LOCUS       gnlProkkaHFNBABML_24   17054 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HFNBABML_24.
ACCESSION   gnlProkkaHFNBABML_24
VERSION     gnlProkkaHFNBABML_24
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 04:31:52
            Original ID  :: gnl|Prokka|HFNBABML_24
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17054
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17054
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4629:7054]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4630..7054
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..17054
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17054
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             178..291
                     /locus_tag="ctg18_1"
                     /transl_table=11
                     /translation="MPTKIWLKPEQLDLYIKHLERFRDLYSKLDCSGIVNL"
     CDS             520..621
                     /locus_tag="ctg18_2"
                     /transl_table=11
                     /translation="MEEVRKLRQEKAELEKENDFLKKAAAFFAKEID"
     CDS             791..1060
                     /locus_tag="ctg18_3"
                     /transl_table=11
                     /translation="MQWKEVNQFFETESIKLSDIEPSKVSYREVQRNQINTTIYNEKGN
                     IKDIDTSIIRDMYDKSKPTLKQGAYISAIAASLEGGYCIYNSNN"
     CDS             1220..1519
                     /locus_tag="ctg18_4"
                     /transl_table=11
                     /translation="MCTASFGIAKEAYKFRKNLITKEEFLLNSQILCVEVSVSALSSIL
                     GHAVIPIPILGSVIGNNIGTFLYEIAKDNLTMKEKLLIADYFKEIQEYNYFLDN"
     CDS             complement(1619..2530)
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 99; E-value: 4.5e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg18_5"
                     /transl_table=11
                     /translation="MIDSKEINKFAFPLVLTNIGQVIIGQIALHFAVNNSSIALSGISI
                     IQNLLFAFGGLLGAFSLSFNIKSSKAYSNRQTNRFDDLLKSNLTLDLIIGVAFAVFVII
                     FGNVILKQLYGFKGQLLSLSTIYLVFMSPYIGLTLLNFSLTNLLRVQKKTKPIMWVGLI
                     SSLIDVVLNYVLVPQIGIKGAAISTIVSLAFISLSYLFMVYPMILKALSITSTTKFELI
                     TFGIPLVGQEILESVLFIMVFDALMSRLGVELLAIYAVISQLLSIVSVPSFVYSTTVSI
                     YLPEAEKIGEVNVFLKNIFKNS"
     CDS             complement(2760..2849)
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MKEHFVIRGKRDFIVNKVADEYIGYDLLD"
     CDS             complement(2846..3448)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_7"
                     /sec_met_domain="TIGR04085 (E-value: 1.1e-15, bitscore:
                     49.8, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 3.5e-13, bitscore: 41.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGIEYMSVMVICPTGRANDGSILADKKQWYPVFLDLTERISKGE
                     FKVKFKIVPPNESDVFLTHYFPLAFYNRSDLLENVWHQKVDINFDKPREISCQAGVRAC
                     SINHKGDVYGCDLMNGIDELVAGNVKEQKFSEIWHHSAVFNKLRSITFDDISGKCSECP
                     LPWCGGGCRCSALELDGTLLGSDLACFYEQKGGGVVV"
     CDS             complement(3542..4633)
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="MSKKIFNLYGMNMFLSGLPYYFVGILLLKHLGFSFTEIATLSVIT
                     ELCGSVFDIPLSYISSKIGYKKILAISNLLLILALWGLLFGKSNIIYISAIFFGLSESL
                     SSGVLISYNFEIIDDEVVYKSFLKNLNTLKYIFIAIITIISPPLLHRNYIYPIIISIVF
                     VIFSLLYLIGLPEIKKEQNNKQKFFSLDNIQNIPWLLIILGVAFSTLIMISNSYAGIFL
                     NEQGLSLDMLGIILFMFNISMALGSYLKIKFEVSLMLPVLAILMFFQTNLIIQIIILLL
                     MRVLNSNYNNHFYYKFNMSIEKNRAVSWSVYNLFISISFMLADFLAGIFADNFSIRSNY
                     LIFGIVALCCLVSYSFSNREKRT"
     CDS             complement(4630..5949)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_9"
                     /sec_met_domain="Streptide_RRE (E-value: 1e-24, bitscore:
                     79.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5e-20, bitscore: 64.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.8e-07, bitscore: 22.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.4e-13, bitscore:
                     43.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTISEDFLFRLEKFGGILINKVTFDRIELDESEAYFLYLVQNHG
                     FEIATSFFKKEIKAGKLERVLLLNIYSDNNIEGSSKNPDETLQNARKHVAKLKKHNILS
                     FPLELVIYPSMYCDLKCGFCFLANREDRNAKPAKDWERILRQAKDNGVLSVSILGGEPT
                     RYFDIDNLLIACEELKIKTTITTNAQLIKKSTVEILAKSKYITPVLSLQTLDPKLNFEL
                     MGVRPDRQIKLAKYFKEVGKKCRINAVYTKQSYEQIIELVDFCIENKIDRFSVANYSEV
                     TGYTKIKKKYDLADLRRLNEYVTDYITQREANLNFATEGCHLFTAYPELINNSIEFSEF
                     GEMYYGCRAKYTKMEIMSNGDILPCIAFLGVNQTKQNAFEKDLLDVWYDDPLYGGIRSF
                     RTKNSKCLSCGLLKICEGGCYVNLIKEKSPKYFRDPVCNL"
     CDS             complement(6019..6111)
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="MSKELEKVLESSSMAKGDGWKVMAKGDGWE"
     CDS             complement(6194..7054)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_11"
                     /sec_met_domain="TIGR01716 (E-value: 5.1e-51, bitscore:
                     165.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFGEIFKKFRESRGLRLKDVAKAGISTSQLSRFEKGETDLTIS
                     KFMFILDEINMPIDEFMYAVHDFHRDELNELLSKVRHFVSTRDVEGMKKLLYSQMELED
                     RREKFHQINIILLKIRLQDLSGETYYTKDDLTYLTDYLFSVEYWGYYELLIFSNTLDVL
                     NHDVFMVLAREMFRRSDFYKEIPNNRRLISTMLLNGYITCVEREKFMDALYFEKQLNQC
                     FFIETEVYERLVFKYAQNLYQYKEDGNVKAIIEMKKCVGAMKLAGSHHLAKTYEGHLEK
                     ILASS"
     CDS             complement(7294..8106)
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 266.8; E-value: 2.9e-81)"
                     /gene_kind="other"
                     /locus_tag="ctg18_12"
                     /transl_table=11
                     /translation="MLLKIIKLARSTYYYHLKQLDQNDKDYDIKAEIQAIFTEHKGNYG
                     YRRMTLELRNRGIVINHKRVQRLMKVLGLTARIRRKRKYSSYQGEVGMKAENLIQRQFE
                     ASKPLEKCYTDVTEFAIPASSQKLYLSPILDGFNSEIIAYNLSKSPNLIQVKAMLEQAF
                     TEKHYKNTILHSDQGWQYQHDFYHHFLEEKGIQPSMSRKGNSPDNGMMESFFGILKSEM
                     FYGYEKTFKSIEHLEQAIADYINYYNNKRIKVKLKGLSPVQYRTKSFT"
     CDS             complement(8124..8690)
                     /locus_tag="ctg18_13"
                     /transl_table=11
                     /translation="MNCTPKVRQKKSNFRGVFIMKLTYEDKVQIYELRNQGYSLDQLSN
                     KFGINISNLSYMIKLIDRYGIEIAKKGKNRYYSPELKQEMIDKVLYKGYSQDRVSLEYA
                     LPNRGTLPNWLAHYKKNGYTIVEKTRGRLSKMGRKPKKKLEEMERLQAENEYLRAENAV
                     LKKLRELRLREEKEQEEKRKLSEDW"
     CDS             complement(8869..9027)
                     /locus_tag="ctg18_14"
                     /transl_table=11
                     /translation="MTKHSYVAKFKRKDETVFTKRFLASDLFEAVEHALEYATKRDILY
                     LDLGHAG"
     CDS             complement(9039..9170)
                     /locus_tag="ctg18_15"
                     /transl_table=11
                     /translation="MNIEECKQISILDVANRLGISFKQVYDKAVYWIYSGVKGQYEY"
     CDS             complement(9180..9692)
                     /locus_tag="ctg18_16"
                     /transl_table=11
                     /translation="MAAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQ
                     PYMTESAYSQELTSQNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSD
                     LKNANQSKTNQTETRTVNLNYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSVPS
                     LPNTTTK"
     CDS             complement(10092..13271)
                     /gene_functions="other (smcogs) SMCOG1218:Exonuclease
                     (Score: 498.4; E-value: 7.8e-151)"
                     /gene_kind="other"
                     /locus_tag="ctg18_17"
                     /transl_table=11
                     /translation="MRPVQLELTNFGPYRKEVINFTQFDHAPLFLIGGDTGAGKSTLFD
                     AMTVALFATTSGDRNVEEMRSTFAGPEDDLTKVTFYFQQGNHLYRIDRVLQQERAKQGG
                     GTTMQKATASLVIVDKIGGQEIEKLGDKIKEVSDQIEQILGLNAEQFKQIILLPQNDFS
