LOCUS       c00093_gnlPro..        12562 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CKHDMJND_137.
ACCESSION   c00093_gnlPro..
VERSION     c00093_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 05:33:47
            Original ID  :: gnl|Prokka|CKHDMJND_137
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 91951
            Orig. end    :: 104513
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12562
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[101951:104476]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12525
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..12562
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12562
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             159..935
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ECH_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg93_92"
                     /sec_met_domain="ECH_1 (E-value: 6.1e-66, bitscore: 214.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAISLAVDQFVAVLTIHNPPANALSSRILEELSSCLDQCETDAG
                     VRSIIIHGEGRFFSAGADIKEFTSLKGNEDSSLLAERGQQLMERIESFPKPIIAAIHGA
                     ALGGGLELAMACHIRIATEDAKLGLPELNLGIIPGFAGTQRLPRYVGTAKALELIGSGE
                     PISGKEALDLGLVSIGAKDEEEVLEKAKALAAKFAEKSPQTLASLLELLYSNKVYSYEG
                     SLKLEAKRFGEAIESEDAKEGIQAFLEKRKPQFKGE"
     CDS             950..1723
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 159.7;
                     E-value: 2.4e-49)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg93_93"
                     /sec_met_domain="ETF (E-value: 3.9e-49, bitscore: 159.7,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLFVLMKRTFDTEEKIVIETGKIQDDGAEWIINPYDEYAIEEAI
                     QLKEKHGGTITAVTVGGEEAEKELRTALAMGCDQAVLINIEDDLEEPDQYSISQVLYHY
                     MKDQEFDLILGGNVAIDGGSGQVAPRLAELLDIPCITTITKLEINGTDAEAERDVEGDV
                     EKMKTTLPLLVTAQQGLNEPRYPSLPGIMKAKKKPLEELELDDLDLDEEDAEPKLKTIE
                     RFLPPKKEAGKLLQGEPDEQAKELVSLLRSEAKVI"
     CDS             1759..2736
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 152;
                     E-value: 5.6e-47)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg93_94"
                     /sec_met_domain="ETF (E-value: 9.2e-47, bitscore: 152.0,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 1.1e-37, bitscore:
                     120.8, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKKVIVLGEIRDGELRNVTFEAIAAGRTISGDGEVIGVLIGENV
                     QSIAQELIHYGADKVLTAEDPRLKTYTADGYSQVMRGVIEQENPDSVIFGHTAMGKDLS
                     PKLAARLQTGLISDAIDVSVTGGNVVFTRPIYSGKAFERVISTDPMIFATIRPNNIQAS
                     EKDTSRSGSIESMNVSLTDLRTVIQEVVKKTADGVDLSEAKIIVAGGRGVKSKEGFQPL
                     QALAEVLGAAVGASRGACDADYCDYALQIGQTGKVVTPDLYIACGISGAIQHLAGMSNS
                     KVIVAINKDPEADIFKIADYGIVGDLFEVVPLLTEEFKQLNIHS"
     CDS             2933..4441
                     /locus_tag="ctg93_95"
                     /transl_table=11
                     /translation="MKGMIRGMSEHQAVIQTDIVKGTINKNIYGHFAEHLGRGIYEGIW
