LOCUS gnlProkkaGNEHDOCD_25 13521 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|GNEHDOCD_25. ACCESSION gnlProkkaGNEHDOCD_25 VERSION gnlProkkaGNEHDOCD_25 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2024-11-30 20:24:51 Original ID :: gnl|Prokka|GNEHDOCD_25 NOTE: This is a single region extracted from a larger record! Orig. start :: 1926 Orig. end :: 15447 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..13521 /aStool="rule-based-clusters" /category="other" /contig_edge="True" /core_location="[5000:8521]" /cutoff="20000" /detection_rule="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))" /neighbourhood="5000" /product="phosphonate" /protocluster_number="1" /tool="antismash" proto_core 5001..8521 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))" /neighbourhood="5000" /product="phosphonate" /protocluster_number="1" cand_cluster 1..13521 /candidate_cluster_number="1" /contig_edge="True" /detection_rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))" /kind="single" /product="phosphonate" /protoclusters="1" /tool="antismash" region 1..13521 /candidate_cluster_numbers="1" /contig_edge="True" /product="phosphonate" /region_number="1" /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))" /tool="antismash" CDS 1122..2258 /locus_tag="ctg19_3" /transl_table=11 /translation="MSTLMEQTSEKETKQLHNNHNDEEIEIDLMDLLRKVIGIRKKIYK AAGIGLIIGVIVAISIPKQYTVEVTLSPEMGNNKGGGLSGLAASFLGSGVSMGDGTDAL NASLSADIVSSTPFLLELSNMKVPVSGSEKISLSSYLDEESSPWWSYVIGFPGMVIGGV KSLFIEDEDESIFSDKASQGTIELSKKESQKIESLKKKIVASVDKKTSMTSVAATFQDS KVAAVVADSVVKKLQEYIIDYRTSKSKEDCIYLEKLFKERQQEYYVAQKKYADYMDSHD NIILQSVRTEQERLQNDMSLAYQVYSQVASQLQIARAKVQEEKPVFAVVEPAVVPLEPS GTSRKVCVLAFIFLSVCIVISWNLFGKDFLNKFKEVCA" CDS 2278..3690 /gene_functions="biosynthetic-additional (rule-based-clusters) Bac_transf" /gene_functions="biosynthetic-additional (smcogs) SMCOG1146:sugar transferase (Score: 294.9; E-value: 1.9e-89)" /gene_kind="biosynthetic-additional" /locus_tag="ctg19_4" /sec_met_domain="Bac_transf (E-value: 1.1e-68, bitscore: 222.5, seeds: 461, tool: rule-based-clusters)" /transl_table=11 /translation="MVSTTSQINKFIEFVAVLGDLIILNLVLFFLLFFWEEVFVSLPFS CRVSWMMTSLSLCYLACSGSRGRVWDSRGIRPDQLVLRVLKNIIAFSIFWACIMTFSGI SIYSPLFFVAYFSFLFVILSIYRIIIRHFLIVYCAKGKHRRYAVFIGGGNNMQVLYEEM ESSLASSLYEVVGYFDIKPNEAFSSQCSYLGNPDGFSDFMSVHPGIKHVFCSLSMEEGR YNFSIMNHCENHLLYFHGVPNVCKGFPRRIWHSMVGNMPILNLRYEPLGKMENRILKRI FDIVISGLFLVTIFPFVYLIVGSIIKLTSPGPVFFKQMRTGLNGVDFVCYKFRSMKVND EADSKQATADDPRKTRFGDFLRRSNIDELPQFINVFKGDMSVVGPRPHMLAHTEIYARL IDKYMVRHFIKPGVTGWAQTHGFRGETRELSQMEERVKADIWYMEHWTMLLDIYIIYKT VANVIVGEKNAY" CDS 3752..4879 /locus_tag="ctg19_5" /transl_table=11 /translation="MNHYDFLIVGAGLFGSVFAYKAKLQGKKCLVIDRRSHLGGNIYCE NIEGINVHKYGAHIFHTSNKVVWDFVNSIVEFNRYTNSPIASYKGKLYNLPFNMNTFYQ MWGITTPAEARAKIEEQKAEAIALMKEQGVIEPRNLEEQAQLLIGKDIYELLIKGYTEK QWGRKCSDLPAFIIKRLPVRFIFDNNYFNDKYQGIPIGGYNVLIERLLEGIDTKLNYDF FAHRNELEEISDRIVFTGAIDEFYRYRFGKLEYRTVNFETELLNMSNYQGNAVINYTEK EIPYTRVIEHKHFEMFGADIEACSKTVISKEYSSEWKEGSEPYYPVNDEKNNSLYLKYK KLADQDNNVIFGGRLAEYRYYDMHQIVTKALSHFK" CDS 