                     RFLKEDSKTKTQILKKIFGTGIFDHFQKSLEERLRQSNKDMEKRQAQLDGHFASQVWSE
                     EELSVLEQTPASEKLTRLEEFLSQRQENVTKQKSILKAAHEDLAQLQKSLQTAQDLAKI
                     FQELEQAKERYRLEIEEGAQGQAEAKVHLEELQFAQGLQETIRTLKQYRKQLMQLEQDL
                     EIAQEALSEKQQAFEDVKAKKEELTVQSKDFLQKEEELETWKENIIYAQSLAQEQEKIK
                     RSTTNYKQLEETYQQARKEVEMLNKSLSDLEANRLSLDSLHEAEKLFQIVGYSVENQLA
                     QDLKEIENLNQELTKTEKRHQTLSFDIDQAQEILKELEEELRRTLVSRRQLIIVQLQAE
                     LEEGHPCMVCGALEHPNVGGAQADEVALKNLMDQVEKLQAQKEKQVATLSNRQATLSEV
                     ASKRQDLLDQVAKVKATLEKHYQELEEHVKGRFDFDFSIDYETDRGQALLLKVEQYYQE
                     LQKRYDKEETDYIRYQDELGKAQKKATDLAKTYQEAKAVLDQAQERLEDLQEAHPELES
                     VEVYQERISLAHQELNLYNKQVKENSEAYNQLHADIKGIKGQIESITKSKDKVNQDVKR
                     LSAELEQSLKAEGALANDLEQVELWLIEVNNQSIPMLQAKLTTYATLKQELQAQIHKGQ
                     ELLQNQEQPDLDSLAQAVQNCQEIYDRQLAQFSVMEKGLKDATATYQAAKTLQDSNQEA
                     FKAHQELSDLVKVVKGENTALTGRLNLEVYVIRQYFQQILDYANANYIGLLTDNRYSFV
                     LSEEGRRARDHFGLDINVYDQLTGSERSVKSLSGGETFIAALAIALSLSEVVQNTSKGA
                     VVEALFIDEGFGSLDKEALTKAISVLEQIGENRMVGVISHVDDMKEGIAQQLVIIKSHD
                     GSSRIKIVDKG"
     CDS             complement(13268..14476)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_functions="other (smcogs) SMCOG1230:Nuclease SbcCD, D
                     subunit (Score: 253.5; E-value: 8.1e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_18"
                     /sec_met_domain="Metallophos_2 (E-value: 4.4e-10, bitscore:
                     31.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFLHTSDWHVGRTLNGWSLLEEQEWAFQQIVDLAISEKVDGVII
                     SGDLYDRAVPPVDAIKLFNKTLARLVLEEQIPVYAISGNHDGAERLHFGRDFFQHQGLH
                     LSTRLEEAFEPIELENCQIFLLPFIDPIDARIYYKDDEGKEIQGIGDALTYILEDMEKA
                     FDPDKAHVLVTHFAVSKKDDSDGQGLRELMLSETSNTVGGLTNVTSDLFKSFDYVALGH
                     IHTRFASPTKRVQYSGSPVAFNVKEAKRKEEKGVYILELDASGDMSQTFHTLEVKRPIV
                     ALQESFETLMSPEFYKNQPCQKAWFAFDIQLSSRKELEGINVRARLEEIYGTDIVEITF
                     SRLGDVREENLTVDQHLKDLEMQSPQEIVFDFYQTVTGGDVLSERQTALVESVFEEIER
                     SRQ"
ORIGIN
        1 aaagtttatc agataattga cggtaaaatg acaatcctgg agaagtaatt taatttatga
       61 ctaaaaatca gcaaaaatat aattatgact aaggaatatt ttattaacta aatgttgaga
      121 tagcacaagg aaatatttgt gctatctttt ttatttatta ggaaaagaga aaaaattatg
      181 ccaacgaaaa tatggttaaa accagaacaa ttagatttgt atattaaaca tttagaacga
      241 tttagagact tatatagtaa actagactgt tctggtatag taaatttgta acactcctac
      301 ctaataagtt aaactattca ttagaatagg agacataaca tgaaacacta tccagacgaa
      361 acacgataaa aaattgttcg actgcacatt caagacggat gaacattaaa aagcttagct
      421 gctgaatatg gcgtatccca agcctcaatc tctaattggg taagacatta tcgcaaagaa
      481 tgccaaacta ataataaaga aaaatcacag cttgaactca tggaggaggt tcgtaaatta
      541 cgtcaagaaa aggcagagct tgaaaaggaa aatgatttct taaaaaaagc agcggcattc
      601 tttgcaaagg aaatcgatta gaggcatatc gttttattga taactataaa gaagattttg
      661 gtttgcgttg gttgttcttg catatgaata ttcatcccaa tgcttattat aattatctta
      721 aaaagacaag gactaactat catcgtcaaa agaaagctat tcttaatact attcgagata
      781 tctaccatga gtgcaatgga aagaagtaaa tcaattcttc gaaacagaaa gcatcaaact
      841 ttctgatata gagccttcga aagttagtta tagggaggta caaaggaatc aaatcaatac
      901 cactatttat aatgaaaaag gtaatataaa ggatattgat actagcatta taagagatat
      961 gtacgataaa agcaaaccta ctttaaaaca gggagcctat atatccgcta tagcagcttc
     1021 tctagaaggg gggtactgca tttataacag caataattaa aaaaagcgct tagggaaaac
     1081 tattagtgag tttacaaaag acgattgtct tgaaatttct aaagatagtg gaattggagc
     1141 tataaaagga agtactcgag gcattacgat atacgcccta acgaattaca cagctactcc
     1201 tgcagcagta gcaagttcat tgtgcactgc ttcatttggt atcgctaaag aagcatacaa
     1261 attccgtaaa aacttaatca caaaagaaga atttttacta aattcgcaaa tattatgtgt
     1321 tgaagtatca gttagtgcat tatcctcaat attaggacat gctgtaattc caatacctat
