LOCUS       gnlProkkaCKHDMJND_161   1607 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CKHDMJND_161.
ACCESSION   gnlProkkaCKHDMJND_161
VERSION     gnlProkkaCKHDMJND_161
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 05:01:06
            Original ID  :: gnl|Prokka|CKHDMJND_161
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 1607
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..1607
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:1607]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..1607
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..1607
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..1607
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS_motif       complement(3..62)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_1_0007"
                     /evalue="4.50E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg115_1"
                     /protein_end="535"
                     /protein_start="515"
                     /score="12.6"
                     /tool="antismash"
                     /translation="FDPERVEKTLQALIEHHDAL"
     CDS             complement(3..1607)
                     /NRPS_PKS="Domain: AMP-binding (20-297). E-value: 2.7e-68.
                     Score: 222.2. Matches aSDomain:
                     nrpspksdomains_ctg115_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (402-470). E-value: 2.6e-28. Score:
                     89.9. Matches aSDomain: nrpspksdomains_ctg115_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     237.5; E-value: 3.8e-72)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg115_1"
                     /sec_met_domain="AMP-binding (E-value: 5.5e-87, bitscore:
                     278.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.5e-20, bitscore:
                     58.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5.6e-19, bitscore:
                     54.4, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKLLLKQECISVPDSFSGDVILLDGSRTILSLPLDENDEGNPET
                     AVTAENLAYMIYTSGTTGQPKGVMVEHHALVNLCFWHHDAFSMTAEDRSAKYAGFGFDA
                     SIWEMFPTWTIGAELHVIDEAIRLDIVRLNDYFETNGVTITFLPTQLAEQFMELENTSL
                     RVLLTGGDKLKRAVKKPYTLVNNYGPTENTVVATSAEIHPEEGSLSIGRAIANTRVYIL
                     GEGNQVQPEGVAGELCVAGRGLARGYLNKEDETAKRFVADPFVPGECMYRTGDLVKWTG
                     GGIEYIGRIDQQVKVRGYRIELSEIEVQLAQLSEVQDAAVTAVKDKGGNTAIAAYVTPE
                     SADIEALKSALKETLPDYMIPAFWVTLNELLVTANGKVDRKALPEPDIEAGSGEYKAPT
                     TDMEELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRLNQHGWKLEMKDLFQHP
                     TIEELTQYVERAEGKQADQGPVEGEVILTPIQRWFFEKNFTNKHHWNQSVMLHAKKGFD
                     PERVEKTLQALIEHHDAL"
     CDS_motif       complement(123..152)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_1_0006"
                     /evalue="3.20E-05"
                     /label="NRPS-E1"
                     /locus_tag="ctg115_1"
                     /protein_end="495"
                     /protein_start="485"
                     /score="16.5"
                     /tool="antismash"
                     /translation="LTPIQRWFFE"
     aSDomain        complement(198..401)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg115_1_PCP.1"
                     /evalue="2.60E-28"
                     /label="ctg115_1_PCP.1"
                     /locus_tag="ctg115_1"
                     /protein_end="470"
                     /protein_start="402"
                     /score="89.9"
                     /tool="antismash"
                     /translation="EELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRLNQHGW
                     KLEMKDLFQHPTIEELTQYVERA"
     aSModule        complement(198..1547)
                     /complete
                     /domains="nrpspksdomains_ctg115_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg115_1_PCP.1"
                     /locus_tags="ctg115_1"
                     /monomer_pairings="Leu -> Leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(309..338)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_1_0005"
                     /evalue="5.70E-03"
                     /label="PCP_mC"
                     /locus_tag="ctg115_1"
                     /protein_end="433"
                     /protein_start="423"
                     /score="10.1"
                     /tool="antismash"
                     /translation="NFFSLGGDSI"
