LOCUS       gnlProkkaOIGACJCJ_41   15751 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIGACJCJ_41.
ACCESSION   gnlProkkaOIGACJCJ_41
VERSION     gnlProkkaOIGACJCJ_41
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 04:05:03
            Original ID  :: gnl|Prokka|OIGACJCJ_41
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 3363
            Orig. end    :: 19114
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15751
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12628]"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12628
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     cand_cluster    1..15751
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15751
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             667..1356
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101:phosphoglycerate mutase (Score: 109.1; E-value:
                     3.6e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_5"
                     /transl_table=11
                     /translation="MTTLYLVRHGQTEFNVQKRVQGMADSALTPKGIADAKALGRGFQL
                     AGVHFDAAFASDLTRAVDTAHFILSGLGEPLPVTRLMGLREENYGKFEGQLANDFSLAT
                     MGIANFHDALANREITLAQTADAAFAANMDQHPNPAETNRMVQERLDRTLRAIAVEAEA
                     KGWERVLVVSHGTAALMWLNYIHYNIDGREMLDNASVTKLMWLNDRFRVTDFNDLSFLH
                     HGQEALG"
     CDS             complement(1353..2042)
                     /locus_tag="ctg41_6"
                     /transl_table=11
                     /translation="MQTTTYPIHERLLIGTLLTAAAGSFDAYTYLLHGEVFAGLQTGNV
                     ILLGVHLGQGQWYTAIRYLVPILAFMFGTMAARALQLHASHRPQPLAEQRWILRYEIIW
                     LLVVSLLGKWLPDLLASAIVSVIAAAQLQEFRRLKGGPFTSLMMTGNLRTAAQSLYDGF
                     IRGQQKGRASAATVGTIILSFALGAGVTGILTHAIGTYALAGATLVLILIDLLLWRDQK
                     TLPQRTA"
     CDS             complement(2330..2593)
                     /locus_tag="ctg41_7"
                     /transl_table=11
                     /translation="MEKEKLHLGDAVVCQVKEDMEAPFTGKIEKVYENSALLTITDYAD
                     QDRQNASELNFKIVANFHAMTKKPWRRNCLGLSTRNRRRPKK"
     CDS             2965..3309
                     /locus_tag="ctg41_8"
                     /transl_table=11
                     /translation="MATSNTTIDQLNEAAQKTALETFAKFYLSRFFGDGLDVFSQLDEQ
                     GDLADINHYLLDNRTLTREELTSGLLTHRSGNLLDLLKQVNVTFNAQGAPETPWAKWYA
                     DQIEGLPQGL"
     CDS             3500..4312
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179:hydrolase (Score: 148.2; E-value: 5.4e-45)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_9"
                     /transl_table=11
                     /translation="MTQYLIVSDIDGTLTANHHDVTEKTTQAIANAVTAGAAFYVATGR
                     MHALAEVVAHQFQPYANIIASNGAVYDFSGERVHHTLGAAALTAVEEVATDLGLNALYF
                     SDDTVYFTGTLPPAIEAAARRFAPSSVAIEVVALPSAAALLTHAATITNGIIFGPSDSQ
                     ALVAGKTALEARNVLHVSASEHTNLELIPKYVDKANAVRELQAKTGIDAAHTIAFGDGL
                     NDLGMLQAAGISVAMGNAVPEVKRVARYVTDTNVDEGVANFLTDFFEK"
     CDS             4418..5425
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     289.3; E-value: 5.1e-88)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_10"
                     /transl_table=11
                     /translation="MMYHAAVDRYETMPVRHAGKTGLMLPVISLGLWQHYGNLDPFGPR
                     RSVILDAFDRGVFHFDVANHYGNGDREPGFGSSERLLGQILATDLKPYRDELVISTKVG
                     YEIHPGPYGVGTSRKAVIQGLNDSLKRLQLDYVDIYYAHRFDDTVALEETVNALDQTVR
                     DGKALYIGISNYDTKQTKEAIAMFKDLHTPFVLNQYSYNMFNRTAETSGLIDALKADGA
                     GLIAYGPLSEGLLSDRYLKGIPDTFKIHPTNQATFAKGKEAVVKQLNALNEIARDRDQT
                     LSQMALAWLLRDPVVTSVIIGTTSVEHLQDNLKATEHLTFTAEEIQQIDDILNA"
