LOCUS       gnlProkkaCIEBMNNF_97   12151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CIEBMNNF_97.
ACCESSION   gnlProkkaCIEBMNNF_97
VERSION     gnlProkkaCIEBMNNF_97
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 03:56:16
            Original ID  :: gnl|Prokka|CIEBMNNF_97
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 4225
            Orig. end    :: 16376
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12151
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:7151]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7151
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12151
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12151
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             440..1834
                     /locus_tag="ctg58_4"
                     /transl_table=11
                     /translation="MQKLSIKQLIIITLGLLVLVMGLMTIHQRRHFNKNVKIDNVAVGG
                     LTAKQALKKLQDNPQTPKVYVNNDLVYTGKQPVAKFTQADEEKVANALHRQYTFFPSNK
                     DKNLLIKPQKFNQSVVPQVDQAVSQKVMELNNGRKAPINAYAVYENGQVQVRPAVGGTQ
                     YSLDGLHNQVEKELVQGEVKLKPIYKAPLSAKSKTVQNEKTKLEQIAKRDVTYQVQGKK
                     YHLTSADIITRATYQDGKYHFNTKVLGTKIDEINNQQATLGKPFEFKTHSGSVIKTTAA
                     GSYGWKISKKQAGKTLTNALIENKQTVNAKNDIYGKGYNQQGTGYNTTSNNGIGDTYAE
                     VSLADQHAWFYKNGKCVLSTDIVSGTNNKDNETPKGVWYIMYQQTPSVLRGLNDDGSKY
                     ASKVQYWSPFTDSGCGFHDASWRHDWSKQAYLAKGGGSHGCINMHPDVAGQAFSDLHKN
                     EPVVIY"
     CDS             1934..2122
                     /locus_tag="ctg58_5"
                     /transl_table=11
                     /translation="MDKVGVSYMVDLDLETKKNLVIINLFYIGLIALYCILHAGPLNFL
                     VFLGMLVLANIAEFVVK"
     CDS             2149..2280
                     /locus_tag="ctg58_6"
                     /transl_table=11
                     /translation="MLKKSYKFLSRKELSKVLGGWGYSLAFKSPRSWERAVLNWIKR"
     CDS             2277..3590
                     /locus_tag="ctg58_7"
                     /transl_table=11
                     /translation="MIHLTVGQGLTSSILNIIEIILIYQLVTSDFSLGLVIIDFLAVLM
                     IIFFSIVFFMLGSLYPVLIVFYFWLVDRIKSNSYIVINSILAMCISIVMASLFDLVDHY
                     TYTFFLQGKTDIALLGWLIPINDLIITIVVAILAVKVVRPKLRWIRINFPRPIGLWQIT
                     AILFMLYVWLTAIAEKDGVANKYASLLLIMYLIIIVVCATGFINFVKSSQQTQRQQQII
                     DKYQAQIASANQLNQQYNEIRRERHDTRNMLLSVQGYIRDHKDKEAEKLLATFLQNDTL
                     EKHYDEIDNALDKIKISGLHNLIKEKAYKIVEKGIPFSFEVNAEIDELPGSEIKTARII
                     GILMDNAIEATFKQAKPYIQFALLKHSPEVYELVIANSIEQKLNINTALKFEHSTKEGH
                     QGIGLSNVTQLVENDDHYSFSAEVKDKVIMMTCFIQGK"
     CDS             3598..4371
                     /locus_tag="ctg58_8"
                     /transl_table=11
                     /translation="MLKVIILENDDYQADYTERLVSQRKLINATPNSYDIELYLRTNDP
                     QEVIDSIKDEVYLAILDIELENQLSGIDVAEQIRKKAEFAEIIFITAYQEYLPYTVSHR
                     IEPFDYISKGEQIESIADRLRTDIDEAYARYQNYMNSNQKHQEKFTYEPTHGVKRQVDF
                     ENLYYIESVKNTNRRLRIVGKDIRIEYRGELGQVNNKHLLKVNQSTLINPKAIREFNRK
