LOCUS       c00072_gnlPro..        16052 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DLJAOKGB_80.
ACCESSION   c00072_gnlPro..
VERSION     c00072_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 05:23:08
            Original ID  :: gnl|Prokka|DLJAOKGB_80
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16052
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16052
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[193:6052]"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      194..6052
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
     cand_cluster    1..16052
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /kind="single"
                     /product="Nitrate_reductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16052
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Nitrate_reductase"
                     /region_number="1"
                     /rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /tool="gutsmash"
     CDS             complement(194..883)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_gam"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg72_1"
                     /sec_met_domain="Nitrate_red_gam (E-value: 1.6e-77,
                     bitscore: 250.6, seeds: 140, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSGWSIFLWVIYPYIMLASFFIGTFVRFKYFHPSITAKSSELFE
                     KKWLMIGSVTFHIGIILAFFGHFLGMFIPASWTAYFGITEHMYHIFGSLMMGIPAGILA
                     FVGIAILTYRRMTCSRVYKTSDINDIIVDWALLITIALGLASTITGAFIDYNYRTTISP
                     WARSLFVLNPQWQLMRSVPLIYKIHVLCGLAIFGYFPYTRLVHALTLPWQYIFRRFIVY
                     RRRARVY"
     CDS             complement(876..1454)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_del"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg72_2"
                     /sec_met_domain="Nitrate_red_del (E-value: 5.5e-10,
                     bitscore: 30.1, seeds: 108, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIDFRRLIDLKDTFAILSRLIDYPETETFSPEIRQLLLTDNALST
                     ATRGELLSLFDELAALSPIEVQEMYARLFEMNRRYTLYMSYYKMTDSRERGTILARLKM
                     LYEMFGISEATSELSDYLPLLLEFLAYGDYTNDPRRQDIQLALSVIEDGTYTLLKNAVI
                     DSDSPYIQLIRLTRSLIGSCIKMEVQEDA"
     CDS             complement(1447..3006)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitr_red_bet_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Fer4_11"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg72_3"
                     /sec_met_domain="Fer4_11 (E-value: 4.9e-39, bitscore:
                     123.3, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00077, bitscore: 10.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Nitr_red_bet_C (E-value: 2.4e-28,
                     bitscore: 88.4, seeds: 110, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIKAQISMVLNLDKCIGCHTCSVTCKNTWTNRPGAEYMWFNNVE
                     TKPGVGYPKRWEDEDQYHGGWTLNSKGKLKLRAGSKLNKIALGKIFYNNDMPELDNYYE
                     PWTYDYKTLFGPEQKHQPVARPKSQITGEGMELTTGPNWDDDLAGSTEYVQQDPNMQKI
                     EGDIKNNFEQAFMMYLPRLCEHCLNAPCVASCPSGAMYKRDEDGIVLVDQERCRGWRFC
                     MTGCPYKKVYFNWKTHKAEKCTFCYPRIEEGQPTVCAETCVGRIRYIGAILYDADRVEE
                     AASTPDESKLYEAQLGLFLDPNDPEVVKQALKDGISEEMIEAAQKSPIYKMAVKEKIAF
                     PLHPEYRTMPMVWYIPPLSPVMSYFEGRDSIKNPEMIFPGIDQMRVPVQYLASLLTAGN
                     VPVIKKALYKLAMMRLYMRAKTSGRDFDSSKLERVDLTEERATSLYRLLAIAKYEDRFV
                     IPSSQKAEMEDAQTEQGSLGYDECEGCALAPQHKSMFKKAEAGKSTNQIYADSFYGGIW
                     RD"
     CDS             complement(2996..6052)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molydop_binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molybdopterin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg72_4"
                     /sec_met_domain="Molybdopterin (E-value: 1.2e-118,
                     bitscore: 387.4, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 9.7e-24,
