LOCUS       gnlProkkaFNIHADKP_46   16317 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FNIHADKP_46.
ACCESSION   gnlProkkaFNIHADKP_46
VERSION     gnlProkkaFNIHADKP_46
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 04:32:18
            Original ID  :: gnl|Prokka|FNIHADKP_46
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16317
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16317
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3535:11317]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3536..11317
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..16317
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16317
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(138..1493)
                     /locus_tag="ctg46_1"
                     /transl_table=11
                     /translation="MKAKDNQADRGDQPLSEKHHMQIPWYDVIVSEERQADHATLEERA
                     SLVGRVGIMLLACGTGAWRVREAMNTVARALRMSCSADIGLISLSYTCFSNNHAYSEVL
                     SLPKSGVNTDKLDALERFVRHFDKEYATQTVRDIHHRLDQIQKMSGNYDPLRAGLAAAL
                     ACCAFVFLLGGGPIEMVCCFVGAGIGNWLREIMIRRNWTLLACIGVSVAVACLVYFIAF
                     RGLEMGLGIAARHEAGYIGAMLFVIPGFPFITSMLDISKQDMRSGMERLLYALMITIVA
                     SLVGWLVAMVVHLRPENFVDLGLSPILLLVYRLIASFCGVFGFSVMFNSPRRMAIQAGL
                     IGAVANTLRLELVDLNTIPPAAAAFIGALVAGLIASAINRVDGYPRISLTVPSIVIMVP
                     GLYIYRAVYNIGLNNIGVGAEWMTRAALIIMFLPLGLFTARLIMDSRWRQSD"
     CDS             complement(1673..2026)
                     /locus_tag="ctg46_2"
                     /transl_table=11
                     /translation="MDYEEELETKGYIDCLLHELHEQPQLIRQTNIEEVVERTKEEIIR
                     DGFHGYELRRHVFRMILRIDFILTTESVRLSQEGRDAIDELRRIANGQKKEDPRRFLRI
                     RHFLAQRFQHHMQ"
     CDS             complement(2144..3523)
                     /locus_tag="ctg46_3"
                     /transl_table=11
                     /translation="MMDPKKLATTEYYQHRFRNFSTMIIMPSTILFLGLLLFLIFARRE
                     VTVLTAAEIEPVKAAVTVQATAANRIVSNRMKEGKRVKKGETLLVYHDVANPTQIKLLK
                     QQLATLKEQQQQLDVLKQSVTENKDLFSKADRFGYQQQVQDYLSQRRVLTLTAEAEQAT
                     QTVASEKNKEIDRLLSASIQTSQAKMAAISEAKAAIQANKPLPSRHAYHYLYQQYESEI
                     KNTDAEAQANLKRQYLAQLQTQLDEEQTNLTSLEQQRAGQKQADVSAQKAGETQANLTA
                     LQSRLQQTAVAEQTKVQQQVQADEAKLATLNDETQNYHVKASASGVLHLETALAGNQYV
                     PSGSVLARILPDLTEQTVADIKLGVSPTEIMSIKRGQKVRLRIAENVPTPTILDGRVYA
                     IDVAPTRDPKVGNFFTVKARVKLSKSQRQSLYYGLAGQASVITGTKTYWDYFADKMFNH
                     R"
     CDS             complement(3536..5728)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 311.7; E-value:
                     1.6e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_4"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.9e-41, bitscore:
                     132.5, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1107.2,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKYTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSL
                     AHLRELAKTNQDGTTALGIVRAAEALAFETKPVQANMQLFDLEDVPYPFIAHVLKRGEL
                     LHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKEDKGS
                     LFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGL
                     LVAYLLQAVLTYGQNFLMAVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFAD
                     ANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLVSLIAVPCYLVIVFAFQRPFD
                     RLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKKSFSYTKADQ
                     LQQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKL
                     QMARVANNRLNEVYLVESEFKEQRHLTERHLIEGPIRVRDVSFKYGFGQDVLKNVNLEV
