LOCUS       gnlProkkaIPENCJMP_4     2449 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IPENCJMP_4.
ACCESSION   gnlProkkaIPENCJMP_4
VERSION     gnlProkkaIPENCJMP_4
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 04:09:13
            Original ID  :: gnl|Prokka|IPENCJMP_4
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2449
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2449
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:2447]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..2447
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..2449
                     /SMILES="NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2449
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             3..2447
                     /NRPS_PKS="Domain: AMP-binding (2-363). E-value: 7.9e-95.
                     Score: 309.7. Matches aSDomain:
                     nrpspksdomains_ctg4_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (465-533). E-value: 1.2e-25. Score:
                     81.4. Matches aSDomain: nrpspksdomains_ctg4_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (548-814). E-value:
                     2.4e-95. Score: 310.8. Matches aSDomain:
                     nrpspksdomains_ctg4_1_Condensation_LCL.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     325.6; E-value: 7.6e-99)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="AMP-binding (E-value: 2.4e-110, bitscore:
                     355.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.2e-18, bitscore:
                     51.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 6.8e-85, bitscore:
                     270.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKESMVGVLAERSPEMAVSVLAVLKAGGAYVPLDPEYPEDRLRYM
                     LEDSGACLLLAQPGLSVSGFSGETLEVSLSSLTNETETGAVSEEADADSLAYIIYTSGS
                     TGTPKGVAVEHRQAAAFLSGMQGQFPLTEEDIIVLKSSFSFDASIWQLFWWTMSGASVY
                     LLPAGWEKDPVRMIEAFASEKVTTAHFIPAMVNSFLDALETEPAETRTRLGRTLTRVFA
                     GGEALSPLTAARFADLLPETMLIHGYGPTEATVDAAFYVCDRKRDSGRTRLPIGKPVPG
                     ARLYVLDSGGTIQPAGVAGELYIAGTGVARGYLNRPELTEERFVVDPFYPGERMYQTGD
                     IARWTEDGLVEWLGRSDGQVKVRGYRIEPGEIEAAIRHIDGIREAAVTARTEHGETALY
                     AYIEGRKSDDVRAELATRLPAYMMPAQFIEMSEWPVTPSGKLDRRALPAPGGSADRQAY
                     TAPRNVTEMKLCALWEEVLKNGPVGIRDHFFERGGHSLKATALVSRIAKEFGVQVPLQD
                     IFARPTVEELASVIQDLEESSYEAIQPAQTQDTYPVSSAQKRMYVLQQLEDGGVGYNMP
                     AVLELTGPLDRVRLEETFRQLVERHESLRTSFETGPDGEPVQRIHDSVPFQLDEAESAD
                     AFVRPFCLEEAPLFRAALVKESEEHHLLLTDMHHIISDGVSVNTLIKEFGELYAGRSLA
                     PMRLQYKDYAVWQRSFQEKEGYQKQEAYWLKRLEGELPVLELPADKPRPAVRSFAGGSV
                     SCTLDADTASGLHRIARDHGSTLYMVLLAAYNTLLARLSGQEDIIVGSPIAGRPHKDLE
                     PIL"
     aSDomain        9..1091
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_1_AMP-binding.1"
                     /evalue="7.90E-95"
                     /label="ctg4_1_AMP-binding.1"
                     /locus_tag="ctg4_1"
                     /protein_end="363"
                     /protein_start="2"
                     /score="309.7"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="ESMVGVLAERSPEMAVSVLAVLKAGGAYVPLDPEYPEDRLRYMLE
                     DSGACLLLAQPGLSVSGFSGETLEVSLSSLTNETETGAVSEEADADSLAYIIYTSGSTG
                     TPKGVAVEHRQAAAFLSGMQGQFPLTEEDIIVLKSSFSFDASIWQLFWWTMSGASVYLL
                     PAGWEKDPVRMIEAFASEKVTTAHFIPAMVNSFLDALETEPAETRTRLGRTLTRVFAGG
                     EALSPLTAARFADLLPETMLIHGYGPTEATVDAAFYVCDRKRDSGRTRLPIGKPVPGAR
                     LYVLDSGGTIQPAGVAGELYIAGTGVARGYLNRPELTEERFVVDPFYPGERMYQTGDIA
                     RWTEDGLVEWLGRSDGQVKVR"
     aSModule        9..1601
                     /complete
                     /domains="nrpspksdomains_ctg4_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg4_1_PCP.1"
