LOCUS       gnlProkkaGNEHDOCD_20   15245 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GNEHDOCD_20.
ACCESSION   gnlProkkaGNEHDOCD_20
VERSION     gnlProkkaGNEHDOCD_20
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 20:24:51
            Original ID  :: gnl|Prokka|GNEHDOCD_20
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 76791
            Orig. end    :: 92036
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15245
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10375]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10375
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15245
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15245
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(28..693)
                     /locus_tag="ctg14_63"
                     /transl_table=11
                     /translation="MFEIKVSKEIKDACPVFAGAAVYAAVKNTAYSEGLWQEIDAFTGQ
                     LTSTTQMEDIKHQPVIFATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGTHLELGIGKAGEPFEGIGRGVLNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDLETTHILAIVNGYNGKEGLQEAVEMIQTLLRNYTESDGGEIVFFE"
     CDS             complement(744..1556)
                     /locus_tag="ctg14_64"
                     /transl_table=11
                     /translation="MISLTKHNELKGYKSLEAYPEVAHFVTTRHEGISTGAYGSFNCSP
                     YTNDSCMNVNRNQSWLFQCMNHQIKELFIPEQNHGCASLIINESFFKESLEMRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSNVMDHLNKMF
                     GTQGEDVIACIGPSISLESFEVGDEVYDAFEESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNLGVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRTLSGIMIRK"
     CDS             complement(1553..2716)
                     /locus_tag="ctg14_65"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVVLLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYEEDVDDDDDIDYEYEEEDWEEK"
     CDS             complement(2806..3375)
                     /locus_tag="ctg14_66"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             complement(3435..3971)
                     /locus_tag="ctg14_67"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(4012..5556)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 47.6; E-value: 1.5e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg14_68"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKVDHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVILAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(5750..5974)
                     /locus_tag="ctg14_69"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             6645..6761
                     /locus_tag="ctg14_70"
                     /transl_table=11
                     /translation="MRNTLKYYENKVAFEPKYGRTYEKYRFEKVFLIRYLFD"
     CDS             7036..8547
                     /locus_tag="ctg14_71"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPITSIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             8620..9687
                     /locus_tag="ctg14_72"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVSKKVAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDDK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             9724..10008
