LOCUS       c00012_gnlPro..        23237 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CKHDMJND_25.
ACCESSION   c00012_gnlPro..
VERSION     c00012_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 05:33:47
            Original ID  :: gnl|Prokka|CKHDMJND_25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 166447
            Orig. end    :: 189684
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23237
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[176447:179684]"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13237
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
     cand_cluster    1..23237
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /kind="single"
                     /product="fatty_acids-unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23237
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="fatty_acids-unassigned"
                     /region_number="1"
                     /rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /tool="gutsmash"
     CDS             347..1192
                     /locus_tag="ctg12_188"
                     /transl_table=11
                     /translation="MTSKKERLDVLLVERGLAETREKAKRAIMAGIVYSNENRLDKPGE
                     KIDRDLPLTVKGNPLRYVSRGGLKLEKALKEFPVSVKDKIMIDIGSSTGGFTDCALQNG
                     AKQSYAVDVGYNQLAWKLRQDERVVVMERTNFRYATPADFTKGMPEFATIDVSFISLRL
                     ILPVLRTLLVPGSDCMALVKPQFEAGRESVGKKGIVRDPKVHADVLKRMISFSAAEGYI
                     CKGLSFSPITGGDGNIEFLLHLHWPGEGQDGQELPEEEIMRVVEEAHKTLKEKKADVPE
                     "
     CDS             1290..1739
                     /locus_tag="ctg12_189"
                     /transl_table=11
                     /translation="MNKGQRHIKIREIITSNEIETQDELVDMLKQDGYKVTQATVSRDI
                     KELHLVKVPTNNGSYKYSLPADQRFNPLSKLKRALMDAFVKIDSASHMIVLKTMPGNAQ
                     AIGALMDNLDWDEMMGTICGDDTILIICRTPGDTEGVKNRLLELL"
     CDS             1772..3502
                     /locus_tag="ctg12_190"
                     /transl_table=11
                     /translation="LLAELSIKNFAIIEELTVSFERGLTVLTGETGAGKSIIIDAISLL
                     VGGRGSSEFVRYGEAKAELEGLFLLESGHPVLGVCAEQGIDVSDEMIVMRRDISTSGKS
                     VCRVNGKLVTIASLREIGRLLLDIHGQHDNQLLMEDENHLQLLDKFAGAEVESALKTYQ
                     EGYQRYMKLLKKLKQLSESEQEMAHRLDLIQFQLEEIESAKLELNEDEQLQEERQEISN
                     FEKIYESLQNAYNALRSEQGGLDWVGMASAQLEDISDINEPLKKLSESVSNSYYLLEDA
                     TFQMRNMLDELEFDPERLNYIETRLNEIKQLKRKYGATVEDILEYASKIEEEIDQIENR
                     DSHLQSLKKELDSVGKDVAVEAANVSQIRKTWAKKLADEIHRELKSLYMEKSTFDTEFK
                     VRTASRNEEAPLVNGQPVQLTEQGIDLVKFLISTNTGEPLKSLSKVASGGELSRVMLAI
                     KSIFSSQQDVTSIIFDEVDTGVSGRVAQAIAEKIHKVSIGSQVLCITHLPQVAAMADTH
                     LYIAKELKDGRTTTRVKPLSKQEKVAEIGRMIAGVEVTDLTKRHAKELLKQADQVKTTG
                     "
     CDS             3677..4954
                     /locus_tag="ctg12_191"
                     /transl_table=11
                     /translation="MPDNIRKAVGLVLLVSLLSVGLCKPLKEYLLIPTQMRVFETQTQA
                     IETSLSVNAQTPESSEAFTVKKDPHEIKVTGKKSGKSELVYDLAGFPIKKTKVHVLPDL
                     KVIPGGQSIGVKLHSVGVLVVGFHQINTSEGKKSPGETAGIESGDIIIEMNGQKIEKMN
                     DVAPFIQKAGKTGESLDLLIKRDKQKIKTKLIPEKDEGEGKYRIGLYIRDSAAGIGTMT
                     FYEPKTKKYGALGHVISDMDTKKPIVVENGEIVKSTVTSIEKGTGGNPGEKLAFSSERK
                     TIGDINRNSPFGIFGTLHQPIQNNISDQALPVAFSTEVKKGPAEILTVIDDDKVEKFDI
                     EIVSTTPQKFPATKGMVLKITDPRLLKETGGIVQGMSGSPIIQNGKVIGAVTHVFVNDP
                     TSGYGVHIEWMLSEAGIDIYGKEKAS"
     CDS             5230..6033
                     /locus_tag="ctg12_192"
                     /transl_table=11
                     /translation="VEKIKVCVADDNRELVSLLSEYIEGQEDMEVIGVAYNGQECLSLF
                     KEKDPDVLVLDIIMPHLDGLAVLERLRESDLKKQPNVIMLTAFGQEDVTKKAVDLGASY
                     FILKPFDMENLVGHIRQVSGNASSVTHRAPSSQSSIIRSSQPEPKKKNLDASITSIIHE
                     IGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEV
                     AWSRGNIDSISSLFGYTVSMTKAKPTNSEFIAMVADKLRLEHKAS"
     CDS             complement(6500..7648)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Oxidored_FMN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_193"
                     /sec_met_domain="Oxidored_FMN (E-value: 4e-123, bitscore:
                     405.0, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRIQTKEDDQMNPKYKPLFEPFTFKSGVTIDNRIAVAPMTHYASN
                     EDGTISEAELDYIIPRSKEMGMVITACANVTPDGKAFPGQPAIHDDSNIPGLKKLAQAI
                     QAQGAKAVVQIHHGGIECPSELVPQQDVVGPSDVFDNGKQIARALKEEEVENIVKAFGE
                     ATRRAIEAGFDGVEIHGANGYLIQQFYSPKTNQRTDRWGGSDEKRLAFPLAIVDEVKKA
                     ASEHAKGAFLVGYRLSPEEPETPGLTMTETYTLVDALGDKELDYLHISLMDVNSKARRG
                     ADPTRTRMDLLNERVGNKVPLIAVGSIHSADDALAVIENGIPLVAMGREILVDPDWTVK
                     VKEGREKQIETVIKGTDKEKYHLPEPLWQAIVNTPGWVPYKD"
     CDS             8140..8436
                     /locus_tag="ctg12_194"
                     /transl_table=11
                     /translation="VKQTVLLLFTALFLSGCSVASADDSVPRFTEEGKYIGSADPHTIA
                     VSLNGEETMIQVPKDKREECESLPDQTHVLVKYTKKDNGTLQLEDIQLRKNSS"
     CDS             8462..9064
                     /locus_tag="ctg12_195"
                     /transl_table=11
                     /translation="MLLRSLALCGLALTLAPCAQAAELIVYIDAGHGGEDSGAVGNGLF
                     EKDINLAVSEHVTDKLKEEGANPVASRSDDHFLTLEERVAKASANQADLFVSIHVNSGV
                     SSASGTETYFQSDYERENSRRLASDIQSQLVSSLQTRDRGVKESDFYVITYSQMPSVLA
