LOCUS       c00053_gnlPro..        13624 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LMPAEMNE_59.
ACCESSION   c00053_gnlPro..
VERSION     c00053_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 04:41:09
            Original ID  :: gnl|Prokka|LMPAEMNE_59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 10121
            Orig. end    :: 23745
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13624
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[20121:22943]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12822
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..13624
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13624
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             260..670
                     /locus_tag="ctg53_13"
                     /transl_table=11
                     /translation="LKTLIHLYKRYEMIINYLFIGGLTTLINFVTFFVMRYFDIGLVLT
                     NTTANIVSVIFAFFANKSVVFHSDYSSKKKFWFELTSFLILRGVSLLLDNFIMIVGVDW
                     LHGNEILVKILDQIIIVVANYLFSKLIFVRKR"
     CDS             complement(762..1283)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg53_14"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-28, bitscore:
                     90.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGLPAALAGQLSFPQRQVFNLAGDGAAAMVMQDLDTEVRYHLP
                     IINVVFSNNALGYIEDEQEDDGHEWFGVDMPAIDFATVAKGMGMTGLTVTKVSELAAAF
                     DEAEANRIAGKPTLIDAKITNERPIPVEHLQLDPDRFDAATIAAFKKRYYADNLVPFSS
                     FLAAHHVSVG"
     CDS             1314..1580
                     /locus_tag="ctg53_15"
                     /transl_table=11
                     /translation="LPTIHFQQAHSILGDIPDINRKNCIIGRNAVDLAKYRLKAHIASG
                     PLHHVIIVLMPIFDVIDIGLIPAAARSLITVGNHFLQSCGCIR"
     CDS             complement(1817..2374)
                     /locus_tag="ctg53_16"
                     /transl_table=11
                     /translation="VRHEEVGALAAVADGKLTGHIGVAFGSAGPGATHLFQGAYDAKMD
                     KVPTLFLVGQVEQRFMNADFFQELDEDPMFQDAAVYARTVTTAQSLPHVIDEAIRRAYA
                     AHGAAIVVIPNDLAAELIPANGYYSAAATHATPILAAGTDEQVDQALRLIRTASRPVMY
                     VGQGVRGAADTVMTLAKSYRCQ"
     CDS             complement(2707..3609)
                     /locus_tag="ctg53_17"
                     /transl_table=11
                     /translation="LTFYKKIIAALAMVATVGFLTACSSTQPKYDAKKPLGPQINYTIT
                     GIDAGAGIMSSTDKALKAYGLEEKNWQLQPSSTAAMTSTLQKAIADKRPIVVTGWTPHW
                     MFTKFPLKFLKDPKNVYGKAEQIHTIVRKGLKQDAPQAYQVLDQFHWTPKEISSVMLAV
                     NNGQDPAAAAKAYVKKHPEQIAQWTKGVSHVSGSPKLTLTYIAWDSEIASTNVVATVLR
                     QMGYKVTIRAMEPQPVWASVATKAADAQVSAWLPNTAAKLYADYKNQVVDLGVNMDGAR
                     VGLAVPKYMKNINSIEDLK"
     CDS             complement(3621..4067)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 72.2; E-value: 1.5e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg53_18"
                     /sec_met_domain="BPD_transp_1 (E-value: 6.4e-23, bitscore:
                     72.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFMQTMPAFVYLIPAVAFFGIGMVPGVVASVIFAMPPTVRMTQL
                     GIEQVPADLNEAAVAFGATSWQQLIKVQLPFARGTIMAGINQSMMLALSMVVIASMIGA