                     /locus_tag="ctg14_73"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(10001..10375)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_74"
                     /sec_met_domain="PqqD_RRE (E-value: 2.3e-10, bitscore:
                     32.5, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8.3e-17, bitscore: 53.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQYEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVVYRNLLLFI"
     CDS             complement(10473..11735)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 76.2; E-value: 3.2e-23)"
                     /gene_kind="transport"
                     /locus_tag="ctg14_75"
                     /transl_table=11
                     /translation="MLEKELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFT
                     GMGACLLMVFGCGLKYYAISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSK
                     IIVKWFKGKEMALAMGLEMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILF
                     CLIMLCVGTIAFFLYTFYDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCV
                     LFYSAVFPFIKYAADLMVQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATL
                     MIIGSVMLIFVHTMFALPILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGT
                     AYALIFWVQNWGLMGVPLLIGWVLNTYCKGLVVDGAQTYDYTLPMAIFALFGVLALIVA
                     LMLKAENKKKGYGLEEANIQK"
     CDS             complement(12111..12506)
                     /locus_tag="ctg14_76"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(12513..13286)
                     /locus_tag="ctg14_77"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFSGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQPAEEMPKLKGYELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(13292..13819)
                     /locus_tag="ctg14_78"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(13806..15047)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 386.3; E-value:
                     3.4e-117)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg14_79"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLTYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(15057..15245)
                     /locus_tag="ctg14_80"
                     /transl_table=11
                     /translation="MYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARANPLRKQYY
                     EKRDDSDKLKLDTVDED"
ORIGIN
        1 tcttttttct tagagcactc attctaatta ttcgaagaat acgatttcgc ctccatccga
       61 ttctgtatag tttcttaata aggtctgtat catttcaaca gcttcttgca aaccttcttt
      121 tccgttataa ccgttgacta tggctaggat atgagtagtt tcgaggtcca tcttcgtacg
      181 ttcatggtcg cttgtcgggg ttccgattcc gccgaaagaa tcacgatata caggtaatcc
      241 ttcgatattc aataccccgc gtccgatacc ttcaaacggt tctcctgctt tgccgatacc
      301 gagttcaaga tgcgtacctt gtattttgtc cgcgtcaaaa ccaccgatcg aatgtcccgt
      361 acgaagagac acaaggttga taaggtctac caacgtatca atctgatata aaggaattcc
      421 acgcatcagg cggcggcgta gagcttcggc tgacgggcgg taacgtccgg ggtctttgcc
