LOCUS       gnlProkkaDLLLPEHC_5    13962 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DLLLPEHC_5.
ACCESSION   gnlProkkaDLLLPEHC_5
VERSION     gnlProkkaDLLLPEHC_5
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 20:20:46
            Original ID  :: gnl|Prokka|DLLLPEHC_5
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 4258610
            Orig. end    :: 4272572
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13962
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8962]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8962
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..13962
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13962
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="2"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(940..1608)
                     /locus_tag="ctg5_3885"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKEWKYR
                     "
     CDS             complement(1754..1918)
                     /locus_tag="ctg5_3886"
                     /transl_table=11
                     /translation="MITDYTSTYFDFLLVNKPVIFNFYDIEEYRRVRGFSFEPIEFFVQ
                     VILFTIIMN"
     CDS             complement(1915..2538)
                     /locus_tag="ctg5_3887"
                     /transl_table=11
                     /translation="MLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDY
                     HMGDHSYDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNN
                     CNVIKREISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFN
                     AALILKLHPLQNKTVLKKIYPKVYLFLNKHINMDCMIFCHFQME"
     CDS             complement(2612..2872)
                     /locus_tag="ctg5_3888"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKIVLNIIKYMLKFMILLVFQNIKNIFMA"
     CDS             complement(2989..4308)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_3889"
                     /sec_met_domain="Polysacc_synt (E-value: 4.8e-29, bitscore:
                     100.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGSFLYVFLSLKLI"
     CDS             complement(4511..4654)
                     /locus_tag="ctg5_3890"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             complement(4651..5052)
                     /locus_tag="ctg5_3891"
                     /transl_table=11
                     /translation="MHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHSGINE
                     IGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFRICAL
                     GEIEVDDIENFFKVLKAALNHYNVTLPMS"
     CDS             complement(5001..5771)
                     /NRPS_PKS="Domain: Aminotran_5 (29-214). E-value: 2.8e-28.
                     Score: 90.7. Matches aSDomain:
                     nrpspksdomains_ctg5_3892_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 67.4; E-value:
                     1.8e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_3892"
                     /sec_met_domain="Aminotran_5 (E-value: 1.4e-23, bitscore:
                     81.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKNIPSV
