LOCUS       gnlProkkaIHBLKMDC_22   24458 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IHBLKMDC_22.
ACCESSION   gnlProkkaIHBLKMDC_22
VERSION     gnlProkkaIHBLKMDC_22
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 04:10:19
            Original ID  :: gnl|Prokka|IHBLKMDC_22
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 29147
            Orig. end    :: 53605
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24458
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14458]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14458
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..24458
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..24458
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             429..1946
                     /locus_tag="ctg22_26"
                     /transl_table=11
                     /translation="MLVSLSLSSLLTLFFIMLMASGISGLLFLHPRVPLSFVRIHIGTL
                     ALPLLVSLLILANSGVSGNVGPWHLDSLACLMTFFVLAIGFIIQRFSVRYLMGDRSYRK
                     YFTLFTFTTGAASMTWLSGDLRLMVLFWGATLVGLTLLIRLNSAWQVASEAAKISGRLF
                     LLSWFSLFFAMMWLFHATGQWQLSLVVTNESLAGLGEWERTGIQLLIVLAVIIPAAQWP
                     FQRWLVESIVAPTPVSAIMHAGLVNAGGIILTRFSPLFHGGIASIILLLLAGISVLIGT
                     GISLVQVDYKRQLVGSTIGQMGFMLIQCALGAYIAAIIHLILHGLFKATLFLQAGSAVG
                     RHEVSARTNERTSYLWVMAGRILSLVIGVAFWLTAPGDGYHLISALILGWSLSVSWTQL
                     VAFGEGRIGRIAGLTVLGGAALVYFIIHHLFYKWLHTTIFQSVQPPMSAVMIVVCLLLF
                     GSALGTWVARHRSSVFFAVLYLWLVRLGEAKPKSVESHPDYLKQYIS"
     CDS             1961..4576
                     /locus_tag="ctg22_27"
                     /transl_table=11
                     /translation="MGITSVLTKDNVKKIDTDIDVQERDLNVFITSASRVIAPLWPIST
                     FAARNPWMGLENQPFDQVASWLKNTRDVDIYPSASMIRSAKNKGEIDEDFVEMGLQRWL
                     DSHSYHIPRDVAERFCHAALKLDPLPSDLLSSHKLEKLVSECDGLDHIENVFMQPLSSY
                     IENQDGERLVNILDHHVIKWSKLYLDDSQAGWTMPNREEGFYRAWQHLIQYDPALSKKQ
                     RERVKGWPKEAHLALQKALFALEIPESEIQTYLEGHLLSLPGWAGMMLWRSQQSSHEHA
                     LLTEYLAVRISMEWALIKPYLPLTNERSKKTISIAPLIAAWIHWGGLTLEEWSQMTASE
                     QNEYLSFAYSFDEKLRKKLWLEAWEQTYTDRLSQKIISKQRETGREKSALAQLAFCIDV
                     RSEPFRRQLEKEGPFETIGIAGFFGVPIATCELGSKHSHASLPIIQKPQNKIKEFADED
                     VFKKYNQRKQAIHSLSHTFKTMKQNALSSLLLPELSGPWLTLQMAARSFVPRKAGRFIR
                     NLREAWLRKPDTKLSLHHDATEAEIPVGFTDEEKVNYARQALKMMGLTENIAPLVVICG
                     HGSQSTNNPYSAALDCGACGGAAGGFNARVLAALCNLSEVREALLAEGIQIPEDTVFAA
                     AEHNTTVDELHWLYVPELSEAAQEAFEQIEAVMPKVRHHVNAERLDQLPNFQSKLKNPK
                     AEANRFAEDWSEIRPEWGLARNAAFIIGKRELTQDCDLEGRAFLHNYDWKQDESGELLA
                     NIIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLAGLPWQS
                     VMESDHEAYHSPLRLLILIQAPREYVERLLNNDSAFLQKVQNGWVRLASLDPEGCWESW
                     "
     CDS             4653..5180
                     /locus_tag="ctg22_28"
                     /transl_table=11
                     /translation="MNVNQNKKVLFLTDIENGLEPILQEATNTSAENMLTIQSYGAGIS
                     HPYGEIMRSVIFAIYQEDVEEIFVVGTKDKKTSAGNELTQLETMKDKIQTLDYLFQNCK
                     PEFFGGTVDEWLNENSSDTIEKSVDMIRHHPLVPSYVKVRGLFVHHKDGKPSIVEDPAI
                     KTGQALPDHCLS"
     CDS             5244..5534
                     /locus_tag="ctg22_29"
                     /transl_table=11
                     /translation="MSANLTDFVTKTIEDMNSFDRENMECMKKLIRKAIDFYHLKSYEE
                     VEETHSGNVRFLHVHSMMEENMLSKMIVVTRNGKTDLDIEGVYEGYVVREY"
     CDS             5592..5954
                     /locus_tag="ctg22_30"
                     /transl_table=11
                     /translation="MKKSKGSIESEISKSITQWEKDYLGRGSVSVKTDILRDMIIVNLK
                     GILTPAEYVVCGSKEGMLSIKQTRSELVESGIEGLKDIILKITGEKVKSFHTDLSSRTG
                     ERVMVFKLCNDLEKNL"
     CDS             6399..6701
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 69; E-value: 4.3e-21)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg22_31"
                     /transl_table=11
                     /translation="MEPIEVFKALSNESRLQILQWLKEPDRHFAPHEGIDMNTIGVCVS
                     QITDKLKMTQSTASQYLTILLRAGLIKAERIGKYTYYKRDEEAIEKLADFLKTEI"
     CDS             6828..8000
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 335.6; E-value: 4.8e-102)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_32"
                     /transl_table=11
                     /translation="MSNTWKIYILAIVSFLVGTSEYIISGILDQIAHTLGITLAAAGQL
                     ITIFSLVYALSTPVLMALTASMDRRKLMMYALGLFVFGNVLAFVLPGYGWFIAARIIMA
                     MGAGVVVVTALTIAAKIASEGKQGSAIATVVMGFTASLIIGVPLGRMIAVALGWKSVFG
                     AIALLGLIAMVVIFFTLPHTEGDKPVPLLQQLALFKKRKVAMGLSITFFWLGGYSVAYT
                     YLSPYLLNISGINGKLLSGVLLIFGIASLVGSKFGGYSTDKWGVPFTLVGGMTLHIVTL
                     ILLSLVTHSYIGVLVILILWSFAAWSTGPTQQFHLATIEPEMSGVLLSMNQSMMQFAMA
                     VGAGIGGVFVENVSLASITWVGALGVMIAIIASLMIFHSQPKQALKDINQ"
     CDS             8768..8938
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Antimicr18"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_33"
                     /sec_met_domain="Antimicr18 (E-value: 8e-07, bitscore:
                     23.8, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNNIFDLDINKKMESTSEVSAQTWATIGKTIVQSVKKCRTFTC
                     GCSLGSCSNCN"
     CDS_motif       8768..8839
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MEKNNIFDLDINKKMESTSEVSAQ"
                     /locus_tag="ctg22_33_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8840..8938
                     /prepeptide="core"
                     /locus_tag="ctg22_33_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="14.10"
                     /molecular_weight="3235.8"