                     MGLGTKVYFAVGRNDAGGGFVAGLAIVILAIILDRITQSLNRTR"
     CDS             complement(4465..5688)
                     /locus_tag="ctg53_19"
                     /transl_table=11
                     /translation="MQHKIENDAETKIEVSGLTKIFGKRINRAKEMLKQGKTKAEILKA
                     TGATVGVDQADFTIKKGEIFVIMGLSGSGKSTTLRMLNRLIEPTAGQVLIDGDDIAKLD
                     KQHLREVRRQKLSMVFQGFALLPNRTVLQNAAFGLEIQGMDKSEREAKANKALDLVGLD
                     GFADQFPDQLSGGMQQRVGLARALASDAEILLMDEAFSALDPLNRRDMQDELLDLQEEM
                     HKTIVFISHDLNEALRIGDHIMIMKDGEIVQIGTPEEILSQPADDYVEKFIEGVDRSQV
                     YTAANVMIRANTVNIDKDGPRLAARRMRDNEISSLYVVNTKRQLVGILDADDVRAAIDS
                     GKKDLTTIVKTDVPTTKMDTPLADLLDAVSTTSVPYAVIDDQKRLRGIIIRGAVLGALS
                     GQEVNVNV"
     CDS             complement(6041..6772)
                     /locus_tag="ctg53_20"
                     /transl_table=11
                     /translation="MQYQNVSVGQLIRRVSRFTVELAIDGVTTSVHMNNTGRNKEILVP
                     GSLASVRYVNHPNRKTHYDLLAVNRQNRWINIDSLAPNHVARECLEAGTMKLPGLSLPY
                     AVRPETTWRDSRLDFAGTAADGQSWFVETKGVTLANQTLAAFPDAPTTRALKHVHTLTM
                     AQAAGYQAFLVFIVQLPNIQQMTIYRERFPELVTAITTAKQNGVRVLAYDTMTGPDFIT
                     LGQPILFDEHLPFTEMNLTSL"
     CDS             complement(7106..7567)
                     /locus_tag="ctg53_21"
                     /transl_table=11
                     /translation="LVTENDLTIESVHYNRLLLAIDDDDDDSSRKALNYACTVAKIYDI
                     PLGIVSVLETGDLNIFQSLTPEDVEAAREKMAKNLNTYVEKAREFGVQKAQPIIAEGRP
                     AAALLDEVIPAFKPDLVIMGSHVRRGRLRLGHVASEVARDAAVSVIIVR"
     CDS             complement(7616..8875)
                     /locus_tag="ctg53_22"
                     /transl_table=11
                     /translation="MKDTPSFTPILLGSDMNVYGMARSFHEMIGGAIDVYAREQLAPTR
                     FSRIVNVHLIKQFDSDPTFIEKMREVAHLHAASAGRLLLIACGDTYAQLVSKHKDELSQ
                     WFICPYVDYDLLKRLNSKESFYQVCEEYHLPYPATKIVTKSMYESNATITAPFEFPVAL
                     KPTDSVEWLNIHFEGRKKAFTIHSQVELTNTIAKIYDNGYTSDLILQDFVPGDDSNMRT
                     LNCYVDQYHHVKMMCLGHPLLEDPTPASIGNYVAIMPAFDQTLYDQIKEFLEAIKFTGF
                     ANFDMKYDHRDNTFKLFEINIRQGRSSFFVTLNGYNLASWPVRDYITGDLKNAPTVYGN
                     SDRSKYKLWLGVPERVFKQYSADNEAKREALKLIKEKRYGTTVFYKPDMTLKRWLLLKY
                     MFHNYVGRFKQYFAENKGDV"
     CDS             complement(9157..10035)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg53_23"
                     /sec_met_domain="GHMP_kinases_N (E-value: 2.7e-16,
                     bitscore: 50.5, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISVSVPATSANLGVGYDVLGLALDLKARFTFEASTQKLEIFGDD
                     PDFANEHNLIYQAFVTFAKAVDQPVPNLRITVDSNIPSSRGLGSSATCVVGGIAAANAW
                     FHAGWDRTQLLKLAAKMEGHPDNAAPAIFGQLCATILADAEPIVRQYPVSSQLQLVTFI
                     PDYAVSTAEARKILPTTMTYADAAYQMGRCVLMTRALADGDLPLLHQVAHDRMQEPYRA
                     TLIPDYQAVRQLVTAANGVLLISGSGSTMLAIVEGAAAARQLQAAASQQWPAWRVQIVQ
                     PSTEGVRVSES"
     CDS             complement(10001..11515)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_24"
                     /sec_met_domain="PALP (E-value: 4e-15, bitscore: 46.7,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYTSTRDQRVSKTGQQAIKQGISEEGGLFVLPHLTDYRLNLQNL