                     ELGFITNSSDADKLGSEEYQQKAADAIVNGIDSYYDQ"
     CDS             9143..9874
                     /locus_tag="ctg12_196"
                     /transl_table=11
                     /translation="MTKIFAHRGASGQFPENTMLAFEKGIEAGADGIELDVQLTKDGRI
                     VVIHDERLNRTTSLKGFVKDTAYDEVKTANAAAGHDQAYSDIKVPLLEDVLSWAVKKDF
                     LINIELKNSVIRYEGMEEKVLEAVKRFNVEERVILSTFNHDSLALCARLAPHIERAVLT
                     SDVLYQADRYIASIPASGYHPKLNSPGVTDEVLKKMRNSSIKVRPYTVNRPEDMKRLIE
                     AGADGMFTDFPEKASALLKNE"
     CDS             10001..11182
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_197"
                     /sec_met_domain="Thiolase_N (E-value: 5.3e-103, bitscore:
                     337.9, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 1.2e-50, bitscore:
                     164.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKTVIVSAARTPFGKFGGVLKEVKAAELGGIVMKEALQRAGVSG
                     DDVEGNVMGMVVQAGSGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRA
                     QDADILVAGGMESMSNIPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGNT
                     AAMEYAISRREQDEWALRSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIRR
                     DTSLDQLAKLAPIYASDGSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFST
                     TGMPAHELAAAPGFAINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVNV
                     NGGAIALGHPIGASGARILMTLVYELKRRGGGLGVAAICSGAAQGDAVLVQVH"
     CDS             11207..12070
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_198"
                     /sec_met_domain="HCDH (E-value: 2.6e-39, bitscore: 127.8,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 1.2e-68, bitscore: 224.6,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKQIMVAGAGQMGSGIAQTAAGAGFYVRMYDVNPEAAEAGLKR
                     LKKQLARDAEKGKRTETEVKSVISRISISQTLEEAEHADIVIEAIAENMAAKTEMFKTL
                     DRICPPHTILASNTSSLPITEIAAVTNRPQRVIGMHFMNPVPVMKLVEVIRGLATSEET
                     ALDVMALAEKMGKTAVEVNDFPGFVSNRVLLPMINEAIYCVYEGVAKPEAIDEVMKLGM
                     NHPMGPFALADFIGLDTCLSIMEVLHSGLGDSKYRPCPLLRKYVKAGWLGKKSGRGFYD
                     YEEKTS"
     CDS             12098..13237
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_199"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.6e-57, bitscore:
                     186.2, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.4e-29, bitscore:
                     94.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.3e-39, bitscore:
                     128.6, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LHVTQEQIMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGE
                     HGLMGIPVPEQYGGAGADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQ
                     KMKYIPNLASGDHLGAFALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADI
                     YITFALTAPDQGRHGISAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANL
                     LGKEGDGFHIAMANLNVGRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISF
                     KLADMATRAEAARHLVYHAADLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYG
                     YMKDYPVERLLRDAKVTQIYEGTNEIQRLIISKYLLGGT"
     CDS             13271..14389
                     /locus_tag="ctg12_200"
                     /transl_table=11
                     /translation="MEEKQHYSPGLDGVIAAETHISYLDTQSSQILIRGYDLIELSETK
                     SYLELVHLLLEGRMPEESEMETLERKINSASSLPADHLRLLELLPEDTHPMDGLRTDLS
                     ALAGYDRQIDDRSPSANKERAYQLLGKMPALTAASYRIINKKEPILPLQTLSYSANFLY
                     MMTGKLPSSLEEQIFDRSLVLYSEHEMPNSTFAARVIASTHSDLYGALTGAVASLKGNL
                     HGGANEAVMYLLLEAKTTSDFEQLLQTKLKRKEKIMGFGHRVYMKKMDPRALMMKEALQ
                     QLCDKAGDHRLYEMCEAGERLMEKEKGLYPNLDYYAAPVYWMLGIPIPLYTPVFFSART
                     SGLCAHVIEQHANNRLFRPRVSYMGPRYQTKS"
     CDS             14404..15822
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MmgE_PrpD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_201"
                     /sec_met_domain="MmgE_PrpD (E-value: 5.5e-152, bitscore:
                     500.3, seeds: 231, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKTDRVIVEITDYVLEKEITSAEAYTTAGHVLLDTLGCGILALR
                     YPECAKLLGPIVPGTTVPNGSKVPGTSYVLDPVRAAFNIGCMIRWLDYNDTWLAAEWGH
                     PSDNLGGILAAADYVSRVRLSEGKEPLTVRDVLEMMIKAHEIQGVLALENSLNRVGLDH
                     VLFVKVATTAVAAKLLGGGREEIKNALSNAWIDNAALRTYRHSPNTGSRKSWAAGDATS
                     RGVHLALMSLKGEMGYPTALSAPGWGFQDVLFNKKEIKLARPLDAYVMENVLFKVSYPA
                     EFHAQTAAECAVILHPQVKNRIDEIDRVVIRTHESAIRIIDKKGPLHNPADRDHCLQYI
                     TAIGLLFGDITAQHYEAETASDPRIDKLRDKMEVTENKTYTEDYLKPDKRSISNAVQVH
                     FKDGTSTEMVECEFPLGHRFRREEAVPKLLEKFSDNLKTHFPVKQHKHIYERCTSYETL
                     QTMRVNEFVDMFCM"
     CDS             15840..16745
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_202"
                     /sec_met_domain="PEP_mutase (E-value: 6e-55, bitscore:
                     180.3, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWIVNKQSSQEELAGRFRKLMSAPDILQIPGAHDGMAALLAKEA
                     GFSAIYLSGAAYTASRGLPDLGIITSAEIAERAKDLVRAADLPLLVDIDTGFGGVLNAA
                     RTAREMLEARVAAVQIEDQQLPKKCGHLNGKQLVPIKEMSQKIKAIKQAAPSLIVVART
                     DARAQEGLDAAIKRSEVYIEAGADAIFPEALQAENEFRQFAERISVPLLANMTEFGKTP
                     YYRADEFEDMGFHMVIYPVTSLRSAAKACERMFGLMKEHGSQKEGLHDMQTRKELYDTI
