccaag acgcctgctg
      841 aaagcgaaat taaaatagct ggcagggcgg ttgctaacga aacataggtc atccacgcgc
      901 cggaagaggt ttttagcgca atatcccaga gcaccgcaaa aaagacggtg gacgttccaa
      961 aaacaaataa attttgactt aagagaaagg cggcagtttg cccctgccac ccaattttgg
     1021 cttgtctcac ttttaacacc tgaaatcagt taaaatagaa gctgacttta gtttaaagca
     1081 attgacttaa aaagcccacg aatcaccacg aggggagcat aacaaacatg ccgcaaaaga
     1141 tttttattgt tgaagacgac gatgtgattg caaagacaat tggtaactac cttaatcggt
     1201 gggcatttac ggttgaattg gtccaaaaat tcgatcaggt ggacgctgaa attcgcgccg
     1261 ccgcaccgga tctggtgatt atggatatta gcctaccgta ttttaatggc ttccactggc
     1321 tgagcgaatt gcgcaaacat agcaaggtcc cggttatctt cctgaccagt tccggggatg
     1381 atatgaatct ggtgatggcg atgaatctcg gtgcggacga ctttttagct aagccgatcg
     1441 agctaccggt tttattggcg aagattcagg ggatgttgcg gcgaacctac caataccagc
     1501 aaaccgatac caatttaaat cacggtgagt ttacgctggt cccgaccgac aaccaactac
     1561 gctcgccgac tcaagtgatt gacctcaccc cgaaagagac caagttatta agcctgttat
     1621 ttggtgccga tggtgaagtg gtcacccgag aagcgatgat cgagaagtta tgggaaggcg
     1681 atgagttcat tgaccgcaac gccttggcag tgaacatgaa tcggttacgc aaaaaagtcg
     1741 ccccggtagg actcaaccaa ctgatcgaaa ccgtcaaagg aaaaggctac cgtttggcga
     1801 ataaggaggg cggccatgat taaagctttt ttgcgcgccc gctggatggt ttggctgagt
     1861 ttactcatct tactggttgc cagtctgtta gcaaactggc tgattaacgc ctcgcttgaa
     1921 gtcgcgttaa acagctggtt ttttgcactg attccgttac ttgtgatcgg cggctgcgat
     1981 ttttggcgat ttcgccgtga atggtcacag ctccaaggcg atgtcacact gcttgcggct
     2041 gatcaaattt ccgatccgct tgggcaggtt tattttcaaa aaatccaaat gctgcaacag
     2101 gccttgcgtc aaaatcatga cacgtatcgt gatcaggaac aagaaacggt cgataccttg
     2161 caactgtgga cccatcaaat taaaacaccg ctgactgcac tggatctctt attacaggtt
     2221 gaacctgtca atgccagcga tgcgcggctt gaagttggta aaatcaaccg ttatctgacc
     2281 gtgatgctga attacctcaa actgaccaca ctgaataccg atttggtgtt aaccgaatta
     2341 ccactaaaac cgcttgttaa cgaaaccgtg cgggatttag cgaaattgtt tattgccaaa
     2401 gacttaacgg tcacggtaga aactttgcca actgtggtga gtgatagtca gtggctgcga
     2461 tttattttcg agcaattact aaccaatgcc atcaaatata ccccgcatgg gagcatccgg
     2521 atttatgcca agggcgatgc cgtgctggtg gctgacaccg gtatcggcat cctgccagaa
     2581 gatctaccgc ggatttttga acaaggctat tccggataca aaggtcgcgc caatcaaaag
     2641 gcaagtggct taggtctgtt tttaagccgg caaattgccc aaaagctagg gttacacctg
     2701 accgtttcat caaaagtcgg tgtcggcagc acctttgcca ttcacttccc gcaaacgcgc
     2761 tggctagccg agtaagccac cttaccagct tgtaagcaac gcacgctgac tgtaagtagt
     2821 ttttcggcaa tatccctttt aagctgataa atgaaagggg cggatcttat gtcaacatta