     CDS             complement(5534..8062)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 42.2; E-value:
                     1.3e-12)"
                     /gene_kind="transport"
                     /locus_tag="ctg41_11"
                     /transl_table=11
                     /translation="MAIPDHISVRGAYVNNLKHLNVDIPLNKLVAITGRSGSGKSSLAM
                     GVLYAEGMRRYMSALSTYTRRRLGQTSPAAADSVKHIPSAIALRQRPVVPGIRSTVGTA
                     TEALNVIRLMFSRLGSPVCPNGHRVPPTLDIAKAMDLPNDGESGMGMITCPTCGVHFMA
                     FAAEDFAFNSTGACPTCGGTGQARTLAANRLIPDPTLTIRQGAVASWRLPGRNFMPYVA
                     QAIGIDIDTPFQDLPEDQQEQVWHGQRKKYAINIPSKTGKIFHMDHAQYENAFNAVKDS
                     LATTKNERAIERLNRFYEFGVCPTCHGSRFAPKLLAQHLVDQNIAQVSDMTLTQLTAFI
                     PKIYQWLPANMQALAHDIIKELTQLLKPIMDLGLSYLTLSRAAASLSTGELQRIQLSRT
                     LRTETTGVLYVLDEPSIGLHAANVAGLLEVMHGLVDQGNSLVVVDHNTAIINAADQIIE
                     IGPGAGADGGQILDQGSPVEVSHDTNSLIAPFLTGKTPLIVRPQAGSAPIAKAKQLQLT
                     VTNRFNLHHLNVQFPINCFSVVSGFSGAGKSTLIFDALVPALSATKDQPGPTFVRDLKT
                     GGIRHVVAIDATPVGKNVRSTVATYTDILDHLRHLFAGLPAAKAKHYTSSHFSYNVKAG
                     ACPTCGGTGVINLDIQYLPDMQQTCPTCHGRRYNPEVLKIKWHERSIADLLDLDVDSAL
                     TVFKDEPTIAHTLQTLHDMGLGYLHLGESTPTLSGGEAQRLKLVAHMGRSQKDTLFVFD
                     EPSVGLHPLDVQTLVAVFQRLLQTGATVIAIEHDLDVIANADYVLDLGPKGGAEGGHVI
                     AAGTPQAIAKQGHGETAKYLAAHLAAFHVD"
     CDS             complement(8377..8793)
                     /gene_functions="regulatory (smcogs) SMCOG1135:MarR family
                     transcriptional regulator (Score: 59.1; E-value: 6.1e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg41_12"
                     /transl_table=11
                     /translation="MKKQYLSASQSVNQFNRLFSPVSTADIPLNQQNLLFWMATDSTPR
                     TPTNLAKEMHVTKAAITKASGPLLERGLLDKQPDPEDCRSFKLVLSEAGEKAVEDLGPE
                     YLGNLERLYNELGEKKYLKLIKLLSQATGVTVKE"
     CDS             8945..9589
                     /locus_tag="ctg41_13"
                     /transl_table=11
                     /translation="MIDWQILTVYAQKVSSQDHSGHGFDHIERVVANAKQLVAKTAGVD
                     ATVVVAAATMHDTYDDKLVADVGAAKAAAQQAMTAAGLTQAQIQAVTEIIDHMSFKANL
                     SKHQPLSVEGQLVQDADRLDAIGAIGIGRAFMYAGAHGGRMYDPALAPRTTLTASSYRG
                     KDSTVINHFYEKLLKLKDQLNTSAARQLAEHRQQVMLSFLDEFKAEWRSTR"
     CDS             complement(10001..12628)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 57.5;
                     E-value: 2.6e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_14"
                     /sec_met_domain="Pkinase (E-value: 5.8e-16, bitscore: 48.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.8e-09, bitscore:
                     25.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYSLLKLLPITSLKKSGFGFHHDEMWFYCIRDFNFLPAQGWKIH
                     LSVLPNHLGSTIEKVGELASKFDFAFKVPVKWHTALKISYGSYGYLMQGKEVTIYPRSQ
                     EPASLFALCNALDQFLNDASFCDVVTDIQYKDGQIFLRYGSFGKNFRFDDRGNVVPQII
                     NKEGKLIDDIKKIGQYKPEWINTPSFLNKESNESKSKTVYLPADITGIQLVRKRVGSTV
                     FSGRYAGKEVIIKIAMKNRLFDETERSNVSRLLHESKIMQALPESFNHPKLYRTINSDG
                     GSILIEQLIHGVPFNEIISNCTADNSKINLTAVFKKIAYQMRILSKSGIAFRDLSPNNI
                     LIDADQEPYFIDFEIADFAGRIDAFQGGTPGFILPSQIRTRLQRASILSDKFSFASLLF
                     YASTKIVPIFEEEYYNTLNKLYTKMYTLINRLNLTKRNRFLANLAVKIMSNLSFSWTHI
                     IDLLSSDNSIHTPVHGIQARISSGTLRKQILNMSHNYIDQQLHLISATNIYPVHNYSSF
                     NQGPLSLIALMMRYDLAKRSHNYPGDIGNLFNLIYDQWKNEPAHVHNLINGDISLLLIC
                     EYLKNQALTSSSTLAQATSTSERLLFELSEANFDDYSIGMYYGLSGIGITLCLAYMQSS
