LOCUS       c00108_gnlPro..        15459 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DOLIIFAH_126.
ACCESSION   c00108_gnlPro..
VERSION     c00108_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 05:02:31
            Original ID  :: gnl|Prokka|DOLIIFAH_126
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 10658
            Orig. end    :: 26117
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15459
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[20658:23954]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13296
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15459
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15459
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             939..1463
                     /locus_tag="ctg108_13"
                     /transl_table=11
                     /translation="MTTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVV
                     IGFAGGVADAFTLQDWFEKKLEHYAGNLRRSAVALAQDWRKDPTLQKLEAMMIVMDEHD
                     LLLVSGSGEVIDPDEDVVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGNIDI
                     FTNHNVIVESF"
     CDS             1507..2916
                     /locus_tag="ctg108_14"
                     /transl_table=11
                     /translation="MAEVQTPKQIVEKLDQYVIGQNDAKRAVAVALYNRYRRMQLSPKM
                     QEEITPKNLLMIGPTGVGKTEIARRLAKIVEAPFVKVEATKFTEVGYVGRDVESMVRDL
                     AETAVAMEEEKQFSKVRIRAEKEANKRLVKILVPAIRKEKNTNPMAEMMSMLQGMQNGK
                     MPAGDDADAGGEVTDDIRNKRLSVAEQLEKGLLEDHEITVAVNDEKKGGGMGDMYGQMG
                     IDLSDTIGALMPKKKVERTMTVKEAREIFIKEESDKLVNHADIYHDAIQSAENNGIIFI
                     DEIDKIAAGNKHNSGEVSREGVQRDILPIVEGSQINTKYGPINTDHILFIGSGAFAEAK
                     PSDLIAELQGRFPIRVELKDLTEKDFVRILTEPDNALIKQYIALIGADGVKITFTKEAV
                     DRIAEIATQVNHDTDNIGARRLATILEKLLEDVLYEGPDMAMGAVTVTQQYVDDKIGHI
                     AADSNMTRYIL"
     CDS             2952..3830
                     /locus_tag="ctg108_15"
                     /transl_table=11
                     /translation="MVTIANDFLTVKISRHGAELTSIKDNLTGRERLWQADPAVWGRHA
                     PVLFPIVGALADNQYHYAGKTYHMGQHGFARDRDFTVLSATPFKASFVLKDDDKTRAMY
                     PFAFRLIITFALENNNLHVTYHVDNPDKSEPLFFSIGGHPGFKVPMTPDTQFSDYYLNF
                     KPRKSLVQIPLVAGEGIDYTHRTLAATDANLALTHETFDHDALIFALLGKTTFNLVSDK
                     TKHGVSVTMTDTPYLGVWSPYPTTGDFVCIEPWWGIADTIGSTGDLTRKLGINRLEPGT
                     AFEKGYMISIF"
     CDS             complement(3912..4619)
                     /locus_tag="ctg108_16"
                     /transl_table=11
                     /translation="MYVRFILLTYHSKVKNAKIVSSLRGGAHLILVLCFILAYFIGAIP
                     FGVVIGKLFYHTDIRKGGSHNIGTTNAYRMLGPVGGSIVLVLDILKGTLAASLPILFGI
                     EHHWLVLIVGLAAVFGHTFSIYIRFKGGKAVATSAGILLAYNPPFFVIAFAIWFSLILL
                     TSMVSVASTLGMVLITAWSLVYHDWLLTTVACGLLVVFLIKHRANFKRIKAGDENMVPF
                     GLGQYLRQHRGRS"
     CDS             5337..7349
                     /locus_tag="ctg108_17"
                     /transl_table=11
                     /translation="MDKATQAYNDSSIQVLHGLEAVRKRPGMYIGSTDGRGLHHLVYEI
                     VDNSVDEALAGFGDEINVTIHADNSVTVQDHGRGMPTGMHPSGKPTIEVILTVLHAGGK
                     FNQNSYKTSGGLHGVGSSVVNALSESLTVRVVRDKHAFEEHFINGGHPDGSLQKLGKVN
                     EPNGTTITFKPDPTIFQTTVFSYDTLAERLRESAFLLKNITINLTDERTGKHDSYHYPD
                     GLVSFVKYLNEGKDALSQVINFEGKKDGIVVDFAGQYNDGYSENLISFVNNVRTGDGGT
                     HEIGLRSGMTRAFNEFARKVGLLKERDKNLEGSDVREGFAGILSVRIPEEILQFEGQTK