                     ERVVYFDENQEIKITVSYRKIKSLVNFLEKDNNGL"
     CDS             4387..4539
                     /locus_tag="ctg58_9"
                     /transl_table=11
                     /translation="MTKKAVIVSFYYQAILVNVFAFLLRILQKGLRILQNDTEKIFTYI
                     LMLES"
     CDS             4566..4724
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg58_10"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYRKLNFDELSKVSGGWSLSSQVNELVRDIVNSLNKWAQSCYAG
                     YHDSPFH"
     CDS             4737..4922
                     /locus_tag="ctg58_11"
                     /transl_table=11
                     /translation="MVKVRINKQFYKDFNFYFYMLFIVLWIKPLIDVENGYEFTYCLVF
                     LVGAIIATLLTIFKNK"
     CDS             5001..7151
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 321.7; E-value:
                     1.6e-97)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_12"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.2e-40, bitscore:
                     127.4, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 5.6e-276, bitscore:
                     907.7, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKINYLHYVAQVDEADCGVASLAMILRNFGSVYPIAKLRDLARTT
                     KQGTTALGLVKAAKHLGLDVIPIQADISLFDDPEITYPLIAHVIKDDLLHYCVVFKADQ
                     DYIYVADPDPATKVQKMTRDEFDRLWSGVCLLFSPAKGYTPQKEPLAGLTTMFQQLTNY
                     KKDISGIVIAAMLITFISIVGSYYLQLIIDRFIPSKNINGLTILAGSLLVVYVFNSLFN
                     YLRDVLLTRLDQKLTSQISLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSST
                     IISMFLDVGVMVIIGIVLSLYDRSLFLTTISTIPIYVIIIYAFNKRFAKLDQEQMESNA
                     QLSSAIIEDLKGVETLKVLQLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQY
                     GLVTIILFQGAILVIQDRLSIGTLMAFNALLAFFVSPLQNIINLQPKLQEAKVANNRLN
                     EVLQVDTEKSDTNSQDQTDLIGPINIQHVDYSYEYSHPILQDINLQIGCNDKLAIVGLS
                     GSGKSTLAKLLVGFYLPTQGQIEFNQHKTTEINLCDIRQYVHYLPQLPQLFSGTIKDNL
                     LMGLDREVSAEEIDNACKLALIYNDIQEMPLNYETKLDEEATALSGGQKQRLTIARALL
                     TSARVLIFDESTSSLDPITEKRIVENLLEIEDCTMIFIAHRLSIAKKVNKVVVMRDGKI
                     IEQGTHQELLNHHQEYYNLWNA"
     CDS             complement(7340..7525)
                     /locus_tag="ctg58_13"
                     /transl_table=11
                     /translation="MKIHFNKDFWRDGFFYIYLLLLFLWIAPFSDGSLPLDESLLCIFF
                     IIFTIGSMLAIMFNKD"
     CDS             complement(7804..8232)
                     /locus_tag="ctg58_14"
                     /transl_table=11
                     /translation="MSKYKVTATKTTTGMQVSAGTRGFEITFDEPESTNTGMNPVEILL
                     ASFGACQAITAQALAKKRNFDLRAFWVTIEGDLGREDVADGKNVRKFTEIRYQPHLRSS
                     ESDEDIKKFLADVAAKCPVENTLTYGTKFVQDGFVKVD"
     CDS             complement(8301..9296)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 298.7; E-value: 5.8e-91)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg58_15"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 4.5e-54, bitscore:
                     172.8, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKILMTSVRDDEQTAINEYAKEHNIEIITTPKLIDDAVELTADV
                     DGLVIQQRSKVPADIYEKLHTNGLKQIATRTAGFDMVDIKKANENDLVVTNVPAYSPRS
                     VAEFALMQIFRLLRKTYRFDHQVAENDFRWFSDEQSTEIHTATIGIIGVGRIGGTLAKL
                     LHALGATVLGYDTNPRTDLDGIVQFVSKEELLKQADVVSLHVDLNPTSKGLLTANDFEM
                     MKPTAGLVNASRGPVVNTADLVTALKKGTIAAAALDTFEGEETVAATNRREKGLDDQPL
                     VKELHEMDNVILTPHIAFFTNLAVKNMVDISLDDVMAILNGEKSPHEITL"
     CDS             complement(9298..10485)
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-387). E-value:
                     2.7e-73. Score: 239.0. Matches aSDomain:
                     nrpspksdomains_ctg58_16_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 275.6; E-value:
                     1.1e-83)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg58_16"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.4e-74, bitscore:
                     239.1, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 6.1e-08,
                     bitscore: 22.5, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTKKEILNRLNNNFAKLTPGGIREFDYQASAIPGIIKLTLGEP
                     DFNVPAAMKQAAIDSINANDSHYAPGNGTLALRQAIAHFMQDRYELEYDPENEIAVTVG
                     ATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKILGGIPIEVDTSSDDFVLTPARLQS
                     VLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTVKSTNLIVIADEIYSELVYGATHT
                     SIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQELMKAVSAIHAMLVTAASNPAMAAA
                     VAAFGTDEGKTATQEMKDAYEQRRDFVVNSLQKLGFELINPQGAFYVFAKIPKQYGNDD
                     LKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATSMENLTGALDNIASFINKEN"
     aSDomain        complement(9325..10377)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg58_16_Aminotran_1_2.1"
                     /evalue="2.70E-73"
                     /label="ctg58_16_Aminotran_1_2.1"
                     /locus_tag="ctg58_16"
                     /protein_end="387"
                     /protein_start="36"
                     /score="239.0"
                     /tool="antismash"
                     /translation="IIKLTLGEPDFNVPAAMKQAAIDSINANDSHYAPGNGTLALRQAI
                     AHFMQDRYELEYDPENEIAVTVGATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKIL
                     GGIPIEVDTSSDDFVLTPARLQSVLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTV
                     KSTNLIVIADEIYSELVYGATHTSIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQEL
                     MKAVSAIHAMLVTAASNPAMAAAVAAFGTDEGKTATQEMKDAYEQRRDFVVNSLQKLGF
                     ELINPQGAFYVFAKIPKQYGNDDLKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATS
                     MENLTGALDNI"
     CDS             10991..11212
                     /locus_tag="ctg58_17"
                     /transl_table=11
                     /translation="MRIDIKHYLEVNHLTIYQVSKRSGYGYTTLHKSFNKPQSSSTSLN
                     LRDLDALARAQDKSMWKVLKELEEHYLE"
ORIGIN