     1381 tttaggatcc gttattggaa ataatatagg aactttccta tatgaaatcg ctaaagataa
     1441 tctcacaatg aaagagaaat tactgatagc agattatttc aaagagatac aagaatataa
     1501 ctatttttta gataattaat ttgaattata taatcatcaa cttcagagag attaagaatt
     1561 actataaact tttagggaag gcattttctc ctgactataa tatcgctttt cagggatctt
     1621 atgaattttt aaatatgttt tttaaaaata cgttaacctc tcctattttc tctgcttcag
     1681 gtaaatagat agaaacggtt gtcgaataaa caaaagaagg tacactcaca attgaaagca
     1741 attgactaat aactgcataa atagccaaca attctactcc taatctcgac atcaaggcat
     1801 caaacaccat aataaacaaa acactctcca gaatttcttg accaaccaaa ggaataccaa
     1861 atgttattaa ttcaaattta gttgtagatg taatggataa agccttcaaa atcattggat
     1921 aaaccataaa caagtaacta agcgatatga aagctaagga tacaatcgtt gatatggctg
     1981 ctcccttaat tccgatttgt ggtaccagta cataatttaa cacaacatct attaatgaac
     2041 tgataagtcc aacccacata attggttttg ttttcttttg aactcttaat aaatttgtca
     2101 gcgaaaagtt taataatgtc aatccgatat atggagacat gaagactaaa taaatggtgg
     2161 ataaggacaa tagttgccct ttaaatccat agagctgctt caagattaca tttccaaaaa
     2221 taatgacaaa aaccgcaaag gcaactccga taattaaatc taaggttaga tttgatttca
     2281 ataaatcatc aaacctgtta gtttgccgat tagagtacgc cttagagctt ttaatattaa
     2341 atgacaaact gaatgctcct aaaagtccac caaaagcaaa taagagattc tgaataatgg
     2401 aaattcctga cagagcaatt gaggaattgt tcacagcaaa atgcaatgct atctgcccaa
     2461 taattacttg accaatattt gttaaaacta agggaaaggc aaatttgtta atttcttttg
     2521 aatctatcat ttttcctctc taaaaggctt caaatgtaag taaagatcag atttaactaa
     2581 atttgcataa ataatatgca aaataggagt ttcttctaaa aatgaaataa ttgcctgctt
     2641 acaatcatta gcagatacct cataatcttg ctgtaatagt tctacaatct tgtctaaaga
     2701 aaaattttta gaaatgcaat aaagtatttc tgctcctatt tcatcaaatg aatagtactc
     2761 taatcaagta gatcgtatcc tatgtattca tctgctactt tatttacaat gaaatctctc
     2821 ttacctctta tcacaaaatg ttctttcata cgactactcc acctcctttt tgttcataaa
     2881 agcaggctaa atcagagccc agtaacgttc catctaattc caaggcactg catcgacatc
     2941 ccccaccaca ccatggtagg ggacattctg aacatttccc agaaatatca tcaaatgtaa
     3001 ttgatcttag tttattaaat acagcagaat ggtgccaaat ttcgctaaac ttttgttctt
     3061 taacatttcc agcaactaat tcatctatac cattcatcaa gtcacacccg tatacatctc
     3121 ctttatgatt aattgaacat gctctaactc cagcttgaca agatatttcc cttggcttat
     3181 caaaatttat atctactttt tgatgccaaa cattttctaa taaatctgat ctattataaa
     3241 atgcaagcgg aaaataatgt gtcaaaaaaa catcactttc attaggagga acaattttaa
     3301 atttaacttt gaactctcct ttagaaatcc gctctgttaa atcaagaaaa acaggatacc
     3361 attgtttttt atctgctaaa atactaccgt cattagccct accagtagga caaataacca
     3421 taactgacat atactcaata ccaagcatat cattcaatct tatactctaa agaaaatatc
     3481 tgctaaattt gcaaacaatt gtgctatcaa taatttggca aatgaattag aaatacaact
     3541 tttaagttct tttctctctg ttagaaaatg aataagatac taagcaacaa agagctacta
     3601 taccaaatat taaataattg ctcctaatac taaagttatc agcaaaaata ccagctagga
     3661 aatcagctaa cataaaacta atcgaaataa acaaattata tactgaccat gatactgctc
     3721 tatttttttc tattgacata ttaaatttat aataaaaatg attattgtag ttggaattaa
     3781 gaacacgcat taataaaagg attataattt ggatgattag attagtttga aaaaacatga
     3841 gtatagctaa tactggtaac atcaagctta cttcaaactt aatttttaga taactcccca
     3901 aagccataga tatattaaac ataaatagta taattcccag catatctagt gaaagtccct
     3961 gttcatttaa gaatatccct gcataagaat tgctaatcat aattagagtt gagaatgcta
     4021 ctcctaatat tattaataac catggaatat tttgaatatt atcgaggcta aaaaattttt
     4081 gtttattatt ttgttccttt ttaatctcgg gtaatcctat taaatataat aaactgaaaa
     4141 ttacaaatac aatggatata ataataggat aaatataatt cctatgcaat aaaggtggag
     4201 atataatcgt aataatagca ataaaaatat attttaatgt gttgagattt ttcaaaaatg
     4261 atttatatac aacttcgtca tcaattattt caaaattata agaaataaga actcctgaag
     4321 ataatgattc tgacaatcca aaaaatatcg ctgaaatata tattatattt gattttccaa
     4381 acaataggcc ccataatgct aaaattaata ataaatttga aatagccaaa attttcttgt
     4441 aaccaatctt acttgaaata taacttaaag gaatatcaaa aactgagcca catagctcag