                     LGKDYETIAQNVLTTLLPDFNTAALKKAIQFAYHKNFSDRRLTPVRSVGDFHVLELFHG
                     PTSAFKDLGLQLLPQLMRLALDPEDRIMILAATSGDTGTAALQGFKNVAQTGITVFYPD
                     HGVSPIQERQMLTTTGNNTRVFPIGGNFDQAQSAVKDLFTDTGFAARLQAEQVTLSAAN
                     SINIGRLIPQVVYYFSAYLQLVESGAIELGQKVNFTVPTGNFGDVLAGFYAKLMGLPIH
                     QLIAAANANHELADFLETGIYDRNRPFLKTVAPSMDIQISSNLERLLYYKSGEDSSYVA
                     KLMEELATTGRYQVRPDVLAAIQADFAGGFAADAQIAASIAAVWKQNDYLLDPHTAVGY
                     HVMQQYRETTGDSTPNVLLATASPYKFPRAVAQALDLPVTGDDFAVMTQLHQMSGVPIP
                     ANLARLATLTAQPKHVVAPEEMGQAIIAAAKEVFNNDQRVRSGNKR"
     CDS             11623..12822
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: Homoserine_dh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_25"
                     /sec_met_domain="Homoserine_dh (E-value: 2.3e-49, bitscore:
                     158.4, seeds: 932, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIAILGFGTVGSGVYDIVENGDRRMRVTAIFIRPTHPATMPEMT
                     TNFDAILADPNIDVVVEAIGGLHPAYDYILRALQHGKHVVTANKAVVAQHLPEFITTAA
                     QHHVRFYFEATTGGGIPWIRNLERAARIDQIDTIEGIFNGTSNYILDQMQRAHLDFDPV
                     LLAAKDMGYAEADPSADIDGDDVVNKLKISAALAYDMVPPRDVPKFGIRNVTKADIDFF
                     ASRHQVLRLIGKSRRVGNHYSMVVEPRLYPATALAANTFENFNLIRLHGQTIGDLQFYG
                     QGAGKYPTANAIVQDLFDILENAPHLTRHFDQNLQFDADLNTADYLLRADPITFAMFND
                     KDTEVVRDHLLIKQIPTGEMHRLMRGVLAIDAHAFMAAIGDSELTTRNVKEQVDQGVIE
                     "
     CDS             12819..13622
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg53_26"
                     /sec_met_domain="AA_kinase (E-value: 3.8e-41, bitscore:
                     132.0, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVKFGGSSVADAGQFQKVKAIINQDPQRQIVVISAAGKYGDAT
                     RKLTDTLYLIADGFEAGRDVTPLFAQVAARLEAINQALHLHVPLIKLMNTIRHHIATHY
                     SRDYLVSRGEFLTAQLMAAYLGYTFVDAADLLFFDQNGAIDEAKTLAAYRRLPRHHGIV
                     VPGFYGQNAAGHVQIMARGGSDISGAWLARLAQADLYENWTDVSGIKMADPRIIQDADS
                     IDVMSYDELRELTYMGFSVFQEEAVQPVRESGIPTRILNTNVPEDP"
ORIGIN
        1 tgagattcaa gcaggcccat gacacccaag tctcagcctt tcgctaacaa attgtaagtc
       61 aattaggcgg ataaacgcaa gtcaacagct cagtcgtttt tttagctgcg cactgacaag
      121 ggttatcgtt aatgtcagtc tcgcatgaac cttataaaaa gcatctcact accactcagc
      181 ttgcatggta tactgacacc attcgtgcgc agccaaacac tgcattgcat caaactcaaa
      241 gctaggagag atttaacctt tgaaaacgct gattcatcta tataaacgct acgaaatgat
      301 catcaactac ttatttatcg gtggactcac caccttgatc aatttcgtca ccttttttgt
      361 gatgcgctat tttgatattg gcttggtctt aaccaacacg accgctaaca ttgtcagtgt
      421 catttttgca ttcttcgcca acaaaagtgt cgtcttccac agtgactatt caagcaaaaa
      481 gaaattctgg ttcgagctaa ccagttttct aatcctccgt ggcgtttcac tgttgctgga
      541 taacttcatt atgattgtcg gcgtggactg gcttcacggc aacgagatcc tggtcaaaat
      601 tctggatcaa atcatcattg tcgtcgctaa ctacctgttc tcaaaactga tctttgtccg
      661 caaacggtag ctatgcttat cgagttctag attgttaact aaaacgtgcc ccaaaagtaa
      721 aaaccgcttt tggggcacgt ttgcgttttc atcaatcaaa ttcaacccac cgaaacatga
      781 tgcgccgcta gaaacgaact aaacggcacc aaattatcag cataataacg tttcttgaag