     2881 ttaaagttaa aaaatgtcga aaagacttat accagtcgcg gtgcccaacc ggtacaggca
     2941 ctcgtgaaca tcagtttttc cgttgaatca ggagaatttg tcgcgattat gggggaatcc
     3001 ggttcaggca aaagtacctt actgaactta atcgccacgc ttgatgatcc taccggtggc
     3061 gaaatcagcc ttaaaggaca ggacctgcgc aaagtcaaag aaggcgcacg ggctaaattt
     3121 cggcgggaac atctcgggtt tatttttcag gattttgact tgcttgacac ctttaacgtt
     3181 caggacaaca ttttcctgcc attagtttta gccaagaagc cgcttgaaat catgaaaaat
     3241 cggctcaccc aactggcgcc gcgtctaggt atcaccgatt tactgaaaaa atacccatat
     3301 gaactttccg gtggccaaca acaacgtgta gccgctgctc gggcaatgat caccgagccg
     3361 gaaatcctat tggcagacga acccaccggc gcacttgatt ctagaacctc cagtgagctg
     3421 ttggacctgc taaccgatgt caatgccgaa agtaagcaga caatcctcat ggtgacgcac
     3481 agtgcggttg cggccagtca tagccagcgt gttttgttta ttcgcgatgg tcagattttc
     3541 catcagctgt atcgcggtga attacagcag cccgaatttt tgacccgaat cagcgaaacc
     3601 atgaccgcaa tgctgacgaa ggaaggcgag gcgcaatgaa attctatttc aaattagccg
     3661 ccaccaacct taaagccgat cgccgtttat ttgtgccatt tgtcatcacc actagctttt
     3721 tgatggccat taatttgatc atgctaaacg cctacacgag cagtgatgtt ttgttccgcc
     3781 agttcgggca ggcagctggc aaatcactgt tttcatttgg ctcgatgacg accgcaatca
     3841 tttccgtcat cttaatcatc tacgccaaca actttttgcg taaacagcgt atccgccagt
     3901 tggggctcta caacatcatc ggctttggca aacgtgaatt aagcaaaatg atggctacgg
     3961 aaaagctgct gctgttgctg acaaccttat tgtgcggcgg gattttggga accgtgctgt
     4021 cacgccttag ctatctcact ttggccaaaa tgctgcatgt caatcacaat ctcgattttg
     4081 gcttgagtca aaccgccttt agcattgccg ggttgatcac gattggcttg ttcattgttt
     4141 taatgttggt tgacgagttc tggctattgc gtaaacatcc catcgaactc gtacgcgaac
     4201 aaaacgccgg ggaacgggaa cctaaaacca agtggctaac tttgattgtc agcattgcga
     4261 gtctggctgc cggttatacg attgcggtca ccgtcaagaa tccgcttcaa gcgatgagtt
     4321 tgtttttctt tgcggtcgtc cttgtcatag tcgggactta cggtctcttc acgtccggct
     4381 cggtattcgt tttaaaatgg ctgcgtcacc gcaagaacta ctattacaaa cctaaacatt
     4441 ttatcaacgt atcaaatctg ctttaccgga tgcagcaaaa cggcgcggga ttggcttcga
     4501 ttgctatttt agtcaccatg acgctgatta cgcttgcaac cacggcaacg ctattctttg
     4561 gcattcatga gattgtcaac tcgcaaactc cggttgattt agcttactca atcaacccca
     4621 agcggccgga tgcagcgaac caactacgaa ccctggctaa aacacatcac gtcaaaatcc
     4681 actcgatgcg aacctttacc ggaccctcaa gtacgcttgc tttattagaa aaaaacaagt
     4741 tagattctca agctaacttt aacggcccgt ttagcttcaa taatgcccgt tcggttcagc
     4801 tgatgaccgt cgaaaattat aatcgctata ctggcaaaca tgtggctctt aatcatgatg
     4861 aggttttaat ctatgcctcc aatcattacc aacccgcgac gttgcgtatt ggcaaacaga
     4921 cttaccacgt cgccaaacaa gtcaccagtt ttccaaatgc gcctaaaacg tttattccta