     4501 taataactga taaagtagct atttctgtga acgaaaaacc taagtgcttt aatagtaaaa
     4561 ttcctacaaa gtagtacggt aatccagata gaaacatatt cattccgtat aaattaaaaa
     4621 tcttcttact cataagttac aaactgggtc tctaaaatat tttggactct tctccttaat
     4681 caagttaaca tagcagccac cctcgcaaat ttttaacaat ccacaagata aacacttaga
     4741 attcttcgtt ctaaaagaac gaatccctcc atacaacgga tcatcatacc aaacatctaa
     4801 caaatctttt tcaaaggcat tctgcttagt ttgattaact cctaaaaaag caatgcaagg
     4861 caagatatcc ccattagaca ttatttccat cttagtatat tttgcacgac atccataata
     4921 catttcgcca aactctgaaa attcaattga attatttatc aactccggat aagcggtgaa
     4981 aagatgacat ccctcagtag caaaatttaa attagcttcc cgttgagtta tataatctgt
     5041 aacatactca ttcaaccttc tcaaatcagc taaatcgtat tttttcttta ttttcgtata
     5101 tcctgttacc tcagaataat tagctactga aaatctatct attttattct ctatacaaaa
     5161 atcaaccaat tctataatct gctcatagct ttgctttgta tacactgcat taattctaca
     5221 tttttttcca acctctttaa agtacttcgc taatttaatt tgtctatcag gtctcacccc
     5281 cattaattca aaatttaatt taggatctaa agtctgcaaa gataaaaccg gtgtaatata
     5341 tttagattta gctagaattt ccactgtact tttctttatt aattgggcat tagttgttat
     5401 agtagtcttt atcttcagtt cttcacaagc tatcaacaaa ttatcaatat caaaatatct
     5461 agtcggttcc cctcctaaaa ttgaaacact taacactcca ttatcttttg cttggcgcaa
     5521 aattctttcc caatctttag caggtttggc atttctatct tcacgatttg ctaaaaaaca
     5581 aaaaccacat tttaaatcac agtacatact ggggtatatt actagttcaa gcggaaaact
     5641 caatatgtta tgttttttta attttgctac atgctttctc gcattttgaa gagtctcgtc
     5701 aggatttttc gatgatccct caatattatt atcagaatag atatttaata agagtactcg
     5761 ctctagtttc cctgctttta tttctttctt aaaaaaggac gtagcaattt caaaaccatg
     5821 attttgaacc aaataaagaa aataagcttc actctcatct aactcaattc ggtcaaaagt
     5881 tactttattt atcaaaattc caccaaactt ttctagtcta aataaaaaat cttctgaaat
     5941 tgtcatcata ttgaatacct ttctaaaaaa gcagaggaaa atatagcctc tgcttaactt
     6001 atgggataaa ttactttatc actcccagcc gtcacctttt gccatcacct tccagccgtc
     6061 accttttgcc attgaactag actcaaggac tttttcaagc tctttagaca tatttggtac
     6121 tcctttcgaa tatgatactg tgattatatt tcttttcaac acttacaata aaatattccc
     6181 atatttgcat tttctaacta ctagctaaaa ttttttctaa atgtccttca taagtctttg
     6241 ctaagtgatg acttcctgct aatttcatcg ctccaacaca cttcttcatt tcaataattg
     6301 ctttcacatt tccatcctct ttatattgat aaagattttg tgcatactta aagactaaac
     6361 gttcatatac ttctgtctca ataaaaaagc attgatttag ctgcttttca aaatataaag
     6421 catccataaa tttttctctt tcaacacatg taatatatcc atttaaaagc atcgttgaaa
     6481 ttaatcgtct gttatttgga atttctttgt aaaaatcaga acgcctaaac atttctcttg
     6541 ctaagaccat gaaaacatca tgatttaata catctaaagt attcgagaaa atcaataact
     6601 catagtaccc ccagtattct acactaaaga gataatctgt taaatatgtc aaatcatcct
     6661 ttgtatagta agtttctcct gataaatcct gtagacgaat tttcaataaa ataatattga
     6721 tttgatgaaa tttttctcgc ctatcttcca gttccatctg agaataaagt aattttttca
     6781 taccttctac gtcacgtgtt gacacaaaat gacgtacttt cgataacagt tcgtttaact
     6841 catctctatg aaaatcatgg accgcataca taaattcatc tattggcata ttgatttcat
     6901 ctaaaataaa catgaacttt gaaatcgtta aatctgtttc tcctttctca aatcgagaga
     6961 gctgagacgt tgatatacca gcctttgcga cgtcttttaa tcgtaatcct ctcgattctc
     7021 gaaacttttt aaaaatttct ccaaattttt tcatactaca cctccatcac gcatatatgg
     7081 gaataatttt catttgcttt catcatatca tacaataaag aaaaacaaaa gtgaggatta
     7141 tcacatgaaa aagcaaattt tactaacact tcttcttgtc gtatttgaag gcattatcgt
     7201 tatcgtcgtg ggataaagag tctgggacaa aagtccttta gctccaaaaa gcaacggcat
     7261 aatgtactga ccccaaaaag ttagacaaat aatttaagta aaggatttag ttctgtattg
     7321 tacaggactg agtcctttta gttttacctt aatgcgtttg ttgttgtaat aattaatata
     7381 gtctgcaatt gcttgttcca aatgctcaat tgacttaaac gtcttctcat aaccataaaa
     7441 catctcagac ttaagaatgc caaagaagga ttccatcatg ccgttgtctg gactattgcc
     7501 tttacgtgac atggatggtt ggattccttt ctcctctaaa aaatgatgat agaaatcatg
     7561 ttgatattgc catccctggt cactatggag aattgtattt ttgtaatgtt tctctgtaaa
     7621 ggcttgttct aacatagctt tcacttgtat caagttcggt gacttagaaa gattgtaggc