                     bitscore: 74.3, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGEQMSFYDWYADLPPASPQVWGEQTDVPESAEWYNSSYIIMWG
                     SNVPLTRTPDAHFMTEVRYKGTKIVVVSPDYAENVKFADDWLAPEPGSDSGVAQAMTYV
                     ILDEFYQKHPVKRFIDYSKRFTDLPFMVELEPSTANDDHYTPGRFVRISDLVDDDTIVN
                     PAWKTVVYDQNNHKIVVPNGTMGQEYNAKEKWNLELLDQNGNKIDPALSINDQGEETEQ
                     IIADFPAFSNDGNSVVQRHLPVKKLKFTDGQEHLVTNVYDLMMAQMGINRTGNDELAAK
                     DAMDAESYFTPAWQESRSGVKAEQVIQIAREFAQNAAENEGRSMVIMGGGVNHWFNADM
                     NYRNIINMLMLCGCVGMTGGGWAHYVGQEKLRPQEGWANITFANDWEKGGARQMQGTTW
                     YYFATDQWRYEEIDNQAQKSPVWKSKHSYLHNADYNQMAIRLGWLPSYPQFDRNPLSFA
                     KDYNTTDINEISKKVVDELKKGSLHFAAEDPDANQNQPKAFFLWRSNLFASSGKGAEYF
                     MKHLLGAENGLLAKPNDRVKPQDMIWRDKGAIGKLDLVVDMDFRMVSTPMYSDVVLPAA
                     TWYEKKDLSSTDMHPFIHPFNAAVSPMWESKSDWQQFKLLAKTVSEMAKKYMPGTFYDL
                     KSAPLGHNTQGEIAQPYGEIKDWKNGETEPIPGKTMPSLKLVTRDYTKIYDKYITLGPN
                     IVNNYNYKVDDQYDYLKDMNGIASEGIGAGCPLLDEDEKVCDAILRMSTASNGKLADRA
                     WEKKQERTGEHLTDIGRGHADDSMSFKQITAQPQEAYPTPIGTSAKHGGARYTPFSLMT
                     ERNIPTFTLTGRQHFYIDHEIFREFGENMATYKPSLPPVVMAPGDVDVPPVKDEVTLKY
                     MTPHGKWNIHTMYYDNLEMLTLFRGGPTIWISPQDADKIKVKDNDWIEVYNRNGVVTAR
                     AVVSVRMPEGSMYMYHAQDNEIYEPLSTITGNRGGSHNAPTQIHIKPTHMVGGYSQLSY
                     GWNYYGPTGNQRDLYANVRKLKKVNWSED"
     CDS             complement(6280..6624)
                     /locus_tag="ctg72_5"
                     /transl_table=11
                     /translation="MEPLHNLKKIVVVGKSFIVSDGRMTKLSEQLMESTVQAHVLGMFM
                     SSKELLLGNIKLQIIHHADLIFQDMNHGDVHGELVSLGMNIVPFELSTHIFVVNYGSFG
                     LLPRKNMKIP"
     CDS             6807..7826
                     /locus_tag="ctg72_6"
                     /transl_table=11
                     /translation="MNRYDRQERVHQIGVVGQQKISHATIMIVGVGALGSYTAEQLVRA
                     GVKRLVLIDPDTVDVTNLQRQSLFTEADANQQRLKVEAANEHLHEINSACQITAIPAPI
                     TADLIDEYQFTLCLDCLDNYQARDLLNKLAIIKNFDYLFASCAGTYGNVMAISPQNHPC
                     LNCLFPNINELKQNDCDLIGVNTALIPIVAGLQVSLALHYLVDKTQVNFNELITVDNWS
                     MQFSKFAINKNCHCPACAKPSSISLEEESAPELHMLCGENAYYTVKEKPINFGRLKEFL
                     AKKELLINANRLFLHFKWENRPVSIFKNGKIVMYDLPTSAIAQKQFESLNTLMKEDLL"
     CDS             7823..8320
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg72_7"
                     /sec_met_domain="MoCF_biosynth (E-value: 1.2e-33, bitscore:
                     106.4, seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIAILTVSDSRTLDSDTSGKLIAMKMANAGLSVVDRVIVNDDI
                     VNIQTAYLQLEQQAIDIIITNGGTGVAQRDVTIPAIRPLLKRLIPGFGEAFRQISFDEI
                     GTRALASQALAGFNYRNQLTYCLPGSHNACQTALSKLILPEYEHLLFESSSQRKEVHHH
                     AH"
     CDS             8310..9527
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg72_8"
                     /sec_met_domain="MoCF_biosynth (E-value: 4.6e-23, bitscore:
                     72.2, seeds: 114, tool: rule-based-clusters)"
                     /sec_met_domain="MoeA_C (E-value: 1.5e-13, bitscore: 41.5,
                     seeds: 41, tool: rule-based-clusters)"
                     /sec_met_domain="MoeA_N (E-value: 1.2e-39, bitscore: 126.2,
                     seeds: 1302, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTRRTPISVAEAQKKINEIPLKTTTETIPLSEANHRILAEDVHA
                     HYDYPHFRRAGMDGYAILASDDHDFPREFNVRGEIQAGATWDQPLQPGDAVRIMTGAYV
                     PSDAGKVIRIEKTRPAEDKNKVQIITTESKTNITETGTDVKSGDIVLAKDQEINPGGLA
                     VLTAFGVQEVTVYKKPRIAIIATGTELLGPNETIEQGKIFNSNGIMLKNLVEETGGIVD
                     FETQLPDDANLIKQTLEEQIATHEIVITDGGVSVGDFDFIGDEARKADELLFNKIKQRP
                     GSVTTAFVQNNTLVMALSGNPGACFTGFYLYMEPLIRRYQHQASRIKRVRAILAAPYNK
                     TNGFDRYLRCTYEFKDDQFYVYPNGINRSGSLANLQTTTCLALIPHSTTPMKVGTETDA
                     WLLPFK"
     CDS             9506..9994