                     GKLGTPQARTVVDGIVYDKLSTFLMENGEESQELVRKAVKARDAREAARKARDDSRTGR
                     KRKKDQGLLSGKLTPAQTKNPKRNELYLVEGDSAGGSAKQGRDRKFQAILPLRGKVLNT
                     QKAKLQDIVKNEEINTMIYTIGAGVGADFDLQQANYDKIIIMTDADTDGAHIQILLLTF
                     FYRYMRPLIDAGRIYIALPPLYRLQKGAGAKTKISYAWTDEELAKETKAMGKGYTLTRF
                     KGLGEMNADQLWETTMNPETRTLIRVRIDDAQLAERRVTTLMGDRVEPRREWIEHNVKF
                     DMDDDGSILETPTANHEKLQFGAKQIVKQLDKKGK"
     CDS             7356..9800
                     /locus_tag="ctg108_18"
                     /transl_table=11
                     /translation="LANQIQELTLEEVMGDRFGRYSKYIIQERALPDVRDGLKPVQRRI
                     LFAMNQDGNTYDKGFRKSAKSVGNVMGNYHPHGDSSIYEAMVRLSQDWKLRAPLIQMHG
                     NNGSMDGDPPAAMRYTEARLSKISKEMLADIDKETVDMVLNFDDTAQEPTVLPAGFPNL
                     LVNGATGISAGYATEIPPHNLREVINAVLYLLKHPTADLDTLMQYVKGPDFPTGGIIQG
                     LDGIKQAYETGRGKIVVRSRTHIETIRGGREKIVVTEIPYDVNKAQMIKKIDELRINKK
                     VDGIAEVRDESDRFGLSVVIELKKEADAHGILNYLFKNTDLQIAYNFNMVAIADMQPKL
                     LGLKAMLEAYVEHRRDVVTRRTRFDLNKAAARQHIVEGLIKMLSILDQVIAAIRASKDK
                     GDAKRNLVKKFDFSEAQAEAIVSLQLYRLTNTDITALQKEAAQLAKAIAEYQDILARPA
                     ARDRVIEGELKRIAKEYGDDRRSSIQAKIETLEVATTVTVADETVMVQVSRDGYVKRSS
                     LRSYQAVDPADNGLKANDLAIFTGELSTLQHLYIVTNAGNVIYRPVHEISDARWKDTGE
                     HLSQTVGLGTDEKVLAVFAFDQLDGAGSFVLGSSDGYIKQTALSDLQPQRTYKSKPMMA
                     MKLKDPAAIVTNAYFTTDQQQDVFVVSRHAYGLTFPLSDVSTVGARATGVKSMDLKPDD
                     EVVNFILVKDPTTAKVGILTQRGAFKKMALSEVGEMSRARRGLLVLRELKRDPHRIVAM
                     MSVDDATRLNVLTDTGKVTTLNPAQHPAGDRYSNGSFVIDTDVLGKPVFVQTKEEPADQ
                     VE"
     CDS             10001..12313
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_19"
                     /sec_met_domain="Gly_radical (E-value: 9.4e-42, bitscore:
                     132.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 4.2e-244, bitscore:
                     801.9, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VFVRTVTSVIHFRRQTTMKQLDETKVPNYWEGFNGGDWQEEINVR
                     DFIEHNLNQYDGDESFLAGPTEATTVLNNQVLNLKKQERANGGVLDADNNIPSTITSHG
                     PGYLNKDLEKIVGVQTDKPFKRAFMPFGGIRMAEDALESYGFKTDPQEHKIFNEYRKTH
                     NQGVFDAYTPDMRKARHYKIVTGLPDAYGRGRIVSDFPRIAVYGIDRLMAEKFKDYNLT
                     GDGEMTDDVIKLREEINEQYRALNDMKKMAKEYGYDISRPAANAQEAVQWIYFGYLAAV
                     KTQNGAAMSVGRIDTVIDAYIQRDMRLGKLNEEQAQELIDHLVMKLRMVRFIRTEEYNS
                     LFSGDPIWATLSLAGMGNDGRHHVTKTAFRFLKTLDNMGAAPEPNITLLWSERLPEGFK
                     RYATEVSIQSSTIQYENDDLMRNEWGTDYYGIACCVSAQPIADGVQYFGARANLAKTVL
                     YAINGGKDEIQEAQVGPEYAPITSDYIDYKEFMNKFDKMMDWLADTYVNALNVIHYMHD
                     KYYYEAAQLALKDTQLNRTFATGISGLSHAVDSISAIKYGHVKAIRDENGVAVDFVADN
                     DDYPRYGNNDDRADDIAKWLVKTFYNKMNTHHLYRGAKLSTSVLTITSNVVYGKNTGTT
                     PNGRQKGEPFSPGANPAYGAEKNGALASLMSTAKIPYHYATDGISNTFGVTPNTLGHDD
                     ETRKDTLVHMVDGYMENSGMHLNINVFNKETLIDAQKHPEEYPTLTVRVSGYCVYFADL
                     TKEQQDDVIARTFFEEM"
     CDS             12279..12410
                     /locus_tag="ctg108_20"
                     /transl_table=11
                     /translation="MSLLGPSSKKCKQLNSRQEVIPVLPKDGNDAVAVFWQNEMKIN"
     CDS             12445..13296
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 65.2;
                     E-value: 2.4e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_21"
                     /sec_met_domain="Radical_SAM (E-value: 6e-26, bitscore:
                     82.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLIDQSQSPLNILEQVGQDHDGPIKGYVHSVESFGSVDGPGIRF
                     VVFMQGCRMRCQYCHNPDTWNIGVGEEMTADQILADAQRYKAFWGDQGGITCSGGESLV
                     QIDFILELFTKAKALGISTCLDTSGGPFTRDQPWFGQFEKLMAVTDISLVDIKHIDSAE
                     HKKLTGFPNENILDMVQYMSAHGDDMWIRHVLVPERTDFDPYLKRLGDYIATLDKNVVQ
                     KVEILPYHTLGVKKYHELGITYPLEGIEPPSADRVKNAENLLHVKDYTGWQSWRPKPVA
                     SN"
     CDS             13421..14389
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     60.8; E-value: 3.2e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg108_22"
                     /sec_met_domain="LysR_substrate (E-value: 3.5e-27,
                     bitscore: 85.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.2e-19, bitscore: 60.8,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKQERIFSSKTLTYFLQLAETMNYTQAAQLLGITQPALTQQIK
                     KLERTVGAPLFYSVGKKLHLSDAGQTMLKSTHEIYEILNQTTDEIQQTTSATVGKINIG
                     LLSSIEDSAFIAFIAHYYQLNPEVEVTLRMMTRHEIWESLENNQIDLAIMNLPDETIKN
                     WKPYASKKIIDEQLLFLHHDDALANRKRIHFKDTLAEPWATYPDDYFLGQLLREAYKNQ
                     MVDFPHVVAHFTTPYQLTQFVNLSGVNTALPTSFVRARADQIKAYAIAFDPAIRFEISF
                     VYRKEKADIPRISNFFQTFDDYLKEKDYLSRVSENRVKLDK"
     CDS             14419..15351
                     /locus_tag="ctg108_23"
                     /transl_table=11
                     /translation="MTTLIFGHQNPDTDAITSAMSWAEFQKQAGNTDVEAVALGEPNDE
                     TKFVLDHFKVQAPRVIKTAANETDHVMLVDHNEFQQSVSDIEDVTIDSVVDHHRIANFH
                     TAAPLFYRAEPVGSTNTVIFEMFQEYGFKISPTLAGLMASGLISDTLLLKSPTATDKDK
                     KILPEMAKIAGIDLQSYGLAMLKAGTNLAAKSDMDIIEGDAKSFTMGGKSIRIGQVNTV
                     DLNDIYARQDELINAMTKEAQAKGYDDFLLIATDILDSNSTGFAVGADRDKIASAFNEQ
                     FDKDARLALPGVVSRKKQVVPPMQSMFEG"
ORIGIN
        1 gattgcccga aaaatcagta gtttgcgaag cttttaccgt tatttgacac gaattgatgt
       61 cgtcaaacgc aacccatttg agctggttga attaaaaaag cagcatcatc atttacctca
      121 atttttctat gaagccgaga ttcaggaact gttcaagaca gttgctggca aaaccccgct
      181 ggatcaacgt aatcgcgctt tgttggaagt tttgtatggc accggtattc gagtttccga
      241 gtgtgccaag ctgacattga atcaggtcga tttcaatacg gcattactgt tgattcatgg
      301 taaaggcaac aaagataggt atgtgccctt tggacagtac gcccagcaag cactacgaac
      361 ctatttaaaa gatggtcgac aagttttgat ggctaaaagt caggcacagc atcgatatgt
      421 atttgtgaac cagtatgggc gtccgattac ctcgcgtggc attgaatata ttttggatca
      481 gctcatcaag cagacgacgc tgacagctaa cattcatccc cacatgctgc ggcatagttt
      541 tgcaacccat atgctggatc atggtgctga cctgcgaact gttcaagagc tactgggtca
      601 tgcaagttta tcaaccacac aaatctacac gcatgtcacc atggcacatt taaaaaatga
      661 gtatatgaaa tattatccga aacataatta agactaaagc atgatgcaaa agcagtctga
      721 gttttttaag ctaagaacat tggcgataac agattaatcg ctactttagc tgtttttatc
      781 cgacgagata cgcagatcac gcgctcgcag tcgcagaaac ctacacataa tgacctggaa
      841 gcctaaatag ccaaaattca gccatttagg cttccggccc acttatgctc cggtttctaa
      901 gcgcttctgc tcgcgctcac ttaaaaagga gcatgactat gacaacaatt gcagcagtaa
      961 gaaaagatgg tgtgaccgct ttggccggtg acggtcaggt aacccttggc gaaaaggtca
     1021 tcatgaaagg caacgcgcag aaagttcgcc ggatctatca tgatcaagtc gtcatcgggt
     1081 ttgccggcgg ggtggcagat gctttcaccc tgcaagactg gtttgaaaag aagctggagc
     1141 attatgcggg caacttgcga cgttccgcag ttgcgctggc tcaagattgg cgcaaggatc
     1201 cgaccttgca gaaacttgag gccatgatga tcgtgatgga tgagcatgac ctgttactcg
     1261 tatccggatc tggcgaagtg atagatccag atgaagacgt ggtagcgatc ggctccggcg