                     VGTDSDIPNINGIRKDVLEALKQLHIPVLRWPGGCFADEYHWANGVGDRKTMLNTHWGG
                     TIESNEFGTHEFMMLCELLECEPYICGNVGSGTVQEMAEWIEYMTFEEGTPMSDWRKQN
                     GREEPWNLKYFGVGNENWGCGGNMHPEYYADLYRRFQTYVRNYSGNDIYKIAGGANVDD
                     FNWTDVLMKKAAGLMDGLSLHYYTIPGDFWKGKGSATEFTEDEWFITMKKAKYIDELIQ
                     KHGTIMDRYDPEQRVGLIIDEWGTWFDPEPGTNPGFLYQQNTIRDALVAASHFHIFHQH
                     CRRVQMANIAQTVNVLQAMILTGGERMLLTPTYHVFNMFKVHQDASHLATETMSADYEW
                     NGETLPQISISASKQAEGDINITICNIDHQNKAEAEIELRGLHKAADHSGVILTAEKMN
                     AHNTFDDPHHVKPESFRQYTLSKNKLKVKLPPMSVVLLTLRADS"
     CDS             4765..5079
                     /locus_tag="ctg93_96"
                     /transl_table=11
                     /translation="MAIVKATDQSFSAETSEGVVLADFWAPWCGPCKMIAPVLEELDQE
                     MGDKLKIVKIDVDENQETAGKYGVMSIPTLLVLKDGEVVETSVGFKPKEALQELVNKHL
                     "
     CDS             5215..6987
                     /locus_tag="ctg93_97"
                     /transl_table=11
                     /translation="MNKQLKEKLALLPDQPGCYLMKDRQQTVIYVGKAKVLKNRVRSYF
                     TGSHDAKTQRLVTEIEDFEYIVTSSNLEALILEMNLIKKHDPKYNVMLKDDKTYPFIKL
                     THERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCLYYH
                     LGQCLAPCVKDISEETNRELVESITRFLRGGYNEVKKELEEKMNEAAENLEFERAKELR
                     DQMAHIESTMEKQKMTMNDLVDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPLYQ
                     EADEEFLTFIGQFYSKNNHFLPKEILVPDSVDQSMIEQLLETNVHQPKKGPKKELLMLA
                     HKNAKIALKEKFSLIERDEERSIGAVQKLGEALNIYTPHRIEAFDNSNIQGTNPVSAMI
                     VFIDGKPYKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQ
                     INAARDVIENELGLDIPIAGLAKDEKHRTSNLLIGDPLEVVYLERNSQEFYLLQRIQDE
                     VHRFAISFHRQIRGKSAFQSVLDDIPGIGEKRKKMLLKHFGSVKKMKEASLEDIKKAGV
                     PTAAAQLLYDKLQK"
     CDS             7356..8582
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg93_98"
                     /sec_met_domain="AA_kinase (E-value: 5.5e-56, bitscore:
                     182.5, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLIVQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMGK
                     STDELVSLAKAISDQPSKREMDMLLATGEQVTISLLSMALEEKGYDAVSYTGWQAGIRT
                     EAIHGNARITDIDTSVLADQLEKGKIVIVAGFQGMTEDCEITTLGRGGSDTTAVALAAA
                     LKADKCDIYTDVPGVFTTDPRYVKSARKLEGISYDEMLELANLGAGVLHPRAVEFAKNY
                     QVPLEVRSSTETEAGTLIEEESSMEQNLIVRGIAFEDQITRVTIYGLTSGLTTLSTIFT
                     TLAKRNINVDIIIQTQAEDKTGISFSVKTEDADQTVAVLEEYKDALEFEKIETESKLAK
                     VSIVGSGMVSNPGVAAEMFAVLAQKNILIKMVSTSEIKVSTVVSENDMVKAVESLHDAF
                     ELSKHPSAV"
     CDS             complement(8626..9072)
                     /locus_tag="ctg93_99"
                     /transl_table=11
                     /translation="MKSKFEASIDNLKEIEMNAYAYELIREIVLPDMLGQDYSSMMYWA
                     GKHLARKFPLESWEEFPAFFEEAGWGTLTNVSAKKQELEFELEGPIISNRLKHQKEPCF
                     QLEAGFIAEQIQLMNDQIAESYEQVKKRADKVVLTVKWDMKDPV"