                     /locus_tag="ctg72_9"
                     /transl_table=11
                     /translation="MAITLQIIGHKKSGKTLIMTALIERLSKEGYRVAALKHDAHNAAM
                     DVPTTDSARMSNAGANQVILQSATEFFFHQKSNVPTLTEMVELLSDDNDFVLIEGHKEA
                     NQYPQILLLKPGEDPTNIAPTTPLKTGSIFSGTNADLLGKNTIVNWCYNYLKQIKENT"
     CDS             9994..10566
                     /locus_tag="ctg72_10"
                     /transl_table=11
                     /translation="MIGLVYAGGKSIRFGKDKATYHVPRLPATNVQLAVEKLMPLCQQI
                     IVCANETNRAHIIELVGQVPAVQIICDIPPYDHHGPLSAIIACTSQFSVVQDYLTLAVD
                     YPYITKDVLAILARTSNSYIVTSQHSHYSLAHFSISNEQVTTWVDNNSDWRLRSFITNK
                     CGCHPLAYRSSAEFSNLNYREVDLNEK"
     CDS             10556..10840
                     /locus_tag="ctg72_11"
                     /transl_table=11
                     /translation="MKSKDSMTNPDFQKLISLVLNDLTIRRTMLENREQEVNQQMSSLE
                     KDAELEQLDDQIQQIQADFDHYREFQDPEFDFSATKYFQGPSMGLPRHP"
     CDS             10991..12046
                     /locus_tag="ctg72_12"
                     /transl_table=11
                     /translation="VLETANWIQKYFNQSPDAIFLFKNDDLLVSNEPAQRLVTMFNLDV
                     NYLLQIGKNAWSQLENDDCASCLIKKRLKGAAVPITFHSNATHPFHFSMVYRPLDDKEN
                     VFALTLENREQQQRLSQVEEQRILNQYVNEAHEKERQKISQDLHDSVAQGIYAAIMGIQ
                     RLATVQNQRNTEQFQSMSAAIEKQLQTTLKEIKELALDIRPSVLDNFGLIPAIKALAKR
                     LQNSTGITINVIALTSAENLQKNIQNVLYRITQEAINNAIKHAHSTEITIIVTNHNSYL
                     QLEILDNGIGFDLEQHSRFNGHSLGLMNMNERVKAYNGAFTITSKINKGTTVKVKFPYN
                     NLNKDTVRTNV"
     CDS             12039..12692
                     /locus_tag="ctg72_13"
                     /transl_table=11
                     /translation="MYNVLVADDHAIVRSGISYLVDLQPNFTVVDGTASGTDTYIRVEQ
                     GGIDILIMDLSMPPGENGLITTRRIHDKFPKVKIIILSMHEEQEYINKAMANGAMSYIL
                     KSSPDSEIVNALKHVINGEKYLDANIIVSKKDIKEINASGNTLKLKGYNGLSKREKEVF
                     PLIALGYSNKEISQKMFISTKTVEAHKANISRKLHLHGRVELVQYAIHHHLIDL"
     CDS             12788..13060
                     /locus_tag="ctg72_14"
                     /transl_table=11
                     /translation="MATNLSREDELRGILSDVARKHFTNSRQVNPVSNLFLTTKYAVEN
                     QYISGAVIDESFSSTLAEINLKNAVLTDRGRNKLAQLLTQSAKEN"
     CDS             13066..14034
                     /locus_tag="ctg72_15"
                     /transl_table=11
                     /translation="MDIQDKLKRDYENKSIYTAGFYADPDNDLANRKKLFDVLKSLVEN
                     QEATTPFALQIMLTNGEINVMPLGLVDLDELKKYENEQRSKHGLDEHNDDIPLLIQYAP
                     HAEKKEVVKKRIGTVQDLFTNFNEQIEKIWQTIKKFMQDNFALLTTIEKDLIADSQNVM
                     QEYRITFSKMTEAERKEKLGFSVPENEINQFCRYMADMHEVQAVVLSAGAFVNHELLGK
                     NSFTEMISDNIRRSTLFWVLDNTFYEIYYYFYMSNANDKLHKRLKHQRETFIVNMRNDA
                     FHRAQEFTEKQTKKVDFNEYFSDIFIPVAEQIIAEVNKFKD"
     CDS             14039..14944
                     /locus_tag="ctg72_16"
                     /transl_table=11
                     /translation="VNLTPDERLADALTTIIYQYPPMVREMININAGEKERLLRLSIFE
                     AFSHLSERDLTIDQITAAQLPELLALATHLNPPSFQPNNLTPGEFASQKAYSYVASYLM
                     NRFVHSLSTVGNPPQVLEELITDAGDVMLAQVRRLQFNYNQQFKVADYLADVKARWGLL
                     GAMTAKQSAVLSGAGNEIVSLAGQIGQAFGTASYITHEFQQLSNDPNLFIKMITAGQYP
                     LALLFARQQDPQWFNNFFSSNHRPSQEIFNQAYNLVLSRTDDVKQLITDIFSQLILDIE
                     VLPTGQTQDELLKLVEELKK"
ORIGIN
        1 cttgaacacc tacatcttaa ggcaaaagag gcctttttta tataattttt atcgcccacc
       61 cgcatagcag gtggtttttt gtttcgtgca ctcgctctgc tcgcgcactc aaccaggtct
      121 aaagacatta atataaaagc atcagaattc ctctgtgaag aaatctgatg cttttattat
      181 atcttcttat atattaataa actcttgcgc gtcgacgata aacaataaaa cgacggaaaa
      241 tatattgcca aggtagcgtt aaagcgtgaa ccaaccgggt gtatgggaag taaccaaaaa
      301 ttgctaatcc acagagaacg tgaattttat aaattaatgg cactgaacgc atcaattgcc