                     SYYDYEALDKTIAKTVLPDE"
     CDS             17176..19254
                     /locus_tag="ctg12_203"
                     /transl_table=11
                     /translation="MQKVLIVGAGKRGTALLHILIKTAIIDIIAVVDKDPEAPGLKEAE
                     QYGIAVSSDWKPYIQQKPDIVIHTTGDQAVFDELLQRKHEDTIVMPGKMAYIVFQLMEE
                     KQHLIQMLKEQTYKYDRIFNSTHDGMIFIDINEEIILFNHMAEKMVEKKREEVIGRPIK
                     EVIPSTKLPRILKTRVPEYNQKQLLGDHLQIVTTRLPIIDEGGRLLGALCVFKDITDAV
                     ELAEEVTNLKQVRTMLEAIIQSSDEAISVVDENGIGLLINKAYTKMTGLSEKEVIGKPA
                     NTDISEGESMHLKVLETRRPVRGVRMKVGPNEKEVIVNVAPVIVDGILKGSVGVIHDVS
                     EIKMLTAELNRARQIIRTLEAKYTFDDIIGKSEQMLVALEQAKLGAKTPATILLRGESG
                     TGKELFAHAIHNESDRKYNKFIRVNCAALSENLLESELFGYEDGAFSGAKRGGKKGLFE
                     EANNGSIFLDEIGELTQNMQAKLLRVLQEKEIVRVGGTKAIPVNVRVIAATNVNIEKAM
                     ADGTFREDLYYRINRYPISIPPLRQRLEDIEALSVRLIQKINRDYGRNVKGLSQQALRA
                     LSAYHWPGNVRELENVLGRAMIFLNPHMEWIEKDHLPVFELEQKENDTDQGTGFNIPDI
                     EGEKLSVAVEKFEAHLIQQTLEKHHFNRTKTAKALGVSIRNLYYKMDKYGLANEGMQ"
     CDS             19379..20278
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTA_PTB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_204"
                     /sec_met_domain="PTA_PTB (E-value: 2.9e-50, bitscore:
                     165.4, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKDLIGKASMHKNKTIAVAHAEDEEVIRAVKLAAEHLSARFLL
                     TGDSKKLNELTSSMQGHQVEIVHADTPEESAKLAVRAVHHKTADVLMKGNVPTSVLLKA
                     VLNRQEGLRSSSVLSHVAVFDIPDFDRLMFVTDSAMNIAPSLEELRQILQNAVHVAHAV
                     GNNMPKAAALAAVETVNPKMEATVNAAALAQMYKRGQIKGCIVDGPLALDNAVSQIAAA
                     QKKISGDVAGNADILLVPTIEAGNILYKSLIYFAKASVAAVITGAKAPIALTSRADSAE
                     NKLYSIALAICASEEYTH"
     CDS             20290..21384
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ELFV_dehydrog"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ELFV_dehydrog_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_205"
                     /sec_met_domain="ELFV_dehydrog (E-value: 2.6e-11, bitscore:
                     37.7, seeds: 97, tool: rule-based-clusters)"
                     /sec_met_domain="ELFV_dehydrog_N (E-value: 2.9e-30,
                     bitscore: 98.9, seeds: 410, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELFKYMEKYDYEQLVFCQDEQSGLKAIIAIHDTTLGPALGGTRM
                     WTYENEEAAIEDALRLARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEEMFRAFGRYIQ
                     GLNGRYITAEDVGTTVEDMDIIHDETDYVTGISPAFGSSGNPSPVTAYGVYRGMKAAAK
                     AAFGTDSLEGKNIAVQGVGNVAYNLCRHLHEEGANLIVTDINKQSVQRAVEDFGARAVD
                     PDDIYSQDCDIYAPCALGATINDDTIKQLKAKVIAGAANNQLKETRHGDQIHEMGIVYA
                     PDYVINAGGVINVADELYGYNAERALKKVEGIYGNIERVLEISQRDGIPAYLAADRLAE
                     ERIERMRRSRSQFLQNGHSVLSRR"
     CDS             21409..22494
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Butyrate_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_206"
                     /sec_met_domain="Butyrate_kinase (E-value: 1.9e-154,
                     bitscore: 507.5, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLHDEKRILTINPGSTSTKIGVFHNERSIFEKTLRHNIEELQRFD
                     RIIDQYEFRKNHILETLHEQGINISKFDAVCARGGLLRPIEGGTYVVNDEMIEDLKSGY
                     AGQHASNLGGIIAREIADGLNIPSYIVDPVVVDEMSVLAKVSGMPEIERKSIFHALNQK
                     AVARKAAASLGKRYENMKMIITHMGGGITIGVHDRGRVVDVNNGLHGEGPFSPERAGTV
                     PAGDLVDLCFSGEYTKEEIMKKLVGTGGLLGYLGTNDAVKVEQMIQGGDEKARFIYDAM
                     AYQVAKEIGAASAALKGEVEAIVLTGGLAYGKSFVSAIRSYIDWISDVLVYPGENELQS
                     LAQGALRVLQGEEQSKQYRIE"
ORIGIN
        1 aagcagccga agagctgcag aaagaaggcc tttccgtgcg cgttgtgaat gcgcgtttta
       61 ttaagccgat tgatgaaaag atgatgaaga gtatcctaaa agaaggcttg ccaattttaa
      121 caattgaaga agcggtctta gaaggcggtt tcggaagctc gattttagaa ttcgctcatg
      181 atcaaggtga atatcatact ccgatcgaca gaatgggtat acctgatcgg tttattgaac
      241 acggaagcgt aacggcgctt cttaaggaaa ttggactgac aaaacagcag gtggcaaatc
      301 gtattagatt actgatgccg ccaaagacac acaaaggaat tggatcatga cgtcaaagaa
      361 agaacgatta gatgtattat tagtggaaag agggctggcg gaaacgcgtg aaaaagccaa
      421 aagagccatt atggcgggga tcgtctattc aaacgaaaac cgcttggaca agcctggaga
      481 aaaaattgac cgcgaccttc cgttaaccgt taaaggaaac ccgctgaggt atgtgagcag
      541 gggcggctta aagctcgaaa aagcgttgaa ggaatttccc gtctctgtca aggataaaat
      601 tatgattgat attggctcct ccaccggcgg ttttacggac tgcgctttgc aaaatggagc
      661 taaacagtca tacgctgtgg atgtaggcta taatcagctt gcgtggaagc tcagacagga
      721 tgaacgggtc gtcgtgatgg aacggacgaa ctttcgttat gcaacaccgg cagactttac
      781 aaagggcatg ccggagtttg ccacaattga tgtatccttt atttcactgc ggctcatcct
      841 gcctgtccta aggactttgc tcgtaccggg cagcgactgc atggctctag ttaagcctca
      901 gtttgaagcg ggacgggaat ccgtcggcaa aaaagggatt gtcagagatc ctaaagtgca
      961 tgctgatgtg ctcaagcgaa tgatcagttt ttctgccgct gaaggctata tatgtaaagg
     1021 cttgtcattt tctccaatca ctggaggaga cggaaatatt gagtttctcc ttcatttgca
     1081 ttggccggga gagggacagg atggccagga gctgccggaa gaagagatca tgcgcgttgt
     1141 agaagaagca cataagacgt taaaagaaaa aaaagcagat gtaccggaat aatagggcgc
     1201 tattattcct tttttctgca ttcatgtaca atgtgcagag aatcatataa cataaaagaa
     1261 cagataagct tggaaataga ggtgcttaca tgaacaaagg ccagaggcat attaaaatca
     1321 gagagatcat tacaagcaat gaaatcgaaa cgcaggatga attggtcgac atgctgaagc
     1381 aggatggata caaagtaacg caggccacgg tatcacggga tattaaagaa cttcaccttg