     CDS_motif       complement(687..752)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_1_0004"
                     /evalue="1.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg115_1"
                     /protein_end="307"
                     /protein_start="285"
                     /score="36.8"
                     /tool="antismash"
                     /translation="YIGRIDQQVKVRGYRIELSEIE"
     aSDomain        complement(717..1547)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg115_1_AMP-binding.1"
                     /evalue="2.70E-68"
                     /label="ctg115_1_AMP-binding.1"
                     /locus_tag="ctg115_1"
                     /protein_end="297"
                     /protein_start="20"
                     /score="222.2"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="VILLDGSRTILSLPLDENDEGNPETAVTAENLAYMIYTSGTTGQP
                     KGVMVEHHALVNLCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVIDE
                     AIRLDIVRLNDYFETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYTL
                     VNNYGPTENTVVATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGR
                     GLARGYLNKEDETAKRFVADPFVPGECMYRTGDLVKWTGGGIEYIGRIDQQVKVR"
     CDS_motif       complement(831..920)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_1_0003"
                     /evalue="2.10E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg115_1"
                     /protein_end="259"
                     /protein_start="229"
                     /score="48.8"
                     /tool="antismash"
                     /translation="PEGVAGELCVAGRGLARGYLNKEDETAKRF"
     CDS_motif       complement(1023..1052)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_1_0002"
                     /evalue="2.70E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg115_1"
                     /protein_end="195"
                     /protein_start="185"
                     /score="10.3"
                     /tool="antismash"
                     /translation="NYGPTENTVV"
     CDS_motif       complement(1392..1451)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_1_0001"
                     /evalue="3.50E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg115_1"
                     /protein_end="72"
                     /protein_start="52"
                     /score="34.8"
                     /tool="antismash"
                     /translation="AYMIYTSGTTGQPKGVMVEH"
ORIGIN
        1 cggagcgcgt catgatgctc gattagcgcc tgcaatgttt tctccacccg ttcaggatca
       61 aagcccttct tggcgtgaag catcaccgat tggttccagt ggtgcttgtt cgtgaagttc
      121 ttttcaaaga accagcgctg gatcggcgtc aggatgactt cgccctccac cgggccttgg
      181 tctgcctgtt tgccttcggc acgctctacg tattgggtca gctcctcgat cgtcggatgc
      241 tggaagagat ctttcatttc cagcttccag ccgtgctggt tcaagcggct cgccatttga
      301 attcctttga tggaatctcc gccaagcgag aagaaattgt cggtgacacc gacttcagac
      361 attccaagca cgtcctgcca gatgccggca agcagctctt ccatatcggt cgttggcgct
      421 ttgtattctc cgcttcccgc ttcgatgtcc ggctcaggca aggctttgcg gtccactttg
      481 ccgtttgccg taaccagaag ctcgttcagc gtcacccaga acgccggaat catgtaatcc
      541 ggcagggttt ccttcagtgc tgatttcagt gcttctatgt cagctgattc cggtgtgaca
      601 tacgccgcga tcgctgtgtt gccgccttta tctttgacag ctgtcaccgc cgcatcctgc
      661 acctcagaaa gctgggcgag ctggacttca atttctgata gctcgatccg gtagccgcgg
      721 accttgacct gctggtcgat ccggccgatg tattcgatgc cgccgcccgt ccatttcacc
      781 aaatcgccgg tgcggtacat gcactcaccc ggcacaaacg gatcagcgac aaaccgcttc
      841 gcggtttcgt cttctttatt cagatagcct cgcgccagtc cgcgtcccgc cacgcaaagc
      901 tctccggcta cgccttccgg ctgcacctga ttgccctcgc cgagaatgta tactctcgta
      961 ttggcaatgg cccttccgat ggaaagcgag ccttcctccg gatggatttc tgcgcttgtg
     1021 gcaacgaccg tgttttctgt cggcccgtag ttgttgacga gtgtgtacgg ctttttcact
     1081 gcccgcttca gcttgtctcc tccagtgagc aatacgcgaa gtgatgtgtt ctcaagctcc
     1141 atgaactgtt ccgcaagctg tgtcggcagg aacgtgatcg ttacgccgtt cgtttcaaaa
     1201 taatcgttca ggcggacgat atcgaggcgg atcgcttcat caatgacgtg aagctcagcg
     1261 ccgatcgtcc aagtcgggaa catctcccaa atggaagcgt caaatccaaa gcccgcgtac
     1321 ttcgcactgc ggtcctccgc tgtcatgctg aacgcgtcgt ggtgccagaa gcacaggttc
     1381 acaagcgcat ggtgctcgac catgacaccc ttcggctgtc cggtcgttcc agatgtgtaa
     1441 atcatgtacg ccaagttctc cgcggttaca gccgtctctg gatttccctc gtcgttttca
     1501 tcaagcggca ggcttagaat cgtgcggctt ccgtcgagaa gaataacgtc tcctgagaag
     1561 ctatccggca ctgaaatgca ttcttgcttc aagagaagct tcgcgcc
//