      841 gcagcaattg tagcggcatc gaaacgatcc ggatctaact gcagatgctc gaccgggatt
      901 ggccgctcat tcgtaatttt ggcatcaata agtgttggct tgccagcgat gcgattggcc
      961 tcggcttcat caaacgcagc cgcgagttcc gaaaccttgg tgacggtcaa accggtcatg
     1021 cccattccct tggcaaccgt tgcaaaatca attgctggca tatcaacgcc aaaccattcg
     1081 tgtccgtcat cttcttgctc atcttcaata taacctaatg cattatttga aaaaacaaca
     1141 ttgataatcg gcaggtgata ccgcacttct gtatccagat cctgcatgac catcgccgcg
     1201 gcaccatcac cagcaagatt gaacacttgg cgctgaggaa aactcaactg tccggctaag
     1261 gctgccggca atcctgcacc catcgtggcg aacagtccgc tggttgtcca cgcttgccga
     1321 ccattcactt tcaacaagcg cacagcattt tgggtgacat ccccgacatc aatcgcaaaa
     1381 attgcatcat cggtcgcaat gcggttgatc tggccaaata ccggctcaaa gcgcatatcg
     1441 ccagtggtcc gttgcatcat gtcatcattg tactgatgcc aatttttgac gttatcgaca
     1501 ttggcctgat accagccgct gctaggagcc tcatcactgt gggcaatcat tttcttcaaa
     1561 gttgcgggtg catccgctaa gattgccaca tctgtgtgat gccgcttgcc taaggttttg
     1621 ggatcagctt cgatttgaat aaacttggct ttaggcgaaa acataacttc cgcaaatgga
     1681 taattcgagc cgacaaacat gatcaaatcg gccacccgca atgcttcatt ggccggtttc
     1741 gatgcgaccc gtgcagccga acccaagagt gcttcaaagg cgtacggaat aatcggcttg
     1801 cccagcgctg tcgttatcac tggcatctgt aacttttggc tagcgtcatc accgtatcag
     1861 ctgccccgcg aacgccttga ccgacataca tcaccggccg agacgcggta cgaatcaatc
     1921 ttagtgcctg atccacctgt tcatcagtgc cggccgctaa aatcggggtg gcatgggtcg
     1981 ccgcggcact gtaataccca ttcgccggaa tcaactcggc ggccaagtcg ttaggaatca
     2041 ccacaatcgc cgcaccatga gcagcatatg cccgccgaat cgcctcatca atgacatgcg
     2101 gtaaactctg cgctgtggtg acggtacgtg catagacagc cgcatcctga aacattggat
     2161 cttcatctaa ttcctgaaag aaatcagcat tcataaaccg ttgttccact tggcccacta
     2221 agaacaaagt aggcacttta tccattttgg catcgtaagc gccttggaaa agatgcgttg
     2281 ctccggggcc agctgacccg aacgccaccc caatatgacc cgtcagcttt ccatcggcga
     2341 ccgctgccaa ggccccgact tcttcatggc gcacatgaat atacttgatg cgcgactttt
     2401 cctcatgcaa cgcgtacatc atgttattaa atgtgccacc ggggatgccg taaatgtgcg
     2461 tgacgcccca actctccaaa gtttgtagcg ctgcaacccc agctttaatc gtctcaacca
     2521 tcataagtcc cccttttatt taaaaaccgg caatctgaac ctgccagttt tggcgtgtta
     2581 ttaaagctgc ttccgcggtt atactaggca cgaaaagatg agaaagcaaa tcatctgcct
     2641 atgtaaaaac gccaaggata tgatccgtct tcatgacgaa ccgtaccctc agcgttttaa
     2701 tgatggttac ttcaaatctt caatgctatt gatattcttc atatactttg gaacggccaa
     2761 accgacccga gcgccatcca tattcacgcc aagatcaaca acctggttct tataatcggc
     2821 gtataacttg gcggcagtgt ttggcaacca cgccgatacc tgtgcatctg ctgctttagt
     2881 cgcaactgat gcccaaaccg gctgcggctc catcgcgcga atcgtcactt tataacccat
     2941 ttgccgcaaa acggtcgcca caacgtttgt ggaggcaatt tccgaatccc aggcaatata
     3001 ggtcagggtt aatttaggac taccgctaac atgactaaca cccttagtcc attgagcaat
     3061 ttgctccgga tgtttcttca cgtatgcttt tgcagctgca gcaggatcct ggccattgtt
     3121 caccgccaac atcacactag aaatttcttt gggcgtccag tgaaattgat caagcacctg
     3181 gtaggcttgc ggagcatctt gcttaagccc tttacgcaca atcgtatgaa tctgttcggc
     3241 tttaccatag acattcttag gatccttcaa aaatttcaac ggaaacttgg tgaacatcca
     3301 gtgcggcgtc cagccggtca ccacaatggg ccgcttatcg gcaatcgcct tttgcagtgt