5001..6284 /gene_functions="biosynthetic (rule-based-clusters) phosphonate: CTP_transf_like" /gene_functions="biosynthetic (rule-based-clusters) phosphonate: phosphonates" /gene_functions="biosynthetic (rule-based-clusters) phosphonate: PEP_mutase" /gene_functions="biosynthetic-additional (smcogs) SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 202.1; E-value: 1.8e-61)" /gene_kind="biosynthetic" /locus_tag="ctg19_6" /sec_met_domain="CTP_transf_like (E-value: 1.2e-13, bitscore: 43.7, seeds: 65, tool: rule-based-clusters)" /sec_met_domain="phosphonates (E-value: 8.7e-118, bitscore: 384.7, seeds: 8, tool: rule-based-clusters)" /sec_met_domain="PEP_mutase (E-value: 2e-61, bitscore: 199.7, seeds: 69, tool: rule-based-clusters)" /transl_table=11 /translation="MSADIIHPGHLNIIHEANKLGRVVVGVLTDSAIASYKRLPYLSFE QRSLIVENLKGVDEVIPQTTLDYVPNLEKIRPNYVLHGDDWKEGVQQKTRQHVIDCISQ WGGKVIDIPYTQGISSSLLNQHLKEIGTTPEVRMKRLRRLIAAKPIVRILESHSGLTGL IAENACIEINNVKREFDGMWASSLTDSTSKGKPDIEAVDLTTRLHGLNDALEVTTKPFI YDGDTGGKLEHFVFTVRTLERLGVSAVIIEDKVGLKQNSLFGTDAIQTQDTIEGFTAKI KAGKNAQITEDFMIIARCESLIAGKPMSDAIERCFAYVEAGVDGIMIHSKEKTGEDIKE FCKKFRARYADIPIVVVPTTYNQFTEEELASWGINVVIYANHMLRASYPAMMNCAKSIL THGRSKEASAEYCMPIKEILELIPSTHK" CDS 6294..7418 /gene_functions="biosynthetic (rule-based-clusters) phosphonate: TPP_enzyme_N" /gene_functions="biosynthetic (rule-based-clusters) phosphonate: TPP_enzyme_C" /gene_functions="biosynthetic-additional (smcogs) SMCOG1055:pyruvate oxidase/decarboxylase (Score: 62.4; E-value: 5.9e-19)" /gene_kind="biosynthetic" /locus_tag="ctg19_7" /sec_met_domain="TPP_enzyme_N (E-value: 3.4e-20, bitscore: 64.5, seeds: 75, tool: rule-based-clusters)" /sec_met_domain="TPP_enzyme_C (E-value: 7e-21, bitscore: 66.8, seeds: 323, tool: rule-based-clusters)" /transl_table=11 /translation="MISPKFFIDELDRYGIDYFAGVPDSLLKSICGYIADNMDARHNII TANEGAAVALAAGYHLATGKVGVVYMQNSGEGNAINPLASLVDKEVYNIPILLLIGWRG CPGVQDEPQHVKQGKVTTGLLNIMGVNYDVLSKEENKAAKQILKAVEAVKRNEVYALII EKDTFNAYTLQNVERNNFTMSREEAIQTVVAALGEADTIISTTGMISRELFEYRTAMNQ GHERDFLTVGAMGHASQIALGIALEKQDRKVWCFDGDGASIMHMGSMAIVANKAPQNYV HVVFNNGAHDSVGGQPTVGLKIDIPAIAKAMGYKHVYNVDTKEGLQELIGEIKVQEGPI FLQACVKQGNRKDLGRPTTTPIQNKEALMTFLRS" CDS 7430..8521 /gene_functions="biosynthetic (rule-based-clusters) phosphonate: Fe-ADH" /gene_kind="biosynthetic" /locus_tag="ctg19_8" /sec_met_domain="Fe-ADH (E-value: 5.1e-67, bitscore: 218.3, seeds: 218, tool: rule-based-clusters)" /transl_table=11 /translation="MQIIYQGIDYLNEALKGSTKVLLVCGSSFPYLGIKDKIEHIGTPF MVFDQFTSNPLYEDICRGVDLFQITQCDTILAIGGGSSMDVAKCVKLYCQMSKDKPYLQ QEYKDTGVKLIAIPTTAGSGSESTCYAVIYHDGKKQSVMHKSIIPDVVILEPKLLKTLP VYQKKCTMLDALCQGIESWWSVNSTDESKRYSKIAVETIIKYWREYIFENTDFSAEQIM LAANYAGRAICITQTTAAHAFSYKITSLYKLPHGHAVAVGLSEIWEYMLLNMNKCLEPR GEEYLWGIFADISKAMGCLTLEQAVVKFRQILTEMEITNPVAINKTEEIEILSHSVNPV RLKNNPVELCEFTIKSLYEIIIK" CDS 8597..9577 /locus_tag="ctg19_9" /transl_table=11 /translation="MTQYINSLEEEMRSGFLVTRQSKHVWNIQIEMTLALLEVCKKYNL RIWAISGTMLGAVRHKGFIPWDDDMDFFMFREDYDRLLEIASDEFKKPIFFQCAYTEKG YYRGHAQMRYDNTAMILLYEGEIGVKFHQGIFIDIFVADGFPEDKEEREQLIEQRNCIL