                     LTIVIFICSMRILREQVKCILLHRYKLFTPLVRH"
     aSDomain        complement(5130..5684)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg5_3892_Aminotran_5.1"
                     /evalue="2.80E-28"
                     /label="ctg5_3892_Aminotran_5.1"
                     /locus_tag="ctg5_3892"
                     /protein_end="214"
                     /protein_start="29"
                     /score="90.7"
                     /tool="antismash"
                     /translation="CPREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDIC
                     LNSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPD
                     IAMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMAS
                     AQKGLQAMTGLSFIIGNEEQIK"
     CDS             complement(5781..5915)
                     /locus_tag="ctg5_3893"
                     /transl_table=11
                     /translation="MKQLPKLCGPVLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             complement(5912..6904)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 48.9;
                     E-value: 7e-15)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_3894"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.7e-18, bitscore:
                     64.2, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.2e-15, bitscore:
                     54.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGADISILILFVQKLKLKKQ"
     CDS             complement(6921..8222)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_3895"
                     /sec_met_domain="CTP_transf_like (E-value: 9.1e-11,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 9.4e-119, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.1e-60, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             complement(8243..8962)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_3896"
                     /sec_met_domain="NTP_transf_3 (E-value: 2e-12, bitscore:
                     46.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAASMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             complement(9026..10174)
                     /locus_tag="ctg5_3897"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             complement(10185..12596)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 32.3;
                     E-value: 7e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg5_3898"
                     /sec_met_domain="Poly_export (E-value: 5e-16, bitscore:
                     56.9, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIQRLFSILLFCLMLGSGSLMAQSMSDSQVLEYVKDGIRQGKEQ
                     KQLASELARKGVTKEQAMRVKQLYEQQNNVNTSKSTGTDINESRLREETKKNTSDMLED
                     HPTTQDLARGDQVFGRNIFNTRNLTFEPSVNLATPANYRLGPGDEVIIDIWGASQNTIR
                     QQISPEGTINIQKIGPVNLSGMTVSAANDYLKNALNKIYNGLNNTTDPTSDIRLTLGNI
                     RTIQINVMGEVVQPGTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVY
                     EFIMKGNTQDDIRLQEGDVVIVPAYDVLVKISGKVKRPMRFEMKKDENLATLIKYAGGF
                     EADAYTRSLRVVRQNGEEYEVNTVKDIDYNIYKMRNGDVVTAEAILNRFTNKLEIRGAV
                     YRPGIYQLSGKLNTIRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGT
                     SPNLALMKNDILYIPSIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKEA
                     ASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRRSPG
                     YQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKK
                     RMGDVIRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIP
                     KNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKG
                     SGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             complement(12991..13569)
                     /locus_tag="ctg5_3899"
                     /transl_table=11
                     /translation="MILRKKKSLNAGPINGTGEGVAHSKRWYVALVRMHHEKKVSEHLD
                     KMGIENFVPVQQEFHQWSDRRKLVTSVLLPMMVFVHVDPKERMEVLSFSTVSRYMVMRG
                     ESSPAVIPDEQMARFRFMLDYSEESISMNSSPLARGEKVRVIKGPLTGLVGELVNVDGK
                     SKIAVRLNMLGCACVDMPVGYVEPIMAAV"
ORIGIN
        1 caagttttat cttagacttc tccacccctt tttctatata aagatcttca gtaccaagcc
       61 aacactctgc tatgcgaata tctcgaatca tacgattaac cccatctgga cctaaagagc
      121 caagctggtc tgttcctttc atatgccgat caattgttac atgcttttct ataatttccg
      181 ctcccatcgc tacagcagct gtagcagcag aaatacctat tgtatgatca gaaaaaccta
      241 tctcaaactt attgtaatgc ttcttcaaat atgttattgt acgtagattc aaattatttg
      301 gatgagttgg atactgagat acacaatgta gaatagctat attactatga tatctcgtta
      361 tcacatctaa tgcattgtca agttctcttt gaccagccat tcctgtcgat aatataatag
      421 gaatatgagt ttctgctaat gcttcaagca atggtaagtt agtcaaatca cgactagcaa
      481 cttttagcct atccggtgtg aacagtttaa gcaaagacag acatcctttg gcacataacg
      541 tctcgataaa atctaatcct aatgacttag catatttata aatctcaaaa tgcgcttgat
      601 catcaagctc aagaaaagca cgatgttcac cataagtacg cccaaaagaa ttaggattgt
      661 catatatttg attcatttga gaaacagcca attcttctga taaatctctt ttagtcattt
      721 taacagcatt cattggcatg aaatccatac caaaaacatc ctcatgtaca ggtcgtgaga
      781 ttaattcaat aatcaactta gccaagtcaa cagaaccatt atgattctgc cctatttcac
      841 caataatata agtattcttc attatttaga atttttttat ttgttgtttc atcagttgaa
      901 tgtattctgc atgtcttcga acatagtcta caatcacttc tatcgatatt tccactcttt
      961 ttcttgtaaa tccctatata ttctctgtgc tacagaaaaa tcttctaacg tatcaatcgt
     1021 gagtcgaata ttatgatgtt ttgacacgac tggagatcct gaaatccatt gaatattaaa
     1081 aagttcagga tgactatata tataattagt aacatgttca cgatacaata aatcatcagt
     1141 aaatcctata actcgcttca gcgcatcaag cgttacaaat tctccccaaa aaccgaaatg
     1201 agttttaatt gatggagtac catcaatatc aaaacttata taatcgttac aagatttcat
     1261 tgctatttcg accaattgcc ttgccgcatg tacatctaaa aatggattat cagaacatat
     1321 tcggaatata ccctgtatat caaaatattc agcaacatca atgaatcgtt ttaaaacatc
     1381 attctcctca cctctgaagc actttacccc taatgcaagt gccttctttt caataggttc
     1441 attgataaca gaatttgttg tagcaataat tactggaata ttcgatatag cagaaagctt
     1501 atgaaccatt aagtcaagaa tcgattgatt accatagaaa ggtttcaata tttttccagg
     1561 caaacgtgta gaacctaaac gtgcctgcac cacaaatgca taattcattt tatttattat
     1621 atttcattta aaaatatgtc acatattctc tttgttgaat tatcatcttg aaattgattc