      481 acaacgttta taagcctcac gggtagcaaa gataacgggt tgatgtttga tgtcttccat
      541 ctgtgtagta gaagtcagtt gcccggtaaa agcgtcaatt tcctgccaaa gcccttcgct
      601 gtaagctgta ttcttcacgg cagcatacac ggcggctccg gcaaaaaccg gacatgcgtc
      661 ttttatttct ttagatactt ttatttcaaa cataacttat cataaaccaa tcatcagcgt
      721 cctgcaataa cggacaccaa ttattacttt ctaatcatta ttcccgacaa tgtacgaccg
      781 gaatctattc ccagtctacg tgcagagaag aattcatcat gatgaatata ggtacagatt
      841 ccggccactt ctatctgttc tgcaggcact ccgagattca gtaattcaat ccggttggct
      901 tcccacaaat caatatgata tttgcctgtt tctttcttct tcatagaaat gagagacata
      961 tcgaagccgc tttcttcaaa agcatcatac acctcatcac ctacttcaaa tgattcgagc
     1021 gaaatgctcg gcccgatgca agctatcaca tcttcgcctt gcgtcccgaa catcttattc
     1081 aagtggtcca tcacattact gacaatatgc ttcaccgttc ccttccatcc ggcatgaacg
     1141 gcagccacaa cgtgttgttt tttgtcgtac agcaatacag gaacacaatc cgccgtcgtg
     1201 acacaaacgc aatatcccgg cacattagtt atcaaggcat ccattcctcg cagaagtagc
     1261 cgtctcattt ccaatgattc tttaaaaaat gattcattga taatcagact ggcacagcca
     1321 tgattctgtt caggaataaa taattccttt atctgatgat tcatgcactg aaacaaccag
     1381 ctctgattgc gattgacgtt catacatgag tcgttggtat aaggcgaaca gttgaaagag
     1441 ccgtaagctc cggtgcttat accttcgtga cgcgtagtta caaaatgagc tacttcggga
     1501 tatgcctcca gtgacttata tcccttcaac tcgttatgtt ttgtaagtga aatcattttt
     1561 cttcccaatc ttcttcttcg tattcataat cgatatcatc gtcatcgtcg acatcttcct
     1621 catattcata aacgatgtct tcatcttcgc ccatgtcttt gagttcctgt tgcagacggg
     1681 tcacgtcttt cggacggtga acgatgtcct ctatcttatt gctttccttg ttcagttctt
     1741 cccaaaggat gtctttcaac accgagatgc ccaaaccgga aacagaagat atgaatacat
     1801 gtggaatgcc ttccggcaat gtaggttcaa tctcgtccat caactcctga tcgagcatat
     1861 cacttttggt gacagccaac acacgttgct tgtccaacat ttcaggattg aaggtacgca
     1921 gttcgttcag caaaacttcg tattctttac gaatgtcgtc gctgtctgcc ggaaccataa
     1981 acagcagtaa tgaattacgc tcgatatgac gcaagaaacg cagtcccaaa ccttttccct
     2041 gactggctcc ttcgataata cccggtatgt ccgccatcac aaaggatttt ccaccgtgat
     2101 aggaaacgat gcccaagttg ggttcgagcg tagtaaacgg gtaatcggca attttcggtt
     2161 tggcagccga aatggaagaa agcaaagttg actttcccgc attcgggaaa cctaccagac
     2221 cgacatcggc aagcagtttc agctccatga taacggtcat ttcctgcatc ggctctcccg
     2281 gctgcgcaaa acgcggagcc tgacgggtgg ccgtcttgaa atgccagtta ccctgaccgc
     2341 cgcgaccgcc tttgagcaag accacttcct gtccgtcttc tgttacgtca caaagatact
     2401 cccctgtctc ggcattataa actaccgttc cgcagggtac ttctattatt ttatccgcac
     2461 cgtcttttcc gaaactacgt cctttgctcc ccgattcacc atgaccggcc attgcatgac
     2521 ggtcatactt caagtgcagc aatgtccagt aattacggtt accgcgcaag atgatatgac
     2581 ctcctcttcc accatcgccc ccatcaggac ctccgttagg acaatatttc tcgcgcctca
     2641 tgtgcgtaga gcctcttccg cccttacccg agcgacagta tatctttacg taatcaacaa
     2701 aattcgattc agccatattt ttttaaagag ttaaagtagt cagtagttag agcagttaat
     2761 tagaacactc cggctactga cttatttatt tataatattg tattattaca atttatctac
     2821 tgcttcgcag atttcagcga agataccttc catagtaccc aagccgttga tgtgttggta
     2881 tttcttttcg ttcttgtacc agtcgatcag tggagcagtc tgtgaatgat atacatgcag