NYLWGRNYPLRRFSSIPNLIKYISAKRKLGEKASWTDIELYSYMEQLHRNYSVNRNSRN CCIQFTYLPRYVRNTEWFDETVWIPFERIELPVPLAYHEVLKHEYGDYMKPIKGASLHG NLVVDVDESYEKYLSGLKMSFLKATYLFIKSGGGMVLRVFGLRKK" CDS 9602..11029 /gene_functions="biosynthetic-additional (rule-based-clusters) Polysacc_synt" /gene_kind="biosynthetic-additional" /locus_tag="ctg19_10" /sec_met_domain="Polysacc_synt (E-value: 4.1e-39, bitscore: 126.8, seeds: 31, tool: rule-based-clusters)" /transl_table=11 /translation="MKDKAVNGVFWTSVERIGSQVLSLLVGIAVARILSPEDYGIIGMT AIFLAVASTLLDSGFGSALIQNQNRTETDYSTCFYFNIVVGLFWYVVLFLAAPLIADFY RTPLLESVCRVLGLVFVFNSLTISQTARLTVEFRFRELCFVTLGTQLLTGIVGFIMAFK GYGVWALVFQQVGAAFLRVCLIEWITHWKPLPLFSKIAFCRMFSFGSKILCSGIINTVY DNIYTLVIGRVFSPVEVGFYNRGNQFAQLPSQSLLSVVMKVVYPLMAEVQDDSEKLCRA YQKFLRISVFILYPILIGLIVLAESFIYVLLGDKWLPCVPLMQILCFSYLFDPLTHINL NILYVRGRTDLVLKLELIKKPIALIILFGMLPFGLWWLCAGRALYSFIAYCFNCFYTGK FIRFGFRQQMYYSVPVIVKSALMGIICWRTALGFEEPWLKLMVGFLAGLLSYIGLNFIS HDESFFDIKGIILKNGK" CDS 11044..12060 /gene_functions="biosynthetic-additional (rule-based-clusters) Glycos_transf_2" /gene_kind="biosynthetic-additional" /locus_tag="ctg19_11" /sec_met_domain="Glycos_transf_2 (E-value: 3.6e-27, bitscore: 87.5, seeds: 256, tool: rule-based-clusters)" /transl_table=11 /translation="MNKILSVVIPSYNMEEYLYRNVSSMMIGEILDDLEIIIVNDGSKD RTSEIAHELQRKASQSIVVIDKENGHYGSCVNAALKIATGKYFRILDADDWMDSGEFVK FVNILKCIDVDCIYTPFANVFFNKNRKEYCIADNAVWNKKIDLSHVSLPPSYFHMHSLT YRTHLLHKISFVQEEKICYTDSEYVFYPLSHAKSLYCINVCPYQYYIGREGQSVSLDSL SKNYAHFEKVLANISFYKPMELLPTYSSLRKYYIVTLLRYMLDIHLFSQKKDVQRDKLL RDKIRAFGDDVNISEQIKDINLKGLHYINWWLDNTGVDKLKLKILVLLKKVQHTIVN" CDS 12062..13027 /gene_functions="biosynthetic-additional (rule-based-clusters) Glycos_transf_2" /gene_kind="biosynthetic-additional" /locus_tag="ctg19_12" /sec_met_domain="Glycos_transf_2 (E-value: 2.3e-27, bitscore: 88.1, seeds: 256, tool: rule-based-clusters)" /transl_table=11 /translation="MPKISVIIPVYKVEQFIERCAISLFEQTLDDIEYLFIDDCSPDNS VEIIKNVLMRYETRKDSVRIISMQKNCGQAAVRRYGNSIARGDYIIHCDGDDWVDINMY YKMYECAVNNKLDIVRCKFCRTDGKLMKECINIPSNIYCDAKKMISYLLRLSDLSSTCD KLVRRELYQSVDFIYPVDNMCEDFAIVTQLFCRTDKIGYIDEVLYFYYQNKFSISHILD NTHIDNKAQQISNNVKLIGKILKTKYPGGIFDKEIEVIKLMAKNAYRPIIRREGYYEKW KTLYKEINSKIFFNEYITIKEKLSFIACYIGIYPLLTGRK" ORIGIN 1 atcgccaacg tgaggatctt actactgaag ttatccctgt tgacattaaa gccattatgg 61 atggtacttc tcaaaatatc atcctagcga aaaacgacat tctttatatt cctagtatcc 121 atgatttgga agatagaggt gatgttgtaa tccatggtga agtggccaaa ccagattcct 181 atccttatgc tgacaacatg actcttgaag acttgatcat tcaggccgga ggcttgcgtg 241 aagccgcttc tgtagttcgt gtggatgtat cccgtagaat caagaatccc cgtagtacag 301 tggataacga tactattggt cagatctata cattctccct gaaagaaggc tttgtcgtcg 361 acggcacacc gggtttcgta cttcaacctt atgatgaggt ttatgttcgt cgtagtccgg 421 gttatcaggc tcagcagaat gtagccgttg aaggtgaaat cctgttcgga gggtcttacg 481 ccatgactag tcgtgaagaa cgtctttcag atttgatcaa taaagcggga ggtgctacga 541 attatgctta cttacgcggt gccaagttga ctcgtgtcgc tactgcaggt gagaagaaac 601 gtatgggaga tgtgatccgt ttgatgagtc gacagctagg agaagctatg atggattctt 661 tgggcgtccg tgtggaagat cattttacag tcggcattga tttggagaaa gctatagcta 