     1681 atcaataaag aaatatgacg tcgatgttca gcatgaatat ctttcccagc cagaagtccc
     1741 atcacagcat ctatcaattc attataattg taaacaatat cacctgcaca aaaaattcta
     1801 ttggctcaaa tgagaaacct cttactctac gatattcttc aatatcgtag aaattaaata
     1861 tgactggctt atttaccaat aaaaaatcaa aataggtaga agtataatca gtaatcattc
     1921 catctgaaaa tgacaaaaga tcatacaatc catatttata tgtttgttca aaaacaagta
     1981 tacctttggg taaatctttt ttaagactgt tttattctgc aaaggatgta atttaagaat
     2041 taaagccgca ttaaacttca atagtatttt cgataacttc aacaaatcac aatcaacata
     2101 tccgagtatt gaacgcaaat taccttcagt aacagtctca taatcacgaa aagttggagt
     2161 ataaactata tatttagtta catcatatcc cgcaaatttc gaaatttctc ttttaataac
     2221 attgcaatta tttttcgata tcaacaaatc atttctggga aatcctaaga ctttgaattt
     2281 atcatatgag attccacaat ctattgaaat tattctagca cttaaacaag aagtagcaat
     2341 agagtaatca aatgagttac atgttgtatt acgaaattta tcataagaat gatctcccat
     2401 atgataatca tctttgaatg gagtataata ccccaaacaa ataatctgtt gagagcgttt
     2461 tttaaatgaa aaatcataat aaaaagtagc tgtaaaacat ttacttgctc tacaaaaaca
     2521 aaaaaaggca tacaacatat ccttaaaaga tactttatta aagaaaaacg tccaacacat
     2581 gcacataaaa aagtacacct aatattagga tttatgccat aaatatattc ttgatattct
     2641 gaaatacgag aagaatcata aatttcaaca tatattttat aatattcagc actatctttt
     2701 ttagcaaata atttaacaga acgagaacat tatctgacga ataatttata atatcatatt
     2761 tatctgttct acaattagga tgaggaataa aatacaatga tctactatca actggcacac
     2821 aatggttaat tatctttact attacttgaa aaatcttttt taatattttc atctatgttt
     2881 ttagttttaa tgatcaatgt taaaatacaa aaaaagaatc tagcttaaaa agaaaagaaa
     2941 gtaaaatata gaaggacatc ccagtaatac atccaatcac aatttttact atatcagttt
     3001 caaagaaaga aatacatata aaaacgatcc ccccattatg aaagagagta ttaaacttgg
     3061 aaatacatct ttaacttgca actttaaggt caaatcaata agagaattag tataatatgt
     3121 attcaaatat gtcgctatca gagagtaaat aactctaccc caacacatca cctcaagccc
     3181 aaatggaatt gacacaaaaa gaatgaatat agcaatcgtc ttttttatta tttcaagacg
     3241 taacgacaga tcagatcttc ctttaaccca taataaattc aaattaattt ggctcaaatg
     3301 atcaaacatc caatccaaac ataatatctg taaaagaata acaaccccag accatttatc
     3361 tgttaacaat agactaataa taggattagc caaaacaagt aaacctacca ttaaaggaaa
     3421 aattatatat gaggataatc tgatataatt tcgatatgcg tttgttaaac atttatcatc
     3481 atcttgaatg gaacttaaaa taggatacgc tactctagaa actaaagcat ttaaattatt
     3541 ggaaggaaaa atagcaaatt gttctgctct tgtatagtaa ccaagctcta caacagaaaa
     3601 cttttttcct attacaatgg tatacagatt acgatatact gtattgataa gacttgagat
     3661 caataattta gatccgaaat tgaataatct ttcaaaagaa cttttggaga aagtatgtaa
     3721 aggtttccaa tgaactaaac agtaaaacaa aattgtcaaa attatactat ttaagagagt
     3781 ttgccaaact aaagcccaaa ccccgcaacc gacataagcc atccatattc caatcacgcc
     3841 tgatataaaa gctgcaccta atgaaatttt agattgagtt ttaaagttta cagaaataat
     3901 taatttcgtt ctgtgaatag ccgataaagc atttattatc aacgacaatg ctataaaacg
     3961 aattacaaga actaaagtcg gcatattata aaagtctgca atcaaagaag ccgaaaaaaa
     4021 caatatacca tagaataata ctgcgacaag aatattaaaa taaaagacag tggcaaaatc
     4081 ctcttcagtt ctatcttttt tctggattaa agcatttgta aaaccgctat ctataaatac