     1441 taaaagtgcc tacaaataat ggttcttaca aatacagtct tccggcggac cagcgtttca
     1501 atccgctgtc aaagctaaag cgggcattga tggacgcatt tgtgaaaata gactcagcaa
     1561 gccatatgat tgtgctgaaa acgatgccgg gcaatgccca ggcaatcggg gcgctgatgg
     1621 acaatttgga ctgggatgaa atgatgggga ccatttgcgg agatgacacg attttaatta
     1681 tttgccggac tcctggagat acagagggtg taaaaaacag actgcttgaa ctgctgtaag
     1741 aatctaacaa agataagagg tgtaatgctg tttgttagct gaactatcga ttaaaaactt
     1801 tgccattatt gaggaactga cggtttcttt tgaacgcggg cttacggttt taacaggaga
     1861 aaccggagcc ggcaaatcca tcatcataga tgccatttct cttttagtcg gaggtcgcgg
     1921 atcatctgaa tttgttagat atggggaagc aaaagccgaa cttgaagggc tgtttctgtt
     1981 ggagagcggc catcctgttt taggcgtatg cgctgagcag ggaatcgacg tttcagacga
     2041 aatgatcgtc atgagaaggg atatcagcac gagcgggaaa agcgtttgcc gtgtcaatgg
     2101 caagcttgtc acgattgcct cgctaagaga gatcggcagg cttttattag atattcacgg
     2161 gcagcacgat aaccagctgt taatggaaga cgaaaatcat ctccagcttt tggacaagtt
     2221 tgccggggcc gaagtggaaa gcgcgctcaa aacgtatcag gaagggtacc agcggtatat
     2281 gaagctgctc aaaaagctta agcagctttc tgaaagcgaa caggaaatgg cccatcgtct
     2341 tgatcttatt caatttcagc tcgaagaaat cgaatcggca aagcttgagc ttaacgaaga
     2401 tgaacagctc caagaagagc gccaggaaat ttcaaacttt gagaagatat atgaatcgct
     2461 gcaaaatgca tataacgcgc ttcgcagtga gcagggcgga ttggactggg tcggaatggc
     2521 atcagcgcag cttgaagata tctctgatat taacgaaccg ctgaaaaaac tgtctgaaag
     2581 tgtttcgaac tcctactatt tgcttgagga tgccacattt cagatgagaa atatgctgga
     2641 tgagcttgaa tttgatccgg aacgcctgaa ctatattgag acacgactta atgaaatcaa
     2701 acagctgaaa cgaaaatacg gtgccactgt tgaagacatt ttggaatatg cttctaaaat
     2761 tgaagaagag attgaccaaa ttgaaaacag ggacagccac cttcaaagct tgaaaaagga
     2821 gcttgactcc gtcggcaaag atgtcgcagt ggaagcggca aatgtgtcac aaatccgaaa
     2881 aacatgggcg aaaaagctgg ctgatgagat tcatcgggaa ttaaaaagcc tgtacatgga
     2941 aaaatcaact tttgatacgg aatttaaggt cagaacagcg tcacgcaatg aagaggctcc
     3001 gcttgtaaac ggccagcccg ttcagctgac tgaacaaggg attgacctgg tgaagttttt
     3061 aatttcaacc aatacaggtg agccgctgaa atccctttcg aaagtcgctt caggtggaga
     3121 gctgtcacgg gtgatgcttg ccataaaaag cattttttcc tcacagcagg atgtgacatc
     3181 gatcattttt gatgaggttg atactggtgt aagcggcagg gtcgcacagg caatcgcaga
     3241 gaagatccat aaggtgtcaa taggatcaca agtgctgtgc attacacacc tgcctcaggt
     3301 ggctgccatg gcggatacgc atctttatat tgcgaaggag ttaaaagacg gcagaacgac
     3361 gacacgtgtc aagccgctct ctaagcagga aaaggtagcg gaaatcgggc gcatgattgc
     3421 aggtgtcgaa gtaaccgact taacgaaacg ccatgcgaaa gaacttttaa aacaagcgga
     3481 tcaagtcaaa acaactgggt aagctgcgcg agaagcgcag cttatttttt tcgtgcacat
     3541 ccattcgttc atcagtatat ccaatgtttt tcttcatatg acagttataa ataagccgtc
     3601 agaaggcaaa attaaatgat gtagcagcaa gtcataaaga aggtgtggga taggagcgag
     3661 gagagtgaag tagtgaatgc ccgataacat cagaaaagca gtaggtttag ttctccttgt
     3721 ttcgttatta agtgtaggtt tatgcaaacc gctaaaagaa tatttactga ttccaacgca
     3781 aatgagagta tttgaaaccc aaacacaagc gattgaaaca agtttatcgg taaacgctca
     3841 gacaccagaa tcctcagaag cgtttacagt aaagaaagat ccgcatgaaa tcaaggtgac
     3901 gggcaaaaaa tcaggtaagt cagaattggt atatgatctt gccggatttc caattaaaaa
     3961 aacaaaagtg catgttcttc ctgatttaaa ggttatacct ggcggacaat caatcggtgt
     4021 aaaacttcat tccgtcggtg ttcttgtcgt cggatttcat caaatcaata caagtgaagg
     4081 caaaaaatct ccgggagaaa cggccggaat tgaatcgggc gacatcatta ttgagatgaa
     4141 tgggcagaaa attgaaaaaa tgaatgatgt agccccattt attcaaaagg ctgggaaaac
     4201 tggtgaatct ttagacttac tgatcaaacg tgacaaacag aaaatcaaaa cgaagctgat
     4261 cccagaaaag gatgaaggag aaggcaaata cagaatcggg ttatatatca gagattctgc
     4321 tgccggcatc ggcactatga ccttttatga accgaaaaca aaaaaatacg gagcacttgg
     4381 ccacgtgatt tccgatatgg acacaaagaa accaattgta gtggagaatg gagaaatcgt
     4441 taaatccacc gtaacatcaa ttgaaaaagg gacaggcggt aatccgggag aaaaactggc
     4501 attttcctca gaacgcaaaa cgatcgggga tattaacaga aacagcccgt ttgggatttt
     4561 cggcacactg catcagccga ttcaaaacaa catatcagat caagcattgc cggttgcgtt
     4621 ttctaccgaa gtcaaaaaag ggccggctga aattttaacg gttattgatg atgacaaagt
     4681 agaaaaattc gatattgaaa tcgtcagcac aacgccgcaa aaattccctg cgacaaaagg
     4741 aatggtgttg aaaattaccg atccaagact gttgaaagaa acaggaggca tcgtacaggg
     4801 gatgagcgga agcccgatca ttcaaaatgg aaaagtgatc ggtgctgtca cccatgtatt
     4861 cgtaaatgac ccgacaagcg gctacggtgt tcatattgaa tggatgctgt cagaagcagg
     4921 aatcgatatt tacggaaaag aaaaagcaag ctgactgccg gagtttccgg cagttttttt
     4981 attttgatcc ctcttcactt ctcagaatac atacggtaaa atatacaaaa gaagattttt
     5041 cgaaaaattc acgtttcctt gtttgtcaaa tttcattttt agtcgaaaaa cagagaaaaa
     5101 catagaataa caaagatatg ccactaatat tggtgattat gattttttta gagggtatat
     5161 agcggttttg tcgaatgtaa acatgtagca agggtgaatc ctgttaacta catttgggga
     5221 ggaagaaacg tggagaaaat taaagtttgt gttgctgatg ataatcgaga gctggtaagc
     5281 ctgttaagtg aatatataga aggacaggaa gacatggaag tgatcggcgt tgcttataac
     5341 ggacaggaat gcctgtcgct gtttaaagaa aaagatcccg atgtgctcgt attagatatt
     5401 attatgccgc atttagacgg acttgcggtt ttagagaggc tgagggaatc agatctgaaa
     5461 aaacagccga atgtcattat gctgacagcc tttggacagg aagatgtcac gaaaaaggcc
     5521 gtcgatttag gcgcgtccta ctttattctc aaaccgtttg atatggaaaa ccttgtcggc
     5581 catatccgcc aggtcagcgg aaatgccagc agtgtgacgc atcgtgcgcc atcatcgcaa
     5641 agcagtatta tacgcagcag ccagcctgaa ccaaagaaga aaaatctcga cgcgagcatc
     5701 acaagcatta tccatgaaat cggcgtccca gcccatatta aaggctatct ctatctgcgc
     5761 gaagcaatct caatggtata caatgacatc gaattgctcg gcagcattac aaaagtcctc