721 atcctggcag tgcatcagat ttggttcttc gtgaaggtga tgtggttttt attccgaaga 781 atactaatac ggtcacgatc aatggtgctg tcatggttcc gaatacggtt tcttatatag 841 aaggacagaa agttgattat tatttgaatc aggccggtgg ttattctgaa aatgcgaaga 901 agagcaagaa gttcattgtt tatatgaatg gtcaggtaac taaggttaaa ggtagcggta 961 agaaacagat cgaaccggga tgtgagataa ttgtgcctag taaggctaag aagaagacca 1021 atatgggaaa tattttaagt tatgctacta cattcagtac tttgggtatg atggttgcct 1081 ctattgctaa tttaatcaag aaataacgaa tacctttatt tatgtctact ttgatggaac 1141 aaacatctga gaaggaaaca aaacagttgc ataataatca caatgatgag gagatcgaaa 1201 ttgatttgat ggatcttctt cgtaaggtta taggtattcg taagaaaatc tataaagcgg 1261 ccggtatcgg actgataatt ggtgttattg ttgcgataag tatccctaag cagtacacgg 1321 ttgaagttac cctttctccg gaaatgggta ataacaaagg tggtggttta tccggtttgg 1381 ctgcttcatt tttaggaagt ggagtttcta tgggagatgg aaccgatgcc ttgaatgctt 1441 ccttatctgc agatatcgtc tcttctactc ccttcttgtt ggaactttct aatatgaaag 1501 tacctgtatc agggagtgag aaaatctctt taagttctta tttagatgaa gaatcttctc 1561 cctggtggag ttatgtaatc gggtttcctg gtatggtaat tggcggagta aagtctttgt 1621 ttatcgaaga tgaggatgaa tctatttttt cggataaagc gagtcaaggt accattgaat 1681 tatctaaaaa ggaatctcag aagattgaat cactaaagaa aaagattgtc gcttctgtgg 1741 ataagaaaac ttcaatgact tccgttgctg caacttttca ggattctaaa gttgctgcag 1801 tcgtagccga ttccgtggtt aagaaattgc aggaatacat catagattat cgtacttcca 1861 aatctaaaga ggattgtatt tatttggaga aacttttcaa agaacgtcaa caagaatatt 1921 atgtcgctca gaagaaatat gctgactata tggactctca tgacaatatc attttgcaga 1981 gtgttcgtac cgaacaggaa cgtttgcaga atgatatgag ccttgcttac caggtataca 2041 gccaggttgc cagtcagctt cagattgcca gagctaaagt tcaggaagag aagccagtgt 2101 ttgctgttgt agaacctgct gttgtcccct tggaaccttc gggaaccagt aggaaagtat 2161 gtgttttagc ttttattttc ctatcagttt gtattgttat ctcttggaat ctattcggaa 2221 aagattttct gaataagttc aaagaagtat gtgcctaaaa tcaattttta atgtgatatg 2281 gtatcaacca ccagtcaaat caataaattt atagaatttg tagcagttct gggagatctg 2341 atcattctga acctggtatt gttctttctc cttttctttt gggaagaagt atttgtctct 2401 ttaccttttt cttgcagggt ttcatggatg atgacttcgt taagtctctg ctatctggcc 2461 tgttctggat cccgtgggag ggtgtgggat agtcggggaa ttcgccctga ccaacttgtg 2521 ttgcgtgtgt tgaagaatat tatagctttt tccatctttt gggcatgtat catgactttt 2581 agtggaatct ctatctattc tcctcttttc tttgttgcct atttctcttt cctctttgtt 2641 attctaagca tttatcgcat tattatccgt catttcctga tagtctattg tgctaaaggc 2701 aagcatagac gttatgctgt ttttataggt ggaggcaata atatgcaggt gttgtatgag 2761 gagatggaga gttctttagc ctcttcccta tatgaggttg tgggttattt tgatataaaa 2821 ccgaatgaag ccttttcctc ccaatgttcc tatctgggta atcccgacgg tttttcagac 2881 tttatgtccg tacatccggg aatcaaacat gttttttgtt ctctgtcgat ggaggagggg 2941 cgctataatt tttctattat gaatcattgt gaaaaccatt tgctttattt tcatggtgtt 3001 cctaatgtat gtaaaggttt tcctcgtcgt atctggcaca gtatggttgg caatatgcct 3061 atcttgaatc tgcgttatga gcctttgggt aaaatggaaa atcggatatt gaagcgaata 3121 tttgatattg ttatctcagg tctttttctg gttactattt ttccttttgt ttatctcata 3181 gtgggaagta ttataaaatt gacttctccc ggtcctgtat tctttaagca aatgcgtacg 3241 ggtttgaatg gtgtggattt tgtgtgttat aaattccgtt cgatgaaagt