LOCUS       c00137_gnlPro..        16142 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ENPFEMDD_181.
ACCESSION   c00137_gnlPro..
VERSION     c00137_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 05:16:59
            Original ID  :: gnl|Prokka|ENPFEMDD_181
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 6005
            Orig. end    :: 22147
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16142
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[16005:21909]"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15904
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
     cand_cluster    1..16142
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /kind="single"
                     /product="Nitrate_reductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16142
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Nitrate_reductase"
                     /region_number="1"
                     /rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /tool="gutsmash"
     CDS             complement(1155..2060)
                     /locus_tag="ctg137_11"
                     /transl_table=11
                     /translation="VNLTPDERLADALTTIIYQYPPMVREMININAGEKERLLRLSIFE
                     AFSHLSERDLTIDQITAAQLPELLALATHLNPPSFQPNNLTPGEFASQKAYSYVASYLM
                     NRFVHSLSTVGNPPQVLEELITDAGDVMLAQVRRLQFNYNQQFKVADYLADVKARWGLL
                     GAMTAKQSAVLSGAGNEIVSLAGQIGQAFGTASYITHEFQQLSNDPNLFIKMITAGQYP
                     LALLFARQQDPQWFNNFFSSNHRPSQEIFNQAYNLVLSRTDDVKQLITDIFSQLILDIE
                     VLPTGQTQDELLKLVEELKK"
     CDS             complement(2065..3033)
                     /locus_tag="ctg137_12"
                     /transl_table=11
                     /translation="MDIQDKLKRDYENKSIYTAGFYADPDNDLANRKKLFDVLKSLVEN
                     QEATTPFALQIMLTNGEINVMPLGLVDLDELKKYENEQRSKHGLDEHNDDIPLLIQYAP
                     HAEKKEVVKKRIGTVQDLFTNFNEQIEKIWQTIKKFMQDNFALLTTIEKDLIADSQNVM
                     QEYRITFSKMTEAERKEKLGFSVPENEINQFCRYMADMHEVQAVVLSAGAFVNHELLGK
                     NSFTEMISDNIRRSTLFWVLDNTFYEIYYYFYMSNANDKLHKRLKHQRETFIVNMRNDA
                     FHRAQEFTEKQTKKVDFNEYFSDIFIPVAEQIIAEVNKFKD"
     CDS             complement(3039..3311)
                     /locus_tag="ctg137_13"
                     /transl_table=11
                     /translation="MATNLSREDELRGILSDVARKRFTNSRQVNPVSNLFLTTKYAVEN
                     QYISGAVIDESFSSTLAEINLKNAVLTDRGRNKLAQLLTQSAKEN"
     CDS             complement(3407..4060)
                     /locus_tag="ctg137_14"
                     /transl_table=11
                     /translation="MYNVLVADDHAIVRSGISYLVDLQPNFTVVDGTASGTDTYIRVEQ
                     GGIDILIMDLSMPPGENGLITTRRIHDKFPKVKIIILSMHEEQEYINKAMANGAMSYIL
                     KSSSDSEIVNALKHVINGEKYLDANIIVSKKDIKEINASGNTLKLKGYNGLSKREKEVF
                     PLIALGYSNKEISQKMFISTKTVEAHKANISRKLHLHGRVELVQYAIHHHLIDL"
     CDS             complement(4053..5126)
                     /locus_tag="ctg137_15"
                     /transl_table=11
                     /translation="LGRKQIVLETANWIQKYFNQSPDAIFLFKNDDLLVSNEPAQRLVT
                     MLNLDVNYLLQIGKNAWSQLENDDCASCLIKKRLKGAAVPITFHSNATHPFHFSMVYRP
                     LDDKENVFALTLENREQQQRLSQVEEQRILNQYVNEAHEKERQKISQDLHDSVAQGIYA
                     AIMGIQRLATVQNQRNTEQFQSMSAAIEKQLQTTLKEIKELALDIRPSVLDNFGLIPAI
                     KALAKRLQNSTGITINVIALTSAENLQKNIQNVLYRITQEAINNAIKHAHSTEITIIVT
                     NHNSYLQLEILDNGIGFDLEQHSRFNGHSLGLMNMNERVKAYNGAFTITSKINKGTTVK
                     VKFPYNNLNKDTVRTNV"
     CDS             complement(5259..5543)
                     /locus_tag="ctg137_16"
                     /transl_table=11
                     /translation="MKSKDSMTNPDFQKLISLVLNDLTIRRTMLENREQEVSQQMSSLE
                     KDAELEQLDDQIQQIQADFDHYREFQDPKFDFSATKYFQGPSMGLPRHP"
     CDS             complement(5533..6105)
                     /locus_tag="ctg137_17"
                     /transl_table=11
                     /translation="MIGLVYAGGKSTRFGKDKATYHVPGLPATNIELAVEKLTPFCQQI