                     PENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPVKDINLTTLRQYIEYVP
                     QDPFIFSGTVLENLTLGSRSDVSEQDLTQACLAAEIAADIANLPQQWQTKLSESGSILS
                     GGQKQRLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIA
                     AKTEQIVVMDHGKIVEQGDHATLLAQDGYYARLVHE"
     CDS             complement(6004..6156)
                     /locus_tag="ctg46_5"
                     /transl_table=11
                     /translation="MNNKKEFQRQMKSSVISDDRLTEILGGGRPISSTFNNLRKWLIEQ
                     FQGKH"
     CDS             6343..7638
                     /locus_tag="ctg46_6"
                     /transl_table=11
                     /translation="MTLMSDTTYFFITLPIFLTGIYFLTFVFESRSRVIHITFWSVFGT
                     LLSLLLSTYGEVFFFIIYACYVAKTTSRSNVFWVFIFMEVNLIVITAHTTSTQALVLLK
                     ARLDPCILIADSVINLAVFIATIWLLSKKKEQIIKLRDLVREQNKLQRSILIYTGANCA
                     SLYCFEATWNLIDLNNFLSWLSLGVFLLSVVISLYSIFFILKSYKYYIELIWIKRAESS
                     QRAYYATLAQQQKRTDKLLHDYKNLLATLQLSMDQSTHNISSETRDVVSKAQQALSQVE
                     FNQETFDAIKSDSLKSLLYLKWTEALHQNIKMYVHIEGIIEPLDSSTSFAVIRALGILI
                     DNALEETSRSGNSKFSVLLINSSSYLEVNVINDVTAGFELSNLNQSGFTTKGHGRGKGL
                     TIINELIEQNKKISLKKKVKDNQLKITLFVWR"
     CDS             7643..8419
                     /locus_tag="ctg46_7"
                     /transl_table=11
                     /translation="MSKNKTILNIYILEDNPDYLTFIQETVQQYLLIEELPAKIRLATT
                     SATELLATIDWSAINDSIFLLDIELGDSATSGVDVATAIRKKSYYVDILFITSHVDEAL
                     RILEHKIAPLDMINKNSPSKTEKKIRNNILYAIKRLKARQVASPRLFSYSINSSIFSLE
                     MDELIYIQTAPGVSGTLELHAENEITTFPGNLKELATKYTNLCRCHKSILINPAHVLRL
                     DITNRFVYMDNQDKLEVSIRRIGELRNILTGTRALS"
     CDS             complement(9905..9994)
                     /locus_tag="ctg46_8"
                     /transl_table=11
                     /translation="MVSFTDSFGADQTPIAMLVGMGLLSMDDA"
     CDS             complement(10028..10327)
                     /locus_tag="ctg46_9"
                     /transl_table=11
                     /translation="MNKLKWFAGGNERAEQAIQLIDELLHDFDDSSFRSDRIRTVLRNN
                     KEALIHKQAAVPFILSRMNLEISNALLQNNILLTKQQSDKFEQLSSLANIRYGY"
     CDS             complement(10505..10663)
                     /locus_tag="ctg46_10"
                     /transl_table=11
                     /translation="MTKLNEAELSKISGGIGPLAIPVAAILGFLATDAWNHADELVAGV
                     KQGWERS"
     CDS             complement(11132..11317)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_11"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.7e-08,
                     bitscore: 27.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHLKTLNTADLASISGGDNGNLWTFIGKAIGSTARSWAEGAMFA
                     PAIGPAKEIVDKLNGN"
     CDS             complement(11377..11562)
                     /locus_tag="ctg46_12"
                     /transl_table=11
                     /translation="MTMRTGLALKEISGKMLELTSGGNVPLSNCSVDPPNERHPPAYES
                     AFKYKLPIVHPIKVAT"
     CDS             complement(11948..12133)
                     /locus_tag="ctg46_13"
                     /transl_table=11
                     /translation="MSTRLTKLVDYGLIIATIIFAIYTVTSAFGWTNHGSFVTPMLILM
                     TLLMLLSEREEKQKSA"
     CDS             complement(12183..12989)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_14"
                     /sec_met_domain="Abi (E-value: 7.3e-15, bitscore: 48.1,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKRHLLLSPGFCVLYILLLVVLISQLLLIPAVYMLKLDFWAGN
                     ILFKAIILLVMIALNWLLLKQVIVLKVTLSRPRLKPVIIWGLVLMLIAWFTVTNRTPID
                     VLQAAVIGTIAAVPEEYLFRGVMLGELIRAFYVAHHRHAKYQLLVCIGLSSLVFSLAHL