     2941 acgtttcttg attgtctctt cgttatcatc agcacgaccg gaatccttgc cacgtttaat
     3001 gagacgtacc atcagttctt cttccggaac atccaggtca accataacag aaacgtcctg
     3061 tcctctttct gccaacattt tctttaatgc ttctgcctgt gcaattgttc ttgggaaacc
     3121 gtcgaaaatt acccctttac tatctttgaa gctgtcgaat acgcttgcca gaatatcaat
     3181 cattaattca tcaggaatca attgaccttg gtcgatgtaa cctttagctg ttttacccag
     3241 ttctgtgcca ttcttgattt cagcacgcaa tacatctcct gtcgagatgt gattgattcc
     3301 atacttttct acgatacgtt cgctctgtgt tccttttcct gaacccggag caccgaaaat
     3361 tacgatgttc aacattttgt tatttacaat ttaacgattt actatttacc atttaaactg
     3421 gtacctattt aatattaatc tactactgta taaatatcgg gataattacg tccgaaacca
     3481 tcataatcca gtccgtaacc tacgataaag tcgttcggga tttccatcgc tacatattca
     3541 atgttgaggt ttaccttgag cttttcaggt ttcaccaaca gagaagcgat atgaatagct
     3601 tcgggattgc gtgtacctaa tgtttcgagc agtcgctgca tcgtcagtcc tgtgtctacg
     3661 atatcttcta cgatcacaat ggtacgtccg gcaatgtctt cattcaggcc gattacctct
     3721 ttaatcactc cggtggaagt gatgccctga taagacgcca acttcacaaa tgagatttca
     3781 caagggatgg tgatgtgctt cagtaaatca gcggtaaaca tgaacgaacc gttcaacaca
     3841 ctaaggaaaa gcggattctt acctgccaaa tcgcggttaa tttcgttcgc tacgcgaatc
     3901 acttctttct gaatttcttg ttccttaata gaaacggtaa acaatttgtc ttttatctga
     3961 atggtatcca taaccggtaa tttaaaaata accttgcaaa aatacgattt tttattctac
     4021 cccgtgcatc atcttctgta atttcttcga gagaaggaac agaatcaacg aagcaacacc
     4081 ggacattacg acgaatacca taaagaaatc atacatggta gcaatctgat aaccaaagat
     4141 tgacttcact tttccggctt ccggatagag tccgctcaac attcccgcaa atttattggc
     4201 tgtggcagta gacagatacc agattcccat catcagggag gcgaaacgta gcggactcaa
     4261 tttatttacc attgaaagtc cgataggcga caaagctatt tcacccatgg tatgaataaa
     4321 gtaaagtcct gtcagccaaa tcatgctcac tttcactccg ggaacagcat ctttcactcc
     4381 gaaacagatg aaaagataac ctaaagaaag gagtaacaga ccaatcgctt gtttggtagg
     4441 agaagcaggt tccatctttc gcttgttcag gaaaccccat acacccggca tgatatatgc
     4501 caggataact acaaacaggg gattgaagga ttgaaaccat gaagccggca tttcccaacc
     4561 gaatatgtca cgattcgtct gttcggacgc aaaaagagtt aaagaagctc ccgcctgttc
     4621 gtaggctgcc cagaagaaga tgacaaagaa ggctactata tagataacga aaatacggct
     4681 gcgttctatt ttggtcaatg aaccgtctaa caggatcaga acagggaaaa caatgcaggc
     4741 ggtaaaaatg ccaatactca cccaatcgcc ttcaaatgca tagttaaaga aggctattaa
     4801 agcaatggta agaattgtga ttacaagggt attacgtact ttggtacgtt tgtccatctt
     4861 tgggtgtgag atatggtcga ccttgtcttc tttcttttca cgtttagcat cggggataat
     4921 accaatcggt tctccggaag gagaaaaaag atatttattc ttttgagtct cgaaaagaac
     4981 aacggtgaac agtgtcataa ttccggctgc aagaaatccc catttaaagt catgcggatc
     5041 accggtatca cccagataac cacaaatcaa aggagcagca aaagagccta cattcactcc
     5101 catataaaaa atggtgtatg cagcatccag ccgcctgtct ccgggttcgt agagctgacc
     5161 taccagagaa gagacagtgg gtttgaagca accattgccc agaatcagga agcctagtcc
     5221 gccatacatc atccagtggg caaggtttgt attatctaaa gtggaggcac tcataaacat
     5281 caggaattgt ccgactgcca tcatcaccgc tccccaaaac acggaacgac ggattcccca
     5341 atatttatcg gcaatgtatc cgccaatcaa cggggttaaa taaactagtc cggtatagct