gaatgatgaa 3301 gccgacagta aacaggctac ggctgatgat ccccgtaaaa caagatttgg agatttcctc 3361 cgtcgttcta atattgacga actccctcag tttatcaatg tctttaaggg tgatatgtcg 3421 gtagttggtc cccgtccaca catgttagcc catacggaga tttatgcccg tttgattgat 3481 aaatatatgg tgcggcactt tataaaacct ggagtgaccg gttgggctca aacgcatggt 3541 tttcgtggtg aaacgaggga attatcacag atggaggaac gtgttaaggc tgatatctgg 3601 tatatggagc actggacaat gctgcttgac atatatatca tttataagac tgtggcgaat 3661 gtgattgtgg gggagaagaa tgcgtattag aagaggggat attaacgaat ttaaatgtat 3721 ttcgtaatat agaaataaaa ttagaaatgt catgaatcat tacgatttct taatagtagg 3781 tgccggactt tttggttccg tattcgccta taaagcaaaa ctacaaggta aaaagtgttt 3841 agttattgat cgccgttctc atttgggtgg gaatatttat tgtgaaaaca tagaaggtat 3901 taatgttcat aaatatggag cacacatttt tcatacttcc aataaagtag tgtgggattt 3961 tgtaaattcc attgtggaat tcaatcgcta taccaattca ccgatagcta gctataaagg 4021 aaagctgtat aatttacctt tcaatatgaa tactttctat cagatgtggg gaatcactac 4081 tcctgctgaa gcaagggcaa agattgaaga acagaaggca gaggcgattg ctctcatgaa 4141 agaacaaggt gttattgaac ctcgcaactt ggaagagcag gcacagttac ttatcggaaa 4201 ggatatttat gaattgctga ttaagggtta tacagaaaaa cagtggggac gcaaatgtag 4261 cgatcttccc gcattcatca tcaaacgact tcctgtacgt tttatttttg ataacaacta 4321 ttttaacgat aaatatcagg gaattcctat cggtggatac aatgtactga tagagcgctt 4381 gctggaaggt atagatacca aactaaacta tgatttcttt gctcaccgga atgagttgga 4441 agaaatttca gataggatag tatttacagg agcaatagat gagttttata gatatagatt 4501 cgggaagttg gaatatcgta cagtaaattt tgaaacggag ctattaaata tgtccaacta 4561 tcagggtaat gcagtaatta attatacaga aaaagaaatt ccctatacac gtgtcattga 4621 gcataagcat tttgaaatgt tcggggcgga cattgaggct tgttctaaaa ctgttatctc 4681 gaaggaatac agttcagaat ggaaagaagg gagcgaacct tattatccag taaatgacga 4741 aaagaataat tcgctttatc ttaaatataa gaaactggct gatcaggata acaatgtgat 4801 ttttggaggt cgattggcag aatatagata ttatgatatg catcaaatag taacaaaagc 4861 tttaagccat tttaaatgaa ggcatatgtt aatatatcta atttttgaag gtgtattttt 4921 atgtgattaa atataaaaaa actgtctata tagtattata attcaataat atggataaga 4981 taaaaactgt ttatgtcggt atgagtgctg acataattca cccggggcat ctcaacataa 5041 ttcatgaggc aaataagctt ggtcgtgttg tggtaggggt attaacggat tcggcaatag 5101 ctagttacaa gcggttgcct tatctgtcat ttgaacaacg ttcacttatt gttgagaatc 5161 tgaaaggggt ggatgaagtc atacctcaga ctactcttga ttatgtaccg aatttggaga 5221 aaatccgtcc aaattatgtt cttcacggtg atgattggaa agagggggtt cagcagaaga 5281 cgcgtcagca tgttatcgat tgcatttcac aatggggagg taaggttata gatattcctt 5341 atactcaagg tatttcttct tcattgctta accaacatct gaaagagata ggtacaaccc 5401 ctgaagtccg aatgaaaaga cttcgccggc tgattgctgc taagcctatt gtacgtattc 5461 ttgaaagtca ttcaggactt actggtctta ttgcggaaaa tgcttgcatt gaaattaata 5521 atgtgaagcg tgagttcgac ggtatgtggg catcttcatt gaccgattct acctcaaagg 5581 gtaaaccgga tatagaggct gtcgacttga cgacacggct tcatggtctt aacgatgctc 5641 tcgaagtaac tacaaaaccg tttatttatg atggtgatac tggtggaaaa ttagagcatt 5701 ttgttttcac tgttcgcact ttagaacgtc tgggagtttc tgctgttatc attgaggata 5761 aagtgggatt aaagcaaaat tcactattcg gtacagacgc tattcagaca caggatacta 5821 tcgaaggatt tacagcaaag attaaggcgg gcaaaaatgc