                     SNLPAQGLVITIAQVIQAFGMGAIFAALYIRYGSLLMPILIHFLIDFVITLVSGPYPKE
                     APSDPNAITMTIVHAFLIAGIYLAIALRLFRRGQNNEKFLARLSHS"
     CDS             complement(13310..13750)
                     /locus_tag="ctg46_15"
                     /transl_table=11
                     /translation="MAFSVAFSQALEITAYVNAKSQAQHEDYLSIQKISEMLNIPVPSI
                     KKISSTLKKSGILTSKTGLNGGLRLAKTPQTITVYEILAAIEGTAPLFKLHQEIDPAAF
                     VNGERVTSWLVASTNVLNRAEDAMVQVLKQTSIADLAEAAEA"
     CDS             complement(13805..15232)
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 325.1; E-value:
                     9.2e-99)"
                     /gene_kind="transport"
                     /locus_tag="ctg46_16"
                     /transl_table=11
                     /translation="MSKEEDKELINDGLADDTVIEETDAAITQSQRMSATQVIILGLAL
                     IGAFLGVLDTSIVYTGTVKMAAQLHLNAGALSWVQVAYALTYAGLMLVGGKLGDIYGRK
                     PLFIASLAIFGVGSLAVGAATNALVMISFRAVQGVGAAILAPNCLALLTDTFQGKARQR
                     AIGYYASVIGAGAAVGLVIGGFFATFASWRVGFYMNGPIALIMVGIAARYLPSAKRQTG
                     KIDWIGTILSVLAMTSISYGLDGSPWPIPTLLISAVLWIAFIASQGRVAHPTMPLEIFT
                     DRERMASYVSSLLFSAAAIGFWFYTPQFMQGVLGLTPFMTALGMVPMAILLFIVAVKAR
                     TFVDRWRNSRVMIFGFVTVLLSLAELAVASRFANYWFLLLGTLGFAVGFALAFATLATS
                     GLARIRPEISGAASGVYNTARQFGGALGLAIFAASTASLSKIADVFGQAMLIGVGMTIV
                     GLILVVTLIIPAEKAAK"
     CDS             complement(15405..15737)
                     /locus_tag="ctg46_17"
                     /transl_table=11
                     /translation="MNMVQRNQILFILTGLNLSLKKAASGGLMETEAREVVDEALAILK
                     RPNVLKNRAADYALSRLYARFTRLIGLQGMKLSAEANQWWQAVKDFMENDIHGELSQVG
                     GPHFII"
ORIGIN
        1 ctgtacaacc ttcaccttga actcacttga atatttagtc ataaaaatac cccacaatca
       61 ttagagtatc tgtctaacaa ttatggggca cttcattttg aagtggggtt atttgtgttg
      121 ctaaaaagtt atactgatca atcgctttgc cgccagcgag aatccataat caagcgagcg
      181 gtaaacaagc ccagcggtaa aaacataatg ataagtgcgg cacgcgtcat ccattcggca
      241 ccgacgccaa tattattcaa tccaatattg taaactgccc ggtaaatata caagccaggc
      301 accatgatga cgattgatgg cactgttagc gaaatccgcg gatagccatc aacgcgatta
      361 atcgccgacg caatcagtcc ggctaccaac gcgccgataa atgccgccgc agcaggggga
      421 atcgtattga gatccaccaa ttcaagccgc aacgtattcg ccactgcccc aatcaacccg
      481 gcctggattg ccattcggcg ggggctgtta aacatcaccg agaatccaaa gaccccacaa
      541 aagctggcaa tgaggcgata aaccaaaaga aggatcggac tcaggcctaa gtcgacaaag
      601 ttttccgggc gtaaatggac aaccattgcg accagccaac caaccagcga agccacaatg
      661 gtaatcatca acgcatacag tagtcgttcc attcccgagc gcatatcctg cttcgaaata
      721 tccagcatac tggtgataaa tgggaagccc ggaatcacaa acaacatggc gccgatatac
      781 cccgcttcat gccgcgccgc aatgcccagt cccatttcca gtccgcgaaa agcgataaaa
      841 taaaccaagc aggcaaccgc cacactgaca ccgatacaag ccagcagtgt ccagttacgc
      901 cgaatcatga tttcacgcag ccaattaccg atccctgcac caacaaaaca acaaaccatt
      961 tcgataggac cgccgcctaa caaaaagacg aaagcgcaac acgccaaagc agctgctaat
     1021 ccggcgcgca acggatcgta attgccagac atcttttgaa tctgatcaag tcgatgatga
     1081 atatcccgca cggtttgagt cgcatactct ttgtcaaaat gacgcacaaa acgttccaac
     1141 gcatccaact tgtcagtatt cacaccgctt tttggcagtg aaagcacctc agaataggca
     1201 tggttattgc taaagcaggt atacgataag gaaattaagc caatatctgc tgagcacgac
     1261 atccgcaatg ctcgagcaac ggtgttcatc gcctcacgca cgcgccacgc cccggtacca
     1321 cacgccagca acatgatccc gactcggcca acgagtgacg cgcgctcttc aagggtggca
     1381 tgatcggctt gccgctcttc gctgacaatc acgtcatacc acggaatctg catatgatgt
     1441 ttttctgaaa gcggctggtc tccccgatcc gcttggttat cttttgcctt cataactcgt
     1501 gctaatcctt cttcttatag ggattgtctt tttcaaaaaa attgaaaata aacattcact