     5821 tatccggaca tcgccaaaaa attcaacaca accgcaagcc gtgtagaaag agcgatccgc
     5881 catgcaattg aagtggcatg gagcagagga aatattgatt ccatttcctc gttgttcggt
     5941 tatactgtca gcatgacaaa agctaaaccg acaaattcgg agttcatcgc aatggttgca
     6001 gataagctga gattagaaca taaggcttct taaacatgag cttattaagt ggtcgttaaa
     6061 tcaaacgtct tttatttatt agtttgcgct gataaatagg aggcgttttg ttttggggac
     6121 atttgttagt atgggagaag aatattaagt atccgcatat agtaaaggat aggtttgaaa
     6181 agtaaggaaa gcaaatggcg gtattacctg cactcttggt ccattcatac atcttatagg
     6241 attacgaagc aggatcgacc ctagatgtgt ccgttataaa atgaaacctt tctcctgcaa
     6301 aatcgtaagt aaggcgtatt catgtaaaaa ggagacgtac gaatgaaaaa gaaaaaaagc
     6361 aagaaagcgt gaggggtttt tcctggattt tcttttcgaa gttggtgggg agctctttct
     6421 tttgctgttt agatgtgtac acaaactatt tatataaagg gaaaaaagac tgccgaatcg
     6481 tttcggcagt ctttgcacat taatctttat aaggcaccca gcctggcgtg ttcacaattg
     6541 cttgccatag cggttcaggc aaatgatatt tttctttatc tgtgcctttg atcactgttt
     6601 cgatttgctt ttcacggcct tcttttactt ttaccgtcca gtcagggtca actagaattt
     6661 cgcgtcccat agcgactagc ggaataccgt tttcgatgac ggcaagcgcg tcatcagcgg
     6721 aatggatgga accgacggcg atcagcggca ctttgtttcc gacacgttca ttcaataagt
     6781 ccatgcgtgt gcgagtcgga tctgcaccgc ggcgcgcttt tgagttcacg tccatcagtg
     6841 agatatgaag ataatccaat tctttatccc ctaaagcatc aacaagcgta taagtttcag
     6901 tcattgtcaa tcccggtgtc tcaggttctt ccggagacag acggtagccg actaagaacg
     6961 cacccttcgc atgttctgaa gcggcttttt tcacttcatc gacaatagcg agcgggaagg
     7021 ctaatcgttt ttcatcgctt cctccccagc gatccgtgcg ctgattggtt ttcggagaat
     7081 aaaactgctg aattaagtag ccgtttgcac cgtgaatttc gacaccgtca aagccggctt
     7141 caatggcgcg tcttgtcgct tctccaaacg ccttcacaat gttttccact tcttcttctt
     7201 ttaatgcgcg agcaatttgt ttgccgttat caaacacgtc acttggcccc acaacatcct
     7261 gttgaggaac gagctcagac gggcattcga tgccgccgtg atgaatttgt acaacggctt
     7321 tagcgccttg tgcctgaatg gcttgtgcta acttttttaa acctggaatg ttggaatcgt
     7381 catggatggc cggctgcccg gggaatgctt ttccgtccgg tgtaacattt gcgcaggctg
     7441 taatcaccat tcccatctct tttgaacggg ggatgatgta gtcgagctcc gcttcagata
     7501 ttgtaccgtc ttcattagaa gcgtaatgag tcatcggtgc tactgcgatc cggttgtcga
     7561 ttgtaacgcc gcttttaaac gtaaatggtt caaaaagtgg cttatactta ggattcattt
     7621 gatcatcttc tttcgtttgg attcgcacat attctagcct atatgtaaaa attaatgcaa
     7681 ttgatctgct ttaccgactg aatatcttga gtgcagagtg atgttttcgc cgctcttttt
     7741 cggggccttt gtagccgccg ctgatttggt ggccgatgga gcatgtgatg acagctgccg
     7801 ccagcagcag aacgaatttt ttcatggttt taccttcttt caataaagta aaaggttacg
     7861 cttggctgac ccacccgtca aacgatttgc tcaccctatt ctcaaatttt ttaaaatgaa
     7921 taaaaagttg cttctttccg ctaatttttt ctaattggtg cctcaattag agccatcctc
     7981 atagacaaat ctgctcgtta tctttctaac aacaggaaat gatcgggtcg tatagccctt
     8041 ttgaaaatca tggaacttgc tcgcctgcat tcgcgttgtc tttacaaatt cgccattctg
     8101 gtcaaagata aaagccaaac atcaggaaga ggtggtcatg tgaaacaaac ggttcttttg
     8161 ctgtttactg cgctctttct ttcggggtgc agtgttgcaa gtgcggatga ctcagtgcca
     8221 aggtttaccg aagagggaaa atacattggc tcggctgatc ctcatacgat tgcggtttct
     8281 cttaatggag aagaaaccat gatacaagtt ccgaaggata aacgtgaaga atgtgaatca
     8341 ctgccagatc agacacatgt cctggtgaaa tatacaaaga aggataatgg aactttacag
     8401 ctagaagata ttcagctgcg aaagaactcg tcataaaaag accggaggga gtaagttgag
     8461 aatgttattg aggagcttgg cgctgtgcgg attggctttg acgctcgcgc cttgtgcaca
     8521 ggcagcagag ctgatagtgt atattgatgc cggacacggc ggtgaagaca gtggagctgt
     8581 cggaaacggg ctctttgaaa aggatattaa tttggctgtc tcagagcatg tgacagacaa
     8641 actaaaagag gagggagcca atcctgttgc atcccggtct gacgatcatt ttctgacctt
     8701 ggaggaaaga gtggctaagg caagtgccaa tcaggctgac ctttttgtca gcattcatgt
     8761 gaattctggg gtttcttcag cttcaggaac agaaacgtat tttcaatctg attatgaaag
     8821 ggagaacagc cggcgtctgg catccgatat tcagtcacag ctcgtttctt ccttacaaac
     8881 gagagacagg ggcgtgaaag aatcagactt ttacgtcatt acatattcac aaatgccaag
     8941 tgtgttggcg gagcttgggt ttatcacgaa cagctctgac gcggacaagc tgggaagtga
     9001 agaataccag caaaaggccg cagatgcgat tgtcaacggc attgattctt attatgatca
     9061 gtagattgat acagccttaa tcctagagtg gagccgacaa aataagtata atggagaaaa
     9121 ctttagggtt tgaggtgaaa tgatgacaaa gatttttgcc caccgggggg catcaggtca
     9181 atttcccgaa aatacaatgc ttgcatttga aaaaggaatt gaagccggag cggatgggat
     9241 agagcttgat gtacagctga cgaaagacgg acgcattgtt gtgattcatg atgaaagact
     9301 taatcgcacg acatcactta aaggattcgt gaaggataca gcctatgatg aggtgaagac
     9361 tgcgaatgcg gccgctggtc acgatcaagc gtacagcgat ataaaagtgc cgctgctaga
     9421 agatgtgctc tcgtgggcgg taaaaaagga ttttctcatc aacattgaat taaaaaacag
     9481 cgtgatccgc tatgagggaa tggaagaaaa agtgctggag gcagtgaagc gattcaatgt
     9541 agaggagaga gtcatcctat ccacctttaa tcatgacagc ttggcgctat gcgcccggct
     9601 tgcgccgcat atcgaacggg cagtattaac ttcagatgtg ctttaccagg cagatcgata
     9661 tatcgcgtct attccggctt ccggctatca cccgaagtta aacagcccag gggtcacaga
     9721 tgaagtgcta aagaaaatga ggaacagttc gattaaggta aggccgtata cagtcaatcg
     9781 tccggaagat atgaagcgtc tcattgaagc gggagcagac ggcatgttta ccgactttcc
     9841 agaaaaggct tcggcattgc tgaaaaatga atagttgtta gaaggaggct gtttgacgca
     9901 gccttctttt ttcattcatt catgcccgtt tcaaagcata cattcataga agacaactag
     9961 aaattgtaag cactgtctat cttctgaatg aggtgaaacc atgaggaaaa cagtcattgt
    10021 aagtgctgca agaactccat ttggcaaatt cggcggagtt ttgaaagagg tgaaagctgc
    10081 tgagcttggg ggcattgtga tgaaggaggc gctgcaacgg gctggagtct ctggagatga