        1 ttatttcctt agctcgtcag cagcttggaa agccatatgt atacggggca acgggtccta
       61 attcatttga ttgctctgga ttggttcaat acgtttatcg tcaggcagga gttaacttac
      121 cacggacagc tgcccaacaa tctaaccaag ggtacagcgt cagcatgaat aacttacaac
      181 caggggatct cttattctgg ggtaatccag gaagtgcata ccatgttgga atttacactg
      241 gaaatggtaa gactttattt gcaccacaac ctggtcaaac agtaaaagaa caaccaatga
      301 gttactggat gccaaacttt gctcgtcgtg ttttgtaata aaaatattat ttttttgttt
      361 aatatagaaa accctactgc tataattatt agcgtgtagg gcatttctat tatttaactt
      421 attaagttgg agtactttta tgcaaaaatt atctattaaa caactgataa taatcacatt
      481 aggtttgcta gtactggtaa tgggtttgat gacgattcat cagcgccggc actttaataa
      541 aaatgtcaaa attgataatg tagcggtcgg tggtttaacg gctaagcaag cactaaaaaa
      601 attgcaagat aacccgcaaa cacccaaagt atacgtgaac aacgacctag tttatacagg
      661 aaaacaacca gttgctaaat ttacccaagc tgatgaagaa aaggtggcta acgccttgca
      721 tcgtcaatat accttttttc catctaataa ggataaaaat ttgctgatta agccacaaaa
      781 gtttaatcaa agtgttgttc cacaggttga tcaggccgtt agtcaaaagg taatggaact
      841 aaataatggg cgcaaagcac caattaatgc ttatgcggta tacgaaaatg gtcaagtaca
      901 ggttagacca gcagttggcg gtactcagta cagtttagat ggtttgcata atcaagtcga
      961 aaaagaactt gtgcagggag aggttaaact aaagccaatt tacaaggctc cgctttctgc
     1021 caagagtaag acagtacaaa atgaaaaaac gaagctagaa cagatagcta agcgggacgt
     1081 gacctatcaa gtccaaggta agaagtacca tttgaccagt gcggatatca ttactcgagc
     1141 tacttatcaa gatggcaagt atcattttaa taccaaagta ttaggtacaa aaattgatga
     1201 aatcaataat cagcaagcta ctttgggaaa gccatttgag ttcaaaactc acagtggatc
     1261 agtgattaaa acaacggctg ctggttcata tggttggaag atcagtaaga aacaagctgg
     1321 aaagactctt acgaatgcat tgattgaaaa taagcaaaca gtaaatgcaa aaaatgatat
     1381 ttatggtaag ggttataatc aacaaggaac tgggtataat accacaagta acaacggcat
     1441 aggggacact tacgccgaag tttcattagc cgaccaacat gcgtggttct ataagaatgg
     1501 taaatgtgtt cttagcactg acattgttag tgggaccaat aacaaagata acgagacgcc
     1561 gaagggtgtc tggtatatca tgtaccagca aacaccgtct gttcttcggg gccttaacga
     1621 tgacggttcg aaatacgcta gcaaagttca atattggtca ccatttactg atagtggatg
     1681 tggatttcat gatgcaagtt ggcgtcacga ttggtcaaaa caggcttatc ttgctaaagg
     1741 cggtggatcg cacggttgta ttaacatgca tccagatgta gctggtcaag cttttagtga
     1801 cttacataaa aatgagcctg tggttatcta ctaaaggagg agatgttgtg cgcccgagtg
     1861 ctgaacgcgc aattatgatt gcaatagctt gctttgtttt aacaattatt atttcttttg
     1921 cattatcaga gggatggata aagtaggagt tagttatatg gtggatttgg atttagaaac
     1981 gaagaaaaat ttggtaatca ttaacctttt ttatatcgga ttgattgcct tgtattgtat
     2041 tttgcatgca gggccactga attttttagt gtttttggga atgttagttt tggctaatat
     2101 tgctgaattt gtagttaaat aggtaattgt tatttattgg aggtaattat gttaaaaaaa
     2161 tcatataaat ttttatcaag gaaagaatta tctaaagtat taggtggttg gggatattca
     2221 cttgccttta aaagtcctcg ttcatgggaa agagcagttt taaattggat taaaagatga
     2281 ttcatttaac tgtaggacaa ggattaacgt catctatatt aaatattatt gaaataatat
     2341 taatatatca attggtaact agcgactttt cattaggatt agtaataatt gattttttag
     2401 cagtcttgat gattatattt ttttcaatag tattttttat gttaggatcg ctatacccag