     1321 gcaactttgc gcaagccgcg gcaatcgcga tgctgcggca tgccccagat atgacaccag
     1381 ctgacattgc caaagaagca gtgaatatcg caggaaatat cgatattttc acaaaccaca
     1441 atgttattgt cgaaagcttt tagtttgtaa ccgtcggcaa ttacattgac ctacaggagg
     1501 cttatgatgg cagaagtaca aaccccaaaa cagatcgttg aaaaactcga tcaatatgtc
     1561 attggacaaa atgatgcaaa acgggccgtc gcggttgcct tgtataaccg ttatcggcga
     1621 atgcaattat cgccaaaaat gcaagaagag attaccccga aaaacttact gatgatcgga
     1681 ccaaccggtg tcgggaaaac cgaaattgca cgacgactgg cgaaaatagt tgaggcgcca
     1741 tttgtgaagg tggaagcgac taagtttacg gaagttggct acgttggccg tgacgtcgaa
     1801 tccatggtcc gagatcttgc cgaaactgcc gttgccatgg aagaagagaa gcaattttca
     1861 aaggttcgca tacgtgccga aaaagaagcc aataagcgtt tggttaaaat tttagtgccg
     1921 gccattcgta aggaaaagaa taccaatccg atggccgaga tgatgagcat gttgcaagga
     1981 atgcaaaatg gcaaaatgcc agctggcgat gatgcagacg caggcggcga agtgaccgat
     2041 gatattcgca ataagcgttt aagcgtggca gagcaactgg aaaaaggatt acttgaagat
     2101 catgaaatca ccgttgctgt caatgatgag aaaaaaggcg gtggcatggg tgacatgtac
     2161 ggtcagatgg gcattgatct aagcgacacc attggcgctt taatgcctaa gaaaaaggtt
     2221 gagcggacca tgaccgtcaa agaagctcgc gaaatcttca tcaaagagga atctgacaaa
     2281 ctggtcaatc atgccgacat ttatcacgac gccattcaaa gtgccgagaa taacgggatc
     2341 attttcatcg acgaaatcga taaaattgct gcgggaaaca agcataatag cggcgaagtt
     2401 tcgcgtgaag gtgtgcagcg agatatttta ccgattgtag aaggatcgca gattaacact
     2461 aagtatggtc ctatcaatac ggatcacatc ttgttcattg gctcaggtgc gtttgccgag
     2521 gctaagccta gtgatttgat tgctgaactt caagggcgtt ttccaattcg ggttgaattg
     2581 aaggacttaa ccgaaaaaga ctttgtgcgg atcttgaccg agccagacaa tgctttgatc
     2641 aagcagtata tcgccttgat tggtgcagat ggcgtgaaga tcaccttcac gaaggaagcg
     2701 gttgatcgaa ttgcagagat tgcgactcag gttaaccacg acactgataa tattggggca
     2761 cggcgactgg cgaccattct tgaaaaactg cttgaagacg tactttatga aggtccagat
     2821 atggcgatgg gcgctgtgac cgtcacccag caatatgtgg atgacaagat tggccatatt
     2881 gcggctgatt caaacatgac gcggtatatt ttgtagttaa caataatgtt gtaggtaaag
     2941 gatgaggatg tatggtaacg attgcaaatg actttttgac agttaaaatc agtcggcatg
     3001 gtgctgaact gaccagtatc aaagataacc tgacaggcag ggagcgtctg tggcaagcag
     3061 atcctgcggt gtggggtcgc cacgccccgg tcttgttccc gattgttggg gcgctggctg
     3121 acaatcaata tcattacgca ggcaagactt accacatggg ccagcacggt tttgcccgtg
     3181 atcgtgattt cacggtgctc tctgcgacac cgtttaaagc gagcttcgtt ctgaaggatg
     3241 atgacaaaac gcgggcgatg tacccgttcg cttttcgttt aatcatcacg tttgcactag
     3301 aaaataacaa tctacatgtc acgtatcacg ttgacaatcc ggacaaaagt gagccactgt
     3361 tctttagcat cggcggccat ccgggcttca aggtcccaat gacgccggat actcaattct
     3421 ccgattatta tttgaacttc aaaccgcgta agtcgcttgt tcagattcca ttggttgctg
     3481 gtgaaggcat tgattacacg caccggacct tggctgcaac tgatgccaat ttggccttaa
     3541 cgcacgaaac atttgatcat gatgctttaa ttttcgcgtt gcttggtaag acaaccttca
     3601 acttggtttc tgacaagacg aaacatggtg tcagcgttac catgaccgat accccatatc
     3661 tgggcgtttg gagtccgtat ccaaccactg gcgactttgt ctgcatcgaa ccttggtggg
     3721 gcatcgccga cacgattggc agcactggcg acctgacgcg caaacttggg atcaatcgac
     3781 ttgaacctgg cacggcattt gagaagggtt acatgatcag cattttctaa ggtgtcatca
     3841 gtttgtcgat taggtacacg aaaaaaagac atccagtttc ggatgtcttt ttggttacca
     3901 tcaaaaggtg actaggagcg gccccggtgt tgacgaagat attggcctaa gccaaagggc
     3961 accatatttt catctccggc cttgatgcgt ttgaagtttg cccgatgttt gatcaaaaag
     4021 acaaccagca gcccgcaggc aacagttgtc agcaaccaat catggtaaac aagcgaccaa
     4081 gctgtgatca acaccatacc cagtgtgctg gcaacgctga ccatggacgt tagcaagatc