      361 attgaggatt aagaacaaag aggcttcttg cccatggact aatcgttgtt cgataattgt
      421 aatcgataaa tgcacccgta atagtacttg ctagacctaa tgcaattgta atcagtaaag
      481 cccagtcgac aataatatca ttgatatcac ttgtcttata aacacgagaa caagtcattc
      541 gtcgataagt aagaatcgca attcccacaa atgcaaggat ccctgctgga attcccatca
      601 tcaatgaccc aaagatgtgg tacatatgtt cagtgatccc aaaataagct gtccaacttg
      661 ctggaataaa cattcctaag aagtgaccaa agaaagctaa aataattcca atgtggaaag
      721 taacgcttcc gatcattagc catttctttt caaaaagttc gcttgatttg gcagtaattg
      781 agggatggaa atatttaaat ctaacaaatg ttccaatgaa aaatgatgcc aacattatat
      841 atggataaat aacccataag aaaattgacc agccactatg catcttcctg cacctccatt
      901 ttaatacacg aaccaattaa tgaacgtgta agcctgatta actgaatata gggactatca
      961 ctatctatca ctgcattttt taaaagggta taagttccat cttcaatcac acttaatgct
     1021 aattggatat cctgacgacg cggatcatta gtataatcgc catatgctag aaattctaac
     1081 aataaaggca aataatcaga aagttcacta gtcgcctctg atataccaaa catctcatat
     1141 agcattttca accgtgctaa aatggttcct cgttcacggg aatcagtcat cttgtagtat
     1201 gacatataaa gagtatagcg tcgattcatt tcaaaaaggc gagcgtacat ctcttgaact
     1261 tcgattggag ataatgcagc taattcatca aagaggctta ataattctcc ccgcgttgca
     1321 gttgataatg cgttatctgt aagtaataat tggcgaatct ctggtgaaaa tgtttccgtc
     1381 tcaggatagt caatcaagcg tgaaagaatg gcaaatgtat cttttaaatc tattaatcgt
     1441 ctaaaatcaa tcacgccaaa tccctccata gaaactatca gcataaatct gattagttga
     1501 tttgccagct tctgccttct taaacatact cttgtgttgg ggagctaatg cacagccttc
     1561 acattcatca tagccaagac taccttgttc agtttgtgca tcttccattt ctgccttttg
     1621 gctacttggg ataacaaagc ggtcttcata tttagcaatt gccagtaaac gataaagtga
     1681 tgttgcccgt tcttctgtta aatcaactcg ttctagttta ctgctatcaa aatcccgacc
     1741 actagtctta gcacgcatgt atagccgcat cattgcaagt ttatataagg ctttcttgat
     1801 gacaggaacg tttccagcag ttaatagact tgccaagtat tgaacaggca cccgcatttg
     1861 atcaattcct gggaagatca tttcaggatt ctttattgag tcccgtcctt caaagtaact
     1921 cataactggt gatagaggcg gaatatacca aaccattggc attgtccggt attctggatg
     1981 aagtgggaag gcaatctttt cttttactgc cattttatag atcggtgact tttgtgcagc
     2041 ttcaatcatc tcttcagaaa tgccatcctt gagtgcttgc ttgacaactt caggatcgtt
     2101 gggatcgagg aataagccaa gttgtgcttc atacagctta ctctcatcag gagttgatgc
     2161 tgcctcttct actcgatcag catcgtatag aatagcacca atatatcgaa ttcgaccgac
     2221 acaggtttcg gcgcaaactg ttggttgacc ttcttcaatt cgcggataac aaaaagtaca
     2281 tttttcagcc ttatgagtct tccagttaaa gtagaccttc ttatatggac atccagtcat
     2341 gcaaaaacgc catccccggc agcgttcttg gtctactaaa acaatcccat cttcatctcg
     2401 tttgtacatt gcgcctgatg gacaagaggc tacacaaggt gcattcaaac agtgctcaca
     2461 taatcgggga agatacatca taaatgcctg ctcaaagtta tttttgatat ccccttcaat
     2521 tttttgcatg ttaggatcct gttggacata ttcagttgat cccgctaagt catcatccca
     2581 gttaggacca gtggttaatt ccattccttc gccagtaatt tgcgacttag gacgagcaac
     2641 gggttggtgc ttttgttcag gaccaaataa tgtcttatag tcataggtcc atggttcgta
     2701 gtagttatct aactctggca tatcattatt gtaaaaaatc ttaccaagag cgattttatt
     2761 taatttgctt ccagcacgta attttaattt accttttgaa ttaagagtcc accctccatg
     2821 gtattgatct tcatcttccc agcgttttgg ataaccgaca cctggcttag tttcaacatt
     2881 attaaaccac atgtattcag cgcctggacg atttgtccat gtattcttac aagttactga
     2941 acaggtatga caaccaatac acttatcgag gtttaagacc atgctgattt gtgctttaat
     3001 cttcactcca gttcaccttc ttcaactttc ttacatttgc ataaagatca cgttggtttc
     3061 cagttggtcc atagtaattc caaccgtaac tcaattggct gtatcctcca accatgtgtg
     3121 ttggcttaat gtggatttgc gtcggtgcat tatgtgatcc cccacgatta ccggtaatgg
     3181 tagaaagagg ttcgtaaatt tcattatctt gggcatggta catgtacatt gacccctcag
     3241 gcatccgaac agaaacaacc gcccgcgcag taacaacccc attacggtta taaacttcga
     3301 tccagtcgtt atcttttacc ttaatcttat cggcatcttg gggactaatc caaatagttg
     3361 gaccaccccg gaataatgtc aacatttcaa ggttatcgta gtacatcgta tgaatattcc
     3421 atttaccatg aggagtcata tatttaagtg taacttcatc ttttactggt ggaacatcaa
     3481 catctcctgg ggccattaca actggtggta aggatggttt ataagttgcc atattttcac