                     DTKFKQTVLNLLKKVYTNIWSRRYTHSKDVLAIDIGPKKPFPQNESTRDLEYGLAGVGI
                     FFIQYYLITGQLSILASARAIYTSLRKSVQINKVGNLFWYETDATLIHKNGLSKGDLGI
                     LVFLQLFADSTREDKVTQFKDSLANQLLGDSAFLGSPDVNSGISGLILAESIVSANHPL
                     NTQHNRLLLDLSTPYGRTLSWAYNNMYINNSHSFLYGETGIFYSLLVSINSQNTILDNP
                     WKRN"
     CDS             12760..12930
                     /locus_tag="ctg41_15"
                     /transl_table=11
                     /translation="MSEEVAEETLVTRTGLALSELDKLEPGDTDFNHIVFRSVDGGSPC
                     EDVGATELIPY"
     CDS             13065..14672
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 235.2; E-value:
                     2.5e-71)"
                     /gene_kind="transport"
                     /locus_tag="ctg41_16"
                     /transl_table=11
                     /translation="MAVTFRQYLFRLKWRFGVFILMYGLEISALTAVSIFTGNMITALT
                     QFKVNAFVTAAIVMVVATIFQLVMQTLTNIYQVSLQRRLNNDIRTEITKSIAAMPFEQY
                     HARSDAVYTSWMTNDVNTINTQGLRNVGYLIQASWQVVLSIFVLLTYQASLFATTLVCA
                     VLLITVPMIYRKKLSAAAAKWSQENEKLTNRITDILEGFNTLFMANRRHVMVDRVFHAS
                     NAAGHAQVGYIQFNMATQFLINLVNLGSQLFLLIQAGLLAYNRVIPVGAVVTIHSVAGT
                     TFSGLTLMSFALTTVKSVAPIFDKFAKAIPSPQKPKEPVNGLEEGIHLQDVTFTYPHRK
                     EPVLKDVTMTLTAGKKIAIVGPSGHGKTTLLRLISDVLADYQGQITWDAQNYQKLDPRS
                     LRDQITYIDQAPYIFNDTIRFNLTLGQQVADDVLQHAIEAARLTTFMAQQEQGLDTVLE
                     HNGADLSGGQKQRIALARGLIRQSHVIISDEGTAALDPKSGLAIEKLLVALPKTTLIMV
                     THNLRPEIKDQLDQIVTV"
     CDS             15004..15651
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_17"
                     /sec_met_domain="Abi (E-value: 6.1e-21, bitscore: 64.9,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQILRSIIQIFGVIVGFLFYSLAELALVRSELTWGMVGAIAAFII
                     AFGALIAALMVCYRRLYRQQSPLKVAHPVAVVLQGIGLLLLIQVTNSLIMQLTHAPLAA
                     NQSNLIKLVHTYPWGIKLLAVVGGPIVEEYLFRGLLMNSFGSLQKRSWQWVSVLVSAFA
                     FGFAHVAGSRIDYNIFIYAALGAVLAWTYLRTRDMRYSIGLHILNNATILLV"
ORIGIN
        1 ttaatttcaa cggcgccttg attcatgtgc cgcatcagca gtggcaatat gaacaagaag
       61 tcacgattcc gatttcggtt gcgttatcgt tacgccagct caaccaacgc tttaccttta
      121 aagtgatggt ggcagaaggt aagcggctat tggtggctga tcggccttat gccaatattc
      181 cgttcttgcc ggatcgctta caccctgatg ctttattgga tgagcatggg ttgcgtcaag
      241 cgccgatttc ggtcaccatg tttatggaag ctaagacgtt tgagccggtt tcgcaacaag
      301 tggcggcttt gtatccgcat ttggcagcca aaacctgggg cgcttggagt ggcgactata
      361 cggcgttaga agtgactagc cgaaatacga gcaagtcgcg ggcgttggcg tatgtcgctc
      421 agcggtatgg cattgatcag gcacatatca ttgcgtttgg cgatgatatg aatgacttgg
      481 acatgctgca atttgccgga catggcgtgg caatgaaaaa tgcgcgtcca gccattcttg
      541 aagcggcaga cgcgcagaca ccaagcgata acgatcacga tgggatggca gattacttag
      601 cggattattt aaaactggct taatgacgat gacttggaaa taaatgaaaa ttaggggatt
      661 gcgatcatga caacgctata tcttgtccgt catgggcaaa cagaattcaa tgtgcaaaaa
      721 cgggttcaag gaatggctga ctcggcctta acaccaaaag gaatcgcgga tgctaaggcg
      781 ctgggacgcg gctttcaact ggcaggggtg cattttgatg cggcgtttgc gagtgacttg
      841 acgcgggctg tcgatactgc tcattttatt ttaagtggtt tgggtgaacc gctgccggta
      901 acacgactca tgggcttgcg tgaagaaaat tatggcaagt tcgaagggca actggcaaat
      961 gacttttcgc tggcgaccat gggcattgcc aacttccatg atgctttagc caatcgcgaa
     1021 attacgttag cgcaaacagc cgatgcggca tttgcggcta atatggatca gcatccaaac
     1081 ccggcagaga ccaatcgaat ggtgcaggag cggttggacc gaacgctgcg ggccattgca
     1141 gtggaagccg aggcaaaggg atgggaacgc gttttggtgg tgtcacacgg aacggcggcg