tcagattact gaagacttta 5881 tgattatagc acgttgtgaa tcgcttattg caggtaagcc aatgtctgat gctattgagc 5941 gttgctttgc ttatgtggag gctggtgttg atggtatcat gattcattca aaggaaaaaa 6001 caggtgagga tatcaaggaa ttctgtaaaa aatttcgtgc aagatatgcg gatataccca 6061 ttgtggttgt tccgacaacc tataatcagt ttacagagga ggagttggct tcatggggaa 6121 taaatgtggt aatatatgca aatcacatgc ttcgtgcatc ttatccagca atgatgaatt 6181 gtgccaagtc tatcttgaca catggtcgtt caaaagaggc ttctgcagaa tactgcatgc 6241 ctatcaaaga gattcttgaa ctcatcccta gtacacataa ataaaataat ataatgatta 6301 gtccgaaatt ttttatagac gaattggata ggtatggtat tgactatttt gcaggtgtac 6361 cggattcgct actgaagagt atctgtggat acatagccga caatatggat gctaggcaca 6421 acattataac tgctaatgaa ggtgctgctg ttgctcttgc ggctggttat catttagcca 6481 caggaaaggt aggtgttgta tacatgcaga actctggtga gggaaatgcc ataaatccat 6541 tggcttcact agtagataag gaagtctata atataccgat tcttcttctg attggttggc 6601 gtggttgtcc tggggtgcaa gatgaaccac aacatgtaaa acagggcaag gtgacaaccg 6661 gattgcttaa tattatggga gtgaactatg atgtgctttc aaaagaagaa aacaaggctg 6721 caaagcaaat attaaaagct gtagaggcgg ttaaacggaa tgaggtctat gcccttatca 6781 ttgaaaaaga cacctttaat gcctatactc ttcaaaatgt agagagaaat aattttacga 6841 tgtctcgtga agaggctatt caaacagttg tagcagcact tggtgaagct gatactatta 6901 tatctactac aggtatgata agtcgtgaac tcttcgagta ccgtactgct atgaatcaag 6961 gacatgagcg cgattttttg acagtagggg ctatgggaca tgcctctcaa atagctttag 7021 gcatagcttt agagaagcaa gatcgcaaag tgtggtgttt tgatggtgat ggagcttcta 7081 ttatgcatat gggtagtatg gctattgtgg ctaataaagc gcctcagaac tatgttcatg 7141 tagtttttaa taatggtgct cacgactcgg tcggaggtca gcctactgta ggtttgaaga 7201 ttgatatacc tgctatagct aaagctatgg ggtataaaca tgtttataat gtcgatacaa 7261 aggaggggct acaagaattg attggtgaaa tcaaagtcca agaaggacca attttcttgc 7321 aggcatgtgt caagcagggc aatcgcaagg atttaggtcg tcccactact acacctattc 7381 agaataagga agctctgatg acttttttaa ggagttagat ttatataata tgcaaataat 7441 atatcaagga attgattatc ttaatgaagc tctcaaaggt tctaccaagg tgctattagt 7501 ttgtggtagt agctttcctt atcttggtat taaggataag atagaacata ttggtactcc 7561 cttcatggtg tttgatcagt ttacttctaa tcctctttat gaagatatct gtaggggggt 7621 agaccttttc cagattactc aatgcgacac aattcttgct attggtggtg gtagctcaat 7681 ggacgtggct aaatgtgtaa agctatattg tcaaatgtca aaagataagc cctatttgca 7741 gcaagagtac aaagatactg gcgtgaaact gattgccatt cctactacgg caggttcagg 7801 gtctgaatct acctgctatg ccgttattta tcatgatggt aagaaacaga gcgtgatgca 7861 caaaagtatt attcctgatg tcgtcattct tgaaccaaag ttgctcaaga ctcttcccgt 7921 ttatcagaag aaatgtacta tgcttgatgc tctttgtcaa ggtattgaat cttggtggtc 7981 tgtgaactcc actgacgaga gcaagcgtta ttccaagata gctgttgaga caatcataaa 8041 gtattggcgt gagtatattt ttgaaaatac agacttttca gctgaacaga tcatgttggc 8101 tgctaactat gctggtcgtg ccatttgcat aactcaaact acggccgcac atgctttcag 8161 ttataagatt acttctctat ataaacttcc tcatggtcat gctgtggcag taggactttc 8221 agaaatatgg gaatatatgt tgttgaacat gaacaaatgt ttagaacctc gcggtgaaga 8281 atatctttgg ggcatctttg ctgacatttc taaagctatg gggtgcttaa ctttggagca 8341 agctgttgtc aagtttcgcc aaatattgac agaaatggaa atcacaaacc cggttgctat 8401 taataagaca gaggagattg aaattctttc