     1561 attctagcac aattcataac agggtgtatt tttgactttt tgaaactaat gaatttgaac
     1621 gccttattca tgacaagcac gcacaaacta gcaatcattt ctcggtctca acttattgca
     1681 tatgatgttg gaatcgctgc gccagaaaat gccggattcg caaaaagcga cgaggatctt
     1741 ccttcttctg tccattagca atccttcgta gttcgtcaat tgcatctcgt ccttcttgac
     1801 tcaaccgtac actttcagtc gtgaggataa aatcaattct tagtatcatc cgaaaaacat
     1861 gccgtcgtaa ttcatagcca tgaaaaccat cgcggataat ctcttccttg gttctttcca
     1921 caacttcttc aatattcgtt tggcggatga gctgcggttg ttcatgtaat tcatgcaaca
     1981 ggcagtcgat atagcctttt gtttctaatt cttcctcgta atccatacgc cgatcaccgc
     2041 ctttcatttg actaacttga tccgcatcgt tttttatggt cattttctta aataatgggc
     2101 atcgcctttt cgctactaaa caacaaaagc ggtaaatacc gatttatcga tggttaaaca
     2161 tcttatctgc aaagtaatcc caataagtct ttgtgccggt gataacagat gcttggccgg
     2221 ctaatccata ataaagggac tgccgctgcg atttagataa tttcacccgc gccttgaccg
     2281 taaagaagtt accaactttc ggatcgcgtg ttggggcgac gtcaatcgca taaacccggc
     2341 catctaatat ggtaggggtc ggcacattct cagcaattcg caggcgtact ttctgcccac
     2401 gcttgatgct catgatctct gtcggcgaaa cgcctaattt tatgtcagca accgtttgtt
     2461 ccgttaaatc cggcagaatt cgtgccaaca cgcttcctga agggacgtat tgattcccgg
     2521 ccaaggcagt ttctaaatgc aaaacgccac tggcacttgc tttgacatga tagttttgag
     2581 tttcatcatt caaggtagct aacttagcct cgtctgcttg gacctgttgc tgaaccttcg
     2641 tctgttccgc aacggctgtt tgctgcaacc gactttgtaa tgcggttaga ttagcctgag
     2701 tctctcccgc tttttgagcc gatacatctg cttgtttttg accggcccgt tgctgctcta
     2761 aagacgtcaa attggtttgt tcctcatcca actgtgtctg taattgagca aggtactggc
     2821 gtttaaggtt cgcctgtgcc tccgcgtcgg tattttttat ctcactttca tattgttgat
     2881 aaaggtagtg ataggcgtgg cgactgggca agggtttgtt cgcctgaatc gccgcttttg
     2941 cctcggagat agcggccatt tttgcttggc tcgtttggat actggcgctt agtaaccgat
     3001 caatctcttt gtttttttca ctagcgacgg tttgggttgc ctgctcagcc tctgctgtca
     3061 gtgtcagcac tcgccgttga ctcagataat cttgcacctg ttgttgatag ccgaatcggt
     3121 ctgcctttga aaaaagatct ttgttttcgg taacactttg tttcaaaaca tccaattgct
     3181 gctgttgctc ttttagcgtt gccagttgct gcttgagtaa tttaatttgt gttggattgg
     3241 cgacatcgtg gtaaacaagt aaggtctcgc ctttcttcac gcgcttgcct tctttcatgc
     3301 ggttcgagac gatccgattg gcggccgtcg cctgaactgt cacggctgcc tttaccggtt
     3361 caatttcggc agctgtcagc acagttacct cgcgccgagc aaagatcaga aacaatagca
     3421 agcctaagaa aagaatcgta ctaggcataa taatcatcgt tgaaaaattg cgaaagcggt
     3481 gctggtaata ttcggtcgtt gcaagttttt tgggatccat catctaaagc tcacctcact
     3541 catgaaccag gcgcgcgtaa taaccgtctt gggctaacaa cgttgcatgg tcaccttgtt
     3601 ccacaatttt gccatgatcc atcaccacaa tttgttcggt tttagccgca atagttaagc
     3661 gatgggcaac aaaaataatg gtccgatccg tcattgccag caagcgatcg acaatttttc
     3721 gctctgtaat ggtatccaga ctgctggtcg attcgtcaaa aatcagtact tttgccggtg
     3781 acaacaaggc ccgtgcaatc gccagccgct gcttctgacc gcctgataaa atactgccgc
     3841 tttctgacaa tttggtctgc cactgctgcg gtaagtttgc gatgtctgcg gcaatttccg
     3901 cagccaaaca cgcctgcgtc aaatcttgtt ccgaaacatc cgaacggcta cctaacgtca
     3961 aattctccaa caccgtgccc gaaaaaataa acggatcctg aggtacatat tcaatatatt
     4021 gccgtaatgt tgtcaggtta atgtctttga ccggaatgcc attaaacgtg atggttcctt
     4081 tatcggcatc aaccgggtaa aagccaacta ataattttgc taatgtcgac ttaccagaac
     4141 cgctcatgcc aacaatggta tatttagcat tttccggcac ttcaaggttg acgtttttca
     4201 atacatcttg gccaaaacca tatttaaacg agacatcccg aacgcgtatc ggaccttcga
     4261 ttaaatgccg ctccgtcaag tgccgctgtt ctttgaattc cgattcgacc agataaactt
     4321 cattcaggcg attgttagca acccgcgcca tttgtaactt tggctgtagg ttgatgatgc
     4381 tttcaagcgg attcgtaaag tatgacagca gtgcattaaa ggtcagcatc tgccccaagc
     4441 tcatccgatt ggcaatcacc aaacttgccc caatccacaa caccacaacg ttcaacgcca