     1201 ttaatgtggt tgaactatat ccactacaac attgatggcc gcgaaatgct ggataatgcg
     1261 agtgtcacca agttaatgtg gcttaatgac cgctttcggg tgacggactt caacgattta
     1321 agttttctgc atcatgggca agaagcgctg ggttaagccg tgcgttgcgg caatgttttc
     1381 tggtcgcgcc aaagcaacag atcaatcagg atcaacacca gcgtagcccc agccaaggcg
     1441 taggtgccga tagcgtgggt caggataccc gtgaccccgg caccaagggc aaaactcaag
     1501 atgatcgtac caacagtggc tgcggatgcg cggccttttt gttgtccgcg aataaagccg
     1561 tcatacaggc tctgcgcggc ggtgcgtaaa ttaccggtca tcattagtga ggtgaacgga
     1621 ccacctttta agcggcggaa ctcttgtaac tgagcagccg caatcactga aacgatagcg
     1681 ctggccaaca aatccggtag ccacttcccc aggaggctta ccaccaaaag ccatataatt
     1741 tcgtaacgga ggatccaccg ttgttcggca agcggttggg ggcgatgact ggcgtgtagc
     1801 tgcaaggcgc gtgcagccat ggtgccaaac ataaaggcga gaatgggtac cagatagcga
     1861 attgccgtgt accactgtcc ttggccaaga tggacgccaa gcaaaataac gttaccggtt
     1921 tgtaagcccg caaagacttc gccgtgcaac aagtaggtat acgcatcaaa actgccggca
     1981 gcagcagtga gcaaggtgcc gatgagcagg cgttcgtgaa tggggtaagt ggtggtttgc
     2041 atggttatgg tcgcctcgtt tgcttactat ttgattttat tctacgcaag tttggccagc
     2101 tgacaatgaa agtgactttt aagcttaaac cgttttgaag ttgatgtttg aaattaagtt
     2161 tgttctaagc tgaaaacggt ttgaccttaa acaaaaaatc ccggcgagca tagaatctac
     2221 tcgccaggaa agctttgttt gttttatgag ttgatgacta agtaaataat aacaaccagt
     2281 ttaggcacgg gtcatgcggc ctgaagctgg ctgaatgtga tctaagccat tattttttcg
     2341 gtcttcttct gtttctggtg gaaaggccaa gacagttccg ccgccaaggt tttttggtca
     2401 tagcgtggaa gtttgcaaca attttaaaat taagctctga cgcgttctga cggtcttgat
     2461 cagcgtagtc agtgatcgtc aagagtgccg aattttcgta gactttttcg attttaccgg
     2521 taaaaggggc ttccatgtct tctttaacct gacagaccac cgcgtcacca agatgtaatt
     2581 tttctttttc cataatgcct ccaacctttc ctgaattccc aacataagtg gcatactata
     2641 acaactgttg ctcaatatca aggtacaaaa ggtggaaagt ttcaaaaagt taaaaatatt
     2701 tatatgtttt ttgaacttag gcacttgact ttgatgcgta aggcacacca taacgcgccg
     2761 gctcacgctc ataaacgcgt tcacagtcgc agaaatctcc gtgtaaggac ctcagccgca
     2821 atggccaaag tcgggccatc acgtctgagg ccacttacac tccgatttct aagcgctcct
     2881 gttcacgctc ttccaccagt ttgctttcca aaagcaggta aaaagtggtt ataatggaat
     2941 aaaatagaaa ggacgaaatt agtcatggca actagcaaca caacgattga tcaattaaat
     3001 gaagcagcac aaaagacagc gcttgagact tttgctaagt tttacctgag tcggttcttt
     3061 ggtgacgggc ttgatgtttt ttctcaacta gatgagcaag gggatttggc ggatattaac
     3121 cactatcttc ttgataatcg cacgttgacg cgtgaggagt taacgagtgg gttactgaca
     3181 catcgttctg gcaacttgtt ggatcttttg aaacaggtca atgtcacatt caatgctcaa
     3241 ggggcgccgg aaacaccatg ggctaaatgg tatgccgatc aaattgaagg cttgccgcaa
     3301 ggactttaat caagcgtatg aagctgggtg ccattaagta gcgcattgtt ttcggacgat
     3361 ttttagatgg caggcagatc aggcttaaat cagccataga gacgaatcca gtttctatgg
     3421 ctgatttggt atcattagca ctttgatcta caacggctaa acggcaagca gcatggttta
     3481 cggacaagaa aggaacatta tgacgcaata tttaatcgtc agcgatattg acgggacgtt
     3541 gactgccaat catcatgacg tgaccgaaaa gacgacgcag gcaattgcca atgcggtaac
     3601 agccggagca gcgttttacg ttgcgacggg gcgcatgcat gcactggcag aagtggtagc
     3661 ccatcaattt caaccttatg ccaacattat tgcgtcaaat ggtgcggttt atgacttttc
     3721 cggtgagcgg gtgcatcaca cattgggtgc ggcggcgttg actgcggttg aggaagtggc
     3781 aaccgatctt ggactcaatg cgttgtattt cagcgatgac acggtttatt tcaccggaac
     3841 cttgccgcca gcgattgaag cagcagcacg gcggtttgca ccgagttcag tcgcgattga
     3901 ggtggttgcc ttaccctcag cagcggcatt attaacccac gccgcaacga tcacgaatgg
     3961 cattattttc ggaccgagtg actcacaagc attggtagct ggcaagaccg cattagaggc
     4021 acgcaacgtt ttgcatgtct ctgcgtctga acacacgaat ctggaattga ttcctaagta
     4081 tgtcgacaaa gccaatgccg tgcgtgaatt gcaggcgaaa accggcattg acgctgcgca