                     /locus_tags="ctg4_1"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       63..104
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0001"
                     /evalue="1.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg4_1"
                     /protein_end="34"
                     /protein_start="20"
                     /score="21.1"
                     /tool="antismash"
                     /translation="LAVLKAGGAYVPLD"
     CDS_motif       288..347
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0002"
                     /evalue="4.10E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_1"
                     /protein_end="115"
                     /protein_start="95"
                     /score="34.6"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGTPKGVAVEH"
     CDS_motif       858..899
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0003"
                     /evalue="3.60E+00"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_1"
                     /protein_end="299"
                     /protein_start="285"
                     /score="1.4"
                     /tool="antismash"
                     /translation="VLDSGGTIQPAGVA"
     CDS_motif       885..974
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0004"
                     /evalue="3.10E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg4_1"
                     /protein_end="324"
                     /protein_start="294"
                     /score="57.8"
                     /tool="antismash"
                     /translation="PAGVAGELYIAGTGVARGYLNRPELTEERF"
     CDS_motif       1056..1121
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0005"
                     /evalue="1.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg4_1"
                     /protein_end="373"
                     /protein_start="351"
                     /score="36.6"
                     /tool="antismash"
                     /translation="WLGRSDGQVKVRGYRIEPGEIE"
     aSDomain        1398..1601
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_1_PCP.1"
                     /evalue="1.20E-25"
                     /label="ctg4_1_PCP.1"
                     /locus_tag="ctg4_1"
                     /protein_end="533"
                     /protein_start="465"
                     /score="81.4"
                     /tool="antismash"
                     /translation="EMKLCALWEEVLKNGPVGIRDHFFERGGHSLKATALVSRIAKEFG
                     VQVPLQDIFARPTVEELASVIQD"
     aSDomain        1647..2444
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.40E-95"
                     /label="ctg4_1_Condensation_LCL.1"
                     /locus_tag="ctg4_1"
                     /protein_end="814"
                     /protein_start="548"
                     /score="310.8"
                     /tool="antismash"
                     /translation="DTYPVSSAQKRMYVLQQLEDGGVGYNMPAVLELTGPLDRVRLEET
                     FRQLVERHESLRTSFETGPDGEPVQRIHDSVPFQLDEAESADAFVRPFCLEEAPLFRAA
                     LVKESEEHHLLLTDMHHIISDGVSVNTLIKEFGELYAGRSLAPMRLQYKDYAVWQRSFQ
                     EKEGYQKQEAYWLKRLEGELPVLELPADKPRPAVRSFAGGSVSCTLDADTASGLHRIAR
                     DHGSTLYMVLLAAYNTLLARLSGQEDIIVGSPIAGRPHKDLEPI"
     CDS_motif       1719..1826
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0006"
                     /evalue="1.80E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg4_1"
                     /protein_end="608"
                     /protein_start="572"
                     /score="58.9"
                     /tool="antismash"
                     /translation="YNMPAVLELTGPLDRVRLEETFRQLVERHESLRTSF"
     CDS_motif       2001..2066
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0007"
                     /evalue="7.00E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg4_1"
                     /protein_end="688"
                     /protein_start="666"