     2461 tacttatagt attttatttt tggttagttg acagaataaa atctaattct tatatagtta
     2521 taaatagtat tcttgcgatg tgtattagta ttgtaatggc atctttattc gatttagtag
     2581 atcactatac ttatacgttt tttttacaag gaaagacaga tatagcactt ttaggatggc
     2641 ttattccaat taatgattta atcataacta ttgtagttgc aatcttagca gttaaagtag
     2701 ttcgtcccaa actgagatgg attaggatta attttcctcg accgataggg ttatggcaaa
     2761 ttacggcaat tttgttcatg ctttatgtgt ggttaactgc tattgccgaa aaggacgggg
     2821 tagcaaataa gtatgcctcg ctgttgttaa taatgtattt gataattatc gtagtgtgtg
     2881 caaccggatt tattaatttc gttaaaagta gtcagcaaac acaacgacag caacaaatca
     2941 tcgataaata tcaagcgcaa attgccagtg ccaatcagct gaaccaacaa tacaatgaaa
     3001 ttcggcgtga acgtcacgat acacgcaata tgcttctcag tgttcaagga tatattcgtg
     3061 atcacaaaga taaggaagca gaaaaattgc tagcaacgtt tcttcaaaat gatacacttg
     3121 aaaagcatta tgatgaaatt gataatgctt tagataagat taaaatttca gggttgcata
     3181 atcttattaa ggaaaaggct tataaaatag tcgaaaaagg tattccattt tcgtttgaag
     3241 ttaatgctga gattgacgag ttaccgggtt cagaaataaa aactgctaga attattggaa
     3301 ttttaatgga caatgcaatt gaagcaacct tcaaacaagc caaaccatat attcagtttg
     3361 cattgcttaa gcacagtcca gaagtttatg aattggtaat tgctaattcg attgaacaaa
     3421 aacttaatat taatactgca ctgaaatttg agcattcgac caaggaagga catcaaggga
     3481 ttgggctttc aaatgtgacc cagttagtag aaaatgatga ccattattct ttttcagcgg
     3541 aagttaaaga taaggtaatt atgatgactt gttttattca gggaaagtga gaataaaatg
     3601 ttaaaagtaa ttattttgga aaatgatgat tatcaagctg attatactga gcgtctagtt
     3661 tctcagcgaa aattgattaa cgctactcca aatagttatg acatagaatt atatttgcgg
     3721 acaaatgatc cgcaagaagt gattgatagc atcaaagatg aggtttattt agcgatttta
     3781 gacattgagc tagagaatca acttagtggg atcgatgttg ctgagcagat ccgcaaaaaa
     3841 gctgaatttg cggaaattat ctttataact gcatatcaag aatacttacc ttatactgtt
     3901 tcgcaccgga ttgaaccatt cgactatata tcaaagggag agcagattga gtcgattgcg
     3961 gatcggctcc gaacagatat tgatgaagca tatgctcgct atcagaatta catgaacagt
     4021 aatcaaaaac atcaagaaaa gtttacttat gaaccgactc atggagtaaa aaggcaagtt
     4081 gattttgaaa acctctatta tattgaatca gtaaaaaaca caaatcgccg gttacggatt
     4141 gtgggaaaag atattcggat tgaatatcgt ggcgagttag gtcaagttaa taacaagcat
     4201 ttgttgaaag taaatcaaag tacgctgatt aatcctaaag caatccgaga atttaatcgt
     4261 aaagaacgtg tggtttactt tgatgaaaat caggaaatta agataactgt tagttaccga
     4321 aaaataaaat cattagttaa ttttcttgaa aaggataata acggtttata aagttcaaaa
     4381 gaaactgtga caaaaaaagc tgtcatagtt tctttttatt atcaagcgat tttagtaaac
     4441 gttttcgctt ttttactacg aattctgcag aaaggtttac gaattttgca aaatgacaca
     4501 gaaaaaattt ttacttatat actaatgttg gaatcctaac tttatcgtat caggaggtaa
     4561 ttaaaatgac ttatcgtaaa ttaaactttg atgaattaag caaggtttct ggaggatgga
     4621 gtctctcttc acaggttaat gaactagtta gagatattgt taattccctg aacaaatggg
     4681 ctcaatcgtg ttacgcaggc tatcatgata gtccattcca ctaataagag gagaagatgg
     4741 taaaagtgag aattaataaa caattttaca aagattttaa tttttatttt tacatgttat
     4801 ttattgttct ttggattaaa ccgttaatag atgtagaaaa tggttatgaa tttacttact