                     VVCANEINRAHILELVGQEPAVQIICDIPPYDHHGPLSAIIACTGHFSTLQDYLTLAVD
                     YPYLTKDSLAVLARTSNSYIATSQHNHYSLAHFSVSNEQVTTWVDNNDDWRLRSFITNK
                     CVCHPLKYRSSNEFSNLNYREVDLNEK"
     CDS             complement(6102..6593)
                     /locus_tag="ctg137_18"
                     /transl_table=11
                     /translation="MAITLQIIGHKKSGKTLITTTLIERLSKEGYRVAALKHDAHNAAM
                     DVPTTDSARMSSAGAKQVILQSATEFFFHQKSNVPSLTEMVELLSTDNDFVLIEGHKEA
                     TQYPQILLLKPGEDPTNVAHTPPLKIGSIFNGTTADLLGKDAIVNWCYDYLKQVKGDAG
                     "
     CDS             complement(6572..7840)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg137_19"
                     /sec_met_domain="MoCF_biosynth (E-value: 3.3e-23, bitscore:
                     72.7, seeds: 114, tool: rule-based-clusters)"
                     /sec_met_domain="MoeA_C (E-value: 1.7e-13, bitscore: 41.5,
                     seeds: 41, tool: rule-based-clusters)"
                     /sec_met_domain="MoeA_N (E-value: 4.1e-38, bitscore: 121.4,
                     seeds: 1302, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIYYLKAVLNERKFITMLTRRIPISVAEAQKKINEIPLKTATET
                     IPLSEANHCVLAKDVHANYDYPHFRRAGMDGYAILASDDHDFPREFNIRGEIQAGATWD
                     QPLQSGDAVRIMTGAYVPSDVGKVIRIEKTRPAKDENKVQIITTESKTNITEAGTDVKS
                     GDIVLAKDQEINPGGLAVLTAFGVQEVTVYKKPRIAIIATGTELLGPNATIEPGKIFNS
                     NGIMLKNLVEETGGIVDFETQLPDDADLIKQTLEEQIATHEIVITDGGVSVGDFDFIGD
                     EARKADELLFNKIKQRPGSVTTAFVQNNTLIMALSGNPGACFTGFYLYMEPLIRRYQHQ
                     ASRIKQVRAILAAPYNKTNGFDRYLRCTYEFKDNQFYVYPNGINRSGSLANLQTTTCLA
                     LIPHSTTPMKVGTETDAWLLPFK"
     CDS             complement(7779..8276)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg137_20"
                     /sec_met_domain="MoCF_biosynth (E-value: 1.2e-33, bitscore:
                     106.6, seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIAILTVSDSRTLDSDTSGKLIAMKMANAGLSVVDRVIVNDDI
                     VNIQTAYLQLEQQALDIIITNGGTGIAQRDVTIPAIRPLLKRLIPGFGEAFRQISFDEI
                     GTRALASQALAGFNFRNQLTYCLPGSQNACQTALNKLIFPEYEHLLFESSSQRKEVHHH
                     AH"
     CDS             complement(8273..9430)
                     /locus_tag="ctg137_21"
                     /transl_table=11
                     /translation="LTSFIEWLTNIKNKVSLFPNVKISTITAILRLGKYLYFELNEVLI
                     SMNRYDRQERVHQIGSIGQQKISHATIMIVGVGALGSYTAEQLVRAGVKRLVLIDPDTV
                     DVTNLQRQSLFTEADASQQRLKVEAAKEHLHKINSVCQITAIPAPITADLIDEYQFTLC
                     LDCLDNYQARDLLNKLAIIKNFDYLFASCAGTYGNVMAISPQNHPCLNCLFPNINELKQ
                     NDCDLIGVNTALIPIVAGLQVSLALHYLVDKTQVNFNELIAVDNWSMQFSKFAINKNYH
                     CPTCAKPSSISLEEESAPELHMLCGENAYYTIKEKPINFGRLKEFLAKKELLINANRLF
                     LHFKWENRPVSIFKNGKIVMYDLPTSAIAQKQFKSLNILMKEDLL"
     CDS             9543..9818
                     /locus_tag="ctg137_22"
                     /transl_table=11
                     /translation="MTKLFEQLMELTVQARVLGMFMSSKELLLGNTKPQIIHHADLIFQ
                     DMNHGDVLGELVSLGMNTVPFELSIHIFVASYGSFGLLPRKNMKIP"
     CDS             10001..13102
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molybdopterin"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molydop_binding"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_23"
                     /sec_met_domain="Molybdopterin (E-value: 9e-124, bitscore:
                     404.4, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 1.3e-22,
                     bitscore: 70.8, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMMSFSAGARFIALMGGEQMSFYDWYADLPPASPQVWGEQTDVP
                     ESAEWYNSSYIIMWGSNVPLTRTPDAHFMTEVRYKGTKIVAVSPDYAENVKFADDWLAP
                     EPGSDSAVAQAMTYVILDEFYQKHPVKRFIDYSKRFTDLPFMVELEPSTANGDHYTPGR
                     FVRISDLVADDTIVNPAWKTVVYDQNNHKIVVPNGTMGQEYNAKEKWNLELLDQNGNKI