     CDS             9365..9976
                     /locus_tag="ctg93_100"
                     /transl_table=11
                     /translation="MSGNREFYFRRLHSLLGVIPVGIFLIQHLVVNQFAARGAEAFNSA
                     AHFMDSLPFRYALEIFIIFLPLIYHAVYGVYIAFTAKNNAGQYSYMRNWLFVLQRVTGI
                     ITLIFVSWHVWETRIAAQMGAEVNFDMMANILSSPAMLGFYIVGVLSTIFHFSNGLWSF
                     AVTWGITVTPRSQRISTYVTLIIFVALSYVGLKAIFAFVY"
     CDS             10001..11761
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 296; E-value:
                     1.7e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg93_101"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.8e-90, bitscore:
                     296.0, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 8e-43, bitscore:
                     138.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSSIIVVGGGLAGLMATIKAAESGMAVKLFSIVPVKRSHSVCA
                     QGGINGAVNTKGEGDSPWEHFDDTVYGGDFLANQPPVKAMCEAAPSIIHLLDRMGVMFN
                     RTPEGLLDFRRFGGTQHHRTAYAGATTGQQLLYALDEQVRRYEVAGLVTKYEGWEFLGA
                     VLDDDRTCRGIVAQNLTNMQIESFRSDAVIMATGGPGIIFGKSTNSMINTGSAASIVYQ
                     QGAYYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRVWTYKDGKPWYFLEEKYPAYGN
                     LVPRDIATREIFDVCVNQKLGINGENMVYLDLSHKDPKELDIKLGGIIEIYEKFMGDDP
                     RKLPMKIFPAVHYSMGGLWVDYDQMTNIPGLFAAGECDYSMHGGNRLGANSLLSAIYGG
                     MVAGPNAVKYVNGLESSAEDMSSSLFDAHVKKEEEKWADIMSMDGTENAYVLHKELGEW
                     MTANVTVVRHNDKLLKTDDKIQELMERFKKININDTTKWSNQGAMFTRQFSNMLQLARV
                     ITLGAYNRNESRGAHYKPDYPERNDDEWLKTTMAKHVSPYEAPEFEYQDVDVSLITPRK
                     RDYSKKKVAK"
     CDS             11764..12525
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 96.2; E-value: 3.7e-30)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg93_102"
                     /sec_met_domain="Fer2_3 (E-value: 6e-30, bitscore: 96.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.1e-11, bitscore: 36.9,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0004, bitscore: 13.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIRR
                     NPVNVKGEKTTPVTWDMNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRLKPMKTFP
                     VVRDLQVDRSRMFDSLKKVKAWIPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVCLE
                     ACPNVNSKSKFMGPAPMSQVRLFNAHPTGAMNKSERLEALMDEGGLADCGNSQNCVQSC
                     PKGIPLTTSIAALNRDTNLQAFRNFFGSDRV"
ORIGIN
        1 gacgtccgcc tcgcccggca gatgattttt ggaacgattg acgaaaccgt gacaacttgg
       61 gtgatgaatg accaaaagta cgatctcgct gcgctttcaa acagcgtttt agaattattg
      121 gtgtccggaa ttcataataa gtaaaggagt tctgtcctat gaatgcaata tcactggcag
      181 ttgatcaatt tgtggcagtt ttgacgattc acaatccgcc ggcaaatgcg ctttccagcc
      241 ggatattaga agagctgtct tcctgtcttg atcaatgtga gacagatgca ggcgtacgaa
      301 gcattatcat tcacggcgag ggaagatttt tctcagccgg cgctgatatt aaagaattta
      361 catcgcttaa aggcaatgag gattcctcat tgctcgctga gcgcggccag cagttaatgg
      421 agagaatcga aagctttcca aaaccgatta tcgcagcgat tcacggcgct gctctcggag