                     /monoisotopic_mass="3233.6"
                     /core_sequence="TWATIGKTIVQSVKKCRTFTCGCSLGSCSNCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEKNNIFDLDINKKMESTSEVSAQ"
                     /leader_location="[8767:8839](+)"
                     /alternative_weights="3253.8"
                     /alternative_weights="3271.8"
                     /alternative_weights="3289.8"
                     /alternative_weights="3307.8"
     CDS             9026..10000
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 154.5; E-value: 9.1e-47)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_34"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.8e-26, bitscore:
                     87.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMTTNALPNQFSWNSYKVTNGYRLYDLQVGSPLIKIAVIDSGYD
                     PNHSEITGNIDKKKSCSFVDYENFNEDLYGHGTAVISVIVGKNQVKGVAPGITIISYKV
                     LDRNGFGKIEWVIHAILKAIEDCVHIINLSHVFTMFGLGNKGAFNKLQQAIDKARKKGI
                     IIVGAAGNQGVLLDMKSTSLYPTIKGINYVTSTNKNNYTSSYANIGSIIRFAAPSGELD
                     ETNNVTDLIIVAHPTNFPKTKFEKAIGLPDFYTVTCGTSISAAMFSSLIALVLTEYLIC
                     KQIHLSEKEILNIIQKNSSRVKDQNSIFEINAYSVIKFIKGLL"
     CDS             10001..13111
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     768.1; E-value: 2e-232)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_35"
                     /sec_met_domain="Lant_dehydr_N (E-value: 9.7e-133,
                     bitscore: 438.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.6e-08,
                     bitscore: 29.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 6e-32, bitscore:
                     106.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKYLSSDLFMYRKPILDLSFYKECLAFDNEFNEEEYIAKISNL
                     LNTNPTIAEAIYFASEPLYNSFLNIEKLKKKKRKSVIDSMLKFLIRMSTRPTPFGLFSG
                     IGVETFSGQDEYLTKDSEVIKNTRLDMCWIYFLIRKLESNLSILEQLTVENNSLVYNHG
                     DRIKLSYQSLLHSDDNDQSLEMLTLRKTAVMDYVYSQAEFGINYSTLRDSINKTYSVTD
                     DISNDFLNSLLKNEVIITNLRTSLVNSDPFENILNIISKMHNVEEELNYLVRLKKSIEE
                     YKKSSGELGISILKKIKKEMRVIGYEGDDFLRTDLYYVRNKKRYINNNQKDSIEKLAEI
                     LSLLGSVNSFQPLEAYRDEFIDKYGIFQEVPLLELIDEELGIGLPPEYHENRHKPSQPE
                     PSNEFHRIKNIISSWQAEVSLSKNHEIKLDDEKIKHLFNSEELNNIAVSQELELYFNIL
                     LDEHKENKLYLNPNCGSNSLFQTYGRFKYFLGESDKEYIKQFSHIEKDVIFAEVTYYPT
                     HGKTANIINAETCFDYEIAFSCNSSKDNKHSIALSDLYVGSTYNFIYLKSKKLDKIIIP
                     KLSHMFNYSMGPKVYRFLVDIGVQYQKQWSNIDSFFYDAPIKPRVIYNNIVLSPKKWNL
                     NKSIIPFECDSGEKFHYYIKDWKKRYKVPDFIYLIEFDNKLLLNLENISHIKIIYNEFK
                     KLSNNQSLHFLEAEKELFNNHNNEIEEYVFTLKSKLHQLELDSYMTNIQSEMPFKYIGD
                     NERLKFLGTEWIYVKLYGLGTRENEFIADELGSFIKKHLDKGTIKSSFFIRYSDPKQHL
                     RVRFKVEKNNIFDTVLPIIIKWLEEMRTKGFVNYYCFDPYNPEIERYGGEQSYKIAEDL
                     FFCDSLIVSEWIQINRSGNVNIDEVTFGVFNILQLLKLFNLNIEEQMTWLEINTKPQKY
                     ANKFRGKKSTLIELADLIYTNKKLDKYNKISSIIEIREKTAITYSKSIENNPDFLIKNI
                     IMSVIHMHCNRLYGINRDKENLVIGLAYHTIKNYNNALKYNNVLIPN"
     CDS             13136..14458
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     333.9; E-value: 2.2e-101)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_36"
                     /sec_met_domain="LANC_like (E-value: 2.5e-62, bitscore:
                     205.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKCKNQDFLTDILLDIANSIKDKSETEKIILGDQNNPEDIIEVV
                     SLAAGYPGICVFLGYMDKVFPEDGWDVVAHDYLTDLISLIQTNKTYSLSLFNGLAGVLV
                     ALETCSRGGTRYTTIINQVLTLILENYKHYLSEDLLKLKKEGVSASEYDVISGWTGVGR
                     TLLHFDQISNKGDISLKKALHDIAEYLLLVSSIDTLSNMPNWLISNENLPLDIEKKTYK
                     KGYFNSGMAHGISGVLAFLSILKKENYKIKNLELGIKNIQNWIFEKVKTHKGIYYIPNV
                     IENEVVRNEAFFNHRDAWCYGTPGVSRAIFLSGIALNDQRVKMKALELFKTFFLRDEKD
                     RKIISPTICHGYAGILMLTLRMYKDTNDRFLADKMHDILNEMLTFYSQLNFSKFNNYEL
                     ISGKIVEEKKVGLLEGSTGIALVLISFIFGQDSWDKIFLIS"
     CDS             14471..15061
                     /locus_tag="ctg22_37"
                     /transl_table=11
                     /translation="MIQAVLEITIKFLTELISFELPVYMYIWFAVLFIFSMIVENVQLA
                     IAKDSILNSILKRLGIKILSLLVVLIIGVLGSNFFAQVVEDAVNKESNLAYYILSTTIA
                     TALTIIEPIIETMKKFIKEQSNLAFANFTVSVICLTVTFQAVSSIFSDYFILATPYKVV
                     LIISSAIGIVYLVKFDQNNLEVNSESVHSNKND"
     CDS             15079..16836
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     251.8; E-value: 8.4e-77)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 316.8; E-value:
                     4.7e-96)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_38"
                     /transl_table=11
                     /translation="MGNNHLLLLLKLVKWPKKILVYILFSLLFTTILSLVIPILTKNTV
                     DQFTDGTVNWALTIMLAGLFLINILLSGLSFYYLAFLGENATYYIRDKMFSHILDLPLT
                     FFDKNESGQIVSRVIDDVELMNTFISDKIPNFASQLIVVAGSLILLFVLDWKITLLMLI
                     SVPISLAVMIPLGNKMYKISLEKQNNMAIFTARISSAFSGIRLTKSYTAEKEEYGKGNV
                     ILKRIFKLNLKDTKIQAYMMPIMSTVILMIILLLVGYGGIRLSEGTISPGTFVAIIFYL
                     VQFVTPLSSLSNFFTEYKKTLGATKRLYEIYSLKPEAENKQISSNAFNLGNGDLKFENI
                     SFQYNDPSSEVFNKLNLRFPKNKITAVVGPSGAGKSTLFNLIERLYEAQNGEIYYESTP
                     IKDIDLTVWRKKIGYVMQDTLMITGTIKENLTYGLSGSVSQETIIKYSKLANAHDFIME
                     LPDNYETFIGERGIKLSGGQKQRIAIARALIKNPEILLLDEATSNLDSESEILVQQSIN
                     RLVRDRTTIIIAHRLSTIRDADNIVFLENGVVTGSGNHLDLINNHEKYREFVNGQLLNN
                     TSISASSLS"
     CDS             17038..18015
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_39"
                     /sec_met_domain="PF00561 (E-value: 5.5e-08, bitscore: 27.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLWKVLKIVFVSLAALVLLVSVSVFIYHHFQLNKEAALLKGKG
                     TVVDVDGKKMNVYQEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVDRAGYG
                     YSEVSHDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAMYWAQKYPKEIKAIIA
                     MDIGLPQQYVTYKLSGVDRLKVRGFHLLTSIGFHRFMPSAVYNPEVIRQSFLTDEEKEI
                     YKAINFKQFFNADMEHELLQSYQNGSKSVNLPAPKETPVLILDAVSDQNRHSKYAIQNR
                     KDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKLSMEFMRKVR"
     CDS             18017..18688
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 127.8; E-value: 7.7e-39)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg22_40"
                     /transl_table=11
                     /translation="MKGYHILIVEDDVMIGELLQKILQREGYRVIWKTDGADVLSVIQK
                     VDLVIMDVMLPGEDGYQMSAKIKELGLGIPVIFLSARNDMDSKLQGLQIGEDYMVKPFD
                     PRELLLRMRNMLEHHYGTFTQIKHLYIDAVTKKVFNESLHDEVLFTAIERKIFFYLYEN
                     RDSILTKEHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEMIENIYGEGYRLNTVVK
                     K"
     CDS             18685..19671
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 59.4; E-value: 5.8e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg22_41"
                     /transl_table=11
                     /translation="MKLKTKYQLLLFTAVISVPMLLLAVSVLMSVIYDSMFKPMNHGMP
                     FHRSFAYPAMIVVFLISLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQRVPDKIEVK
                     RADEIGELIKSVNLLIERTTYRELELRQQEEIKKELLQKLRHDINTPLTALRLQLFYLE
                     DQCHGQAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMSGIELHYKAADQDVIWMSNALWMQRLFDNIFQNTLKHSKAEKMEVTIEHDNVFIR
                     DDGIGFDRNESSEGLGLKIIEDTCRLLAITYELHTNDSGTGFLFSKE"
     CDS             19730..19981
                     /locus_tag="ctg22_42"
                     /transl_table=11
                     /translation="MNSICLKKSSKRLSTSQAVLVTDIADTGITAAAGADIIAATAARA
                     KEDTTTVMAAVIVTNAGATAAVNPKKFLFRFWDKGFFM"
     CDS             complement(19974..20744)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 111.8;
                     E-value: 6.8e-34)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg22_43"
                     /sec_met_domain="Pkinase (E-value: 4.4e-33, bitscore:
                     109.4, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKLLKKLLFDRPLKNGVILNHQYKIEECLGMGGYGLVYLCTDI
                     LTQTPYVLKQLRPTKAKKEKEKVRFQQEIKLLNSIHHPQIPGFIDEFIIDGQAYYVMQF
                     IEGENIEELLFFRKQPFTELMALQLISQLLEIIEYLHDRLIFHSDIRTPNIIINDGRLC
                     LIDFGLAKQLTPEEMEEIKVRKQDDFFDLGETLLFLLYSQYKGKKKKNGTWLEELTLTK
                     EVTLLLKRLLGIEEEYQHTASIREDLNRAIQSVT"
     CDS             complement(20830..21687)
                     /locus_tag="ctg22_44"
                     /transl_table=11
                     /translation="MVKKWLIPFAVMLSVLFTFTYSASAAGVTAITGNNSFDTAMPIGY
                     WKYKNIDTTILEAGQDEAYFTFTANKGEKVYVRSTYQSAYTGMKIEIYDKNRIPVSQGT
                     EVINPNTFSSFIYANADAQNTTDTFYVKVSRGTYTGNMYFTLSIEDRIKSGSGTFQFSG
                     VAENKGNTSLSPSGSDSSVIKVDLTNQSGIPRDAIVTRVQTTATQTPSQGNTRHLIMTS
                     ENNEWRRALVNSSTSGSYDISLSDQLSVAKVWSFKYNTLATARSTMSNVKAKIDYEYDV
                     TKQF"
     CDS             21819..23003
                     /locus_tag="ctg22_45"
                     /transl_table=11
                     /translation="MRLNRQFIRTQLMAQNILSKNAPAKRENATENPAAVLEKAYSRLK
                     SQSSTGGINQFNYSKTSVSGNSGAFSKVYQSANFRTVTDTGEETVIQSQNPYECESDIR
                     IKILDEKYSRMNAINKTKSDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEWLFK
                     GKAQNYNLQDAVFRNVTFHGEVEAENEKVYQRGQVNQQLQVLLNRNHIHIPEGTELTFT
                     ITPIDYQVRVSGTDDQDLIKQIEQVLQSGDNSKELFLHIMKSQSSDSAQFSEEAYQKYQ
                     AAREMYEVTGYHLKDLEVIDGRYVTPEGRDLMDVYKEELEKDPVQKQTASYAISYYRSE
                     LSKIAEAGYNAIPDFILSIDYSNGSLIDVGQSKSYGTGDTGWLEALKRQTGVNY"
ORIGIN
        1 tcttatacgt aacttaataa tcgatgcaga tgtttatttt tccttttaaa atatgtaggc
       61 ctttagcatt cttttcatat ttaattttaa atattgatag gatgaaaaag tatcctaata
      121 aaaaaggaag agaacatgag tcgatttatt tgataatcag gactatatta aaggaaatga
      181 aaacatagca taaagtaaag accaataata aggtagcact tcaaaaaact tcgctgaagt
      241 tagttgaagt gaagccgaca attttcagga ttcaatgatc taacataatc attgaaattt
      301 tgaagttgtc ggcttttttg ttggaaaaaa atagagataa ataaaaattg aaataaataa
      361 tagacaaata tgatctgatt gaaaggtctt ttgaccaata atgagtttta aaaaagggag
      421 aatttagaat gttagtttcg ctgagtttgt catcattatt aacattattt tttattatgc
      481 ttatggcttc tgggattagt ggactattgt ttttacatcc gcgtgtaccc ttgagttttg
      541 tccgcattca tattgggacc ttggctttac cacttttggt ttccttactg attcttgcca
      601 atagtggtgt gagcggaaat gttggccctt ggcacttaga ttccttagct tgtttaatga
      661 ctttctttgt tcttgcaatt ggattcatca ttcagcgttt ttctgtacgt tacttaatgg
      721 gggatcgatc ttatcgaaaa tattttacgc tttttacttt cacaacaggg gctgcttcaa
      781 tgacatggtt aagtggtgat ctccgcttga tggttctatt ttggggagca actcttgttg
      841 gtttaacctt acttataagg ttaaacagtg cttggcaagt ggctagtgaa gcagccaaaa
      901 tttctggccg gttatttttg ttaagttggt tttctttgtt ttttgcgatg atgtggcttt
      961 ttcatgccac aggtcaatgg cagttatcat tggttgtaac aaatgaaagt ttagctgggc
     1021 tgggagaatg ggagagaaca gggattcagc tattgattgt actggcggtg atcattcctg
     1081 cagctcaatg gccgttccaa agatggttgg ttgagtctat tgttgctcca accccagttt
     1141 ctgcaattat gcatgcaggt ttagtaaatg ctggaggaat aatactaact cgattttcac
     1201 ctctatttca tggtggtatc gcttcgatta tcttacttct gcttgctggc atttctgtat
     1261 tgattggaac tggaattagt ttagtccagg ttgattataa acgccagtta gtaggctcca
     1321 cgattggaca aatggggttt atgctcattc agtgtgcatt aggcgcctat atagcagcca
     1381 ttattcatct tattttacat ggtttattca aagctacgtt gtttctacaa gctggttcag