                     DPALSINDQDGETEQIIADFPAFSNDGNSVVQRHLPVKKLKFTDGKEHLVTNVYDLMMA
                     QMGINRTGNDELAAKDAMDAESYFTPAWQESRSGVKAEQVIQIAREFAQNAAENEGRSM
                     VIMGGGVNHWFNADMNYRNIINMLMLCGCVGMTGGGWAHYVGQEKLRPQEGWANITFAN
                     DWEKGGARQMQGTTWYYFATDQWRYEEIDNQAQKSPVWKSKHSYLHNADYNQMAIRLGW
                     LPSYPQFDRNPLSFAKDYNTTDINEISKKVVDELKKGSLHFAAEDPDANQNQPKAFFLW
                     RSNLFASSGKGAEYFMKHLLGAENGLLAKPNDRVKPQDMIWRDKGAIGKLDLVVDMDFR
                     MVSTPMYSDVVLPAATWYEKKDLSSTDMHPFIHPFNAAVSPMWESKSDWQQFKLLAKTV
                     SEMAKKYMPGTFYDLKSAPLGHNTQGEIAQPYGEIKDWKNGETEPIPGKTMPSLKLVTR
                     DYTKIYDKYITLGPNIVNNYNYKVDDQYDYLKDMNGIASEGIGAGCPLLDEDEKVCDAI
                     LRMSTASNGKLADRAWEKKQERTGEHLTDIGRGHADDSMSFKQITAQPQEAYPTPIGTS
                     AKHGGARYTPFSLMTERNIPTFTLTGRQHFYIDHEIFREFGENMATYKPSLPPVVMAPG
                     DVDVPPVKDEVTLKYMTPHGKWNIHTMYYDNLEMLTLFRGGPTTWISPQDADKIKVKDN
                     DWIEVYNRNGVVTARAVVSVRMPEGSMYMYHAQDNEIYEPLSTITGNRGGSHNAPTQIH
                     IKPTHMVGGYSQLSYGWNYYGPTGNQRDLYANVRKLKKVNWSED"
     CDS             13092..14651
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Fer4_11"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitr_red_bet_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_24"
                     /sec_met_domain="Fer4_11 (E-value: 5.3e-39, bitscore:
                     123.3, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00084, bitscore: 10.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Nitr_red_bet_C (E-value: 2.6e-28,
                     bitscore: 88.4, seeds: 110, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIKAQISMVLNLDKCIGCHTCSVTCKNTWTNRPGAEYMWFNNVE
                     TKPGVGYPKRWEDEDQYHGGWTLNSKGKLKLRAGSKLNKIALGKIFYNNDMPELDNYYE
                     PWTYDYKTLFGPEQKHQPVARPKSQITGEGMELITGPNWDDDLAGSTEYVQQDPNMQKI
                     EGDIKNNFEQAFMMYLPRLCEHCLNAPCVASCPSGAMYKRDEDGIVLVDQERCRGWRFC
                     MTGCPYKKVYFNWKTHKAEKCTFCYPRIEEGQPTVCAETCVGRIRYIGAILYDADRVEE
                     AASTPDESKLYEAQLGLFLDPNDPEVVKQALKDGISEEMIEAAQKSPIYKMAVKEKIAF
                     PLHPEYRTMPMVWYIPPLSPVMSYFEGRDSIKNPEMIFPGIDQMRVPVQYLASLLTAGN
                     VPVIKKALYKLAMMRLYMRAKTSGRDFDSSKLERVDLTEERATSLYRLLAIAKYEDRFV
                     IPSSQKAEMEDAQTEQGSLGYDECEGCALAPQHKSMFKKAEAGKSTNQIYADSFYGGIW
                     RD"
     CDS             14644..15222
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_del"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_25"
                     /sec_met_domain="Nitrate_red_del (E-value: 6e-10, bitscore:
                     30.1, seeds: 108, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIDFRRLIDLKDTFAILSRLIDYPETETFSPEIRQLLLTDNALST
                     ATRGELLSLFDELAALSPIEVQEMYARLFEMNRRYTLYMSYYKMTDSRERGTILARLKM
                     LYEMFGISEATSELSDYLPLLLEFLAYGDYTNDPRRQDIQLALSVIEDGTYTLLKNAVI
                     DSDSPYIQLIRLTRSLIGSCIKMEVQEDA"
     CDS             15425..15904
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_gam"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_26"
                     /sec_met_domain="Nitrate_red_gam (E-value: 3.4e-51,
                     bitscore: 164.6, seeds: 140, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIPASWTAYFGITEHMYHIFGSLMMGIPAGILAFVGIAILTYRR
                     MTCSRVYKTSDINDIIVDWALLITIALGLASTITGAFIDYNYRTTISPWARSLFVLNPQ
                     WQLMRSVPLIYKIHVLCGLAIFGYFPYTRLVHALTLPWQYIFRRFIVYRRRARVY"
ORIGIN
        1 ctaactttgc tccacttgca tcccaggtcg ctgagatgtt caatttggat gtatcgcagc
       61 gaacgttatt attagcaacg cctgtccttt tggggtcaat tatgcgaatt ccagtgggga
      121 tcttaagtga tcgttatggt gggaaaaagg tctatttgat tttgatggct tttattttga
      181 ttccactaat tatgattcca catgtccatt cattcgggat gttgctcttt gctgcattgc
      241 tcgttgggat gtcaggaaca tcatttgctg ttggagtttc ttatgcttca gtttggttcc
      301 cgccagaaca gcagggacta gctcttggga ttgtctcaat gggaaacatg gggaatgctg