      481 gcgggctgga gcttgcgatg gcctgtcata tcagaatcgc aacagaagat gctaagctgg
      541 ggctcccgga gcttaatctc ggtatcattc cgggttttgc ggggacacag cgccttccga
      601 gatatgtcgg cacagccaaa gcattagagc tcatcggatc aggagaacca atatccggaa
      661 aagaagcgct tgatctcgga cttgtctcaa ttggagcaaa agatgaggaa gaagtgcttg
      721 aaaaagcaaa agcacttgcc gctaagtttg cagagaagag cccgcaaacg ctggcatctt
      781 tgcttgaact tctttattcc aacaaggtgt attcctatga aggcagctta aagcttgaag
      841 caaagcgatt tggggaagca attgagtcag aggacgccaa ggaaggcatc caggcatttc
      901 tcgaaaaaag aaagcctcag ttcaaaggcg aataaaaggg gatatgatca tgaatctatt
      961 tgtactgatg aaacggacgt ttgacacaga agaaaaaatc gtcattgaaa caggaaagat
     1021 tcaggatgac ggagcggaat ggatcattaa tccatatgat gagtacgcga tagaagaagc
     1081 tatccagctg aaggaaaagc atggcggcac gatcaccgcc gtcacggtcg gcggtgaaga
     1141 agcggagaaa gaattgcgta cggcgcttgc catgggttgt gaccaagctg ttttaatcaa
     1201 catagaagat gatctcgaag aacccgacca atattccatt tctcaagttt tataccacta
     1261 tatgaaggat caggagtttg atttgattct cggcggaaat gttgccattg acggaggatc
     1321 aggacaagtg gcgcctcggc ttgccgagct actggacatt ccatgtatca ctacgatcac
     1381 caaactcgaa atcaacggca ctgatgcaga agcagaaagg gacgtcgaag gggatgttga
     1441 aaaaatgaaa acgacgctcc cattgcttgt cacagctcag cagggcttaa acgagccgcg
     1501 ctatccatcg cttccgggaa ttatgaaggc taagaaaaag ccgcttgaag agcttgaact
     1561 tgatgatctt gacctggacg aagaggatgc tgaaccaaag ctgaaaacca ttgagcgttt
     1621 tctgccgccg aaaaaagaag ccgggaagct tctccaaggt gagcctgacg aacaggcaaa
     1681 agagcttgtc tcattgctcc gcagcgaagc taaagtcatt taaagcttgg acattcaaag
     1741 aaacaggggg atgttagaat gggaaaaaaa gtgatcgtgc ttggagaaat acgcgatggg
     1801 gaattgcgga atgtcacctt tgaagcaata gctgcaggaa gaaccatttc aggagatgga
     1861 gaagtcatcg gtgttctcat cggtgaaaat gtacaaagca ttgcacaaga gcttattcat
     1921 tacggagcag ataaagttct taccgctgag gacccgaggc tgaaaacata cacggcagac
     1981 gggtacagcc aggtcatgag aggtgttatc gagcaagaaa atcctgattc agtcatcttc
     2041 gggcatacgg caatgggcaa ggatctttca ccgaagcttg ctgcccgtct gcaaacaggc
     2101 ttaatttctg atgctataga tgtaagcgtt accggaggga atgttgtgtt cacacgcccg
     2161 atttactcgg ggaaagcttt tgaacgcgtc atttcaaccg atccgatgat ctttgcaaca
     2221 attcgcccca ataacattca agcttcagaa aaagacacca gcagatcggg aagcatcgaa
     2281 agcatgaatg tctctcttac tgaccttcgc accgtgattc aagaggtcgt gaaaaaaacg
     2341 gcggacggtg ttgatctctc cgaagcgaaa attatcgttg cgggcggccg aggagtcaaa
     2401 agcaaggaag gatttcagcc gctgcaggcg cttgcagagg tgctaggggc cgcggtcggg
     2461 gcttctcgcg gggcatgtga cgctgattat tgcgattacg cgctccaaat cgggcagacc
     2521 gggaaagtcg ttactccgga tttgtacatt gcatgcggca tttccggcgc catccagcat
     2581 ttggccggca tgtcaaacag caaggtgatc gtcgccatca ataaagaccc cgaagccgat
     2641 atctttaaaa tagcggatta cggcatcgtc ggtgatttat ttgaagttgt cccgttatta
     2701 actgaggaat tcaaacaatt gaatatacac tcataaagga aatcccggac tttaaaagtt
     2761 cgggattttt tcatatttat aaatacatac gtacaaatat aaaaacaata gaaaatgtcg
     2821 ttgacatgta cgaacatata taatatggtt actttaaaag cgcttacatt catgctgact