     1441 cagtagggcg tcatgaagta tcggctcgca ctaatgaaag aacatcctat ttatgggtca
     1501 tggctggtcg gattttatcc ttagtaatag gtgttgcttt ttggctcact gctcctggag
     1561 acgggtatca cttaataagt gcgctgatct tagggtggtc attgtccgtt tcttggactc
     1621 agcttgtcgc ttttggagag ggccgaattg gccggattgc cggcttaact gttttaggag
     1681 gagcagccct cgtatatttt atcattcatc accttttcta taagtggctg catacaacca
     1741 tttttcaaag tgttcaacct ccaatgtcag ctgtcatgat tgtcgtatgt ctcttactct
     1801 ttggcagtgc tttaggtacg tgggttgctc gtcatcgttc ttccgttttt tttgcggtac
     1861 tctatctttg gttagtccga ttaggtgaag caaaaccaaa gtcagtagag agtcacccag
     1921 actaccttaa acaatatatt tcataaggag ctaatctgag atgggcatta catccgtatt
     1981 aacgaaagat aatgtaaaaa agatagatac agatattgat gttcaagaaa gggatcttaa
     2041 cgttttcatt acatctgcca gccgagtgat tgcgccactt tggcctattt ctacatttgc
     2101 tgcacgtaat ccgtggatgg gacttgaaaa ccaacctttt gatcaggttg caagttggtt
     2161 gaaaaacact cgcgatgttg atatataccc tagtgcgtct atgatccgtt cagcaaagaa
     2221 taaaggtgag attgatgaag attttgtgga aatggggctg cagcgttggc ttgattcaca
     2281 ttcctatcac atcccacggg acgtggcaga gcgattttgt catgctgcat taaagttaga
     2341 tcccctgcct tccgaccttt tatcatcaca taagctggag aaattagtaa gtgaatgtga
     2401 tggattggat catatcgaga atgtgtttat gcagccacta agttcgtata tagagaatca
     2461 agacggtgaa aggctagtca atatactaga tcatcatgtc attaagtgga gtaaattata
     2521 tcttgatgac tctcaagcag gctggacaat gcctaatcgt gaggaaggtt tctatcgtgc
     2581 ttggcagcat ctcattcaat atgatccagc acttagcaaa aagcagcgag aaagggtaaa
     2641 gggttggccg aaagaggcac atttggcttt acagaaagct ttattcgcac tagaaatccc
     2701 agagtcagaa atccagactt atcttgaagg tcatttactt tcattacctg gatgggcagg
     2761 gatgatgctt tggcgctccc agcaatcgag ccacgaacat gcactcctaa cagaatattt
     2821 agcggttcga atatccatgg agtgggctct tataaagcca tacttacctt tgactaatga
     2881 acgatctaag aaaacaattt caattgctcc ccttatagca gcttggattc attggggtgg
     2941 gcttacatta gaagaatggt cacagatgac ggccagtgaa caaaacgaat atttatcatt
     3001 tgcctacagc tttgatgaga aacttcgcaa gaaactttgg ttagaagctt gggaacaaac
     3061 gtacactgat cgattaagcc agaagatcat ctcgaaacaa cgtgaaaccg gccgtgaaaa
     3121 atctgcatta gctcaattag cattctgcat cgatgtacga tcagaacctt ttcgtcgtca
     3181 actagaaaaa gaaggcccgt ttgaaacgat tggtattgct ggtttcttcg gggtgccgat
     3241 tgcaacttgt gaacttggca gtaaacacag tcatgcttcc ttgccgatca tacaaaaacc
     3301 gcaaaataaa ataaaagagt tcgcagatga ggatgtattc aaaaaataca atcaacggaa
     3361 gcaagcaatt cattctttaa gccatacctt taaaacgatg aagcagaatg cgctttcgag
     3421 cttactactg cctgagctaa gcggaccttg gcttactctg caaatggcag cccgtagctt
     3481 tgtgccaaga aaggcgggtc gtttcattcg taatctccgt gaggcttggt tacgcaaacc
     3541 tgatacaaaa ctctcgcttc atcatgatgc tacagaggca gaaatacctg tgggttttac
     3601 tgatgaagaa aaagtgaact atgctcgcca agcattaaaa atgatggggt taacagaaaa
     3661 catcgcacca ttggtcgtga tctgcgggca tggcagtcaa agcactaata atccttattc
     3721 cgcagccctt gattgtggtg cctgcggtgg agcggccggt ggattcaatg ctagagtttt
     3781 agctgcttta tgtaatctat cagaggtacg agaagctctt ttagctgaag gaattcaaat
     3841 tcctgaggat acggtttttg cagcagccga acataataca acagtagatg aattacattg
     3901 gctttatgta ccagagcttt ccgaagctgc acaagaagca tttgaacaaa ttgaagctgt
     3961 tatgccgaaa gtgagacatc atgtaaacgc agaacgtctg gaccaattac cgaatttcca
     4021 atcgaagcta aaaaatccga aggctgaggc aaaccgattt gcggaagatt ggagtgagat
     4081 acgtccggaa tggggactgg ctcgtaatgc cgcctttatt atcggtaaac gtgaactaac
     4141 tcaggattgt gatttggaag gcagagcctt tctccataat tatgattgga agcaggatga
     4201 aagcggtgaa ctcctagcaa atattattgc aggacctgga actgtggccc aatggattaa
     4261 tttacaatat tacgcatcaa cggtagcacc tcattattat ggcagcggaa ataaagcaac
     4321 tcaaaccgtt actgcaggtc tcggcgttat gcaggggaat gcaagcgatt tgttagccgg
     4381 actgccttgg caatccgtca tggaatcaga tcacgaggcc tatcattctc ctcttcgttt
     4441 attgatactc atccaagcac ctagagaata tgtagaacgg ttattaaata atgattcagc
     4501 atttctgcaa aaagttcaaa atggatgggt ccgactggct agtcttgatc cagaaggatg
     4561 ttgggaaagc tggtaatgat gaatctaagc atttatcaaa tggatttgtt actcaataca
     4621 aaaatgataa acataaggaa gaggtgtgct gtatgaatgt aaaccaaaat aaaaaagtat
     4681 tatttttgac ggatattgaa aacggtttgg agcctatttt acaagaagcg actaacactt
     4741 ctgcagagaa tatgttgact atacaaagct atggtgccgg tatttcacat ccttatggag
     4801 aaatcatgag gtctgttatt tttgcgattt accaggaaga tgttgaggag atttttgtag
     4861 tgggaacaaa agataagaag acttccgcag gtaatgaact aactcaactt gaaacaatga
     4921 aagataaaat acaaacattg gattatctct ttcaaaattg caagcctgaa ttttttggtg
     4981 gtacggtcga tgaatggcta aatgaaaata gcagtgacac cattgaaaaa agtgttgata
     5041 tgattcgaca tcatccccta gtgccgtcat atgttaaagt tagaggttta ttcgttcatc
     5101 ataaggatgg aaaaccctca attgtggagg atccagctat taaaacaggt caagccttac
     5161 ctgatcattg cttgtcatga tgaaatgcag gttcaacttc taaacgcacc catataggga
     5221 gaaagcagtt ctaaggagat tgtatgagcg ctaatttaac tgattttgtc acgaaaacaa
     5281 tagaggacat gaactcgttt gatcgtgaaa atatggaatg tatgaaaaaa ctaattagaa
     5341 aagcaattga tttttatcat ctaaagtctt atgaagaagt tgaggaaacc cattcaggaa
     5401 atgttcgatt tttgcatgtc cactctatga tggaagaaaa tatgttatcc aaaatgatag
     5461 tggtcacaag aaacggtaaa actgatttgg atattgaagg tgtatatgaa ggatatgttg
     5521 taagagaata ttaatgagac gaaatcacaa atagaatatg ccaatttttt tgctcaggag
     5581 atgtattaga tatgaaaaag tctaagggtt ctattgaatc agagatcagt aagtccatca
     5641 ctcaatggga gaaggattat cttggacggg ggtctgtatc tgttaagact gatatactgc
     5701 gggacatgat catcgtcaat ttaaaaggga ttttaacacc agccgaatat gtagtttgtg
     5761 gatcaaaaga gggtatgtta tctatcaaac aaactcgttc ggagttagtc gaatcaggta
     5821 tagaaggcct taaggatatt atcttaaaaa taaccggaga aaaagtgaaa agttttcata
     5881 ctgatttaag ctcccggaca ggtgaacgag tgatggtgtt taaattatgt aatgatctag
     5941 agaaaaatct ttaatgtaaa tgttttatga tcactgatat tcaagccagc agagggctga
     6001 aggcattctg gttattcata agttgtaata ttttttattc ataacctaag cggacataaa