      361 tagctgcaat gactttaccg tatatttcta aggcggcggg atttgatagt gtttattact
      421 tcttgattat tcttacagtg atctttggtg ttctctttgc agttttttgt aaggaaatgc
      481 cagttgataa aagcaagacg ataaagggag cattatctgt tgccacagac agtggaacat
      541 ggtacctatc actgttctat ttccttacat tcggtttatt cgttgccttt acaaatttaa
      601 cgccgacatt cttaactggg atgttccatt atactcctgt tacagcaggt ctttattcgg
      661 ccttatttgc ctttgtatgt acgttagttc ggccatttgg tggttacctt gccgatagga
      721 aacgaccgat ggcattatta caatgggtct ttgtagcaat cgttatcttt gctatttgga
      781 ttatgcttag tttccacaat caattcatgt ttatcgcagg aattgttttg gttggtcttt
      841 ctgccggaat aggtaacggg gttgtcttta aaatggttcc gtatgtatcc caaggtaata
      901 caggagcagt tactggtttt gttggagctg ttggtggcct ggggggattc ttcccaccac
      961 taattattgg ttatatttac caatggacag gtagttatga gcttggaatt gcgcttttag
     1021 cgctaaccag tgcaatttgc tggtttgctc tatggaaaca ttatattcat ggtgacgttc
     1081 atatcgttaa ataagcacat taaaaaatgg agatgaggat aatttcttcc ttaatctcca
     1141 tttttagttt taaattattt ttttaattct tcaactagtt taagcaattc atcctgagtt
     1201 tgaccagtcg gtaatacttc aatatcaagg attaactggg agaagatatc ggtgatcagt
     1261 tgtttgacat catcagtgcg gctaagcact aagttataag cttggttaaa tatctcttgt
     1321 gaaggacgat gatttgaaga gaaaaaatta ttaaaccatt gtggatcttg ttgacgagcg
     1381 aataaaagtg ccagtggata ctgcccagcc gttatcatct ttataaacaa gttgggatca
     1441 ttgctaagct gttgaaactc atgtgtaata taactagcag taccaaaggc ttgaccaatc
     1501 tgtcctgcaa gcgagacaat ttcatttcct gctccactaa ggacggcact ttgttttgcg
     1561 gtcattgctc caagtaatcc ccaccgtgct ttaacatctg ctaaataatc agctacctta
     1621 aattgctgat tatagttaaa ctgcagtcgt cgaacctgtg caagcatcac atccccagcg
     1681 tcagttatca actcttcaag tacctgtggg ggattaccta cagtacttaa cgaatggaca
     1741 aagcgattca tcaaatagct cgcaacatat gaatatgcct tttgactagc gaattcccca
     1801 ggagttaggt tatttggttg aaaagaagga ggattcaaat gagttgctaa tgccaatagt
     1861 tccggtaatt gagcagctgt gatttgatca atcgtaagat ctctttcgct gaggtgactg
     1921 aaagcttcaa aaatcgataa tcttagcaga cgttcttttt caccggcatt aatattaatc
     1981 atttcacgaa ccattggagg atattgataa ataatggttg ttaatgcatc tgccagccgt
     2041 tcatctggtg ttaaattcac agtatcagtc cttaaattta tttacttcag caattatttg
     2101 ttcagcaacg gggatgaaga tatcactgaa gtattcatta aaatcaacct tttttgtttg
     2161 cttttcagta aattcttgtg cacggtgaaa agcatcatta cgcatattaa cgataaaggt
     2221 ttctcgttga tgtttaagtc gtttatgaag cttatcattg gcattgctca tgtagaagta
     2281 gtagtaaatt tcgtagaagg tattatcaag aacccagaag agggtactcc gtcgaatgtt
     2341 atcgcttatc atctcagtaa aggaattttt accaagaagt tcatggttaa cgaaagcacc
     2401 agcagataat acgactgctt gtacttcatg catatcagcc atgtaacggc aaaattggtt
     2461 gatttcattt tccggaacac taaaccccag cttttctttt cgttcagcct cagtcatctt
     2521 ggaaaaagta atccgatatt cttgcatcac attttgacta tcagcaatca aatccttttc
     2581 gatagtcgtt aataaagcaa aattatcctg cataaatttc ttaatagttt gccatatttt
     2641 ttcaatttgc tcgttaaagt ttgtaaaaag atcttgaact gtacctattc tttttttaac
     2701 cacttctttt ttctctgcat gaggggcata ttggattaga agaggaatat catcgttatg
     2761 ttcatctaaa ccatgcttag atcgttgttc attttcatat tttttaagtt catcaagatc
     2821 aacgaggccg aggggcatta cattaatttc gccatttgta agcatgattt gtaaagcaaa
     2881 tggcgttgtg gcttcttgat tctcaactag tgattttaag acatcaaata attttttacg
     2941 atttgcaagg tcattatctg ggtctgcgta aaagcctgca gtatagatcg atttattttc
     3001 gtaatctcgt tttagcttat cttgaatatc catcttaatt aattctcctt tgctgattgg
     3061 gtgagaagtt gtgcaagctt attacgaccg cgatcagtta aaacagcatt ttttaaattt
     3121 atctctgcta atgttgaact aaatgattcg tcaataactg ctccagaaat atattggttt
     3181 tcaactgcat atttagttgt taaaaacagg ttggaaacgg gattaacttg tcgactatta
     3241 gtaaagcgtt tgcgagcaac atcactgagg attccccgta actcatcctc tcgactgagg
     3301 ttcgtcgcca ttataaatcc actcctttaa tcgtatttct tttattgtaa aaaaatatcg
     3361 aagtaaataa aatcggggat tcttcttaat tcagaatccc cgctagttaa aggtcaatta
     3421 aatggtgatg aatagcatat tgtactagtt caacccgtcc atgtaaatga agtttgcgtg
     3481 aaatatttgc tttatgtgct tctactgtct ttgttgaaat aaacatcttt tgggagattt