ccattcagtt aatcccgtta ggctgaagaa 8461 taatcctgtg gaactttgcg aatttactat taagtctctt tatgagatta ttattaaata 8521 gatatctatg agtttattca atgaataagg agtattaagt gatgatctaa aataatagcc 8581 gtttacttac acttttatga cacaatatat aaattcgctt gaagaagaga tgcggagtgg 8641 ttttttggtt acgcgtcaaa gcaaacacgt atggaatata cagatagaaa tgacattggc 8701 acttcttgag gtatgtaaaa aatataatct tcgtatatgg gcaataagtg gaacgatgct 8761 gggagctgtg cggcataaag gatttattcc atgggatgat gatatggatt tttttatgtt 8821 cagagaagat tatgaccgtt tattagaaat agcttcggat gaatttaaaa aacctatatt 8881 ctttcagtgt gcttatactg aaaaaggata ttatagaggg catgctcaga tgcgttatga 8941 caatacagct atgatattgt tatatgaagg agaaatcggc gttaaatttc atcaggggat 9001 atttatagat atatttgtag ctgacggatt tcctgaagat aaagaagaaa gagaacaact 9061 tatagaacag agaaactgca ttctaaatta tttatgggga agaaattatc ctctgagacg 9121 gttctcttcc ataccgaatt tgataaaata catttctgct aaacgaaagt tgggggaaaa 9181 ggcttcgtgg actgatattg aactttattc ttacatggaa caacttcatc gtaactattc 9241 tgttaacaga aattcaagga attgttgtat tcaatttact tatttgccta gatatgtgag 9301 aaatacagaa tggttcgatg aaacagtctg gataccattt gagagaatag aattgcctgt 9361 tcctttggca tatcatgaag tgttgaagca tgaatatggt gattatatga aaccgatcaa 9421 gggggcgagt cttcatggta atttggtggt agatgtagat gaatcttacg agaaatatct 9481 ttcaggtctg aagatgtctt ttctaaaagc tacatatttg tttataaagt cagggggcgg 9541 gatggtgctt cgtgtatttg gtttgagaaa aaagtaaatt taggatagcg gcgactacgt 9601 tatgaaagat aaagctgtca acggtgtttt ttggacttcg gtggaaagaa ttggtagtca 9661 ggtgcttagt cttcttgtag gaatagcagt tgcgaggatt ctatctccag aagattatgg 9721 tataatagga atgactgcca ttttcttagc agtagcttct actcttcttg acagcggatt 9781 tggtagcgca ctaatacaaa atcaaaatag aacagaaact gattattcta cttgctttta 9841 ttttaatata gttgtaggtc tgttttggta tgtagtattg tttttagcag ctccgctaat 9901 agcagacttt tatcgtacgc cattgctgga atcggtttgc agagttctag gtttggtttt 9961 tgtattcaat tcacttacaa tttcgcagac ggcacggctt accgtagaat ttagatttcg 10021 ggaactgtgt ttcgttacat taggtacgca gttgttaacg ggaattgttg gtttcattat 10081 ggcatttaaa ggttatggag tatgggcgtt ggtgtttcag caagtaggcg cagctttttt 10141 aagagtatgt ctgatagaat ggattacaca ttggaaaccg ttacccttgt tttccaagat 10201 tgcattttgt agaatgtttt catttggttc taaaatacta tgttcaggca ttataaatac 10261 tgtttatgac aatatctata cattagtgat agggcgtgtc ttttcacctg tagaagttgg 10321 attctataat agaggaaatc agtttgcaca attaccatct caaagtttgc tatctgttgt 10381 tatgaaagtc gtttatccat tgatggcaga agtgcaagat gattcggaaa aactttgtag 10441 agcttatcag aaatttttgc gtatttcggt tttcattctt tatcctattc ttattgggtt 10501 aatagtctta gcagagtctt ttatttatgt attgctaggc gataaatggt tgccttgtgt 10561 tcccttgatg caaatattat gttttagcta cttgtttgac ccacttacac atataaatct 10621 taatattttg tatgtaagag gacggactga tttagtactt aaactagaac ttataaagaa 10681 accgatagca ttgattattt tgtttggaat gctaccattc gggttatggt ggctgtgtgc 10741 aggacgtgct ttgtacagtt ttatagcgta ctgctttaat tgtttttata ctggaaagtt 10801 tattagattt ggttttaggc aacagatgta ctatagtgta cctgtgattg taaaatctgc 10861 tttgatgggg attatttgtt ggagaacagc attaggcttt gaagaaccat ggttaaagtt 10921 gatggtagga tttttggcag gattgctttc ttatatagga ctgaatttta taagtcatga 10981 tgaaagtttt