GCA_001699865.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaJKFIHHCI_7 (original name was: gnl|Prokka|JKFIHHCI_7)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	RRE-containing	12,742	33,095	polysaccharide C	Saccharide	16%

gnlProkkaJKFIHHCI_17 (original name was: gnl|Prokka|JKFIHHCI_17)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	phosphonate	5,259	18,818	polysaccharide B	Saccharide	13%

gnlProkkaJKFIHHCI_34 (original name was: gnl|Prokka|JKFIHHCI_34)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	phosphonate	24,528	42,312	polysaccharide B	Saccharide	33%

gnlProkkaJKFIHHCI_67 (original name was: gnl|Prokka|JKFIHHCI_67)

Region	Type	From	To	Most similar known cluster		Similarity
Region 12.1	lanthipeptide-class-i	443,575	473,778

gnlProkkaJKFIHHCI_97 (original name was: gnl|Prokka|JKFIHHCI_97)

Region	Type	From	To	Most similar known cluster		Similarity
Region 27.1	NRPS-like	322,065	364,494

No secondary metabolite regions were found in these records:: gnlProkkaJKFIHHCI_1 (original name was: gnl|Prokka|JKFIHHCI_1); gnlProkkaJKFIHHCI_25 (original name was: gnl|Prokka|JKFIHHCI_25); gnlProkkaJKFIHHCI_42 (original name was: gnl|Prokka|JKFIHHCI_42); gnlProkkaJKFIHHCI_53 (original name was: gnl|Prokka|JKFIHHCI_53); gnlProkkaJKFIHHCI_61 (original name was: gnl|Prokka|JKFIHHCI_61); gnlProkkaJKFIHHCI_64 (original name was: gnl|Prokka|JKFIHHCI_64); gnlProkkaJKFIHHCI_65 (original name was: gnl|Prokka|JKFIHHCI_65); gnlProkkaJKFIHHCI_66 (original name was: gnl|Prokka|JKFIHHCI_66); gnlProkkaJKFIHHCI_68 (original name was: gnl|Prokka|JKFIHHCI_68); gnlProkkaJKFIHHCI_69 (original name was: gnl|Prokka|JKFIHHCI_69); gnlProkkaJKFIHHCI_70 (original name was: gnl|Prokka|JKFIHHCI_70); gnlProkkaJKFIHHCI_71 (original name was: gnl|Prokka|JKFIHHCI_71); gnlProkkaJKFIHHCI_72 (original name was: gnl|Prokka|JKFIHHCI_72); gnlProkkaJKFIHHCI_73 (original name was: gnl|Prokka|JKFIHHCI_73); gnlProkkaJKFIHHCI_74 (original name was: gnl|Prokka|JKFIHHCI_74); gnlProkkaJKFIHHCI_75 (original name was: gnl|Prokka|JKFIHHCI_75); gnlProkkaJKFIHHCI_76 (original name was: gnl|Prokka|JKFIHHCI_76); gnlProkkaJKFIHHCI_77 (original name was: gnl|Prokka|JKFIHHCI_77); gnlProkkaJKFIHHCI_78 (original name was: gnl|Prokka|JKFIHHCI_78); gnlProkkaJKFIHHCI_79 (original name was: gnl|Prokka|JKFIHHCI_79); gnlProkkaJKFIHHCI_80 (original name was: gnl|Prokka|JKFIHHCI_80); gnlProkkaJKFIHHCI_86 (original name was: gnl|Prokka|JKFIHHCI_86); gnlProkkaJKFIHHCI_107 (original name was: gnl|Prokka|JKFIHHCI_107); gnlProkkaJKFIHHCI_116 (original name was: gnl|Prokka|JKFIHHCI_116); gnlProkkaJKFIHHCI_125 (original name was: gnl|Prokka|JKFIHHCI_125); gnlProkkaJKFIHHCI_131 (original name was: gnl|Prokka|JKFIHHCI_131); gnlProkkaJKFIHHCI_139 (original name was: gnl|Prokka|JKFIHHCI_139); gnlProkkaJKFIHHCI_140 (original name was: gnl|Prokka|JKFIHHCI_140)

Compact view

gnlProkkaJKFIHHCI_7 - Region 1 - RRE-containing

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Location: 12,742 - 33,095 nt. (total: 20,354 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

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core biosynthetic genes

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KnownClusterBlast

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaJKFIHHCI_17 - Region 1 - phosphonate

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Location: 5,259 - 18,818 nt. (total: 13,560 nt) Show pHMM detection rules used

Region on contig edge.

phosphonate: (phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))

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core biosynthetic genes

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KnownClusterBlast

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaJKFIHHCI_34 - Region 1 - phosphonate

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Location: 24,528 - 42,312 nt. (total: 17,785 nt) Show pHMM detection rules used

phosphonate: (phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))

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core biosynthetic genes

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaJKFIHHCI_67 - Region 1 - lanthipeptide-class-i

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Location: 443,575 - 473,778 nt. (total: 30,204 nt) Show pHMM detection rules used

lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03604))

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core biosynthetic genes

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KnownClusterBlast

Lanthipeptides

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Lanthipeptides

Core peptide predictions

No core peptides found.

gnlProkkaJKFIHHCI_97 - Region 1 - NRPS-like

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Location: 322,065 - 364,494 nt. (total: 42,430 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 322064 - 364494:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg27_281

AMP-binding (12..401): X

nrpys: Leu, Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALFLGVVLK
Nearest Stachelhaus code(s):: Leu or Ile DAIYLGVVLK (59% 8Å match); aIle DALVFGVVLK (56% 8Å match)
Stachelhaus code match:: 80% (moderate)