     2881 cctcaggcaa aagacagatc acatatttga ctgtggtgct tttcatatcc gtatgaaagg
     2941 aatgatcaga ggcatgtctg aacatcaagc agtgattcaa acagatatcg taaaaggaac
     3001 cattaacaaa aatatatacg gtcattttgc tgagcattta ggaagaggga tttatgaggg
     3061 gatctgggtt ggaacggact cagacatccc caatatcaac gggatacgaa aggacgtgct
     3121 ggaggcgctc aaacagctgc acattcctgt cctcaggtgg ccgggcgggt gttttgcgga
     3181 cgaataccat tgggcaaacg gtgtcggtga ccgtaagaca atgctgaaca ctcactgggg
     3241 cggtacaatt gaatcaaatg aattcggaac gcatgaattt atgatgcttt gcgagctgct
     3301 tgaatgtgag ccatatattt gcggcaatgt cggaagcgga accgttcagg aaatggcgga
     3361 gtggattgag tatatgacat ttgaagaagg cacgccgatg tcagactgga gaaaacaaaa
     3421 tggaagagaa gagccttgga atctgaaata tttcggcgtg ggtaatgaaa attggggctg
     3481 cggcggcaac atgcatcccg aatactacgc agatctgtac cggcgttttc agacttatgt
     3541 ccgcaattac agcgggaatg acatttataa aattgcaggc ggagcaaatg tggatgattt
     3601 taattggacg gacgtgctta tgaaaaaagc cgctggcctg atggacgggt tgagtcttca
     3661 ttattacacg attccggggg atttctggaa gggcaaagga tcagccacag aattcacgga
     3721 agatgagtgg tttattacga tgaaaaaagc caaatacatc gatgaattga ttcaaaaaca
     3781 cggcacgatt atggaccggt acgatccgga gcagcgggtc gggctgatta ttgatgaatg
     3841 gggcacgtgg tttgatcccg agccaggcac gaatcccggt ttcttatatc agcaaaacac
     3901 cattcgtgat gcactggtgg cggcttctca tttccacatt ttccatcagc attgccgccg
     3961 ggtgcaaatg gccaacatcg cccaaacagt aaatgttctt caagcgatga ttttgactgg
     4021 gggagagcgg atgcttttga caccgacgta ccatgtattc aatatgttta aggtgcacca
     4081 ggacgcttct catttagcca cagagacaat gtctgccgac tatgaatgga acggtgaaac
     4141 gcttccgcaa atcagcattt cagcgtcgaa acaagctgaa ggcgatatca atatcacaat
     4201 ttgcaacatc gatcaccaaa acaaggcaga ggcggaaatc gagctgaggg gcctacacaa
     4261 ggcagcggac cattccggag tcattcttac ggcagaaaaa atgaatgcgc ataacacgtt
     4321 tgacgatcct catcatgtca aaccggaatc cttcagacaa tacacgctca gcaaaaacaa
     4381 actgaaagta aaactcccgc caatgtcagt cgtcttactt acgctgcgtg ctgattctta
     4441 atcgcgcaag agcgccggag cttcatgccg gcgctctttt tcaggtttta aaacagctcc
     4501 ggcagggcat ggtaaagtac atgacagtga agaggagatg tgatcttatg cttcgtacca
     4561 ttttaatgat tattggagca attgtagtga tcggggccat tatcagattt gtgttttaaa
     4621 aaaagagcat atcccattca accatataaa taatgagtaa accggctgtg atcaggaaaa
     4681 aataatttgt aagcattaaa atagcgtgaa cgaatgggag atgctatact aaaaatcatc
     4741 atttcacatt ggaggaattc aataatggct atcgtaaaag caactgatca atctttctca
     4801 gctgaaacaa gcgaaggcgt cgtactggca gacttctggg ctccttggtg cggaccttgt
     4861 aaaatgattg cacctgttct tgaagaattg gatcaagaaa tgggagacaa actgaaaatc
     4921 gtaaaaatcg atgtagacga aaaccaagaa actgccggaa aatacggcgt tatgagcatc
     4981 ccgactcttc ttgtgttaaa agacggcgaa gtagttgaaa cttcagtcgg cttcaaacca
     5041 aaagaagcgc ttcaagagct tgtaaacaaa catctttaat tttccgctgc ttacatgcca
     5101 gagcgattcc gattgaggga tcgctttttt tattcgccaa ttgtgaacca tagagaaaaa
     5161 caaacgttcg tgttaaactg gaaataaagg attaaacata aggaagggta acatatgaac
     5221 aaacaactga aagaaaaact cgccctcctt cctgatcaac cgggttgtta tctcatgaag