     4861 gcttagtttt cttagttgga gcaataattg ctactttatt aaccatattt aaaaataaat
     4921 agtattttat aagaatataa agcccagaat cattattaat tttggacttt atttctttgt
     4981 ctgattagaa agcaaggtga atgaaaatca attatcttca ttatgtagcc caagttgatg
     5041 aagcagattg tggggttgcc tccttagcga tgattttgcg caattttggc tctgtttatc
     5101 caatcgcaaa attacgtgac ctagcccgga cgactaagca aggaactacc gccttaggac
     5161 ttgtaaaagc agcaaagcat cttggattag acgttatacc cattcaagca gatatatcat
     5221 tgtttgatga tcctgaaatt acttacccat tgatcgcgca tgtgattaag gatgatttac
     5281 ttcattactg tgttgtcttt aaggctgatc aagattacat ctatgtagct gatccagatc
     5341 ctgctacgaa agtacaaaaa atgacgcggg atgaatttga tcgtttatgg tcaggcgtat
     5401 gtttgctttt ttcgcctgct aaggggtata caccgcaaaa agaaccttta gctggattaa
     5461 cgacgatgtt tcaacaatta actaattata aaaaagatat atccggaatt gttattgcgg
     5521 caatgctaat tactttcatc agcatcgtcg gttcatacta tctccaatta attattgatc
     5581 ggtttattcc ctcgaaaaat attaatggct taacgatcct tgctggtagt ttattagtag
     5641 tgtatgtgtt taattctctt tttaattatc tgcgggatgt tcttttgact aggctggatc
     5701 aaaaactgac atcacaaata agtcttagat atattcacca tgtttatcgt ctaccgatgc
     5761 gatttttctc cacaagaaaa acgggagaaa ttacttcacg gtttaatgac attaataaga
     5821 ttattgatgc cttatcaagc actattattt caatgttctt agacgttggc gtgatggtga
     5881 ttataggaat tgttctttct ttatatgatc ggtcattatt tttaactaca attagtacca
     5941 ttccgattta tgtcattatc atttatgcct ttaataagcg ctttgctaaa cttgatcagg
     6001 aacagatgga gagtaatgct caattaagtt ctgcaattat tgaggattta aaaggcgtag
     6061 agacgttgaa agtgctgcaa cttgaaaata tccgttataa aaatgttgaa aagcaatttg
     6121 cggatttttt acgaaagaat ctaacatatg ttaaaactaa atcttttcag gatgcaatta
     6181 aaatgtggat tcaatacggt ttagtaacaa tcattctttt tcaaggagca attttggtaa
     6241 ttcaagaccg attaagtatt gggacattga tggcctttaa tgcattatta gccttttttg
     6301 tcagtccgtt gcaaaatatt attaatcttc aacctaaact ccaagaagct aaagtagcga
     6361 ataatcgatt gaatgaagtt ctgcaagttg ataccgaaaa gtcagatacg aattctcagg
     6421 atcaaacaga tttaataggg ccgataaaca ttcaacatgt tgactattca tatgaatata
     6481 gtcatccaat tttacaagat atcaatcttc aaattggttg taatgataaa ttggcaattg
     6541 tagggttgag cggttctggt aaatcgacct tggcaaagtt gttagttggc ttttatttac
     6601 ctactcaagg gcagatagaa tttaatcagc ataagacaac agagattaat ctttgcgata
     6661 ttagacaata tgtgcattac ttaccccaat tgccacaatt attttcggga acaatcaaag
     6721 ataacttgct aatgggatta gaccgtgaag tatctgctga agaaatcgat aatgcatgta
     6781 aattggcatt aatctataat gatattcaag agatgccctt aaactatgaa acaaaactag
     6841 atgaagaagc aactgcatta tctggtggtc aaaaacaacg cttgacgatt gcacgagcac
     6901 tcctaacttc tgcgcgtgtt ttaatttttg atgaatcaac aagtagctta gatccaatta
     6961 ctgaaaaaag aatcgttgag aatttgcttg aaattgaaga ctgcacaatg atttttattg
     7021 cccaccgtct ttcgattgct aagaaagtca ataaagtggt agtaatgcgc gacggaaaaa
     7081 tcattgaaca gggtactcac caggaacttt tgaatcatca tcaagaatac tataatttgt
     7141 ggaatgcata aaagaggctg ggagaaaact tttgttttct ctcagcccca actacttgtt
     7201 atgaacaata gaaagataac gtggaaaata accacaaggc tcgagtctaa gtacgaacga
     7261 taatcagccc gtgccgtgct aatcatcgtc ctagcttagc caaccgcctt gtcgaggagg