     7681 gataatttca ctattgaagc catctaaaat tggcgacaaa tagagttttt ggctgcttgc
     7741 tggaatggca aattctgtta catctgtgta gcatttttcc aatggtttgg atgcttcgaa
     7801 ctggcgttgg atgagattct ctgctttcat accaacctct ccttgatatg aagaatactt
     7861 acgtttacgg cgaattctag cggttaaacc aagtactttc ataagacgtt gaactctctt
     7921 atgattaatc acaattcctc gatttctcaa ttcaagagtc attcgacgat agccgtaatt
     7981 tcctttatgc tcagtaaaaa tggcttgaat ttcagcttta atgtcataat ccttatcatt
     8041 ttgatccagc tgttttaagt ggtaataata ggttgaacga gcaagcttaa taatctttag
     8101 aagcatatct aaagaaaact cagttaccaa tcctcggaca atttccgttt ttcttcttgc
     8161 tctttttctt ccctcaatcg gagttctctc aactttttaa gaactgcatt ctccgctcta
     8221 aggtactcat tttctgcttg aagacgttcc atttcttcca gttttttctt tggcttacgt
     8281 cccattttag ataaccttcc tcttgttttc tcaacaatag tatacccgtt tttcttatag
     8341 tgtgcgagcc agttaggaag cgtcccacga tttgggagag catattcaag agaaactcta
     8401 tcttgagaat agcctttata taggacttta tcaatcattt cttgttttaa ttcaggagag
     8461 tagtaacgat tctttccttt tttagcgatt tctattccgt atcgatcaat caatttaatc
     8521 atgtagctaa gattagaaat gtttatccca aatttatttg aaagctgatc taagctatat
     8581 ccttggtttc taagttcata gatttgaacc ttatcttcat aagtcaattt cataataaaa
     8641 acaccccgaa agttagattt tttctgtcta acttttgggg tgcagttcat aaaaccgttg
     8701 ctttttgcat gattgtgata gacttggtga aatagaattg accaaaaatc ttctgaaata
     8761 taacaagaga gtgactcgaa tttaaaaagc tagagttcca caattggaaa tctctagctt
     8821 ttttgtgact gagaactttt tgtcccagcc tctactttct actgactact atcctgcatg
     8881 ccctaagtcg agatagagaa tatctcgctt agtggcatac tctagcgcat gttcaacagc
     8941 ctcaaataaa tctgaagcta gaaacctttt cgtaaagacg gtttcgtctt tacgcttaaa
     9001 tttcgcaaca taactatgtt tagtcatttt ttctccttct aatattcata ttgtccttta
     9061 acaccactat agatccagta aactgcttta tcataaactt gtttaaagga gatacctaat
     9121 cgattggcta catcaagaat tgaaatttgc ttacattcct ctatattcat aaaatatcat
     9181 cattttgtcg tagtattcgg caatgatgga acagatgagg attcttctaa agttttagga
     9241 gttgccttat ctagatcatc taacccagat ttccaaacct gtacttggtt gaccaataac
     9301 ttaccaggta gtttcgaata gttcaaatta accgttctgg tttctgtttg gtttgtcttt
     9361 gattggttgg cattctttaa atcagataca taagttacat tataagagac catggcaatg
     9421 gcttgattcg tagtctgatt gacaaagata tctgcttttt caaaatgata atccaaaata
     9481 tagtccttat acacttggtt catggcatca ttttgacttg tcaattcttg agaataggcc
     9541 gattcagtca tataaggttg aatacgtgta ttattttccc ctagtttttc tttcgtatag
     9601 tactgtgtca aaaattcttt tacagtatct gatgataaaa tacttgcttt atcttctgct
     9661 tgtttgtcct ctacaagttt agctgcagcc aattcgattt cttttcgact ttgtttggca
     9721 gtagaatgtt gaccaataga attagcagta agttgtggtg ttgatgaggt ggatatacta
     9781 aaaaatgagg aggaaattga taattacttc acctagctaa aagttcaacg aattagggag
     9841 acattaggta gcctcatatt actttgatta gtttttgcta taacattgtc aaatatgatg
     9901 acaaaaaaat ccgtccgcac ttttttacga gtaggacgaa ttaaatatgt tatacaaacc
     9961 atcagctttt taacaattct acataaggta gttgttgatg caactacctt ttttctatgc
    10021 tgattagaac aaatttgaca tggctacaac tgcgattatc tgatatagag tattatataa
    10081 actgattcct cctacccctt atccacaatt ttaatacggc tactgccatc gtgcgacttg
    10141 atgataacta gttgctgagc aataccttct ttcatatcgt ctacgtggct gatgacaccg
    10201 accatgcggt tttcaccgat ttgttccaga acagaaatgg ccttggtcag ggcttcctta
    10261 tccagtgagc caaacccttc atcgatgaag agagcttcaa caacggcacc cttgctggta
    10321 ttttggacaa cttctgagag ggatagggca atggccagtg cagcgataaa ggtttcacca
    10381 ccagacaagg atttaacgga gcgttcacta cctgtcagct ggtcatagac gttgatatcc
    10441 aaaccgaagt gatcacgcgc cctgcgtcct tcctcactta gaacaaagga atagcggtta
    10501 tccgttaata gtccgatgta gttagcattg gcatagtcca agatttgttg gaaatactga
    10561 cggataacgt agacctcaag attaagacga ccagttagag cagtattttc tcccttaacc
    10621 accttaacca aatcactgag ttcttggtgg gccttaaagg cctcttggtt actgtcttga
    10681 agggttttag ccgcttggta ggtagccgtc gcatccttaa gtcccttttc catgacagaa
    10741 aactgagcga gctgcctatc atagatttcc tgacaattct gtactgcttg cgctagacta