     6061 gagatgtcaa ttcatagtac actgacttgt tattcctgtc gaaagatcta acatccgcag
     6121 ttgttatgag cggatgtttt ttacatctaa atttgctgct ggtgattagt cacttgaaca
     6181 attgaaaaca tccttgtcac ctgctgggtt cccccaagtg ttttgtgaaa tgattatgag
     6241 accaatttcg taaagcttgc tgataaattt aagcggtgaa caaaattgat atgctgtctt
     6301 cagtttcatt tcacggaatt agtcagagat aaacctttaa ttaaatatat ccaaaaaaac
     6361 ggattgacat atcgaaatat aacgatataa taatcgatat ggaaccaatt gaagtattca
     6421 aagccttatc aaatgaatca aggctgcaaa ttttacaatg gctgaaggag cccgatcgtc
     6481 attttgcacc ccatgaaggg attgatatga acacaatcgg ggtatgtgtc agtcaaataa
     6541 cagacaaatt gaaaatgacg caatcgacag cttctcaata tcttaccatc cttttaagag
     6601 ccggcttgat taaggcggag cgtatcggaa agtacacgta ttacaaaaga gatgaagaag
     6661 ccattgagaa acttgctgac tttcttaaaa cagagatata aaaataaaca tcaaaagatg
     6721 tttattttta caccatacat atcgacatat tacgatgtgt ttatttttta taacaacata
     6781 tcgataattc gtgatatgtt tattaataat taaggagtga atgttttatg tctaacactt
     6841 ggaaaattta tattttagcc attgtcagct ttttagttgg aacctcagag tacatcattt
     6901 ccggaatttt ggatcaaatt gctcatactc tcgggattac tttagctgcc gcgggccagc
     6961 ttattaccat tttctcactt gtatatgctc tttctacacc cgtacttatg gcgttgacag
     7021 caagtatgga tagacgcaaa ttgatgatgt atgccctagg tttgtttgtg ttcggtaatg
     7081 tcctggcttt tgtactgcct ggttatggat ggtttattgc agcgcggatc attatggcga
     7141 tgggagcagg tgtggtggtt gtcaccgcat taacgattgc cgctaagatt gcatcggaag
     7201 ggaagcaggg aagtgccatc gctacggtcg tgatgggatt taccgcttct ttaatcattg
     7261 gtgttccgct tggaagaatg atagcagtag cattaggctg gaagtctgta tttggagcaa
     7321 ttgctttgtt gggattgatc gcaatggtcg ttattttctt tactcttccg catactgaag
     7381 gggataagcc tgtgcctttg cttcaacagc ttgctctttt caaaaaacgg aaagtggcta
     7441 tgggattatc aatcactttc ttctggctcg ggggatattc tgttgcttac acttatttgt
     7501 caccgtatct cttgaacatc tcaggtataa acggcaagtt gcttagcggt gttttgctta
     7561 tatttggaat tgccagtttg gttggatcaa agtttggggg atatagcacc gataaatggg
     7621 gagtaccctt tacactcgtt ggtgggatga cattgcatat cgtcacactg attctgctgt
     7681 cacttgttac tcattcctat atcggagtgt tggtgattct catattatgg tcgtttgccg
     7741 catggtctac aggtccgaca cagcaatttc acctggctac aatagaaccg gaaatgtcag
     7801 gtgttttgct tagcatgaat cagtcaatga tgcaattcgc catggcggtc ggcgcaggta
     7861 taggaggagt ttttgtggaa aacgtatcat tggcctcgat tacctgggtt ggtgcgttag
     7921 gggttatgat tgccattatt gcatcattaa tgatttttca ttcacaaccg aaacaggcgc
     7981 taaaagatat caatcaataa tttcgaaaga tctaacatcc gctcgttata caagcgggtg
     8041 tttttttata agcattcaaa gtcagtccat gcatgagcct tccaagggcc gacatcgttc
     8101 tgtatgtgtc gaaggcgcac tgaagctgaa tgagatttct taaggctttg ccgcggcgag
     8161 ctgaagtaca gtacgattgc cttgatcgaa cactggaaac acaagagaac gtaaacctga
     8221 acatccgcgt aaacgtcaag gaagttgcca cttggggagt aaacacttgc atcatctcgc
     8281 tgaaaggcct agacaatgcg gatgacagat tcgtattgcc ggaagtaaac acagcgcttg
     8341 ctctgtttcc gttgtcgatt gcagctgatt gcttactaat gctgccctgc atctcggttg
     8401 tgatgtcgat aagcagcgta accttgtgaa gagtgttact gtggagtaag atttttaacc
     8461 cctttggaat atagatcaaa aggtttttta atacttataa actgaaggag atcaatttta
     8521 aatcgtttta aaactattaa aggaagttta gtaacgataa cttaaacatc tggctaataa
     8581 gattactgag gatacatcaa aagtcgaata gtaatagtag agagtaaaag taaccgtaag
     8641 aagaattata acaattagtt agcaaataat taaaaaatgt cccaaaaaaa gtattgacta
     8701 actttttttg ggatagtact attgaattgc aaccggttga aagtatcaaa aaaaggagga
     8761 aatggaaatg gagaagaata atatttttga cctagacatt aataaaaaga tggaatctac
     8821 tagtgaggtt tctgctcaaa cttgggctac aatcggaaaa actattgtgc agtctgtgaa
     8881 aaaatgtaga acatttactt gtggatgttc gctaggctct tgcagtaact gtaactaatt
     8941 aggggatgag cagagggagt taaaatacat actatattaa aactccctct tcttctaaag
     9001 acaaggagta aacaattcca taaatatgaa tatgactaca aatgctttac ctaaccaatt
     9061 ttcttggaac tcttataaag taacaaatgg atataggcta tatgatcttc aagttgggag
     9121 ccctttaatt aagatagctg taattgatag tgggtatgat cctaatcatt ccgagattac
     9181 tggaaatatt gataaaaaaa aatcttgttc attcgttgat tatgagaatt ttaatgaaga
     9241 tctatatggg cacggtacag ctgttattag tgtgattgta gggaaaaatc aagttaaagg
     9301 agtagctccc ggaattacaa ttattagtta taaagttcta gatagaaatg gttttgggaa
     9361 aatagaatgg gtaatacatg ctattttaaa agccattgaa gattgtgtcc acattataaa
     9421 tttaagtcat gtttttacta tgttcggatt gggaaataaa ggagcattca ataaacttca
     9481 gcaggccatt gataaagcca gaaagaaagg cataataatt gtaggggcag cagggaatca
     9541 aggagtttta ttagatatga agagcacaag tttataccct acaattaagg gaattaacta
     9601 tgtcacctca acaaataaaa ataattacac ctcatcttac gcaaatattg ggtcaattat
     9661 tcgatttgct gcaccatcag gggaacttga tgaaacaaat aatgttacag acttaataat
     9721 agttgcacat cccacaaatt ttccaaaaac aaagtttgaa aaagcaattg ggcttccgga
     9781 cttttataca gttacatgtg gaactagtat atcagcagct atgttttcga gtctaatagc
     9841 attagtattg actgaatatt tgatatgtaa gcaaattcac ctatcagaaa aagaaattct
     9901 taatataatc caaaaaaact cctcacgagt aaaagatcaa aattctattt tcgaaataaa
     9961 tgcttatagt gtaataaaat ttatcaaagg attgttataa atgaatacaa aatatttaag
    10021 ctcagacttg tttatgtata gaaagccgat attggactta tcgttttata aagagtgttt
    10081 agcttttgat aatgaattta acgaagagga atacatagcg aagataagta acttattaaa
    10141 cactaatccc actatagcag aggccattta ttttgcaagt gaaccactat ataattcttt
    10201 tttaaatata gaaaaattaa aaaagaaaaa gcgcaagagt gttattgata gtatgctaaa
    10261 gtttttaata agaatgagta caagaccaac tccatttggc cttttttcag gtattggggt
    10321 tgaaacattt tcaggtcagg atgaatattt aactaaagat tctgaagtta taaaaaatac
    10381 tcgtttggat atgtgttgga tctatttctt aataagaaaa ttagagagta accttagtat
    10441 tctcgagcag ttaactgtgg aaaataactc actggtttat aatcacggtg atagaatcaa
    10501 attaagttat caaagtctat tacacagtga cgataatgat cagtcattag aaatgttaac
    10561 ccttagaaag acagcagtaa tggattatgt ctattcgcaa gcagaattcg gtatcaatta
    10621 ctctacgtta agagatagta taaataaaac atatagtgtt actgatgaca tatcaaatga