     3541 caaattcacg gaaaatttca tgatcaatgt agaaatgctg acgacctgta agagtaaatg
     3601 taggaatatt tcgctcagtc attaatgaaa atggtgtgta gcgagctcca ccatgtttag
     3661 cagaagttcc gattggtgtt ggataagctt cttgtggttg agcagtgatt tgcttaaacg
     3721 acattgaatc atcagcatga ccgcgaccaa tatctgtcaa atgttcacca gtccgttctt
     3781 gcttcttttc ccaagctcga tcagcgagtt taccattgga agcagttgac atccgtaaga
     3841 ttgcatcaca tactttttcg tcttcatcaa gtaatggaca gcctgcacca atgccttcac
     3901 tagcaattcc attcatgtct ttgaggtaat catattgatc atcaacttta tagttataat
     3961 tatttactat attagggcca agagtgatgt atttgtcata gatcttagta taatcacggg
     4021 taactaattt taaagaaggc atggtttttc cagggattgg ttctgtttca ccgttcttcc
     4081 aatctttaat ttccccgtat ggttgagcga tttccccttg agtattatgt cctagtggtg
     4141 cgctcttaag atcatagaag gttcccggca tgtatttctt tgccatttca gaaacagtct
     4201 tagccaagag cttgaattgt tgccagtcag actttgattc ccacattgga ctaactgctg
     4261 cattaaatgg gtgaataaat ggatgcatat cagttgatga aaggtccttc ttttcatacc
     4321 aagtagcagc tggtaggaca acatcggagt acattggtgt tgaaaccatt cggaagtcca
     4381 tatcaacaac aagatctaac ttaccaattg ctcctttatc acgccaaatc atatcctggg
     4441 gcttaactcg atcattaggt ttagcaagca atccattttc agcgcctaat aaatgtttca
     4501 taaagtattc ggcacctttg ccagaagaag caaataagtt tgaacgccat aagaagaacg
     4561 ctttgggttg attttggtta gcatcaggat cttcagcagc aaaatgtaaa gagcccttct
     4621 tcaattcatc gacaactttc tttgaaattt cattaatatc agttgtattg taatcttttg
     4681 caaaagataa cggattacga tcaaattgtg ggtatgatgg taaccatcct aaacgaattg
     4741 ccatttgatt ataatcagca ttatgtaagt aggaatgttt actcttccaa acaggtgatt
     4801 tttgagcttg gttatcaatt tcttcataac gccattgatc agttgcaaag taataccaag
     4861 tagtaccttg catttgacgg gcaccacctt tttcccagtc attagcaaaa gtaatatttg
     4921 cccaaccctc ttgtggacgg agcttttctt gaccaacgta gtgagcccaa ccaccaccag
     4981 tcataccaac acaaccacac agcatcagca tattaataat gtttcgatag ttcatatcgg
     5041 cattgaacca gtggttgacc ccaccaccca tgattaccat actccgccct tcattttcgg
     5101 ccgcgttttg ggcaaattca cgagcaattt gaataacttg ctctgctttt actcccgaac
     5161 ggctttcttg ccaagcagga gtaaagtaac tctcagcatc cattgcatct ttagcagcaa
     5221 gttcatcatt accagtccga ttaattccca tttgagccat cattaagtcg taaacattag
     5281 taaccaagtg ttcttgacca tctgtgaatt tgagcttttt aactggtaaa tgccgttgaa
     5341 caacgctgtt tccgtcatta ctaaatgcag ggaaatcagc aataatttgt tcagtttctt
     5401 caccttgatc attaatagaa agtgccggat caatcttatt gccattttgg tctaataatt
     5461 caagattcca tttttcttta gcattatatt cctgacccat cgttccattt ggaacaacaa
     5521 ttttgtggtt attttggtca taaaccactg tcttccatgc tggattaaca atcgtatcat
     5581 catcaactaa gtcactaatc cgaacaaaac gacctggtgt atagtgatca tcatttgctg
     5641 tacttggttc caattcaacc atgaatggta aatcagtaaa tcgcttagaa taatcaatga
     5701 aacgtttgac tgggtgcttt tggtagaatt catctaaaat tacataagtc atcgcttgag
     5761 caacaccaga atcactacct ggttctggtg caagccagtc atcagcgaat tttacatttt
     5821 cagcataatc agggctaact actacaatct ttgttccctt gtacctaact tctgtcatga
     5881 agtgtgcatc tggtgtccga gttaatggaa cgtttgatcc ccacataata atataggaac
     5941 tgttatacca ttctgcagat tctggaacat cagtctgttc accccaaact tggggagacg
     6001 caggcggtag atcagcatac caatcgtaga aactcatttg ttccccaccc attaaggcga
     6061 tgaatcgggc tccggcactg aaactcatca ttgacattgc aggaattggg gtaaaaccac
     6121 caatacggtc gggcccatat ttcttaattg tgtataagca agcagctgaa atcatttcta
     6181 atgcttcata acgatgaaca cgaattaagc caccgtgtcc tcggaccttt ttatactttt
     6241 tagacttttc tggatcttcg acaatacttg cccacgcatc taagggattt tcatgttctt
     6301 tcttggcagc agtccaaagc tcccataatt taccacgaat atatgggtac ttaattcgaa
     6361 cgggactata ttcataccaa gagaaactag ctccccgtgg acatccccgt ggttcatatc
     6421 ctggaatatt aggtccgcat gatggataat ctgtagcttg atgttcccaa gtaataattc
     6481 cttgcttgac ataaacattc caagaacatg agcctgtaca gttgactcca tgagttgttc
     6541 ggacaacttt gtcatgcgcc catcgctgac gataaagctt ttcccaacga cgactatttt
     6601 cttcaagttg tgtaaaggtt ccattaaact tatcaacctt gttaaagaac cgtgacttca