     5401 gccgtagatg gatgctgccg cttctttgtc aaacaataat gcctgcgtca ggaaaagaat
     5461 aaagatcgca cgcataccgt aataactgaa acgttctgcc gtgcttgtcg cgaaaatcag
     5521 ataaaggcct ttcggatgcc ctttcaatgc actcatgaat ttatgtgttt agtagtttat
     5581 ggggtgcaaa ggtacagaaa aagtagatta gatgcttctc ttatcaaaca gaataatagg
     5641 gggaatagta aaaacgagca taaaaaatcc tactgatcca cttcattact tttttagcag
     5701 tgtaaataat aaagtggaga tccatcttaa atgtaggtta gctaccacct tagccaaaag
     5761 taaattcgac attttcgata ctggcaaaaa gcattccttc tcttttcctc aaaaagattt
     5821 tgtcttctcg ggccagccaa ccaatagcga gagctacgtc ttcaaacgtc aaacttaatt
     5881 cacggcacaa atcgaacatt gaaagttcac ctttttcatt taagatgcgc catactttcc
     5941 cggcattcaa gccaattttt gtcttttcca tcatgcaaac tttagaagat taaacaatcc
     6001 gttatttaga ttttaattca ttttcattgt gagcactgga aaatgatgtg atgcacatta
     6061 tctatctcca aagataacat ttttatcgga aacggcaaat aatcaaaggc ttaataaggg
     6121 gaaccgcatt aaaaatttgt ttaagaaggt atggcgataa actaaacaca atttccatcc
     6181 gcgcctctac agaaaaagat ttttcatttc tcatattctc ataaataaga aacaagtggc
     6241 agtaaactaa taagatagac tatgagaaat gatttaaaaa caggcatttc tcatagtttc
     6301 ttcgcaaaat aacccggatt ttgcttcatt tctcatagtg tagtgtgccg gaagctgaca
     6361 ttgaataaat aaaactatgt attccttttg cttgcttcca tacacagtgt cttagttcca
     6421 catattgtgg gaatagattc cctaaggctt gggaaagtat tcccttattt tgtgggaaag
     6481 tattcccgta tattgaagga aaactttccc acaatatatg ggacaatcga gaccaatgag
     6541 catcttcaag caaaaagcca ctattttatc taaatagtag cttcattccc tgataaaaat
     6601 aaggcaggct gaaagaaaaa aggaagaaca aatggctttt gactatgaga aataccctga
     6661 aatactatga gaataaggtg gcttttgagc caaaatatgg gagaacttat gagaaatacc
     6721 gtttcgaaaa agtgtttctc ataagatatc tatttgatta gctttcgttt atcgaaaaac
     6781 aatgagaata tgagaaatga aatgaagaaa tctttttcag gagaaataaa agtaagttca
     6841 taatggtgct gcattgaatt attttttggc ggagttattc taacacttaa tagttcaaaa
     6901 acagatattt ctctgaccaa aagatagaac taatgatgaa ttaaaagttg caattatggt
     6961 tttcttccca caacaaacgg gaaaagtcag aagaatcatg tacatttgta atccgaaaac
     7021 taaaagaaca tcgcaatgaa aatatttcca agcagcagta tcaagaaatt ggacgcttat
     7081 accattgaga acgaacctat tacatcaatc gatctgatgg aacgtgcagc aaccgtatta
     7141 acaaaagcca tcacagacag atggaatacg gaaacgccgg tcactatctt tgccggaccg
     7201 gggaataatg gcggagacgc tctcgccgta gcccgcatga tggctgaaaa aggatataaa
     7261 atcgaggtat ttctcttcaa cacgaaagga gaactttcac ccgactgcca gaccaataaa
     7321 gaactggtag aaatgatgga agaagtaaaa ttccacgaga tcagtaccca attcgtacct
     7381 cccgccctga cgcccgacca tctggtaatc gacggattat tcggttcagg cctgaacaaa
     7441 ccgttaagcg gcggattcgc tgccgtagtg aaatacatca attcctcccc tgctatggta
     7501 gtagccatcg acattccttc cggactgatg ggagaagaaa atacattcaa cgtaaaagct
     7561 aatattatcc gtgccgacgt aactttcagt ctgcaactgc cgaagctcgc ctttcttttc
     7621 gcagagaaca cggaatttgt cggagaatgg gaattgttgg atatccaatt gagcgaagac
     7681 ggcattgaag agatggaaac gaactacgaa atgttggaaa tagagcaaat ccgttcactc
     7741 atcaagccac gcaaacagtt tgcccacaag ggaaacttcg gtcatgcact attgattgcc
     7801 ggttcaaaag gaatggcagg agcctctgtt ctcgctgccc gcgcctgcct ccgttcggga