     4141 aaactaaacc agatggcaaa tgcaatgaca aaaaatggcg gattatatgc aagtaaaatg
     4201 ccagcgctag ttgccaccgc cttaccgcct ttaaagcgaa tgtagatcga aaatgtatga
     4261 ccgaatacgg ccgctaaacc cacgatcagc accagccaat gatgctcgat gccaaagaga
     4321 atgggtaagc tggcagccaa cgtgcctttt aagatatcca gcaccaagac aattgagccg
     4381 ccgactggcc ctaacatgcg ataagcattt gtggtgccaa tattgtgact cccgcctttg
     4441 cggatatcgg tgtgataaaa aagtttacca atgaccacac caaacgggat ggcgcctatg
     4501 aaatacgcga gtataaaaca aagcacaagt atcaaatgtg cccctcctct caaactagaa
     4561 actattttag catttttgac ttttgagtga tacgtcagta gaataaaacg aacgtacatt
     4621 cgaataaaac ctgtgaagcg ggttgtggcg cgatttggtg ccgtcttgtg caaggatcat
     4681 ggcggggcac agcgtagata tggtgccagc gggcgatgaa tttcacgtca agaagtcata
     4741 gttatgtgcc atgcttaggg aaatgcggtt ttctgctgag ctttgggaca ttgacacggc
     4801 taataaaatt taaatgaaca atgatggtat tagccaactg ggtcgatttt gaggagaaaa
     4861 caggagtcct gagagcaata tggtgaggtc tgctgttgat ggtgttgatg cctaaacgcg
     4921 ctcgcagcaa cctgcgtgta aggaccttgg gtgcaatggt caaagtccaa ccatcgcacc
     4981 caaggccgct tatgctccgg tttctaatcg ggctgctcta ttgaaacgcg ctcgcagtcg
     5041 cagcaacctg cgtgtaagga ccttggtcgc aatggtcaaa acccaaccat cacgtccaag
     5101 gccgcttaca ttccggttgc taaccgctcc tgctcgcgct ctactgaaac gcgctcgcca
     5161 gcccagaaac ctgcacataa ggaccttggg cacaatggtc aaaacccgac catcgcaccc
     5221 aaggccgctt atgctccggt ttctaaccgg gctgactcgc gctcttattt tttatttctg
     5281 aaatctcaac gcgtggtgta ttctataact tagttgttca aaaaagggag tttactatgg
     5341 ataaagcaac gcaagcatat aatgattcat ccattcaggt gctgcatggc ttggaagctg
     5401 tgcggaagcg tccggggatg tatattggtt ccaccgatgg ccgcggtttg catcacttgg
     5461 tctatgaaat cgtggacaac tctgtcgatg aagcgctcgc ggggtttggg gatgagatca
     5521 atgtgacgat tcacgccgat aactctgtga ccgtacagga tcatggtcgc gggatgccaa
     5581 cggggatgca cccgagtggc aaaccgacga ttgaagtcat tttaaccgtg ctacatgccg
     5641 gcggaaagtt taaccaaaat agttacaaaa cttctggtgg tttgcatggg gttggctcaa
     5701 gcgtcgtcaa tgccttatcg gagtcattga ctgtgcgagt tgtgcgggat aagcacgcat
     5761 ttgaggagca ttttatcaat ggcggtcatc ctgatggcag tttgcagaag ttgggcaaag
     5821 ttaatgaacc taatggcacg accatcacgt tcaagccgga cccgactatt tttcaaacca
     5881 ccgtcttcag ttatgatacc ttggccgaac gcttgcgcga atcagccttt ctactgaaaa
     5941 atattacgat taatctgacg gatgaacgca ccggcaagca tgacagttat cactatcctg
     6001 atggcttggt cagttttgtt aaatacctta atgaaggcaa agacgcattg tcacaggtga
     6061 tcaattttga aggcaaaaag gacggtatcg tggttgattt tgccggccaa tataacgatg
     6121 gctattctga aaacctgatt tcgtttgtta ataacgttcg cactggtgat ggcgggacgc
     6181 atgaaattgg cttgcgcagc ggcatgacgc gagcattcaa tgagtttgcc cgaaaagtcg
     6241 gcttgctgaa ggaacgcgac aagaaccttg aaggcagtga tgtgcgtgaa ggttttgcag
     6301 gtattttaag tgtccgcatt ccagaagaaa ttttgcaatt tgagggccag acaaagggta
     6361 agcttggtac gccgcaagcc cgcactgtgg tcgatgggat tgtctatgac aagctgtcaa
     6421 cttttttgat ggaaaacggt gaagagtcgc aagagttggt tcgtaaagcc gtcaaagccc
     6481 gtgatgcgcg ggaagcggct cgaaaagcgc gcgacgatag ccggacggga cgcaagcgca
     6541 agaaggacca aggtttgctt tccggtaaat tgaccccggc gcaaaccaag aaccctaagc
     6601 gtaacgaatt gtatctcgtc gaaggggatt ctgccggtgg ttcagctaaa caaggccgag
     6661 accgtaagtt tcaggcgatc ttgccattgc gagggaaagt actgaatacc cagaaggcca
     6721 agttacagga catcgttaaa aacgaagaaa tcaatacgat gatttacacc atcggcgctg
     6781 gtgtcggtgc ggattttgat ctgcagcagg ccaactacga caaaatcatt attatgactg
     6841 atgcggatac tgatggcgcg catattcaga ttttgctact aaccttcttt tatcgctaca
     6901 tgcggccgct gattgacgca ggccgaattt acattgcttt gccaccattg tatcggctgc