     3541 ctttatttga ataccctaaa gcaataagtg gaaagacttc tttttctctt ttagagagac
     3601 cattatagcc ctttaatttt aaggtattac cagaagcatt tatttcctta atgtctttct
     3661 tactaacaat gatgtttgca tcaaggtatt tttcaccatt tataacatgt ttaagggcgt
     3721 taacaatttc gctatccgat gaactcttca aaatataaga cattgcgcca tttgccattg
     3781 ccttattgat atactcctgt tcttcgtgca tcgagagaat gataatttta acttttggaa
     3841 acttgtcatg gattcgccga gtcgtaatca gaccattttc gccagggggc atacttaaat
     3901 ccataattaa aatgtcaatt ccaccttgtt caactcgaat atatgtatct gttccactcg
     3961 ctgtcccatc aaccaccgta aaattcggtt gaagatcgac taaatatgaa attcctgaac
     4021 gaacgattgc gtggtcgtct gcaactaaaa cgttatacat ttgttctcac cgtatcctta
     4081 tttaaattat tatagggaaa cttcaccttg actgtcgttc ccttattaat ttttgatgta
     4141 attgtaaagg ccccattata tgccttaacg cgttcattca tattcattaa tccgagtgaa
     4201 tgcccattaa atctgctatg ctgttcaaga tcaaagccga taccattatc aaggatctct
     4261 aactgaaggt aactattatg gttggtaaca ataatagtta tttctgttga atgagcatgc
     4321 ttaattgcgt tattaattgc ctcttgtgta attcggtaaa gaacgttttg aatatttttt
     4381 tgcaggtttt cggcagaggt aagggctata acattaatcg tgattcctgt actattttga
     4441 agccgttttg ccaaagcttt gattgctgga attaagccaa aattatcgag caccgaggga
     4501 cgaatatcga gtgcgagctc tttaatctct ttaagggtcg tttgtaactg cttttcgatt
     4561 gcagcactca ttgattgaaa ctgctcagtg tttctttgat tttgaaccgt tgctaatctt
     4621 tgaatgccca ttattgccgc gtagattccc tgcgcaacac tatcgtgaag atcttgtgag
     4681 attttttgcc gttccttttc atgcgcttca ttgacatatt gattgagaat tcgttgctcc
     4741 tcaacttgag aaaggcgctg ctgttgctca cgattttcaa gagttagggc aaagacattt
     4801 tctttatcat caagaggacg ataaaccatt gaaaagtgaa agggatgagt agcattggaa
     4861 tgaaatgtta tcggaactgc agctcctttt aaccgctttt taatcagaca tgacgcacag
     4921 tcatcatttt ccagttgtga ccaagcgttc tttccaattt gtaataggta attgacatct
     4981 aaattaagca tagtaactaa ccgttgtgcc ggctcattac taactaaaag atcatcattt
     5041 ttaaataaga agattgcatc tggtgattga ttaaaatatt tttgtatcca attagcagtt
     5101 tcaagcacga tctgcttcct ccccaataaa attctctaat tgtctttata atattcctat
     5161 tttatataat aacgctttct cgagttagaa gcaacgctgg cccacttaaa aggcagggct
     5221 aagaaaagct ctgcttcttt agccctgccg tctgagtttt aaggatgtcg tggtaatccc
     5281 atcgatggtc cctggaaata cttagttgca ctaaaatcaa atttcggatc ctgaaattcg
     5341 cggtaatgat caaaatcagc ttgaatctgt tgaatttggt cgtccagttg ttctaactcc
     5401 gcatcttttt ccagcgaact catttgttgg cttacttctt gttcccgatt ttctagcatt
     5461 gttcgtctaa ttgttaagtc atttaaaaca agggaaatga gcttttgaaa atcaggattt
     5521 gtcattgaat ctttactttt catttaaatc gacctcacga tagtttaaat ttgaaaattc
     5581 gttacttgag cgatacttaa gggggtggca gacgcactta ttagtgatga aactacgtaa
     5641 tcgccagtca tcattattat caacccaagt agtaacttgt tcattgctaa ctgaaaaatg
     5701 agctaatgaa tagtgattgt gctgacttgt tgcaatataa gagttggacg tacgagcaag
     5761 aacagcaagt gaatcttttg tgagataagg ataatcaaca gccagagtta aatagtcctg
     5821 aagagttgaa aaatgaccag tacaagcaat aattgctgag aggggaccat gatgatcata
     5881 agggggaata tcacagataa tctgcacagc cggttcttga ccaaccaact ctaatatatg
     5941 agctcgattt atttcattag cacaaacaac gatctgctga caaaagggtg ttaatttctc
     6001 gactgctagc tctatattgg tagctggtaa tcctggaaca tgataagtag ctttatcttt
     6061 cccaaaacgg gtagatttac caccagcata tactaatcca atcatcctgc atcccccttt
     6121 acttgtttta agtagtcata gcaccaattt acaattgcat cttttcctaa taagtcagcg
     6181 gttgttccat taaagatact acctatttta agagggggag tatgagcaac attggtagga
     6241 tcttcgccag gctttaataa taaaatttgc ggatattgag tggcttcctt atgaccttca
     6301 atcaagacaa aatcattgtc ggtacttaat aattcaacca tttccgttaa agacggaaca
     6361 ttactttttt gatgaaagaa aaattcagtc gcagattgta aaataacctg tttagctcca
     6421 gcactactca ttctagcact gtcagtagtt ggcacatcca ttgcggcatt atgggcatca
     6481 tgtttaagag cagctactcg atacccttct tttgagagcc tttcgattaa agtcgtagtg
     6541 ataagagtct tgccgctttt tttatgaccg attatttgaa gggtaatagc catgcgtctg
     6601 tctccgttcc gaccttcatt ggagtagtac tatgcggaat cagtgctaaa caggttgtcg