     7861 gtagggttgc tgactgttca tgcgccaatg tgcaacaacg acatcttgca gacctccata
     7921 cccgaagcaa tcgtagaaac cgatatcaac gaaacctgtt ttgccgtacc taccgatacg
     7981 gacgactatc aagcagtcgg catcggcccg ggactgggac gaaacgagga aacggaagct
     8041 gccttgttgg aacaactgga acactgccag actcctgttg tagtggatgc cgacgcactt
     8101 aatatcctcg ccaaccaccg tcatgcactt acccacctac cgaagggttc catcctcacc
     8161 ccgcatccga aagaactgga acgtctgacc ggcaaatgcc aggactctta cgaacgtctg
     8221 atgaaggcct gcgaactggc ccgtgccgcc catgttcaca ttattttaaa aggagcctac
     8281 tccgccatca tcacccccga aggtaaatgt ttcttcaacc caaccggaaa tccgggaatg
     8341 gcaaccggag gtagcggtga cgtactgacc ggagtaatcc tggcactact tgcccaaggt
     8401 tacccaaccg aggaagccgc aaaaatcggc acttacattc acggactggc gggcgatgtc
     8461 gctcaaaaga agcaaggaat gatcggaatg atcgcaagcg atattatcac ctgtctgccg
     8521 acagcatggc gacttgtaag cgaataaaag ttaagaagtt accctttttt caataacttc
     8581 attaactttg ttttcaaaac cagttaaaaa gaaccgaata tgaaaaagtt gattatagca
     8641 gcaggactac ttatgacaac gtccgcctat gcacaaaccg aagtactgac aggggttacc
     8701 cgaggaaaag actatggagt ggtttacagt cttcccaaaa cccaaataga acttgaaata
     8761 aaagccaaca aagtcaacta tactcccgga gaattcagca aatatgctga tcgttaccta
     8821 cgactgacca acgtctccgc cgaccctgaa gagtactggg aactggctag cgtaaaagtg
     8881 aaatccgtag gtgtgcccaa cagcgaaact acgtatttcg taaaattgaa ggataagaca
     8941 gtagcaccgc tcatggaact gacagaggat ggcattgtga aaacgatcaa tgttccttac
     9001 agcaatagca gtgtaagcaa aaaagttgct cccgctcccg cagtcctcca aaagaaagcg
     9061 aatcctcgcg aattcctgac cgaagagatt ctgatggcta gttctaccgc caagatggcc
     9121 gagctggtgg ctaaagaaat ctataacatc cgcgaaagca aaaatgcctt attgcgcgga
     9181 caagctgata atatgccttc agatggggca cagcttaaaa ttatgctcga caatctgaat
     9241 gcacaggaag aagccatgac gcaaatgttc tccggcacct gcaacaaaga agagagaaca
     9301 ttcactgtcc gccttacccc tgacaaggaa ttcaacaatg aagttgcctt ccgcttctcg
     9361 aagaagttag gtgtagttgc caacaatgat ttggcaggaa ctccgtttta tatcagtctg
     9421 aaagacctga aatcggtcaa gataccacag gaagacgata agaagaagaa agatttggat
     9481 ggaatcgcct acaacgtacc cggacaagct atggttacac tgactgacgg taaaaagaaa
     9541 ctttacgaag gtgagcttcc tattacccaa tttggtgtga tagaatatct ggctccggtt
     9601 ttgttcaaca agaattctac catcaaagtt tattttgatc cgaatacggg aggattgctc
     9661 aaagtggaca gagaagaagg gaaatagaaa aacgaggaag tgaacttcta aaaaacaaag
     9721 aatatggttg gtgaaggaca tgcattcgac atgatacgcc gaataaaaga gggacgggaa
     9781 gcttcccgcc tacgtcgtga acgtgctaac gataagttga agcatttaaa ccgtgcaaac
     9841 gaaccttatc cactacccaa caccaccccc gaagaaatgg aacgtatcat ccacgactcg
     9901 gagaaaaaga aagagaaaga cagcaattat tttgtttggg gaacgcttat tatcatgggg
     9961 gtcctgatag caattgccgt catactttgg gctgtattta tcaaataaat aataataagt
    10021 tcctatatac gactggtatc accagtttta taaatccatc tttctgcatt tgagaaagat
    10081 aagccgatac acgcgactcg tagccctctt catattgaaa gtggtctgcg agtttttcta
    10141 taatctcacg aacattgcgt tttccatcta tcagttccca tacagccgta ccgtgttctt
    10201 ccaatttcac atgaagttct ttcgacattc ctttcggcac aaggaagcgt tgcatccacg
    10261 gatatttaaa acggggaaag gagagcacaa ttgtctcccc ttccctttct gctgtaatat