     4141 ttgagcgact tgaagaaaaa tagctaacat cccgatcata ccataatccg atggtagtaa
     4201 caaacgagct aatattattt gaattataaa ctgtactcct tgtaaagaga aacgttctat
     4261 agcgctccac attattcctg atacagtttt ctgctttaga ttttccatta cttaaataca
     4321 gtataaaaac aactacattt accgatatca attatatttt tccaatattc tcactaattg
     4381 gttattatct tcttcgcccc ttaccgcaat tctaatatgg tctctcccac taaaagcaaa
     4441 ttaccctaca caaacattat ctcctataac taccgatgcc tttttataag aataaagaac
     4501 tcctaatgca tcacctcaaa ttaatattgc catatttgcc tactaagcga aagctacgaa
     4561 taggcactcc agaaataaca ctttccggat ggaagtgtat accacgaagg gaaaaataaa
     4621 aatgacgaat cttcaataat atttctgcaa tcatgacatc ggtaatgtga cgttataatg
     4681 atttaatgca gcttttagta ctttaaagaa gttctcaata tcatctactt ctatctctcc
     4741 taaagcacag attctaaaag tatcctcagt tgatatctta cctggataaa tcgtaaatcc
     4801 acgctcataa caataatcat gtattttctc aaaatcccag ttgggatctt ctgggtattg
     4861 aactgagaca accagtcctg actgccattc acgctttatt acacttttaa gaccaatttc
     4921 atttatacct gaatgaatag cctcaaaaac tcttttgtga cgggcaaact tagcttcttc
     4981 acccacttca aaatattcat ttaatgcctg acgagtggcg taaatagttt gtaccggtgg
     5041 agtaaaatgc atttcacctg ttctctcaaa attctcatac tgcaaataaa gattacaata
     5101 gtaagaacgc ttgggatatt ttttgaaaac ttaatctgtt cctcattgcc tataataaaa
     5161 gaaagacctg tcatcgcttg aagtcctttt tgagcagatg ccatacaaaa atccacatta
     5221 tctttctcta tatcaaaagg aatcatgccc aaagaagaag tagtatcgac gacaaattta
     5281 gcctgatatt tatgagctat agcgcccatc tcgcgaatag ggttcagaat tcctgtaccc
     5341 gtctcgtgat gagtagtata aaccatagct atatcaggat tttcttgcaa cacattttcc
     5401 accaccgata aatcaggacg ttcgtaaacg gaaaattcca aattaatatg aggcaaacca
     5461 taatattgac acacttctac agcacgggta ctatatgccc cattattcac tataagcacc
     5521 cttttgtctt caggaagaag agaatttaga catatatcaa tattgatggt tcctgagcca
     5581 caaaataata cagcggtatg tttttccaaa ttcccatgag caactctgac caaatcgtcc
     5641 cgaagttgtt tcatcatacc tgcgaattct ttctcgcgag gacaaatatc cggaacaact
     5701 tgtgccattt ttacactgtc agtagtagtg gcaggcccag gatttaataa tatttttctt
     5761 tctattttca tcgaatatat ttattttaaa aaatccataa aatgctcctt attctctata
     5821 ggagtagtcg tgggacgtcc caaattctcc cgagaatcta ttttaacctt tatttccaac
     5881 aaaacaggac cacataactt tggaagctgc ttcattgctt cttcaatttc aacttttgta
     5941 caaacagtat aagtatgctt atatccgctc cccggacaat agccggaata tctaaactaa
     6001 atcctaaagt aggctgtcct cctacagact cgtgagcacc attgttaaac aaaatatgat
     6061 aatagttttt aggagataaa tcgccaatgt tactaattgc ccctaaatgc ataataaatg
     6121 ctccatcacc atccaagcaa taaacaggtc tatcttgctt tgctatagca atacccaaag
     6181 agattgatga actatgtccc atagagccta ccgtgagaaa atcatgttca tgaccttgct
     6241 ctttcatttc tcgatattca aataactcac gagaaagctt gccagtagta gaaacgacca
     6301 ctgaattttc aggcagataa tccacaacta tttgcaaagc atcctcacga gataaaggat
     6361 aattacatcc gaactctttt tgaagtttat atttgccaaa aacatctttc cgaataatta
     6421 ttgcatgagg aatattctta gtttttgctg attgtatgat atcatggagc tgaataaatg
     6481 catcattctc atttgaatca agaattatat aaggaatccg cattgctttc aacaaatcta
     6541 aagttacctc accctgtttt ttatgctgag gttcatcttt tgttcccggt tcaccacgcc