     4501 gcttcaacag acctttaatc gcttgctgta attgatctgc cttggtgtaa ctaaacgatt
     4561 tcttcagata ggttagaaat tcccgatcaa cccgttcata gctaactcgt tcgccggtca
     4621 gggacttgat ggtttcaatg ccattcaaat cttcaataat cgatgaactc aagattgcgt
     4681 tactttccat cgtctcttgg ttcaaccgat caaacggccg ctgaaatgca aaaacaatca
     4741 ccaaataaca cggcacggca atcaatgaca ctaaaaacaa agtcccattt tggatcccta
     4801 gaacaatgcc taatattagg acaatccaga catccaaaaa caacgtcata atcgtattcg
     4861 ccagcgcgtc aataatttta ttggcatccg caaaccgcga cacaatctct ccggtccgcc
     4921 gagttgaaaa aaacgacatc ggcaattcat ataagtggcg cacataccct aaaatgacat
     4981 caatcgcaag ccgctgcccc aacaccgcca tcaaaaaatt ctggccataa gtcaacacag
     5041 cttgcagcaa gtaagccacc aaaaggccac tagcaatcat ccccatcgtc gtccgcatgg
     5101 cattcggtat atacgtatca ataatagact gcaaaaaata cgacccaacg atactaatga
     5161 ccgtaatcaa taccgcggcc agaataatgt tcgcgataat acctttttgc ttagccagca
     5221 tgggtacaaa cgcaaacaaa ctgcctttgt cctccttacg cggctgatac tgcggcgccg
     5281 gtgcaataaa gatggccaca cccgaccatt ctttttcaaa cacctctcgc gaaagccagg
     5341 tcatgcgcac tgacgggtca ggatcgccaa tcagaatact cgtgcgcgtt gctttaaaaa
     5401 caacatagta atgaagcaat tcaccgcgct tcagcacatg ggcaataaac ggataaggca
     5461 catcctcaag atcaaacaac tgcatattcg cctgcaccgg tttcgtctca aacgctagtg
     5521 cttcagcggc ccgaacgatt cccaaagccg tcgtgccatc ctgatttgtc ttcgctaact
     5581 cgcgcaagtg ggctaacgaa tagtccgacc cattgtattt aagcagcatg tttaacgcag
     5641 ccacaccaca gtcacgctcg tcaacttgtg cggtgtagaa acgtttgtag taggtgatct
     5701 ggcctagttt tggggtgtat ttaaccatta actctcctcg cttattaagc cattagattc
     5761 aggcctcttt tatgagccga tataccatga cgtttagtca aaaatacagg tagtgaatcc
     5821 ccaaatttgg ggttaccctt ttgatataag cactgtaaga tttagttttt tacatttaaa
     5881 atgtgtggta gtatatttta gagcaggatt aatagcgtat aaaaataaat attaaaatta
     5941 aaagcacttt tatatatcta aatatttatt tttatacgtt gaaggcaatc gtctgtctgg
     6001 cctttaatgc ttcccctgaa actgttctat gagccacttt ctcaaattat taaatgttga
     6061 gcttattggt cggccaccac caagtatctc cgtaagacga tcatccgaaa ttacgctgct
     6121 tttcatctga cgctgaaact cctttttgtt gttcatttca acctacctcc tacgatttat
     6181 tcttctgtat ttaacctaac atgtcgtgag ctttttaggg cctacaaaaa ataaacgtcg
     6241 tgttttggcc atttaacgtt atatcgttag catatgacgt catttatttt cattcggtat
     6301 gaagaacttg ccatactttc ataactagcg gaggttttct atatgacact gatgtcagac
     6361 acaacctact tctttataac ccttcctatt tttttgactg gaatttactt tcttaccttc
     6421 gttttcgaaa gccgttccag agttatccac attacttttt ggtcagtctt cggaacgctt
     6481 ctgtctttgc tcctttcgac ttatggcgaa gtcttctttt ttatcatcta tgcgtgttat
     6541 gtagctaaga ccacttcacg ttcaaatgtt ttctgggttt ttatctttat ggaagtcaat
     6601 ctgatcgtca tcacagctca cactactagt acacaggctt tggtcttgct caaagcacgc
     6661 cttgatcctt gcattttaat cgccgactca gttattaact tagcagtatt catcgcgact
     6721 atctggttac tatctaagaa gaaagaacaa attataaagt tgcgcgactt agttcgagaa
     6781 cagaataaat tgcaacgttc cattcttatt tacacaggcg caaactgtgc gtcactctat
     6841 tgttttgaag ctacttggaa tctgattgac ctcaataatt tcttgtcctg gttaagcctt
     6901 ggcgtattcc tactttcagt tgtgatcagc ctttattcaa ttttctttat cttaaaatcc
     6961 tataaatatt atatagagct catctggatt aaacgggcag aaagttccca gcgtgcttac
     7021 tatgcaacgt tagcacagca acaaaagaga acggacaagc tccttcatga ttacaaaaac
     7081 ttattagcca cgttgcagtt gtcaatggat caatcaactc acaacatttc ttctgagacg
     7141 cgagacgttg tttcaaaggc acaacaagcg ctatctcaag tcgagttcaa tcaagaaacc
     7201 ttcgatgcaa ttaaaagcga ttcgttgaaa agtctactct atttaaaatg gacagaagcg
     7261 ctacatcaga atatcaagat gtacgttcac atcgaaggga tcattgaacc gctcgatagc
     7321 agcacttcat tcgcggtcat tcgtgcactc ggtattttaa ttgacaacgc tttagaagaa
     7381 acaagccgct ccggaaactc aaagtttagt gtcttattaa tcaattcaag ctcgtacctg