    10321 gttcactgcg acagggaatg acctctaaca ggttgatttt ctctttggca gccatacttc
    10381 ttatttttta tttcagagta ttcatactga tacccttttg tttacacctt gatacaaaat
    10441 tcctttgtta ctttaggtat tgaatttcct agttactttt ggatattcgc ctcttccaga
    10501 ccgtatccct tcttcttgtt ctctgccttt aacatcaaag ccacaatcag agcaagcaca
    10561 ccaaagagag caaaaatagc catcggcaac gtgtagtcat aagtctgtgc accgtctact
    10621 accagacctt tgcaataagt attcaacacc catccgatca acaaaggaac acccatcaat
    10681 ccccagttct gtacccagaa aatcaatgcg tatgcggtac ccaactgttt ttccggaata
    10741 atcttcggaa cagacggcca catagctgaa ggcaccaacg agaaggcaaa tcccaatata
    10801 atcatgataa tagtagcaaa ccaccatata ttcagtatag gcagagcaaa catcgtatgc
    10861 acaaaaataa gcatcactga tccgattatc atcaatgtgg ctcccttacc gatacggtca
    10921 taaagcgagc cgaacaacgg agtcaggata atcgcaccaa tcggcaacaa tccgggaatc
    10981 gttcccgcca acttcggatc tacattatac ttctgcacca tcaagtcggc agcatacttg
    11041 ataaagggga atacagccga gtagaacaat acacatagta atgcaatcag ccagaatcct
    11101 ttattggtaa tgatatacac aatatctttc atacggaacg gctcttccgg ttccaatccc
    11161 tctgcatcca aagaagcatc caacttctta tcatagaaag tataaaggaa gaaagcaatc
    11221 gtacccacgc acaacataat cagacaaaac aaaatcggag caggaatatt ggtatgaaat
    11281 gtgccactct catccgtaga tccgaaaaag tcggccaaag gaaccgtgag caccattgcc
    11341 agagttgttc cgatacgtgc cgtagccatt tcaagtccca tagccaacgc catttcctta
    11401 cccttgaacc atttcacgat aatcttggaa actgtgatac cggcaatttc cacacctaca
    11461 ccgaagatag cataccccaa tgcagccagg gttacctgtg ttttgaatcc gaagagcatg
    11521 gcaccttccg gaaaagtagt agaaatcgca tagtatttca atccacaacc aaacaccatc
    11581 aataagcaag cccccattcc ggtgaaacga actcccatct tatccaaaat gataccaccg
    11641 aaaatcagca tcaataggaa tacattaaac cacccgtaag cgcttgtgaa gaaaccataa
    11701 tcaagactgt cccatagtag ttctttctca agcatgggtt ttagaggaga cattacgtcg
    11761 gtgaggaaat agccgcatag catagtaaat gcgactaatg ctagaacact ccatcggagt
    11821 acggcggagt cattcaattt ctgtttcaaa tgttctgtca ttgttatatt taaaaatagt
    11881 agttaataat cttcatacga ccaacaaagg tagttaaatc tcgtttgttt ctatcaaaaa
    11941 gagattgttt ttacaagaaa aagttaagtg cggattacac tgaccacgcg gaagattgaa
    12001 aatccgtgta atctgcgtaa tccgcactta aatatcaaag aaatgcagca tccgtctgca
    12061 ccttcccatt aatggtttta ccccaaagtc ttacctgaca acggagtgaa ttactctgct
    12121 gcaggagcag gagtttcagt agccggtgcc ggagtttctg tagcaggtgc attggtagca
    12181 ggagcttcag tttgcggcgc agccgtacct gcgggtaagt tatacgggtt agtctgttgt
    12241 tctttctgtg cctgttccaa cactgcgtct ttagcaacag cagagcgagg aactacataa
    12301 gcagtagcaa tgctcattac caccatgaag atagctaagc cccatgttgc tttttccaga
    12361 aaatctgtag tcttgcgcac gcccatgatg gcgttagatg aagagaaacc agaagcaagt
    12421 ccgcctcctt ttgagttctg aatcagcacg atgaaacaca tcaacaaggc tgcaataacc
    12481 attaagataa cgaataataa gtacattttt agttattttg aattagcgtt aataatcaat
    12541 ttctccaaaa atctgatttg atctgcaaag taagcatttt tttttggata tttcaagctt
    12601 aattttttaa ttatttcaag agcttttgaa tatcgttgct gtttaacata gatttttgcc
    12661 aaagtttccg taaaacagct gtcatcttcc tcttcttcct tcatcgtttc ttcttcggta
    12721 agttcgtccg aagaggttgg cgaagatggc atttcttctc ttaaaggttt catgcagagg