     6601 agccaatcat caaaagcatt ggaaaactgt atacttgttc atctgcaaga gacagcagag
     6661 gattaacagt attacccaag ccggaatttt gcatataaac cacaggaacc ttacctgatg
     6721 ccatataata acctgaagca attcctacag ccgcaccttc attagcagct atgatatgtt
     6781 tctcacgtga agtatggtct gtgatatagg cacaaatatt ttttagtaat gagtctggaa
     6841 ctcctgtaaa aaaatcaacg tcatgactca gaaacgtttc ataaactttt tctacgctta
     6901 acataatgat attcctcttt ttatttagta cctggaatca gttccaatat ttcttttatg
     6961 ggcatacaca gttcgcgcac ctctaaagca cgttcattct ctaatattat ctttgcgaca
     7021 ttcatcatag caggataagc ggcacgaagc atatgattag cataaataat tatattcaca
     7081 ccccaatcac acaattcaga ctcataaata tgatcatatg tagtaggcac aaccacgata
     7141 ggtacatgag catactgttt tcgaaacgcc aaacaaaatt cttttatatc ttcacccgac
     7201 ttatttttgc tatgtatcat aataccgtcc gctcccgctt ggacatatgc aaaagctctc
     7261 tctaaagcat cacttaccgg ctttcccgct ataaggctct caatacgagc gataatcata
     7321 aaatcatcag taatctgaga tgcctttcct gctttgatct tattacagaa accttcgatt
     7381 gtatcttgag tttgaataac atctgtacca aacaatgaat tcttttttaa tccaacttta
     7441 tcttcaatta ttatagctga aattccatga cgttctaaag tgcgtactgt aaatacgaaa
     7501 tgttcaattt taccacctgt atctccatca aaaataatag gtttagtagt acactccaga
     7561 atattattca aatcttgcaa tcgggtagtt aaatcaaccg cctcaatatc aggtttacct
     7621 ttactggttg aatccgtaag gctactagac cacattccgt caaatacttc cctcttatcc
     7681 ccttttaata tttcctgatt ttcaattatc aagccacata gtccatcatg agcttccaaa
     7741 atacgaacta cgggtttggc atttatcaaa cgacgaagtg attttaaacg tacatcaggg
     7801 gttgtaccta tagccttaat atctttatcc aaagaagatg aattaattcc caaagtatat
     7861 ggaatttcga taacctttcc tccctgttca ttcatcactt caaatacgcg cacacgttct
     7921 tcacgtaaag gcccggtttt ccagtcgtca ccatgaatta tatagtcagg tttaatgcgt
     7981 ttgagattct caacatagct ccattcttct tgaggaacaa ctttacatac gcctttaata
     8041 ttctgaacta cctcttttcg ttgttcatag gtcagataag gaaggcgttt atgctccgca
     8101 atagctttat ctgtaagaag accaattata acatcaccgt atttagtagc ctcattaata
     8161 atgcggataa gtcctggatg cataatatcc gcagtcatcc caatataaac tgtcttactc
     8221 ataatttgat atattatttt aattaacaat acggaacaat atatttctct gcatattcca
     8281 aatctgatat gtcatcgatt tcataccatt tcagcccttc tactttatgc acataaacag
     8341 gagattgaga acaagatatt cgtagtaatt catactcata tcccaaattg ggttgttcat
     8401 caacaatact cgcataatca gcacacatta ttttgtaaaa ggaaccggat agtttatgga
     8461 tgccgaccaa ttcgccttta gcgtttagtt tattcttatt gacagaacat gaagaaaggc
     8521 gaaaattatc atcatgttcc acataatact gatcttgaaa ctttgtcact ggagttatta
     8581 gcattgcatc tgccgcagga cactccaata agctcattat tgcttgtttc tcaaaaatca
     8641 aatctgactc taacaataaa aaatcatcat tgcccagaat ctcccgcgta ttatataaag
     8701 tatacatact atttgtttca gcataacgag gactaaaaca ggtttcaagc ataggatagt
     8761 ctgtcttcaa ttcttcataa acttcttgtt tatatcctgt accgattaca attcgctcaa
     8821 tgtcacatga taacaaagta tcaatagaac gaactatcat tggaatacct cccactttga
     8881 cgaacccttt aggtatcaat tctgtatatt ggccaaaacg ggttcccatg ctcgcagcca
     8941 ttatcatagc tgtacgtatc attcgtttaa taatatagta agtgaattta attgatgtaa
     9001 gaatgttgta aacgacgttt tagcatcatt tatcctgttc tatctcctta tttttcagtt