     4981 acttgtttgt cgcgcttcca tctgacgcac aactattaac cgctttacac gcgctttatc
     5041 caaaaaggtc aatggcactg ctcaaagccg acgtgaccac taatcaagac gtaacattaa
     5101 gcggcagtca cgccaatcag gtcaaacttt atcatgcagt cgtcaaaagt gggattgcat
     5161 taccggaatc ggttcagtcg cgagccgcta attacgatga tactgccagc atgatgagca
     5221 gtttcctatt ccttggggtt gtctttgggg tgaccttcat cctggcaacc ttgctgattc
     5281 tttactacaa gcagttggca gaaggctacg cggatgcacg ccgctatacc atcttacaac
     5341 gcgtcggcct gagccttcga gaagttcgcg ctaccattaa cagtcagcta ctcacactgt
     5401 tttacctgcc tttgatcgtc gctgccatcc acgtgggctt tgcattgccc tttgtccaac
     5461 gtattatgat gctattcggc ctgccggatt ggcaattctt cttaaccgtt tcgttaatca
     5521 cgcttgcaat ttttgcggtc atctacgtgc tgatgtaccg cttgactggc aacgtttatt
     5581 atcgaattgt ttcccgccgt cagccatcca gccgtgggtg agggcggcct gatgcagagc
     5641 ataaaaaagc tgcctgatcg caagtcatca aaggcgatca ggtagctttt ttctatgtca
     5701 accagcatca aaaaatgtcg ccactgttat ctcactgaat actgtaacgt taattagcgc
     5761 cgcaacatga cttaaccaga caactaaccg ccgacattat ggttgctggg gatgttgatc
     5821 cacggctttg gcggcagttt ccgaaacttc gcgtaaggcc gcttttccac ttttatcgct
     5881 gagattgatg tacagatccg tagcgctggt cgtcgtttgt ccgagttgat cggcaacttg
     5941 ctgcacatcc ttggtgacgg tataaatatt ggttcccaag gtatggcgtg ctttatgggg
     6001 tgttgatggg cggccataag cggttgtata gcgtttgaag aatgcttcaa tcgtattttg
     6061 gcgaatgcgg ttcaccgttt ggccgatttg cgtcacaaat agcggagaag taggcttctg
     6121 gtgcccaatc atcgcggttt gggacttcaa ataagccgtt aaataaggat caatccagtc
     6181 agcaaagtta acgcgatcct gaaaattacc tttacgcacc acctgcacag tatgacgatc
     6241 catattgaga tcttccaaat tcatattgac caattcacta acccgcacgc cggagccaaa
     6301 cagcagcgca ataatcgcca aatttcgttc cttcgtcgcc tcaaaataag cgcgcggttt
     6361 cgatggcagc tgctgagcat attgccgatc cagccactgt aaaaagcgcg catcttcgcc
     6421 atctacaaac aacatttcct gcagtttatg attacggtaa gtcgtcgtct ccgcatgggt
     6481 cttaagtttc accttattcc aaacattgcg gtaaaaataa ggctcaccgt ctgcatttgg
     6541 ttcgctttct tcggttaaga accgataaag ggccttgatc ccgaccagtc gtaacgcaac
     6601 actgcgccgc gtcatgcgtt tattcggatg ggttttcgac ggccgctcaa gtaaatacgc
     6661 cacaaacgcc tgcgcatcac gcaaggaaag ccgctctaag gtcttcaaag gcacattctg
     6721 tggcgaaacg gcatccgtga cccgactgga aataagccaa tgcagaaatt cctggtaaaa
     6781 gtgcaggtac tggtaaaggg tagaatccgc gatgggaatt gctttttggc tgtgatagta
     6841 atcctgaata tagtccggca gggaaggtag catggcttgt attaatttag ggtagttctg
     6901 tgtcgacaaa taaagtcacc tcgaacatat gttttctttt ggataatttc agtatacgcg
     6961 aaaaaaccag tgcgtggcga gggataatga cgaaaatatc ggtaattcgc aacgatatgc
     7021 gccgaaaaaa gcaccagtgt agaactgaat aaagttttag tattatccaa aggtaaatgg