     7441 gaagttaatg tcatcaatga cgtgaccgcg ggatttgaac tatcaaatct taaccagtct
     7501 ggatttacca ccaaaggcca tggtcgcgga aaggggttga ccattattaa cgagctgatt
     7561 gaacaaaaca aaaaaatcag ccttaagaaa aaggtcaaag ataaccagtt gaaaatcaca
     7621 ctttttgtat ggaggtaact ttatgtctaa aaacaaaacg atcctaaaca tttatattct
     7681 cgaagacaac cctgactatc taacctttat ccaagaaact gtgcagcagt accttctgat
     7741 tgaagaacta cccgccaaga tccggctggc aacaacgtca gcaaccgaac tgctcgcaac
     7801 tattgattgg tcagccatca acgatagtat cttcctcctt gatatcgagc tgggagattc
     7861 agcgacaagc ggcgtagatg tagccacagc cattcggaaa aagtcatatt atgtcgatat
     7921 cctcttcatc actagccatg tagatgaagc tttaaggatt ttagagcaca aaatcgcacc
     7981 tctggacatg atcaacaaga actcaccttc aaagacagaa aagaaaattc gaaataacat
     8041 tctttatgca ataaaacgtc taaaggcgcg tcaggtcgca tctcccagat tatttagcta
     8101 cagcatcaac tccagtattt tttcacttga aatggatgag ctcatctata ttcaaactgc
     8161 tcccggcgtc tcagggacac tggagcttca tgcagaaaat gaaatcacaa cctttcccgg
     8221 caaccttaag gaactagcga ccaaatatac caacttatgt cgatgccata agagtatcct
     8281 gattaatccc gcacatgttt tgcgtctgga catcacaaac cgattcgttt atatggacaa
     8341 tcaagataaa cttgaggtca gtattcggag aataggcgag ttgcgcaaca tcttaacagg
     8401 cacacgggct ttatcttaag aagagtgtga ctgggcaatc atcctagatt tctgttaatc
     8461 aacacagctg aacgcacaaa taacgcatcc tcaatatcaa gggtgcgtta tttggttggt
     8521 ttatacaggt tggaaatact attcctcctg aaaggtttta tgccaatctg tcatcggttc
     8581 tacttcaacc aaagcgctat cgactgaccc attcgataac cagcgtcata tatccctttt
     8641 aaaattcccg gtgaaaagta ccaaaacgcc attattaaaa ccccaatggc gacaagcaac
     8701 gacactttct gttggaatga taatcttgca aattgatcga ttacgctcac ctcgtttaca
     8761 aacagactta tttttacttc tttcagcaat ccattagtaa catgttcttt atgttctccc
     8821 accttctaat aaaaaggcaa tatactaatg gccaactgcg tcaattggga acatttctcc
     8881 caaaaagatg ttcgcgcatg aagccgatgt cttaagaggt ctatcatctg ccagctgatc
     8941 gcagttacaa atacgaatgt gaagaaaaat gccagaatca aaagcataga atataacaca
     9001 actgtcataa gcaaagctcc ttgagtcttc ctttaaactt acattgaggc ggcaaattag
     9061 cgagcacagg ttcggagata ccatacgttc tgctaaggtc ggtcatacaa gcaagaaatc
     9121 acaaaaatga caccatttta gctatttaat gctatttccg aaaggccttt tgctgtcagg
     9181 aagaaaaaac aatcgtgggt tttgaaagct catcttattt agtatctgtt ctgccatact
     9241 cacgcgcaag atctcctgat ttgtattttt gtttcaatac aaatcaggag acttttgcgg
     9301 tttttggctg atagaacaca gggtaacaag attctgacac taaaagcagt tcccaaatat
     9361 cagtagtgtc ccctaaaatc tcatttgccg tcatgaacag ccgatattgc attattatgg
     9421 cctggcagat agctgtgtca caatagttgc tgtctctcgg tgctgacagg cttcccactg
     9481 acaatgacgc tgccgcctta ccaatacttc gaaatcaaac aaagaaaatt tgttatttag
     9541 agcgtttatg atctttaacc cttgaagatg cgacactcat tttagaaaaa agaatcaaaa
     9601 caatgaagat tgaaagcatc tcaatgaacg cccggacgat gaaaaaatca aaacccaagc
     9661 aatcgacaat cagcttgttt aagctatcac tgagcgaaaa cccgccgaaa aagatacata
     9721 cgataatcca gaaagaagct tcattaagcc atgtgtgcat agttttaaga atcgtcatcg
     9781 tacctccgct ttgctcatca ctaaatcatt tatcgaccga tcagttttgg ctctgtcttt
     9841 ttaagttaga ccgttatatt cgaaactagt ttgcctaagt cgccgttata aattggacaa
     9901 ccttttaggc atcatccatt gacaacaagc ccataccaac cagcatcgca atcggagttt
     9961 gatctgcacc aaatgaatca gtgaagctaa ccataatcaa gcgcgctcac cgttttagta
    10021 gtggcttcta gtacccatat ctgatattcg ccagcgaaga aagctgctcg aatttatcag
    10081 attgttgctt ggttaacaaa atattgtttt gcaacagggc attagagatt tctagattca
    10141 tacggcttaa aataaatgga accgctgctt gcttatgaat taaggcttct ttattgttcc
    10201 ttaacactgt ccgtatgcga tcactacgga aagaactgtc atcgaaatcg tgaagcagct
    10261 catcgataag ctgtatcgct tgttcagccc gttcattccc gccagcaaac catttcaatt
    10321 tgttcatcat tcactccaaa aaacgttgtg cttgtgcatc ttcacttgta acacgtttgg
    10381 caccgtgcat tgccagatct gccgtagcaa taacggtaag tgcatgctcg cccacagata