    10681 ttttttaaat agtctattaa aaaatgaagt tattataact aacttaagaa catctcttgt
    10741 taattctgat ccttttgaaa atatattaaa cataattagt aaaatgcata atgtagagga
    10801 agaattgaat tatttagttc gattaaaaaa atcgattgaa gaatacaaaa aatcttctgg
    10861 ggaattaggt ataagtattt taaagaaaat caaaaaggaa atgcgagtaa taggatacga
    10921 aggggatgat ttccttagaa cagatttgta ttatgtgaga aataaaaaac gatatattaa
    10981 taataaccaa aaagatagta tagagaagct agctgagatt ctttctctat taggatcagt
    11041 aaactctttc caacctttag aagcctatag agatgagttc attgataaat atggtatttt
    11101 tcaagaggta cctctcctcg aactcataga tgaagaatta ggtattggtt taccacctga
    11161 atatcatgaa aacaggcata aaccatcaca accagaaccg agtaatgaat ttcataggat
    11221 aaaaaatatt atatcttctt ggcaagcgga ggtgagttta tccaaaaatc atgagattaa
    11281 attagatgat gaaaagatta aacatttatt taactcggaa gaattaaata acattgcggt
    11341 atcacaagaa ttagaacttt attttaatat tttacttgat gaacacaaag aaaataaact
    11401 ctatttaaat cctaactgtg gttctaattc tctttttcaa acatatggaa gattcaaata
    11461 ttttttgggt gaaagtgata aagagtacat aaaacaattc tcacatatag aaaaagatgt
    11521 tatttttgca gaggttacgt attatcctac ccatggaaaa actgctaaca ttataaatgc
    11581 tgaaacatgc tttgattatg agatagcttt tagctgtaat tcgtccaaag ataataagca
    11641 ctcaattgcg ttgtctgact tatacgttgg gtcaacatat aactttattt atcttaagtc
    11701 aaaaaagttg gataaaatca taataccaaa attaagtcat atgtttaatt attcaatggg
    11761 ccctaaagtt tatagatttc ttgttgatat tggtgttcag tatcaaaaac aatggtctaa
    11821 tatagatagt ttcttttatg atgctccaat taaaccgagg gttatatata ataatattgt
    11881 attatcacct aaaaagtgga acttgaataa aagtattatt ccatttgaat gtgactctgg
    11941 agaaaaattc cattactata taaaagattg gaagaagaga tataaggtac ctgattttat
    12001 atatttaata gaatttgata ataaacttct gctgaactta gaaaatatct cacacattaa
    12061 aattatctat aatgaattta agaagctttc gaataatcaa tcactacatt ttttagaagc
    12121 agagaaagag ttgtttaata atcataacaa tgaaatagaa gaatacgttt ttactttaaa
    12181 gtcaaagtta catcaattag aacttgattc ttatatgaca aatattcaga gtgaaatgcc
    12241 ttttaaatat attggtgaca atgaaaggct taaattctta ggtacagaat ggatttatgt
    12301 gaaattatat ggattaggca ctagagaaaa tgaatttata gctgatgaac ttggctcgtt
    12361 tataaaaaaa catttagata aaggtactat taagtctagc tttttcatta gatatagtga
    12421 ccctaagcag catttacgtg ttagatttaa agttgaaaag aataacattt tcgatactgt
    12481 actcccgatt ataataaaat ggttagaaga aatgagaaca aagggttttg ttaattatta
    12541 ttgtttcgat ccatacaacc ctgaaataga aagatacgga ggggaacaat catataagat
    12601 tgcagaagat ttattttttt gtgactcatt gattgtttct gagtggatac aaattaacag
    12661 atctggaaat gttaatattg atgaagtgac ctttggagtt tttaatattc ttcaactatt
    12721 aaaattattt aatttaaata ttgaagagca aatgacatgg ttagaaatta atacaaaacc
    12781 gcagaaatac gctaataaat tcagagggaa aaaaagtact ttaattgagc tggcagactt
    12841 aatctatact aataagaaac ttgataaata taataaaatc tcaagtatta tagagatacg
    12901 agaaaaaact gcaatcacct attctaagag catagaaaat aatccagatt tcttaataaa
    12961 aaatattata atgagtgtaa tacacatgca ttgtaacaga ttatatggaa taaacaggga
    13021 caaagaaaac ttagttattg ggttagcata tcataccatt aaaaattata ataatgctct
    13081 aaagtataat aatgttttaa tccctaacta aattttaatt gaaaggaaag aattaatgca
    13141 gaaatgcaag aatcaagatt ttttaaccga tatcctttta gatatagcta attcaattaa
    13201 agataagtca gaaaccgaaa aaataatact tggtgatcaa aataatcctg aagatataat
    13261 tgaagtagta tcattggcag caggatatcc aggaatttgt gtgtttttag gttatatgga
    13321 taaagttttc cctgaagatg gatgggatgt tgtggcacac gactatttaa cagatttaat
    13381 ttccttaatt cagactaata aaacatactc actatcccta tttaatgggt tggcaggtgt
    13441 tttagtggct cttgaaactt gctctagagg cggaacaaga tatactacaa taataaatca
    13501 agtgctaacc ctaattttag aaaactataa acattatttg tctgaggact tgttgaagct
    13561 aaagaaagag ggagtgtccg cttctgaata tgatgttata agtggttgga caggtgttgg
    13621 aagaacccta ttgcattttg atcaaatatc aaataaagga gatatttcat taaaaaaagc
    13681 attgcatgat atagcagaat atttactgtt agttagcagt attgatactc taagtaatat
    13741 gccaaattgg cttatatcca atgaaaacct tcctttagat atcgagaaaa aaacttataa
    13801 aaaaggatat tttaattctg gcatggcgca tggaatttct ggagttttag catttttatc
    13861 gattctgaaa aaagaaaact ataaaataaa gaatttagaa ttaggtatta aaaacattca
    13921 aaattggata ttcgaaaagg taaaaacaca caaaggaatt tattatatac ctaatgtaat
    13981 tgaaaatgaa gttgttagaa atgaggcttt ttttaaccac agagatgcct ggtgctatgg
    14041 tacaccaggt gtgtcaagag caatcttttt atcaggtata gctttgaacg atcaaagagt
    14101 taaaatgaaa gccctagaac tgtttaagac atttttttta cgtgatgaga aagatagaaa
    14161 aattatatcc cccacaattt gtcatggata tgccggcata ttaatgttga ctctaagaat
    14221 gtataaagat actaatgacc gatttctagc tgataaaatg catgatatac ttaatgaaat
    14281 gttaactttt tactctcaat taaacttttc caaattcaat aattatgaat taataagtgg
    14341 gaaaattgta gaagagaaaa aagtgggttt gttagaagga agtacgggaa ttgccttagt
    14401 tttaatttct ttcatttttg gtcaagattc gtgggacaag atatttctga taagttaaag
    14461 ggggataaaa ttgatacaag cagtactaga aatcactatt aaatttctaa cggaattaat
    14521 ctcttttgaa ttgccagtat atatgtatat ttggttcgca gttcttttca tattttcaat
    14581 gatagtcgaa aatgtacaat tggcaatagc taaggatagt atattaaatt ctattttaaa
    14641 aagattagga ataaaaattt taagtctatt ggtggtctta attattgggg ttttaggatc
    14701 aaactttttt gctcaggttg ttgaagacgc agtcaataaa gaatctaact tagcttatta
    14761 tattctgtct actacaatag ctacagcatt gaccataatc gaaccaataa ttgagacgat
    14821 gaaaaagttt ataaaagaac aatcaaatct tgcttttgca aattttacag tcagtgttat
    14881 ttgtcttact gtaacgtttc aagcagtctc aagcatcttt agtgattatt ttattttggc
    14941 caccccttat aaagtggtgt taataatttc atcagcaatt ggtattgtat atttggtgaa
    15001 attcgatcaa aataatttag aagttaatag cgaaagtgtt cattcaaata aaaatgatta
    15061 atctaagagg ttatacatat gggcaataac catttactat tactgcttaa acttgttaaa
    15121 tggccaaaaa aaatattagt atatatttta ttttcattac tatttacaac tatactatcc
    15181 ttggtaatac caatattgac taaaaatact gttgatcaat tcactgatgg aacagtaaat