     6661 tcgttgattg acctccttta ttggatggct taccaatatt aaaaataaag taagtctttt
     6721 ccctaatgta aagattagca ccataactgc tatactacga ctagggaaat acctatattt
     6781 tcgaactaaa tgaggtgtta atagccatga atcgttacga tcgtcaagaa agggtacatc
     6841 aaattggtgt cgttggtcag caaaaaatta gccatgcaac tattatgatt gtcggtgtag
     6901 gagcattggg aagttataca gctgagcaac ttgtccgtgc tggagttaaa agacttgtct
     6961 taattgatcc tgacactgtt gatgtaacta atcttcaacg tcaatcgctt ttcaccgaag
     7021 cagatgctaa ccaacaacgc cttaaggtcg aagcagctaa tgaacattta catgaaatta
     7081 attcagcatg tcaaattact gcgatcccag cgccgattac tgctgacctt attgacgaat
     7141 atcagtttac cctttgttta gactgtcttg ataattatca agcacgggac ctattaaaca
     7201 aattagcaat catcaaaaat tttgattatc tgtttgccag ttgtgcaggt acctatggga
     7261 atgtaatggc aatttcgccg caaaatcatc cttgcttgaa ctgtcttttt cctaatatca
     7321 atgaattaaa acaaaacgat tgtgatttaa ttggggttaa tactgcttta attcctattg
     7381 tagcgggact acaggtatct ttagcgcttc attatctagt tgataaaaca caggttaatt
     7441 ttaatgaatt gatcactgtt gacaattggt caatgcaatt tagtaagttt gctattaata
     7501 aaaattgcca ttgtcccgcc tgtgctaagc ctagcagtat ttctttagaa gaagaatcag
     7561 caccagaatt acatatgtta tgtggggaaa atgcatatta tacagtcaaa gagaaaccta
     7621 ttaattttgg cagacttaaa gaatttttgg ctaaaaaaga gctcttaatt aacgcaaatc
     7681 gattgtttct tcattttaaa tgggaaaatc gtccagtaag tatattcaag aatggtaaga
     7741 ttgttatgta tgacttacct acttcggcga ttgcccagaa acagtttgag tcattaaata
     7801 ctttaatgaa agaagaccta ttatgaaaaa aatcgcaatt ttaacggtta gcgatagtcg
     7861 aacattagat agcgatactt ctggaaaatt aattgctatg aagatggcta atgcgggcct
     7921 atcagtagtt gatcgggtaa tcgttaatga tgatattgtc aatattcaaa ctgcctacct
     7981 tcaactagaa caacaagcta ttgatatcat cattactaat ggtggaacag gagttgctca
     8041 gcgtgatgtt actattccgg ctatccgtcc actcctcaaa cgcctaattc ctggttttgg
     8101 ggaagcgttt cgccagatat catttgatga aatcggtact cgagctcttg catcacaagc
     8161 actagccgga tttaactacc gcaaccagct tacttattgt ttgccaggtt cccacaatgc
     8221 ttgtcaaaca gctctaagta aactaatttt gccagaatat gaacatttat tatttgaaag
     8281 cagttcccaa cgaaaggaag ttcaccacca tgctcactag aagaacacca atctctgttg
     8341 ccgaggcaca gaaaaagatt aacgaaatcc ccctgaaaac aactacagaa acaattcccc
     8401 tatcagaagc taaccatcgt attttagctg aggatgtcca tgctcattat gactatcctc
     8461 attttcgccg agcaggaatg gatgggtatg caattttagc cagcgatgat catgacttcc
     8521 cccgcgagtt taatgtccga ggagagattc aagctggagc aacttgggat caaccattac
     8581 agccagggga tgcagttcgg ataatgactg gtgcatatgt cccttctgat gcggggaaag
     8641 taattcgaat tgaaaaaact cgtcctgctg aagataaaaa taaggttcaa attattacaa
     8701 ctgagagtaa aactaacatt acagaaactg gtactgatgt aaaaagcggt gatatcgttt
     8761 tagcaaaaga tcaggaaata aatcccggtg gcctagcagt cttaacggct tttggtgttc
     8821 aagaagtaac agtttataaa aaaccacgga ttgcaattat cgccactgga actgaattat
     8881 taggccctaa tgagacaatt gaacagggaa agatctttaa tagtaatggc attatgttaa
     8941 aaaatctggt agaagaaact ggtgggattg ttgattttga aacccaatta ccagatgatg
     9001 ctaatcttat caagcagact cttgaagaac aaatagcaac tcatgaaatt gtaattactg
     9061 atggtggcgt ttctgtcggt gattttgatt tcattggaga tgaagcacgt aaagctgatg
     9121 aattgctgtt taataagatt aagcaacgac caggaagcgt tacgactgcc tttgttcaaa
     9181 ataatacgtt agtaatggct ctttctggaa atccaggcgc ttgttttact ggcttttatc
     9241 tctacatgga accgctgatt cgacgctatc aacaccaagc aagccgaatt aagcgagtac
     9301 gggcaatatt agcagcccca tataataaaa ctaacggctt tgatcgttac cttcgttgta
     9361 cttatgaatt caaagatgat caattttatg tttatccaaa tggaatcaac cgatctggct
     9421 cattagctaa cctccagacg acgacctgtt tggcattgat tccgcatagt acaactccaa
     9481 tgaaggtcgg aacggagact gatgcatggc tattaccctt caaataattg gtcataagaa
     9541 aagcgggaag actcttatca tgacggcttt aattgaaagg ctttcaaaag aaggatatcg
     9601 agtagctgct cttaaacatg atgcccataa tgctgcaatg gatgtgccaa ctactgacag
     9661 tgctagaatg agtaacgctg gagcaaacca agttatcttg caatctgcaa ctgaattttt
     9721 ctttcatcaa aaaagtaatg ttccaacttt aacggaaatg gttgagttgt taagtgacga