     5281 gaccggcagc agactgtgat ctacgtaggg aaagcaaaag tgctgaaaaa cagagtgcgc
     5341 tcctacttca ccggttctca cgacgcgaaa acccaaaggc ttgtgacgga aatcgaggat
     5401 tttgaatata tcgtgacgtc ctccaatctt gaagcgctta ttttagaaat gaatctgatc
     5461 aaaaagcatg atccgaaata caacgtcatg ctcaaagacg acaaaaccta tcctttcata
     5521 aaactcaccc atgaacgcca cccaaggctg attgtcacac gcaatgtcaa aaaagacaaa
     5581 gggcgctatt tcgggccgta tccgaatgta caggcagcaa gggaaacaaa aaaactgctc
     5641 gaccgtctgt atcctctcag aaaatgctcc aagctcccgg acagagtgtg cctttactat
     5701 catctgggcc aatgcctcgc tccgtgtgta aaggatattt ccgaagagac gaacagagag
     5761 ctggttgaaa gcattacacg tttcttaagg ggcggctata atgaggtcaa aaaagagctt
     5821 gaagagaaaa tgaatgaagc tgctgagaat cttgagtttg aacgagcaaa agagcttcgt
     5881 gaccaaatgg cccatattga atcaacgatg gaaaaacaaa aaatgacgat gaacgatcta
     5941 gtcgaccgtg atgtgttcgc gtacgcgtac gataagggct ggatgtgcgt gcaggtcttt
     6001 ttcatccgcc aaggaaagct cattgaacgc gatgtcagca tgttcccgct ttatcaggaa
     6061 gcagatgaag agttcctcac gttcatcggg cagttctatt caaaaaacaa ccacttcctt
     6121 ccgaaggaga ttttagttcc ggacagcgta gatcaatcca tgatcgagca gctgctggaa
     6181 acaaacgttc accagccgaa aaaaggcccg aaaaaagaac tgctcatgct tgcccataaa
     6241 aatgcgaaaa tcgcattgaa agaaaaattc tctttaatcg aacgggacga ggagcgttca
     6301 atcggggcag tgcagaaact aggtgaggca ttaaatattt atacgccgca cagaattgaa
     6361 gcgtttgata actcaaatat acaggggaca aacccggttt ccgcgatgat tgtgtttatc
     6421 gatggcaaac catacaaaaa ggaataccgc aaatataaaa tcaaaactgt tacagggccg
     6481 gatgattacg gttctatgag agaggttgtc agaagacgct atacgagagt gcttcgtgag
     6541 aatctgccgc tgcccgatct gatcatcatt gacggaggaa aagggcagat caacgcagca
     6601 agggatgtca ttgaaaatga actcggcttg gatatcccga tcgccggttt agcgaaagat
     6661 gaaaaacaca gaacctcaaa tttactgatc ggtgatccgc tggaggtggt gtatctggaa
     6721 cgaaacagcc aggaatttta cctcctgcag cgcattcagg acgaggtgca ccgttttgca
     6781 atcagttttc acaggcaaat ccgcggaaaa agcgcgtttc aatccgtttt ggacgacatc
     6841 ccgggtatcg gagagaaaag aaagaaaatg ctgttaaagc atttcggttc cgttaaaaaa
     6901 atgaaggaag caagccttga ggacatcaaa aaagccggtg ttcccacagc ggcggctcag
     6961 ctcctttacg acaaattgca aaaataatgt tgtcctttta aataagatct gataaaatgt
     7021 gaactaattt catagttaga tcgtgttata tggtgaagat agaggtgcga acttcaagag
     7081 tatgcctttg gagaaagatg gattctgtga aaaaggctga aaggggagcg tcgccgaagc
     7141 aaataaaacc ccatcggatt atttgctggc cgtgcattga ataaatgtaa ggctgtcaag
     7201 aaatcatttt cttggagggc tatctcgttg ttcataatca tttatgatga ttaattgata
     7261 agcaatgaga gtattcctct cattgctttt tttattgtgg acaaagcgct ctttctcctc
     7321 acccgcacga accaaaatgt aaagggtggt aatacatggg tcttattgta caaaaattcg
     7381 gaggcacttc cgtcggctca gtcgaaaaaa ttcaaaatgc ggcaaaccgc gcaattgcag
     7441 aaaaacagaa aggccatcaa gtcgttgtcg tcgtttcagc aatgggaaaa tccactgacg
     7501 aattggtcag ccttgcaaaa gctatttctg accagccgag caaacgcgaa atggatatgc
     7561 tgctggcgac aggcgagcag gtcacgattt cactcctttc aatggcattg gaggaaaaag
     7621 gctatgacgc tgtgtcttat actggctggc aggcgggaat ccgtacggag gccattcacg
     7681 gaaacgccag aattacagat atcgacactt cggttttagc agaccagctt gaaaaaggaa