     4141 caccattgct tttggtgatg gcttgaatga cttagggatg ttgcaagctg ccgggatcag
     4201 tgtcgcaatg ggtaatgctg tgcctgaagt gaaacgcgtt gctcggtatg tcactgatac
     4261 taatgtggat gagggcgtgg cgaacttttt aacggatttc tttgagaagt gagctttttc
     4321 cgtaaaaagt ggggtttctg gttgattgtt agcgaaacgt ttgccaccat agagatggta
     4381 aacgttttta ttttgcggtc gtttgaggag ggcgttaatg atgtatcatg cagcagttga
     4441 tcgttatgag acaatgccgg ttcgccatgc tggtaagaca gggttgatgt tgccggttat
     4501 ttcgttggga ttgtggcagc attatggcaa cttggatcca tttggcccgc gacgctcggt
     4561 gattttggat gcgtttgatc gtggcgtttt tcattttgat gtcgctaatc attatggtaa
     4621 tggtgatcgt gaaccgggat ttggctctag tgaaaggtta ctcgggcaga ttctggccac
     4681 ggatttaaaa ccgtatcggg acgaattggt gattagtacc aaggtgggtt atgagattca
     4741 ccctggtccg tacggtgtcg ggacgtcgcg taaagcagtt attcaaggct tgaatgattc
     4801 actcaagcgc ttgcagttgg attatgtcga tatttactac gcacatcgat ttgacgatac
     4861 cgtggctttg gaagagacgg ttaatgcact ggatcaaacg gtgcgtgacg gtaaggcatt
     4921 gtatattggc atttccaact atgatacgaa gcagaccaaa gaagcaattg cgatgtttaa
     4981 agatctgcac acgccttttg tactgaatca atacagttac aacatgttta atcgcaccgc
     5041 tgaaacgtcc ggcttgatcg atgcattaaa agctgatggt gccgggttga ttgcatacgg
     5101 accgttatca gaaggcttgt tatcagatcg ctatctgaag ggaattccgg atactttcaa
     5161 aatccaccca accaatcaag ccacttttgc taagggcaaa gaggctgtgg ttaagcaact
     5221 aaatgcgctt aatgaaattg cgcgtgatcg tgaccaaacc ctgagtcaaa tggccttggc
     5281 gtggttgtta cgggatccgg ttgtcacaag tgtgatcatt gggacgacct cagttgaaca
     5341 ccttcaggat aaccttaaag caacggaaca tctgaccttt actgctgaag agattcagca
     5401 aattgatgat attttaaatg cttagttgac gtttggctgt aaaaggctaa gcgtaagtat
     5461 aaaaaacggc ttcggagtgt tttttgactc cggagccgtt ttatttttga ggaacaatgc
     5521 ttgacaggtg ctctcaatcc acatgaaaag cagcaagatg cgccgccaaa tattttgccg
     5581 tttctccatg accttgtttg gcaatggctt gcggcgtgcc ggctgctatg acgtgtccgc
     5641 cttctgcacc gccttttggt ccgaggtcca agacgtaatc agcgttggca ataacatcta
     5701 agtcgtgctc aatggcaatg acggtggcgc cggtttgcaa cagtcgctgg aacaccgcca
     5761 ccagggtctg aacatcgagc ggatgcaggc cgactgaagg ttcatcgaag acaaaaagcg
     5821 tgtctttttg cgagcgaccc atgtgggcaa caagtttgag gcgttgcgct tcaccaccgg
     5881 ataacgtcgg cgtgctttcg ccaaggtgta aatagcccag tcccatgtcg tgcaaggttt
     5941 gcaaggtgtg ggcgatggtc ggttcgtcct tgaaaacagt gagtgccgag tctacatcga
     6001 ggtcgagtaa atccgcgata ctccgctcgt gccatttgat tttcagcact tctggattgt
     6061 aacgtcggcc gtggcaggtg gggcaggttt gttgcatgtc cggtaaatac tggatgtcca
     6121 gattgataac cccggtgccg ccacaggttg ggcaggcgcc ggctttgaca ttgtaagaaa
     6181 aatggctgct ggtataatgc ttggccttag cagcgggtaa gccggcaaaa agatgccgca
     6241 aatgatccag aatatcggtg taggtggcga ccgttgagcg gacatttttg ccaaccggcg
     6301 ttgcatcaat ggcgaccaca tggcgaatgc caccggtttt tagatcgcgg acaaatgtag
     6361 ggccgggctg atctttggtt gcggaaagtg ccgggactag cgcatcgaaa atcaaggtgg
     6421 acttgcctgc accggagaat ccggacacca ccgagaaaca attaatcggg aattggacgt
     6481 tcagatgatg aagattaaac cgattcgtga ccgtgagctg cagttgcttg gctttggcaa
     6541 tgggcgcact gccggcttgc ggacggacga ttaaaggcgt tttgccagtt aaaaacggtg
     6601 cgattaacga attggtatcg tgacttactt cgaccggact gccttgatca agaatctggc
     6661 caccgtcagc tcccgcaccg ggtccgattt cgatgatttg atcggcggca ttgatgatgg
     6721 cggtgttgtg atcgacgacg actagcgaat tgccttgatc gaccaagcca tgcatgactt
     6781 ccaataaacc ggcgacattg gcagcgtgca aaccgatgga aggctcatca aggacataaa
     6841 gaacgccggt tgtttcggtg cgcaaggtgc ggctaagctg aatgcgttgc aattcgccgg
     6901 ttgaaagcga agcagcggcc cgactcaacg tgagataact taagcctaga tccatgatcg
     6961 gcttgagcag ttgggtcagc tctttgataa tatcgtgcgc caaggcttgc atgttagctg