     6961 aaaaaggcgc cggtgccaaa accaagatca gttatgcttg gaccgatgaa gagttggcca
     7021 aagagaccaa ggccatgggc aagggttaca cattgacccg atttaaagga cttggggaaa
     7081 tgaatgccga ccagctttgg gaaacgacca tgaatcctga gacgcggact ttgatccggg
     7141 ttcggattga cgatgctcag ctggcggagc gacgcgtgac cactttgatg ggtgatcgcg
     7201 ttgagccgcg tcgtgaatgg attgagcata acgtcaagtt tgatatggat gacgacggca
     7261 gtattttgga aaccccgact gctaatcacg aaaaattaca gtttggtgcc aagcaaatcg
     7321 tcaaacaact ggacaagaaa ggaaagtaaa agccattggc caatcagatt caagaactga
     7381 ccttagaaga ggtcatgggc gaccggtttg gccggtactc gaaatacatt attcaagaac
     7441 gggcgctgcc tgatgtgcgt gacggcctta aaccggttca gcgtcgcatt ttatttgcga
     7501 tgaaccaaga tggcaatacg tatgataagg gcttccgcaa gtcggctaaa agtgtcggga
     7561 atgtcatggg taattatcat ccccacggcg acagctccat ttatgaagcg atggttcggc
     7621 tgagccaaga ttggaagtta cgggccccac tgattcagat gcacgggaat aacggttcca
     7681 tggatggtga tccgccagct gcaatgcgat acacggaagc gcgtttaagc aaaatcagca
     7741 aggaaatgct ggccgatatc gataaggaaa ccgtcgatat ggtgttgaac tttgatgaca
     7801 cggcacagga gccaactgtg ttgcccgcag gatttccgaa tttgctggtg aatggtgcaa
     7861 cgggcatctc tgcaggttac gcgaccgaaa ttccgccgca taacttgcgc gaagtgatca
     7921 atgcggtctt atatttgctg aagcatccca ctgctgattt agatacttta atgcaatacg
     7981 tcaagggtcc cgattttcca acaggtggga ttattcaagg gcttgatggt atcaagcaag
     8041 cttacgaaac cggccgcggt aaaatcgtgg ttcgttctcg gacacacatc gaaaccattc
     8101 gtggcggtcg tgagaagatc gtggtcaccg agatcccgta tgatgtcaat aaagcgcaga
     8161 tgattaaaaa aatcgatgaa ttacgcatca acaaaaaagt ggacggtatc gccgaagtcc
     8221 gtgacgaaag cgaccgtttt gggcttagcg ttgtcatcga attaaaaaaa gaagccgatg
     8281 cacatggcat cttaaactat ttatttaaaa ataccgatct gcaaattgca tacaacttta
     8341 acatggtcgc tattgccgac atgcagccga agttactagg actcaaggcc atgttggaag
     8401 catacgtcga acatcgacgc gatgtggtca ctcggcgaac gcgttttgac ctcaacaagg
     8461 ccgctgctcg acagcacatt gtcgaaggct tgatcaaaat gctatcgatt ttggatcagg
     8521 tcatcgccgc gattcgtgct tccaaggata aaggagatgc taagcgtaac ttagtcaaga
     8581 agtttgactt ttcggaagct caggcggaag cgattgtttc cttgcagctg tatcgattga
     8641 ccaataccga tatcacggct ttacagaaag aagcagcaca attggcgaaa gcaatcgccg
     8701 agtatcaaga tattttggcc cgccccgctg cccgcgatcg ggtgattgaa ggcgagttga
     8761 agcggattgc caaggagtac ggggatgatc gtcgcagcag cattcaagcc aaaattgaaa
     8821 cgcttgaagt ggcgacaacg gtgacggtgg ctgatgaaac cgtcatggtg caggtttctc
     8881 gtgatggcta cgttaaacgc agttcactgc gcagttatca ggcggttgat ccggccgaca
     8941 atggtttgaa ggccaatgat cttgctattt tcactggcga actgagtacg ttgcagcatc
     9001 tttacatcgt gacaaatgcc ggaaatgtca tttatcgacc agtgcatgaa attagtgatg
     9061 cgcgttggaa agacaccggc gaacacttaa gccaaacagt tggccttggc actgacgaaa
     9121 aagtcttggc agtgtttgct tttgatcaac tcgatggcgc tggcagtttt gtgttagggt
     9181 caagtgatgg gtacatcaaa caaactgcct taagtgattt gcagccgcaa cggacgtaca
     9241 agagtaagcc gatgatggcg atgaagctga aagacccagc cgcgattgtc accaatgcat
     9301 acttcacgac tgatcagcaa caggatgtct ttgtggtcag ccgccacgct tacggactga
     9361 cattcccgtt aagcgatgtg tcaactgtcg gtgcccgggc aaccggcgtt aaaagtatgg
     9421 atctaaagcc agacgatgag gttgtcaatt tcattctagt gaaggatcca actacggcta
     9481 aggtcggtat tttgacccaa cgtggcgcct tcaaaaagat ggccttaagc gaagtcgggg
     9541 aaatgagtcg tgcccgtcgt ggtttactgg tcttgcgtga gcttaagcgt gatccgcatc
     9601 ggattgtcgc gatgatgtca gtcgatgacg ctacccgcct gaatgttttg accgatacgg
     9661 gtaaggtaac gacccttaat ccggcacaac atccagcagg tgaccgctat tcgaatggtt
     9721 cgtttgtcat tgacactgat gtccttggca agccagtttt tgttcaaacc aaagaagaac
     9781 cagcagatca agtcgaataa atggtgatca ttgacgccgc cgtctgtact aatacagatg