     3361 actggtcatc gccgcggtcg agcttggttg caactgccaa ttcttttctt ccagtccgta
     3421 tgccttcaag gccttatcgg tactgctcat gatgccggca cctgcatcga ttccggtaat
     3481 cgtatagtta atttgcggcc ctagaggctt tttggcatcg tacttaggtt gggtactgct
     3541 gcatgcggtc aaaaagccaa ccgtggctac catcgccagt gccgcaatga tttttttata
     3601 aaaagtcaaa cagccacctc ctagcgcgtg cgattgagac tttgggtaat ccgatccaga
     3661 atgattgcca gaataacaat cgccaaaccg gcaacaaacc cgccgccagc gtcgttacga
     3721 cccacagcaa agtaaacctt ggtacctagg cccattgccc cgatcatgga tgcaattacg
     3781 accatggata aagccaacat catactttga ttaatgccgg ccataatggt gccgcgggca
     3841 aagggcagct gcactttgat cagctgctgc caactcgtag caccaaatgc aacggctgct
     3901 tcattcaagt cagctggtac ctgttcaatt cccaattgcg tcatccgaac tgtcggcggc
     3961 atcgcgaaaa tgactgacgc aacaacgccg ggaaccatcc cgataccaaa gaatgccacg
     4021 gcgggaatca aataaacaaa ggctggcatg gtctgcataa agtccatcaa cggcttgaca
     4081 atcgccgaaa cggttttact ttcagcagcc cagataccca gtggaatgcc gatgacaatt
     4141 gccaacaagc ttgcggtcag aaccaaggtc agcgtctgcg tcatatcgcg ccaaaatccc
     4201 agattccaga ttaacaacag ccccactaat tcgaaaatca gcaaactgcg atacttctgc
     4261 cctcgcttaa ggtaccaagt cagcgccata attaagatga taaacagcca aatcggaatg
     4321 aaatcaaaga ccgcttgaaa ggcattgaca atcgttccga taaagttcgt cagcacaccg
     4381 aagaacccgg caaattgagt gagccagtcc acgaaggaat caatccaatg tgctaatggt
     4441 aacgttggga tggtaactaa aagattaaac attgacattg acctcctgtc ctgagagtgc
     4501 gccaagaacg gcaccgcgaa tgataatccc gcgaagtcgt ttctgatcat cgatgacagc
     4561 atacggaact gaagtagtcg acacagcatc cagcaggtca gctaacggcg tatccatttt
     4621 tgttgtcggt acgtcggtct taacaatcgt ggttaagtcc tttttcccgc tatcaatggc
     4681 cgcacgaaca tcatcggcat ccaagattcc tactaattgt cgcttggtgt tgacaacata
     4741 caagctggaa atctcgttgt cacgcatccg ccgtgctgcc aaacgcggac catccttgtc
     4801 gatattcacg gtgttagcgc gaatcataac attagctgcg gtataaacct gactccgatc
     4861 cacaccttca atgaacttct caacgtaatc atcagcaggt tgactcagaa tctcttctgg
     4921 cgtcccgatt tgaacgatct cgccgtcttt cataatcatg atgtgatcgc caatccgcaa
     4981 cgcttcattc agatcatggg atatgaaaac aatcgtcttg tgcatttctt cttgcagatc
     5041 caacaattcg tcttgcatat cccgccgatt taacggatca agcgcagaaa aggcctcgtc
     5101 cattaagaga atctcggcat cactggccaa cgcgcgcgcc aagccgacac gttgttgcat
     5161 cccgccagat aattgatcag gaaattgatc ggcaaacccg tctaatccca ctaaatcaag
     5221 cgctttgttg gctttagctt cacgttcgga tttatccatc ccctgaattt ccaagccaaa
     5281 cgccgcgttt tgtaaaacag ttcggttagg caatagcgcg aagccttgaa ataccatgct
     5341 cagcttttgc cgccgcactt cacgcaggtg ttgcttgtcc aacttggcaa tatcatcacc
     5401 atcaatcaga acttgtccgg cagtcggttc aattaaccga ttcagcattc gcagtgtggt
     5461 tgatttaccc gaaccagaaa gccccatgat aacgaagatt tcaccttttt taatggtgaa
     5521 atcagcttga tcaacaccca cggttgcgcc cgtagccttt agaatctcag ccttggtttt
     5581 cccttgcttt aacatttctt tggcacgatt gattcgtttg ccaaaaatct tggttaaacc
     5641 actcacttcg attttggttt cagcatcatt ttcaatcttg tgttgcattt gctcactcct
     5701 ctcaggcccc ttaacgaatt aagatatcgc cttggtgccc ggtacttttt aaaatcgcta
     5761 cttacctgat gttgcgattt tgttctgttt cagaaacagt tgtcatcgaa ttgaaacaat
     5821 gctaaccatt gtacgagtca tttgtgtgtg attcaaatca cggaatctca ttttcatttt
     5881 caagacacgc tggcgttttc acttgctgaa aattttagcc acaacaaaaa agccctcatc