     7021 gcagccactg gtaaattttc gggatgaaag cagttagttg tgtgagcgtc atgtcgctga
     7081 cttgggcgat gttttgatcg accagatgct gggctaacag tttgggtgcg aatcggctgc
     7141 cgtggcaggt cggacaaacg ccgaattcat agaagcgatt taaccgttca attgcccgtt
     7201 cgtttttggt ggtggctagc gaatctttaa cggcattaaa agcattttca tattgggcgt
     7261 gatccatgtg gaaaatcttg ccggttttgc ttggaatgtt gatcgcatat tttttgcgtt
     7321 ggccgtgcca gacctgttct tgctggtctt cgggtaagtc ttgaaaaggc gtgtcgatgt
     7381 caatgccgat tgcttgagcc acataaggca tgaagttgcg tcccggaagc cgccatgatg
     7441 ccacggcgcc ttggcgaatg gtcaaagttg gatcagggat gaggcgattg gccgcgagcg
     7501 tccgcgcctg acccgtaccg ccacaggttg ggcaggcacc ggtcgagtta aaagcaaaat
     7561 cctcagccgc aaatgccata aagtggacgc cgcatgtggg acaggtaatc atccccatac
     7621 cgctttcgcc atcattaggc agatccatcg ctttggcaat atcgagtgtc ggcggaacgc
     7681 ggtgaccatt gggacaaaca ggggagccca gacgcgaaaa catgaggcga ataacgttga
     7741 gggcttcagt tgcggtgccg actgttgagc gaattcccgg aaccacaggc cgctgtctga
     7801 gcgcaatggc actgggaata tgtttgactg aatctgccgc agccgggctg gtttggccta
     7861 agcgtcggcg agtgtaggtg gacagcgcac tcatatagcg gcgcatacct tctgcgtaca
     7921 gcacgcccat ggctagcgag cttttaccgg aaccggatcg gccggtgatc gcaacaagct
     7981 tatttaaggg aatatcgaca ttgagatgtt tcaaattatt cacatacgcg cctcgaacac
     8041 tgatatgatc tggaattgcc attgcaacac gctcctttgg cagacaaaac gtttcggtga
     8101 gtcagtttga aaaggctgat gagtttattg taacgcagct ggggaatagg ggtaagcgcg
     8161 agccggcgcg gttaggagtc ggagtgtgag tggccttggg cgtgatgacc cggtcctggt
     8221 cattgcgccc aaggtcctta cactccgact cctgcgccgg ggagcgcgtt atggcctttc
     8281 gccagtatgc atggcatcaa atttatcaga atatgccaaa aagccttacg cggtgatgcg
     8341 taaggcgtat gcgattttcc aaatatgggt gacgaactat tcttttaccg tgacgccggt
     8401 tgcttggctg agcagtttga tgagtttgag gtatttcttt tcacctaact cattgtacag
     8461 acgctcgagg ttgcctaaat attccggtcc taagtcctcg acagcctttt cgccggcttc
     8521 actcagcacg agtttgaaac tacggcagtc ttcgggatcg ggttgcttat cgagcaggcc
     8581 gcgttcgagc agtggaccgc ttgctttggt aatggcagcc ttggtgacgt gcatttcttt
     8641 agccagattc gttggtgttc gaggtgtcga atcggttgcc atccaaaaga gcagattttg
     8701 ttgattcaat ggaatgtcag ccgttgacac cggtgaaaaa agccgattaa attggttgac
     8761 cgactggctg gccgacaaat attgcttttt catcgtcatg ttcccccttt tttacataac
     8821 ctctttatac tttaagtatg aactcttgag gttaaggggc gcaacaatta gggcggataa
     8881 ctagttaaat tgttcatggc atcacattaa tttttgatga ttattaacta aggagtgttg
     8941 aagcgtgatt gactggcaaa tattgacggt atatgcgcaa aaagtttcat cacaggatca
     9001 tagcgggcat ggcttcgatc atattgaacg ggtggtggcg aatgcaaaac aactagtagc
     9061 caaaacagca ggcgttgatg caacggttgt cgtggctgcg gcaaccatgc atgatactta
     9121 tgacgataag ttggtggcag atgttggcgc agcaaaagca gccgcccagc aagcgatgac
     9181 cgcggccggg ttgacgcagg cgcagattca ggcagtgaca gaaattattg accacatgtc
     9241 gttcaaagca aatttaagca agcatcaacc gttatcagtg gaaggccagt tggtacaaga
     9301 tgcggatcgg ttggacgcga ttggtgcgat cggaatcggg cgcgcgttta tgtacgcagg
     9361 tgcgcatggc ggtcgcatgt atgatccggc actggcgcca agaacgaccc tgaccgcaag
     9421 cagctaccga ggaaaagata gcacggttat caatcacttt tatgaaaagc tattgaagtt
     9481 aaaggatcag ctcaatacat cagcagccag acagcttgct gagcatcggc agcaagtgat
     9541 gctgtcattt ttggacgaat ttaaagcaga gtggcgaagt acacgttaag ggaaaagtga
     9601 ccttaacgtg tacttcataa cttgtatgga gatagtgtgg agattgaagc ataatccgat
     9661 tattgtcact aaaactgctg ttaaatttgc ttattgcctt atttatgaat gaggtgtcag
     9721 ggctaaacta gaacgaggcg gcaattcagc tcgtaagtac tccgatcttg cagtcgccta
     9781 acaatgacag ctccacgtat gagcgctctg ccttgacaac aaggagattg ttaaagtcta
     9841 gctaattata ctaatccgga caaaataaaa gacttacctt ttttcatgaa aagggttaag
     9901 tctttgtttt gaaaggatga ttcatatccc atatcttaaa acaaaaagct ttttggaatt