     9061 cttttctcaa gctagccagc agacttttgc caaaaaacac ccacacgaga gtaccagata
     9121 cggacaggaa cacaaataat aaaatataaa ttttgagtcc catacctgaa ggtttcaaag
     9181 gtacaacggc aggctcaact actgcaaaga ctggcttttc ctcctgtact ttggctctgg
     9241 atacctgcaa ctgattagca acctgactat atatctgata agccaaactc atgtcgttct
     9301 gtaaacgctc ctgctcagca cgtacacttt gaagaaccac attatcatgg gcgtctacat
     9361 aatccgcata ttttctttga gcagcataat attcctgctg acgttcttta aacaaccgtt
     9421 ccaaatacgc acagtcttct tttacttttg aagttcgata cccaataata tattcctgta
     9481 atttatgaac gacagaatct gctataaccg cagtgatctg cggattttgt aaggtgaccg
     9541 taatgctcgt tatggcggtt ttcttatcaa tggatgcact aatcttcttt ttaagaaaat
     9601 taatcttctc atttacttct ttcgtcaatt cgatagttcc ttgccgccct ccactggcag
     9661 gaaccgtatc ttctccgaat aatgatttaa ctcctcctat tactatgccc ggaaaaccta
     9721 taagataatc ccaccaagga gatgactctt catcgagata agaccccaaa gtcattttat
     9781 catccttttt agaaacggag acttccattt ctaaaagttc caataaaaaa ggagttgaag
     9841 aaacaatatc tgctgaaaga gaagcgttca aggcatctgt gctttcccct attagagccc
     9901 catctcccaa aaacgaggca gcaagtccgg ctaaaccatt acttcccttc gcattaccca
     9961 tttcaggaga aagggtaacc tttactgtat attgcttggg aatgctcaat gccaccacta
    10021 tagcaattat tactcccact ccagcagctt tgcatagtac tccacgaaca gtaataatct
    10081 tataaaaaat agccatcaag tctatttcca tttcatcatc tttcctttta tccacttcag
    10141 aaaacggttc ttgataagat tgcttttcaa tcataatagg tcatttattt ctttatcaaa
    10201 ttagcaatag aagcaatcat cattcccaaa gaactgaagg aagtagcata acctaaaata
    10261 ttagctatgt tccctttctt cttagcctta ccaggcacaa taatctcaca ccccggctca
    10321 atctgtttct taccactacc cttaaccttc gtcacctgac cattcatgta aacaatgaac
    10381 ttcttactct tccttgcatt atcagaacag ccaccggcct gattcaggta ataatccaca
    10441 ttctttccct tcatataaga aaccgtattc ggaaccatga cagcaccatt gatagttaca
    10501 gtattagtat tcttaggtat ggagatcaca tcaccttcac gtaagacaag atcggcatta
    10561 cttttaggat tgctcaaggc tttttccaaa tctattccaa ccgtaaaagt atcttcaaca
    10621 cgaataccca aagagtcaat catggcttcg cccaattgcc tgctcataag gcgaattaca
    10681 tcacccatac gtttcttttc actagcgtta gccacacggg tcagtttcgc accacgcaga
    10741 taggcataat tggtcggacc gccggcttta ttcactaaat cggaaagacg ttcctcacgg
    10801 ctggtcatgg cgtaatttcc tccgaaaagg atttcacctt caatggctac attctgttgt
    10861 gcctgatagc ccggactgcg acggacataa acctgatcat aaggctcaag gataaaaccg
    10921 ggctgaccat ctattacaaa accatccttt aaagagaagg tatacatctg accaatcgta
    10981 tcattatccg cagtactacg aggattcttg attcgtctcg atatatcaat acggacagta
    11041 gaggcggctt ctttcaagcc accggcctga atgatcagat cctcaagtgt catgttatcc
    11101 gcataaggat aggaatcagg gtgggcaacc tcaccgtgaa ctgtgacatt accccggtct
    11161 tccaggtcat ggatacttgg aatgtagagg atgtcattct tcattagggc aaggtttggg
    11221 gaagtgccgt ccatgataga cttaatgtct atctgaacaa cttcactggt caggtcttca
    11281 cgctggcgat agaggacggc acgattcagg aaagcgtcac cggtcagacc ctgagcttca
    11341 tggacaagtt cgcggatcgt gttcagttta ccgctgagct ggtagatacc gggacgatag
    11401 acagcgccac ggatttccag tttgtttgtg aagcggttaa ggatggcttc ggcggttact
    11461 acgtcaccgt tacgcatttt ataaatgttg taatctatat ctttgactgt gttgacttcg