     6661 tctggaggtt agctaatgag ccagatctgt tgattccatt tggataaaca taaaactgat
     6721 tatctttgaa ttcataagta caacgaagat accgatcgaa cccgtttgtt ttattatatg
     6781 gggccgctaa tattgcccgt acttgcttaa ttcggctggc ttggtgttga taacggcgaa
     6841 tcagcggttc catataaagg taaaaaccag taaaacaagc tcctggattc ccagaaaggg
     6901 ccattattaa cgtattattt tgaacaaagg cagtcgtaac gcttcctggt cgttgtttaa
     6961 tcttattaaa aagcaattca tcagctttac gtgcttcatc tccaataaaa tcaaaatcac
     7021 caactgaaac accaccatca gtaattacaa tttcatgagt tgctatttgt tcttcaagag
     7081 tctgcttgat aagatcagca tcatctggta attgggtttc aaaatcaaca atcccaccag
     7141 tttcctctac aagatttttt aacataatac cattactatt aaagatcttt cccggttcaa
     7201 tcgtggcatt aggtcctaat aattcagttc cagtggcgat aattgcaatc cgtggttttt
     7261 tataaactgt tacttcttga acaccaaaag ccgttaaaac tgctagacca ccgggattta
     7321 tttcctggtc ttttgctaaa acgatatcac cgctttttac atcagtacca gcttccgtaa
     7381 tgttagtctt gctttcagtc gtaataattt gaaccttatt ttcatcttta gcgggccgcg
     7441 ttttttcaat tcgaattact tttcctacat cagaagggac atatgcacca gtcataattc
     7501 ggaccgcatc ccctgattgt aatggttgat cccaagttgc tccagcttga atctctcctc
     7561 ggatgttaaa ttcgcgaggg aagtcatgat catcgctggc taaaatggca taaccatcca
     7621 ttccagcccg tcgaaaatga ggataatcat aattggcatg aacatcttta gctaaaacac
     7681 agtggttagc ttctgataac gggattgtct ctgtagctgt tttaagggga atttcgttaa
     7741 tctttttctg tgcctcggca acagagattg gaattcttct agtgagcatg gtgatgaact
     7801 tcctttcgtt gagaactgct ttcaaataat aaatgttcat attctggaaa aattagtttg
     7861 tttagagccg tttgacaggc attctgggaa ccaggtaaac aataggtaag ctgattgcgg
     7921 aaattaaatc cggctagggc ttgtgatgca agcgcacgag taccaatttc atcaaaagat
     7981 atctggcgaa acgcttcccc aaaacccgga attagacgtt tgaggagtgg acggatagcc
     8041 ggaatagtaa catcacgctg agcaattcct gttccaccat tagtaatgat gatatcaaga
     8101 gcttgttgtt ctagttgaag gtaggcagtt tgaatattga caatatcatc attaacgatt
     8161 acccgatcaa ctactgataa gcccgcgtta gccatcttca tagcaattaa ttttccagaa
     8221 gtatcgctat ctaatgttcg gctatcgcta accgttaaaa ttgcgatttt tttcataata
     8281 ggtcttcttt catcaaaata tttaacgact taaactgttt ctgggcaatc gccgaagtag
     8341 gtaagtcata cataacaatc ttaccattct tgaatatact tactggacga ttttcccatt
     8401 taaaatgaag aaacaatcga tttgcgttaa ttaagagctc ttttttagcc aaaaattctt
     8461 taagtctgcc aaaattaata ggtttctctt tgatcgtata atatgcattt tccccacata
     8521 acatatgtaa ttctggtgct gattcttctt ctaaagaaat actgcttggc ttagcacagg
     8581 tgggacaatg gtaattttta ttaatagcaa acttactaaa ttgcattgac caattgtcaa
     8641 ccgcgatcaa ttcattaaaa ttaacctgtg ttttgtcaac cagataatga agcgctaaag
     8701 atacctgtag tcccgccaca atcgggatta aagcagtatt aaccccaatt aaatcacaat
     8761 cgttttgttt taattcatta atattaggaa aaagacagtt caagcaggga tgattttgtg
     8821 gcgaaatcgc cattacgttc ccataggttc ctgcacagct ggcaaacaga taatcaaagt
     8881 ttttgatgat tgctaatttg tttaatagat cccgtgcttg ataattatca agacagtcta
     8941 aacaaagggt aaactgatat tcgtcaataa ggtcagcagt aatcggcgct gggatcgcag
     9001 taatttgaca tactgaatta attttatgta aatgttcttt agctgcttct accttaagcc
     9061 gttgttggct agcatctgct tcggtgaaaa gcgattgacg ttgaagatta gttacgtcaa
     9121 cagtgtcagg atcaatcaag acaagtcttt taactccagc acggacaagt tgctcggctg
     9181 tataacttcc caatgcacct acaccgacaa tcataatagt tgcatggcta attttttgct
     9241 gaccaatact accaatttga tgtacccttt cttgacgatc ataacgattc atggatatta
     9301 gcacctcatt tagttcaaaa tataggtatt tccctagtcg tagtatagca gttatggtgc
     9361 taatctttac attagggaaa agacttactt tatttttaat attggtaagc cattcaataa
     9421 aggaggtcaa tcaacgatga agtcacggtt ctttaacaag gttgataagt ttaatggaac
     9481 ctttacacaa cttgaagaaa atagtcgtcg ttgggaaaag ctttatcgcc agcgatgggc
     9541 gcatgacaaa gttgttcgaa caactcatgg agttaactgt acaggctcgt gttcttggaa
     9601 tgtttatgtc aagcaaggaa ttattacttg ggaacaccaa gccacagatt atccatcatg
     9661 cggacctaat attccaggat atgaaccacg gggatgtcct cggggagcta gtttctcttg
     9721 gtatgaatac agtcccgttc gaattaagta tccatatatt cgtggcaagt tatgggagct
     9781 ttggactgct gccaagaaag aacatgaaaa tcccttagat gcgtgggcaa gtattgtcga