     7321 ttatttccca ctctcttttt cagtctttat taaacataat tgcgagcatc gaaccgatag
     7381 taaaaattat aaagaagata catagtagtg actcatctaa tggcagcgaa ccatctgaaa
     7441 atggtgcaat ccagagaaac aaaagtaata agtatatata aaagaaacca tcccgccaaa
     7501 agtccttatt gaaatgaatt ttcattagtt ctccccctaa gacagtatgt gtaccttatt
     7561 ataatgaaag atctaattta aaggacattt tgcaaaattc gttaagtttc ttgcagaatt
     7621 cgtataggtt gcctatttag aaagggactg tgacataagc gaagttactt tcataaaaaa
     7681 acaaatggcg cagtacacca atggcctcca acgctcggta aaaccgaatg ttggaggcct
     7741 attgttgctt gcgggggctc gaaaacgaag tcacgagtga cttctgtctc gctccctttt
     7801 caactaatca acttttacaa atccatcttg aacaaatttc gttccgtagg tcagagtgtt
     7861 ttccacggga cactttgcgg caacgtcagc gagaaacttc ttgatgtctt catcagactc
     7921 gctgctgcga agatgtggtt ggtaacggat ctcagtaaac ttacgaacat tcttgccatc
     7981 agcaacgtct tcacgaccaa gatcaccctc gattgttacc caaaaagctc gtaaatcaaa
     8041 gttacgcttt ttagctaatg cttgggcagt gattgcctga caggcaccaa atgatgcaag
     8101 gagaatttct actggattca tccccgtatt tgtactttct ggttcatcaa atgtaatttc
     8161 aaaaccacgg gtaccggctg aaacttgcat ccccgttgtt gtcttagttg ctgttacttt
     8221 atatttactc atagccgttc cctcctttta atacccatag tgtaatcgag acgatacttt
     8281 tggtcaatga gggtgctcaa ttataaggta atttcatgtg gtgatttttc gccattaagg
     8341 attgccatca catcatcaag tgaaatatcc accatgtttt tgactgctaa attagtaaag
     8401 aaggcaatgt ggggagtaag aatgacatta tccatttcgt gtaattcttt aacaagcggc
     8461 tgatcgtcaa gtcctttttc tcggcgattt gtggccgcca ccgtttcttc accttcaaaa
     8521 gtgtcaagag ctgctgctgc aattgttcct tttttaaggg ctgtaactaa atcagctgta
     8581 ttaacgactg gaccacggct agcattgacc aagccggcag ttggtttcat catttcaaag
     8641 tcgttagcag tcaataaacc tttagaagtt ggatttaaat cgacgtggag actaacaaca
     8701 tcggcttgtt ttagtaattc ttctttagaa acgaactgga caattccatc gaggtcagtg
     8761 cgcggattcg tatcatatcc tagaacggta gcacctaatg catgaagaag ttttgccagg
     8821 gttccgccaa tgcgtccaac accaataatc ccaattgtgg cagtatgaat ttccgttgat
     8881 tgttcgtcgc taaaccagcg gaagtcattt tcggcgactt ggtggtcaaa gcggtaagtt
     8941 ttccgaagca accggaaaat ctgcattaat gcaaactcgg cgacactccg cggcgaatat
     9001 gctggtacat tggtcacgac taagtcattt tcgttagcct ttttgatgtc gaccatgtca
     9061 aatccagctg tccgtgtcgc aatttgtttg agcccattgg tatggagctt ttcataaata
     9121 tcggctggaa ctttactgcg ttgctgaatt acgagtccat caacatcggc agttaattca
     9181 acagcatcgt caatcaattt cggcgttgtg atgatttcga tattgtgttc ttttgcgtat
     9241 tcgttaatgg cggtttgttc atcgtcccgc acactagtca tcaagatttt tgtcatgtta
     9301 attctcctta ttaatgaagg atgcaatgtt atcaagagct ccggttaaat tttccatact
     9361 ggtggcgtaa ctaattcgaa catatccttg gcccccagct ccaaagaagg aaccaggaat
     9421 cacagcaact tttccttcat tggcaagatc tgtcgcaaat ttaaggtcat cattaccata
     9481 ttgtttagga atcttggcaa aaacgtagaa ggctccttga ggattaatca gctcgaaccc
     9541 taatttttgg aggctattaa caacaaagtc tcgtcgttgc tcataggcat ctttcatttc
     9601 ttgagtagct gtttttcctt cgtcagtacc aaatgcggct actgcagcgg ccattgctgg
     9661 attagaagca gcagttacta acatcgcgtg aatggcactg actgctttca tcaattcttg