    10441 aaaacttgtt ctgggaagag atacttttac aacggcgaaa tcgctaaaaa tcaacgcacc
    10501 gttattacga tcgttcccat ccttgcttga ccccagctac cagctcatca gcatggttcc
    10561 acgcatctgt tgccaggaat ccaagaatag cagcgacagg gattgcgagc ggtccgatac
    10621 cgccggaaat cttactcaat tcagcttcat tcaacttagt cattaaaatt acctccttgt
    10681 atttgtaaga aactactcgc cagttgatcc aaaagtcttt gttatggata ttgtggcgat
    10741 aaaatgctca tctaccgcac aactttttgc aaatacaacc atggagtcat cagcggcatg
    10801 cctggattaa agccacttga ccttcaccat cgaaattctg ccacttggtt tgtatggcag
    10861 cattacagcg tacggcctag gcattgaacg gaacactcaa agtttaagcg taggtaataa
    10921 accagatggc attcaaaata taagcacgtt taaaggctat ctgatgctca ctgtcgagat
    10981 atttatcatt ccaaacgcga tagtgaccat cttttttaca gcacgtatat accaaaacac
    11041 ctaatagata taccaagata aacgtagcta acattaaaag atttatctta ttcatacgtt
    11101 cgcccgttcg agtgcctatt catcccggat actaattgcc gttaagttta tcaacaatct
    11161 ctttggcagg accaatggct ggtgcaaaca tggcgccttc agcccaagaa cgcgcggttg
    11221 aaccaatggc cttcccgata aaggtccaca gattaccatt atcgccacca gaaatacttg
    11281 ccaaatcagc cgtgtttaaa gtttttaaat gatccatgtt cttcctcctt tttcctttat
    11341 gagcctttca atctatctat cagcctaaat tatcacttaa gtcgccacct taattggatg
    11401 aacaatcggc agtttatact taaatgccga ttcgtaagct ggcggatggc gttcgtttgg
    11461 tggatccaca ctgcaattgg ataaaggaac attcccaccg ctcgtcaatt caagcatttt
    11521 tcccgagatt tccttcaaag ctagtcctgt tcgcatggtc atcccatttt cctcctttcc
    11581 ctttgttaga aggacttccc ttcttcccca tcaatataaa gtagacagcc aggtttgtgg
    11641 gaatgaattt tttaacgtcg atttttgcaa gaaaatcgtc gtaaaaaacc taattttgac
    11701 gtttatcgtt aaaaacccgg cgattatttg atattgccgc cttctcttca aaactcaagc
    11761 aactgcaact gtatttactt ttacccatgt ctttttcgcc actgtgagca tccagtctta
    11821 agccaactta gaaaggcgat taggctcgcg gccagcatgt gcatccattc gccggggaaa
    11881 tgatgacaaa ctgcacacat ataaccgaca ataaatgtta ataagcagcg ccaaaatctt
    11941 ttttgattca cgcgctcttc tgcttttcct cccgctcgct taacagcatt aacaacgtca
    12001 tcaaaatcaa cattggcgtc acaaaactgc cgtgattggt ccatccaaat gccgatgtga
    12061 ccgtataaat ggcgaaaata atggtagcga ttatcaaccc ataatcgact agtttagtca
    12121 gtcgcgtaga catcgttttt ctccttaaac tcgttctatc ataattgata catacagcca
    12181 gtttacgaat gcgacaatcg tgccagaaac ttttcattgt tttggccacg gcgaaaaagt
    12241 cgcagtgcaa tcgctaggta aatcccggca ataaggaatg cgtgaacaat cgtcatcgtt
    12301 atagcgttgg gatcactagg cgcttctttc ggatacggtc cactaaccaa agtgataaca
    12361 aaatcaatca aaaagtggat caatattggc ataagcaacg atccgtaacg aatataaagt
    12421 gctgcaaaaa tagcccccat gccaaatgcc tggatcactt gggcaattgt tatcacaagc
    12481 ccttgagcag gcaaattact caggtgagcc aatgaaaaaa caagactgct taaccctatg
    12541 caaactaaga gttggtattt ggcgtggcga tgatgggcaa cataaaacgc ccgaatcaac
    12601 tcgccaagca tgacgccacg aaacaaatac tcttcgggaa cagcggcaat agtaccaatc
    12661 acagctgctt gcaagacgtc aatcggtgtt cgatttgtaa ccgtgaacca agcgataagc
    12721 atcaagacca gtccccaaat gataactggc ttcaatcgtg gtcgactaag tgtcactttt
    12781 aagacgataa cttgtttcag taacagccaa ttaagtgcga tcatcaccag taaaatgatg
    12841 gctttaaata agatattccc agcccagaag tccaatttaa gcatgtaaac tgctggaatt
    12901 aaaagcagct ggctgattag cacaaccaaa agcaagatat ataaaacgca aaatcctggc
    12961 gacaatagca aatgacgttt tctttccatt tatccacctt cactcacacg tttcaatgca
    13021 acgcagcttc gatatcgcta cccacaatat accgaggctg cgcatgttac ggatcattaa
    13081 cttttaaacg tcgggttttc gccgataatc gttgtgtttt gaaacttgac aacacgttaa
    13141 tcgtctccat ttccaaaaag gtaggccaat gaagacgcac ttacttccca tttactgact
    13201 gccccacagt tgcacgatcc tgaaaatgcc gtaagcaaaa tcgcctcatc caataccaac
    13261 gcgccaacgt tagtcttgaa tgaggcgatg aaaagttaga gttcgatatt tacgcttctg
    13321 cggcttcagc caaatcagca atgctcgtct gctttagcac ttgcaccata gcatcttcgg