     9961 cagcaagtgg tcttatggat tacaaaaagt ctaaaagatt ttagttacgt ttccaggggt
    10021 tatcgagaat cgtgttttgg ctatttatgg atactaagag actgtaaaat atacctgtct
    10081 cgccatataa gaatgaatga ctattgttga tgtacatatt attataagcc caacttaatg
    10141 ttcttccgta aggcgtagaa aggtctagca gcaatctatt gtgttgagtg tttaacggat
    10201 gattggcaga cacaatactt tctgcaagaa tcaggcccga gattccagaa tttacatcgg
    10261 gtgacccaag aaaggcgcta tcgcctaata attggtttgc taaagagtcc ttaaactgag
    10321 tcaccttgtc ctctctagta ctatcagcaa atagttggag aaatactaaa attcctaagt
    10381 ctcctttaga aagtccattc ttatgaatga gtgtggcatc ggtttcatac caaaaaagat
    10441 ttccaacttt attgatttgc acactttttc gtaatgatgt gtatatagct cgtgcggaag
    10501 ctaagatact tagttggcca gtgattaagt agtattgaat gaagaagatc ccaacaccag
    10561 ctaaaccata ctcaagatcc cgagttgatt cattttgagg gaatggtttc ttgggaccta
    10621 tatcaatggc taagacatct ttagaatgtg tgtaccgtcg actccaaatg ttcgtgtata
    10681 ctttttttag taaattaagg acagtttgct taaactttgt atctgaactc tgcatatatg
    10741 ctaagcaaag ggtaattcca attccggaca atccataata cattccgata gaataatcat
    10801 caaagttcgc ttcagaaagc tcaaaaagta agcgctctga tgtagaagtt gcttgagcca
    10861 gagtactaga actggtcaag gcttggtttt ttaagtactc gcatataagc agtagtgata
    10921 tgtctccatt aattagattg tggacatggg caggttcgtt tttccactga tcgtaaatta
    10981 aattgaagag attccctata tctccgggat agttatggct tcttttagcc agatcataac
    11041 gcatcattaa agcaatcaag gaaagcggcc cttggttaaa agatgaataa ttatgaacag
    11101 ggtatatgtt agttgcagat atgagatgta actgctgatc aatgtaatta tgtgacatgt
    11161 ttaatatttg tttgcgtagt gtgccggatg atatcctagc ctgtatgccg tgaactggag
    11221 tgtggattga gttgtcagaa gataacaagt caatgatatg agtccaggaa aagctcaagt
    11281 ttgacattat cttcactgcg agatttgcta ggaacctgtt tctttttgtt aagtttaaac
    11341 gatttattag agtatacatt tttgtgtata gtttgttcag agtgttatag tattcctctt
    11401 caaagattgg gactattttt gtcgatgcat agaatagcaa agaggcaaat gaaaatttat
    11461 cagaaagaat agacgctcgt tgaagtcgag ttcttatctg actgggaaga atgaatcctg
    11521 gcgttcctcc ttggaacgca tcaattcttc cagcgaaatc cgcaatttcg aaatcaataa
    11581 agtacggttc ctggtcggca tctatgagaa tattatttgg agataaatct ctaaaagcta
    11641 ttccagattt cgacagtatc ctcatttgat aggctatttt tttaaagacg gcagtcaagt
    11701 ttattttgga attgtcagct gtacaattag atattatttc gttaaatggg actccatgta
    11761 taagctgttc gattaggata gagcccccat ccgaattaat tgtgcgatat agctttggat
    11821 gattaaaact ttctggaaga gcttgcataa tctttgactc atgcaataag cgcgagacat
    11881 tacttctttc agtttcgtca aacaaacgat ttttcatagc aattttgatg attacttctt
    11941 ttccggcgta acgtccagaa aaaactgttg atcctactcg tttcctaact aattgaattc
    12001 ctgtgatatc tgcaggtaaa taaacagttt tgctcttgga ttcattgctt tctttattaa
    12061 gaaaggacgg tgtgttgatc cattctggct tatattgacc tattttctta atatcatcaa
    12121 tgagcttacc ttctttattg attatttgtg gaactacatt tcccctgtca tcaaatcgaa
    12181 aattttttcc aaagcttcca tatcttagaa atatttgtcc atctttgtac tgaatatcgg
    12241 tcacaacatc acaaaaactt gcatcattaa ggaattggtc taatgcgtta cacaatgcga
    12301 ataagcttgc cggctcttgg ctccttggat aaattgtgac ttctttcccc tgcattaagt
    12361 acccataaga tccgtaagat atttttaatg ctgtgtgcca ttttacggga actttaaatg
    12421 caaaatcaaa cttacttgct agttctccta ccttttctat tgttgatcct aaatgatttg
    12481 ggaggacaga taaatgaatc ttccaccctt gagcaggaag gaaattgaag tctctgatgc
    12541 agtaaaacca catttcatca tgatggaatc caaagccact tttcttcaag cttgtgattg
    12601 gcagtaactt taacagtgag tattccattt ttaatacctc cgtgggttgt catttcaaaa
    12661 accaaatgct attattaaat cgttctaacg ttagttcaat tctatctcat ttttttgaca
    12721 ttgacacgtc aggttttaaa tgcctaagga ggtattttta tgagtgaaga agtagcagaa
    12781 gaaacgttag ttactcgaac aggtctagct ctctccgaat tggataaact tgaaccgggt