    11521 tattcctcac cattctgacg gacaacacgt aatgaacggg tgtaggcatc agcttcaaag
    11581 ccgccggcat atttaatgag agtagcaagg ttctcgtctt tcttcatttc aaaacgcata
    11641 ggacgtttta ccttgccgct aatctttacc aatacatcat aggcaggaac aatcacaacg
    11701 tcaccttcct gtaggcggat gtcatcctgt gtgttgcctt tcataatgaa ttcgtagacg
    11761 tcgatggtgg caatattctt tccgttgcgt accaactgaa cgtttcggag gctgccgata
    11821 tcactcacac cgcctgcacg ataaagcgca tggaagacgg tagagaagga agaaagggcg
    11881 taggtaccgg gctgtacgac ttctcccatc acattaatct gaatagtacg gatattacct
    11941 aacgtcagac ggatgtcgga agtaggatcg gtagtattat tcagaccgtt atatatttta
    12001 ttcagggcgt tcttcagata gtcattggcg gcagagactg tcataccgct aaggttgaca
    12061 gggccgatct tctgaatgtt gatagtacct tcaggagaga tttgctggcg gatcgtgttc
    12121 tggctcgcac cccagatatc aatgatgact tcatcaccgg gaccaagacg gtaattggca
    12181 ggagtggcaa ggttgacact aggctcgaac gtcaggttgc gggtattgaa gatgttacgt
    12241 ccgaagacct gatcaccacg ggcaaggtcc tgagtagtcg gatgatcctc cagcatatcg
    12301 gaagtattct tcttagtctc ttcacgcagg cgggattcgt tgatgtccgt gcccgttgat
    12361 ttcgaggtat ttacattgtt ctgctgctcg tatagctgct tcacacgcat tgcctgttct
    12421 ttggttacac ccttacgggc tagttcggaa gcaagctgct tctgttcctt gccttggcgg
    12481 atgccgtctt ttacatattc cagtacctgt gagtcactca tggactgagc cataagcgag
    12541 ccacttccca gcatcaaaca aaatagtaga atgctaaaaa gtcgttgtat tttcattgac
    12601 aaataaaaaa gtttcagttg atttcacaca gttcctgcat cccatgacag acggcagata
    12661 actgttgctt aagaagagaa gggggaagaa catcgagaag agacagagaa cgggtcaaaa
    12721 cagcctgttt tctttcttcg tcttccggat tggcgtacat cgacacatta tatccctgaa
    12781 ggatggccaa acacagggta gcatcctgct ccggtgtctc ccccgttgag aatataaatc
    12841 gttaatcttt tcgtggatgg atcgttgtaa tgctgaaaga tcatccaaat acacgcagcc
    12901 tgcactcccc caccaggaag cagcatacgt accaaactta ataaaccctc tatattttct
    12961 tgtaaaataa tagcatccat atcccttgcc ttaaacagcc gccataatcg gctctacata
    13021 accgacaggc atatcaacac aggcgcatcc cagcatattc aagcgaacag caatcttact
    13081 tttaccatcc acattgacca gttcgccaac aagacccgtc aacggacctt tgatcacgcg
    13141 aaccttttcg ccacgagcca aaggagaact gttcatgctt atcgattctt ccgaataatc
    13201 aagcatgaaa cggaaacgag ccatctgctc gtcaggaatt acagcaggac tactctcgcc
    13261 gcgcatcacc atgtaacggc tgacagtaga aaaactcagg acttccatgc gttccttagg
    13321 gtcaacgtgt acgaagacca tcataggaag caagacggag gtgaccagct tgcgacggtc
    13381 gctccattgg tggaattcct gttgaacggg aacgaaattc tcgataccca tcttgtccag
    13441 atgctcggaa accttctttt catggtgcat ccgaaccaaa gcaacatacc agcgttttga
    13501 gtgtgctacg ccttcccctg tcccattaat aggcccagca tttagtgatt tcttttttct
    13561 taaaatcata tttttttacc ccatgtttat ccgttacttc ttaggtaacg aacaagcata
    13621 gggcaagcag aaaagggaac ttttttcaac gaaaacatca gaagaggact ggtattcagg
    13681 aaataaagca gaagtgaagg tgtttttcat gaattggaat aaaaaaagac ataacacgga
    13741 tattgtcatt ttccgcctgt tatgcctgca tttgattcat tttccgaaat taatttcatt
    13801 tttgtttgcg tattttcata aatatgtcca tctttgcgcc atgaatcatt ccgttaccta
    13861 agaagtaacg cacaccgata aacactgtat atcaagcttc taaatcagat acactgacct
    13921 actccgcacc gctttacgta agacaaattc atccggttca cc
//