    15241 tgggccttaa caataatgtt agcaggttta tttctcataa atattttatt aagtggatta
    15301 tctttttatt atctagcatt tttaggtgag aatgcgactt actatatacg agataaaatg
    15361 ttttctcata ttttagattt acctctaacg ttttttgata aaaatgaatc tggtcaaatt
    15421 gtaagtagag ttatagatga tgttgagtta atgaatactt ttatttctga caagatacca
    15481 aactttgctt ctcaattgat agtagttgcc ggatcattaa ttcttctgtt tgtgctggat
    15541 tggaaaataa cattacttat gttgatttct gttcctattt cattagctgt tatgattcca
    15601 ttggggaata agatgtataa aatttcttta gaaaaacaaa ataatatggc aatatttact
    15661 gcaagaataa gtagtgcatt ttcaggaatt agacttacaa aaagttatac tgcagaaaaa
    15721 gaagagtatg ggaaaggtaa tgtcatttta aaaagaattt ttaagcttaa tctaaaagat
    15781 actaagatac aagcttatat gatgcctatt atgtctactg ttatactaat gataatatta
    15841 ttgttagtgg ggtatggggg gataaggtta tcggaaggaa ctatttcacc aggtaccttt
    15901 gttgcaataa ttttttactt agttcaattt gttacacctc tttcctctct gtctaacttt
    15961 tttactgaat ataaaaaaac actaggtgca acaaaaagat tatatgaaat atattcacta
    16021 aaacccgagg ccgaaaataa acaaattagc agtaatgcat ttaacttggg aaatggggat
    16081 ctgaaatttg agaacatttc gtttcagtat aacgatcctt cttctgaagt atttaacaaa
    16141 ctgaatttgc gttttccaaa aaataagata acagctgttg taggtccttc tggagctgga
    16201 aaatcaactt tatttaattt aatagaacgt ttgtatgaag ctcaaaatgg tgaaatctat
    16261 tatgaatcaa ctcctataaa agacattgat ttgactgttt ggagaaaaaa aattggttat
    16321 gtaatgcaag atactttgat gatcaccggc acgataaaag agaacctgac gtacggttta
    16381 tcaggctctg tatctcaaga aactataatt aaatattcta aattagccaa tgcccatgat
    16441 tttattatgg agcttccaga taattatgaa acctttattg gagaaagggg tataaaatta
    16501 tcaggtggtc aaaaacaaag aattgcaata gcaagagcat taattaaaaa ccctgaaata
    16561 cttttattag atgaggcaac ttctaattta gacagtgaaa gtgaaatatt ggtacaacaa
    16621 tctataaata gactagttcg agatagaacc actattatta tagctcatag attgtcaacg
    16681 attagagatg cagataacat tgtattttta gaaaatggag tggttacagg aagcggtaat
    16741 catttggacc taataaataa ccatgaaaaa taccgagagt ttgttaacgg tcaattgcta
    16801 aataacactt caataagcgc gagttctcta agttaattgt gcataaataa tgagaccact
    16861 tgggtacact ttttatcggt tctataacca taaaaagcag ctgaactttt agttcagctg
    16921 ctttttgatt gaatcttgcg actagaaagt caaatgtgaa aataaaactg ttccaaagtt
    16981 aatcagaaat ttattttcat attgtatcct ttcagtatca agtgaaagga gcatcatatg
    17041 aaaacattat ggaaagtcct aaaaattgtt tttgtcagct tggctgcttt ggttttgctt
    17101 gtatccgtct cggtatttat ttatcaccat ttccagctaa ataaggaggc ggcactgctg
    17161 aaaggtaaag gcacagtagt cgatgttgac ggtaaaaaga tgaatgtgta tcaagaggga
    17221 agcgggaagg atacgtttgt gtttatgtcc ggttcgggga ttgctgcgcc tgcttatgaa
    17281 atgaaggggc tgtacagcaa gttttcaaaa gaaaataaga ttgctgttgt agatcgggca
    17341 ggttatggat acagtgaagt gtctcacgat gacagagata ttgatacggt attggaacag
    17401 acgaggaaag cgcttatgaa aagcggaaat aagcctcctt atattttaat gcctcattcg
    17461 atatccggga ttgaagcgat gtattgggca cagaaatatc ctaaggaaat caaggccatt
    17521 attgcgatgg atattggatt gccccagcag tacgtcacgt ataaattgag cggagttgac
    17581 agattgaaag tgagagggtt ccacctgtta acctcgattg gttttcatcg gtttatgcct
    17641 tccgctgtat ataatcctga ggtgattcgg cagtcgtttt taactgatga agaaaaagaa
    17701 atctataaag ccattaactt taagcaattt tttaatgcag atatggagca tgagctttta
    17761 cagtcttacc aaaacggcag caaatctgtg aatctgccgg caccaaagga aactcccgtc
    17821 ttgattttag atgcggtctc tgaccaaaat agacattcaa agtatgctat acaaaaccga
    17881 aaagactatg aagcgtttgc ggctcaattc aatactgccg atataaagga actgagggga
    17941 acacacagta tttatttata tcagcctgat caaatatata aactgtccat ggagtttatg
    18001 agaaaggttc gctaggatga agggatatca tattttaatc gtggaagacg atgtgatgat
    18061 tggtgaattg ctgcaaaaga ttttgcagcg tgagggatat cgtgtgatat ggaaaacaga
    18121 tggagcggat gtgctttcgg tgattcagaa ggtggatttg gtcattatgg atgtgatgct
    18181 gccgggtgaa gacgggtatc aaatgtctgc aaaaatcaaa gagctggggc tgggcattcc
    18241 ggtaattttt ctttcggccc gtaatgatat ggacagcaag cttcaaggtt tacagatcgg
    18301 cgaggattat atggtaaagc cctttgatcc gagagagctg ctattaagaa tgcggaatat
    18361 gcttgagcat cattatggga cctttacgca aatcaaacat ttgtatattg atgcggtaac
    18421 gaaaaaagtg ttcaatgaaa gcctgcatga tgaggtatta tttactgcga ttgagcggaa
    18481 aattttcttt tatttatatg aaaatagaga cagtatcctg acaaaggaac atttctttga
    18541 atatctatgg caactcgaag atagaaaccc gaatattgtc aatgtgcata ttaaaaaaat
    18601 tagagctaaa atcaatgatc aagcgggtga gatgattgaa aatatatatg gagaagggta
    18661 tcggctgaat accgttgtga agaaatgaag cttaagacaa aatatcagtt gttattgttt
    18721 acggccgtca ttagtgttcc aatgctattg ctggcggtaa gtgttttgat gtcggtgatt
    18781 tatgacagca tgtttaaacc gatgaatcat ggtatgccct ttcacaggtc gtttgcgtac
    18841 ccggcaatga tcgttgtatt tttgatatca ctcttattgt tagctttttt attttcaaag
    18901 tcgattcatt ctctgttgca taaaatcaat ctattaaatc aaaccattcg gcatttggcg
    18961 agtgatcaaa gggtgcccga taaaattgaa gtgaagcgtg ctgatgaaat cggggaactg
    19021 atcaagtcgg tcaatttgtt aattgaacgg acgacatatc gtgaactgga gctgagacag
    19081 caagaggaaa tcaaaaagga gcttttgcaa aaactgcggc atgacattaa tacaccttta
    19141 acggctctca ggctgcagtt attttatttg gaagaccaat gtcatggtca ggctgtattc
    19201 gaatcattgt atcagcaaat cgaatatatc tcggaattaa ccaatgaatt caatctatat
    19261 tccgctgaga cgctggaaag ctcttatatt gtaaatgaag aagtgcgtct aaacgagcta
    19321 ttagaaacag cggtgaaaaa gtgggattat ttatacagta tgagtgggat tgagctgcac
    19381 tataaggcgg cagatcaaga tgtgatatgg atgagcaacg cgttatggat gcaaaggctg
    19441 tttgataata tttttcaaaa tacgttaaag cattcaaaag ctgaaaagat ggaagtcacg
    19501 attgaacatg acaatgtttt tattcgtgat gacggtattg gatttgatcg gaatgagagc
    19561 agtgagggac ttgggttaaa gattattgag gatacatgca ggctgcttgc gattacttat
    19621 gagctgcata caaatgatag cggaacgggg ttcttgtttt caaaagagtg accccgctga
    19681 tgtttttctt tctcctataa aatttatata atagggagaa agaaatgggg tgaacagcat
    19741 atgtttaaaa aaatcatcaa aacgattaag tacctctcaa gcagttctag tgaccgatat
    19801 cgcagacacc ggcattacag cagcagccgg cgcagacatt atcgcagcta cagcagctcg