     7081 gcttctaatc atcaagccag ctaaatcacc aaatttgttg atctgtcatt tgacactaaa
     7141 cttagttgca tttcaaattt gaattcactg cacgatcagg acatctgtgc tgatgtcctg
     7201 attccacggc gccgctttag caacagttta accaattaac caacgattca ttggctgcaa
     7261 tcaaatcaat tttcgtattt tgatccagaa ttcagctgac agcaacactt gcgacttgaa
     7321 tgctgtttat gactcaaaat gatactttct acaaatctgc tttgattaat gctgaattta
     7381 catatattta gcaacgactg gtcattttca aaccagaaaa aaacaaataa agcgcaccgc
     7441 tcacatccgt acaattgatt tgcttctctc aaaagttttt gagctgtctg tcaggtgagg
     7501 ggacttgcat caatcgtttt gccatttgaa caccaaataa gtcacgtcaa agtcaacgac
     7561 tcaaaatctc cattctagtt tacataatat atattatacg aagtagttat aaggctgcgt
     7621 tttttgcacc tcgttttaaa tttgaactat tcttactgaa aaatttcgca ataatcacat
     7681 ttctgcacct tcagatctaa aaattcgact tttttgttct tccaagtttt tgagcacaaa
     7741 aaaatcgcaa ccacaaacgg ctgcgattta taaaaccaat tattaagttc aaaattaacc
     7801 ttcaaacgca ccttgcattg gcggtacgac ctgcttctta cgtgaaacca cgccaggcag
     7861 tgccaaccgg tcattggcat caaacttttc gttgaatgct gcggccactt tgtcacgatc
     7921 tgcgccaaca gcaaagcccg ttgaattgct gttcagaata tcggttgcaa ttaacaggaa
     7981 gtcatcatag cccttcgcct gtgcttcttt ggtcatagcg gccaccaatt catcctgacg
     8041 cgcataaata tcatcaagat caactgtatt cacttgtcca atacggatag acttaccgcc
     8101 catcgtaaag ctcttcgcat cgccttcaat gatatccata tccgacttgg cagctagatt
     8161 ggtgcccgcc ttcaacatag ccaaaccgta tgattgcagg tcaatgccag cgattttagc
     8221 catttccggc aagatctttt tgtccttgtc ggttgcagtc ggtgacttca gaagcagggt
     8281 atccgaaatc aagccagaag ccattaagcc tgccagtgtt ggtgaaattt catagccgtg
     8341 ttcctggaac aactcgaaaa tcaccgtgtt ggtactgccc actggttctg cccggtaata
     8401 tagtggtgac gccgtatgga agttggcaat gcggtggtga tcaaccactg aatcgatttg
     8461 cacgtcttcg atatcagcaa cgctttgctg gaattcgtta tgatcaacca acattacgtg
     8521 cccggtttca tttgcggctg tcttaatgac ccgcggcgca gcaaccttaa aatgatccaa
     8581 tacaaacttg gtttcatcgt ttggttcacc gagtgctact gcttcaacat cggtattacc
     8641 tgcttgcttc tgaaattcag cccaactcat ggcgcttgta atcgcgtctg tatcagggtt
     8701 ttgatgtcca aaaatcaaag tcgtcatgtt atctgatcgc tcctcagctg aatagtttac
     8761 ctttcaattt taccactgtt ttcgctgacc cgcgatagat aatctttctc agataaatgt
     8821 gcgtcaaacg tcttaaagaa gttggcaatc cgcggaatat cagctttttc cttgcgatac
     8881 acaaacgagg tctcaaagcg aatcgctggt tcaaaggcaa cggcatgcgc cttgatttga
     8941 tcagcatgag cggcaacaaa actggttggt aacgcggtgt taacaccggt atggttgaca
     9001 aactgagtta actgatatgg cgtggtaaaa tgcgccacaa catgcggaaa atcaaccatc
     9061 tgattcttat atgcctcatg caacaactga cccaggaaat agtcgtctgg ataagttacc