                     /score="28.2"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNTLIKEFGELY"
     CDS_motif       2097..2129
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0008"
                     /evalue="1.60E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg4_1"
                     /protein_end="709"
                     /protein_start="698"
                     /score="17.4"
                     /tool="antismash"
                     /translation="QYKDYAVWQRS"
     CDS_motif       2388..2444
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0009"
                     /evalue="8.90E-07"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg4_1"
                     /protein_end="814"
                     /protein_start="795"
                     /score="21.4"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHKDLEPI"
ORIGIN
        1 tccgcaaaga aagcatggtc ggcgtactcg ctgaacgctc gccggagatg gcggtttcag
       61 tgcttgccgt gttaaaagcg ggcggcgcct acgtgccgct tgacccggag tatcctgagg
      121 acaggctgcg atatatgctt gaggacagcg gcgcttgtct cctgcttgca cagccggggt
      181 tatccgtttc cggtttttcc ggtgaaacgc tagaagtgtc tctttcttct ctgacaaatg
      241 agacggagac aggggctgtc tctgaagaag cggatgctga ttcgctcgct tatatcattt
      301 atacgtccgg ttcgacggga acaccgaagg gagtggctgt tgaacaccgt caagccgccg
      361 cctttttatc agggatgcaa gggcagtttc cgttaacgga agaggatatt atcgtgctga
      421 aatcatcctt ttcattcgac gcctccatct ggcaattgtt ttggtggacg atgtccggcg
      481 cctccgtgta tctgcttccg gccggctggg agaaagatcc tgtgcggatg attgaagcgt
      541 ttgcctcaga aaaggtgacg accgcgcatt ttattccggc gatggtcaac agctttttag
      601 acgcgctgga aacagagcct gcggaaacaa gaacacgcct cggcagaaca ctgacacgcg
      661 tgttcgccgg aggggaagct ctttccccgc ttacggctgc ccggtttgcc gatcttctgc
      721 cggagaccat gcttattcac ggctatggac cgacggaagc gacggttgat gcggcgtttt
      781 acgtctgtga ccgaaaacgg gacagcggac ggacaaggct tccgatcgga aaacccgttc
      841 cgggtgcccg tctgtatgta ttagatagcg gaggaaccat ccagcctgcg ggcgtggcag
      901 gagagctgta catcgcgggg accggcgtgg cccggggcta tctgaaccgc cctgagctga
      961 cggaggagcg ctttgtcgtt gatccgtttt atccgggaga acgcatgtat cagacgggcg
     1021 atatcgcacg ctggacagaa gacggccttg tcgaatggct cggtcgttca gacggacagg
     1081 tgaaagtccg cggctaccgg attgaaccgg gggaaatcga agcggcgatc cggcacatcg
     1141 acggcattcg tgaggcggcg gtcaccgccc ggaccgaaca cggcgaaacc gcgctttacg
     1201 cctatattga aggacgaaaa agcgatgacg tgcgggcgga gcttgcgaca cgccttccgg
     1261 cctacatgat gccggctcag tttatagaga tgagcgaatg gccggtcacg ccaagcggaa
     1321 agcttgaccg ccgcgcgctg ccggctcccg gcggatcggc agacagacag gcgtacactg
     1381 ccccgcggaa cgtcacggaa atgaagcttt gcgccctttg ggaagaggtg ctgaaaaacg
     1441 gccccgtcgg catccgggat cacttttttg agcggggcgg ccattcgtta aaagcgacgg
     1501 ctctcgtctc ccgcatcgcc aaagagttcg gtgttcaggt gccgttacag gacatcttcg
     1561 cccggccgac ggtggaagag ctcgcttcgg ttattcagga cttggaagaa agctcgtatg
     1621 aagcgattca gcctgcgcaa acacaagata cctacccggt gtcttcagcg cagaaacgga
     1681 tgtatgtgct ccaacagctt gaagacggcg gtgtcggcta caatatgccg gctgtgctgg
     1741 aactgacggg cccgcttgac cgtgtccggc tggaggagac gttccggcag cttgtggagc
     1801 ggcacgagtc gctcagaacg tcctttgaaa cggggcctga cggcgaaccg gtgcagcgca
     1861 tccatgacag cgtgccgttt cagctcgatg aggccgagtc agctgacgca ttcgtccggc
     1921 cgttttgtct ggaggaagcg ccgctcttcc gtgcggccct cgtgaaagaa tcggaagaac
     1981 accatctttt attaacggat atgcatcata ttatttctga cggtgtgtcc gtcaacacct
     2041 tgataaaaga attcggcgag ctgtacgcag gccgttcgct tgcgccgatg cgccttcaat
     2101 ataaagacta tgccgtctgg cagcggtcgt ttcaggagaa agaaggatat cagaagcagg
     2161 aagcctattg gctgaagcgg cttgaaggag agcttccggt gcttgaactt ccggctgaca
     2221 agccccgtcc ggcggtcaga agctttgcgg gcggcagcgt atcgtgcacg cttgacgctg
     2281 acacggcatc cggccttcac cgcatcgccc gggatcacgg ctccactttg tatatggtgc
     2341 ttctcgccgc gtacaatacg ctgctcgcgc gattgagcgg gcaggaagac atcatcgtcg
     2401 gatcgccgat tgccgggcgc ccgcacaaag accttgaacc gattctcgg
//