    10801 tcgagatctg gttgttcttg attttggaga agctcttgcc ccttatgaat ctgcgcctgt
    10861 aattcttgtt tgagcgttgc ataggtcgtt aatttggcct gaagcatagg aatagattga
    10921 ttatttacct caataagcca gagttcgacc tgctctaagt cattagcgag ggctccttca
    10981 gccttgagac tttgctctaa ttcagcagat aatcgcttaa catcttgatt taccttatct
    11041 ttagacttag ttatactctc aatctgcccc tttattcctt taatgtcggc atgaagttgg
    11101 ttgtaggctt cgctattttc cttgacttgc ttattgtaga ggttcagctc ctgatgagca
    11161 agggaaatcc gttcttgata tacctcaaca gactcaagtt ctggatgagc ttcctgcagg
    11221 tcctctaggc gttcttgagc ttggtcaagc actgccttgg cctcttgata ggttttagcc
    11281 aaatctgtcg cttttttttg agccttacct agctcatctt gatatcggat ataatctgtc
    11341 tcttccttat cataacgttt ttgtaactct tgataatact gctcaacctt caggagtagg
    11401 gcttgcccac ggtcagtttc atagtctatc gaaaaatcaa aatcaaaccg tcccttaacg
    11461 tgctcttcta attcttgata gtgcttttca agagttgcct tgactttagc cacttggtca
    11521 agcaaatcct gacgtttaga tgcaacttca ctcaaggtag cctgacgatt tgataaagta
    11581 gcgacttgct tttctttttg agcttgaagc ttctccacct gatccatgag atttttcaag
    11641 gccacttcat cagcctgtgc tccaccaaca ttagggtgtt ccagagcacc acaaaccata
    11701 caaggatgcc cctcctctaa ctctgcctgc agttggacaa taatgagttg acggcgtgaa
    11761 accaaagtcc ttcttaactc ctcttccaat tctttgagaa tttcttgagc ttgatcaata
    11821 tcaaaagata acgtttgatg acgtttttcg gtctttgtca actcctgatt caagttctct
    11881 atttctttca ggtcctgagc aagttgattc tccacactgt agcccacaat ctggaagagt
    11941 ttttcggcct catgtaaact atctaaacta agacgattag cctccaagtc agacaaggac
    12001 ttgttaagca tctcaacctc ttttctagcc tgctgatagg tctcttccaa ctgcttgtag
    12061 ttagtcgttg aacgtttgat tttctcctgt tcttgggcaa gactctgggc atagataata
    12121 ttctctttcc aagtttcaag ctcctcttct ttttgaagaa aatccttaga ttgaactgtg
    12181 agttcctctt ttttagcctt aacatcctca aacgcctgtt gcttttcact taaggcttct
    12241 tgagcaattt caaggtcctg ctctaattgc atcaactgtt tccgatactg cttcaaggtc
    12301 cgaatggttt cctgcagacc ttgagcaaac tgtaattcct ccagatgcac ttttgcctct
    12361 gcctgtcctt gagccccctc ctcaatttcc agacggtaac gttccttggc ttgctccaat
    12421 tcttgaaaaa tctttgccaa atcttgggca gtttgcaagc tcttctgcag ttgtgccaaa
    12481 tcctcgtggg cagccttcaa gatacttttt tgcttcgtaa cattttcttg acgctgagac
    12541 aaaaactctt caagacgtgt caatttttca gaggctggcg tttgctccaa gacggataat
    12601 tcttcctcag accaaacctg actggcaaaa tgaccatcta gctgagcctg acgcttttcc
    12661 atatccttat tactctgacg aagacgctct tccaagctct tttgaaaatg gtcaaaaata
    12721 cccgttccaa agattttctt taaaatttga gtcttggtct tagaatcttc tttcaagaaa
    12781 cggctgaaat cattttgtgg aaggagaata atctgtttga actgctcagc attgagcccc
    12841 aaaatctgct caatctggtc actcacttcc ttgatcttat ccccaagctt ttcaatttcc
    12901 tgaccaccaa tcttatccac aatgactaga gaagccgtcg ccttttgcat ggtagtgccc
    12961 ccaccctgct tggccctctc ttgctggaga actcggtcaa tgcgataaag gtgattgcct
    13021 tgttggaaat agaaagtcac cttggtcaaa tcatcctctg gaccagcgaa agttgaccgc
    13081 atctcctcaa cattacgatc accactggtc gtagcaaaca aggctaccgt catggcatca
    13141 aagagagtac tcttaccagc ccctgtatcc cctccaatca aaaagagggg agcatggtca
    13201 aactgagtga aattaataac ttccttacga tatggtccaa aattggtcaa ttctaactgg
    13261 actggtctca ttgtcgactc ctctcaatct cctcaaaaac actttccaca agggcagtct
    13321 gtctctcaga taagacatcg cccccagtta ctgtctggta aaaatcaaat acgatttcct
    13381 ggggcgactg catttccaaa tcttttaagt gctgatcaac ggtcaagttt tcttccctaa
    13441 catcacccag acgactgaaa gtaatttcta caatgtctgt cccataaatc tcttccagtc
    13501 gggcacgcac attgataccc tctaattcct tacgactaga cagttgaata tcaaaggcga
    13561 accaggcttt ttgacaaggt tgattcttat aaaattcagg tgacatcaag gtttcaaaag
    13621 attcctgtaa agccacaatc ggccgtttaa cctctagagt atggaaggtc tgagacatat
    13681 caccagacgc atccaattca agaatataga cacccttttc ttccttacgc ttggcttctt
    13741 tgacattaaa ggcgactgga ctgcctgaat attgcacgcg cttggtagga ctagcaaaac
    13801 gcgtatggat atgccctaag gcaacataat cgaaagactt gaaaaggtca ctggtcacat
    13861 tggtaagacc acctaccgta ttactggttt cagacaacat caattctcga agaccctgac