     9121 cacggctcag ccagcgtatc tttgaaatgc aggcgtttgc gattagccag ggaattatca
     9181 tggtgcagga acaataactg ttcatcaaga atcttcttgc tggcatacgg tttccagttc
     9241 ttaatcgtct catcaggcag attcatgatg gccaaatcaa tctggttgtt ctccaatgct
     9301 tcccagatct catgacgtgt catcattcgc aacgtgattt ctacttcagg attaagatca
     9361 tagtagtgcg cgataaaagc attaaacgca ctgtcttcaa ttgaacttaa caagccaata
     9421 ttaatcttac cgactgtggc actggtactt tgctgaatct cgtcagtcgt ctggttcaaa
     9481 atttcataaa tctcgtgtgt cgccttcaac atcgtgcgac cggcatcgga taaatgcaac
     9541 ttcttaccaa cggaataaaa caatggtgcc cccactgttc gttccaattt cttgatttgc
     9601 tgcgtcagtg ccggctgggt aatccccaac aactgggctg actgggtgta gttcatggtt
     9661 tctgctaatt gcaaaaaata cgtgagagtt ttggaggaaa aaatgcgctc ttgtttcgtc
     9721 ttcatagggc ggcttccctt tcgtttataa tttgataacg ttactcaacc atcatcataa
     9781 gtggcattta aaaaaaacgc aacggatttg ctgcgttttt aatcgttacg ttaagtttca
     9841 actaaatcac tgcttgttag ctggctgtgg tcgccaactt tgccatccag tatagtcctc
     9901 aacgtgtagc aagttctctg cattcttgac ccgatcagct gaaggcggct cgataccttc
     9961 cagcggatac gtaataccta gttcatggta cttcttaacc cctaacgtat ggtacggaag
    10021 aatttccact ttctggacca cgcgtttatc caaagtggca atataatctc ccaagcgttt
    10081 gagataagga tcaaagtcgg ttcgttctgg cacaagtacg tggcgaatcc acatatcatc
    10141 gccatgatcc gacatatact gaaccatatc caaaatgttt tcgtttggga aaccggtcag
    10201 ctttttgtgt tccgcggaat caatgtgctt gatatcaacc aacgaaatat ccgtgacggc
    10261 catcagtttc tcaaattgac caaaccacgg ctgatcgcgg gtgaatggac cacccgaagt
    10321 atccaaacaa gttgagatac ccagttcctt agctttggta aaaagttcca ggataaaatc
    10381 aatttggacg agactttcgc caccgctaca agtaatcccc ccttgttcac cccagaaggc
    10441 tttatatcgc tgtgcatctg ccaggatctg atcagcggtc atttcctcgc ccacaccgat
    10501 attccaagtg tcagggttgt gacagtactg gcaccgcatc ctgcatcctt gcataaagac
    10561 gacaaaccga atcccgggac catcaaccga accaaagctt tcgactgaat gaacgtatcc
    10621 ctttattggg ccttcatgat cctgtcccac ttgttccaaa atatttaacg ggctttgtga
    10681 ttgatcgatg agtttcatct atgccgcctc cagtgcaaat aaatacctaa ttttcaacga
    10741 ttttcatttc agtttgtcaa aaaacggcaa cagcatcgtt gccgtttttt gacaaaacag
    10801 gaatgatctc ctgttttgcg aatagattga cttgattaca tttcgtcgaa gaaggtccga
    10861 gcgataacat cgtcttgctg ttctttggtc aggtctgcaa agtagacgca gtaaccggaa
    10921 actcgaacag tcaaagttgg atattcttct gggtgcttct gggcatcaat caacgtttct
    10981 ttattgaaga cgttgatgtt aaggtgcatg ccgctatttt ccatgtagcc gtcaaccatg
    11041 tgaaccaagg tgtccttacg agtttcatcg tcatggccta aggtgttcgg tgttacccca
    11101 aaggtattgc tgatcccgtc tgttgcatag tgatatggga tcttggcggt tgacatcaag
    11161 gaagctaaag caccgttctt ttcagcgcca tacgctgggt tggctccagg tgagaatggt