tttgatataa aagggataat attgaaaaat gggaaatgat aaataatata 11041 ataatgaaca aaatattatc tgtagttatt ccttcgtata atatggagga gtatttgtac 11101 cgaaatgtga gtagcatgat gattggggaa atattagatg accttgaaat cattattgtt 11161 aatgacggaa gtaaggatag aacgtctgaa atagcacatg aacttcaaag aaaagcttct 11221 caaagtattg ttgttattga taaggaaaac ggtcattatg gttcatgtgt aaatgcagcg 11281 ttgaagatag caacaggcaa atattttcga attttggatg cggatgactg gatggatagc 11341 ggtgaatttg taaaatttgt aaatatattg aagtgtattg atgtagactg tatctataca 11401 ccttttgcga atgttttttt taataaaaat agaaaggaat attgtattgc tgataatgca 11461 gtgtggaata aaaagataga tctgagtcat gtctcattgc ccccttctta ttttcacatg 11521 cactcattga cttatcggac tcatttgtta cataaaataa gttttgtgca ggaagaaaag 11581 atttgttata cggattcaga gtatgttttt tatcctttgt ctcatgcaaa atcgttatac 11641 tgtattaatg tttgccctta tcagtattat ataggtcgcg aaggacaatc tgtatcattg 11701 gattctttga gtaaaaacta tgctcatttt gagaaagtat tggcaaatat cagtttttat 11761 aagcctatgg aattgttacc gacatattca tcacttagaa aatattatat tgtgacgctg 11821 ctacgttata tgcttgatat tcatcttttt tcacagaaaa aggatgttca gagagacaag 11881 ctattaagag acaaaataag ggcttttggt gatgacgtta acattagtga acaaattaaa 11941 gacatcaatc ttaaggggtt gcattatatt aattggtggt tggataatac aggtgttgat 12001 aaattaaaac ttaaaattct tgtcttatta aaaaaagtac aacatacaat agttaattga 12061 aatgcctaaa attagcgtaa taataccggt gtataaagta gaacaattta tagaaaggtg 12121 tgcaattagt cttttcgaac aaactttaga cgatattgaa tatcttttca tagatgattg 12181 ttcacctgat aattcagtgg agattattaa aaatgttttg atgcgatatg aaacaagaaa 12241 agattcggtt cgtattatat ctatgcaaaa gaattgtgga caagctgctg tgcgtagata 12301 tggcaatagt atagctcgtg gtgattatat aattcattgt gacggagacg attgggtgga 12361 tattaatatg tactacaaaa tgtacgagtg tgctgtcaat aataagttag atattgtcag 12421 gtgtaaattt tgtagaacag atggaaagtt aatgaaagaa tgtattaata tcccaagtaa 12481 tatatattgt gatgcaaaaa aaatgatttc ctacttgtta aggttatctg atttatcttc 12541 aacttgcgat aaattggtaa gacgggaact ttatcaatca gtagatttta tatatcctgt 12601 tgataatatg tgtgaagatt tcgcaattgt aactcaattg ttttgtcgta ctgataaaat 12661 tggatatata gatgaagttc tctattttta ttatcaaaat aaattttcaa taagtcatat 12721 attggataat actcatatag ataataaggc acaacaaata agcaataatg taaaactgat 12781 aggaaaaatt ttgaaaacaa aatatccagg tggaattttc gataaagaaa ttgaagtaat 12841 taaattgatg gcaaaaaatg cctatagacc tattataaga agagaagggt attatgaaaa 12901 gtggaaaaca ttatataagg aaataaattc gaaaatattt ttcaatgaat atataacaat 12961 aaaagaaaaa ttgtcattta tagcttgcta tatcgggata tatcctttgt tgactgggcg 13021 taaatagtaa atatgggaaa tatagaaaat tgtatatatt taattacttt gtttttgttt 13081 gagatattat tatttcttta tgtatggcag aagtttgata gatctatttt ttctccatca 13141 atatatacta tcggtgtttt aggatttgga acattgctga atatttggtg tgttgattat 13201 tgggatatta gttttcatcc acgtacattt ggaattatag ctttaggatt atgcatgatg 13261 gttattgctg aaaaaaatgc ttatataaaa agacgtaatg atagtgaata taagatgttt 13321 tatatttctt tacctcctat gttagttatc tctgtggctg catattgcat tgtagcaaca 13381 tttttgtatt ttaatgaaat acgtagattg gggttagcgc aatctttggc ggtttcagaa 13441 gcgataggta atataaagga aaattttgag gaatttgaag aattatttaa cccatttatt 13501 cggcaaggat ataaaatagt t //