    10141 tgtagaagga aacgtcatgg gcatggttgt ccaggccggc tcagggcaga taccttcccg
    10201 tcaagctgcc cgtctggcgg gaatgccttg gagtgtgccg tcagaaacac tgaataaagt
    10261 ctgtgcttcc ggccttcgcg ctgtcacttt atgtgatcaa atgattcggg cgcaggatgc
    10321 ggacatactt gttgcggggg gaatggaaag catgagcaat attccgtatg ccgttcccgc
    10381 cgggcgctgg ggagcacgga tgggggacgg cgagcttagg gacttaatgg tgtatgacgg
    10441 attaacgtgc gcatttgacg aggtgcacat ggctgttcac ggaaatacag ctgccatgga
    10501 atatgcaatc tcacgaagag agcaggacga atgggcgttg agaagtcatg caagggcagc
    10561 taaggccgcc gatgaaggga agtttcagga tgaaattgtt cccgtcaact ggatcggtcg
    10621 aaaaggaaaa ccaaacgttg ttgataaaga tgaagcgatt cgccgtgaca caagtctgga
    10681 tcagctcgcg aaacttgctc ctatttatgc aagtgacggt tctatcacag ccggcaatgc
    10741 tcctggggtc aatgacggag ccggcgcgtt cgtgctgatg tctgaggaaa aagctgctga
    10801 gcttggcaaa cggcctctgg ctacaattct tggtttttca actacgggaa tgccagcgca
    10861 cgagctggcg gcagcgccgg gatttgccat taacaagctc ctgaaaaaga acggtttaac
    10921 tgtccaagat attgacttgt ttgaagtaaa tgaagctttt gcttcagttg ttttgacatg
    10981 tgaaaaaatc gtaggtttcg atcttgaaaa agtaaatgta aatggcggtg cgatcgcgct
    11041 cggccatccg atcggcgcga gcggggcgag aattctcatg acgcttgttt atgaattaaa
    11101 gcggcgggga gggggtctgg gcgttgccgc tatttgcagc ggggcagcac agggagacgc
    11161 cgtcttagtg caggttcatt aaaacatgat gaaaaagggg atttgaatgg aaatcaaaca
    11221 aatcatggta gctggcgcag gtcagatggg gagcggaatt gctcaaacag ccgccggcgc
    11281 gggcttttat gtgcggatgt atgatgtgaa tccagaggcc gcggaggcag gattgaaacg
    11341 gctgaagaaa cagctggccc gtgatgctga gaaaggaaaa aggaccgaga cggaagtgaa
    11401 gagcgtaatc agccgcattt cgatttctca aacgcttgag gaggcagagc atgcggacat
    11461 tgtgattgag gctatcgcag aaaacatggc ggcaaaaact gagatgttta aaacacttga
    11521 tcgcatttgc ccgcctcata cgattttggc cagcaataca tcttccttgc ctattacaga
    11581 aatcgctgct gtaacaaacc ggcctcaacg ggttattggc atgcatttta tgaatcccgt
    11641 ccctgtaatg aagctggtag aagtgattcg aggcttggct acatcagaag aaacggcctt
    11701 agatgttatg gcattagcgg aaaagatggg gaaaacagcg gtagaagtca atgattttcc
    11761 tgggtttgtt tccaaccgtg tgcttcttcc aatgattaat gaagccatct attgcgtgta
    11821 tgagggagtg gcgaagccgg aggcaataga tgaagtgatg aagctgggca tgaatcatcc
    11881 gatgggtccg tttgcattag cggattttat cggactggat acgtgtttat caattatgga
    11941 agttcttcac tcaggccttg gcgattccaa ataccgtcct tgcccgctgc tccgcaagta
    12001 tgtcaaagca ggctggcttg gcaaaaagag cggacgcggt ttttatgact atgaggagaa
    12061 gacttcctga agtctattcc atccgggggt ggccgagttg catgtaaccc aagagcaaat
    12121 catgatgcga aaaatggtgc gtgattttgc acgaaaagaa attgctcccg ctgcggaaat
    12181 catggagaaa acggacgaat ttccctttca gctgatcaaa aaaatgggtg aacacggcct
    12241 gatgggaata ccggtgccgg aacaatacgg cggtgctggg gcggacgttg tttcttatat
    12301 tttggcgatt catgagattt ctagaatcag tgcggctgtc ggcgtaattc tctccgttca
    12361 tacctcagtc ggcacgaatc cgattctgta tttcggcaac gaagaacaga agatgaaata
    12421 tataccaaat ctcgcgtcag gagaccattt gggcgcattt gcactaacgg agcctcactc
    12481 ggggtcggat gccgggagcc tccgcacaac agcaatcaaa aagaacggca aatacctatt
    12541 aaacggatcg aaaatattca taacgaatgg cggagcagct gatatctata tcacatttgc
    12601 tttaacagct ccagatcaag gcaggcacgg gatttcggct tttattgttg aaaaaaacac
    12661 acccggtttt accgttggaa aaaaagaaag aaagctgggg ctttatggct ccaatactac
    12721 ggaactgatt tttgataatg cagaagtgcc tgaagccaat ttgcttggca aagaggggga
    12781 tggctttcac attgccatgg cgaatttaaa tgtcggccgg atcggcattg cggcacaggc
    12841 cctcggaatt gcagaggcgg ctcttgagca tgccgttgat tatgcgaagc agcgagtgca
    12901 atttggaagg ccgattgcag ccaatcaagg catatcattt aagctggctg atatggcgac
    12961 tagagctgag gcggcaagac atcttgtcta ccacgctgca gaccttcata accgcggcct
    13021 aaactgtgga aaagaagcgt ctatggctaa acaatttgct tccgatgcag ccgtaaaggc
    13081 ggcgttagac gccgttcaaa tttatggggg atatggctat atgaaggatt atccagttga
    13141 gcgcctgctt cgcgatgcaa aggtgacgca aatttatgaa gggacgaacg agattcaaag
    13201 actgattatt tccaagtatt tgcttggcgg aacctgatag acaaaaaacg caaaaacgga
    13261 ggttgaggat atggaggaga aacagcatta ttctccaggg ttggacggtg tgattgcggc
    13321 agaaactcat atttcttatc ttgacaccca gtccagccag attttgataa gaggctatga
    13381 tttaatagaa ctttctgaaa caaaaagcta tctggagctt gtccatttat tgctggaggg
    13441 caggatgcca gaagaaagtg aaatggagac gctggaacgt aaaataaaca gtgcctcaag
    13501 cctgcctgct gatcatctcc gtctgcttga gctgctccct gaggacactc atccaatgga
    13561 tggtctgcgt accgacctgt cggcacttgc tggctatgat cggcaaattg atgatcggtc
    13621 tccttccgca aacaaagaac gcgcctatca gcttcttggg aaaatgcctg ccctcactgc
    13681 tgccagctac aggatcatta ataagaaaga accgattctt ccgcttcaaa ccctatccta
    13741 cagtgcgaat tttctctaca tgatgacagg gaaattgccg tcttcattgg aagaacagat
    13801 ttttgaccgg tcgctcgtcc tgtacagtga gcatgagatg ccgaattcaa cctttgcggc
    13861 cagggtcatt gcatctacac attcagatct ttatggggct ttgactgggg ctgtcgcttc
    13921 cctgaaaggg aatcttcacg gaggagcaaa cgaagctgtg atgtatttgc ttttggaggc
    13981 aaaaacgaca tctgattttg agcagctttt gcaaacaaaa ctgaaaagaa aagaaaaaat
    14041 catgggcttc ggccaccggg tgtatatgaa aaaaatggac ccgagagcac tcatgatgaa
    14101 agaggcgctg cagcaattat gcgataaagc cggtgaccat cgtttatatg agatgtgcga
    14161 agcgggtgag cggctgatgg agaaggaaaa agggctttac ccgaatttgg attactatgc
    14221 tgccccggtg tattggatgc tcggcatacc gattccttta tatacgccgg tctttttcag
    14281 cgcgagaacg tccggtttat gcgcccatgt gatcgaacag catgccaata atcggctctt
    14341 ccgtccccgt gtcagttaca tgggcccgcg atatcaaaca aaatcatgaa aggagctggt
    14401 agaatgccga aaacggatcg tgtaatcgta gaaatcacag actatgtgct tgaaaaagag
    14461 attactagtg ccgaagcgta tacaacagcg gggcatgtat tgctggatac cctgggctgc