     9841 gcggcgtttt tgattattat aggacagatc agttgtgcac aatttaacaa aatgacgaaa
     9901 tcatgggcga aaagaagcga cgaagcacac ttaaaaaaca atataacgcc tattatatgg
     9961 gcaataaaac gcttgcatag atttggcggc gtgttatact gtgtttgtaa gaactgtcac
    10021 atctgtaatc cactttagga ggcaaacaac tatgaaacag cttgacgaaa ccaaagttcc
    10081 taattattgg gaaggcttta acggcggcga ctggcaagaa gaaattaatg tgcgcgattt
    10141 tatcgagcat aacctgaacc aatatgacgg ggacgaaagt ttccttgctg gccccactga
    10201 agcgacaaca gtcctgaaca atcaggttct aaatttaaag aaacaagaac gtgcaaatgg
    10261 cggtgttttg gatgctgaca acaatattcc atctacgatc acctcacacg gacctggtta
    10321 tttgaacaaa gatcttgaaa agattgttgg tgttcagacc gacaagccat tcaaacgagc
    10381 attcatgcca tttggcggta ttcgaatggc tgaagatgca ttggaatctt atggcttcaa
    10441 gacagatcct caagaacaca agattttcaa tgaatatcgt aagacccata accaaggtgt
    10501 ctttgatgct tatactcctg atatgcgaaa ggctcgccat tacaagatcg tgactggctt
    10561 gccagacgca tacggccgtg gccggattgt ttctgatttc ccacggatcg ctgtttacgg
    10621 gatcgatcgt ttgatggccg agaagttcaa ggattataac ttgactggcg acggcgaaat
    10681 gactgacgat gtgatcaaac tgcgtgaaga aatcaatgaa caatatcgtg ccttaaacga
    10741 catgaagaag atggccaagg aatatggcta tgacatctcg cgtccggcag ctaatgcgca
    10801 agaagctgtt cagtggatct actttggcta tctggctgct gttaagacgc aaaacggtgc
    10861 cgcaatgtcc gttggccgga tcgatacggt tattgatgct tatatccaac gcgatatgcg
    10921 cttaggcaaa ttgaacgaag aacaggcaca ggaactgatt gatcatttgg ttatgaaatt
    10981 gcggatggtt cgtttcatcc ggactgaaga atataactca ctgttctcag gcgatccaat
    11041 ctgggcaacc ttgtcattgg caggaatggg caatgatggc cgtcaccacg ttaccaagac
    11101 ggctttccgt ttcctgaaga ctttggacaa catgggcgca gcaccagaac caaacatcac
    11161 cttgctttgg agcgaacgct tgccagaagg cttcaaacgc tatgcaaccg aagtatccat
    11221 ccaaagttca accattcaat atgaaaatga tgatctgatg cgcaacgaat ggggtaccga
    11281 ttactacggt attgcttgct gtgtctcggc acaaccaatt gctgatggcg ttcaatactt
    11341 tggtgcccgt gctaacttag ctaagacagt tctgtatgcg atcaacggtg ggaaagatga
    11401 aattcaggaa gcgcaagtag ggcctgaata tgcaccgatc accagcgatt acattgatta
    11461 caaagaattc atgaataagt tcgacaagat gatggactgg ctggccgaca cgtatgtcaa
    11521 tgctttgaat gtgattcact atatgcatga caagtattat tatgaagctg cacagctggc
    11581 attgaaggat acccaactga accggacctt cgcaaccggg atttccggcc tgtcacacgc
    11641 agttgattcc atcagtgcaa tcaagtatgg tcatgtcaag gcaattcgcg atgaaaacgg
    11701 tgttgcagtt gacttcgttg ctgacaatga tgactatcca cgctatggta acaacgatga
    11761 tcgcgctgat gacatcgcta agtggttggt taagaccttc tataacaaga tgaacacgca
    11821 tcatctgtat cgcggcgcga agttgagtac cagtgtcctg accattactt ccaacgtggt
    11881 ttatggtaag aatacaggga caacaccaaa cggtcgtcaa aaaggcgaac cattctcacc
    11941 aggtgccaac ccggcatacg gcgcagaaaa gaacggcgca ttggcatccc tgatgtccac
    12001 cgccaagatt ccgtatcatt acgcaactga cggcattagt aatacgtttg gggttactcc
    12061 gaacacactg ggccacgatg atgaaactcg taaggatacc ttggttcaca tggttgacgg
    12121 ctatatggaa aacagcggca tgcatttgaa catcaacgtc ttcaacaagg agaccctgat
    12181 tgatgctcag aagcacccag aagaataccc aacattgacc gttcgggttt ctggctactg
    12241 cgtctacttc gcagatttga ccaaggaaca acaagacgat gtcattgctc ggaccttctt
    12301 cgaagaaatg taagcagctt aactcaagac aggaagtcat tcctgttttg ccaaaagacg
    12361 gcaacgatgc tgttgccgtt ttttggcaga atgaaatgaa aatcaattga aaacgacaca
    12421 tgatgttgta gtggaggcaa taagatgaaa ctcatcgatc agtcacaaag cccattaaat
    12481 atcttagaac aagttggtca ggatcatgat ggcccgatca aagggtatgt tcactcggtc
    12541 gaaagttttg gttcggtcga tggccctggt attcgcttcg ttgtctttat gcaagggtgt
    12601 cgcatgcgtt gccagtattg tcacaaccct gacacctgga acattggggt tggtgaagaa