     9841 agatccagaa aagtctaaaa aatataagaa ggtccgagga cacggtggct taattcgtgt
     9901 tcatcgttat gaagcattag aaatgatttc agctgcttgc ttatacacaa ttaagaagta
     9961 tgggcctgac cgcattggtg gttttacccc aattcctgca atgtcaatga tgagttttag
    10021 tgccggagca cggttcattg ccttaatggg tggggaacaa atgagtttct acgattggta
    10081 tgctgatcta ccgcctgcat ctccccaagt ttggggtgaa cagactgatg ttccagaatc
    10141 tgcagaatgg tataacagtt cctatattat tatgtgggga tcaaacgttc cattaactcg
    10201 gacaccagat gcacacttca tgacagaagt taggtacaaa ggaacaaaga ttgtagcagt
    10261 tagccctgat tatgctgaaa atgtgaaatt tgctgatgat tggcttgcac cagaaccagg
    10321 tagtgattct gctgttgctc aagcgatgac ctatgtaatt ttagatgaat tctaccaaaa
    10381 gcacccagtt aaacgtttca ttgattactc caagcgattt actgatttac catttatggt
    10441 tgaattggaa ccaagtacag caaatggtga tcactataca ccaggtcgct tcgtccggat
    10501 tagtgactta gttgctgatg atacgattgt caatccagca tggaagacag tggtttatga
    10561 ccaaaataac cacaagattg ttgttccaaa tggaacgatg ggacaagaat ataatgctaa
    10621 ggaaaaatgg aatcttgaat tattagacca aaatggtaat aagattgatc cggcactttc
    10681 tattaatgat caagatggcg aaactgaaca aattattgct gattttccag cgtttagtaa
    10741 tgacggaaac agcgttgtgc aacgtcattt accagttaaa aagctcaagt tcacagatgg
    10801 caaagaacac ttggtaacta atgtttatga tctgatgatg gctcaaatgg gaattaatcg
    10861 gactggtaat gatgaacttg ctgctaaaga tgcaatggat gctgagagtt actttactcc
    10921 tgcttggcaa gaaagccgtt cgggagtaaa agcagagcaa gttattcaaa ttgctcgtga
    10981 atttgcccaa aacgcggccg aaaatgaagg gcggagtatg gtaatcatgg gtggtggggt
    11041 caaccactgg ttcaatgccg atatgaacta tcgaaacatt attaatatgc tgatgctgtg
    11101 tggttgtgtt ggtatgactg gtggtggttg ggctcactac gttggtcaag aaaagctccg
    11161 tccacaagag ggttgggcaa atattacttt tgctaatgac tgggaaaaag gtggtgcccg
    11221 tcaaatgcaa ggtactactt ggtattactt tgcaactgat caatggcgtt atgaagaaat
    11281 tgataaccaa gctcaaaaat cacctgtttg gaagagtaaa cattcctact tacataatgc
    11341 tgattataat caaatggcaa ttcgtttagg atggttacca tcatacccac aatttgatcg
    11401 taatccgtta tcttttgcaa aagattacaa tacaactgat attaatgaaa tttcaaagaa
    11461 agttgtcgat gaattgaaga agggctcttt acattttgct gctgaagatc ctgatgctaa
    11521 ccaaaatcaa cccaaagcgt tcttcttatg gcgttcaaac ttatttgctt cttctggcaa
    11581 aggtgccgaa tactttatga aacatttatt aggcgctgaa aatggattgc ttgctaaacc
    11641 taatgatcga gttaagcccc aggatatgat ttggcgtgat aaaggagcaa ttggtaagtt
    11701 agatcttgtt gttgatatgg acttccgaat ggtttcaaca ccaatgtact ccgatgttgt
    11761 cctaccagct gctacttggt atgaaaagaa ggacctttca tcaactgata tgcatccatt
    11821 tattcaccca tttaatgcag cagttagtcc aatgtgggaa tcaaagtctg actggcaaca
    11881 attcaagctc ttggctaaga ctgtttctga aatggcaaag aaatacatgc cgggaacctt
    11941 ctatgatctt aagagcgcac cactaggaca taatactcaa ggggaaatcg ctcaaccata
    12001 cggggaaatt aaagattgga agaacggtga aacagaacca atccctggaa aaaccatgcc
    12061 ttctttaaaa ttagttaccc gtgattatac taagatctat gacaaataca tcactcttgg
    12121 ccctaatata gtaaataatt ataactataa agttgatgat caatatgatt acctcaaaga
    12181 catgaatgga attgctagtg aaggcattgg tgcaggctgt ccattacttg atgaagacga
    12241 aaaagtatgt gatgcaatct tacggatgtc aactgcttcc aatggtaaac tcgctgatcg
    12301 agcttgggaa aagaagcaag aacggactgg tgaacatttg acagatattg gtcgcggtca
    12361 tgctgatgat tcaatgtcgt ttaagcaaat cactgctcaa ccacaagaag cttatccaac
    12421 accaatcgga acttctgcta aacatggtgg agctcgctac acaccatttt cattaatgac
    12481 tgagcgaaat attcctacat ttactcttac aggtcgtcag catttctaca ttgatcatga
    12541 aattttccgt gaatttggtg aaaatatggc aacttataaa ccatccttac caccagttgt
    12601 aatggcccca ggagatgttg atgttccacc agtaaaagat gaagttacac ttaaatatat
    12661 gactcctcat ggtaaatgga atattcatac gatgtactac gataaccttg aaatgttgac
    12721 attattccgg ggtggtccaa ctacttggat tagtccccaa gatgccgata agattaaggt
    12781 aaaagataac gactggatcg aagtttataa ccgtaatggg gttgttactg cgcgggcggt
    12841 tgtttctgtt cggatgcctg aggggtcaat gtacatgtac catgcccaag ataatgaaat
    12901 ttacgaacct ctttctacca ttaccggtaa tcgtggggga tcacataatg caccgacgca
    12961 aatccacatt aagccaacac acatggttgg aggatacagc caattgagtt acggttggaa