    14521 gggatcttgg cgctacggta tccggaatgc gcaaagctgc ttggcccgat tgttccagga
    14581 acgactgtgc cgaatggaag caaagtgccg ggaacgtcat atgttctcga tcctgtgagg
    14641 gcagcgttta atatcggctg catgattcgc tggctcgatt acaacgatac gtggctggcg
    14701 gcggagtggg ggcatccatc cgataacttg ggaggaatcc ttgccgctgc tgattatgta
    14761 tcaagagtga ggctgtctga aggaaaagag ccgttaacgg tacgcgacgt acttgagatg
    14821 atgatcaaag cacacgagat ccaaggtgtg ctggcgttag aaaacagctt aaatcgagtt
    14881 ggccttgacc atgtgctgtt tgtcaaagtt gcgacaactg ctgttgcggc aaagcttttg
    14941 ggcggcggaa gagaagaaat caaaaatgcg ctttcgaatg catggattga caatgcagca
    15001 ttgaggacat accgccattc accgaataca ggctcgcgta aatcatgggc ggcaggagat
    15061 gcaacgagca gaggtgttca tttggcgctg atgtcgttaa aaggggaaat gggttatccg
    15121 acagccctga gtgcacctgg ttgggggttc caagacgttt tattcaataa gaaagagatc
    15181 aagcttgccc gtccgctcga cgcttatgtc atggaaaatg tgttatttaa agtgtcttat
    15241 cctgcggaat ttcacgccca gacagcggcg gagtgcgccg tcattcttca cccgcaggta
    15301 aagaaccgga ttgacgagat agaccgagtt gtcatcagaa cgcatgaatc cgctatccgt
    15361 atcattgata aaaaaggccc gctccacaat ccggcagacc gcgatcactg tctccaatac
    15421 attacagcaa tcggtttgct ttttggtgat atcaccgcac agcattatga agctgaaaca
    15481 gcgagtgatc cgagaataga taaacttcgt gataaaatgg aagtgactga aaataaaaca
    15541 tataccgagg attatttaaa acctgataaa cgttccatct caaatgccgt tcaggttcat
    15601 tttaaagacg gaacgagcac ggaaatggtg gaatgtgagt ttcccctcgg ccatcgtttt
    15661 cgaagagagg aagcagtgcc gaaactgctg gaaaagtttt ctgacaatct caaaacccat
    15721 tttcctgtta aacagcacaa acacatttat gagcgctgta ccagctatga gacattacaa
    15781 acgatgcgcg taaatgaatt cgtagacatg ttctgcatgt aaaaggggga ttttgtttca
    15841 tgtcgtggat cgtcaataag caatcgtcac aagaggagct tgccgggcgt ttccgcaagc
    15901 tgatgtcagc accggacatt cttcaaattc ccggcgccca tgacgggatg gccgctttgc
    15961 ttgcgaaaga agccggtttt tctgctattt atttgtccgg tgctgcctat acagccagca
    16021 gggggctgcc tgatttaggg atcatcacat cggcagagat agctgaacgg gccaaagatc
    16081 ttgtgcgtgc agctgatctg cctttgcttg tggatatcga tacgggattt ggcggtgtct
    16141 taaatgccgc ccgaacagcc cgggagatgc ttgaagccag ggtagcagcc gttcaaatag
    16201 aagaccagca gctcccaaaa aaatgcggac atttaaatgg caaacagcta gttccgataa
    16261 aggaaatgtc gcaaaaaata aaagccatta aacaagcggc accctccctt attgttgttg
    16321 cccgtactga tgccagggcg caggaagggc ttgatgccgc aataaaacgt tcagaggttt
    16381 acattgaggc gggagcggac gcaattttcc cggaagcgct acaggcggag aatgaattcc
    16441 gccagtttgc tgagcgtatc tccgttccgc tccttgcgaa tatgactgaa tttgggaaaa
    16501 cgccgtatta tcgtgccgat gaattcgaag atatggggtt tcacatggtg atatatcctg
    16561 tcacctcgct tcgatcggcg gcaaaagctt gtgagcggat gtttggtttg atgaaggagc
    16621 acggctcaca aaaagaagga cttcatgata tgcagacacg aaaagaactg tacgatacga
    16681 tttcttatta tgattatgaa gcgttagaca aaacgattgc caagaccgtt ttgcctgacg
    16741 aatagtgcaa caaaaaaagc cggagcatcc tccggctttt ttgcagctat cgttttctga
    16801 atcgcgggct gacttgattg cgttttctgt ctctgtataa aatgaacccg gccagcacat
    16861 agaggccgat cgcaaaaaag atgaatcctg acaacccttg gagccaaaga gctgaaaatg
    16921 gcttgattgt atggccgaaa agtgtatctc tcatcagttt aatgcctaaa gcagaaatag
    16981 ccccgggggt gactaatatt aaaagcgcaa gaagtcggct catcttcaga aaaccccttt
    17041 atcttttcat ttcctttatt gtccagcgga aaaaatattt tgtcaagaga agaaaacgtg
    17101 gtaacatagg gttgtgcaaa ttattgcaac ggaataaata ggtgtgcaaa ttttttcata
    17161 caaaggggta tcgggatgca aaaggtactg atagtaggtg ccggcaaaag gggaacggcg
    17221 ttattacata ttctgattaa aacagccatc atagatatca ttgccgtagt tgacaaagac
    17281 cccgaggcgc cgggattgaa agaagcagaa cagtatggga ttgccgtatc atctgattgg
    17341 aaaccttaca tacaacaaaa accggatatc gtcattcata ccaccggcga tcaagccgtg
    17401 tttgacgagc tccttcaaag aaagcatgaa gataccattg tcatgccggg aaaaatggca
    17461 tacatcgttt ttcagctgat ggaagaaaag cagcacctga ttcaaatgct aaaagagcaa
    17521 acctataaat atgacagaat ttttaattcc acccatgatg gaatgatttt tattgatatc
    17581 aatgaagaaa tcattctctt taaccatatg gccgaaaaaa tggtcgaaaa aaaacgtgag
    17641 gaagtcattg ggcgcccaat aaaagaagtg attccgagca cgaagttgcc gcggatttta
    17701 aaaacaagag tgcctgaata caaccagaag caactgttag gcgatcattt gcaaattgtg
    17761 accacaaggc tgccgattat tgatgaaggc ggacgtctgc tcggggctct ttgtgtgttt
    17821 aaagatatca ctgatgcggt cgagctggca gaggaagtga ccaacttaaa gcaggtccgt
    17881 acgatgctgg aggcgattat tcaatcctcc gatgaggcga tttctgtcgt tgatgaaaac
    17941 ggcatcggcc tgctaatcaa taaagcatat acgaaaatga cggggctttc tgaaaaagaa
    18001 gtcatcggca agcctgcaaa cactgatatt tccgaaggcg aaagcatgca tttaaaggtg
    18061 cttgaaacaa gacgtcctgt ccgcggtgtc agaatgaagg tcggcccgaa tgaaaaagag
    18121 gtcatcgtta atgtagcacc ggtgattgtg gacgggattt tgaaaggcag cgtcggcgtg
    18181 attcacgatg tttccgaaat taaaatgctg acagcggagc ttaaccgcgc cagacaaatt
    18241 attcgcacgc ttgaagcgaa atacacgttt gacgacatta tcggcaaaag cgagcaaatg
    18301 ctggttgcgc ttgagcaggc gaagctcggt gcgaaaacac ctgcaaccat cttgctgcgc
    18361 ggggaatcag gaacaggaaa agaactgttc gcccatgcca tccataacga aagtgaccgg
    18421 aaatacaata aatttattcg cgtgaattgt gcagcccttt ctgaaaacct gctcgaatca
    18481 gaattgttcg gctatgagga tggtgcgttt tcaggagcga agcgcggcgg taaaaagggt
    18541 ttatttgagg aagcaaataa cggcagtatt ttcttagatg aaatcggtga gctgacacaa
    18601 aatatgcagg ccaaattgct gcgcgtcctt caggaaaaag aaatcgtcag agtgggcggc
    18661 acgaaagcga tccctgtcaa cgtcagagtg atcgcggcga caaatgtaaa tattgaaaag
    18721 gcgatggcgg acggaacatt ccgggaagac ctgtattacc ggatcaaccg ctatccgatc
    18781 tccatcccgc ctttgcgtca gcggttggag gacattgaag cactgagcgt cagacttatc
    18841 caaaagatca accgggatta cggcaggaat gtaaaagggc tctcacagca agccttgcgc