    11221 tcgcccttct gacggccgtt tggtgttgtc ccggtattct taccataaac cacatttgat
    11281 gtaatggtca gaacactggt actgagctta gcaccgcgat acagatgatg tgtattcatc
    11341 ttgttgtaga aggtcttaac caaccactta gcaatgttgt ctgcccggtc atcattgtta
    11401 ccataacgcg gatagtcatc attgtcagca acaaagtcga ttgcaacgcc attttcatcc
    11461 cgaattgcct tcacgtggcc atacttgatg gcactgatgg aatcaaccgc atgtgacaaa
    11521 ccggaaatcc cggtagcaaa cgtccgattc agacgtgtat ccttcaatgc caactgcgca
    11581 gcttcatagt agtacttgtc gtgcatgtag tgaataacat tcagggcatt gacatagaca
    11641 tctgctaacc agtccatcat cttgtcgaac ttcttcatga actcgtcata gtcaatgtag
    11701 tcgctggtga tcggctcgta ttcaggtccc acctgtgctt cctgaatttc gtccttacca
    11761 ccgttgatcg catacagcac ggtcttggct aggtttgctc gcgccccgaa gtactgaaca
    11821 ccatctgcaa ttggctgtgc ggaaacacag caagcaatgc cgtaatagtc ggttccccat
    11881 tcgttgcgca tcagatcatc gttttcgtac tgaatggttg aactttggat ggacacttca
    11941 gtagcataac gtttgaaccc ttcaggaaga cgttcgctcc acaacaaggt gatgtttggt
    12001 tccggtgccg cgcccatgtt gtccaaggtc ttcaggaagc ggaacgcggt cttggtaaca
    12061 tgatgacggc catcattacc catccctgcc aaggacagtg ttgcccagat cggatcaccg
    12121 gagaacagtg agttgtattc ttcagtccga atgaaacgta ccatccgtaa cttcataacc
    12181 aaatgatcga tgagttcttg tgcctgctct tcattcagct tgcccaaacg catatcccgt
    12241 tgaatatagg catcaatcac tgtatcgata cggccgacag acattgccgc accattttgg
    12301 gtcttaacgg ctgccaggta accgaagtag atccactgaa cagcttcttg agcattagca
    12361 gctgggcggg aaatgtcata gccgtattct ttggccatct tcttcatgtc attcaaggca
    12421 cgatactgtt cattaatttc ttcgcgcagt ttgataacat catctgtcat ctcgccatcg
    12481 ccggtcaggt tgtaatcgtt gaacttctca gccatcagcc ggtcaatccc ataaatagca
    12541 attcgaggga agtccgaaac gatccgacca cgaccataag catccggtaa gccggtcaca
    12601 atcttatagt ggcgggcttt gcgcatttcc ggcgtataag catcaaaaac accttggtta
    12661 tgcgtcttac gatattcggt aaagatcttg tgctcattag cgtcggtttc gaagccatag
    12721 gatttcaaag catcctcagc catccggata ccgccaaatg gcatgaatgc tcgcttaaac
    12781 ggcttatcgg tttggacacc gacaatcttt tcgaggtcct tattcagata accggggcca
    12841 tgagaagtaa tggtcgatgg aatattgtta tctgcatcca gtacaccgcc attggcacgt
    12901 tcttgctttt tcagattcaa aacctgatta tttaaaacag tcgttgcttc agtggggcca
    12961 gcaaggaaac tctcgtcccc atcatattgg ttcaggttat gctcgataaa atcgcgcacg
    13021 ttaatttctt cttgccagtc gccgccgtta aagccttccc aataattagg aactttggtt
    13081 tcgtcaagct gtttcatagg tattgcctcc taaagtgaat tacagatgtg acagttctta
    13141 caaactcagt ataacacgaa ggcaaatcta tgcaagcgtt ttatcgctga tataacaggc
    13201 gttttgctgt tttttcggtg tactttcctg tttcataaaa aaagcttaat cattagcttg
    13261 ataagttgtg cacaaccgta ctgtcatata ataaataaaa aattctc
//