    12661 atgacggccg atcaaatttt ggcggatgcc cagcgctata aagctttctg gggtgaccaa
    12721 gggggtatta cctgcagtgg cggtgagagt ttggtacaaa tcgatttcat tctcgaactc
    12781 ttcaccaagg ctaaggcact gggaatttcg acttgcctcg atacgtcagg cggccccttc
    12841 acgcgtgacc aaccgtggtt tggccagttt gaaaagctga tggctgttac tgacatctca
    12901 ttagttgata taaaacacat tgattcggcc gagcataaaa agctcaccgg ttttcctaat
    12961 gaaaatattt tggatatggt gcagtatatg tcggcgcatg gtgatgacat gtggattcgc
    13021 cacgttctgg tcccggaacg cactgacttt gacccttatc tcaaacggtt aggggactat
    13081 attgcgacat tggacaaaaa cgtggtccaa aaagttgaga ttctgccgta tcacacgtta
    13141 ggcgttaaaa agtatcacga gcttggcatt acgtacccgc ttgaaggcat cgaaccgccg
    13201 tctgccgatc gcgttaagaa tgcagagaat ctgctgcacg ttaaggatta taccggatgg
    13261 caaagctggc gtccgaaacc agttgcgagc aactgaattt ttagctagaa cttaacgtaa
    13321 cgattaaaaa cgcggcaaat tcgttgcgtt ttttttcatt gccacttatg atgatggttg
    13381 aacgatatta ttaaattata aacgaaaggg aagccgccct atgaaaacga aacaagagcg
    13441 cattttttcc tcaaagacac taacttattt tctgcaattg gcagaaacca tgaactacac
    13501 ccaagccgcg caattgcttg gcattaccca gccagcctta acacagcaga tcaagaaatt
    13561 ggaacggacg gtgggggcac cgctgtttta ttctgtcggg aagaaactgc atttatctga
    13621 cgctggtcag accatgttaa agtcaaccca tgaaatctac gagatcttga accagacaac
    13681 cgacgaaatt caacaaacaa ccagtgcaac cgtcggaaaa atcaatattg ggttattaag
    13741 ctcaatcgag gatagcgcct ttattgcgtt cattgctcat tactatcaac tgaatcctga
    13801 agttgaagta acgctgcgga tgatgacccg tcacgaaatt tgggaatcat tggaaaacaa
    13861 ccagattgat ttggctatca tgaatctgcc agatgaaacc attaagaact ggaaaccata
    13921 cgccagcaag aaaattattg atgaacaatt gctgttcttg caccacgatg acgccttggc
    13981 taaccgtaag cgaatccatt tcaaagatac tttagctgaa ccttgggcaa cttatcctga
    14041 cgactatttc cttggacaac ttctgcgtga ggcgtacaag aatcaaatgg ttgatttccc
    14101 gcacgtggtc gcacatttca ccacgccgta tcagttaacc caattcgtta acttgtcagg
    14161 ggtcaacacg gccttaccaa ccagttttgt tcgggcacgc gctgatcaaa tcaaggccta
    14221 tgctattgcg tttgatccgg ccattcgctt tgagatttct tttgtttatc gcaaagagaa
    14281 agctgacatt ccgcggatct cgaacttctt ccagaccttt gacgattatc tgaaggaaaa
    14341 agattacttg tcgcgggtca gtgaaaaccg tgttaaactt gataagtaaa ttattcagtt
    14401 gaggagcgat cagataagat gacgactttg atttttgggc atcagaaccc ggacaccgac
    14461 gcgattacga gtgccatgag ctgggcagaa tttcagaaac aggcaggcaa cacggatgtt
    14521 gaggcggtag cattaggcga accgaacgat gaaactaagt tcgtccttga tcacttcaag
    14581 gttcaggcac cgcgggttat caagacggca gccaacgaga cggatcatgt catgttggtt
    14641 gatcacaacg aatttcaaca aagtgtcagt gatatcgaag acgtgacgat tgattctgtt
    14701 gtcgaccatc atcgcatcgc taactttcac acggcagcgc cgctgtttta ccgagcagaa
    14761 ccggttggca gcaccaatac cgtcattttt gagatgttcc aagaatatgg cttcaaaatt
    14821 tcgccaacat tggctggttt gatggcttct ggtttgattt cagacacgct gttgttgaag
    14881 tcgccgaccg caaccgacaa ggataagaag attttgccag aaatggcgaa gattgccgga
    14941 attgatttgc agtcatatgg tcttgccatg ctgaaggcag gtactaattt ggccgccaag
    15001 tcagatatgg acattatcga aggcgatgct aagagtttca ccatgggcgg caagtctatt
    15061 cgcatcggac aggtcaatac cgtcgatctg aacgacattt acgcacgtca ggacgaattg
    15121 atcaatgcca tgaccaaaga ggcgcaggcg aaaggctacg atgatttcct gctgattgcc
    15181 actgacatct tggacagcaa ttcaactggt ttcgcagtcg gtgctgaccg cgataaaatc
    15241 gccagtgctt tcaacgaaca gttcgacaag gacgcgcgtt tggcattgcc tggggttgtt
    15301 tctcgcaaaa agcaggtcgt tccgccaatg cagagcatgt ttgaaggtta actttcatct
    15361 ttaattgcac acaattgttt tattgttcta aggaaagtcg cagctagcta gttgcggctt
    15421 ttttgtggct ctacgtcaac tggtgttgaa gaataaatt
//