    13921 catcgctatc atccttctta gaaaccgcaa aatgcgtcac caagacatga gctttgtcag
    13981 gatcaaaagc tttttccata tcctcaagaa tgtaggtcaa ggcatcacca atcccctgaa
    14041 tttcctttcc ctcatcatcc ttatagtaaa tacgagcatc aataggatcg ataaaaggca
    14101 gcagaaaaat ctggcaattc tccaactcaa tgggctcaaa agcctcctcc aaacgtgtac
    14161 ttaaatgaag gccctgatgt tgaaagaagt cacgcccaaa atgtaaacgt tcagccccat
    14221 cgtgattacc actaatcgca tagacaggaa tctgctcctc cagtaccaag cgggccaagg
    14281 tcttattaaa aagcttaatc gcatccacag ggggcaccgc acggtcatag aggtccccag
    14341 aaatgataac cccatccact ttttcgctaa tagccaaatc cacaatttgt tgaaaagccc
    14401 actcctgctc ctccaacaaa gaccagccat tgagggttcg tcctacatgc caatctgacg
    14461 tatgtaaaaa cttcatgaca acctcctcat tcattttgtc ttacttctat tgtaccttat
    14521 caagctaaat actgcttaaa agtttcacag gctttgatag ttttcccgtt ttttagctgt
    14581 aaagatcaaa aaatctctcc caagctatcc tgtactgacc ccaaaaagtt agacaattta
    14641 tgtaagcaaa ggatttagct ctgtattgca caggactgag tccttttagt tttaccttaa
    14701 tgcatttgtt gttgtagtaa tcaatatagt ctagattacc ctgcctcaat tggttaagta
    14761 atttaaatac ctctaaccaa gaaaatcaat attatctatt cttttaattg acttttatag
    14821 attctaagca ttatcatata ggttggtact agtgcacatc ttgtatttta ggcaataata
    14881 tttactcact tttcgttatt gtcagtaccg atccttttta aatttttcac catgaaaacc
    14941 taaaaataat ccgaacccta agggctcctg actttttact ttattctagg ctttttttat
    15001 ccgtagcttg ttagctgact tggaactagg catgtagtat ttactatttc cctacttgag
    15061 attttttata agtcacatgc attattccat ctgaacgaat ggtatgattt ttatttcttt
    15121 tagagaaaca ccggtaatag ctaattccta tcttaaatca cttgaaatat atttataatg
    15181 tgttggagtg ctaatcagta ccgcttgtag atttttggaa gatactaaca cactaatgat
    15241 ttaatctcct ttaaaacatg aaaagagaag cctccaaagc ttctctttta taattatcaa
    15301 ataatgtaca actagattct taataactac ctaatttagt ggttcaatca tgaagcttaa
    15361 ttgatagcta tctgctgagc taagcaagaa ttcgtcatga actggagcac cccatgtgtc
    15421 gtcaccacct acacccattt gagcagcaag aactttaatc catgtagcat cagattcttg
    15481 caactcatat tggtgacgag cattttcaat ttgttcagta ctgttacgca aagcactgaa
    15541 ttcgaatgct ttattaagtg cggtgaattt aagaccatta tggttatcat cagatactgt
    15601 gaattcacga gtaccatagt gattaccaga ttcttgtggc attagatatg gagcaaatgt
    15661 cttttcaaca gatgtttcat atcgaccaag ataggcacca ggaagtttat cacggtagct
    15721 ttcttctgca ccgtatccat aatagctaag gtttgtaaat tgtgaaccga tagcaaattc
    15781 tagaccaaat tcagggaagt ttggcaaacc tgctttacca tcatagtttg cagtaacaaa
    15841 gattcgaccc ttgtagtcaa cttgataagt taccttaact tcgacatcag acaagcctgg
    15901 caattcatga acataagtca ctttaacaga gtcgtcttcg atttgaattt gagtatctgt
    15961 aactttacta tagtttccag caaccttcca gcctgccatt tcgaatggat atccagcacc
    16021 acgatcgttg tcagtgtaag cacgagtgaa gctaagttta ggacctttct caatgaattc
    16081 aacaccatta tacttagcag atactaaagt attttgtgca cgtgaaagca agattgagaa
    16141 gttttgtcct tgaataccga tgttgaagtc gccttcaaca acattcaaag gtgctttaac
    16201 tggtgtttca gtgctaatct tttcaacaac atattgacca cgaacaattt catgaccttt
    16261 aggagcccat tcagttgctt ccctcagaac acaagcaact tcgtaaattt gttcagaatt
    16321 tgaagcctcg actacaaagt taactgggaa tgttgcttct tcgcctggtt taacatcaaa
    16381 gtgatattca ctttcactaa cttttctacc atcttcgtaa actctagcta ggaaagtata
    16441 agcagaaaga tcttcgaaga gattatcatt cttgatagtt actgattttt catcaacagc
    16501 aatcttaata ttagagtaaa gatgtttaac tgtttgaagt tttggagtta gggtacgatc
    16561 tgcaaagacg ataccatttc cacaaaattc gtagtcagaa ggtctatcat gccagtcacc
    16621 accatatgat aggaattcgc taccatttgg aagtgttttg taaatagctt ggtcaatgaa
    16681 gtcccaaata aatccacctt ggtattctgg atatttctct aagtcagtgt agagttgcaa
    16741 tccaccacca gagttaccca ttgtgtgcat gtattcacat gaaatataag gtttttgagg
    16801 tttgttagtt aggttacctg aagcaaagtg tttatcacta acgcttgaaa gatcaactag
    16861 tttaccagtt gtgaggtatt cttcgatatc agctggtttc gcatacatac gactttcgat
    16921 gtctgtaatg taatcaaact cacgacacca tgcaacacct tcatagtgaa ctggacgagt
    16981 attgtcaaca ctacggaagt aatcagccat gtcagcaata tctttaccag catatgattc
    17041 attaccacaa gacc
//