     7741 aaattgtcat tgttgcagga ttccaaggca tgacagagga ttgtgaaatt acgacattgg
     7801 gccggggcgg ttcagataca acagcagttg ctttggctgc cgctttaaaa gctgataaat
     7861 gtgacatata cacagacgtg ccaggcgtgt ttacaaccga tccgcgctat gtgaaatcag
     7921 cgagaaaact tgagggcatc tcatacgatg aaatgcttga gcttgccaat ttaggcgccg
     7981 gtgttcttca tccgagagca gttgagttcg cgaaaaatta ccaagtgccg ttagaagtgc
     8041 gttcaagtac agaaaccgaa gcgggaacat taattgagga ggaatcatcc atggaacaga
     8101 atttaattgt cagaggcatt gcatttgaag atcaaatcac aagagtaacc atttacgggc
     8161 tgactagcgg cctgacaact ttgtctacta tttttacaac tcttgccaaa agaaacataa
     8221 acgtggatat cattatccaa acgcaggccg aggacaagac tggaatttcc ttctctgtca
     8281 aaacagaaga tgcagaccaa accgttgcgg tgcttgaaga gtataaagac gcgctggaat
     8341 ttgagaaaat cgagacagaa agcaaattgg ctaaagtatc tattgttgga tccggcatgg
     8401 tctcaaatcc cggtgtagcg gctgaaatgt ttgctgtact ggcgcaaaaa aacattttaa
     8461 tcaaaatggt cagcacatct gaaatcaaag tgtcaacagt cgtaagcgaa aatgacatgg
     8521 tgaaagcagt cgagtcgctt cacgatgcat ttgagctttc aaaacaccct tcagctgtgt
     8581 aatgacaatc aaaaaggcgg gactatgcag tcaccgcctt tttgattaca ctgggtcttt
     8641 catatcccat ttcacagtca gaaccacttt atcggctctc tttttcactt gttcatatga
     8701 ttcggcaatc tgatcattca tcaattgaat ttgttcagcg ataaaaccag cctccagctg
     8761 aaagcaaggt tctttctgat gtttaagccg gttggaaatg atcggccctt caagttcaaa
     8821 ttcaagctcc tgttttttag cgcttacgtt ggtgagggtt ccccagcccg cttcttcaaa
     8881 gaaggccgga aattcctccc atgattcaag aggaaactta cgggcgagat gttttcctgc
     8941 ccaatacatc atggaagagt aatcttggcc aagcatatct gggagaacga tctctcgtat
     9001 tagttcgtag gcataggcgt tcatttcaat ttcttttagg ttgtcaatag atgcttcaaa
     9061 tttagacttc atatctgtct cccctctctc ctgcgtatat tatagctcaa acagggggga
     9121 ggattacaga atgatcctgt aattcttatg aaaaattaag caagaaatat atattgataa
     9181 aataaaattt ttcaatcaac taatcaattc ggaaaattat aatttatgta cgcgttttct
     9241 tgacgccctt ttgagggagg agtaaaatga aattgtcaat aaatcttaat aaagtgctta
     9301 caattgaaag aagtggggga agagatttag cacatttcgc acttatcaaa cagggggtaa
     9361 agtaatgtct gggaacagag agttttattt tcgaagattg cattccttgc ttggcgtcat
     9421 accggtcggc atctttctta ttcagcattt agtcgtcaac cagtttgccg caaggggcgc
     9481 tgaagcattc aatagcgctg ctcattttat ggatagcctg cctttcaggt atgccttgga
     9541 aatttttatt atcttcttac cattaattta tcatgcagtt tatggtgtgt acatagcgtt
     9601 tactgcgaaa aataacgcag gccaatacag ctacatgaga aactggctat tcgtcctgca
     9661 gcgtgtaacc ggtatcatca ccctcatttt tgtcagctgg cacgtgtggg aaacccgcat
     9721 tgccgcacaa atgggcgctg aggtcaattt cgacatgatg gcgaatattt tgagctctcc
     9781 ggctatgctt ggtttttaca ttgtcggtgt tttatcaaca attttccact tctcgaacgg
     9841 tttatggtct ttcgctgtta cttggggcat cacggtaacg cctcgttctc aaagaatttc
     9901 gacatacgtt acgctgatta tttttgttgc actgtcatat gtaggcttaa aagcgatttt
     9961 tgcatttgtt tactagatta ctagagggag aggggctatc atgagtcaat caagcattat
    10021 cgtagtcggc gggggtcttg ccggtctcat ggcgacaatt aaagcagcgg aatcaggaat
    10081 ggcggttaag ttgttttcca tcgttcctgt caaacgttct cattcggttt gtgcgcaagg