    12841 gataccgact ttaatcacat tgtttttcga tctgtagacg gtggaagccc ttgtgaagat
    12901 gttggagcaa cagaactcat tccatattag tgtcgggtgt tgctagcaac atagtatgga
    12961 gcaaaagaat cccccaaagc acttggggga tttttagtat ttcgtctaag gattgcatca
    13021 ttatgtctac ataatgtgtt tgtcagcttt tttaaagggg ggtcatggct gtgacgtttc
    13081 gacaatatct tttccggctt aagtggcggt ttggcgtgtt tattttgatg tacggacttg
    13141 aaatttctgc gctaactgct gtgtcaattt ttactgggaa tatgattact gcgttgaccc
    13201 agtttaaagt aaatgccttt gtgactgctg cgattgtgat ggtggtagcg actatctttc
    13261 aactggtgat gcagacgctg accaatattt atcaggtgtc actacaacgg cggctcaata
    13321 atgacattcg taccgaaata acgaagagca ttgctgcgat gccgtttgaa cagtaccatg
    13381 cgcggtcgga tgcggtgtat acctcgtgga tgaccaacga tgtcaatacg attaataccc
    13441 agggactgcg caatgttggc tatctcattc aggcgagctg gcaagttgtg cttagtatct
    13501 ttgtgctatt gacctatcaa gcatcgttat ttgccaccac cttggtttgt gcagtgctat
    13561 tgatcacggt tccgatgatt tatcgtaaaa agctaagcgc tgcggcggca aaatggagtc
    13621 aggaaaacga gaaactgact aatcgaatta cggatattct tgaaggcttc aataccttat
    13681 ttatggcgaa tcgccgtcac gtcatggtgg atcgggtgtt tcatgcatcg aatgcggccg
    13741 ggcacgcaca agttgggtat attcaattca atatggccac gcaatttttg attaatttgg
    13801 tgaatctagg cagtcaactt ttcctgctga tccaagccgg attgctggca tataaccgcg
    13861 tgattccggt tggggcggtt gtcacaattc attcagtggc cgggacgact tttagtggct
    13921 taaccttgat gagttttgcc ctgaccacgg ttaaatcagt cgcaccgatt tttgataagt
    13981 ttgccaaggc gattccatca ccgcaaaaac cgaaagagcc agttaatggt ttggaagaag
    14041 gcattcatct gcaggatgtc actttcacct atccgcatcg caaggagccg gtacttaagg
    14101 atgtgacgat gacgttgacg gcaggtaaga aaattgccat tgtcggacca tccggccatg
    14161 ggaaaaccac cttgttgcga ctgattagcg atgtgctagc cgattatcaa gggcaaatca
    14221 cgtgggacgc ccaaaactat cagaagcttg atccgcgctc tttgcgggat cagattacct
    14281 atattgatca ggcaccttat atcttcaacg acaccattcg ctttaacttg acgctgggac
    14341 agcaggtggc tgatgatgtg ttgcagcatg cgattgaagc tgcgcggctg acaacgttta
    14401 tggcgcaaca ggaacaggga cttgatacgg tcttggaaca taatggggca gacttgtcag
    14461 gcggccaaaa acagcgaatt gccttggcgc gcggcctcat tcgccaaagc cacgtgatca
    14521 tcagtgatga aggcacggcg gcgcttgatc ctaagtcggg actcgccatc gaaaaattac
    14581 tggtggcgtt acccaagacc acattgatca tggtgaccca taaccttcgt ccggagatta
    14641 aagatcagct tgatcagatt gtaacggttt gaacccgttg acgttgctaa cagcttgaaa
    14701 tttgcagttg gaaaatggct tggtgcgata tttttccaaa aagggcttgc ggggaatggc
    14761 gatttagtgt acattaatta ggcagttgtt tttaaacaac caagtcattt gccgtcttag
    14821 ctcagtcggt agagcgcatc catggtaagg atgaggtcgt cggttcaagc ccgatagacg
    14881 gctgcaaatg aaatgcctga cagatagtta tctggtcggg ctttttttat tataagttgc
    14941 cagcaatgtt gtgacatcgt tatccgtcag tccaagtgac tgcctacgaa aggatcgttt
    15001 attttgcaaa tcctccgttc catcattcaa atttttggcg ttattgtcgg tttcttgttc
    15061 tactctctgg ccgaacttgc acttgttcgc agcgaactaa cctgggggat ggtcggtgcg
    15121 atcgcggcgt ttatcattgc attcggggca ttgattgccg ccttgatggt ttgttaccgg
    15181 cgcttatatc gccagcaatc gcctttaaaa gttgcccatc ccgttgcggt cgtcttgcag
    15241 ggcatcggct tactgctttt gattcaggtg acgaattcac tcattatgca gttaacccat
    15301 gcaccgttgg cagcaaatca gagtaatttg attaagctgg ttcatacgta tccatggggg
    15361 atcaagttgc tggcggtcgt cggtggtcct attgtcgaag aatatttatt ccgcggtctt
    15421 ttgatgaata gctttggttc attgcagaaa cgttcctggc agtgggttag cgtgttggtg
    15481 agtgcatttg catttggctt tgcccatgtg gcggggtcgc gcattgacta caatattttt
    15541 atttatgccg cacttggcgc tgtcttagct tggacctacc tgcgtacgcg ggacatgcgc
    15601 tattcaattg gtttgcacat actgaataat gcgacgattt tattggttta agcagcgtga
    15661 tcctaacaac cgatcattgc cgcgtgagct tccttggcta tgggcagatt ccgaattgct
    15721 aaaagcgtta atgaatgtat aaaaagccac c
//