    13021 ttactatgga ccaactggaa accaacgtga tctttatgca aatgtaagaa agttgaagaa
    13081 ggtgaactgg agtgaagatt aaagcacaaa tcagcatggt cttaaacctc gataagtgta
    13141 ttggttgtca tacctgttca gtaacttgta agaatacatg gacaaatcgt ccaggcgctg
    13201 aatacatgtg gtttaataat gttgaaacta agccaggtgt cggttatcca aaacgctggg
    13261 aagatgaaga tcaataccat ggagggtgga ctcttaattc aaaaggtaaa ttaaaattac
    13321 gtgctggaag caaattaaat aaaatcgctc ttggtaagat tttttacaat aatgatatgc
    13381 cagagttaga taactactac gaaccatgga cctatgacta taagacatta tttggtcctg
    13441 aacaaaagca ccaacccgtt gctcgtccta agtcgcaaat tactggcgaa ggaatggaat
    13501 taatcactgg tcctaactgg gatgatgact tagcgggatc aactgaatat gtccaacagg
    13561 atcctaacat gcaaaaaatt gaaggggata tcaaaaataa ctttgagcag gcatttatga
    13621 tgtatcttcc ccgattatgt gagcactgtt tgaatgcacc ttgtgtagcc tcttgtccat
    13681 caggcgcaat gtacaaacga gatgaagatg ggattgtttt agtagaccaa gaacgctgcc
    13741 ggggatggcg tttttgcatg actggatgtc catataagaa ggtctacttt aactggaaga
    13801 ctcataaggc tgaaaaatgt actttttgtt atccgcgaat tgaagaaggt caaccaacag
    13861 tttgcgccga aacctgtgtc ggtcgaattc gatatattgg tgctattcta tacgatgctg
    13921 atcgagtaga agaggcagca tcaactcctg atgagagtaa gctgtatgaa gcacaacttg
    13981 gcttattcct cgatcccaac gatcctgaag ttgtcaagca agcactcaag gatggcattt
    14041 ctgaagagat gattgaagct gcacaaaagt caccgatcta taaaatggca gtaaaagaaa
    14101 agattgcctt cccacttcat ccagaatacc ggacaatgcc aatggtttgg tatattccgc
    14161 ctctatcacc agttatgagt tactttgaag gacgggactc aataaagaat cctgaaatga
    14221 tcttcccagg aattgatcaa atgcgggtgc ctgttcaata cttggcaagt ctattaactg
    14281 ctggaaacgt tcctgtcatc aagaaagcct tatataaact tgcaatgatg cggctataca
    14341 tgcgtgctaa gactagtggt cgggattttg atagcagtaa actagaacga gttgatttaa
    14401 cagaagaacg ggcaacatca ctttatcgtt tactggcaat tgctaaatat gaagaccgct
    14461 ttgttatccc aagtagccaa aaggcagaaa tggaagatgc acaaactgaa caaggtagtc
    14521 ttggctatga tgaatgtgaa ggctgtgcat tagctcccca acacaagagt atgtttaaga
    14581 aggcagaagc tggcaaatca actaatcaga tttatgctga tagtttctat ggagggattt
    14641 ggcgtgattg attttagacg attaatagat ttaaaagata catttgccat tctttcacgc
    14701 ttgattgact atcctgagac ggaaacattt tcaccagaga ttcgccaatt attacttaca
    14761 gataacgcat tatcaactgc aacgcgggga gaattattaa gcctctttga tgaattagct
    14821 gcattatctc caatcgaagt tcaagagatg tacgctcgcc tttttgaaat gaatcgacgc
    14881 tatactcttt atatgtcata ctacaagatg actgattccc gtgaacgagg aaccatttta
    14941 gcacggttga aaatgctata tgagatgttt ggtatatcag aggcgactag tgaactttct
    15001 gattatttgc ctttattgtt agaatttcta gcatatggcg attatactaa tgatccgcgt
    15061 cgtcaggata tccaattagc attaagtgtg attgaagatg gaacttatac ccttttaaaa
    15121 aatgcagtga tagatagtga tagtccctat attcagttaa tcaggcttac acgttcatta
    15181 attggttcgt gtattaaaat ggaggtgcag gaagatgcat agtggctggt caattttctt
    15241 atgggttatt tatccatata taatgttggc atcatttttc attggaacat ttgttagatt
    15301 taaatatttc catccctcaa ttactgccaa atcaagcgaa ctttttgaaa agaaatggct
    15361 aatgatcgga agcgttactt tccacattgg aattatttta gctttctttg gtcacttctt
    15421 aggaatgttt attccagcaa gttggacagc ttattttggg atcactgaac atatgtacca
    15481 catctttggg tcattgatga tgggaattcc agcagggatc cttgcatttg tgggaattgc
    15541 gattcttact tatcgacgaa tgacttgttc tcgtgtttat aagacaagtg atatcaatga
    15601 tattattgtc gactgggctt tactgattac aattgcatta ggtctagcaa gtactattac
    15661 gggtgcattt atcgattaca attatcgaac aacgattagt ccatgggcaa gaagcctctt
    15721 tgttcttaat cctcaatggc aattgatgcg ttcagtgcca ttaatttata aaattcacgt
    15781 tctctgtgga ttagcaattt ttggttactt cccatacacc cggttggttc acgctttaac
    15841 gctaccttgg caatatattt tccgtcgttt tattgtttat cgtcgacgcg caagagttta
    15901 ttaatatata agaagatata ataaaagcat cagatttctt cacagaggaa ttctgatgct
    15961 tttatattaa tgtctttaga cctggttgag tgcgcgagca gagcgagtgc acgaaacaaa
    16021 aaaccacctg ctatgcgggt gggcgataaa aattatataa aaaaggcctc ttttgcctta
    16081 agatgtaggt gttcaagcca aagtcaataa gggaaaagag gttatataaa tatggctaat
    16141 aa
//