     9781 caatgatttt gtcttgattg aaggccataa ggaagccaat caatatccgc aaattttatt
     9841 attaaagcct ggcgaagatc ctactaatat tgctcctact acgccgctta aaaccggtag
     9901 tatttttagt gggacaaatg ctgacttact agggaaaaat acaattgtaa actggtgcta
     9961 taactactta aaacaaataa aggagaatac ttgatgattg gattagtata cgcgggcggc
    10021 aaatctattc gctttggtaa agacaaggct acttatcatg ttccaagatt accagctacc
    10081 aatgtacagc tagcagttga gaaactaatg cccctttgtc agcagatcat tgtttgtgct
    10141 aatgaaacaa atcgtgcaca tataatagaa ttagttggtc aggtaccggc tgtgcagatt
    10201 atctgtgata ttcctcctta tgatcatcat ggtccccttt cagcaattat tgcttgtact
    10261 agtcaatttt ccgttgttca agactattta actttggctg ttgattatcc atatatcaca
    10321 aaagatgtac ttgccattct tgctcgtaca tccaactctt atattgtaac aagtcagcat
    10381 agtcattatt cattagctca tttttcaatt agcaatgaac aagttactac atgggttgat
    10441 aataatagtg actggcgatt acgtagtttc atcactaata aatgcgggtg tcatcccctt
    10501 gcatatcgct caagtgccga attttcaaat ttaaactatc gtgaggtcga tttaaatgaa
    10561 aagtaaagat tcaatgacaa atcctgattt tcaaaaactc atttcccttg tcttaaatga
    10621 cttaacaatc agacgaacaa tgttagaaaa tcgggaacaa gaagtaaacc aacaaatgag
    10681 ttcactggaa aaagatgctg aattggagca attggatgac caaattcaac aaattcaagc
    10741 tgattttgat cattaccgcg aattccaaga tccggaattt gattttagtg caaccaagta
    10801 tttccaggga ccatcgatgg ggttaccacg acatccttaa aagctagatg gcagggctaa
    10861 agaagcagag cttttcttag ccctgccttt taagttgtct atcgttgctt ctaaccaaag
    10921 aaagcgttaa tatataaaat aggaatatta tgatagcgat tggggaattt tatttaggag
    10981 gaagcagatc gtgcttgaaa cagctaattg gatacaaaaa tattttaatc aatcaccaga
    11041 tgcaatcttc ttatttaaaa atgatgatct tttagttagt aatgagccgg cacaacggtt
    11101 agttactatg tttaatttag atgtcaatta cctattacaa attggaaaga acgcttggtc
    11161 acaactggaa aatgatgact gtgcgtcatg tctgattaaa aagcggttaa aaggagctgc
    11221 agttccgata acatttcatt ccaatgctac tcatcccttt cacttttcaa tggtttatcg
    11281 tcctcttgat gataaagaaa atgtctttgc cctaactctt gaaaatcgtg agcaacagca
    11341 gcgcctttct caagttgagg agcaacgaat tctcaatcaa tatgtcaatg aagcgcatga
    11401 aaaggaacgg caaaaaatct cacaagatct tcacgatagt gttgcgcagg gaatctacgc
    11461 ggcaataatg ggcattcaaa gattagcaac ggttcaaaat caaagaaaca ctgagcagtt
    11521 tcaatcaatg agtgctgcaa tcgaaaagca gttacaaacg acccttaaag agattaaaga
    11581 gctcgcactc gatattcgtc cctcggtgct cgataatttt ggcttaattc cagcaatcaa
    11641 agctttggca aaacggcttc aaaatagtac aggaatcacg attaatgtta tagcccttac
    11701 ctctgccgaa aacctgcaaa aaaatattca aaacgttctt taccgaatta cacaagaggc
    11761 aattaataac gcaattaagc atgctcattc aacagaaata actattattg ttaccaacca
    11821 taatagttac cttcagttag agatccttga taatggtatc ggctttgatc ttgaacagca
    11881 tagcagattt aatgggcatt cacttggatt aatgaatatg aatgaacgcg ttaaggcata
    11941 taatggggcc tttacaatta catcaaaaat taataaggga acgacagtca aggtgaagtt
    12001 tccctataat aatttaaata aggatacggt gagaacaaat gtataacgtt ttagttgcag
    12061 acgaccacgc aatcgttcgt tcaggaattt catatttagt cgatcttcaa ccgaatttta
    12121 cggtggttga tgggacagcg agtggaacag atacatatat tcgagttgaa caaggtggaa
    12181 ttgacatttt aattatggat ttaagtatgc cccctggcga aaatggtctg attacgactc
    12241 ggcgaatcca tgacaagttt ccaaaagtta aaattatcat tctctcgatg cacgaagaac
    12301 aggagtatat caataaggca atggcaaatg gcgcaatgtc ttatattttg aagagttcac
    12361 cggatagcga aattgttaac gcccttaaac atgttataaa tggtgaaaaa taccttgatg
    12421 caaacatcat tgttagtaag aaagacatta aggaaataaa tgcttctggt aataccttaa
    12481 aattaaaggg ctataatggt ctctctaaaa gagaaaaaga agtctttcca cttattgctt
    12541 tagggtattc aaataaagaa atctcccaaa agatgtttat ttcaacaaag acagtagaag
    12601 cacataaagc aaatatttca cgcaaacttc atttacatgg acgggttgaa ctagtacaat
    12661 atgctattca tcaccattta attgaccttt aactagcggg gattctgaat taagaagaat
    12721 ccccgatttt atttacttcg atattttttt acaataaaag aaatacgatt aaaggagtgg
    12781 atttataatg gcgacgaacc tcagtcgaga ggatgagttg cggggaatcc tcagtgatgt
    12841 tgctcgcaaa cactttacta atagtcgaca agttaatccc gtttccaacc tgtttttaac