     5941 ggcataggat tgagggctag ggacgattga tgacccgcta atcgtgcatc gtaatcgttg
     6001 tcaagttaat atgaaaatat catgaccgaa ttctcatatt tcacaaactc gtcaggttca
     6061 tttccgtaaa tggcagatgc tcgtcaaaca ggatcggctg gcccaaagta ataaaatccg
     6121 gacccgtcat cgtgtcataa gccaagacgc gcacaccgtt ttgcttggca gttgtgattg
     6181 cggtgacaag ctctggaaac cgttcacgat aaatcgtcat ttgctgaata ttgggtaact
     6241 gcacaataaa aaccaaaaat gcctgatagc ctgccgcttg ggccattgtc agcgtgtgca
     6301 catgcttcag cgctcgcgtg gtgggagcat cgggaaacgc cgccaatgtt tggttggcta
     6361 atgtgacgcc tttagtttca acaaaccatg attggccatc agccgcagtt cccgcaaaat
     6421 caagccggga atcgcgccag gtggtctcgg gacgaaccgc ataaggcaag gataatccgg
     6481 gcaatttcat ggtgccagcc tccaagcatt ctctggcaac gtggttgggg gctaagctgt
     6541 ctatattaat ccaacgattc tgccggttta ccgcaagcag atcatagtgc gtcttccggt
     6601 tgggatgatt cacataacgg acactggcca gcgaacccgg cactagaatt tccttattcc
     6661 ggccagtgtt gttcatatgt accgatgtcg tcacgccatc aatcgcaagt tcaaccgtaa
     6721 accgactcac gcgccggatc agttgcccga cactgacatt ttgatactgc ataaacgctc
     6781 ctcatttcga ttttgcctga caggtagcat agtgcttatt aaccgcgctg acttatgctc
     6841 ataacgtgtt tgctggcgca gggatttgcg tgtaaggacc ttggttgcag tggccactta
     6901 tgttctggtt tacgcccata acgcgctccc cggcgcagaa gtctgcgtgt aaggacctca
     6961 ggcgcaatgg ccaaagaccg gccatcacgc ctgaggccac ttacactccg atccctaaac
     7021 gcgccggctc gcgctcacac aaaaatagca gccgcggact ttaatcaaat ctcacggctg
     7081 cttatttgaa tcatagcact gacaattaac ggacaataat aacggatacc gctgcatcgc
     7141 gggctacttc gcttgcaacg tggcccagtc gcagacggcc acgacgtacg tgtgaaccca
     7201 tgataaccaa gtccggcttg aacgctggaa taacctcgtc aagcagtgcc gctgccggtc
     7261 gaccttcagc gataatcggc tgggccttct gcacgccaaa ctcacgggct ttttcaacat
     7321 aagtattcag gttcttcgcc attttttccc gtgctgcttc aacatcctca ggcgtcaatg
     7381 actgaaaaat attcagatcg ccggtttcaa gcaccgatac aatccccagc ggaatatcat
     7441 agatcttggc aaccgtgcag gcgtagttca atgccttgcg cgaggagtcg tcatcatcat
     7501 catcaatcgc caataacagc cgattataat gtacggattc aatcgttaaa tcattttcag
     7561 taaccaaaag aaatgccccc ttgcaagttt aggtgtccct aacatgttta ttttatcaca
     7621 catcgccttt gttttccgca aaatactgct taaagcgacc aacataatta tgaaacatat
     7681 atttcagtaa tagccagcgt ttaagcgtca tatctggttt gtaaaagacc gtcgtcccgt
     7741 agcgcttttc tttgatcaac ttcaacgctt cccgcttggc ctcgttgtcg gcggagtatt
     7801 gcttgaagac ccgttcaggc accccaagcc ataatttgta cttgctgcga tcggaattgc
     7861 cataaacagt cggcgcattt ttgagatcgc cggtgatata atcgcgcacc ggccagctgg
     7921 caagattata gccattcagg gtcacgaaaa agctgctgcg accctgccga atattaattt
     7981 caaataactt aaacgtgttg tcgcggtgat catacttcat atcaaagtta gcaaaaccgg
     8041 taaacttgat ggcttcgaga aattctttga tttgatcata caatgtctga tcaaaagccg
     8101 gcataatcgc cacataattc ccgatggacg ctggtgtggg atcttcaagt agcggatgac
     8161 ccagacacat cattttgaca tgatgatatt ggtccacata acaattcaac gtccgcatat
     8221 tgctgtcatc acccggtaca aagtcttgaa gaattaagtc agatgtatac ccattgtcat
     8281 aaatcttggc gatggtgttg gtcaattcga cttgggaatg aatcgtgaat gcctttttac
     8341 gcccttcaaa gtggatattc aaccattcca ccgaatcggt cggtttcagc gccactggaa
     8401 attcaaatgg cgccgtaatt gtggcgttgc tttcatacat tgacttggtc acgatcttag
     8461 tggctgggta aggaagatgg tattcttcac aaacctggta aaagctttcc ttactgttaa