    10141 cggcataaat ggagcggtca atacaaaagg ggaaggtgac tctccgtggg aacattttga
    10201 tgacacggta tacgggggag actttcttgc caaccagccg ccggtcaagg cgatgtgtga
    10261 agcggcgcct tcgatcatcc acttattaga ccggatgggc gtcatgttta accggacgcc
    10321 tgaaggcctg cttgatttcc gccgattcgg gggtacacag caccacagaa ctgcttatgc
    10381 tggtgcgacg acgggacagc agctgcttta cgcactggac gagcaagtgc gcagatacga
    10441 agttgcgggt ctggtcacaa aatacgaagg ctgggaattc cttggcgctg ttttagatga
    10501 tgacagaacc tgccgcggaa ttgttgcaca aaacctgaca aacatgcaaa ttgaatcctt
    10561 ccgttcagac gctgtcatta tggcgacggg cggaccggga atcatctttg gaaaatcaac
    10621 gaactccatg attaatacag gatctgctgc atcaatcgtt tatcagcagg gagcgtatta
    10681 tgcaaacgga gaattcattc aaatccaccc gacagccata ccgggcgatg acaaattaag
    10741 actgatgagt gaatcagcgc gtggtgaagg cggtcgcgtg tggacatata aagacggcaa
    10801 accatggtat ttcctggagg aaaaatatcc ggcatacgga aacctggtgc cgcgtgatat
    10861 tgcgacacgc gaaatatttg atgtgtgtgt gaaccagaag cttggcatta acggtgaaaa
    10921 catggtatat ctcgatctgt ctcataaaga tccgaaagag cttgatatta agcttggagg
    10981 catcattgag atttatgaga aattcatggg agacgacccg cgtaagctcc caatgaaaat
    11041 cttcccggcg gtccattatt ctatgggcgg tttatgggtg gattacgatc aaatgacaaa
    11101 tatccctgga ctgtttgcgg ctggggaatg tgattattct atgcacggtg gcaaccgctt
    11161 gggagcgaac tccctgctgt ctgcgattta cggaggcatg gtggccggtc cgaatgcggt
    11221 gaaatatgta aacggcttag aatcttcagc ggaagacatg tcttcatctt tattcgacgc
    11281 tcacgttaag aaagaagaag aaaaatgggc tgatattatg agtatggacg gaaccgaaaa
    11341 tgcctatgtt cttcacaaag agctcggtga gtggatgacg gcgaacgtaa cggttgtccg
    11401 ccataatgac aagcttttga aaacggatga caaaattcag gagttaatgg agcgcttcaa
    11461 aaagatcaac atcaatgaca cgacaaaatg gagcaaccag ggagcgatgt tcacacgcca
    11521 gttctcaaac atgcttcagc ttgctagggt gattaccctt ggcgcataca accgtaatga
    11581 aagccggggc gcccattata aaccggatta tcctgaacgt aatgatgatg aatggctcaa
    11641 aacaacaatg gctaaacatg taagcccgta tgaagcgccg gaatttgagt atcaggatgt
    11701 cgatgtatca ctgataacgc ctcggaaacg ggattactcg aagaagaagg tggcgaaata
    11761 atcatgagtg aacaaaaaac catacgattt attatcacac gtcaagatac agccgacagc
    11821 acgccttacg atgaagaatt tgagattcca taccgcccga atctgaacgt catttccgct
    11881 ctgatggaaa tccgccggaa tccggttaat gtcaaaggtg agaagacaac ccctgtcaca
    11941 tgggatatga actgtcttga ggaagtatgc ggcgcatgtt caatggtcat aaacggaaaa
    12001 ccccgccagt cttgcacggc gcttatcgac cagcttgaac agccgatccg tttaaaacca
    12061 atgaaaacat tcccagttgt tcgtgatttg caggttgatc gcagcagaat gtttgattca
    12121 ttgaaaaaag taaaagcgtg gataccgatt gacggtacgt acgatttagg accggggccg
    12181 agaatgccgg aaaaacgccg tcaatgggca tatgaattat caaaatgcat gacatgcggc
    12241 gtctgcctcg aagcttgccc gaatgtgaac agcaaatcga agttcatggg gcctgcaccg
    12301 atgtcgcaag tccgcctgtt taacgcgcat ccgacaggcg ccatgaataa atctgaacga
    12361 ttagaagcat taatggatga aggcggcctt gcagattgcg gcaactcgca aaactgtgtt
    12421 caatcctgtc cgaaggggat tccgcttacc acttcgattg cagccttgaa tagagataca
    12481 aacttacaag cgttccgcaa tttcttcgga agcgacagag tataagaaga aaaacctctt
    12541 ccgcatggga ctgacccccg tt
//