    13381 ctcggtttag aacgttggtg cttgctacta accaacttgt gacgcgctcg ccgttgacaa
    13441 acgcagctgg atcgatttcc tgatgcagct taaataacgg tgccgtccct tcaatagccg
    13501 ctaagatttc gtaaactgta atcgtttgtg gcgttttggc taatcgcaaa ccgccattga
    13561 gaccggtttt cgacgttaaa ataccacttt ttttaagtgt agacgaaatt tttttaatgc
    13621 taggaaccgg aatgtttagc atttcggaaa tcttttgaat tgataaatag tcttcgtgtt
    13681 gtgcttggga ctttgcgttg acataagccg taatttcaag tgcttgcgag aatgcgactg
    13741 aaaaagccat cgaatatacc tcccattagg cgattgtgta tattctatta taccaatgat
    13801 atcgttactt ggcggctttt tctgccggaa taatgagcgt gacgacaagt attaagccaa
    13861 caatggtcat gccaacgcca atcaacattg cctgtccgaa tacatcggca attttagata
    13921 agctggcggt cgaggccgca aaaattgcca gtcctagagc gccgccaaat tgtcgggcag
    13981 tgttgtagac gcctgatgca gcccccgaaa tttccggccg aattctagcc aaacccgaag
    14041 tagcgagtgt ggcaaatgcc agcgcgaatc ctaccgcaaa tccgagtgtt ccgagtaaca
    14101 aaaaccagta attggcaaac cgtgatgcca ctgccagttc agccaatgaa agtagcaccg
    14161 tgacaaatcc gaagatcatg acccttgagt tacgccaccg atcaacgaag gtccgggcct
    14221 tgactgccac aatgaagagt aagatggcca ttggcaccat gcctaacgca gtcataaatg
    14281 gcgttaatcc taagacacct tgcataaact gaggtgtgta gaaccaaaag ccgattgcag
    14341 cggcactaaa caacaaagaa ctgacataag aagccatccg ttccctatcc gtaaagattt
    14401 ccagtggcat tgtcgggtgg gcaacgcgac cttgactagc aatgaacgca atccaaagaa
    14461 ctgctgaaat cagtaatgtg gggattggcc atggactgcc atccaaccca tatgagattg
    14521 aagtcatcgc taatactgac aagatcgtac caatccagtc aatctttccg gtttggcgtt
    14581 ttgcactagg taaatatcta gccgcaatac caaccatgat taatgcgatc ggaccattca
    14641 tgtagaaacc gacccgccat gacgcaaacg ttgcaaagaa gccgccaatg actaaaccaa
    14701 ccgctgcacc ggctccaatc acagaggcgt agtagccaat tgcccgctgc cgtgcttttc
    14761 cttgaaaggt gtcagttaac aatgctaaac agttcggtgc aagaatggcc gcgcccacgc
    14821 cttgaacagc gcgaaagcta atcatgacaa gcgcattggt agctgccccg actgccagac
    14881 tgccaactcc gaaaatagct aaactcgcaa tgaataatgg tttgcgtccg taaatatcgc
    14941 ctaatttacc gcctactagc atcagcccag cataagttag cgcataggcc acctgcaccc
    15001 aagacaacgc gccagcattc aaatgcaatt gtgccgccat tttaacggta cccgtgtaaa
    15061 caatcgatgt gtcaagcaca cctagaaaag ccccaatcag tgccagccct aaaataatga
    15121 cttgagtcgc tgacatgcgc tgcgattggg tgattgccgc atctgtttcc tcaatgacgg
    15181 tgtcgtcagc caggccgtca ttgattaatt ccttgtcttc ttctttgctc atatgagatg
    15241 cccctttcta tggttcactt agtatattcc gtttatacta ttatggcaaa tcttttttga
    15301 gcaaaaaaac cacgtgttcc ttaattctat ggaaacacgc ggctacaagc gaattctatt
    15361 cgggccggtt actggaatca gaccatggct tgggcaacaa ctgtctaaat aataaagtgc
    15421 ggcccgccta cctgactcaa ctcgccatga atgtcatttt ccataaagtc ttttaccgcc
    15481 tgccaccact gattggcctc cgctgaaagt ttcattcctt gcaagccgat taatcgcgta
    15541 aaccgtgcgt atagtcgcga caaggcgtaa tctgcggctc gattcttgag cacattaggc
    15601 cgctttaaaa tagctaaggc ctcatccaca acttcccgtg cttctgtctc catcaggcca
    15661 ccactagccg cttttttcag actcaggttt aatccggtca aaataaacag aatctgattt
    15721 ctttgcacca tattcatgag cgctcctcca tgtctggtag ataagtgttt gcattgagat
    15781 agcgttttct tgaattgcta actgcaatat accaaattta tcaagcttca ggtcaaactt
    15841 tcgataaacg tcgccttttc gccgattaac gttattgcgg acatgaatcg cccggtccaa
    15901 agcgcataga aaaagccgtg gtgcattaac cacgactaat cggaagcgcg tatttcagca
    15961 tagtcgtaaa aaggctgaaa tgacacagtt catcagcatc gaacaagctc atattccatc
    16021 cggctactta atgtccgcca ccccagacaa ttggaaaagc gactagccca gcagccagcg
    16081 cctgatcgcg ataacgcttg gcattgacct gatctgccgg cacatccgcc ttgatcgcat
    16141 tgaaaatggc gatcatctcg gctggaatcg cgtgatgaat gagataatac ttggaaatat
    16201 catgcgatag ctgggtcacg actgcgacat aggctgtttt gtcctctgca tcttccagtt
    16261 gtttcgcgtt ggattcgatt atttgcttta atttggcatc agctttcacg gccggac
//