     8521 ggcgttttaa aagatcatag tcaacatatg gacagataaa ccactgactt aattcatctt
     8581 tatgtttgga taccaattgt gcatatgtgt caccgcacgc aattagcagc agacggccag
     8641 ccgaagccgc gtgcagatgc gcaacttcac gcattttttc gataaaagtc gggtcagaat
     8701 caaattgctt aatcagatgg acatttacga ttcgtgaaaa gcgtgttggg gccagctgtt
     8761 cacgcgcata gacatcaatc gccccgccga tcatctcgtg gaacgaacgc gccataccat
     8821 acacgttcat atcactgcca agcaggatgg gggtaaaact aggtgtatct ttcatctgaa
     8881 tgataatctc ctcgttcgat taggtgcggg caaaagaatg ccgggtacca tgaaattttc
     8941 attgaaagtg cagtggcaag ttgtctcagc gggtccaaac tgcactaata attttccctg
     9001 agcggttggt caaaatgaat attgccttca gctcgtcgcc ccagaattat accatactgg
     9061 caatctgcat tcatgaagat actaatagga taacagtttt tcaagattta gacgcaaaaa
     9121 cgccaagtgt cagggcttgg cgttttttga tattgttcag ctttctgaaa cccgcacccc
     9181 ttctgtactc ggctggacga tctgcacgcg ccatgctggc cattgttggc tggcggctgc
     9241 ttgcaactgg cgagcagccg ctgctccctc aacgattgca agcatggtcg atcctgaacc
     9301 cgagatcaac aaaacgccat tggctgcggt aaccaattga cggacagcct gatagtccgg
     9361 aatcaatgtg gcgcgataag gctcctgcat ccgatcatgg gccacttgat gtaaaagcgg
     9421 taaatcacca tctgccaacg cccgcgtcat tagaacacat cgtcccatct gataagcagc
     9481 atctgcgtaa gtcatcgttg taggaaggat ttttcgtgct tctgcagtgc tcacagcata
     9541 atcagggatg aatgtcacta actgcaactg tgagctgacc ggatactggc gcacaatggg
     9601 ctctgcatct gccaaaatag tcgcacacag ctgaccaaaa attgcagggg cagcattgtc
     9661 cggatgccct tccattttcg ctgcaagctt caaaagctga gtccgatccc agccggcatg
     9721 aaaccacgca ttcgccgcgg caattccgcc aacaacacac gtggccgaac ttcccaagcc
     9781 gcgcgaacta ggaatgttcg aatcgaccgt aatccttaaa tttggcactg gttgatcaac
     9841 cgctttggca aatgtcacaa atgcctgata aatcaagtta tgctcattgg caaagtcggg
     9901 atcatcccca aaaatctcaa gcttttgggt gctcgcttcg aaggtgaacc gagctttgag
     9961 atcaagggct aatcctaaaa cgtcataacc aacgcctaaa ttagcgcttg ttgccggaac
    10021 ggacacgctg atcattgtta aaaacctcct ttgcggctgc aatgatcgcc tggcccattt
    10081 cttccggcgc caccacgtgt ttaggttggg cagtcaaagt tgccaagcgc gctagattag
    10141 caggaatcgg aacaccactc atttgatgca actgggtcat cacagcaaag tcgtcacctg
    10201 tcaccggcaa gtcaagggct tgagcaaccg cgcgtggaaa tttgtatgga ctagccgttg
    10261 cgagtagcac attaggggtc gaatcaccgg ttgtctcccg atattgctgc atcacatggt
    10321 agccgacagc cgtgtgagga tccaacaaat agtcgttttg cttccaaacc gcagcaattg
    10381 aagctgcaat ctgtgcatct gcggcaaaac cgccagcaaa atcagcctga atcgctgcca
    10441 aaacatcggg ccgtacctga tagcggccgg ttgtggccaa ttcttccatt aatttagcca
    10501 cataactgct atcttcacca ctcttatagt agagtagccg ttccaagtta ctggaaatct
    10561 gaatatccat acttggcgcc accgtcttta ggaacggacg attgcgatca taaataccgg
    10621 tttcaagaaa gtccgccagt tcatggttgg cgttggccgc ggcaattagt tgatgaatcg
    10681 gcaaccccat taacttcgca tagaaaccag ctaggacatc cccaaagttg ccagttggaa
    10741 cagtgaaatt aaccttttga ccaagctcaa tggcacctga ttcaaccagt tgcaagtagg
    10801 cggaaaaata ataaaccacc tgaggaatca aacgcccgat attaatcgaa ttggcggccg
    10861 aaagcgttac ttgttccgcc tgcaaacgcg ccgcaaaacc ggtgtcggta aagagatctt
    10921 taacggcact ctgcgcttga tcaaagttac cgccaattgg gaaaacccgt gtgttattgc
    10981 cggttgtcgt taacatttgc cgctcctgaa tcggactaac cccatgatca ggataaaaga
    11041 cggtaatccc ggtttgggcg acatttttga acccttgcaa cgccgcagtc ccggtatcgc