    19861 ggcaaaagaa gacactacga ccgttatggc ggcagtcatc gttacaaacg ccggagctac
    19921 agcagcagtt aatccaaaaa agttcttgtt ccgcttttgg gacaagggtt tttttatgtg
    19981 accgattgaa tggcccggtt tagatcctcg cgaatggaag cggtgtgctg atactcttcc
    20041 tcaatgccca ataatctttt cagcagcaag gttacttcct ttgtcagtgt taattcctcc
    20101 agccaagtgc cgtttttctt cttttttcct ttatattgag agtacagcag gaataacagc
    20161 gtttctccga gatcgaagaa gtcatcctgt tttcgtacct ttatttcctc catttcttca
    20221 ggagtcaatt gtttggcaag gccgaaatcg atgaggcaga gcctgccgtc attgatgatg
    20281 atattaggcg ttctgatgtc gctgtggaag ataaggcgat catgcaggta ttctataatc
    20341 tcaagcagct gcgaaatcag ttgtaatgcc ataagctctg tgaacggctg ttttcgaaaa
    20401 aataataatt cttctatatt ctctccctca atgaactgca tgacataata agcctgtccg
    20461 tctatgatga actcatctat gaagcccgga atttgcgggt ggtgaatgct attgagcagt
    20521 tttatttcct gttggaatcg gactttctct ttttcctttt tcgcttttgt cggccgaagc
    20581 tgttttaaga cataaggtgt ttgagttagg atatcggtgc acaaataaac caaaccgtag
    20641 cctcccatac cgaggcactc ttcgattttg tattgatgat ttaagataac gccgttcttt
    20701 agagggcggt caaatagcag tttttttaga agttttaatg ccatgtctgc acttcccttg
    20761 gttgtactga ctatagttta ccttctagac agagaataaa aaagagccgg atcaccggct
    20821 cggtataagt taaaactgct ttgtcacgtc gtattcataa tctatttttg cttttacgtt
    20881 gctcatcgtc gatctggctg tcgctaatgt attatattta aaactccata cctttgccac
    20941 actgagttga tctgacaaag agatatcata agaccctgaa gtcgagctgt ttacaagagc
    21001 acggcgccat tcgttgtttt cgctcgtcat gatcaggtgg cgtgtatttc cctggcttgg
    21061 tgtttgagtg gcggttgtct gaactctggt tacaatggca tcacgcggta tcccggattg
    21121 gtttgttaaa tcaaccttga tcacgctgga atcagaacct gaggggctaa ggcttgtatt
    21181 tcctttattt tcagcaacgc cgctgaattg gaatgttccg ctgcctgatt tgattcggtc
    21241 ttcaattgaa agtgtaaaat acatgtttcc ggtataggtg cctcgtgaca ctttcacata
    21301 aaaggtatcc gtcgtgtttt gggcgtctgc atttgcataa ataaaagaag aaaacgtatt
    21361 agggttaatg acttctgtcc cttgagaaac aggtattcta ttcttatcat aaatttcaat
    21421 tttcatccct gtatacgcgc tctggtatgt actcctcacg tatacttttt ctcccttatt
    21481 agccgtaaaa gtgaaatagg cttcatcttg accagcttcc agtattgttg tatcgatatt
    21541 tttatatttc caataaccga tcggcattgc ggtatcaaat gaattgtttc ctgtgatagc
    21601 agtgactccg gcagctgatg ccgaatacgt aaaggtgaat aagacagaca gcataacagc
    21661 gaatggaata agccattttt tcaccatgca aacaacctcc ttttatttcc atcatacata
    21721 ataacgattt aggtgtaaat aaatgttttt tgaggttaat atatacatta tctttgccga
    21781 taaaaaagaa taagagagaa tactcgggag ggaattcaat gcgtctgaat cggcaattta
    21841 tccgcactca gctgatggca cagaacatat tgagcaagaa tgcgcctgcc aaacgggaga
    21901 atgcgactga aaatccagcg gcagttctgg aaaaggcata cagcaggctt aagtcacaat
    21961 cttcaactgg gggaatcaat cagttcaatt attctaaaac cagcgtgtcg ggaaacagcg
    22021 gggcgttcag caaagtgtat caatcagcga attttcgaac agtgacagac acaggggaag
    22081 aaacagtgat tcaatcccaa aacccctatg aatgtgagag tgatatcaga atcaaaatac
    22141 tagatgaaaa atacagcagg atgaatgcga ttaataaaac aaagtctgat ccattaggct
    22201 atattaagga taagtaccaa aattcaaagt ctccttattt cagaagtgat ctgtcagctg
    22261 cagaaagaca ggccgcttac gataatgaaa cagaatggtt attcaaaggg aaggcgcaaa
    22321 actataacct tcaggatgct gtgtttcgga atgtcacatt tcatggggaa gtggaagctg
    22381 agaatgaaaa ggtgtatcag cggggacagg ttaaccagca gctgcaagta ctgttgaatc
    22441 gaaaccatat tcatattcca gaggggacag agctgacgtt tacaatcaca ccgattgact
    22501 atcaggtgcg ggtaagcggg acagacgatc aggatctgat caagcaaatt gagcaagtgc
    22561 tgcaatctgg agacaacagc aaagaactat ttttgcacat catgaaaagc caaagcagtg
    22621 attcagcaca attttccgaa gaggcctatc aaaagtatca ggctgctcgt gagatgtatg
    22681 aagttacagg ctaccatttg aaggatttag aagtgattga tgggcggtac gtcacgcctg
    22741 agggacgtga cttaatggat gtatataagg aagagcttga aaaagatcca gtgcagaaac
    22801 aaacggcttc ttatgctata tcttactatc gttcagagct cagtaaaatc gcggaagccg
    22861 ggtataatgc cattccggat ttcatcctat caattgatta cagcaatgga tctctgatag
    22921 atgtgggaca aagcaagagc tatgggaccg gagataccgg gtggcttgaa gcattaaagc
    22981 gtcaaacggg tgtgaattat taggtaagct gttcatgtag aacagcttat tttttatgag
    23041 aatctaaggg gtgtattaat ttcaatattc aaataatttt attgttttta tataaaagat
    23101 tttaaaagaa gtgaacgatt caaaactctg aacaaaggtg tttacctgaa aaaaacaatt
    23161 gtattttcca gagaaattta ttatgatgaa ataagtaatt taggagatta tataacaatt
    23221 ttaagtttga attttctgat tgttatcgct gattcatgtg aaggcaagca ggtctgctgt
    23281 tttctcattt atgttaggag gaggaagagg agtggcaaat aaagaattaa agaggggcct
    23341 gggcgcgcgc catattcaga tgatcgcctt gggcggtaca atcggtgttg gcttgtttat
    23401 gggttctgcc agcacgattt catggactgg cccatctgtc cttctggctt atgcaatatg
    23461 cggaattttt atctttttta ttatgcgtgc gatgggtgaa atgctgtatg tcgagccgag
    23521 cacaggctct tttgcgacgt tcggccatca atatattcat ccgatggcag gttatataac
    23581 agcatggagc aactggttcc agtggattat cgtcggcatg tcagaaatta tcgctgtcgg
    23641 ttcttatatg aagtattggt tcccggattt gcctgcttgg atacctggta tcgtggcaat
    23701 ggtgattctt ggtgcggcga atttaatttc tgttaagtcg tttggggaat ttgagttttg
    23761 gtttgcgatg attaaaatcg tgacgattat cttgatgatt attgcgggaa tcggaattat
    23821 tttcttcggt tttggcaatg gcggagatgc gatcggtttg tcgaacctgt ggtctcacgg
    23881 gggcttcttt gcaggaggtt tctcaggttt cttctttgca ctgtctcttg tcattgcggc
    23941 ctatcaagga gttgagctga tcgggattac agcgggtgaa gcaaaggatc cgcaaaacac
    24001 gctaagaaat gcgattcaaa gtattatctg gcgtattttg attttctaca ttggcgctat
    24061 ttttgtgatc gtgacggtgt atccttggga tgagctcaac tcactcggaa gtccgtttgt
    24121 gtctacgttc tcgaaaatcg ggattacggc agcggccggc attattaact ttgtcgtgat
    24181 tactgcggca atgtccggct gtaacagcgg tattttcagc gcgggccgca tgctgtatac
    24241 actgggtgtc aatggacaag caccgaaatt ctttaagaag atttcacgca atggtgtgcc
    24301 gctgtatggc acaattgcgg tgctgatcgg tttggctgtc ggtgttgtac tgaactatat
    24361 cgcgccgccg aagatctttg tctatgtata cagcgcaagc gtgctcccag ggatgattcc
    24421 ttggtttatc attttgatca gccatatcgg attcagaa
//