    18901 gccttatctg cctaccattg gcctgggaat gtccgggagc ttgaaaatgt ccttggacga
    18961 gccatgattt ttctgaatcc gcatatggaa tggattgaaa aagatcactt gcctgtattc
    19021 gaacttgagc aaaaagaaaa tgacacagat cagggaacag gttttaatat tccggatatt
    19081 gaaggcgaaa agctgtctgt cgcagtagag aaatttgaag cgcatttgat ccagcaaacg
    19141 cttgaaaagc atcattttaa ccggacaaaa acagcaaaag ctctcggtgt cagcattcgg
    19201 aacttatatt acaaaatgga taaatatggc cttgcaaatg aaggcatgca ataatttgca
    19261 gaataaacgc aaacatctgc acgaatgttt caatatatct ggtatgacag cacccttaag
    19321 agctggcacg gaacttgcat aataaaaagc ggagtcgaaa caagaaaggt ggtagcagat
    19381 gaagctgaaa gatttaatcg gcaaagcgtc gatgcacaaa aataagacca ttgcggttgc
    19441 tcatgctgag gatgaggaag tgatccgggc tgtaaagctg gctgccgagc acctatccgc
    19501 ccgtttcttg ttaacgggcg acagcaaaaa actgaacgag ctgacatcat ccatgcaagg
    19561 gcatcaagtg gaaatcgtcc atgccgatac tcctgaggaa tcggcaaaat tagcggttcg
    19621 tgctgtgcat cataaaacag cggacgtttt aatgaaaggc aatgtgccga cttctgtttt
    19681 gcttaaagcg gtattgaaca gacaggaggg gcttcggtca tcaagtgtcc tttcccacgt
    19741 ggctgtcttt gatataccgg attttgaccg gctgatgttt gtgacagatt cggcaatgaa
    19801 tattgctcct tcgctggaag agcttcggca gattttgcaa aatgccgttc atgtggccca
    19861 tgcagtgggg aacaatatgc caaaagcagc tgctctggca gcggtcgaaa cggtgaaccc
    19921 taaaatggaa gcgaccgtga atgcagctgc tctagctcaa atgtacaaaa ggggccagat
    19981 caaaggctgc attgttgatg gaccacttgc tttggataac gcagtttcac aaattgccgc
    20041 ggcccagaaa aaaatttcgg gagacgtagc gggcaacgca gatatccttc tcgtcccaac
    20101 aattgaggcc ggcaatattt tatataaatc tctgatttat tttgccaagg ccagcgtggc
    20161 ggctgtcatt acaggagcca aagcaccgat tgccttaaca agcagagcgg actctgctga
    20221 aaataaactg tattccattg cgctggcaat atgcgcatct gaagaataca cacattagga
    20281 ggaacgaaca tggaactttt taaatatatg gagaaatacg attacgaaca attggtattc
    20341 tgccaggatg aacaatctgg cttaaaagcg attatcgcga ttcatgatac aacgcttggt
    20401 ccggcgcttg gcggaacgag aatgtggaca tatgaaaatg aagaagcggc tattgaagat
    20461 gcgctcagat tggctagagg catgacctat aagaacgcgg cggcaggctt aaaccttggc
    20521 ggcggaaaaa cagtcattat cggcgatccg cgcaaagaca aaaatgagga aatgttccgc
    20581 gcgtttggcc gctatattca agggctgaac ggcagataca tcacggctga agatgtgggc
    20641 acaacggtcg aggacatgga tatcattcat gatgaaacag actacgttac agggatttct
    20701 cctgctttcg gttcttctgg aaatccttct ccagtcacgg cgtacggggt gtatagagga
    20761 atgaaggcag cagctaaagc tgctttcgga accgactctc ttgaaggaaa aaacattgct
    20821 gtacagggtg ttgggaacgt agcctataac ctttgccgcc acttgcatga agaaggagca
    20881 aacttaatcg ttacagatat caacaaacaa tctgtacagc gtgcagttga agattttggc
    20941 gcccgtgcgg tagatcctga tgatatttat tcacaagact gcgatattta tgcgccgtgt
    21001 gcccttggtg cgactattaa cgacgacacc attaaacagc tgaaggcgaa agtgatcgca
    21061 ggtgcggcta acaaccaatt aaaagagaca cgccatggtg atcaaattca cgaaatgggc
    21121 atcgtttatg caccggatta cgtgattaac gcgggcggtg tcatcaacgt ggcagatgag
    21181 ctttacggct ataatgcaga acgtgcattg aaaaaagttg aaggcattta cggcaatatc
    21241 gagcgtgtac ttgagatttc tcagcgtgac ggcattcctg catatttagc ggctgaccgc
    21301 ttagcagagg aacggattga acgcatgcgc cgctcaagaa gccagttttt gcaaaacggc
    21361 cacagtgtat taagcagacg ttaagaaatt gatctggagg ttatgaaagt gctacatgac
    21421 gaaaaacgca ttctcacaat taatccaggc tcaacttcaa cgaaaatcgg tgtttttcat
    21481 aacgaaagaa gcatttttga aaaaacattg agacacaaca tagaagagct gcagcgattt
    21541 gaccgaatta ttgatcagta tgaatttcgt aaaaaccata ttctcgaaac gcttcatgag
    21601 cagggaatca atatttcaaa gtttgatgca gtctgcgcaa gaggcggcct tctccggccg
    21661 attgaaggcg ggacctacgt agtgaatgat gaaatgattg aggatttgaa aagcggctac
    21721 gccggtcagc atgcttctaa tctcggcggc attatcgcgc gggaaatcgc tgatggcctg
    21781 aatatccctt cgtatatcgt cgaccctgtt gtcgtagacg aaatgtcagt gcttgcgaaa
    21841 gtgtcaggca tgcctgaaat tgaacggaaa agcattttcc atgcgttaaa ccaaaaagct
    21901 gtcgctcgta aagcggcagc ctctcttggc aaacgatatg agaacatgaa aatgattatt
    21961 acccatatgg gcggaggtat tacaattggc gtccatgacc gcgggcgagt ggtagatgtc
    22021 aataacggcc tgcacggcga gggaccattc agtcctgaac gagcaggaac agtgcctgcg
    22081 ggagatcttg ttgatctatg tttttcaggg gaatatacaa aagaagaaat catgaaaaag
    22141 cttgttggca ccggcggact tttaggctat ctcggtacta atgatgcagt aaaagtggaa
    22201 cagatgattc aagggggcga tgaaaaagcc cgcttcattt atgatgccat ggcatatcag
    22261 gtagcaaagg aaatcggggc agccagcgcg gcgttaaaag gcgaagttga agcgattgtg
    22321 ctgacgggag gccttgcgta cggcaaaagc tttgtttctg ctatcagatc atacatagat
    22381 tggatttcag acgttttagt ctatccgggt gaaaatgaac tgcagtctct tgcccaaggg
    22441 gcgctcagag tattgcaggg cgaagagcaa tccaaacaat atcgtattga atagacagac
    22501 aggagtgagt caccatggca actgagtatg acgtagtcat tctgggcggc ggtaccggcg
    22561 gttatgttgc ggccatcaga gccgctcagc tcggcttaaa aacagccgtt gtggaaaagg
    22621 aaaaactcgg aggaacatgt ctgcataaag gctgtatccc gagtaaagcg ctgcttagaa
    22681 gcgcagaggt ataccggaca gctcgtgaag ccgatcaatt cggggtggaa acggctggcg
    22741 tgtccctcaa ctttgaaaaa gtgcagcagc gtaagcaagc cgttgttgat aagcttgcag
    22801 cgggtgtaaa tcatttaatg aaaaaaggaa aaattgacgt gtacaccgga tatggacgta
    22861 ttcttggacc gtcaatcttc tctccgctgc cgggaacaat ttctgttgag cggggaaatg
    22921 gcgaagaaaa tgacatgctg atcccgaaac aagtgatcat tgcaacagga tcaagaccga
    22981 gaatgcttcc gggtcttgaa gcggacggta agtctgtact gacttcagat gaggcgctcc
    23041 aaatggagga gctgccacaa tcaatcatca ttgtcggcgg aggagttatc ggtatcgaat
    23101 gggcgtctat gcttcatgat tttggtgtga aggtaacggt tattgaatac gcggatcgca
    23161 tattgccgac tgaagatcta gagatttcaa aagaaatgga aagtcttctt aagaaaaaag
    23221 gcatccagtt cataaca
//