    11101 cactggttgc ggctaagatc atgatgcgat cttccggatc cagtgccagg cgcatcagtt
    11161 gcggtagtag ttgcaacccc aagtctttaa aggcgctggt tgggccatga aacagctcta
    11221 aaacatgaaa atcacccaca gaccgaacag gcgtcagccg gcgatcagaa aaatttttat
    11281 gataggcaaa ttggatcgcc tttttcaacg cagcagtgtt aaaatcaggc aacagggtcg
    11341 tgagaacatt ctgagcaatc gtttcataat ctttacctaa taaattttga agattcaagc
    11401 ggtaatccgt tagatgcggt aaaacaaata acccgccttc ttcggagatg ccttgcttga
    11461 tcgcttgttg tccagtcttg ctaacgcgct gatcccgtgt acttgtgtat cgcatgtgaa
    11521 cgactcctat ctgatccgac ttgtttttgg aataaggata tgataatctg ttcgcattag
    11581 aaaaacaagt gtctatattt tatatacaag gagctgaaga aaatgaatat tgccatctta
    11641 ggttttggta ctgtcggtag cggcgtttat gacatcgttg aaaatggtga tcgccgaatg
    11701 cgggtcactg ctattttcat tcgcccaacc cacccagcta cgatgcctga gatgacaaca
    11761 aatttcgacg ctatccttgc tgaccccaac attgatgttg tcgttgaggc tattggcggc
    11821 ttgcatcctg cttatgatta tatcctacgt gcactgcagc acggtaaaca tgtggtgacc
    11881 gccaataaag ctgtcgttgc gcaacacctg cctgaattca tcacaacggc ggctcagcat
    11941 cacgttcgct tttattttga agcaactact ggtggcggca ttccctggat tcgcaatttg
    12001 gaacgtgctg ctcgcattga ccaaattgat accatcgaag gcatctttaa tggtacgagt
    12061 aattatattc tggatcaaat gcagcgggcg catctcgatt ttgacccggt tttgttggca
    12121 gctaaagaca tgggttatgc cgaagccgat cccagtgcgg atatcgacgg tgatgacgtg
    12181 gtaaacaaac tcaaaatttc ggccgccttg gcttacgata tggttccgcc gcgcgatgtt
    12241 cctaagtttg gcattcgtaa tgtcaccaaa gccgatattg actttttcgc cagtcgtcat
    12301 caggttttac gactaattgg caagagcaga cgggttggca accattatag tatggtcgtt
    12361 gaaccgcgcc tttatccggc gactgctttg gcggctaaca cgtttgaaaa cttcaacctg
    12421 atccgactgc acggccagac cattggcgat ttgcagtttt atggtcaagg cgccggtaaa
    12481 tatccgactg ctaatgccat tgttcaggat cttttcgaca ttctggaaaa tgccccgcat
    12541 ctgacgcggc actttgatca gaacttacaa ttcgatgcag atctgaatac tgctgattac
    12601 ttgctgcgag ccgatccgat cacgtttgcc atgtttaacg ataaagacac cgaagtcgtt
    12661 cgggatcatc tcttaatcaa acaaatcccg accggcgaaa tgcatcggct catgcgtggc
    12721 gttttggcaa ttgacgctca tgccttcatg gcagccattg gcgatagtga actgaccacc
    12781 cgtaacgtta aagaacaagt tgatcagggg gtaatcgaat gaaagtcgtt aaattcggcg
    12841 gtagttcggt tgccgacgcc gggcagtttc aaaaagtcaa agccattatc aaccaagacc
    12901 cgcagcgcca aatcgttgtc atcagtgcag ccggtaaata tggcgatgca acccgcaagt
    12961 tgactgatac cctttatctg attgcggatg gattcgaagc cggtcgtgat gtcaccccgc
    13021 tttttgctca agtggcagcc cgactggaag ctatcaatca ggctttacat ttgcatgtgc
    13081 cgctcataaa actcatgaat acgattcgtc atcacatcgc cactcattac tcgcgcgatt
    13141 atctggtttc gcgcggtgag tttttaaccg cccaactgat ggctgcctat ttgggctata
    13201 ccttcgttga tgctgctgat ctcctctttt ttgatcaaaa cggggcgatt gatgaagcca
    13261 aaacattagc tgcttatcgg cggctaccgc gtcatcatgg gatagttgtt cccggattct
    13321 acgggcaaaa tgctgccggt cacgtacaaa tcatggcgcg cggcggttcc gacatttccg
    13381 gtgcgtggtt ggcgcggctg gctcaagctg atctttacga aaattggacc gatgtttccg
    13441 gaatcaaaat ggccgatccg cgaattattc aagatgccga tagtattgac gtaatgagtt
    13501 atgatgaatt gcgcgaattg acctacatgg gcttcagtgt ttttcaggaa gaggcggtcc
    13561 agccagtgcg agaaagtggc attccaactc gcattcttaa cacgaacgtc ccagaagatc
    13621 ccgg
//