    12901 aactaaatat gcagttgaaa accaatatat ttctggagca gttattgacg aatcatttag
    12961 ttcaacatta gcagagataa atttaaaaaa tgctgtttta actgatcgcg gtcgtaataa
    13021 gcttgcacaa cttctcaccc aatcagcaaa ggagaattaa ttaagatgga tattcaagat
    13081 aagctaaaac gagattacga aaataaatcg atctatactg caggctttta cgcagaccca
    13141 gataatgacc ttgcaaatcg taaaaaatta tttgatgtct taaaatcact agttgagaat
    13201 caagaagcca caacgccatt tgctttacaa atcatgctta caaatggcga aattaatgta
    13261 atgcccctcg gcctcgttga tcttgatgaa cttaaaaaat atgaaaatga acaacgatct
    13321 aagcatggtt tagatgaaca taacgatgat attcctcttc taatccaata tgcccctcat
    13381 gcagagaaaa aagaagtggt taaaaaaaga ataggtacag ttcaagatct ttttacaaac
    13441 tttaacgagc aaattgaaaa aatatggcaa actattaaga aatttatgca ggataatttt
    13501 gctttattaa cgactatcga aaaggatttg attgctgata gtcaaaatgt gatgcaagaa
    13561 tatcggatta ctttttccaa gatgactgag gctgaacgaa aagaaaagct ggggtttagt
    13621 gttccggaaa atgaaatcaa ccaattttgc cgttacatgg ctgatatgca tgaagtacaa
    13681 gcagtcgtat tatctgctgg tgctttcgtt aaccatgaac ttcttggtaa aaattccttt
    13741 actgagatga taagcgataa cattcgacgg agtaccctct tctgggttct tgataatacc
    13801 ttctacgaaa tttactacta cttctacatg agcaatgcca atgataagct tcataaacga
    13861 cttaaacatc aacgagaaac ctttatcgtt aatatgcgta atgatgcttt tcaccgtgca
    13921 caagaattta ctgaaaagca aacaaaaaag gttgatttta atgaatactt cagtgatatc
    13981 ttcatccccg ttgctgaaca aataattgct gaagtaaata aatttaagga ctgatactgt
    14041 gaatttaaca ccagatgaac ggctggcaga tgcattaaca accattattt atcaatatcc
    14101 tccaatggtt cgtgaaatga ttaatattaa tgccggtgaa aaagaacgtc tgctaagatt
    14161 atcgattttt gaagctttca gtcacctcag cgaaagagat cttacgattg atcaaatcac
    14221 agctgctcaa ttaccggaac tattggcatt agcaactcat ttgaatcctc cttcttttca
    14281 accaaataac ctaactcctg gggaattcgc tagtcaaaag gcatattcat atgttgcgag
    14341 ctatttgatg aatcgctttg tccattcgtt aagtactgta ggtaatcccc cacaggtact
    14401 tgaagagttg ataactgacg ctggggatgt gatgcttgca caggttcgac ggctgcagtt
    14461 taactataat cagcaattta aggtagctga ttatttagca gatgttaaag cacggtgggg
    14521 attacttgga gcaatgaccg caaaacaaag tgccgtcctt agtggagcag gaaatgaaat
    14581 tgtctcgctt gcaggacaga ttggtcaagc ctttggtact gctagttata ttacacatga
    14641 gtttcaacag cttagcaatg atcccaactt gtttataaag atgataacgg ctggacagta
    14701 tccactggca cttttattcg ctcgtcaaca agatccacaa tggtttaata attttttctc
    14761 ttcaaatcat cgtccttcac aagagatatt taaccaagct tataacttag tgcttagccg
    14821 cactgatgat gtcaaacaac tgatcaccga tatcttctcc cagttaatcc ttgatattga
    14881 agtattaccg actggtcaaa ctcaggatga attgcttaaa ctagttgaag aattaaaaaa
    14941 ataatttaaa actaaaaatg gagattaagg aagaaattat cctcatctcc attttttaat
    15001 gtgcttattt aacgatatga acgtcaccat gaatataatg tttccataga gcaaaccagc
    15061 aaattgcact ggttagcgct aaaagcgcaa ttccaagctc ataactacct gtccattggt
    15121 aaatataacc aataattagt ggtgggaaga atccccccag gccaccaaca gctccaacaa
    15181 aaccagtaac tgctcctgta ttaccttggg atacatacgg aaccatttta aagacaaccc
    15241 cgttacctat tccggcagaa agaccaacca aaacaattcc tgcgataaac atgaattgat
    15301 tgtggaaact aagcataatc caaatagcaa agataacgat tgctacaaag acccattgta
    15361 ataatgccat cggtcgtttc ctatcggcaa ggtaaccacc aaatggccga actaacgtac
    15421 atacaaaggc aaataaggcc gaataaagac ctgctgtaac aggagtataa tggaacatcc
    15481 cagttaagaa tgtcggcgtt aaatttgtaa aggcaacgaa taaaccgaat gtaaggaaat
    15541 agaacagtga taggtaccat gttccactgt ctgtggcaac agataatgct ccctttatcg
    15601 tcttgctttt atcaactggc atttccttac aaaaaactgc aaagagaaca ccaaagatca
    15661 ctgtaagaat aatcaagaag taataaacac tatcaaatcc cgccgcctta gaaatatacg
    15721 gtaaagtcat tgcagctaca gcattcccca tgtttcccat tgagacaatc ccaagagcta
    15781 gtccctgctg ttctggcggg aaccaaactg aagcataaga aactccaaca gcaaatgatg
    15841 ttcctgacat cccaacgagc aatgcagcaa agagcaacat cccgaatgaa tggacatgtg
    15901 gaatcataat tagtggaatc aaaataaaag ccatcaaaat caaatagacc tttttcccac
    15961 cataacgatc acttaagatc cccactggaa ttcgcataat tgaccccaaa aggacaggcg
    16021 ttgctaataa taacgttcgc tgcgatacat cc
//