    12781 ggagagtcgc tctcgctctt ttctataaag tcgtcaatca gttcgtagcc tttgagtttg
    12841 ggcatttctt cggccggctg ttccgtggcc ggagtctcct ccaaaagata agaagtgtaa
    12901 tccatcgaat agtcgaagct ggtccgggca gtcacctctt cgggtactgt ggacaagaaa
    12961 gcgtcgatca gtgctaatgt gcggtctacg gacggttcgt ctttcagcac ctccgtgaga
    13021 ggtactccct ttttccgtgc ttgcacatca tagcggtcac cttcaatcaa ccggaacaac
    13081 tgccgtctgt ctgcaatgta aagaactgct ttccgcagtt ctccactgaa actaatatca
    13141 tggagaatat acagattctt cagatacagc agacgaagtg actgaaaata cggatacctc
    13201 gcaagaagat tgcgcagttc gtacaaagta tccctattca gcgtctcggg atgctgaatc
    13261 cattgttgaa agttaacaga agtcatttat attaccagtt tgctacagtt gcattaaaaa
    13321 tttggtcggt gatctcttta gacatttcag caatcaatcc gtcctgtacg gcagtcagca
    13381 actggctaga gtcgtaggta cggaacgcag aaaactgttg ttcaaagtct tcggcatgat
    13441 tggtgttgtt gacaaaacgc acattgacgg tgatagtcaa cttcgtctcc gaagaataac
    13501 cgtcggcaga tactgcctgg ttgtactgat tgtaccctgt gatttctccg tcaatctgca
    13561 agtcggcatt ttgactcggc ttgagcagtt gcagacgggt ctgccggatg aagatatctt
    13621 tcaggtcctc attgaatttg gttgccaacg gagcatatac atactccgac ttgatcggga
    13681 agtcggctat cgaaatggtc tttaccttat cataattgat agacgatccg ttaaacttat
    13741 aggaaacagt gcacgcaatg actaccaacg gcaagccgaa cagtagcaaa gggcgtatta
    13801 ttttcttaat ccaattcata ttcttttatt tttctataaa gtgtacgctc ggaaatattc
    13861 aagtccttgg ccgcactctt ccgctttcca tgatgcctct caagtgcctt gcgtatcatt
    13921 tctttctcca cttcgtccag tgacaaagga gattcttcta catattcttc cgtgtcttgt
    13981 atgtcatcgt catccttgca aaccgtaggc tgcatggtgt gaatgatagc aggtaccgaa
    14041 ggttgatgcg ccgtcactac cggagtagta accaccgttc ccatttgccc tacctgcccc
    14101 acctgtccgg cacgttccgc catcaggttg tgcaccatct tcttcagctc cgccacttcc
    14161 tggcgcatat cgaacagaac agaataaaga atctcccgtt cgctctcaaa gcctttactc
    14221 tcacgcgttc ccatcagcgc gggaagacgt tgcgtatttt gtgcaggaag ataattctgc
    14281 aagatagcag cagagatctc cctgttggtt tcaatgatag atatttgctc ggtgatgttc
    14341 ttcaactgac gaacgttgcc gggccacggg taagtcaaca actctttctt cgcatcctcc
    14401 gtcaactgga tagcaggcat ccggtatttc tctgcaaagt ctgcggaaaa cttacggaac
    14461 aacaaaagta catcgtcacc acgttcacgc aaaggcggta tttggatagg caccgtattc
    14521 aaccggtaat ataaatcttc acggaaacgt ccttctgcaa tcgcttgtgt aagattgaca
    14581 ttggtagctg ccacaatacg aacatccgtc ttttgcactt tggacgaacc tacttttata
    14641 aactcgccac tctccaacac acggagcaaa cgcgcctggg taggcatcgg caactcccct
    14701 acttcatcaa ggaaaatagt accaccgtcg gcttcgccaa agtacccttt ccgttcgcca
    14761 atcgcaccgg taaacgcacc cttctcatgc ccgaacagtt cggaatcaat cgtgccctcc
    14821 ggaatagcac cacagttgac agcaatatac tgtccgtgct tcctccggct atattgatga
    14881 ataatctgcg gaaaactttc ttttccgact ccactttctc cggtaatcag cacagacaaa
    14941 tcggtaggag ctacctgaat ggcaacatct atggcgcgcg acaatgcttc ggtattacct
    15001 ataataccga aacgttgttt cacttgttgt atctctgctc ttgtcatcac tcgtttttaa
    15061 tcttcgtcta ctgtatccag cttcagttta tcactatcgt cacgtttctc gtaatactgt
    15121 ttacgcaacg gattggcacg agccactttt tcccgctgac gattacggaa cacgtcgatg
    15181 gcaacataga ttgcctgacg gaaagaatct tcacaagcca ctcccttgcc tgcaatatcg
    15241 tatgc
//