     9721 cggcccagcg ataaaaccaa ttcggtaacc agtcattgca tgtgactttg aggcaccatt
     9781 taaaattagc gtttgttcgg ggatgtaatt agcgattgaa gtatgagtag ctccgtaaac
     9841 aagttccgag taaatttcat ctgcaattac aatcaggtta gttgatttaa ctgtatcggc
     9901 tagtgcttta atttggtctt gggtgtaagt aacaccagtt gggttggagg ggtagttaag
     9961 aactagtcct tttgcgttag gatgttcttc tagtacgctt tggagtcttg cgggtgtgag
    10021 aacaaaatca tcgctgcttg tatcaacttc gatcggaatc ccacccagaa tctttgtgac
    10081 agccatgtag aaggggaaag ttggagttgg aatgataatt tcgtcgccag gattaataat
    10141 agtagaaaga gaagcgaaaa ttccctctgt tgcaccaact gtaacagcaa tttcgttttc
    10201 cggatcgtat tccagctcgt aacgatcttg catgaagtga gcgattgctt ggcgtagtgc
    10261 taaggtccca tttcccggag catagtgtga atcattggca ttgatgctat cgattgcggc
    10321 ctgcttcatt gcggctggca cattaaagtc tggttcacct aatgttagtt taatgatgcc
    10381 agggattgcg ctggcttggt aatcaaattc gcggatcccg ccaggagtga gtttagcgaa
    10441 attattgtta agacgattaa gaatttcttt tttagtagtt ggcatgataa attcctccta
    10501 tataatatgt agatttagaa aaaagaagcc ctgaatgcta taggaaaaac atccagggct
    10561 tcttgatcag attggaatga gtataaaaga ggctctcgga tgtttggggg tcatccggga
    10621 acatcacaat gataaaatca ctgctggtta gcggacggta atcgcgctaa accagaagac
    10681 atacgcttga ttcaagtgaa ttgtcgcagt gctcatcatt gtgtcctcct tttgattaac
    10741 tgattattaa taattctaat tattttttaa tttttgtcaa gagttgattg agaaaaacta
    10801 ttaattacaa aattatttat tgatgacaaa tgtaaatata ataaagtgtg aaaatgtttg
    10861 tgattattag ttcgccttta atttaatatt aaatttatat tctacaattt tttttatttt
    10921 tttcgtgtct tttttgttgt cttactccac aaatgtgata taatattaat cgtaaaggaa
    10981 gtgggtagca atgcggatcg acatcaaaca ttatttggaa gttaaccact tgaccattta
    11041 tcaagtttcc aagcgttccg gttacggcta cacgacttta cacaaatcgt ttaacaaacc
    11101 acagtctagt tcgacctcgc ttaacctgcg tgatcttgat gccttggctc gtgctcagga
    11161 caagagcatg tggaaggtcc ttaaagaact agaagagcat tacctcgaat gagattgtgg
    11221 ctttgctgta gccacaggaa gttaaatgcg ttaacttttg acttctagaa tacttagact
    11281 acgaaactta gaaaacaaaa tattatattt aattgaggag ggattgcata tggctcaaaa
    11341 cccaatgaat ccatttgaca acgacatgaa tgacatcttt aatcaattaa tgggtggcat
    11401 gaatggtttc aattctgata atcggcgtta cctaatcaat ggtcgtgaag taacaccaga
    11461 agaatttgct gaatatcgta gaactggtca attgccaggc ggtgcaaatc ctcaacaagg
    11521 tgggcaacct ggccctcaac ctaacgcagg taaggacagt atcttacaca agttaggtcg
    11581 aaacttaact caagaagctc gtgaacatga acttgaccct gttattggtc ggaacaagga
    11641 aatccaagaa acagctgaaa ttttaagccg gcggacaaag aacaaccctg tattagttgg
    11701 ggacgctggt gttggtaaga ctgctgttgt tgaaggatta gcacaagcaa ttgtttccgg
    11761 cgatgtacca gctgctatca aggacaagga aattatcagt attgatattt ctggccttga
    11821 agcaggtact caataccgtg gtagctttga agaaaacatg caaaagttgg ttgatgaagt
    11881 caagaaggct ggaaatatca tcctcttctt cgatgaaatt caccaaatta ttggtgccgg
    11941 ttcaactggt gattctagtg gttccaaggg tatgtctgac attattaagc cagcattatc
    12001 ccgtggtgaa ctaacagtta tcggtgcaac tactcaagat gaataccgga acactattat
    12061 gaaggatgct gcattagcac ggcggttcaa ttctgttact gttaatgctc caagcaaggc
    12121 tgatacagtg gccatcctta aaggtatccg t
//
